gH625: A milestone in understanding the many roles of membranotropic peptides (513 views)
Bba-Gen Subjects (ISSN: 0925-4439, 0006-3002, 1570-9639), 2015 Jan; 1848(PA): 16-25.
Export to BibTeX Export to EndNote
Paper type: Journal Article, Review,
Impact factor: 5.158, 5-year impact factor: 5.36
Url: http://www.scopus.com/inward/record.url?eid=2-s2.0-84908193841&partnerID=40&md5=90b30034e2cbfaad63fa46111e4be207
Keywords: Delivery, Fusion, Hydrophobicity, Membranotropic Peptide, Viral Inhibition, Antivirus Agent, Doxorubicin, Liposome, Nanoparticle, Polystyrene, Protein Gh625, Unclassified Drug, Virus Fusion Protein, Virus Protein, Bilayer Membrane, Blood Brain Barrier, Cell Membrane Transport, Drug Delivery System, Drug Design, Herpes Simplex Virus 1, Human, In Vitro Study, In Vivo Study, Molecular Mechanics, Nonhuman, Review, Virus Entry, Virus Inhibition, Amino Acid Sequence, Cell Membrane Metabolism Virology, Herpes Simplex Metabolism Virology, Herpesvirus 1, Human Metabolism Physiology, Host-Pathogen Interactions, Models, Molecular Sequence Data, Peptides Chemistry Metabolism, Protein Conformation, Viral Envelope Proteins Chemistry Metabolism, Gh625 Peptide, Herpes Simplex Virus Type I, Virus Envelope Protein, Chemical Structure, Host Pathogen Interaction, Molecular Genetics,
Affiliations:
*** IBB - CNR ***
Department of Pharmacy, University of Naples Federico II, Via Mezzocannone 16Naples, Italy
DFM Scarl, University of Naples Federico II, Via Mezzocannone 16Naples, Italy
Department of Experimental Medicine, II University of Naples, Via De Crecchio 7Naples, Italy
References:
Craik, D.J., Fairlie, D.P., Liras, S., Price, D., The future of peptide-based drugs (2013) Chem. Biol. Drug Des., 81, pp. 136-14
Vlieghe, P., Lisowski, V., Martinez, J., Khrestchatisky, M., Synthetic therapeutic peptides: Science and market (2010) Drug Discov. Today, 15, pp. 40-56
Sato, A.K., Viswanathan, M., Kent, R.B., Wood, C.R., Therapeutic peptides: Technological advances driving peptides into development (2006) Curr. Opin. Biotechnol., 17, pp. 638-642
Yau, W.M., Wimley, W.C., Gawrisch, K., White, S.H., The preference of tryptophan for membrane interfaces (1998) Biochemistry, 37, pp. 14713-14718
Harris, F., Wallace, J., Phoenix, D.A., Use of hydrophobic moment plot methodology to aid the identification of oblique orientated α-helices (2000) Mol. Membr. Biol., 17, pp. 201-207
Joanne, P., Nicolas, P., El Amri, C., Antimicrobial peptides and viral fusion peptides: How different they are? (2009) Protein Pept. Lett., 16, pp. 743-750
Cruz, J., Ortiz, C., Guzman, F., Fernandez-Lafuente, R., Torres, R., Antimicrobial peptides: Promising compounds against pathogenic microorganisms (2014) Curr. Med. Chem., 21, pp. 2299-2321
Falanga, A., Cantisani, M., Pedone, C., Galdiero, S., Membrane fusion and fission: Enveloped viruses (2009) Protein Pept. Lett., 16, pp. 751-759
Wang, F., Wang, Y., Zhang, X., Zhang, W., Guo, S., Jin, F., Recent progress of cell-penetrating peptides as new carriers for intracellular cargo delivery (2014) J. Control. Release, 174, pp. 126-136
Harrison, S.C., Mechanism of membrane fusion by viral envelope proteins (2005) Adv. Virus Res., 64, pp. 231-261
Harrison, S.C., Viral membrane fusion (2008) Nat. Struct. Mol. Biol., 15, pp. 690-698
Wilson, I.A., Skehel, J.J., Wiley, D.C., Structure of the haemagglutinin membrane glycoprotein of influenza virus at 3 A resolution (1981) Nature, 289, pp. 366-373
Fass, D., Harrison, S.C., Kim, P.S., Retrovirus envelope domain at 1.7 angstrom resolution (1996) Nat. Struct. Biol., 3, pp. 465-469
Weissenhorn, W., Carfi, A., Lee, K.H., Skehel, J.J., Wiley, D.C., Crystal structure of the Ebola virus membrane fusion subunit, GP2, from the envelope glycoprotein ectodomain (1998) Mol. Cell, 2, pp. 605-616
Yin, H.S., Wen, X., Paterson, R.G., Lamb, R.A., Jardetzky, T.S., Structure of the parainfluenza virus 5 F protein in its metastable, prefusion conformation (2006) Nature, 439, pp. 38-44
Xu, Y., Liu, Y., Lou, Z., Qin, L., Li, X., Bai, Z., Pang, H., Rao, Z., Structural basis for coronavirus-mediated membrane fusion. Crystal structure of mouse hepatitis virus spike protein fusion core (2004) J. Biol. Chem., 279, pp. 30514-30522
Rey, F.A., Heinz, F.X., Mandl, C., Kunz, C., Harrison, S.C., The envelope glycoprotein from tick-borne encephalitis virus at 2 Å resolution (1995) Nature, 375, pp. 291-298
Lescar, J., Roussel, A., Wien, M.W., Navaza, J., Fuller, S.D., Wengler, G., Rey, F.A., The fusion glycoprotein shell of Semliki Forest virus: An icosahedral assembly primed for fusogenic activation at endosomal pH (2001) Cell, 105, pp. 137-148
Backovic, M., Jardetzky, T., Class III viral membrane fusion proteins (2011) Cell Fusion in Health and Disease, pp. 91-101. , T. Dittmar, K.S. Zänker, Springer Netherlands
White, S.H., Wimley, W.C., Hydrophobic interactions of peptides with membrane interfaces (1998) Biochim. Biophys. Acta Rev. Biomembr., 1376, pp. 339-352
Wimley, W.C., White, S.H., Experimentally determined hydrophobicity scale for proteins at membrane interfaces (1996) Nat. Struct. Biol., 3, pp. 842-848
Wimley, W.C., Hristova, K., Ladokhin, A.S., Silvestro, L., Axelsen, P.H., White, S.H., Folding of β-sheet membrane proteins: A hydrophobic hexapeptide model (1998) J. Mol. Biol., 277, pp. 1091-1110
Ladokhin, A.S., White, S.H., Folding of amphipathic α-helices on membranes: Energetics of helix formation by melittin (1999) J. Mol. Biol., 285, pp. 1363-1369
Segrest, J.P., De Loof, H., Dohlman, J.G., Brouillette, C.G., Anantharamaiah, G.M., Amphipathic helix motif: Classes and properties (1990) Proteins Struct. Funct. Bioinforma., 8, pp. 103-117
Han, X., Tamm, L.K., PH-dependent self-association of influenza hemagglutinin fusion peptides in lipid bilayers (2000) J. Mol. Biol., 304, pp. 953-965
Sáez-Cirión, A., Nieva, J.L., Conformational transitions of membrane-bound HIV-1 fusion peptide (2002) Biochim. Biophys. Acta Biomembr., 1564, pp. 57-65
Han, X., Bushweller, J.H., Cafiso, D.S., Tamm, L.K., Membrane structure and fusion-triggering conformational change of the fusion domain from influenza hemagglutinin (2001) Nat. Struct. Biol., 8, pp. 715-720
Tamm, L.K., Han, X., Li, Y., Lai, A.L., Structure and function of membrane fusion peptides (2002) Biopolym. Pept. Sci. Sect., 66, pp. 249-260
Agopian, A., Castano, S., Structure and orientation study of Ebola fusion peptide inserted in lipid membrane models (2014) Biochim. Biophys. Acta Biomembr., 1838, pp. 117-126
Apellaniz, B., Huarte, N., Largo, E., Nieva, J.L., The three lives of viral fusion peptides (2014) Chem. Phys. Lipids, 181, pp. 40-55
Lai, A.L., Moorthy, A.E., Li, Y., Tamm, L.K., Fusion activity of HIV gp41 fusion domain is related to its secondary structure and depth of membrane insertion in a cholesterol-dependent fashion (2012) J. Mol. Biol., 418, pp. 3-15
Larsson, P., Kasson, P.M., Lipid tail protrusion in simulations predicts fusogenic activity of influenza fusion peptide mutants and conformational models (2013) PLoS Comput. Biol., 9, p. 1002950
Kozlov, M.M., McMahon, H.T., Chernomordik, L.V., Protein-driven membrane stresses in fusion and fission (2010) Trends Biochem. Sci., 35, pp. 699-706
Peisajovich, S.G., Samuel, O., Shai, Y., Paramyxovirus F1 protein has two fusion peptides: Implications for the mechanism of membrane fusion (2000) J. Mol. Biol., 296, pp. 1353-1365
Perez-Berna, A.J., Guillen, J., Moreno, M.R., Bernabeu, A., Pabst, G., Laggner, P., Villalain, J., Identification of the membrane-active regions of hepatitis C virus p7 protein: Biophysical characterization of the loop region (2008) J. Biol. Chem., 283, pp. 8089-8101
Nemesio, H., Palomares-Jerez, F., Villalain, J., The membrane-active regions of the dengue virus proteins C and e (2011) Biochim. Biophys. Acta, 1808, pp. 2390-2402
Galdiero, S., Falanga, A., Vitiello, M., Browne, H., Pedone, C., Galdiero, M., Fusogenic domains in herpes simplex virus type 1 glycoprotein H (2005) J. Biol. Chem., 280, pp. 28632-28643
Galdiero, S., Vitiello, M., D'Isanto, M., Falanga, A., Cantisani, M., Browne, H., Pedone, C., Galdiero, M., The identification and characterization of fusogenic domains in herpes virus glycoprotein B molecules (2008) Chembiochem, 9, pp. 758-767
Lorizate, M., Huarte, N., Saez-Cirion, A., Nieva, J.L., Interfacial pre-transmembrane domains in viral proteins promoting membrane fusion and fission (2008) Biochim. Biophys. Acta, 1778, pp. 1624-1639
D'Errico, G., D'Ursi, A.M., Marsh, D., Interaction of a peptide derived from glycoprotein gp36 of feline immunodeficiency virus and its lipoylated analogue with phospholipid membranes (2008) Biochemistry, 47, pp. 5317-5327
Badani, H., Garry, R.F., Wimley, W.C., Peptide entry inhibitors of enveloped viruses: The importance of interfacial hydrophobicity (2014) Biochim. Biophys. Acta Biomembr, 1838, pp. 2180-2197
Rapaport, D., Ovadia, M., Shai, Y., A synthetic peptide corresponding to a conserved heptad repeat domain is a potent inhibitor of Sendai virus-cell fusion: An emerging similarity with functional domains of other viruses (1995) EMBO J., 14, pp. 5524-5531
Xu, Y., Rahman, N.A., Othman, R.B., Hu, P., Huang, M., Computational identification of self-inhibitory peptides from envelope proteins (2012) Proteins, 80, pp. 2154-2168
Chang, D.K., Cheng, S.F., Lin, C.H., Kantchev, E.B., Wu, C.W., Self-association of glutamic acid-rich fusion peptide analogs of influenza hemagglutinin in the membrane-mimic environments: Effects of positional difference of glutamic acids on side chain ionization constant and intra- and inter-peptide interactions deduced from NMR and gel electrophoresis measurements (2005) Biochim. Biophys. Acta, 1712, pp. 37-51
Lau, W.L., Ege, D.S., Lear, J.D., Hammer, D.A., Degrado, W.F., Oligomerization of fusogenic peptides promotes membrane fusion by enhancing membrane destabilization (2004) Biophys. J., 86, pp. 272-284
Kliger, Y., Aharoni, A., Rapaport, D., Jones, P., Blumenthal, R., Shai, Y., Fusion peptides derived from the HIV type 1 glycoprotein 41 associate within phospholipid membranes and inhibit cell-cell fusion. Structure-function study (1997) J. Biol. Chem., 272, pp. 13496-13505
Pritsker, M., Jones, P., Blumenthal, R., Shai, Y., A synthetic all D-amino acid peptide corresponding to the N-terminal sequence of HIV-1 gp41 recognizes the wild-type fusion peptide in the membrane and inhibits HIV-1 envelope glycoprotein-mediated cell fusion (1998) Proc. Natl. Acad. Sci. U. S. A., 95, pp. 7287-7292
Li, Y., Han, X., Tamm, L.K., Thermodynamics of fusion peptide-membrane interactions (2003) Biochemistry, 42, pp. 7245-7251
Forssmann, W.G., The, Y.H., Stoll, M., Adermann, K., Albrecht, U., Tillmann, H.C., Barlos, K., Schmidt, R.E., Short-term monotherapy in HIV-infected patients with a virus entry inhibitor against the gp41 fusion peptide (2010) Sci. Transl. Med., 2, p. 63re63
Münch, J., Ständker, L., Adermann, K., Schulz, A., Schindler, M., Chinnadurai, R., Pöhlmann, S., Kirchhoff, F., Discovery and optimization of a natural HIV-1 entry inhibitor targeting the gp41 fusion peptide (2007) Cell, 129, pp. 263-275
Torchilin, V.P., Multifunctional nanocarriers (2006) Adv. Drug Deliv. Rev., 58, pp. 1532-1555
Bareford, L.M., Swaan, P.W., Endocytic mechanisms for targeted drug delivery (2007) Adv. Drug Deliv. Rev., 59, pp. 748-758
He, J., Kauffman, W.B., Fuselier, T., Naveen, S.K., Voss, T.G., Hristova, K., Wimley, W.C., Direct cytosolic delivery of polar cargo to cells by spontaneous membrane-translocating peptides (2013) J. Biol. Chem., 288, pp. 29974-29986
Guarnieri, D., Falanga, A., Muscetti, O., Tarallo, R., Fusco, S., Galdiero, M., Galdiero, S., Netti, P.A., Shuttle-mediated nanoparticle delivery to the blood-brain barrier (2013) Small, 9, pp. 853-862
Almeida, P.F., Membrane-active peptides: Binding, translocation, and flux in lipid vesicles (2014) Biochim. Biophys. Acta, 1838, pp. 2216-2227
Heitz, F., Morris, M.C., Divita, G., Twenty years of cell-penetrating peptides: From molecular mechanisms to therapeutics (2009) Br. J. Pharmacol., 157, pp. 195-206
Vivès, E., Brodin, P., Lebleu, B., Truncated HIV-1 Tat protein basic domain rapidly translocates through the plasma membrane (1997) J. Biol. Chem., 272, pp. 16010-16017
Angeles-Boza, A.M., Erazo-Oliveras, A., Lee, Y.-J., Pellois, J.-P., Generation of endosomolytic reagents by branching of cell-penetrating peptides (2010) Bioconjug. Chem., 21, pp. 2164-2167
Morris, M.C., Chaloin, L., Mery, J., Heitz, F., Divita, G., A novel potent strategy for gene delivery using a single peptide vector as a carrier (1999) Nucleic Acids Res., 27, pp. 3510-3517
Morris, M.C., Vidal, P., Chaloin, L., Heitz, F., Divita, G., A new peptide vector for efficient delivery of oligonucleotides into mammalian cells (1997) Nucleic Acids Res., 25, pp. 2730-2736
Gallaher, W.R., Detection of a fusion peptide sequence in the transmembrane protein of human immunodeficiency virus (1987) Cell, 50, pp. 327-328
Kalderon, D., Smith, A.E., In vitro mutagenesis of a putative DNA binding domain of SV40 large-T (1984) Virology, 139, pp. 109-137
Delboy, M.G., Patterson, J.L., Hollander, A.M., Nicola, A.V., Nectin-2-mediated entry of a syncytial strain of herpes simplex virus via pH-independent fusion with the plasma membrane of Chinese hamster ovary cells (2006) Virol. J., 3, p. 105
Roller, D.G., Dollery, S.J., Doyle, J.L., Nicola, A.V., Structure-function analysis of herpes simplex virus glycoprotein B with fusion-from-without activity (2008) Virology, 382, pp. 207-216
Arii, J., Uema, M., Morimoto, T., Sagara, H., Akashi, H., Ono, E., Arase, H., Kawaguchi, Y., Entry of herpes simplex virus 1 and other alphaherpesviruses via the paired immunoglobulin-like type 2 receptor alpha (2009) J. Virol., 83, pp. 4520-4527
Milne, R.S., Nicola, A.V., Whitbeck, J.C., Eisenberg, R.J., Cohen, G.H., Glycoprotein D receptor-dependent, low-pH-independent endocytic entry of herpes simplex virus type 1 (2005) J. Virol., 79, pp. 6655-6663
Connolly, S.A., Jackson, J.O., Jardetzky, T.S., Longnecker, R., Fusing structure and function: A structural view of the herpesvirus entry machinery (2011) Nat. Rev. Microbiol., 9, pp. 369-381
Turner, A., Bruun, B., Minson, T., Browne, H., Glycoproteins gB, gD, and gHgL of herpes simplex virus type 1 are necessary and sufficient to mediate membrane fusion in a Cos cell transfection system (1998) J. Virol., 72, pp. 873-875
Farnsworth, A., Wisner, T.W., Webb, M., Roller, R., Cohen, G., Eisenberg, R., Johnson, D.C., Herpes simplex virus glycoproteins gB and gH function in fusion between the virion envelope and the outer nuclear membrane (2007) Proc. Natl. Acad. Sci. U. S. A., 104, pp. 10187-10192
Falanga, A., Tarallo, R., Vitiello, G., Vitiello, M., Perillo, E., Cantisani, M., D'Errico, G., Galdiero, S., Biophysical characterization and membrane interaction of the two fusion loops of glycoprotein B from herpes simplex type i virus (2012) PLoS One, 7, p. 32186
Galdiero, S., Russo, L., Falanga, A., Cantisani, M., Vitiello, M., Fattorusso, R., Malgieri, G., Isernia, C., Structure and orientation of the gH625-644 membrane interacting region of herpes simplex virus type 1 in a membrane mimetic system (2012) Biochemistry, 51, pp. 3121-3128
Chowdary, T.K., Cairns, T.M., Atanasiu, D., Cohen, G.H., Eisenberg, R.J., Heldwein, E.E., Crystal structure of the conserved herpesvirus fusion regulator complex gH-gL (2010) Nat. Struct. Mol. Biol., 17, pp. 882-888
Matsuura, H., Kirschner, A.N., Longnecker, R., Jardetzky, T.S., Crystal structure of the Epstein-Barr virus (EBV) glycoprotein H/glycoprotein L (gH/gL) complex (2010) Proc. Natl. Acad. Sci. U. S. A., 107, pp. 22641-22646
Heldwein, E.E., Lou, H., Bender, F.C., Cohen, G.H., Eisenberg, R.J., Harrison, S.C., Crystal structure of glycoprotein B from herpes simplex virus 1 (2006) Science, 313, pp. 217-220
Connolly, S.A., Longnecker, R., Residues within the C-terminal arm of the herpes simplex virus 1 glycoprotein B ectodomain contribute to its refolding during the fusion step of virus entry (2012) J. Virol., 86, pp. 6386-6393
Cantisani, M., Falanga, A., Incoronato, N., Russo, L., De Simone, A., Morelli, G., Berisio, R., Galdiero, S., Conformational modifications of gB from herpes simplex virus type 1 analyzed by synthetic peptides (2013) J. Med. Chem., 56, pp. 8366-8376
Backovic, M., Longnecker, R., Jardetzky, T.S., Structure of a trimeric variant of the Epstein-Barr virus glycoprotein B (2009) Proc. Natl. Acad. Sci. U. S. A., 106, pp. 2880-2885
Roche, S., Bressanelli, S., Rey, F.A., Gaudin, Y., Crystal structure of the low-pH form of the vesicular stomatitis virus glycoprotein G (2006) Science, 313, pp. 187-191
Kadlec, J., Loureiro, S., Abrescia, N.G., Stuart, D.I., Jones, I.M., The postfusion structure of baculovirus gp64 supports a unified view of viral fusion machines (2008) Nat. Struct. Mol. Biol., 15, pp. 1024-1030
Akkarawongsa, R., Pocaro, N.E., Case, G., Kolb, A.W., Brandt, C.R., Multiple peptides homologous to herpes simplex virus type 1 glycoprotein B inhibit viral infection (2009) Antimicrob. Agents Chemother., 53, pp. 987-996
