Is the acromegalic cardiomyopathy reversible? Effect of 5-year normalization of growth hormone and insulin-like growth factor I levels on cardiac performance (314 views)
J Clin Endocrinol Metab (ISSN: 0021-972x), 2001 Apr; 86(4): 1551-1557.
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Paper type: Journal Article,
Impact factor: 5.16, 5-year impact factor: 1.273
Url: http://www.scopus.com/inward/record.url?eid=2-s2.0-0035040518&partnerID=40&md5=aefc9d728d974307efa3dd961aa4ef4c
Keywords: Growth Hormone, Octreotide, Somatomedin C, Acromegaly, Adult, Article, Cardiomyopathy, Clinical Article, Controlled Study, Disease Control, Exercise, Female, Heart Left Ventricle Ejection Fraction, Heart Performance, Heart Rate, Human, Priority Journal, Scintiangiography, Workload, Cardiomyopathies, Human Growth Hormone, Insulin-Like Growth Factor I, Middle Aged, Physical Endurance, Prospective Studies, Radionuclide Angiography, Stroke Volume, Time Factors,
Affiliations:
*** IBB - CNR ***
Departments of Molecular and Clinical Endocrinology and Oncology, Federico II University of Naples, 80131 Naples, Italy
Nuclear Medicine Center of the National Council of Research, Department of Biomorphological and Functional Sciences, Federico II University of Naples, 80131 Naples, Italy
Scientific Institute for Research and Care Neuromed, 86077 Pozzilli, Italy
Department of Molecular and Clinical Endocrinology and Oncology, Federico II University of Naples, via Sergio Pansini 5, 80131 Naples, Italy
References:
Nabarro, J.D.N., Acromegaly (1987) Clin Endocrinol, 26, pp. 481-51
Bengtsson, B.A., Edén, S., Ernest, I., Oden, A., Sjögren, B., Epidemiology and long term survival in acromegaly (1988) Acta Med Scand, 223, pp. 327-335
Bates, A.S., Van't Hoff, W., Jones, J.M., Clayton, R.N., An audit of outcome of treatment in acromegaly (1993) Q J Med, 86, pp. 293-299
Rajasoorya, C., Holdaway, I.M., Wrightson, P., Scott, D.J., Ibbertson, H.K., Determinants of clinical outcome and survival in acromegaly (1994) Clin Endocrinol, 41, pp. 95-102
Wright, A.D., Hill, D.M., Lowy, C., Russell Fraser, T., Mortality in acromegaly (1970) Q J Med, 153, pp. 1-16
Orme, S.M., McNally, R.J.Q., Cartwright, R.A., Belchetz, P.E., Mortality and cancer incidence in acromegaly: A retrospective cohort study (1998) J Clin Endocrinol Metab, 83, pp. 2730-2734
Saccà, L., Cittadini, A., Fazio, S., Growth hormone and the heart (1994) Endocr Rev, 15, pp. 555-573
Lombardi, G., Colao, A., Marzullo, P., Is growth hormone bad for your heart: Cardiovascular impact of GH deficiency and excess (1997) J Endocrinol, 155, pp. S33-S37
Colao, A., Merola, B., Ferone, D., Lombardi, G., Acromegaly (1997) J Clin Endocrinol Metab, 82, pp. 2777-2781
Minniti, G., Jaffrain-Rea, M.L., Moroni, C., Echocardiographic evidence for a direct effect of GH/IGF-I hypersecretion on cardiac mass and function in young acromegalics (1998) Clin Endocrinol, 49, pp. 101-106
Fazio, S., Cittadini, A., Biondi, B., Cardiovascular effects of short-term growth hormone hypersecretion (2000) J Clin Endocrinol Metab, 85, pp. 179-182
Bertoni, P.D., Morandi, G., Impaired left ventricular diastolic function in acromegaly: An echocardiographic study (1987) Acta Cardiol, 42, pp. 1-10
Rodrigues, E.A., Caruana, M.P., Lahiri, A., Nabarro, J.D.N., Jacobs, H.S., Raftery, E.B., Subclinical cardiac dysfunction in acromegaly: Evidence for a specific disease of heart muscle (1989) Br Heart J, 62, pp. 185-194
Sicolo, N., Bui, F., Sicolo, M., Acromegalic cardiopathy: A left ventricular scintigraphic study (1993) J Endocrinol Invest, 16, pp. 123-127
Cuocolo, A., Nicolai, A., Fazio, S., Impaired left ventricular diastolic filling in patients with acromegaly: Assessment with radionuclide angiography (1995) J Nucl Med, 36, pp. 196-201