Vitiello, G., Falanga, A., Galdiero, M., Marsh, D., Galdiero, S., D'Errico, G., Lipid composition modulates the interaction of peptides deriving from herpes simplex virus type i glycoproteins B and H with biomembranes (2011) Biochim. Biophys. Acta, 1808, pp. 2517-2526
Krishnan, A., Verma, S.K., Mani, P., Gupta, R., Kundu, S., Sarkar, D.P., A histidine switch in hemagglutinin-neuraminidase triggers paramyxovirus-cell membrane fusion (2009) J. Virol., 83, pp. 1727-1741
Chanel-Vos, C., Kielian, M., A conserved histidine in the ij loop of the Semliki Forest virus E1 protein plays an important role in membrane fusion (2004) J. Virol., 78, pp. 13543-13552
Tarallo, R., Carberry, T.P., Falanga, A., Vitiello, M., Galdiero, S., Galdiero, M., Weck, M., Dendrimers functionalized with membrane-interacting peptides for viral inhibition (2013) Int. J. Nanomedicine, 8, pp. 521-534
Tu, Y., Kim, J.S., A fusogenic segment of glycoprotein H from herpes simplex virus enhances transfection efficiency of cationic liposomes (2008) J. Gene Med., 10, pp. 646-654
Tarallo, R., Accardo, A., Falanga, A., Guarnieri, D., Vitiello, G., Netti, P., D'Errico, G., Galdiero, S., Clickable functionalization of liposomes with the gH625 peptide from Herpes simplex virus type i for intracellular drug delivery (2011) Chemistry, 17, pp. 12659-12668
Carberry, T.P., Tarallo, R., Falanga, A., Finamore, E., Galdiero, M., Weck, M., Galdiero, S., Dendrimer functionalization with a membrane-interacting domain of herpes simplex virus type 1: Towards intracellular delivery (2012) Chemistry, 18, pp. 13678-13685
Smaldone, G., Falanga, A., Capasso, D., Guarnieri, D., Correale, S., Galdiero, M., Netti, P.A., Pedone, E., GH625 is a viral derived peptide for effective delivery of intrinsically disordered proteins (2013) Int. J. Nanomedicine, 8, pp. 2555-2565
Pinaud, F., Clarke, S., Sittner, A., Dahan, M., Probing cellular events, one quantum dot at a time (2010) Nat. Methods, 7, pp. 275-285
Medintz, I.L., Pons, T., Delehanty, J.B., Susumu, K., Brunel, F.M., Dawson, P.E., Mattoussi, H., Intracellular delivery of quantum dot-protein cargos mediated by cell penetrating peptides (2008) Bioconjug. Chem., 19, pp. 1785-1795
Lee, H., Kim, I.K., Park, T.G., Intracellular trafficking and unpacking of siRNA/quantum dot-PEI complexes modified with and without cell penetrating peptide: Confocal and flow cytometric FRET analysis (2010) Bioconjug. Chem., 21, pp. 289-295
Delehanty, J.B., Bradburne, C.E., Susumu, K., Boeneman, K., Mei, B.C., Farrell, D., Blanco-Canosa, J.B., Medintz, I.L., Spatiotemporal multicolor labeling of individual cells using peptide-functionalized quantum dots and mixed delivery techniques (2011) J. Am. Chem. Soc., 133, pp. 10482-10489
Cukierman, E., Khan, D.R., The benefits and challenges associated with the use of drug delivery systems in cancer therapy (2010) Biochem. Pharmacol., 80, pp. 762-770
Newkome, G.R., Moorefield, C.N., Vögtle, F., (2001) Dendrimers and Dendrons: Concepts, Synthesis, Applications, , Wiley-VCH Weinheim
Lee, C.C., Mackay, J.A., Fréchet, J.M.J., Szoka, F.C., Designing dendrimers for biological applications (2005) Nat. Biotechnol., 23, pp. 1517-1526
Gillies, E.R., Frechet, J.M., Dendrimers and dendritic polymers in drug delivery (2005) Drug Discov. Today, 10, pp. 35-43
Gunaseelan, S., Gunaseelan, K., Deshmukh, M., Zhang, X., Sinko, P.J., Surface modifications of nanocarriers for effective intracellular delivery of anti-HIV drugs (2010) Adv. Drug Deliv. Rev., 62, pp. 518-531
Najlah, M., D'Emanuele, A., Crossing cellular barriers using dendrimer nanotechnologies (2006) Curr. Opin. Pharmacol., 6, pp. 522-527
Seib, F.P., Jones, A.T., Duncan, R., Comparison of the endocytic properties of linear and branched PEIs, and cationic PAMAM dendrimers in B16f10 melanoma cells (2007) J. Control. Release, 117, pp. 291-300
Kang, H., Delong, R., Fisher, M.H., Juliano, R.L., Tat-conjugated PAMAM dendrimers as delivery agents for antisense and siRNA oligonucleotides (2005) Pharm. Res., 22, pp. 2099-2106
Lu, C.T., Zhao, Y.Z., Wong, H.L., Cai, J., Peng, L., Tian, X.Q., Current approaches to enhance CNS delivery of drugs across the brain barriers (2014) Int. J. Nanomedicine, 9, pp. 2241-2257
Abbott, N.J., Ronnback, L., Hansson, E., Astrocyte-endothelial interactions at the blood-brain barrier (2006) Nat. Rev. Neurosci., 7, pp. 41-53
Mahajan, S.D., Law, W.C., Aalinkeel, R., Reynolds, J., Nair, B.B., Yong, K.T., Roy, I., Schwartz, S.A., Nanoparticle-mediated targeted delivery of antiretrovirals to the brain (2012) Methods Enzymol., 509, pp. 41-60
Jain, K.K., Nanobiotechnology-based strategies for crossing the blood-brain barrier (2012) Nanomedicine (Lond.), 7, pp. 1225-1233
Orive, G., Ali, O.A., Anitua, E., Pedraz, J.L., Emerich, D.F., Biomaterial-based technologies for brain anti-cancer therapeutics and imaging (2010) Biochim. Biophys. Acta, 1806, pp. 96-107
Qiao, R., Jia, Q., Huwel, S., Xia, R., Liu, T., Gao, F., Galla, H.J., Gao, M., Receptor-mediated delivery of magnetic nanoparticles across the blood-brain barrier (2012) ACS Nano, 6, pp. 3304-3310
Valiante, S., Falanga, A., Cigliano, L., Iachetta, G., Busiello, R.A., La Marca, V., Galdiero, M., Galdiero, S., (2014) The Peptide gH625 Enters into Neuron and Astrocyte Cell Lines and Crosses the Blood Brain Barrier in Rats, , (submitted for publication)
Fawell, S., Seery, J., Daikh, Y., Moore, C., Chen, L.L., Pepinsky, B., Barsoum, J., Tat-mediated delivery of heterologous proteins into cells (1994) Proc. Natl. Acad. Sci., 91, pp. 664-668
Schutze-Redelmeier, M.P., Gournier, H., Garcia-Pons, F., Moussa, M., Joliot, A.H., Volovitch, M., Prochiantz, A., Lemonnier, F.A., Introduction of exogenous antigens into the MHC class i processing and presentation pathway by Drosophila antennapedia homeodomain primes cytotoxic T cells in vivo (1996) J. Immunol., 157, pp. 650-655
Borlongan, C.V., Emerich, D.F., Facilitation of drug entry into the CNS via transient permeation of blood brain barrier: Laboratory and preliminary clinical evidence from bradykinin receptor agonist, Cereport (2003) Brain Res. Bull., 60, pp. 297-306
Patel, M.M., Goyal, B.R., Bhadada, S.V., Bhatt, J.S., Amin, A.F., Getting into the brain: Approaches to enhance brain drug delivery (2009) CNS Drugs, 23, pp. 35-58
Craik, D. J., Fairlie, D. P., Liras, S., Price, D., The future of peptide-based drugs (2013) Chem. Biol. Drug Des., 81, pp. 136-14
Sato, A. K., Viswanathan, M., Kent, R. B., Wood, C. R., Therapeutic peptides: Technological advances driving peptides into development (2006) Curr. Opin. Biotechnol., 17, pp. 638-642
Yau, W. M., Wimley, W. C., Gawrisch, K., White, S. H., The preference of tryptophan for membrane interfaces (1998) Biochemistry, 37, pp. 14713-14718
Harrison, S. C., Mechanism of membrane fusion by viral envelope proteins (2005) Adv. Virus Res., 64, pp. 231-261
Harrison, S. C., Viral membrane fusion (2008) Nat. Struct. Mol. Biol., 15, pp. 690-698
Wilson, I. A., Skehel, J. J., Wiley, D. C., Structure of the haemagglutinin membrane glycoprotein of influenza virus at 3 A resolution (1981) Nature, 289, pp. 366-373
Yin, H. S., Wen, X., Paterson, R. G., Lamb, R. A., Jardetzky, T. S., Structure of the parainfluenza virus 5 F protein in its metastable, prefusion conformation (2006) Nature, 439, pp. 38-44
Rey, F. A., Heinz, F. X., Mandl, C., Kunz, C., Harrison, S. C., The envelope glycoprotein from tick-borne encephalitis virus at 2 resolution (1995) Nature, 375, pp. 291-298
White, S. H., Wimley, W. C., Hydrophobic interactions of peptides with membrane interfaces (1998) Biochim. Biophys. Acta Rev. Biomembr., 1376, pp. 339-352
Wimley, W. C., White, S. H., Experimentally determined hydrophobicity scale for proteins at membrane interfaces (1996) Nat. Struct. Biol., 3, pp. 842-848
Wimley, W. C., Hristova, K., Ladokhin, A. S., Silvestro, L., Axelsen, P. H., White, S. H., Folding of -sheet membrane proteins: A hydrophobic hexapeptide model (1998) J. Mol. Biol., 277, pp. 1091-1110
Ladokhin, A. S., White, S. H., Folding of amphipathic -helices on membranes: Energetics of helix formation by melittin (1999) J. Mol. Biol., 285, pp. 1363-1369
Segrest, J. P., De Loof, H., Dohlman, J. G., Brouillette, C. G., Anantharamaiah, G. M., Amphipathic helix motif: Classes and properties (1990) Proteins Struct. Funct. Bioinforma., 8, pp. 103-117
Han, X., Tamm, L. K., PH-dependent self-association of influenza hemagglutinin fusion peptides in lipid bilayers (2000) J. Mol. Biol., 304, pp. 953-965
S ez-Ciri n, A., Nieva, J. L., Conformational transitions of membrane-bound HIV-1 fusion peptide (2002) Biochim. Biophys. Acta Biomembr., 1564, pp. 57-65
Tamm, L. K., Han, X., Li, Y., Lai, A. L., Structure and function of membrane fusion peptides (2002) Biopolym. Pept. Sci. Sect., 66, pp. 249-260
Lai, A. L., Moorthy, A. E., Li, Y., Tamm, L. K., Fusion activity of HIV gp41 fusion domain is related to its secondary structure and depth of membrane insertion in a cholesterol-dependent fashion (2012) J. Mol. Biol., 418, pp. 3-15
Kozlov, M. M., McMahon, H. T., Chernomordik, L. V., Protein-driven membrane stresses in fusion and fission (2010) Trends Biochem. Sci., 35, pp. 699-706
Peisajovich, S. G., Samuel, O., Shai, Y., Paramyxovirus F1 protein has two fusion peptides: Implications for the mechanism of membrane fusion (2000) J. Mol. Biol., 296, pp. 1353-1365
Perez-Berna, A. J., Guillen, J., Moreno, M. R., Bernabeu, A., Pabst, G., Laggner, P., Villalain, J., Identification of the membrane-active regions of hepatitis C virus p7 protein: Biophysical characterization of the loop region (2008) J. Biol. Chem., 283, pp. 8089-8101
Xu, Y., Rahman, N. A., Othman, R. B., Hu, P., Huang, M., Computational identification of self-inhibitory peptides from envelope proteins (2012) Proteins, 80, pp. 2154-2168
Chang, D. K., Cheng, S. F., Lin, C. H., Kantchev, E. B., Wu, C. W., Self-association of glutamic acid-rich fusion peptide analogs of influenza hemagglutinin in the membrane-mimic environments: Effects of positional difference of glutamic acids on side chain ionization constant and intra- and inter-peptide interactions deduced from NMR and gel electrophoresis measurements (2005) Biochim. Biophys. Acta, 1712, pp. 37-51
Lau, W. L., Ege, D. S., Lear, J. D., Hammer, D. A., Degrado, W. F., Oligomerization of fusogenic peptides promotes membrane fusion by enhancing membrane destabilization (2004) Biophys. J., 86, pp. 272-284
Forssmann, W. G., The, Y. H., Stoll, M., Adermann, K., Albrecht, U., Tillmann, H. C., Barlos, K., Schmidt, R. E., Short-term monotherapy in HIV-infected patients with a virus entry inhibitor against the gp41 fusion peptide (2010) Sci. Transl. Med., 2, p. 63re63
M nch, J., St ndker, L., Adermann, K., Schulz, A., Schindler, M., Chinnadurai, R., P hlmann, S., Kirchhoff, F., Discovery and optimization of a natural HIV-1 entry inhibitor targeting the gp41 fusion peptide (2007) Cell, 129, pp. 263-275
Torchilin, V. P., Multifunctional nanocarriers (2006) Adv. Drug Deliv. Rev., 58, pp. 1532-1555
Bareford, L. M., Swaan, P. W., Endocytic mechanisms for targeted drug delivery (2007) Adv. Drug Deliv. Rev., 59, pp. 748-758
Almeida, P. F., Membrane-active peptides: Binding, translocation, and flux in lipid vesicles (2014) Biochim. Biophys. Acta, 1838, pp. 2216-2227
Viv s, E., Brodin, P., Lebleu, B., Truncated HIV-1 Tat protein basic domain rapidly translocates through the plasma membrane (1997) J. Biol. Chem., 272, pp. 16010-16017
Angeles-Boza, A. M., Erazo-Oliveras, A., Lee, Y. -J., Pellois, J. -P., Generation of endosomolytic reagents by branching of cell-penetrating peptides (2010) Bioconjug. Chem., 21, pp. 2164-2167
Morris, M. C., Chaloin, L., Mery, J., Heitz, F., Divita, G., A novel potent strategy for gene delivery using a single peptide vector as a carrier (1999) Nucleic Acids Res., 27, pp. 3510-3517
Morris, M. C., Vidal, P., Chaloin, L., Heitz, F., Divita, G., A new peptide vector for efficient delivery of oligonucleotides into mammalian cells (1997) Nucleic Acids Res., 25, pp. 2730-2736
Gallaher, W. R., Detection of a fusion peptide sequence in the transmembrane protein of human immunodeficiency virus (1987) Cell, 50, pp. 327-328
Delboy, M. G., Patterson, J. L., Hollander, A. M., Nicola, A. V., Nectin-2-mediated entry of a syncytial strain of herpes simplex virus via pH-independent fusion with the plasma membrane of Chinese hamster ovary cells (2006) Virol. J., 3, p. 105
Roller, D. G., Dollery, S. J., Doyle, J. L., Nicola, A. V., Structure-function analysis of herpes simplex virus glycoprotein B with fusion-from-without activity (2008) Virology, 382, pp. 207-216
Milne, R. S., Nicola, A. V., Whitbeck, J. C., Eisenberg, R. J., Cohen, G. H., Glycoprotein D receptor-dependent, low-pH-independent endocytic entry of herpes simplex virus type 1 (2005) J. Virol., 79, pp. 6655-6663
Connolly, S. A., Jackson, J. O., Jardetzky, T. S., Longnecker, R., Fusing structure and function: A structural view of the herpesvirus entry machinery (2011) Nat. Rev. Microbiol., 9, pp. 369-381
Chowdary, T. K., Cairns, T. M., Atanasiu, D., Cohen, G. H., Eisenberg, R. J., Heldwein, E. E., Crystal structure of the conserved herpesvirus fusion regulator complex gH-gL (2010) Nat. Struct. Mol. Biol., 17, pp. 882-888
Heldwein, E. E., Lou, H., Bender, F. C., Cohen, G. H., Eisenberg, R. J., Harrison, S. C., Crystal structure of glycoprotein B from herpes simplex virus 1 (2006) Science, 313, pp. 217-220
Connolly, S. A., Longnecker, R., Residues within the C-terminal arm of the herpes simplex virus 1 glycoprotein B ectodomain contribute to its refolding during the fusion step of virus entry (2012) J. Virol., 86, pp. 6386-6393
Tu, Y., Kim, J. S., A fusogenic segment of glycoprotein H from herpes simplex virus enhances transfection efficiency of cationic liposomes (2008) J. Gene Med., 10, pp. 646-654
Carberry, T. P., Tarallo, R., Falanga, A., Finamore, E., Galdiero, M., Weck, M., Galdiero, S., Dendrimer functionalization with a membrane-interacting domain of herpes simplex virus type 1: Towards intracellular delivery (2012) Chemistry, 18, pp. 13678-13685
Medintz, I. L., Pons, T., Delehanty, J. B., Susumu, K., Brunel, F. M., Dawson, P. E., Mattoussi, H., Intracellular delivery of quantum dot-protein cargos mediated by cell penetrating peptides (2008) Bioconjug. Chem., 19, pp. 1785-1795
Lee, H., Kim, I. K., Park, T. G., Intracellular trafficking and unpacking of siRNA/quantum dot-PEI complexes modified with and without cell penetrating peptide: Confocal and flow cytometric FRET analysis (2010) Bioconjug. Chem., 21, pp. 289-295
Delehanty, J. B., Bradburne, C. E., Susumu, K., Boeneman, K., Mei, B. C., Farrell, D., Blanco-Canosa, J. B., Medintz, I. L., Spatiotemporal multicolor labeling of individual cells using peptide-functionalized quantum dots and mixed delivery techniques (2011) J. Am. Chem. Soc., 133, pp. 10482-10489
Newkome, G. R., Moorefield, C. N., V gtle, F., (2001) Dendrimers and Dendrons: Concepts, Synthesis, Applications, , Wiley-VCH Weinheim
Lee, C. C., Mackay, J. A., Fr chet, J. M. J., Szoka, F. C., Designing dendrimers for biological applications (2005) Nat. Biotechnol., 23, pp. 1517-1526
Gillies, E. R., Frechet, J. M., Dendrimers and dendritic polymers in drug delivery (2005) Drug Discov. Today, 10, pp. 35-43
Seib, F. P., Jones, A. T., Duncan, R., Comparison of the endocytic properties of linear and branched PEIs, and cationic PAMAM dendrimers in B16f10 melanoma cells (2007) J. Control. Release, 117, pp. 291-300
Lu, C. T., Zhao, Y. Z., Wong, H. L., Cai, J., Peng, L., Tian, X. Q., Current approaches to enhance CNS delivery of drugs across the brain barriers (2014) Int. J. Nanomedicine, 9, pp. 2241-2257
Abbott, N. J., Ronnback, L., Hansson, E., Astrocyte-endothelial interactions at the blood-brain barrier (2006) Nat. Rev. Neurosci., 7, pp. 41-53
Mahajan, S. D., Law, W. C., Aalinkeel, R., Reynolds, J., Nair, B. B., Yong, K. T., Roy, I., Schwartz, S. A., Nanoparticle-mediated targeted delivery of antiretrovirals to the brain (2012) Methods Enzymol., 509, pp. 41-60
Jain, K. K., Nanobiotechnology-based strategies for crossing the blood-brain barrier (2012) Nanomedicine (Lond.), 7, pp. 1225-1233
Orive, G., Ali, O. A., Anitua, E., Pedraz, J. L., Emerich, D. F., Biomaterial-based technologies for brain anti-cancer therapeutics and imaging (2010) Biochim. Biophys. Acta, 1806, pp. 96-107
Borlongan, C. V., Emerich, D. F., Facilitation of drug entry into the CNS via transient permeation of blood brain barrier: Laboratory and preliminary clinical evidence from bradykinin receptor agonist, Cereport (2003) Brain Res. Bull., 60, pp. 297-306
Patel, M. M., Goyal, B. R., Bhadada, S. V., Bhatt, J. S., Amin, A. F., Getting into the brain: Approaches to enhance brain drug delivery (2009) CNS Drugs, 23, pp. 35-58
Bba-Gen Subjects (ISSN: 0925-4439, 0006-3002, 1570-9639), 2015 Jan; 1848(PA): 16-25.
Export to BibTeX Export to EndNote
Paper type: Journal Article, Review,
Impact factor: 5.158, 5-year impact factor: 5.36
Url: http://www.scopus.com/inward/record.url?eid=2-s2.0-84908193841&partnerID=40&md5=90b30034e2cbfaad63fa46111e4be207
Keywords: Delivery, Fusion, Hydrophobicity, Membranotropic Peptide, Viral Inhibition, Antivirus Agent, Doxorubicin, Liposome, Nanoparticle, Polystyrene, Protein Gh625, Unclassified Drug, Virus Fusion Protein, Virus Protein, Bilayer Membrane, Blood Brain Barrier, Cell Membrane Transport, Drug Delivery System, Drug Design, Herpes Simplex Virus 1, Human, In Vitro Study, In Vivo Study, Molecular Mechanics, Nonhuman, Review, Virus Entry, Virus Inhibition, Amino Acid Sequence, Cell Membrane Metabolism Virology, Herpes Simplex Metabolism Virology, Herpesvirus 1, Human Metabolism Physiology, Host-Pathogen Interactions, Models, Molecular Sequence Data, Peptides Chemistry Metabolism, Protein Conformation, Viral Envelope Proteins Chemistry Metabolism, Gh625 Peptide, Herpes Simplex Virus Type I, Virus Envelope Protein, Chemical Structure, Host Pathogen Interaction, Molecular Genetics,
Affiliations:
*** IBB - CNR ***
Department of Pharmacy, University of Naples Federico II, Via Mezzocannone 16Naples, Italy
DFM Scarl, University of Naples Federico II, Via Mezzocannone 16Naples, Italy
Department of Experimental Medicine, II University of Naples, Via De Crecchio 7Naples, Italy
References:
Craik, D.J., Fairlie, D.P., Liras, S., Price, D., The future of peptide-based drugs (2013) Chem. Biol. Drug Des., 81, pp. 136-14
Vlieghe, P., Lisowski, V., Martinez, J., Khrestchatisky, M., Synthetic therapeutic peptides: Science and market (2010) Drug Discov. Today, 15, pp. 40-56
Sato, A.K., Viswanathan, M., Kent, R.B., Wood, C.R., Therapeutic peptides: Technological advances driving peptides into development (2006) Curr. Opin. Biotechnol., 17, pp. 638-642
Yau, W.M., Wimley, W.C., Gawrisch, K., White, S.H., The preference of tryptophan for membrane interfaces (1998) Biochemistry, 37, pp. 14713-14718
Harris, F., Wallace, J., Phoenix, D.A., Use of hydrophobic moment plot methodology to aid the identification of oblique orientated α-helices (2000) Mol. Membr. Biol., 17, pp. 201-207
Joanne, P., Nicolas, P., El Amri, C., Antimicrobial peptides and viral fusion peptides: How different they are? (2009) Protein Pept. Lett., 16, pp. 743-750
Cruz, J., Ortiz, C., Guzman, F., Fernandez-Lafuente, R., Torres, R., Antimicrobial peptides: Promising compounds against pathogenic microorganisms (2014) Curr. Med. Chem., 21, pp. 2299-2321
Falanga, A., Cantisani, M., Pedone, C., Galdiero, S., Membrane fusion and fission: Enveloped viruses (2009) Protein Pept. Lett., 16, pp. 751-759
Wang, F., Wang, Y., Zhang, X., Zhang, W., Guo, S., Jin, F., Recent progress of cell-penetrating peptides as new carriers for intracellular cargo delivery (2014) J. Control. Release, 174, pp. 126-136
Harrison, S.C., Mechanism of membrane fusion by viral envelope proteins (2005) Adv. Virus Res., 64, pp. 231-261
Harrison, S.C., Viral membrane fusion (2008) Nat. Struct. Mol. Biol., 15, pp. 690-698
Wilson, I.A., Skehel, J.J., Wiley, D.C., Structure of the haemagglutinin membrane glycoprotein of influenza virus at 3 A resolution (1981) Nature, 289, pp. 366-373
Fass, D., Harrison, S.C., Kim, P.S., Retrovirus envelope domain at 1.7 angstrom resolution (1996) Nat. Struct. Biol., 3, pp. 465-469
Weissenhorn, W., Carfi, A., Lee, K.H., Skehel, J.J., Wiley, D.C., Crystal structure of the Ebola virus membrane fusion subunit, GP2, from the envelope glycoprotein ectodomain (1998) Mol. Cell, 2, pp. 605-616
Yin, H.S., Wen, X., Paterson, R.G., Lamb, R.A., Jardetzky, T.S., Structure of the parainfluenza virus 5 F protein in its metastable, prefusion conformation (2006) Nature, 439, pp. 38-44
Xu, Y., Liu, Y., Lou, Z., Qin, L., Li, X., Bai, Z., Pang, H., Rao, Z., Structural basis for coronavirus-mediated membrane fusion. Crystal structure of mouse hepatitis virus spike protein fusion core (2004) J. Biol. Chem., 279, pp. 30514-30522
Rey, F.A., Heinz, F.X., Mandl, C., Kunz, C., Harrison, S.C., The envelope glycoprotein from tick-borne encephalitis virus at 2 Å resolution (1995) Nature, 375, pp. 291-298
Lescar, J., Roussel, A., Wien, M.W., Navaza, J., Fuller, S.D., Wengler, G., Rey, F.A., The fusion glycoprotein shell of Semliki Forest virus: An icosahedral assembly primed for fusogenic activation at endosomal pH (2001) Cell, 105, pp. 137-148
Backovic, M., Jardetzky, T., Class III viral membrane fusion proteins (2011) Cell Fusion in Health and Disease, pp. 91-101. , T. Dittmar, K.S. Zänker, Springer Netherlands
White, S.H., Wimley, W.C., Hydrophobic interactions of peptides with membrane interfaces (1998) Biochim. Biophys. Acta Rev. Biomembr., 1376, pp. 339-352
Wimley, W.C., White, S.H., Experimentally determined hydrophobicity scale for proteins at membrane interfaces (1996) Nat. Struct. Biol., 3, pp. 842-848
Wimley, W.C., Hristova, K., Ladokhin, A.S., Silvestro, L., Axelsen, P.H., White, S.H., Folding of β-sheet membrane proteins: A hydrophobic hexapeptide model (1998) J. Mol. Biol., 277, pp. 1091-1110
Ladokhin, A.S., White, S.H., Folding of amphipathic α-helices on membranes: Energetics of helix formation by melittin (1999) J. Mol. Biol., 285, pp. 1363-1369
Segrest, J.P., De Loof, H., Dohlman, J.G., Brouillette, C.G., Anantharamaiah, G.M., Amphipathic helix motif: Classes and properties (1990) Proteins Struct. Funct. Bioinforma., 8, pp. 103-117
Han, X., Tamm, L.K., PH-dependent self-association of influenza hemagglutinin fusion peptides in lipid bilayers (2000) J. Mol. Biol., 304, pp. 953-965
Sáez-Cirión, A., Nieva, J.L., Conformational transitions of membrane-bound HIV-1 fusion peptide (2002) Biochim. Biophys. Acta Biomembr., 1564, pp. 57-65
Han, X., Bushweller, J.H., Cafiso, D.S., Tamm, L.K., Membrane structure and fusion-triggering conformational change of the fusion domain from influenza hemagglutinin (2001) Nat. Struct. Biol., 8, pp. 715-720
Tamm, L.K., Han, X., Li, Y., Lai, A.L., Structure and function of membrane fusion peptides (2002) Biopolym. Pept. Sci. Sect., 66, pp. 249-260
Agopian, A., Castano, S., Structure and orientation study of Ebola fusion peptide inserted in lipid membrane models (2014) Biochim. Biophys. Acta Biomembr., 1838, pp. 117-126
Apellaniz, B., Huarte, N., Largo, E., Nieva, J.L., The three lives of viral fusion peptides (2014) Chem. Phys. Lipids, 181, pp. 40-55
Lai, A.L., Moorthy, A.E., Li, Y., Tamm, L.K., Fusion activity of HIV gp41 fusion domain is related to its secondary structure and depth of membrane insertion in a cholesterol-dependent fashion (2012) J. Mol. Biol., 418, pp. 3-15
Larsson, P., Kasson, P.M., Lipid tail protrusion in simulations predicts fusogenic activity of influenza fusion peptide mutants and conformational models (2013) PLoS Comput. Biol., 9, p. 1002950
Kozlov, M.M., McMahon, H.T., Chernomordik, L.V., Protein-driven membrane stresses in fusion and fission (2010) Trends Biochem. Sci., 35, pp. 699-706
Peisajovich, S.G., Samuel, O., Shai, Y., Paramyxovirus F1 protein has two fusion peptides: Implications for the mechanism of membrane fusion (2000) J. Mol. Biol., 296, pp. 1353-1365
Perez-Berna, A.J., Guillen, J., Moreno, M.R., Bernabeu, A., Pabst, G., Laggner, P., Villalain, J., Identification of the membrane-active regions of hepatitis C virus p7 protein: Biophysical characterization of the loop region (2008) J. Biol. Chem., 283, pp. 8089-8101
Nemesio, H., Palomares-Jerez, F., Villalain, J., The membrane-active regions of the dengue virus proteins C and e (2011) Biochim. Biophys. Acta, 1808, pp. 2390-2402
Galdiero, S., Falanga, A., Vitiello, M., Browne, H., Pedone, C., Galdiero, M., Fusogenic domains in herpes simplex virus type 1 glycoprotein H (2005) J. Biol. Chem., 280, pp. 28632-28643
Galdiero, S., Vitiello, M., D'Isanto, M., Falanga, A., Cantisani, M., Browne, H., Pedone, C., Galdiero, M., The identification and characterization of fusogenic domains in herpes virus glycoprotein B molecules (2008) Chembiochem, 9, pp. 758-767
Lorizate, M., Huarte, N., Saez-Cirion, A., Nieva, J.L., Interfacial pre-transmembrane domains in viral proteins promoting membrane fusion and fission (2008) Biochim. Biophys. Acta, 1778, pp. 1624-1639
D'Errico, G., D'Ursi, A.M., Marsh, D., Interaction of a peptide derived from glycoprotein gp36 of feline immunodeficiency virus and its lipoylated analogue with phospholipid membranes (2008) Biochemistry, 47, pp. 5317-5327
Badani, H., Garry, R.F., Wimley, W.C., Peptide entry inhibitors of enveloped viruses: The importance of interfacial hydrophobicity (2014) Biochim. Biophys. Acta Biomembr, 1838, pp. 2180-2197
Rapaport, D., Ovadia, M., Shai, Y., A synthetic peptide corresponding to a conserved heptad repeat domain is a potent inhibitor of Sendai virus-cell fusion: An emerging similarity with functional domains of other viruses (1995) EMBO J., 14, pp. 5524-5531
Xu, Y., Rahman, N.A., Othman, R.B., Hu, P., Huang, M., Computational identification of self-inhibitory peptides from envelope proteins (2012) Proteins, 80, pp. 2154-2168
Chang, D.K., Cheng, S.F., Lin, C.H., Kantchev, E.B., Wu, C.W., Self-association of glutamic acid-rich fusion peptide analogs of influenza hemagglutinin in the membrane-mimic environments: Effects of positional difference of glutamic acids on side chain ionization constant and intra- and inter-peptide interactions deduced from NMR and gel electrophoresis measurements (2005) Biochim. Biophys. Acta, 1712, pp. 37-51
Lau, W.L., Ege, D.S., Lear, J.D., Hammer, D.A., Degrado, W.F., Oligomerization of fusogenic peptides promotes membrane fusion by enhancing membrane destabilization (2004) Biophys. J., 86, pp. 272-284
Kliger, Y., Aharoni, A., Rapaport, D., Jones, P., Blumenthal, R., Shai, Y., Fusion peptides derived from the HIV type 1 glycoprotein 41 associate within phospholipid membranes and inhibit cell-cell fusion. Structure-function study (1997) J. Biol. Chem., 272, pp. 13496-13505
Pritsker, M., Jones, P., Blumenthal, R., Shai, Y., A synthetic all D-amino acid peptide corresponding to the N-terminal sequence of HIV-1 gp41 recognizes the wild-type fusion peptide in the membrane and inhibits HIV-1 envelope glycoprotein-mediated cell fusion (1998) Proc. Natl. Acad. Sci. U. S. A., 95, pp. 7287-7292
Li, Y., Han, X., Tamm, L.K., Thermodynamics of fusion peptide-membrane interactions (2003) Biochemistry, 42, pp. 7245-7251
Forssmann, W.G., The, Y.H., Stoll, M., Adermann, K., Albrecht, U., Tillmann, H.C., Barlos, K., Schmidt, R.E., Short-term monotherapy in HIV-infected patients with a virus entry inhibitor against the gp41 fusion peptide (2010) Sci. Transl. Med., 2, p. 63re63
Münch, J., Ständker, L., Adermann, K., Schulz, A., Schindler, M., Chinnadurai, R., Pöhlmann, S., Kirchhoff, F., Discovery and optimization of a natural HIV-1 entry inhibitor targeting the gp41 fusion peptide (2007) Cell, 129, pp. 263-275
Torchilin, V.P., Multifunctional nanocarriers (2006) Adv. Drug Deliv. Rev., 58, pp. 1532-1555
Bareford, L.M., Swaan, P.W., Endocytic mechanisms for targeted drug delivery (2007) Adv. Drug Deliv. Rev., 59, pp. 748-758
He, J., Kauffman, W.B., Fuselier, T., Naveen, S.K., Voss, T.G., Hristova, K., Wimley, W.C., Direct cytosolic delivery of polar cargo to cells by spontaneous membrane-translocating peptides (2013) J. Biol. Chem., 288, pp. 29974-29986
Guarnieri, D., Falanga, A., Muscetti, O., Tarallo, R., Fusco, S., Galdiero, M., Galdiero, S., Netti, P.A., Shuttle-mediated nanoparticle delivery to the blood-brain barrier (2013) Small, 9, pp. 853-862
Almeida, P.F., Membrane-active peptides: Binding, translocation, and flux in lipid vesicles (2014) Biochim. Biophys. Acta, 1838, pp. 2216-2227
Heitz, F., Morris, M.C., Divita, G., Twenty years of cell-penetrating peptides: From molecular mechanisms to therapeutics (2009) Br. J. Pharmacol., 157, pp. 195-206
Vivès, E., Brodin, P., Lebleu, B., Truncated HIV-1 Tat protein basic domain rapidly translocates through the plasma membrane (1997) J. Biol. Chem., 272, pp. 16010-16017
Angeles-Boza, A.M., Erazo-Oliveras, A., Lee, Y.-J., Pellois, J.-P., Generation of endosomolytic reagents by branching of cell-penetrating peptides (2010) Bioconjug. Chem., 21, pp. 2164-2167
Morris, M.C., Chaloin, L., Mery, J., Heitz, F., Divita, G., A novel potent strategy for gene delivery using a single peptide vector as a carrier (1999) Nucleic Acids Res., 27, pp. 3510-3517
Morris, M.C., Vidal, P., Chaloin, L., Heitz, F., Divita, G., A new peptide vector for efficient delivery of oligonucleotides into mammalian cells (1997) Nucleic Acids Res., 25, pp. 2730-2736
Gallaher, W.R., Detection of a fusion peptide sequence in the transmembrane protein of human immunodeficiency virus (1987) Cell, 50, pp. 327-328
Kalderon, D., Smith, A.E., In vitro mutagenesis of a putative DNA binding domain of SV40 large-T (1984) Virology, 139, pp. 109-137
Delboy, M.G., Patterson, J.L., Hollander, A.M., Nicola, A.V., Nectin-2-mediated entry of a syncytial strain of herpes simplex virus via pH-independent fusion with the plasma membrane of Chinese hamster ovary cells (2006) Virol. J., 3, p. 105
Roller, D.G., Dollery, S.J., Doyle, J.L., Nicola, A.V., Structure-function analysis of herpes simplex virus glycoprotein B with fusion-from-without activity (2008) Virology, 382, pp. 207-216
Arii, J., Uema, M., Morimoto, T., Sagara, H., Akashi, H., Ono, E., Arase, H., Kawaguchi, Y., Entry of herpes simplex virus 1 and other alphaherpesviruses via the paired immunoglobulin-like type 2 receptor alpha (2009) J. Virol., 83, pp. 4520-4527
Milne, R.S., Nicola, A.V., Whitbeck, J.C., Eisenberg, R.J., Cohen, G.H., Glycoprotein D receptor-dependent, low-pH-independent endocytic entry of herpes simplex virus type 1 (2005) J. Virol., 79, pp. 6655-6663
Connolly, S.A., Jackson, J.O., Jardetzky, T.S., Longnecker, R., Fusing structure and function: A structural view of the herpesvirus entry machinery (2011) Nat. Rev. Microbiol., 9, pp. 369-381
Turner, A., Bruun, B., Minson, T., Browne, H., Glycoproteins gB, gD, and gHgL of herpes simplex virus type 1 are necessary and sufficient to mediate membrane fusion in a Cos cell transfection system (1998) J. Virol., 72, pp. 873-875
Farnsworth, A., Wisner, T.W., Webb, M., Roller, R., Cohen, G., Eisenberg, R., Johnson, D.C., Herpes simplex virus glycoproteins gB and gH function in fusion between the virion envelope and the outer nuclear membrane (2007) Proc. Natl. Acad. Sci. U. S. A., 104, pp. 10187-10192
Falanga, A., Tarallo, R., Vitiello, G., Vitiello, M., Perillo, E., Cantisani, M., D'Errico, G., Galdiero, S., Biophysical characterization and membrane interaction of the two fusion loops of glycoprotein B from herpes simplex type i virus (2012) PLoS One, 7, p. 32186
Galdiero, S., Russo, L., Falanga, A., Cantisani, M., Vitiello, M., Fattorusso, R., Malgieri, G., Isernia, C., Structure and orientation of the gH625-644 membrane interacting region of herpes simplex virus type 1 in a membrane mimetic system (2012) Biochemistry, 51, pp. 3121-3128
Chowdary, T.K., Cairns, T.M., Atanasiu, D., Cohen, G.H., Eisenberg, R.J., Heldwein, E.E., Crystal structure of the conserved herpesvirus fusion regulator complex gH-gL (2010) Nat. Struct. Mol. Biol., 17, pp. 882-888
Matsuura, H., Kirschner, A.N., Longnecker, R., Jardetzky, T.S., Crystal structure of the Epstein-Barr virus (EBV) glycoprotein H/glycoprotein L (gH/gL) complex (2010) Proc. Natl. Acad. Sci. U. S. A., 107, pp. 22641-22646
Heldwein, E.E., Lou, H., Bender, F.C., Cohen, G.H., Eisenberg, R.J., Harrison, S.C., Crystal structure of glycoprotein B from herpes simplex virus 1 (2006) Science, 313, pp. 217-220
Connolly, S.A., Longnecker, R., Residues within the C-terminal arm of the herpes simplex virus 1 glycoprotein B ectodomain contribute to its refolding during the fusion step of virus entry (2012) J. Virol., 86, pp. 6386-6393
Cantisani, M., Falanga, A., Incoronato, N., Russo, L., De Simone, A., Morelli, G., Berisio, R., Galdiero, S., Conformational modifications of gB from herpes simplex virus type 1 analyzed by synthetic peptides (2013) J. Med. Chem., 56, pp. 8366-8376
Backovic, M., Longnecker, R., Jardetzky, T.S., Structure of a trimeric variant of the Epstein-Barr virus glycoprotein B (2009) Proc. Natl. Acad. Sci. U. S. A., 106, pp. 2880-2885
Roche, S., Bressanelli, S., Rey, F.A., Gaudin, Y., Crystal structure of the low-pH form of the vesicular stomatitis virus glycoprotein G (2006) Science, 313, pp. 187-191
Kadlec, J., Loureiro, S., Abrescia, N.G., Stuart, D.I., Jones, I.M., The postfusion structure of baculovirus gp64 supports a unified view of viral fusion machines (2008) Nat. Struct. Mol. Biol., 15, pp. 1024-1030
Akkarawongsa, R., Pocaro, N.E., Case, G., Kolb, A.W., Brandt, C.R., Multiple peptides homologous to herpes simplex virus type 1 glycoprotein B inhibit viral infection (2009) Antimicrob. Agents Chemother., 53, pp. 987-996
Vitiello, G., Falanga, A., Galdiero, M., Marsh, D., Galdiero, S., D'Errico, G., Lipid composition modulates the interaction of peptides deriving from herpes simplex virus type i glycoproteins B and H with biomembranes (2011) Biochim. Biophys. Acta, 1808, pp. 2517-2526
Krishnan, A., Verma, S.K., Mani, P., Gupta, R., Kundu, S., Sarkar, D.P., A histidine switch in hemagglutinin-neuraminidase triggers paramyxovirus-cell membrane fusion (2009) J. Virol., 83, pp. 1727-1741
Chanel-Vos, C., Kielian, M., A conserved histidine in the ij loop of the Semliki Forest virus E1 protein plays an important role in membrane fusion (2004) J. Virol., 78, pp. 13543-13552
Tarallo, R., Carberry, T.P., Falanga, A., Vitiello, M., Galdiero, S., Galdiero, M., Weck, M., Dendrimers functionalized with membrane-interacting peptides for viral inhibition (2013) Int. J. Nanomedicine, 8, pp. 521-534
Tu, Y., Kim, J.S., A fusogenic segment of glycoprotein H from herpes simplex virus enhances transfection efficiency of cationic liposomes (2008) J. Gene Med., 10, pp. 646-654
Tarallo, R., Accardo, A., Falanga, A., Guarnieri, D., Vitiello, G., Netti, P., D'Errico, G., Galdiero, S., Clickable functionalization of liposomes with the gH625 peptide from Herpes simplex virus type i for intracellular drug delivery (2011) Chemistry, 17, pp. 12659-12668
Carberry, T.P., Tarallo, R., Falanga, A., Finamore, E., Galdiero, M., Weck, M., Galdiero, S., Dendrimer functionalization with a membrane-interacting domain of herpes simplex virus type 1: Towards intracellular delivery (2012) Chemistry, 18, pp. 13678-13685
Smaldone, G., Falanga, A., Capasso, D., Guarnieri, D., Correale, S., Galdiero, M., Netti, P.A., Pedone, E., GH625 is a viral derived peptide for effective delivery of intrinsically disordered proteins (2013) Int. J. Nanomedicine, 8, pp. 2555-2565
Pinaud, F., Clarke, S., Sittner, A., Dahan, M., Probing cellular events, one quantum dot at a time (2010) Nat. Methods, 7, pp. 275-285
Medintz, I.L., Pons, T., Delehanty, J.B., Susumu, K., Brunel, F.M., Dawson, P.E., Mattoussi, H., Intracellular delivery of quantum dot-protein cargos mediated by cell penetrating peptides (2008) Bioconjug. Chem., 19, pp. 1785-1795
Lee, H., Kim, I.K., Park, T.G., Intracellular trafficking and unpacking of siRNA/quantum dot-PEI complexes modified with and without cell penetrating peptide: Confocal and flow cytometric FRET analysis (2010) Bioconjug. Chem., 21, pp. 289-295
Delehanty, J.B., Bradburne, C.E., Susumu, K., Boeneman, K., Mei, B.C., Farrell, D., Blanco-Canosa, J.B., Medintz, I.L., Spatiotemporal multicolor labeling of individual cells using peptide-functionalized quantum dots and mixed delivery techniques (2011) J. Am. Chem. Soc., 133, pp. 10482-10489
Cukierman, E., Khan, D.R., The benefits and challenges associated with the use of drug delivery systems in cancer therapy (2010) Biochem. Pharmacol., 80, pp. 762-770
Newkome, G.R., Moorefield, C.N., Vögtle, F., (2001) Dendrimers and Dendrons: Concepts, Synthesis, Applications, , Wiley-VCH Weinheim
Lee, C.C., Mackay, J.A., Fréchet, J.M.J., Szoka, F.C., Designing dendrimers for biological applications (2005) Nat. Biotechnol., 23, pp. 1517-1526
Gillies, E.R., Frechet, J.M., Dendrimers and dendritic polymers in drug delivery (2005) Drug Discov. Today, 10, pp. 35-43
Gunaseelan, S., Gunaseelan, K., Deshmukh, M., Zhang, X., Sinko, P.J., Surface modifications of nanocarriers for effective intracellular delivery of anti-HIV drugs (2010) Adv. Drug Deliv. Rev., 62, pp. 518-531
Najlah, M., D'Emanuele, A., Crossing cellular barriers using dendrimer nanotechnologies (2006) Curr. Opin. Pharmacol., 6, pp. 522-527
Seib, F.P., Jones, A.T., Duncan, R., Comparison of the endocytic properties of linear and branched PEIs, and cationic PAMAM dendrimers in B16f10 melanoma cells (2007) J. Control. Release, 117, pp. 291-300
Kang, H., Delong, R., Fisher, M.H., Juliano, R.L., Tat-conjugated PAMAM dendrimers as delivery agents for antisense and siRNA oligonucleotides (2005) Pharm. Res., 22, pp. 2099-2106
Lu, C.T., Zhao, Y.Z., Wong, H.L., Cai, J., Peng, L., Tian, X.Q., Current approaches to enhance CNS delivery of drugs across the brain barriers (2014) Int. J. Nanomedicine, 9, pp. 2241-2257
Abbott, N.J., Ronnback, L., Hansson, E., Astrocyte-endothelial interactions at the blood-brain barrier (2006) Nat. Rev. Neurosci., 7, pp. 41-53
Mahajan, S.D., Law, W.C., Aalinkeel, R., Reynolds, J., Nair, B.B., Yong, K.T., Roy, I., Schwartz, S.A., Nanoparticle-mediated targeted delivery of antiretrovirals to the brain (2012) Methods Enzymol., 509, pp. 41-60
Jain, K.K., Nanobiotechnology-based strategies for crossing the blood-brain barrier (2012) Nanomedicine (Lond.), 7, pp. 1225-1233
Orive, G., Ali, O.A., Anitua, E., Pedraz, J.L., Emerich, D.F., Biomaterial-based technologies for brain anti-cancer therapeutics and imaging (2010) Biochim. Biophys. Acta, 1806, pp. 96-107
Qiao, R., Jia, Q., Huwel, S., Xia, R., Liu, T., Gao, F., Galla, H.J., Gao, M., Receptor-mediated delivery of magnetic nanoparticles across the blood-brain barrier (2012) ACS Nano, 6, pp. 3304-3310
Valiante, S., Falanga, A., Cigliano, L., Iachetta, G., Busiello, R.A., La Marca, V., Galdiero, M., Galdiero, S., (2014) The Peptide gH625 Enters into Neuron and Astrocyte Cell Lines and Crosses the Blood Brain Barrier in Rats, , (submitted for publication)
Fawell, S., Seery, J., Daikh, Y., Moore, C., Chen, L.L., Pepinsky, B., Barsoum, J., Tat-mediated delivery of heterologous proteins into cells (1994) Proc. Natl. Acad. Sci., 91, pp. 664-668
Schutze-Redelmeier, M.P., Gournier, H., Garcia-Pons, F., Moussa, M., Joliot, A.H., Volovitch, M., Prochiantz, A., Lemonnier, F.A., Introduction of exogenous antigens into the MHC class i processing and presentation pathway by Drosophila antennapedia homeodomain primes cytotoxic T cells in vivo (1996) J. Immunol., 157, pp. 650-655
Borlongan, C.V., Emerich, D.F., Facilitation of drug entry into the CNS via transient permeation of blood brain barrier: Laboratory and preliminary clinical evidence from bradykinin receptor agonist, Cereport (2003) Brain Res. Bull., 60, pp. 297-306
Patel, M.M., Goyal, B.R., Bhadada, S.V., Bhatt, J.S., Amin, A.F., Getting into the brain: Approaches to enhance brain drug delivery (2009) CNS Drugs, 23, pp. 35-58
Craik, D. J., Fairlie, D. P., Liras, S., Price, D., The future of peptide-based drugs (2013) Chem. Biol. Drug Des., 81, pp. 136-14
Sato, A. K., Viswanathan, M., Kent, R. B., Wood, C. R., Therapeutic peptides: Technological advances driving peptides into development (2006) Curr. Opin. Biotechnol., 17, pp. 638-642
Yau, W. M., Wimley, W. C., Gawrisch, K., White, S. H., The preference of tryptophan for membrane interfaces (1998) Biochemistry, 37, pp. 14713-14718
Harrison, S. C., Mechanism of membrane fusion by viral envelope proteins (2005) Adv. Virus Res., 64, pp. 231-261
Harrison, S. C., Viral membrane fusion (2008) Nat. Struct. Mol. Biol., 15, pp. 690-698
Wilson, I. A., Skehel, J. J., Wiley, D. C., Structure of the haemagglutinin membrane glycoprotein of influenza virus at 3 A resolution (1981) Nature, 289, pp. 366-373
Yin, H. S., Wen, X., Paterson, R. G., Lamb, R. A., Jardetzky, T. S., Structure of the parainfluenza virus 5 F protein in its metastable, prefusion conformation (2006) Nature, 439, pp. 38-44
Rey, F. A., Heinz, F. X., Mandl, C., Kunz, C., Harrison, S. C., The envelope glycoprotein from tick-borne encephalitis virus at 2 resolution (1995) Nature, 375, pp. 291-298
White, S. H., Wimley, W. C., Hydrophobic interactions of peptides with membrane interfaces (1998) Biochim. Biophys. Acta Rev. Biomembr., 1376, pp. 339-352
Wimley, W. C., White, S. H., Experimentally determined hydrophobicity scale for proteins at membrane interfaces (1996) Nat. Struct. Biol., 3, pp. 842-848
Wimley, W. C., Hristova, K., Ladokhin, A. S., Silvestro, L., Axelsen, P. H., White, S. H., Folding of -sheet membrane proteins: A hydrophobic hexapeptide model (1998) J. Mol. Biol., 277, pp. 1091-1110
Ladokhin, A. S., White, S. H., Folding of amphipathic -helices on membranes: Energetics of helix formation by melittin (1999) J. Mol. Biol., 285, pp. 1363-1369
Segrest, J. P., De Loof, H., Dohlman, J. G., Brouillette, C. G., Anantharamaiah, G. M., Amphipathic helix motif: Classes and properties (1990) Proteins Struct. Funct. Bioinforma., 8, pp. 103-117
Han, X., Tamm, L. K., PH-dependent self-association of influenza hemagglutinin fusion peptides in lipid bilayers (2000) J. Mol. Biol., 304, pp. 953-965
S ez-Ciri n, A., Nieva, J. L., Conformational transitions of membrane-bound HIV-1 fusion peptide (2002) Biochim. Biophys. Acta Biomembr., 1564, pp. 57-65
Tamm, L. K., Han, X., Li, Y., Lai, A. L., Structure and function of membrane fusion peptides (2002) Biopolym. Pept. Sci. Sect., 66, pp. 249-260
Lai, A. L., Moorthy, A. E., Li, Y., Tamm, L. K., Fusion activity of HIV gp41 fusion domain is related to its secondary structure and depth of membrane insertion in a cholesterol-dependent fashion (2012) J. Mol. Biol., 418, pp. 3-15
Kozlov, M. M., McMahon, H. T., Chernomordik, L. V., Protein-driven membrane stresses in fusion and fission (2010) Trends Biochem. Sci., 35, pp. 699-706
Peisajovich, S. G., Samuel, O., Shai, Y., Paramyxovirus F1 protein has two fusion peptides: Implications for the mechanism of membrane fusion (2000) J. Mol. Biol., 296, pp. 1353-1365
Perez-Berna, A. J., Guillen, J., Moreno, M. R., Bernabeu, A., Pabst, G., Laggner, P., Villalain, J., Identification of the membrane-active regions of hepatitis C virus p7 protein: Biophysical characterization of the loop region (2008) J. Biol. Chem., 283, pp. 8089-8101
Xu, Y., Rahman, N. A., Othman, R. B., Hu, P., Huang, M., Computational identification of self-inhibitory peptides from envelope proteins (2012) Proteins, 80, pp. 2154-2168
Chang, D. K., Cheng, S. F., Lin, C. H., Kantchev, E. B., Wu, C. W., Self-association of glutamic acid-rich fusion peptide analogs of influenza hemagglutinin in the membrane-mimic environments: Effects of positional difference of glutamic acids on side chain ionization constant and intra- and inter-peptide interactions deduced from NMR and gel electrophoresis measurements (2005) Biochim. Biophys. Acta, 1712, pp. 37-51
Lau, W. L., Ege, D. S., Lear, J. D., Hammer, D. A., Degrado, W. F., Oligomerization of fusogenic peptides promotes membrane fusion by enhancing membrane destabilization (2004) Biophys. J., 86, pp. 272-284
Forssmann, W. G., The, Y. H., Stoll, M., Adermann, K., Albrecht, U., Tillmann, H. C., Barlos, K., Schmidt, R. E., Short-term monotherapy in HIV-infected patients with a virus entry inhibitor against the gp41 fusion peptide (2010) Sci. Transl. Med., 2, p. 63re63
M nch, J., St ndker, L., Adermann, K., Schulz, A., Schindler, M., Chinnadurai, R., P hlmann, S., Kirchhoff, F., Discovery and optimization of a natural HIV-1 entry inhibitor targeting the gp41 fusion peptide (2007) Cell, 129, pp. 263-275
Torchilin, V. P., Multifunctional nanocarriers (2006) Adv. Drug Deliv. Rev., 58, pp. 1532-1555
Bareford, L. M., Swaan, P. W., Endocytic mechanisms for targeted drug delivery (2007) Adv. Drug Deliv. Rev., 59, pp. 748-758
Almeida, P. F., Membrane-active peptides: Binding, translocation, and flux in lipid vesicles (2014) Biochim. Biophys. Acta, 1838, pp. 2216-2227
Viv s, E., Brodin, P., Lebleu, B., Truncated HIV-1 Tat protein basic domain rapidly translocates through the plasma membrane (1997) J. Biol. Chem., 272, pp. 16010-16017
Angeles-Boza, A. M., Erazo-Oliveras, A., Lee, Y. -J., Pellois, J. -P., Generation of endosomolytic reagents by branching of cell-penetrating peptides (2010) Bioconjug. Chem., 21, pp. 2164-2167
Morris, M. C., Chaloin, L., Mery, J., Heitz, F., Divita, G., A novel potent strategy for gene delivery using a single peptide vector as a carrier (1999) Nucleic Acids Res., 27, pp. 3510-3517
Morris, M. C., Vidal, P., Chaloin, L., Heitz, F., Divita, G., A new peptide vector for efficient delivery of oligonucleotides into mammalian cells (1997) Nucleic Acids Res., 25, pp. 2730-2736
Gallaher, W. R., Detection of a fusion peptide sequence in the transmembrane protein of human immunodeficiency virus (1987) Cell, 50, pp. 327-328
Delboy, M. G., Patterson, J. L., Hollander, A. M., Nicola, A. V., Nectin-2-mediated entry of a syncytial strain of herpes simplex virus via pH-independent fusion with the plasma membrane of Chinese hamster ovary cells (2006) Virol. J., 3, p. 105
Roller, D. G., Dollery, S. J., Doyle, J. L., Nicola, A. V., Structure-function analysis of herpes simplex virus glycoprotein B with fusion-from-without activity (2008) Virology, 382, pp. 207-216
Milne, R. S., Nicola, A. V., Whitbeck, J. C., Eisenberg, R. J., Cohen, G. H., Glycoprotein D receptor-dependent, low-pH-independent endocytic entry of herpes simplex virus type 1 (2005) J. Virol., 79, pp. 6655-6663
Connolly, S. A., Jackson, J. O., Jardetzky, T. S., Longnecker, R., Fusing structure and function: A structural view of the herpesvirus entry machinery (2011) Nat. Rev. Microbiol., 9, pp. 369-381
Chowdary, T. K., Cairns, T. M., Atanasiu, D., Cohen, G. H., Eisenberg, R. J., Heldwein, E. E., Crystal structure of the conserved herpesvirus fusion regulator complex gH-gL (2010) Nat. Struct. Mol. Biol., 17, pp. 882-888
Heldwein, E. E., Lou, H., Bender, F. C., Cohen, G. H., Eisenberg, R. J., Harrison, S. C., Crystal structure of glycoprotein B from herpes simplex virus 1 (2006) Science, 313, pp. 217-220
Connolly, S. A., Longnecker, R., Residues within the C-terminal arm of the herpes simplex virus 1 glycoprotein B ectodomain contribute to its refolding during the fusion step of virus entry (2012) J. Virol., 86, pp. 6386-6393
Tu, Y., Kim, J. S., A fusogenic segment of glycoprotein H from herpes simplex virus enhances transfection efficiency of cationic liposomes (2008) J. Gene Med., 10, pp. 646-654
Carberry, T. P., Tarallo, R., Falanga, A., Finamore, E., Galdiero, M., Weck, M., Galdiero, S., Dendrimer functionalization with a membrane-interacting domain of herpes simplex virus type 1: Towards intracellular delivery (2012) Chemistry, 18, pp. 13678-13685
Medintz, I. L., Pons, T., Delehanty, J. B., Susumu, K., Brunel, F. M., Dawson, P. E., Mattoussi, H., Intracellular delivery of quantum dot-protein cargos mediated by cell penetrating peptides (2008) Bioconjug. Chem., 19, pp. 1785-1795
Lee, H., Kim, I. K., Park, T. G., Intracellular trafficking and unpacking of siRNA/quantum dot-PEI complexes modified with and without cell penetrating peptide: Confocal and flow cytometric FRET analysis (2010) Bioconjug. Chem., 21, pp. 289-295
Delehanty, J. B., Bradburne, C. E., Susumu, K., Boeneman, K., Mei, B. C., Farrell, D., Blanco-Canosa, J. B., Medintz, I. L., Spatiotemporal multicolor labeling of individual cells using peptide-functionalized quantum dots and mixed delivery techniques (2011) J. Am. Chem. Soc., 133, pp. 10482-10489
Newkome, G. R., Moorefield, C. N., V gtle, F., (2001) Dendrimers and Dendrons: Concepts, Synthesis, Applications, , Wiley-VCH Weinheim
Lee, C. C., Mackay, J. A., Fr chet, J. M. J., Szoka, F. C., Designing dendrimers for biological applications (2005) Nat. Biotechnol., 23, pp. 1517-1526
Gillies, E. R., Frechet, J. M., Dendrimers and dendritic polymers in drug delivery (2005) Drug Discov. Today, 10, pp. 35-43
Seib, F. P., Jones, A. T., Duncan, R., Comparison of the endocytic properties of linear and branched PEIs, and cationic PAMAM dendrimers in B16f10 melanoma cells (2007) J. Control. Release, 117, pp. 291-300
Lu, C. T., Zhao, Y. Z., Wong, H. L., Cai, J., Peng, L., Tian, X. Q., Current approaches to enhance CNS delivery of drugs across the brain barriers (2014) Int. J. Nanomedicine, 9, pp. 2241-2257
Abbott, N. J., Ronnback, L., Hansson, E., Astrocyte-endothelial interactions at the blood-brain barrier (2006) Nat. Rev. Neurosci., 7, pp. 41-53
Mahajan, S. D., Law, W. C., Aalinkeel, R., Reynolds, J., Nair, B. B., Yong, K. T., Roy, I., Schwartz, S. A., Nanoparticle-mediated targeted delivery of antiretrovirals to the brain (2012) Methods Enzymol., 509, pp. 41-60
Jain, K. K., Nanobiotechnology-based strategies for crossing the blood-brain barrier (2012) Nanomedicine (Lond.), 7, pp. 1225-1233
Orive, G., Ali, O. A., Anitua, E., Pedraz, J. L., Emerich, D. F., Biomaterial-based technologies for brain anti-cancer therapeutics and imaging (2010) Biochim. Biophys. Acta, 1806, pp. 96-107
Borlongan, C. V., Emerich, D. F., Facilitation of drug entry into the CNS via transient permeation of blood brain barrier: Laboratory and preliminary clinical evidence from bradykinin receptor agonist, Cereport (2003) Brain Res. Bull., 60, pp. 297-306
Patel, M. M., Goyal, B. R., Bhadada, S. V., Bhatt, J. S., Amin, A. F., Getting into the brain: Approaches to enhance brain drug delivery (2009) CNS Drugs, 23, pp. 35-58
gH625: A milestone in understanding the many roles of membranotropic peptides
Here, we review the current knowledge about viral derived membranotropic peptides, and we discuss how they may be used for many therapeutic applications. While they have been initially discovered in viral fusion proteins and have been involved in the mechanism of viral entry, it is now clear that their features and their mode of interaction with membrane bilayers can be exploited to design viral inhibitors as well as to favor delivery of cargos across the cell membrane and across the blood-brain barrier. The peptide gH625 has been extensively used for all these purposes and provides a significant contribution to the field. We describe the roles of this sequence in order to close the gap between the many functions that are now emerging for membranotropic peptides. (C) 2014 Elsevier B.V. All rights reserved.
Here, we review the current knowledge about viral derived membranotropic peptides, and we discuss how they may be used for many therapeutic applications. While they have been initially discovered in viral fusion proteins and have been involved in the mechanism of viral entry, it is now clear that their features and their mode of interaction with membrane bilayers can be exploited to design viral inhibitors as well as to favor delivery of cargos across the cell membrane and across the blood-brain barrier. The peptide gH625 has been extensively used for all these purposes and provides a significant contribution to the field. We describe the roles of this sequence in order to close the gap between the many functions that are now emerging for membranotropic peptides. (C) 2014 Elsevier B.V. All rights reserved.
gH625: A milestone in understanding the many roles of membranotropic peptides
No results. |
gH625: A milestone in understanding the many roles of membranotropic peptides
Other filter: ([btitle,keywords] "Hydrophobicity" OR [ ...
Capozza M, Anemone A, Dhakan C, Della Peruta M, Bracesco M, Zullino S, Villano D, Terreno E, Longo DL, Aime S
* GlucoCEST MRI for the Evaluation Response to Chemotherapeutic and Metabolic Treatments in a Murine Triple-Negative Breast Cancer: A Comparison with[(18)F]F-FDG-PET (12 views)
Mol Imaging Biol (ISSN: 1536-1632linking), 2021 Aug 12; N/D: N/D-N/D.
Impact Factor:
View Export to BibTeX Export to EndNote
Cozzolino A, Vergalito F, Tremonte P, Iorizzo M, Lombardi SJ, Sorrentino E, Luongo D, Coppola R, Marco RD, Succi M
* Preliminary Evaluation of the Safety and Probiotic Potential of Akkermansia muciniphila DSM 22959 in Comparison with Lactobacillus rhamnosus GG (172 views)
Microorganisms (ISSN: 2076-2607linking), 2020 Jan 30; 8(2): N/D-N/D.
Impact Factor: 4.167
View Export to BibTeX Export to EndNote
Mercurio V, Cuomo A, Della Pepa R, Ciervo D, Cella L, Pirozzi F, Parrella P, Campi G, Franco R, Varricchi G, Abete P, Marone G, Petretta M, Bonaduce D, Pacelli R, Picardi M, Tocchetti CG
* What Is the Cardiac Impact of Chemotherapy and Subsequent Radiotherapy in Lymphoma Patients? (182 views)
Antioxid Redox Signal (ISSN: 1523-0864linking, 1557-7716), 2019 Nov 20; 31 (15 ): 1166-1174.
Impact Factor: 7.581
View Export to BibTeX Export to EndNote
Avitabile C, D'Andrea LD, D'Aversa E, Milani R, Gambari R, Romanelli A
* Effect of Acylation on the Antimicrobial Activity of Temporin B Analogues (356 views)
Chemmedchem (ISSN: 1860-7179linking, 1860-7187electronic), 2018 Aug 10; 13(15): 1549-1554.
Impact Factor: 3.009
View Export to BibTeX Export to EndNote
Oliveri V, Bellia F, Viale M, Maric I, Vecchio G
* Linear polymers of beta and gamma cyclodextrins with a polyglutamic acid backbone as carriers for doxorubicin (463 views)
Carbohyd Polym (ISSN: 0144-8617), 2017 Dec 1; 177: 355-360.
Impact Factor: 5.158
View Export to BibTeX Export to EndNote
Tomasello MF, Nardon C, Lanza V, Di Natale G, Pettenuzzo N, Salmaso S, Milardi D, Caliceti P, Pappalardo G, Fregona D
* New comprehensive studies of a gold(III) Dithiocarbamate complex with proven anticancer properties: Aqueous dissolution with cyclodextrins, pharmacokinetics and upstream inhibition of the ubiquitin-proteasome pathway (515 views)
Eur J Med Chem (ISSN: 0223-5234, 1768-3254, 0223-5234linking), 2017 Jun 19; 138: 115-127.
Impact Factor: 4.816
View Export to BibTeX Export to EndNote
Diaferia C, Gianolio E, Sibillano T, Mercurio FA, Leone M, Giannini C, Balasco N, Vitagliano L, Morelli G, Accardo A
* Cross-beta nanostructures based on dinaphthylalanine Gd-conjugates loaded with doxorubicin (412 views)
Sci Rep (ISSN: 2045-2322, 2045-2322electronic, 2045-2322linking), 2017 Mar 22; 7(1): 307-307.
Impact Factor: 4.122
View Export to BibTeX Export to EndNote
Accardo A, Arena F, Gianolio E, Marasco D, Ringhieri P, Boffa C, Bardini P, Aime S, Morelli G
* Diolein based nanostructures as targeted theranostics (446 views)
J Biomed Nanotechnol (ISSN: 1550-7033), 2016; 12(5): 1076-1088.
Impact Factor: 4.521
View Export to BibTeX Export to EndNote
Cella L, Oh JH, Deasy JO, Palma G, Liuzzi R, D'Avino V, Conson M, Picardi M, Salvatore M, Pacelli R
* Predicting radiation-induced valvular heart damage (330 views)
Acta Oncol (ISSN: 0284-186x, 0284-186xlinking), 2015 Mar 24; 54(10): 1796-1804.
Impact Factor: 3.73
View Export to BibTeX Export to EndNote
Rizzitelli S, Giustetto P, Cutrin JC, Delli Castelli D, Boffa C, Ruzza M, Menchise V, Molinari F, Aime S, Terreno E
* Sonosensitive theranostic liposomes for preclinical in vivo MRI-guided visualization of doxorubicin release stimulated by pulsed low intensity non-focused ultrasound (467 views)
J Control Release (ISSN: 0168-3659), 2015 Jan 24; 202: 21-30.
Impact Factor: 7.441
View Export to BibTeX Export to EndNote
Merlo S, Basile L, Giuffrida ML, Sortino MA, Guccione S, Copani A
* Identification of 5-Methoxyflavone as a Novel DNA Polymerase-Beta Inhibitor and Neuroprotective Agent against Beta-Amyloid Toxicity (323 views)
J Nat Prod (ISSN: 0163-3864), 2015; 78(11): 2704-2711.
Impact Factor: 3.662
View Export to BibTeX Export to EndNote
Ceruso M, Carta F, Osman SM, Alothman Z, Monti SM, Supuran CT
* Inhibition studies of bacterial, fungal and protozoan β-class carbonic anhydrases with Schiff bases incorporating sulfonamide moieties (366 views)
Bioorg Med Chem (ISSN: 0968-0896, 1464-3391, 0968-0896linking), 2015; 23(15): 4181-4187.
Impact Factor: 2.923
View Export to BibTeX Export to EndNote
Ringhieri P, Diaferia C, Galdiero S, Palumbo R, Morelli G, Accardo A
* Liposomal doxorubicin doubly functionalized with CCK8 and R8 peptide sequences for selective intracellular drug delivery (450 views)
J Pept Sci (ISSN: 1075-2617, 1099-1387, 1075-2617linking), 2015; 21(5): 415-425.
Impact Factor: 1.951
View Export to BibTeX Export to EndNote
Borchmann DE, Tarallo R, Avendano S, Falanga A, Carberry TP, Galdiero S, Weck M
* Membranotropic peptide-functionalized poly(lactide)- graft -poly(ethylene glycol) brush copolymers for intracellular delivery (432 views)
Macromolecules (ISSN: 0024-9297), 2015; 48(4): 942-949.
Impact Factor: 5.554
View Export to BibTeX Export to EndNote
Milardi D, Pappalardo M
* Molecular dynamics: New advances in drug discovery (423 views)
Eur J Med Chem (ISSN: 0223-5234, 1768-3254, 0223-5234linking), 2015; 91: 1-3.
Impact Factor: 3.902
View Export to BibTeX Export to EndNote
Lolicato F, Raudino A, Milardi D, La Rosa C
* Resveratrol interferes with the aggregation of membrane-bound human-IAPP: A molecular dynamics study (529 views)
Eur J Med Chem (ISSN: 0223-5234, 1768-3254, 0223-5234linking), 2015; 92: 876-881.
Impact Factor: 3.902
View Export to BibTeX Export to EndNote
Ringhieri P, Iannitti R, Nardon C, Palumbo R, Fregona D, Morelli G, Accardo A
* Target selective micelles for bombesin receptors incorporating Au(III)-dithiocarbamato complexes (413 views)
Int J Pharm (ISSN: 0378-5173, 1873-3476), 2014 Oct 1; 473(1-2): 194-202.
Impact Factor: 3.65
View Export to BibTeX Export to EndNote
Galdiero S, Falanga A, Vitiello M, Grieco P, Caraglia M, Morelli G, Galdiero M
* Exploitation of viral properties for intracellular delivery (506 views)
J Pept Sci (ISSN: 1075-2617, 1099-1387, 1075-2617linking), 2014 Jul; 20(7): 468-478.
Impact Factor: 1.546
View Export to BibTeX Export to EndNote
Accardo A, Vitiello M, Tesauro D, Galdiero M, Finamore E, Martora F, Mansi R, Ringhieri P, Morelli G
* Self-assembled or mixed peptide amphiphile micelles from herpes simplex virus glycoproteins as potential immunomodulatory treatment (474 views)
Int J Nanomed (ISSN: 1178-2013, 1176-9114, 1176-9114linking), 2014 May 7; 9(1): 2137-2148.
Impact Factor: 4.383
View Export to BibTeX Export to EndNote
Gallicchio R, Mansueto G, Simeon V, Nardelli A, Guariglia R, Capacchione D, Soscia E, Pedicini P, Gattozzi D, Musto P, Storto G
* F-18 FDG PET/CT quantization parameters as predictors of outcome in patients with diffuse large B-cell lymphoma (484 views)
Eur J Haematol (ISSN: 0902-4441), 2014 May; 92(5): 382-389.
Impact Factor: 2.066
View Export to BibTeX Export to EndNote
Cella L, Liuzzi R, D'Avino V, Conson M, Di Biase A, Picardi M, Pugliese N, Solla R, Salvatore M, Pacelli R
* Pulmonary damage in Hodgkin's lymphoma patients treated with sequential chemo-radiotherapy: Predictors of radiation-induced lung injury (345 views)
Acta Oncol (ISSN: 0284-186x), 2014 May; 53(5): 613-619.
Impact Factor: 2.997
View Export to BibTeX Export to EndNote
Accardo A, Ringhieri P, Szekely N, Pipich V, Luchini A, Paduano L, Tesauro D
* Structural insights on nanoparticles containing gadolinium complexes as potential theranostic (436 views)
Colloid Polym Sci (ISSN: 0303-402x), 2014 May; 292(5): 1121-1127.
Impact Factor: 1.865
View Export to BibTeX Export to EndNote
Graziano G, Merlino A
* Molecular bases of protein halotolerance (363 views)
Bba-Gen Subjects (ISSN: 0925-4439, 0006-3002, 1570-9639), 2014 Apr; 1844(4): 850-858.
Impact Factor: 4.882
View Export to BibTeX Export to EndNote
Accardo A, Aloj L, Aurilio M, Morelli G, Tesauro D
* Receptor binding peptides for target-selective delivery of nanoparticles encapsulated drugs (554 views)
Int J Nanomed (ISSN: 1178-2013, 1176-9114, 1176-9114linking), 2014 Mar 27; 9(1): 1537-1557.
Impact Factor: 4.383
View Export to BibTeX Export to EndNote
Rai M, Kon K, Ingle A, Duran N, Galdiero S, Galdiero M
* Broad-spectrum bioactivities of silver nanoparticles: the emerging trends and future prospects (723 views)
Appl Microbiol Biot (ISSN: 0175-7598), 2014 Mar; 98(5): 1951-1961.
Impact Factor: 3.337
View Export to BibTeX Export to EndNote
Squeglia F, Bachert B, De Simone A, Lukomski S, Berisio R
* The crystal structure of the streptococcal collagen-like protein 2 globular domain from invasive M3-type group a streptococcus shows significant similarity to immunomodulatory HIV protein gp41 (406 views)
Jbc Papers (ISSN: 0021-9258, 1083-351x, 0021-9258linking), 2014 Feb 21; 289(8): 5122-5133.
Impact Factor: 4.573
View Export to BibTeX Export to EndNote
Romanucci V, Milardi D, Campagna T, Gaglione M, Messere A, D'Urso A, Crisafi E, La Rosa C, Zarrelli A, Balzarini J, Di Fabio G
* Synthesis, biophysical characterization and anti-HIV activity of d(TG(3)AG) Quadruplexes bearing hydrophobic tails at the 5 '-end (365 views)
Bioorg Med Chem (ISSN: 0968-0896, 1464-3391, 0968-0896linking), 2014 Feb 1; 22(3): 960-966.
Impact Factor: 2.793
View Export to BibTeX Export to EndNote
Villari V, Attanasio F, Micali N
* Control of the structural stability of α-crystallin under thermal and chemical stress: The role of carnosine (410 views)
J Phys Chem B (ISSN: 1520-6106, 1520-5207, 1520-5207linking), 2014; 118(47): 13770-13776.
Impact Factor: 3.302
View Export to BibTeX Export to EndNote
Rami M, Dubois L, Parvathaneni NK, Alterio V, van Kuijk SJ, Monti SM, Lambin P, De Simone G, Supuran CT, Winum JY
* Hypoxia-targeting carbonic anhydrase IX inhibitors by a new series of nitroimidazole-sulfonamides/sulfamides/sulfamates (544 views)
J Med Chem (ISSN: 0022-2623, 1520-4804, 0022-2623print), 2013 Nov 14; 56(21): 8512-8520.
Impact Factor: 5.48
View Export to BibTeX Export to EndNote
Petruk AA, Varriale S, Coscia MR, Mazzarella L, Merlino A, Oreste U
* The Structure Of The Cd3 Zeta Zeta Transmembrane Dimer In Popc And Raft-Like Lipid Bilayer: A Molecular Dynamics Study (441 views)
Bba-Gen Subjects (ISSN: 0005-2736, 0006-3002e, 0005-2736print), 2013 Nov; 1828(11): 2637-2645.
Impact Factor: 3.498
View Export to BibTeX Export to EndNote
De Simone G, Alterio V, Supuran CT
* Exploiting the hydrophobic and hydrophilic binding sites for designing carbonic anhydrase inhibitors (507 views)
Expert Opin Drug Discov (ISSN: 1746-0441), 2013 Jul; 8(7): 793-810.
Impact Factor: 3.467
View Export to BibTeX Export to EndNote
Accardo A, Tesauro D, Morelli G
* Peptide-based targeting strategies for simultaneous imaging and therapy with nanovectors (483 views)
Polym J (ISSN: 0032-3896), 2013 May; 45(5): 481-493.
Impact Factor: 1.554
View Export to BibTeX Export to EndNote
Falciani C, Brunetti J, Lelli B, Accardo A, Tesauro D, Morelli G, Bracci L
* Nanoparticles exposing neurotensin tumor-specific drivers (448 views)
J Pept Sci (ISSN: 1075-2617, 1099-1387, 1075-2617print), 2013 Apr; 19(4): 198-204.
Impact Factor: 1.862
View Export to BibTeX Export to EndNote
Accardo A, Mangiapia G, Paduano L, Morelli G, Tesauro D
* Octreotide labeled aggregates containing platinum complexes as nanovectors for drug delivery (406 views)
J Pept Sci (ISSN: 1075-2617, 1099-1387, 1075-2617print), 2013 Apr; 19(4): 190-197.
Impact Factor: 1.862
View Export to BibTeX Export to EndNote
Attanasio F, Convertino M, Magno A, Caflisch A, Corazza A, Haridas H, Esposito G, Cataldo S, Pignataro B, Milardi D, Rizzarelli E
* Carnosine Inhibits Abeta(42) Aggregation By Perturbing The H-Bond Network In And Around The Central Hydrophobic Cluster (618 views)
Chembiochem (ISSN: 1439-4227, 1439-7633, 1439-7633electronic), 2013 Mar 18; 14(5): 583-592.
Impact Factor: 3.06
View Export to BibTeX Export to EndNote
Galdiero S, Falanga A, Tarallo R, Russo L, Galdiero E, Cantisani M, Morelli G, Galdiero M
* Peptide inhibitors against herpes simplex virus infections (782 views)
J Pept Sci (ISSN: 1075-2617, 1099-1387, 1075-2617print), 2013 Mar; 19(3): 148-158.
Impact Factor: 1.862
View Export to BibTeX Export to EndNote
Causa F, Della Moglie R, Iaccino E, Mimmi S, Marasco D, Scognamiglio PL, Battista E, Palmieri C, Cosenza C, Sanguigno L, Quinto I, Scala G, Netti PA
* Evolutionary screening and adsorption behavior of engineered M13 bacteriophage and derived dodecapeptide for selective decoration of gold interfaces (410 views)
J Colloid Interface Sci (ISSN: 0021-9797, 1095-7103electronic, 0021-9797linking), 2013 Jan 1; 389(1): 220-229.
Impact Factor: 1.646
View Export to BibTeX Export to EndNote
Accardo A, Ringhieri P, Tesauro D, Morelli G
* Liposomes derivatized with tetrabranched neurotensin peptides via click chemistry reactions (395 views)
New J Chem (ISSN: 1144-0546), 2013; 37(11): 3528-3534.
Impact Factor: 3.159
View Export to BibTeX Export to EndNote
Accardo A, Mansi R, Salzano G, Morisco A, Aurilio M, Parisi A, Maione F, Cicala C, Ziaco B, Tesauro D, Aloj L, De Rosa G, Morelli G
* Bombesin peptide antagonist for target-selective delivery of liposomal doxorubicin on cancer cells (410 views)
Journal Of Drug Targeting (ISSN: 1061-186x), 2012 Nov 21; 21(3): 240-249.
Impact Factor: 2.768
View Export to BibTeX Export to EndNote
Magrì A, D'Alessandro F, Di Stefano DA, Campagna T, Pappalardo G, Impellizzeri G, La Mendola D
* Copper(ii) Coordination Properties Of The Integrin Ligand Sequence Phsrn And Its New Beta-Cyclodextrin Conjugates (488 views)
Journal Of Inorganic Biochemistry, 2012 Sep; 113: 15-24.
Impact Factor: 3.444
View Export to BibTeX Export to EndNote
Sciacca MF, Chillemi R, Sciuto S, Pappalardo M, La Rosa C, Grasso D, Milardi D
* Interactions of two O-phosphorylresveratrol derivatives with model membranes (337 views)
Arch Biochem Biophys (ISSN: 1096-0384, 0003-3986), 2012 May; 521(1-2): 111-116.
Impact Factor: 0
View Export to BibTeX Export to EndNote
Cella L, Conson M, Caterino M, De Rosa N, Liuzzi R, Picardi M, Grimaldi F, Solla R, Farella A, Salvatore M, Pacelli R
* Thyroid V30 predicts radiation-induced hypothyroidism in patients treated with sequential chemo-radiotherapy for Hodgkin's lymphoma (489 views) (PDF 236 views)
Int J Radiat Oncol (ISSN: 0360-3016, 1879-355x, 1879-355xelectronic), 2012 Apr 1; 82(5): 1802-1808.
Impact Factor: 4.524
View Export to BibTeX Export to EndNote
Paola LD, Paci P, Santoni D, Ruvo MD, Giuliani A
* Proteins as sponges: A statistical journey along protein structure organization principles (402 views)
J Chem Inf Model (ISSN: 1549-9596), 2012 Feb 27; 52(2): 474-482.
Impact Factor: 4.304
View Export to BibTeX Export to EndNote
Falanga A, Tarallo R, Vitiello G, Vitiello M, Perillo E, Cantisani M, D'Errico G, Galdiero M, Galdiero S
* Biophysical Characterization and Membrane Interaction of the Two Fusion Loops of Glycoprotein B from Herpes Simplex Type I Virus (487 views)
Plosone (ISSN: 1932-6203, 1932-6203electronic, 1932-6203linking), 2012 Feb 23; 7(2): N/D-N/D.
Impact Factor: 3.73
View Export to BibTeX Export to EndNote
Merlino A, Vitiello G, Grimaldi M, Sica F, Busi E, Basosi R, D’Ursi A, Fragneto G, Paduano L, D’Errico G
* Destabilization of Lipid Membranes by a Peptide Derived from Glycoprotein gp36 of Feline Immunodeficiency Virus: A Combined Molecular Dynamics/Experimental Study (455 views)
J Phys Chem B (ISSN: 1520-6106, 1520-5207, 1520-5207electronic), 2012 Jan 12; 116(1): 401-412.
Impact Factor: 3.607
View Export to BibTeX Export to EndNote
Galdiero S, Vitiello M, Falanga A, Cantisani M, Incoronato N, Galdiero M
* Intracellular Delivery: Exploiting Viral Membranotropic Peptides (708 views)
Current Drug Metabolism (ISSN: 1389-2002), 2012 Jan; 13(1): 93-104.
Impact Factor: 4.405
View Export to BibTeX Export to EndNote
Accardo A, Salsano G, Morisco A, Aurilio M, Parisi A, Maione F, Cicala C, Tesauro D, Aloj L, De Rosa G, Morelli G
* Peptide-modified liposomes for selective targeting of bombesin receptors overexpressed by cancer cells: A potential theranostic agent (380 views)
Int J Nanomed (ISSN: 1176-9114, 1178-2013, 1178-2013electronic), 2012; 7: 2007-2017.
Impact Factor: 3.463
View Export to BibTeX Export to EndNote
Satriano C, Fragalà ME, Forte G, Santoro AM, La Mendola D, Kasemo B
* Surface adsorption of fibronectin-derived peptide fragments: The influence of electrostatics and hydrophobicity for endothelial cells adhesion (307 views)
Soft Matter (ISSN: 1744-683x), 2012; 8(1): 53-56.
Impact Factor: 3.909
View Export to BibTeX Export to EndNote
Tarallo R, Accardo A, Falanga A, Guarnieri D, Vitiello G, Netti P, D'Errico G, Morelli G, Galdiero S
* Clickable functionalization of liposomes with the gH625 peptide from herpes simplex virus type i for intracellular drug delivery (457 views)
Chemistry (ISSN: 0947-6539, 1521-3765, 1521-3765electronic), 2011 Nov 4; 17(45): 12659-12668.
Impact Factor: 5.925
View Export to BibTeX Export to EndNote
Cella L, Liuzzi R, Conson M, Torre G, Caterino M, De Rosa N, Picardi M, Camera L, Solla R, Farella A, Salvatore M, Pacelli R
* Dosimetric predictors of asymptomatic heart valvular dysfunction following mediastinal irradiation for Hodgkin's lymphoma (440 views)
Radiother Oncol (ISSN: 0167-8140, 1879-0887, 1879-0887electronic), 2011 Nov; 101(2): 316-321.
Impact Factor: 5.58
View Export to BibTeX Export to EndNote
Galdiero S, Falanga A, Vitiello M, Cantisani M, Marra V, Galdiero M
* Silver Nanoparticles as Potential Antiviral Agents (759 views)
Molecules (ISSN: 1420-3049, 1420-3049electronic, 1420-3049linking), 2011 Oct; 16(10): 8894-8918.
Impact Factor: 2.386
View Export to BibTeX Export to EndNote
Cuocolo A
Current research in nuclear medicine and molecular imaging in Italy: Highlights of the 10th National Congress of the Italian Association of Nuclear Medicine and Molecular Imaging (443 views)
Q J Nucl Med Mol Im (ISSN: 1824-4785, 1824-4478, 1824-4785linking), 2011 Jun; 55(3): 280-300.
Impact Factor: 1.724
View Export to BibTeX Export to EndNote
Monfregola L, Bugatti V, Amodeo P, De Luca S, Vittoria V
* Physical and Water Sorption Properties of Chemically Modified Pectin with an Environmentally Friendly Process (281 views)
Biomacromolecules (ISSN: 1525-7797), 2011 Jun; 12(6): 2311-2318.
Impact Factor: 5.479
View Export to BibTeX Export to EndNote
Falciani C, Accardo A, Brunetti J, Tesauro D, Lelli B, Pini A, Bracci L, Morelli G
* Target-Selective Drug Delivery through Liposomes Labeled with Oligobranched Neurotensin Peptides (529 views)
Chemmedchem (ISSN: 1860-7179, 1860-7187, 1860-7187electronic), 2011 Apr 4; 6(4): 678-685.
Impact Factor: 3.151
View Export to BibTeX Export to EndNote
Lusso P, Vangelista L, Cimbro R, Secchi M, Sironi F, Longhi R, Faiella M, Maglio O, Pavone V
* Molecular engineering of RANTES peptide mimetics with potent anti-HIV-1 activity (568 views)
Faseb J (ISSN: 0892-6638, 0892-6638linking), 2011 Apr; 25(4): 1230-1243.
Impact Factor: 5.712
View Export to BibTeX Export to EndNote
Accardo A, Morisco A, Gianolio E, Tesauro D, Mangiapia G, Radulescu A, Brandt A, Morelli G
* Nanoparticles containing octreotide peptides and gadolinium complexes for MRI applications (504 views)
J Pept Sci (ISSN: 1075-2617, 1099-1387, 1075-2617print), 2011 Feb; 17(2): 154-162.
Impact Factor: 1.799
View Export to BibTeX Export to EndNote
Accardo A, Morisco A, Tesauro D, Pedone C, Morelli G
* Naposomes: A new class of peptide-derivatized, target-selective multimodal nanoparticles for imaging and therapeutic applications (407 views)
Ther Deliv (ISSN: 2041-5990), 2011 Feb; 2(2): 235-257.
Impact Factor: 0
View Export to BibTeX Export to EndNote
Morisco A, Accardo A, Tesauro D, Palumbo R, Benedetti E, Morelli G
* Peptide-labeled supramolecular aggregates as selective doxorubicin carriers for delivery to tumor cells (360 views)
Biopolymers (ISSN: 0006-3525, 0006-6352, 0006-3525print), 2011; 96(1): 88-96.
Impact Factor: 2.87
View Export to BibTeX Export to EndNote
Strianese D, Tranfa F, Finelli M, De Renzo A, Staibano S, Schiemer R, Cardone D, Pacelli R, Perna F, Mascolo M, De Rosa G, Bonavolonta G
* Hepatitis C virus infection in ocular adnexal lymphomas (337 views)
Arch Ophthalmol (ISSN: 1538-3601, 0003-9950), 2010 Oct; 128(10): 1295-1299.
Impact Factor: 3.516
View Export to BibTeX Export to EndNote
Del Vecchio S, Zannetti A, Fonti R, Iommelli F, Pizzuti LM, Lettieri A, Salvatore M
* PET/CT in cancer research: From preclinical to clinical applications (617 views)
Contrast Media Mol Imaging (ISSN: 1555-4309, 1555-4309linking), 2010 Jul; 5(4): 190-200.
Impact Factor: 4.02
View Export to BibTeX Export to EndNote
Galdiero S, Falanga A, Vitiello M, Raiola L, Russo L, Pedone C, Isernia C, Galdiero M
* The presence of a single N-terminal histidine residue enhances the fusogenic properties of a Membranotropic peptide derived from herpes simplex virus type 1 glycoprotein (471 views)
Jbc Papers (ISSN: 1083-351x, 0021-9258, 0021-9258linking), 2010 May 28; 285(22): 17123-17136.
Impact Factor: 5.328
View Export to BibTeX Export to EndNote
Kelly SE, Di Benedetto A, Greco A, Howard CM, Sollars VE, Primerano DA, Valluri JV, Claudio PP
* Rapid Selection and Proliferation of CD133(+) Cells from Cancer Cell Lines: Chemotherapeutic Implications (454 views)
Plosone (ISSN: 1932-6203, 1932-6203electronic, 1932-6203linking), 2010 Apr 8; 5(4): N/D-N/D.
Impact Factor: 4.411
View Export to BibTeX Export to EndNote
Alberobello AT, D'Esposito V, Marasco D, Doti N, Ruvo M, Bianco R, Tortora G, Esposito I, Fiory F, Miele C, Beguinot F, Formisano P
* Selective Disruption of Insulin-like Growth Factor-1 (IGF-1) Signaling via Phosphoinositide-dependent Kinase-1 Prevents the Protective Effect of IGF-1 on Human Cancer Cell Death (578 views)
Jbc Papers (ISSN: 0021-9258, 1083-351x, 0021-9258linking), 2010 Feb 26; 285(9): 6563-6572.
Impact Factor: 5.328
View Export to BibTeX Export to EndNote
Satriano C, Messina GM, Marino C, Aiello I, Conte E, La Mendola D, Distefano DA, D'Alessandro F, Pappalardo G, Impellizzeri G
* Surface immobilization of fibronectin-derived PHSRN peptide on functionalized polymer films - Effects on fibroblast spreading (532 views)
J Colloid Interface Sci (ISSN: 1095-7103electronic, 0021-9797linking), 2010 Jan 15; 341(2): 232-239.
Impact Factor: 3.068
View Export to BibTeX Export to EndNote
Storto G, De Renzo A, Pellegrino T, Perna F, De Falco T, Erra P, Nardelli A, Speranza A, Klain M, Rotoli B, Pace L
* Assessment of Metabolic Response to Radioimmunotherapy with (90)Y-Ibritumomab Tiuxetan in Patients with Relapsed or Refractory B-Cell Non-Hodgkin Lymphoma (399 views)
Radiology (ISSN: 0033-8419, 1527-1315, 0033-8419linking), 2010 Jan; 254(1): 245-252.
Impact Factor: 6.069
View Export to BibTeX Export to EndNote
Puglisi A, Rizzarelli E, Vecchio G, Iacovino R, Benedetti E, Pedone C, Saviano M
* Crystal And Molecular Structure Of Beta-Cyclodextrins Functionalized With The Anti-Inflammatory Drug Etodolac (415 views)
Biopolymers (ISSN: 0006-3525, 0006-6352, 0006-3525print), 2009 Dec; 91(12): 1227-1235.
Impact Factor: 2.605
View Export to BibTeX Export to EndNote
Vitagliano L, Stanzione F, De Simone A, Esposito L
* Dynamics and Stability of Amyloid-Like Steric Zipper Assemblies with Hydrophobic Dry Interfaces (451 views)
Biopolymers (ISSN: 0006-3525, 0006-6352, 0006-3525print), 2009 Dec; 91(12): 1161-1171.
Impact Factor: 2.605
View Export to BibTeX Export to EndNote
D'Auria G, Vacatello M, Falcigno L, Paduano L, Mangiapia G, Calvanese L, Gambaretto R, Dettin M, Paolillo L
* Self-assembling properties of ionic-complementary peptides (483 views)
J Pept Sci (ISSN: 1075-2617, 1099-1387, 1075-2617print), 2009 Mar; 15(3): 210-219.
Impact Factor: 1.807
View Export to BibTeX Export to EndNote
Kaczmarek K, Farina B, Zubrzak P, Jankowski S, Zimecki M, Suder P, Benedetti E, Fattorusso R, Saviano M, Zabrocki J
* Synthesis, conformational analysis and immunological activity of β3Phe-substituted Cyclolinopeptide A analogues (460 views)
J Pept Sci (ISSN: 1075-2617, 1099-1387, 1075-2617print), 2009 Mar; 15(3): 166-174.
Impact Factor: 1.807
View Export to BibTeX Export to EndNote
Ruggiero A, Tizzano B, Pedone E, Pedone C, Wilmanns M, Berisio R
* Crystal Structure of the Resuscitation-Promoting Factor (Delta DUF)RpfB from M. tuberculosis (570 views)
J Mol Biol (ISSN: 0022-2836, 1089-8638, 1089-8638electronic), 2009 Jan 9; 385(1): 153-162.
Impact Factor: 3.871
View Export to BibTeX Export to EndNote
Vaccaro M, Mangiapia G, Accardo A, Tesauro D, Gianolio E, Frielinghaus H, Morelli G, Paduano L
* Polymerized mixed aggregates containing gadolinium complex and CCK8 peptide (377 views)
Colloid Polym Sci (ISSN: 0303-402x), 2008 Dec; 286(14-15): 1643-1652.
Impact Factor: 1.736
View Export to BibTeX Export to EndNote
Galdiero S, Falanga A, Vitiello M, Raiola L, Fattorusso R, Browne H, Pedone C, Isernia C, Galdiero M
* Analysis of a membrane interacting region of herpes simplex virus type 1 glycoprotein (544 views)
Jbc Papers (ISSN: 0021-9258, 1083-351x, 0021-9258linking), 2008 Oct 31; 283(44): 29993-30009.
Impact Factor: 5.52
View Export to BibTeX Export to EndNote
Sciacca MFM, Pappalardo M, Milardi D, Grasso DM, La Rosa C
* Calcium-Activated Membrane Interaction Of The Islet Amyloid Polypeptide: Implications In The Pathogenesis Of Type Ii Diabetes Mellitus (962 views)
Arch Biochem Biophys, 2008 Sep 15; 65(1-2): 291-298.
Impact Factor: 3.043
View Export to BibTeX Export to EndNote
Woo LWL, Fischer DS, Sharland CM, Trusselle M, Foster PA, Chander SK, Di Fiore A, Supuran CT, De Simone G, Purohit A, Reed MJ, Potter BVL
* Anticancer steroid sulfatase inhibitors: synthesis of a potent fluorinated second-generation agent, in vitro and in vivo activities, molecular modeling, and protein crystallography (643 views)
Mol Cancer Ther (ISSN: 1535-7163, 1538-8514electronic), 2008 Sep; 7(8): 2435-2444.
Impact Factor: 5.003
View Export to BibTeX Export to EndNote
Accardo A, Tesauro D, Del Pozzo L, Mangiapia G, Paduano L, Morelli G
* Micelles by self-assembling peptide-conjugate amphiphile: Synthesis and structural characterization (402 views)
J Pept Sci (ISSN: 1075-2617, 1099-1387, 1075-2617print), 2008 Sep; 14(8): 903-910.
Impact Factor: 1.654
View Export to BibTeX Export to EndNote
Hesse B, Lindhardt TB, Acampa W, Anagnostopoulos C, Ballinger J, Bax JJ, Edenbrandt L, Flotats A, Germano G, Stopar TG, Franken P, Kelion A, Kjaer A, Le Guludec D, Ljungberg M, Maenhout AF, Marcassa C, Marving J, Mckiddie F, Schaefer WM, Stegger L, Underw
* EANM/ESC guidelines for radionuclide imaging of cardiac function (569 views)
Eur J Nucl Med (ISSN: 1619-7070, 1619-7089, 0340-6997), 2008 Apr; 35(4): 851-885.
Impact Factor: 4.532
View Export to BibTeX Export to EndNote
Galdiero S, Vitiello M, D'Isanto M, Falanga A, Cantisani M, Browne H, Pedone C, Galdiero M
* The identification and characterization of fusogenic domains in herpes virus glycoprotein B molecules (460 views)
Chembiochem (ISSN: 1439-7633, 1439-4227, 1439-7633electronic), 2008 Mar 25; 9(5): 758-767.
Impact Factor: 3.322
View Export to BibTeX Export to EndNote
Malgieri G, Russo L, Esposito S, Baglivo I, Zaccaro L, Pedone EM, Di Blasio B, Isernia C, Pedone PV, Fattorusso R
* The Prokaryotic Cys2his2 Zinc Finger Domain Adopts A Novel Fold As Revealed By The Solution Structure Of Agrobacterium Tumefaciens Ros Dna Binding Domain (382 views)
P Natl Acad Sci Usa (ISSN: 0027-8424, 1091-6490, 0027-8424print), 2007 Oct 30; 104(44): 17341-17346.
Impact Factor: 9.598
View Export to BibTeX Export to EndNote
Calabrese V, Mancuso C, Calvani M, Rizzarelli E, Butterfield DA, Stella AM
* Nitric oxide in the central nervous system: neuroprotection versus neurotoxicity (698 views)
Nature Reviews Neuroscience (ISSN: 1471-0048), 2007 Oct; 8(10): 766-775.
Impact Factor: 24.52
View Export to BibTeX Export to EndNote
Tarantino G, Gentile A, Capone D, Basile V, Tarantino M, Di Minno MN, Cuocolo A, Conca P
* Does protracted antiviral therapy impact on HCV-related liver cirrhosis progression? (312 views)
World J Gastroentero (ISSN: 1007-9327, 2219-2840, 1007-9327linking), 2007 Sep 28; 13(36): 4903-4908.
Impact Factor: 2.433
View Export to BibTeX Export to EndNote
Galdiero S, Falanga A, Vitiello M, D'Isanto M, Collins C, Orrei V, Browne H, Pedone C, Galdiero M
* Evidence for a role of the membrane-proximal region of herpes simplex virus type 1 glycoprotein H in membrane fusion and virus inhibition (583 views)
Chembiochem (ISSN: 1439-4227, 1439-7633, 1439-7633electronic), 2007 May 25; 8(8): 885-895.
Impact Factor: 3.446
View Export to BibTeX Export to EndNote
Accardo A, Tesauro D, Mangiapia G, Pedone C, Morelli G
* Nanostructures by self-assembling peptide amphiphile as potential selective drug carriers (426 views)
Biopolymers (ISSN: 0006-3525, 0006-6352, 0006-3525print), 2007; 88(2): 115-121.
Impact Factor: 2.389
View Export to BibTeX Export to EndNote
Menchise V, De Simone G, Di Fiore A, Scozzafava A, Supuran CT
* Carbonic anhydrase inhibitors: X-ray crystallographic studies for the binding of 5-amino-1, 3, 4-thiadiazole-2-sulfonamide and 5-(4-amino-3-chloro-5-fluorophenylsulfonamido)1, 3, 4-thiadiazole-2-sulfon amide to human isoform II (308 views)
Bioorganic & Medicinal Chemistry Letters (ISSN: 0960-894x), 2006 Dec 15; 16(24): 6204-6208.
Impact Factor: 2.538
View Export to BibTeX Export to EndNote
Dalla Bona A, Formaggio F, Peggion C, Kaptein B, Broxterman Quirinus B, Galdiero S, Galdiero M, Vitiello M, Benedetti E, Toniolo C
* Synthesis, conformation, and bioactivity of novel analogues of the antiviral lipopeptide halovir (464 views)
J Pept Sci (ISSN: 1075-2617, 1099-1387, 1075-2617print), 2006 Dec; 12(12): 748-757.
Impact Factor: 1.801
View Export to BibTeX Export to EndNote
Calvanese L, Saporito A, Marasco D, D'Auria G, Minchiotti G, Pedone C, Paolillo L, Falcigno L, Ruvo M
* Solution structure of mouse Cripto CFC domain and its inactive variant Trp107Ala (379 views)
J Med Chem (ISSN: 0022-2623, 1520-4804, 0022-2623print), 2006 Nov 30; 49(24): 7054-7062.
Impact Factor: 5.115
View Export to BibTeX Export to EndNote
De Simone G, Vitale RM, Di Fiore A, Pedone C, Scozzafava A, Montero JL, Winum JY, Supuran CT
* Carbonic anhydrase inhibitors: Hypoxia-activatable sulfonamides incorporating disulfide bonds that target the tumor-associated isoform IX (473 views)
J Med Chem (ISSN: 0022-2623, 1520-4804, 0022-2623print), 2006 Sep 7; 49(18): 5544-5551.
Impact Factor: 5.115
View Export to BibTeX Export to EndNote
De Renzo A, Perna F, Persico M, Mainolfi C, Pace L
* 18F-fluorodeoxyglucose positron emission tomography/computed tomography in the evaluation of early response in a primary hepatic lymphoma (233 views)
Br J Haematol (ISSN: 0007-1048, 0007-1048linking, 1365-2141electronic), 2006 Jun; 133(6): 580-580.
Impact Factor: 4.498
View Export to BibTeX Export to EndNote
Cappiello M, Alterio V, Amodeo P, Del Corso A, Scaloni A, Pedone C, Moschini R, De Donatis GM, De Simone G, Mura U
* A new spot test for sulfhydryl-containing compounds (449 views)
Anal Biochem, 2006 Mar 14; 79(1-2): 610-611.
Impact Factor: 2.305
View Export to BibTeX Export to EndNote
Cappiello M, Alterio V, Amodeo P, Del Corso A, Scaloni A, Pedone C, Moschini R, De Donatis GM, De Simone G, Mura U
* Metal ion substitution in the catalytic site greatly affects the binding of sulfhydryl-containing compounds to leucyl aminopeptidase (691 views)
Biochemistry (ISSN: 0006-2960, 1520-4995, 1520-4995electronic), 2006 Mar 14; 45(10): 3226-3234.
Impact Factor: 3.633
View Export to BibTeX Export to EndNote
Mannini R, Rivieccio V, D'Auria S, Tanfani F, Ausili A, Pedone C, Grimaldi G, Facchiano A
* Structure/function of KRAB repression domains: Structural properties of KRAB modules inferred from hydrodynamic, circular dichroism, and FTIR spectroscopic analyses (552 views)
Proteins (ISSN: 0887-3585, 1097-0134, 1097-0134electronic), 2006 Feb 15; 62(3): 604-616.
Impact Factor: 3.73
View Export to BibTeX Export to EndNote
De Capua A, Goodman M, Amino Y, Saviano M, Benedetti E
* Conformation analysis of aspartame-based sweeteners by NMR spectroscopy, molecular dynamics simulations, and X-ray diffraction studies (613 views)
Chembiochem (ISSN: 1439-4227, 1439-7633, 1439-7633electronic), 2006 Feb; 7(2): 377-387.
Impact Factor: 4.1
View Export to BibTeX Export to EndNote
Di Fiore A, Pedone C, D'Ambrosio K, Scozzafava A, De Simone G, Supuran CT
* Carbonic anhydrase inhibitors: Valdecoxib binds to a different active site region of the human isoform II as compared to the structurally related cyclooxygenase II 'selective' inhibitor celecoxib (323 views)
Bioorg Med Chem Lett Bioorganic And Medicinal Chemistry Letters (ISSN: 0960-894x), 2006 Jan 15; 16(2): 437-442.
Impact Factor: 2.538
View Export to BibTeX Export to EndNote
Menchise V, De Simone G, Alterio V, Di Fiore A, Pedone C, Scozzafava A, Supuran CT
* Carbonic anhydrase inhibitors: Stacking with Phe131 determines active site binding region of inhibitors as exemplified by the X-ray crystal structure of a membrane-impermeant antitumor sulfonamide complexed with isozyme II (478 views)
J Med Chem (ISSN: 0022-2623, 1520-4804, 0022-2623print), 2005 Sep 8; 48(18): 5721-5727.
Impact Factor: 4.926
View Export to BibTeX Export to EndNote
Galdiero S, Falanga A, Vitiello M, Browne H, Pedone C, Galdiero M
* Fusogenic domains in herpes simplex virus type 1 glycoprotein (590 views)
Jbc Papers (ISSN: 0021-9258, 1083-351x, 0021-9258linking), 2005 Sep 5; 280(31): 28632-28643.
Impact Factor: 5.854
View Export to BibTeX Export to EndNote
Vacatello M, D'Auria G, Falcigno L, Dettin M, Gambaretto R, Di Bello C, Paolillo L
* Conformational Analysis Of Novel Heparin Binding Peptides (618 views)
Biomaterials (ISSN: 0142-9612, 1878-5905electronic, 0142-9612linking), 2005 Jun; 26(16): 3207-3214.
Impact Factor: 4.698
View Export to BibTeX Export to EndNote
Di Fiore A, De Simone G, Menchise V, Pedone C, Casini A, Scozzafava A, Supuran CT
* Carbonic anhydrase inhibitors: X-ray crystal structure of a benzenesulfonamide strong CA II and CA IX inhibitor bearing a pentafluorophenylaminothioureido tail in complex with isozyme II (489 views)
Bioorg Med Chem Lett Bioorganic And Medicinal Chemistry Letters (ISSN: 0960-894x), 2005 Apr 1; 15(7): 1937-1942.
Impact Factor: 2.478
View Export to BibTeX Export to EndNote
Di Natale G, Impellizzeri G, Pappalardo G
* Conformational properties of peptide fragments homologous to the 106-114 and 106-126 residues of the human prion protein: a CD and NMR spectroscopic study (419 views)
Org Biomol Chem (ISSN: 1477-0520, 1477-0539, 1477-0539electronic), 2005 Feb 7; 3(3): 490-497.
Impact Factor: 2.547
View Export to BibTeX Export to EndNote
Pappalardo M, Milardi D, La Rosa C, Zannoni C, Rizzarelli E, Grasso D
* A molecular dynamics study on the conformational stability of PrP 180-193 helix II prion fragment (306 views)
Chem Phys Lett (ISSN: 0009-2614), 2004 Jun 1; 390(4-6): 511-516.
Impact Factor: 2.438
View Export to BibTeX Export to EndNote
Accardo A, Tesauro D, Roscigno P, Gianolio E, Paduano L, D'Errico G, Pedone C, Morelli G
* Physicochemical Properties of Mixed Micellar Aggregates Containing CCK Peptides and Gd Complexes Designed as Tumor Specific Contrast Agents in MRI (452 views)
J Am Chem Soc (ISSN: 0002-7863, 0002-2786, 1520-5126), 2004 Mar 17; 126(10): 3097-3107.
Impact Factor: 6.903
View Export to BibTeX Export to EndNote
De Capua A, Del Gatto A, Zaccaro L, Saviano G, Carlucci A, Livigni A, Gedressi C, Tancredi T, Pedone C, Saviano M
* A synthetic peptide reproducing the mitochondrial targeting motif of AKAP121: A conformational study (460 views)
Biopolymers (ISSN: 0006-3525, 0006-6352, 0006-3525print), 2004; 76(6): 459-466.
Impact Factor: 2.863
View Export to BibTeX Export to EndNote
Galdiero S, Vitiello M, D'Isanto M, Di Niola E, Peluso L, Raieta K, Pedone C, Galdiero M, Benedetti E
* Induction of signaling pathways by herpes simplex virus type 1 through glycoprotein H peptides (589 views)
Biopolymers (ISSN: 0006-3525, 0006-6352, 0006-3525print), 2004; 76(6): 494-502.
Impact Factor: 2.863
View Export to BibTeX Export to EndNote
Mainenti PP, Romano L, Contegiacomo A, Romano M, Casella V, Cuccuru A, Insabato L, Salvatore M
* Rare diffuse peritoneal malignant neoplasms: CT findings in two cases (245 views)
Abdom Imaging (ISSN: 0942-8925, 1432-0509), 2003 Nov; 28(6): 827-830.
Impact Factor: 0.996
View Export to BibTeX Export to EndNote
Portella G, Pacelli R, Libertini S, Cella L, Vecchio G, Salvatore M, Fusco A
* ONYX-015 Enhances Radiation-Induced Death of Human Anaplastic Thyroid Carcinoma Cells (436 views)
J Clin Endocrinol Metab Journal Of Clinical Endocrinology And Metabolism (ISSN: 0021-972x), 2003 Oct 1; 88(10): 5027-5032.
Impact Factor: 5.873
View Export to BibTeX Export to EndNote
Tauchmanova L, De Rosa G, Serio B, Fazioli F, Mainolfi C, Lombardi G, Colao A, Salvatore M, Rotoli B, Selleri C
* Avascular necrosis in long-term survivors after allogeneic or autologous stem cell transplantation: A single center experience and a review (275 views)
Cancer (ISSN: 0008-543x), 2003 May 15; 97(10): 2453-2461.
Impact Factor: 2.045
View Export to BibTeX Export to EndNote
Grasso D, Milardi D, Guantieri V, La Rosa C, Rizzarelli E
* Interaction of prion peptide PrP 180-193 with DPPC model membranes: A thermodynamic study (383 views)
New J Chem (ISSN: 1144-0546), 2003; 27(2): 359-364.
Impact Factor: 2.272
View Export to BibTeX Export to EndNote
Acampa W, Petretta M, Cuocolo A
* Nuclear medicine procedures in cardiovascular diseases: An evidence based approach (466 views)
Q J Nucl Med (ISSN: 1124-3937, 1125-0135), 2002 Dec; 46(4): 323-330.
Impact Factor: 1.903
View Export to BibTeX Export to EndNote
Grasso D, Milardi D, La Rosa C, Impellizzeri G, Pappalardo G
* The interaction of a peptide with a scrambled hydrophobic/hydrophilic sequence (Pro-Asp-Ala-Asp-Ala-His-Ala-His-Ala-His-Ala-Ala-Ala-His-Gly) (PADH) with DPPC model membranes: A DSC study (274 views)
Thermochim Acta (ISSN: 0040-6031), 2002 Jul 15; 390(1-2): 73-78.
Impact Factor: 0.974
View Export to BibTeX Export to EndNote
Goodman M, Del Valle JR, Amino Y, Benedetti E
* Molecular basis of sweet taste in dipeptide taste ligands (245 views)
Pure Appl Chem (ISSN: 0033-4545), 2002; 74(7): 1109-1116.
Impact Factor: 1.75
View Export to BibTeX Export to EndNote
Masullo M, Cantiello P, Paola B, Fiengo A, Vitagliano L, Zagari A, Arcari P
* Valine114 Replacements In The Archaeal Elongation Factor 1a Enhanced Its Ability To Interact With Aminoacyl-Trna And Kirromycin (352 views)
Biochemistry (ISSN: 0006-2960, 1520-4995, 1520-4995electronic), 2002; 41(49): 14482-14488.
Impact Factor: 4.064
View Export to BibTeX Export to EndNote
De Simone G, Menchise V, Manco G, Mandrich L, Sorrentino N, Lang D, Rossi M, Pedone C
* The crystal structure of a hyper-thermophilic carboxylesterase from the archaeon Archaeoglobus fulgidus (422 views)
J Mol Biol (ISSN: 0022-2836, 1089-8638, 1089-8638electronic), 2001 Nov 30; 314(3): 507-518.
Impact Factor: 5.826
View Export to BibTeX Export to EndNote
Menchise V, Corbier C, Didierjean C, Saviano M, Benedetti E, Jacquot JP, Aubry A
* Crystal structure of the wild-type and D30A mutant thioredoxin h of Chlamydomonas reinhardtii and implications for the catalytic mechanism (405 views)
Biochem J (ISSN: 0264-6021, 1470-8728electronic, 0264-6021linking), 2001 Oct 1; 359(1): 65-75.
Impact Factor: 4.326
View Export to BibTeX Export to EndNote
Saviano G, Rossi F, Benedetti E, Pedone C, Mierke DF, Maione A, Zanotti G, Tancredi T, Saviano M
* Structural consequences of metal complexation of cyclo[Pro-Phe-Phe-Ala-Xaa]2 decapeptides (447 views)
Chemistry (ISSN: 0947-6539, 1521-3765, 1521-3765electronic), 2001 Mar 16; 7(6): 1176-1183.
Impact Factor: 4.614
View Export to BibTeX Export to EndNote
Grasso D, Milardi D, La Rosa C, Rizzarelli E
* DSC study of the interaction of the prion peptide PrP106-126 with artificial membranes (377 views)
New J Chem (ISSN: 1144-0546), 2001; 25(12): 1543-1548.
Impact Factor: 2.44
View Export to BibTeX Export to EndNote
Esposito L, Vitagliano L, Sica F, Sorrentino G, Zagari A, Mazzarella L
The ultrahigh resolution crystal structure of ribonuclease A containing an isoaspartyl residue: Hydration and sterochemical analysis (668 views)
J Mol Biol (ISSN: 0022-2836, 1089-8638, 1089-8638electronic), 2000 Mar 31; 297(3): 713-732.
Impact Factor: 5.388
View Export to BibTeX Export to EndNote
Levchenko A, Mehta B, Spengler BA, Narkar A, Fonti R, Biedler JL, Tsuruo T, Larson SM
Measurement of P-glycoprotein expression in multidrug-resistant human neuroblastoma cell lines using self-competitive binding assay (283 views)
Anal Biochem (ISSN: 0003-2697, 1096-0309electronic, 0003-2697linking), 1996 May 1; 236(2): 338-343.
Impact Factor: 2.017
View Export to BibTeX Export to EndNote
MAUREA S, LASTORIA S, CARACO C, INDOLFI P, CASALE F, DITULLIO M, SALVATORE M
IODINE-131-MIBG IMAGING TO MONITOR CHEMOTHERAPY RESPONSE IN ADVANCED NEUROBLASTOMA - COMPARISON WITH LABORATORY ANALYSIS (327 views)
J Nucl Med (ISSN: 0161-5505, 1535-5667, 1535-5667electronic), 1994 Sep; 35(9): 1429-1435.
Impact Factor: 3.491
View Export to BibTeX Export to EndNote
Correale P, Caraglia M, Pepe S, Ricciardi B, Barile C, Montagnani S, Pacelli R, Bianco A, Tagliaferri P
PHORBOL 12-MYRISTATE 13-ACETATE (PMA) INDUCES NEUROENDOCRINE-LIKE DIFFERENTIATION AND REVERSES DOXORUBICIN-RESISTANCE OF HUMAN COLON-CARCINOMA CELLS IN-VITRO (299 views)
Int J Oncol (ISSN: 1019-6439, 1791-2423electronic, 1019-6439linking), 1994 Feb; 4(2): 423-427.
Impact Factor: 1.181
View Export to BibTeX Export to EndNote
Di Blasio B, Pavone V, Nastri F, Isernia C, Saviano M, Pedone C, Cucinotta V, Impellizzeri G, Rizzarelli E, Vecchio G
Conformation for a β-cyclodextrin monosubstituted with a cyclic dipeptide (485 views)
P Natl Acad Sci Usa (ISSN: 0027-8424, 1091-6490, 0027-8424print), 1992 Sep 1; 89(15): 7218-7221.
Impact Factor: 9.04
View Export to BibTeX Export to EndNote
Scala S, Pacelli R, Iaffaioli RV, Normanno N, Pepe S, Frasci G, Genua G, Tsuruo T, Tagliaferri P, Bianco AR
Reversal of adriamycin resistance by recombinant α-interferon in multidrug-resistant human colon carcinoma LoVo-doxorubicin cells (559 views)
Cancer Res (ISSN: 0008-5472, 1538-7445, 1538-7445electronic), 1991 Sep 15; 51(18): 4898-4902.
Impact Factor: 8.426
View Export to BibTeX Export to EndNote
* GlucoCEST MRI for the Evaluation Response to Chemotherapeutic and Metabolic Treatments in a Murine Triple-Negative Breast Cancer: A Comparison with[(18)F]F-FDG-PET (12 views)
Mol Imaging Biol (ISSN: 1536-1632linking), 2021 Aug 12; N/D: N/D-N/D.
Impact Factor:
View Export to BibTeX Export to EndNote
Cozzolino A, Vergalito F, Tremonte P, Iorizzo M, Lombardi SJ, Sorrentino E, Luongo D, Coppola R, Marco RD, Succi M
* Preliminary Evaluation of the Safety and Probiotic Potential of Akkermansia muciniphila DSM 22959 in Comparison with Lactobacillus rhamnosus GG (172 views)
Microorganisms (ISSN: 2076-2607linking), 2020 Jan 30; 8(2): N/D-N/D.
Impact Factor: 4.167
View Export to BibTeX Export to EndNote
Mercurio V, Cuomo A, Della Pepa R, Ciervo D, Cella L, Pirozzi F, Parrella P, Campi G, Franco R, Varricchi G, Abete P, Marone G, Petretta M, Bonaduce D, Pacelli R, Picardi M, Tocchetti CG
* What Is the Cardiac Impact of Chemotherapy and Subsequent Radiotherapy in Lymphoma Patients? (182 views)
Antioxid Redox Signal (ISSN: 1523-0864linking, 1557-7716), 2019 Nov 20; 31 (15 ): 1166-1174.
Impact Factor: 7.581
View Export to BibTeX Export to EndNote
Avitabile C, D'Andrea LD, D'Aversa E, Milani R, Gambari R, Romanelli A
* Effect of Acylation on the Antimicrobial Activity of Temporin B Analogues (356 views)
Chemmedchem (ISSN: 1860-7179linking, 1860-7187electronic), 2018 Aug 10; 13(15): 1549-1554.
Impact Factor: 3.009
View Export to BibTeX Export to EndNote
Oliveri V, Bellia F, Viale M, Maric I, Vecchio G
* Linear polymers of beta and gamma cyclodextrins with a polyglutamic acid backbone as carriers for doxorubicin (463 views)
Carbohyd Polym (ISSN: 0144-8617), 2017 Dec 1; 177: 355-360.
Impact Factor: 5.158
View Export to BibTeX Export to EndNote
Tomasello MF, Nardon C, Lanza V, Di Natale G, Pettenuzzo N, Salmaso S, Milardi D, Caliceti P, Pappalardo G, Fregona D
* New comprehensive studies of a gold(III) Dithiocarbamate complex with proven anticancer properties: Aqueous dissolution with cyclodextrins, pharmacokinetics and upstream inhibition of the ubiquitin-proteasome pathway (515 views)
Eur J Med Chem (ISSN: 0223-5234, 1768-3254, 0223-5234linking), 2017 Jun 19; 138: 115-127.
Impact Factor: 4.816
View Export to BibTeX Export to EndNote
Diaferia C, Gianolio E, Sibillano T, Mercurio FA, Leone M, Giannini C, Balasco N, Vitagliano L, Morelli G, Accardo A
* Cross-beta nanostructures based on dinaphthylalanine Gd-conjugates loaded with doxorubicin (412 views)
Sci Rep (ISSN: 2045-2322, 2045-2322electronic, 2045-2322linking), 2017 Mar 22; 7(1): 307-307.
Impact Factor: 4.122
View Export to BibTeX Export to EndNote
Accardo A, Arena F, Gianolio E, Marasco D, Ringhieri P, Boffa C, Bardini P, Aime S, Morelli G
* Diolein based nanostructures as targeted theranostics (446 views)
J Biomed Nanotechnol (ISSN: 1550-7033), 2016; 12(5): 1076-1088.
Impact Factor: 4.521
View Export to BibTeX Export to EndNote
Cella L, Oh JH, Deasy JO, Palma G, Liuzzi R, D'Avino V, Conson M, Picardi M, Salvatore M, Pacelli R
* Predicting radiation-induced valvular heart damage (330 views)
Acta Oncol (ISSN: 0284-186x, 0284-186xlinking), 2015 Mar 24; 54(10): 1796-1804.
Impact Factor: 3.73
View Export to BibTeX Export to EndNote
Rizzitelli S, Giustetto P, Cutrin JC, Delli Castelli D, Boffa C, Ruzza M, Menchise V, Molinari F, Aime S, Terreno E
* Sonosensitive theranostic liposomes for preclinical in vivo MRI-guided visualization of doxorubicin release stimulated by pulsed low intensity non-focused ultrasound (467 views)
J Control Release (ISSN: 0168-3659), 2015 Jan 24; 202: 21-30.
Impact Factor: 7.441
View Export to BibTeX Export to EndNote
Merlo S, Basile L, Giuffrida ML, Sortino MA, Guccione S, Copani A
* Identification of 5-Methoxyflavone as a Novel DNA Polymerase-Beta Inhibitor and Neuroprotective Agent against Beta-Amyloid Toxicity (323 views)
J Nat Prod (ISSN: 0163-3864), 2015; 78(11): 2704-2711.
Impact Factor: 3.662
View Export to BibTeX Export to EndNote
Ceruso M, Carta F, Osman SM, Alothman Z, Monti SM, Supuran CT
* Inhibition studies of bacterial, fungal and protozoan β-class carbonic anhydrases with Schiff bases incorporating sulfonamide moieties (366 views)
Bioorg Med Chem (ISSN: 0968-0896, 1464-3391, 0968-0896linking), 2015; 23(15): 4181-4187.
Impact Factor: 2.923
View Export to BibTeX Export to EndNote
Ringhieri P, Diaferia C, Galdiero S, Palumbo R, Morelli G, Accardo A
* Liposomal doxorubicin doubly functionalized with CCK8 and R8 peptide sequences for selective intracellular drug delivery (450 views)
J Pept Sci (ISSN: 1075-2617, 1099-1387, 1075-2617linking), 2015; 21(5): 415-425.
Impact Factor: 1.951
View Export to BibTeX Export to EndNote
Borchmann DE, Tarallo R, Avendano S, Falanga A, Carberry TP, Galdiero S, Weck M
* Membranotropic peptide-functionalized poly(lactide)- graft -poly(ethylene glycol) brush copolymers for intracellular delivery (432 views)
Macromolecules (ISSN: 0024-9297), 2015; 48(4): 942-949.
Impact Factor: 5.554
View Export to BibTeX Export to EndNote
Milardi D, Pappalardo M
* Molecular dynamics: New advances in drug discovery (423 views)
Eur J Med Chem (ISSN: 0223-5234, 1768-3254, 0223-5234linking), 2015; 91: 1-3.
Impact Factor: 3.902
View Export to BibTeX Export to EndNote
Lolicato F, Raudino A, Milardi D, La Rosa C
* Resveratrol interferes with the aggregation of membrane-bound human-IAPP: A molecular dynamics study (529 views)
Eur J Med Chem (ISSN: 0223-5234, 1768-3254, 0223-5234linking), 2015; 92: 876-881.
Impact Factor: 3.902
View Export to BibTeX Export to EndNote
Ringhieri P, Iannitti R, Nardon C, Palumbo R, Fregona D, Morelli G, Accardo A
* Target selective micelles for bombesin receptors incorporating Au(III)-dithiocarbamato complexes (413 views)
Int J Pharm (ISSN: 0378-5173, 1873-3476), 2014 Oct 1; 473(1-2): 194-202.
Impact Factor: 3.65
View Export to BibTeX Export to EndNote
Galdiero S, Falanga A, Vitiello M, Grieco P, Caraglia M, Morelli G, Galdiero M
* Exploitation of viral properties for intracellular delivery (506 views)
J Pept Sci (ISSN: 1075-2617, 1099-1387, 1075-2617linking), 2014 Jul; 20(7): 468-478.
Impact Factor: 1.546
View Export to BibTeX Export to EndNote
Accardo A, Vitiello M, Tesauro D, Galdiero M, Finamore E, Martora F, Mansi R, Ringhieri P, Morelli G
* Self-assembled or mixed peptide amphiphile micelles from herpes simplex virus glycoproteins as potential immunomodulatory treatment (474 views)
Int J Nanomed (ISSN: 1178-2013, 1176-9114, 1176-9114linking), 2014 May 7; 9(1): 2137-2148.
Impact Factor: 4.383
View Export to BibTeX Export to EndNote
Gallicchio R, Mansueto G, Simeon V, Nardelli A, Guariglia R, Capacchione D, Soscia E, Pedicini P, Gattozzi D, Musto P, Storto G
* F-18 FDG PET/CT quantization parameters as predictors of outcome in patients with diffuse large B-cell lymphoma (484 views)
Eur J Haematol (ISSN: 0902-4441), 2014 May; 92(5): 382-389.
Impact Factor: 2.066
View Export to BibTeX Export to EndNote
Cella L, Liuzzi R, D'Avino V, Conson M, Di Biase A, Picardi M, Pugliese N, Solla R, Salvatore M, Pacelli R
* Pulmonary damage in Hodgkin's lymphoma patients treated with sequential chemo-radiotherapy: Predictors of radiation-induced lung injury (345 views)
Acta Oncol (ISSN: 0284-186x), 2014 May; 53(5): 613-619.
Impact Factor: 2.997
View Export to BibTeX Export to EndNote
Accardo A, Ringhieri P, Szekely N, Pipich V, Luchini A, Paduano L, Tesauro D
* Structural insights on nanoparticles containing gadolinium complexes as potential theranostic (436 views)
Colloid Polym Sci (ISSN: 0303-402x), 2014 May; 292(5): 1121-1127.
Impact Factor: 1.865
View Export to BibTeX Export to EndNote
Graziano G, Merlino A
* Molecular bases of protein halotolerance (363 views)
Bba-Gen Subjects (ISSN: 0925-4439, 0006-3002, 1570-9639), 2014 Apr; 1844(4): 850-858.
Impact Factor: 4.882
View Export to BibTeX Export to EndNote
Accardo A, Aloj L, Aurilio M, Morelli G, Tesauro D
* Receptor binding peptides for target-selective delivery of nanoparticles encapsulated drugs (554 views)
Int J Nanomed (ISSN: 1178-2013, 1176-9114, 1176-9114linking), 2014 Mar 27; 9(1): 1537-1557.
Impact Factor: 4.383
View Export to BibTeX Export to EndNote
Rai M, Kon K, Ingle A, Duran N, Galdiero S, Galdiero M
* Broad-spectrum bioactivities of silver nanoparticles: the emerging trends and future prospects (723 views)
Appl Microbiol Biot (ISSN: 0175-7598), 2014 Mar; 98(5): 1951-1961.
Impact Factor: 3.337
View Export to BibTeX Export to EndNote
Squeglia F, Bachert B, De Simone A, Lukomski S, Berisio R
* The crystal structure of the streptococcal collagen-like protein 2 globular domain from invasive M3-type group a streptococcus shows significant similarity to immunomodulatory HIV protein gp41 (406 views)
Jbc Papers (ISSN: 0021-9258, 1083-351x, 0021-9258linking), 2014 Feb 21; 289(8): 5122-5133.
Impact Factor: 4.573
View Export to BibTeX Export to EndNote
Romanucci V, Milardi D, Campagna T, Gaglione M, Messere A, D'Urso A, Crisafi E, La Rosa C, Zarrelli A, Balzarini J, Di Fabio G
* Synthesis, biophysical characterization and anti-HIV activity of d(TG(3)AG) Quadruplexes bearing hydrophobic tails at the 5 '-end (365 views)
Bioorg Med Chem (ISSN: 0968-0896, 1464-3391, 0968-0896linking), 2014 Feb 1; 22(3): 960-966.
Impact Factor: 2.793
View Export to BibTeX Export to EndNote
Villari V, Attanasio F, Micali N
* Control of the structural stability of α-crystallin under thermal and chemical stress: The role of carnosine (410 views)
J Phys Chem B (ISSN: 1520-6106, 1520-5207, 1520-5207linking), 2014; 118(47): 13770-13776.
Impact Factor: 3.302
View Export to BibTeX Export to EndNote
Rami M, Dubois L, Parvathaneni NK, Alterio V, van Kuijk SJ, Monti SM, Lambin P, De Simone G, Supuran CT, Winum JY
* Hypoxia-targeting carbonic anhydrase IX inhibitors by a new series of nitroimidazole-sulfonamides/sulfamides/sulfamates (544 views)
J Med Chem (ISSN: 0022-2623, 1520-4804, 0022-2623print), 2013 Nov 14; 56(21): 8512-8520.
Impact Factor: 5.48
View Export to BibTeX Export to EndNote
Petruk AA, Varriale S, Coscia MR, Mazzarella L, Merlino A, Oreste U
* The Structure Of The Cd3 Zeta Zeta Transmembrane Dimer In Popc And Raft-Like Lipid Bilayer: A Molecular Dynamics Study (441 views)
Bba-Gen Subjects (ISSN: 0005-2736, 0006-3002e, 0005-2736print), 2013 Nov; 1828(11): 2637-2645.
Impact Factor: 3.498
View Export to BibTeX Export to EndNote
De Simone G, Alterio V, Supuran CT
* Exploiting the hydrophobic and hydrophilic binding sites for designing carbonic anhydrase inhibitors (507 views)
Expert Opin Drug Discov (ISSN: 1746-0441), 2013 Jul; 8(7): 793-810.
Impact Factor: 3.467
View Export to BibTeX Export to EndNote
Accardo A, Tesauro D, Morelli G
* Peptide-based targeting strategies for simultaneous imaging and therapy with nanovectors (483 views)
Polym J (ISSN: 0032-3896), 2013 May; 45(5): 481-493.
Impact Factor: 1.554
View Export to BibTeX Export to EndNote
Falciani C, Brunetti J, Lelli B, Accardo A, Tesauro D, Morelli G, Bracci L
* Nanoparticles exposing neurotensin tumor-specific drivers (448 views)
J Pept Sci (ISSN: 1075-2617, 1099-1387, 1075-2617print), 2013 Apr; 19(4): 198-204.
Impact Factor: 1.862
View Export to BibTeX Export to EndNote
Accardo A, Mangiapia G, Paduano L, Morelli G, Tesauro D
* Octreotide labeled aggregates containing platinum complexes as nanovectors for drug delivery (406 views)
J Pept Sci (ISSN: 1075-2617, 1099-1387, 1075-2617print), 2013 Apr; 19(4): 190-197.
Impact Factor: 1.862
View Export to BibTeX Export to EndNote
Attanasio F, Convertino M, Magno A, Caflisch A, Corazza A, Haridas H, Esposito G, Cataldo S, Pignataro B, Milardi D, Rizzarelli E
* Carnosine Inhibits Abeta(42) Aggregation By Perturbing The H-Bond Network In And Around The Central Hydrophobic Cluster (618 views)
Chembiochem (ISSN: 1439-4227, 1439-7633, 1439-7633electronic), 2013 Mar 18; 14(5): 583-592.
Impact Factor: 3.06
View Export to BibTeX Export to EndNote
Galdiero S, Falanga A, Tarallo R, Russo L, Galdiero E, Cantisani M, Morelli G, Galdiero M
* Peptide inhibitors against herpes simplex virus infections (782 views)
J Pept Sci (ISSN: 1075-2617, 1099-1387, 1075-2617print), 2013 Mar; 19(3): 148-158.
Impact Factor: 1.862
View Export to BibTeX Export to EndNote
Causa F, Della Moglie R, Iaccino E, Mimmi S, Marasco D, Scognamiglio PL, Battista E, Palmieri C, Cosenza C, Sanguigno L, Quinto I, Scala G, Netti PA
* Evolutionary screening and adsorption behavior of engineered M13 bacteriophage and derived dodecapeptide for selective decoration of gold interfaces (410 views)
J Colloid Interface Sci (ISSN: 0021-9797, 1095-7103electronic, 0021-9797linking), 2013 Jan 1; 389(1): 220-229.
Impact Factor: 1.646
View Export to BibTeX Export to EndNote
Accardo A, Ringhieri P, Tesauro D, Morelli G
* Liposomes derivatized with tetrabranched neurotensin peptides via click chemistry reactions (395 views)
New J Chem (ISSN: 1144-0546), 2013; 37(11): 3528-3534.
Impact Factor: 3.159
View Export to BibTeX Export to EndNote
Accardo A, Mansi R, Salzano G, Morisco A, Aurilio M, Parisi A, Maione F, Cicala C, Ziaco B, Tesauro D, Aloj L, De Rosa G, Morelli G
* Bombesin peptide antagonist for target-selective delivery of liposomal doxorubicin on cancer cells (410 views)
Journal Of Drug Targeting (ISSN: 1061-186x), 2012 Nov 21; 21(3): 240-249.
Impact Factor: 2.768
View Export to BibTeX Export to EndNote
Magrì A, D'Alessandro F, Di Stefano DA, Campagna T, Pappalardo G, Impellizzeri G, La Mendola D
* Copper(ii) Coordination Properties Of The Integrin Ligand Sequence Phsrn And Its New Beta-Cyclodextrin Conjugates (488 views)
Journal Of Inorganic Biochemistry, 2012 Sep; 113: 15-24.
Impact Factor: 3.444
View Export to BibTeX Export to EndNote
Sciacca MF, Chillemi R, Sciuto S, Pappalardo M, La Rosa C, Grasso D, Milardi D
* Interactions of two O-phosphorylresveratrol derivatives with model membranes (337 views)
Arch Biochem Biophys (ISSN: 1096-0384, 0003-3986), 2012 May; 521(1-2): 111-116.
Impact Factor: 0
View Export to BibTeX Export to EndNote
Cella L, Conson M, Caterino M, De Rosa N, Liuzzi R, Picardi M, Grimaldi F, Solla R, Farella A, Salvatore M, Pacelli R
* Thyroid V30 predicts radiation-induced hypothyroidism in patients treated with sequential chemo-radiotherapy for Hodgkin's lymphoma (489 views) (PDF 236 views)
Int J Radiat Oncol (ISSN: 0360-3016, 1879-355x, 1879-355xelectronic), 2012 Apr 1; 82(5): 1802-1808.
Impact Factor: 4.524
View Export to BibTeX Export to EndNote
Paola LD, Paci P, Santoni D, Ruvo MD, Giuliani A
* Proteins as sponges: A statistical journey along protein structure organization principles (402 views)
J Chem Inf Model (ISSN: 1549-9596), 2012 Feb 27; 52(2): 474-482.
Impact Factor: 4.304
View Export to BibTeX Export to EndNote
Falanga A, Tarallo R, Vitiello G, Vitiello M, Perillo E, Cantisani M, D'Errico G, Galdiero M, Galdiero S
* Biophysical Characterization and Membrane Interaction of the Two Fusion Loops of Glycoprotein B from Herpes Simplex Type I Virus (487 views)
Plosone (ISSN: 1932-6203, 1932-6203electronic, 1932-6203linking), 2012 Feb 23; 7(2): N/D-N/D.
Impact Factor: 3.73
View Export to BibTeX Export to EndNote
Merlino A, Vitiello G, Grimaldi M, Sica F, Busi E, Basosi R, D’Ursi A, Fragneto G, Paduano L, D’Errico G
* Destabilization of Lipid Membranes by a Peptide Derived from Glycoprotein gp36 of Feline Immunodeficiency Virus: A Combined Molecular Dynamics/Experimental Study (455 views)
J Phys Chem B (ISSN: 1520-6106, 1520-5207, 1520-5207electronic), 2012 Jan 12; 116(1): 401-412.
Impact Factor: 3.607
View Export to BibTeX Export to EndNote
Galdiero S, Vitiello M, Falanga A, Cantisani M, Incoronato N, Galdiero M
* Intracellular Delivery: Exploiting Viral Membranotropic Peptides (708 views)
Current Drug Metabolism (ISSN: 1389-2002), 2012 Jan; 13(1): 93-104.
Impact Factor: 4.405
View Export to BibTeX Export to EndNote
Accardo A, Salsano G, Morisco A, Aurilio M, Parisi A, Maione F, Cicala C, Tesauro D, Aloj L, De Rosa G, Morelli G
* Peptide-modified liposomes for selective targeting of bombesin receptors overexpressed by cancer cells: A potential theranostic agent (380 views)
Int J Nanomed (ISSN: 1176-9114, 1178-2013, 1178-2013electronic), 2012; 7: 2007-2017.
Impact Factor: 3.463
View Export to BibTeX Export to EndNote
Satriano C, Fragalà ME, Forte G, Santoro AM, La Mendola D, Kasemo B
* Surface adsorption of fibronectin-derived peptide fragments: The influence of electrostatics and hydrophobicity for endothelial cells adhesion (307 views)
Soft Matter (ISSN: 1744-683x), 2012; 8(1): 53-56.
Impact Factor: 3.909
View Export to BibTeX Export to EndNote
Tarallo R, Accardo A, Falanga A, Guarnieri D, Vitiello G, Netti P, D'Errico G, Morelli G, Galdiero S
* Clickable functionalization of liposomes with the gH625 peptide from herpes simplex virus type i for intracellular drug delivery (457 views)
Chemistry (ISSN: 0947-6539, 1521-3765, 1521-3765electronic), 2011 Nov 4; 17(45): 12659-12668.
Impact Factor: 5.925
View Export to BibTeX Export to EndNote
Cella L, Liuzzi R, Conson M, Torre G, Caterino M, De Rosa N, Picardi M, Camera L, Solla R, Farella A, Salvatore M, Pacelli R
* Dosimetric predictors of asymptomatic heart valvular dysfunction following mediastinal irradiation for Hodgkin's lymphoma (440 views)
Radiother Oncol (ISSN: 0167-8140, 1879-0887, 1879-0887electronic), 2011 Nov; 101(2): 316-321.
Impact Factor: 5.58
View Export to BibTeX Export to EndNote
Galdiero S, Falanga A, Vitiello M, Cantisani M, Marra V, Galdiero M
* Silver Nanoparticles as Potential Antiviral Agents (759 views)
Molecules (ISSN: 1420-3049, 1420-3049electronic, 1420-3049linking), 2011 Oct; 16(10): 8894-8918.
Impact Factor: 2.386
View Export to BibTeX Export to EndNote
Cuocolo A
Current research in nuclear medicine and molecular imaging in Italy: Highlights of the 10th National Congress of the Italian Association of Nuclear Medicine and Molecular Imaging (443 views)
Q J Nucl Med Mol Im (ISSN: 1824-4785, 1824-4478, 1824-4785linking), 2011 Jun; 55(3): 280-300.
Impact Factor: 1.724
View Export to BibTeX Export to EndNote
Monfregola L, Bugatti V, Amodeo P, De Luca S, Vittoria V
* Physical and Water Sorption Properties of Chemically Modified Pectin with an Environmentally Friendly Process (281 views)
Biomacromolecules (ISSN: 1525-7797), 2011 Jun; 12(6): 2311-2318.
Impact Factor: 5.479
View Export to BibTeX Export to EndNote
Falciani C, Accardo A, Brunetti J, Tesauro D, Lelli B, Pini A, Bracci L, Morelli G
* Target-Selective Drug Delivery through Liposomes Labeled with Oligobranched Neurotensin Peptides (529 views)
Chemmedchem (ISSN: 1860-7179, 1860-7187, 1860-7187electronic), 2011 Apr 4; 6(4): 678-685.
Impact Factor: 3.151
View Export to BibTeX Export to EndNote
Lusso P, Vangelista L, Cimbro R, Secchi M, Sironi F, Longhi R, Faiella M, Maglio O, Pavone V
* Molecular engineering of RANTES peptide mimetics with potent anti-HIV-1 activity (568 views)
Faseb J (ISSN: 0892-6638, 0892-6638linking), 2011 Apr; 25(4): 1230-1243.
Impact Factor: 5.712
View Export to BibTeX Export to EndNote
Accardo A, Morisco A, Gianolio E, Tesauro D, Mangiapia G, Radulescu A, Brandt A, Morelli G
* Nanoparticles containing octreotide peptides and gadolinium complexes for MRI applications (504 views)
J Pept Sci (ISSN: 1075-2617, 1099-1387, 1075-2617print), 2011 Feb; 17(2): 154-162.
Impact Factor: 1.799
View Export to BibTeX Export to EndNote
Accardo A, Morisco A, Tesauro D, Pedone C, Morelli G
* Naposomes: A new class of peptide-derivatized, target-selective multimodal nanoparticles for imaging and therapeutic applications (407 views)
Ther Deliv (ISSN: 2041-5990), 2011 Feb; 2(2): 235-257.
Impact Factor: 0
View Export to BibTeX Export to EndNote
Morisco A, Accardo A, Tesauro D, Palumbo R, Benedetti E, Morelli G
* Peptide-labeled supramolecular aggregates as selective doxorubicin carriers for delivery to tumor cells (360 views)
Biopolymers (ISSN: 0006-3525, 0006-6352, 0006-3525print), 2011; 96(1): 88-96.
Impact Factor: 2.87
View Export to BibTeX Export to EndNote
Strianese D, Tranfa F, Finelli M, De Renzo A, Staibano S, Schiemer R, Cardone D, Pacelli R, Perna F, Mascolo M, De Rosa G, Bonavolonta G
* Hepatitis C virus infection in ocular adnexal lymphomas (337 views)
Arch Ophthalmol (ISSN: 1538-3601, 0003-9950), 2010 Oct; 128(10): 1295-1299.
Impact Factor: 3.516
View Export to BibTeX Export to EndNote
Del Vecchio S, Zannetti A, Fonti R, Iommelli F, Pizzuti LM, Lettieri A, Salvatore M
* PET/CT in cancer research: From preclinical to clinical applications (617 views)
Contrast Media Mol Imaging (ISSN: 1555-4309, 1555-4309linking), 2010 Jul; 5(4): 190-200.
Impact Factor: 4.02
View Export to BibTeX Export to EndNote
Galdiero S, Falanga A, Vitiello M, Raiola L, Russo L, Pedone C, Isernia C, Galdiero M
* The presence of a single N-terminal histidine residue enhances the fusogenic properties of a Membranotropic peptide derived from herpes simplex virus type 1 glycoprotein (471 views)
Jbc Papers (ISSN: 1083-351x, 0021-9258, 0021-9258linking), 2010 May 28; 285(22): 17123-17136.
Impact Factor: 5.328
View Export to BibTeX Export to EndNote
Kelly SE, Di Benedetto A, Greco A, Howard CM, Sollars VE, Primerano DA, Valluri JV, Claudio PP
* Rapid Selection and Proliferation of CD133(+) Cells from Cancer Cell Lines: Chemotherapeutic Implications (454 views)
Plosone (ISSN: 1932-6203, 1932-6203electronic, 1932-6203linking), 2010 Apr 8; 5(4): N/D-N/D.
Impact Factor: 4.411
View Export to BibTeX Export to EndNote
Alberobello AT, D'Esposito V, Marasco D, Doti N, Ruvo M, Bianco R, Tortora G, Esposito I, Fiory F, Miele C, Beguinot F, Formisano P
* Selective Disruption of Insulin-like Growth Factor-1 (IGF-1) Signaling via Phosphoinositide-dependent Kinase-1 Prevents the Protective Effect of IGF-1 on Human Cancer Cell Death (578 views)
Jbc Papers (ISSN: 0021-9258, 1083-351x, 0021-9258linking), 2010 Feb 26; 285(9): 6563-6572.
Impact Factor: 5.328
View Export to BibTeX Export to EndNote
Satriano C, Messina GM, Marino C, Aiello I, Conte E, La Mendola D, Distefano DA, D'Alessandro F, Pappalardo G, Impellizzeri G
* Surface immobilization of fibronectin-derived PHSRN peptide on functionalized polymer films - Effects on fibroblast spreading (532 views)
J Colloid Interface Sci (ISSN: 1095-7103electronic, 0021-9797linking), 2010 Jan 15; 341(2): 232-239.
Impact Factor: 3.068
View Export to BibTeX Export to EndNote
Storto G, De Renzo A, Pellegrino T, Perna F, De Falco T, Erra P, Nardelli A, Speranza A, Klain M, Rotoli B, Pace L
* Assessment of Metabolic Response to Radioimmunotherapy with (90)Y-Ibritumomab Tiuxetan in Patients with Relapsed or Refractory B-Cell Non-Hodgkin Lymphoma (399 views)
Radiology (ISSN: 0033-8419, 1527-1315, 0033-8419linking), 2010 Jan; 254(1): 245-252.
Impact Factor: 6.069
View Export to BibTeX Export to EndNote
Puglisi A, Rizzarelli E, Vecchio G, Iacovino R, Benedetti E, Pedone C, Saviano M
* Crystal And Molecular Structure Of Beta-Cyclodextrins Functionalized With The Anti-Inflammatory Drug Etodolac (415 views)
Biopolymers (ISSN: 0006-3525, 0006-6352, 0006-3525print), 2009 Dec; 91(12): 1227-1235.
Impact Factor: 2.605
View Export to BibTeX Export to EndNote
Vitagliano L, Stanzione F, De Simone A, Esposito L
* Dynamics and Stability of Amyloid-Like Steric Zipper Assemblies with Hydrophobic Dry Interfaces (451 views)
Biopolymers (ISSN: 0006-3525, 0006-6352, 0006-3525print), 2009 Dec; 91(12): 1161-1171.
Impact Factor: 2.605
View Export to BibTeX Export to EndNote
D'Auria G, Vacatello M, Falcigno L, Paduano L, Mangiapia G, Calvanese L, Gambaretto R, Dettin M, Paolillo L
* Self-assembling properties of ionic-complementary peptides (483 views)
J Pept Sci (ISSN: 1075-2617, 1099-1387, 1075-2617print), 2009 Mar; 15(3): 210-219.
Impact Factor: 1.807
View Export to BibTeX Export to EndNote
Kaczmarek K, Farina B, Zubrzak P, Jankowski S, Zimecki M, Suder P, Benedetti E, Fattorusso R, Saviano M, Zabrocki J
* Synthesis, conformational analysis and immunological activity of β3Phe-substituted Cyclolinopeptide A analogues (460 views)
J Pept Sci (ISSN: 1075-2617, 1099-1387, 1075-2617print), 2009 Mar; 15(3): 166-174.
Impact Factor: 1.807
View Export to BibTeX Export to EndNote
Ruggiero A, Tizzano B, Pedone E, Pedone C, Wilmanns M, Berisio R
* Crystal Structure of the Resuscitation-Promoting Factor (Delta DUF)RpfB from M. tuberculosis (570 views)
J Mol Biol (ISSN: 0022-2836, 1089-8638, 1089-8638electronic), 2009 Jan 9; 385(1): 153-162.
Impact Factor: 3.871
View Export to BibTeX Export to EndNote
Vaccaro M, Mangiapia G, Accardo A, Tesauro D, Gianolio E, Frielinghaus H, Morelli G, Paduano L
* Polymerized mixed aggregates containing gadolinium complex and CCK8 peptide (377 views)
Colloid Polym Sci (ISSN: 0303-402x), 2008 Dec; 286(14-15): 1643-1652.
Impact Factor: 1.736
View Export to BibTeX Export to EndNote
Galdiero S, Falanga A, Vitiello M, Raiola L, Fattorusso R, Browne H, Pedone C, Isernia C, Galdiero M
* Analysis of a membrane interacting region of herpes simplex virus type 1 glycoprotein (544 views)
Jbc Papers (ISSN: 0021-9258, 1083-351x, 0021-9258linking), 2008 Oct 31; 283(44): 29993-30009.
Impact Factor: 5.52
View Export to BibTeX Export to EndNote
Sciacca MFM, Pappalardo M, Milardi D, Grasso DM, La Rosa C
* Calcium-Activated Membrane Interaction Of The Islet Amyloid Polypeptide: Implications In The Pathogenesis Of Type Ii Diabetes Mellitus (962 views)
Arch Biochem Biophys, 2008 Sep 15; 65(1-2): 291-298.
Impact Factor: 3.043
View Export to BibTeX Export to EndNote
Woo LWL, Fischer DS, Sharland CM, Trusselle M, Foster PA, Chander SK, Di Fiore A, Supuran CT, De Simone G, Purohit A, Reed MJ, Potter BVL
* Anticancer steroid sulfatase inhibitors: synthesis of a potent fluorinated second-generation agent, in vitro and in vivo activities, molecular modeling, and protein crystallography (643 views)
Mol Cancer Ther (ISSN: 1535-7163, 1538-8514electronic), 2008 Sep; 7(8): 2435-2444.
Impact Factor: 5.003
View Export to BibTeX Export to EndNote
Accardo A, Tesauro D, Del Pozzo L, Mangiapia G, Paduano L, Morelli G
* Micelles by self-assembling peptide-conjugate amphiphile: Synthesis and structural characterization (402 views)
J Pept Sci (ISSN: 1075-2617, 1099-1387, 1075-2617print), 2008 Sep; 14(8): 903-910.
Impact Factor: 1.654
View Export to BibTeX Export to EndNote
Hesse B, Lindhardt TB, Acampa W, Anagnostopoulos C, Ballinger J, Bax JJ, Edenbrandt L, Flotats A, Germano G, Stopar TG, Franken P, Kelion A, Kjaer A, Le Guludec D, Ljungberg M, Maenhout AF, Marcassa C, Marving J, Mckiddie F, Schaefer WM, Stegger L, Underw
* EANM/ESC guidelines for radionuclide imaging of cardiac function (569 views)
Eur J Nucl Med (ISSN: 1619-7070, 1619-7089, 0340-6997), 2008 Apr; 35(4): 851-885.
Impact Factor: 4.532
View Export to BibTeX Export to EndNote
Galdiero S, Vitiello M, D'Isanto M, Falanga A, Cantisani M, Browne H, Pedone C, Galdiero M
* The identification and characterization of fusogenic domains in herpes virus glycoprotein B molecules (460 views)
Chembiochem (ISSN: 1439-7633, 1439-4227, 1439-7633electronic), 2008 Mar 25; 9(5): 758-767.
Impact Factor: 3.322
View Export to BibTeX Export to EndNote
Malgieri G, Russo L, Esposito S, Baglivo I, Zaccaro L, Pedone EM, Di Blasio B, Isernia C, Pedone PV, Fattorusso R
* The Prokaryotic Cys2his2 Zinc Finger Domain Adopts A Novel Fold As Revealed By The Solution Structure Of Agrobacterium Tumefaciens Ros Dna Binding Domain (382 views)
P Natl Acad Sci Usa (ISSN: 0027-8424, 1091-6490, 0027-8424print), 2007 Oct 30; 104(44): 17341-17346.
Impact Factor: 9.598
View Export to BibTeX Export to EndNote
Calabrese V, Mancuso C, Calvani M, Rizzarelli E, Butterfield DA, Stella AM
* Nitric oxide in the central nervous system: neuroprotection versus neurotoxicity (698 views)
Nature Reviews Neuroscience (ISSN: 1471-0048), 2007 Oct; 8(10): 766-775.
Impact Factor: 24.52
View Export to BibTeX Export to EndNote
Tarantino G, Gentile A, Capone D, Basile V, Tarantino M, Di Minno MN, Cuocolo A, Conca P
* Does protracted antiviral therapy impact on HCV-related liver cirrhosis progression? (312 views)
World J Gastroentero (ISSN: 1007-9327, 2219-2840, 1007-9327linking), 2007 Sep 28; 13(36): 4903-4908.
Impact Factor: 2.433
View Export to BibTeX Export to EndNote
Galdiero S, Falanga A, Vitiello M, D'Isanto M, Collins C, Orrei V, Browne H, Pedone C, Galdiero M
* Evidence for a role of the membrane-proximal region of herpes simplex virus type 1 glycoprotein H in membrane fusion and virus inhibition (583 views)
Chembiochem (ISSN: 1439-4227, 1439-7633, 1439-7633electronic), 2007 May 25; 8(8): 885-895.
Impact Factor: 3.446
View Export to BibTeX Export to EndNote
Accardo A, Tesauro D, Mangiapia G, Pedone C, Morelli G
* Nanostructures by self-assembling peptide amphiphile as potential selective drug carriers (426 views)
Biopolymers (ISSN: 0006-3525, 0006-6352, 0006-3525print), 2007; 88(2): 115-121.
Impact Factor: 2.389
View Export to BibTeX Export to EndNote
Menchise V, De Simone G, Di Fiore A, Scozzafava A, Supuran CT
* Carbonic anhydrase inhibitors: X-ray crystallographic studies for the binding of 5-amino-1, 3, 4-thiadiazole-2-sulfonamide and 5-(4-amino-3-chloro-5-fluorophenylsulfonamido)1, 3, 4-thiadiazole-2-sulfon amide to human isoform II (308 views)
Bioorganic & Medicinal Chemistry Letters (ISSN: 0960-894x), 2006 Dec 15; 16(24): 6204-6208.
Impact Factor: 2.538
View Export to BibTeX Export to EndNote
Dalla Bona A, Formaggio F, Peggion C, Kaptein B, Broxterman Quirinus B, Galdiero S, Galdiero M, Vitiello M, Benedetti E, Toniolo C
* Synthesis, conformation, and bioactivity of novel analogues of the antiviral lipopeptide halovir (464 views)
J Pept Sci (ISSN: 1075-2617, 1099-1387, 1075-2617print), 2006 Dec; 12(12): 748-757.
Impact Factor: 1.801
View Export to BibTeX Export to EndNote
Calvanese L, Saporito A, Marasco D, D'Auria G, Minchiotti G, Pedone C, Paolillo L, Falcigno L, Ruvo M
* Solution structure of mouse Cripto CFC domain and its inactive variant Trp107Ala (379 views)
J Med Chem (ISSN: 0022-2623, 1520-4804, 0022-2623print), 2006 Nov 30; 49(24): 7054-7062.
Impact Factor: 5.115
View Export to BibTeX Export to EndNote
De Simone G, Vitale RM, Di Fiore A, Pedone C, Scozzafava A, Montero JL, Winum JY, Supuran CT
* Carbonic anhydrase inhibitors: Hypoxia-activatable sulfonamides incorporating disulfide bonds that target the tumor-associated isoform IX (473 views)
J Med Chem (ISSN: 0022-2623, 1520-4804, 0022-2623print), 2006 Sep 7; 49(18): 5544-5551.
Impact Factor: 5.115
View Export to BibTeX Export to EndNote
De Renzo A, Perna F, Persico M, Mainolfi C, Pace L
* 18F-fluorodeoxyglucose positron emission tomography/computed tomography in the evaluation of early response in a primary hepatic lymphoma (233 views)
Br J Haematol (ISSN: 0007-1048, 0007-1048linking, 1365-2141electronic), 2006 Jun; 133(6): 580-580.
Impact Factor: 4.498
View Export to BibTeX Export to EndNote
Cappiello M, Alterio V, Amodeo P, Del Corso A, Scaloni A, Pedone C, Moschini R, De Donatis GM, De Simone G, Mura U
* A new spot test for sulfhydryl-containing compounds (449 views)
Anal Biochem, 2006 Mar 14; 79(1-2): 610-611.
Impact Factor: 2.305
View Export to BibTeX Export to EndNote
Cappiello M, Alterio V, Amodeo P, Del Corso A, Scaloni A, Pedone C, Moschini R, De Donatis GM, De Simone G, Mura U
* Metal ion substitution in the catalytic site greatly affects the binding of sulfhydryl-containing compounds to leucyl aminopeptidase (691 views)
Biochemistry (ISSN: 0006-2960, 1520-4995, 1520-4995electronic), 2006 Mar 14; 45(10): 3226-3234.
Impact Factor: 3.633
View Export to BibTeX Export to EndNote
Mannini R, Rivieccio V, D'Auria S, Tanfani F, Ausili A, Pedone C, Grimaldi G, Facchiano A
* Structure/function of KRAB repression domains: Structural properties of KRAB modules inferred from hydrodynamic, circular dichroism, and FTIR spectroscopic analyses (552 views)
Proteins (ISSN: 0887-3585, 1097-0134, 1097-0134electronic), 2006 Feb 15; 62(3): 604-616.
Impact Factor: 3.73
View Export to BibTeX Export to EndNote
De Capua A, Goodman M, Amino Y, Saviano M, Benedetti E
* Conformation analysis of aspartame-based sweeteners by NMR spectroscopy, molecular dynamics simulations, and X-ray diffraction studies (613 views)
Chembiochem (ISSN: 1439-4227, 1439-7633, 1439-7633electronic), 2006 Feb; 7(2): 377-387.
Impact Factor: 4.1
View Export to BibTeX Export to EndNote
Di Fiore A, Pedone C, D'Ambrosio K, Scozzafava A, De Simone G, Supuran CT
* Carbonic anhydrase inhibitors: Valdecoxib binds to a different active site region of the human isoform II as compared to the structurally related cyclooxygenase II 'selective' inhibitor celecoxib (323 views)
Bioorg Med Chem Lett Bioorganic And Medicinal Chemistry Letters (ISSN: 0960-894x), 2006 Jan 15; 16(2): 437-442.
Impact Factor: 2.538
View Export to BibTeX Export to EndNote
Menchise V, De Simone G, Alterio V, Di Fiore A, Pedone C, Scozzafava A, Supuran CT
* Carbonic anhydrase inhibitors: Stacking with Phe131 determines active site binding region of inhibitors as exemplified by the X-ray crystal structure of a membrane-impermeant antitumor sulfonamide complexed with isozyme II (478 views)
J Med Chem (ISSN: 0022-2623, 1520-4804, 0022-2623print), 2005 Sep 8; 48(18): 5721-5727.
Impact Factor: 4.926
View Export to BibTeX Export to EndNote
Galdiero S, Falanga A, Vitiello M, Browne H, Pedone C, Galdiero M
* Fusogenic domains in herpes simplex virus type 1 glycoprotein (590 views)
Jbc Papers (ISSN: 0021-9258, 1083-351x, 0021-9258linking), 2005 Sep 5; 280(31): 28632-28643.
Impact Factor: 5.854
View Export to BibTeX Export to EndNote
Vacatello M, D'Auria G, Falcigno L, Dettin M, Gambaretto R, Di Bello C, Paolillo L
* Conformational Analysis Of Novel Heparin Binding Peptides (618 views)
Biomaterials (ISSN: 0142-9612, 1878-5905electronic, 0142-9612linking), 2005 Jun; 26(16): 3207-3214.
Impact Factor: 4.698
View Export to BibTeX Export to EndNote
Di Fiore A, De Simone G, Menchise V, Pedone C, Casini A, Scozzafava A, Supuran CT
* Carbonic anhydrase inhibitors: X-ray crystal structure of a benzenesulfonamide strong CA II and CA IX inhibitor bearing a pentafluorophenylaminothioureido tail in complex with isozyme II (489 views)
Bioorg Med Chem Lett Bioorganic And Medicinal Chemistry Letters (ISSN: 0960-894x), 2005 Apr 1; 15(7): 1937-1942.
Impact Factor: 2.478
View Export to BibTeX Export to EndNote
Di Natale G, Impellizzeri G, Pappalardo G
* Conformational properties of peptide fragments homologous to the 106-114 and 106-126 residues of the human prion protein: a CD and NMR spectroscopic study (419 views)
Org Biomol Chem (ISSN: 1477-0520, 1477-0539, 1477-0539electronic), 2005 Feb 7; 3(3): 490-497.
Impact Factor: 2.547
View Export to BibTeX Export to EndNote
Pappalardo M, Milardi D, La Rosa C, Zannoni C, Rizzarelli E, Grasso D
* A molecular dynamics study on the conformational stability of PrP 180-193 helix II prion fragment (306 views)
Chem Phys Lett (ISSN: 0009-2614), 2004 Jun 1; 390(4-6): 511-516.
Impact Factor: 2.438
View Export to BibTeX Export to EndNote
Accardo A, Tesauro D, Roscigno P, Gianolio E, Paduano L, D'Errico G, Pedone C, Morelli G
* Physicochemical Properties of Mixed Micellar Aggregates Containing CCK Peptides and Gd Complexes Designed as Tumor Specific Contrast Agents in MRI (452 views)
J Am Chem Soc (ISSN: 0002-7863, 0002-2786, 1520-5126), 2004 Mar 17; 126(10): 3097-3107.
Impact Factor: 6.903
View Export to BibTeX Export to EndNote
De Capua A, Del Gatto A, Zaccaro L, Saviano G, Carlucci A, Livigni A, Gedressi C, Tancredi T, Pedone C, Saviano M
* A synthetic peptide reproducing the mitochondrial targeting motif of AKAP121: A conformational study (460 views)
Biopolymers (ISSN: 0006-3525, 0006-6352, 0006-3525print), 2004; 76(6): 459-466.
Impact Factor: 2.863
View Export to BibTeX Export to EndNote
Galdiero S, Vitiello M, D'Isanto M, Di Niola E, Peluso L, Raieta K, Pedone C, Galdiero M, Benedetti E
* Induction of signaling pathways by herpes simplex virus type 1 through glycoprotein H peptides (589 views)
Biopolymers (ISSN: 0006-3525, 0006-6352, 0006-3525print), 2004; 76(6): 494-502.
Impact Factor: 2.863
View Export to BibTeX Export to EndNote
Mainenti PP, Romano L, Contegiacomo A, Romano M, Casella V, Cuccuru A, Insabato L, Salvatore M
* Rare diffuse peritoneal malignant neoplasms: CT findings in two cases (245 views)
Abdom Imaging (ISSN: 0942-8925, 1432-0509), 2003 Nov; 28(6): 827-830.
Impact Factor: 0.996
View Export to BibTeX Export to EndNote
Portella G, Pacelli R, Libertini S, Cella L, Vecchio G, Salvatore M, Fusco A
* ONYX-015 Enhances Radiation-Induced Death of Human Anaplastic Thyroid Carcinoma Cells (436 views)
J Clin Endocrinol Metab Journal Of Clinical Endocrinology And Metabolism (ISSN: 0021-972x), 2003 Oct 1; 88(10): 5027-5032.
Impact Factor: 5.873
View Export to BibTeX Export to EndNote
Tauchmanova L, De Rosa G, Serio B, Fazioli F, Mainolfi C, Lombardi G, Colao A, Salvatore M, Rotoli B, Selleri C
* Avascular necrosis in long-term survivors after allogeneic or autologous stem cell transplantation: A single center experience and a review (275 views)
Cancer (ISSN: 0008-543x), 2003 May 15; 97(10): 2453-2461.
Impact Factor: 2.045
View Export to BibTeX Export to EndNote
Grasso D, Milardi D, Guantieri V, La Rosa C, Rizzarelli E
* Interaction of prion peptide PrP 180-193 with DPPC model membranes: A thermodynamic study (383 views)
New J Chem (ISSN: 1144-0546), 2003; 27(2): 359-364.
Impact Factor: 2.272
View Export to BibTeX Export to EndNote
Acampa W, Petretta M, Cuocolo A
* Nuclear medicine procedures in cardiovascular diseases: An evidence based approach (466 views)
Q J Nucl Med (ISSN: 1124-3937, 1125-0135), 2002 Dec; 46(4): 323-330.
Impact Factor: 1.903
View Export to BibTeX Export to EndNote
Grasso D, Milardi D, La Rosa C, Impellizzeri G, Pappalardo G
* The interaction of a peptide with a scrambled hydrophobic/hydrophilic sequence (Pro-Asp-Ala-Asp-Ala-His-Ala-His-Ala-His-Ala-Ala-Ala-His-Gly) (PADH) with DPPC model membranes: A DSC study (274 views)
Thermochim Acta (ISSN: 0040-6031), 2002 Jul 15; 390(1-2): 73-78.
Impact Factor: 0.974
View Export to BibTeX Export to EndNote
Goodman M, Del Valle JR, Amino Y, Benedetti E
* Molecular basis of sweet taste in dipeptide taste ligands (245 views)
Pure Appl Chem (ISSN: 0033-4545), 2002; 74(7): 1109-1116.
Impact Factor: 1.75
View Export to BibTeX Export to EndNote
Masullo M, Cantiello P, Paola B, Fiengo A, Vitagliano L, Zagari A, Arcari P
* Valine114 Replacements In The Archaeal Elongation Factor 1a Enhanced Its Ability To Interact With Aminoacyl-Trna And Kirromycin (352 views)
Biochemistry (ISSN: 0006-2960, 1520-4995, 1520-4995electronic), 2002; 41(49): 14482-14488.
Impact Factor: 4.064
View Export to BibTeX Export to EndNote
De Simone G, Menchise V, Manco G, Mandrich L, Sorrentino N, Lang D, Rossi M, Pedone C
* The crystal structure of a hyper-thermophilic carboxylesterase from the archaeon Archaeoglobus fulgidus (422 views)
J Mol Biol (ISSN: 0022-2836, 1089-8638, 1089-8638electronic), 2001 Nov 30; 314(3): 507-518.
Impact Factor: 5.826
View Export to BibTeX Export to EndNote
Menchise V, Corbier C, Didierjean C, Saviano M, Benedetti E, Jacquot JP, Aubry A
* Crystal structure of the wild-type and D30A mutant thioredoxin h of Chlamydomonas reinhardtii and implications for the catalytic mechanism (405 views)
Biochem J (ISSN: 0264-6021, 1470-8728electronic, 0264-6021linking), 2001 Oct 1; 359(1): 65-75.
Impact Factor: 4.326
View Export to BibTeX Export to EndNote
Saviano G, Rossi F, Benedetti E, Pedone C, Mierke DF, Maione A, Zanotti G, Tancredi T, Saviano M
* Structural consequences of metal complexation of cyclo[Pro-Phe-Phe-Ala-Xaa]2 decapeptides (447 views)
Chemistry (ISSN: 0947-6539, 1521-3765, 1521-3765electronic), 2001 Mar 16; 7(6): 1176-1183.
Impact Factor: 4.614
View Export to BibTeX Export to EndNote
Grasso D, Milardi D, La Rosa C, Rizzarelli E
* DSC study of the interaction of the prion peptide PrP106-126 with artificial membranes (377 views)
New J Chem (ISSN: 1144-0546), 2001; 25(12): 1543-1548.
Impact Factor: 2.44
View Export to BibTeX Export to EndNote
Esposito L, Vitagliano L, Sica F, Sorrentino G, Zagari A, Mazzarella L
The ultrahigh resolution crystal structure of ribonuclease A containing an isoaspartyl residue: Hydration and sterochemical analysis (668 views)
J Mol Biol (ISSN: 0022-2836, 1089-8638, 1089-8638electronic), 2000 Mar 31; 297(3): 713-732.
Impact Factor: 5.388
View Export to BibTeX Export to EndNote
Levchenko A, Mehta B, Spengler BA, Narkar A, Fonti R, Biedler JL, Tsuruo T, Larson SM
Measurement of P-glycoprotein expression in multidrug-resistant human neuroblastoma cell lines using self-competitive binding assay (283 views)
Anal Biochem (ISSN: 0003-2697, 1096-0309electronic, 0003-2697linking), 1996 May 1; 236(2): 338-343.
Impact Factor: 2.017
View Export to BibTeX Export to EndNote
MAUREA S, LASTORIA S, CARACO C, INDOLFI P, CASALE F, DITULLIO M, SALVATORE M
IODINE-131-MIBG IMAGING TO MONITOR CHEMOTHERAPY RESPONSE IN ADVANCED NEUROBLASTOMA - COMPARISON WITH LABORATORY ANALYSIS (327 views)
J Nucl Med (ISSN: 0161-5505, 1535-5667, 1535-5667electronic), 1994 Sep; 35(9): 1429-1435.
Impact Factor: 3.491
View Export to BibTeX Export to EndNote
Correale P, Caraglia M, Pepe S, Ricciardi B, Barile C, Montagnani S, Pacelli R, Bianco A, Tagliaferri P
PHORBOL 12-MYRISTATE 13-ACETATE (PMA) INDUCES NEUROENDOCRINE-LIKE DIFFERENTIATION AND REVERSES DOXORUBICIN-RESISTANCE OF HUMAN COLON-CARCINOMA CELLS IN-VITRO (299 views)
Int J Oncol (ISSN: 1019-6439, 1791-2423electronic, 1019-6439linking), 1994 Feb; 4(2): 423-427.
Impact Factor: 1.181
View Export to BibTeX Export to EndNote
Di Blasio B, Pavone V, Nastri F, Isernia C, Saviano M, Pedone C, Cucinotta V, Impellizzeri G, Rizzarelli E, Vecchio G
Conformation for a β-cyclodextrin monosubstituted with a cyclic dipeptide (485 views)
P Natl Acad Sci Usa (ISSN: 0027-8424, 1091-6490, 0027-8424print), 1992 Sep 1; 89(15): 7218-7221.
Impact Factor: 9.04
View Export to BibTeX Export to EndNote
Scala S, Pacelli R, Iaffaioli RV, Normanno N, Pepe S, Frasci G, Genua G, Tsuruo T, Tagliaferri P, Bianco AR
Reversal of adriamycin resistance by recombinant α-interferon in multidrug-resistant human colon carcinoma LoVo-doxorubicin cells (559 views)
Cancer Res (ISSN: 0008-5472, 1538-7445, 1538-7445electronic), 1991 Sep 15; 51(18): 4898-4902.
Impact Factor: 8.426
View Export to BibTeX Export to EndNote
119 Records (116 excluding Abstracts).
Total impact factor: 451.646 (439.007 excluding Abstracts).
Total 5 year impact factor: 469.501 (455.772 excluding Abstracts).
Total impact factor: 451.646 (439.007 excluding Abstracts).
Total 5 year impact factor: 469.501 (455.772 excluding Abstracts).
513 views. Last view on Wednesday 01 February 2023, 20:16:12
ibb.cnr.it