Colao, A., Cuocolo, A., Marzullo, P., Impact of patient's age and disease duration on cardiac performance in acromegaly: A radionuclide angiography study (1999) J Clin Endocrinol Metab, 84, pp. 1518-1523
Colao, A., Baldelli, R., Marzullo, P., Systemic hypertension and impaired glucose tolerance are independently correlated to the severity of the acromegalic cardiomyopathy (2000) J Clin Endocrinol Metab, 85, pp. 193-199
Marzullo, P., Cuocolo, A., Ferone, D., Cardiac effect of thyrotoxicosis in acromegaly (2000) J Clin Endocrinol Metab, 85, pp. 1426-1432
López-Velasco, R., Escobar-Morreale, H.F., Vega, B., Cardiac involvement in acromegaly: Specific myocardiopathy or consequence of systemic hypertension (1997) J Clin Endocrinol Metab, 82, pp. 1047-1053
Thuesen, L., Christensen, S.E., Weeke, J., Ørskov, H., Henningsen, P., The cardiovascular effects of octreotide treatment in acromegaly: An echocardiographic study (1989) Clin Endocrinol, 30, pp. 619-625
Merola, B., Cittadini, A., Colao, A., Chronic treatment with the somatostatin analog octreotide improves cardiac abnormalities in acromegaly (1993) J Clin Endocrinol Metab, 77, pp. 790-793
Tokgözoglu, S.L., Erbas, T., Aytemir, K., Effects of octreotide on left ventricular mass in acromegaly (1994) Am J Cardiol, 74, pp. 1072-1074
Lira, M.J., Barkan, A.L., Buda, A.J., Rapid reduction of left ventricular hypertrophy in acromegaly after suppression of growth hormone hypersecretion (1992) Ann Intern Med, 117, pp. 719-726
Baldelli, R., Ferretti, E., Jaffrain-Rea, M.L., Cardiac effects of lanreotide, a slow release somatostafin analog, in acromegalic patients (1999) J Clin Endocrinol Metab, 84, pp. 575-532
Hradec, J., Kral, J., Janota, T., Regression of acromegalic left ventricular hypertrophy after lanreotide (a slow release somatostatin analog) (1999) Am J Cardiol, 83, pp. 1506-1509
Chanson, P., Timsit, J., Masquet, C., Cardiovascular effects of the somatostatin analog octreotide in acromegaly (1990) Ann Intern Med, 113, pp. 921-925
Colao, A., Lombardi, G., Growth-hormone and prolactin excess (1998) Lancet, 352, pp. 1455-1461
Giustina, A., Barkan, A., Casanueva, F.F., Criteria for cure of acromegaly: A consensus statement (2000) J Clin Endocrinol Metab, 85, pp. 526-529
Hypertension control. Report of a WHO expert committee (1996) WHO Tech Rep Ser, 862, pp. 1-83
Colao, A., Ferone, D., Lastoria, S., Prediction of efficacy of octreotide therapy in patients with acromegaly (1996) J Clin Endocrinol Metab, 81, pp. 2356-2362
Bonow, R.O., Bacharach, S.L., Green, M.V., Impaired left ventricular diastolic filling in patients with coronary artery disease: Assessment with radionuclide angiography (1981) Circulation, 64, pp. 315-323
Cuocolo, A., Sax, F.L., Brush, J.E., Maron, B.J., Bacharach, S.L., Bonow, R.O., Left ventricular hypertrophy and impaired diastolic filling in essential hypertension (1990) Circulation, 81, pp. 978-986
Cuocolo, A., Storto, G., Izzo, R., Effects of valsartan on left ventricular diastolic function in patients with mild or moderate essential hypertension: Comparison with enalapril (1999) J Hypertens, 17, pp. 1759-1766
Huchard, H., Anatomie pathologique, lesions et trouble cardiovasculaires de l'acromegalie (1895) J Practiciens, 9, pp. 249-250
Swearingen, B., Barker II, F.G., Katznelson, L., Long-term mortality after transsphenoidal surgery and adjunctive therapy for acromegaly (1998) J Clin Endocrinol Metab, 83, pp. 3419-3426
Freda, P.U., Wardlaw, S.L., Post, K.D., Long-term endocrinological follow-up evaluation in 115 patients who underwent transsphenoidal surgery for acromegaly (1998) J Neurosurg, 89, pp. 353-358
Melmed, S., Dowling, R.H., Frohman, L.A., Consensus statement: Benefits versus risks of medical therapy for acromegaly (1994) Am J Med, 97, pp. 468-473
Lamberts, S.W.J., Van der Lely, A.-J., De Herder, W.W., Hofland, L.J., Octreotide (1996) N Engl J Med, 34, pp. 246-254
Feigenbaum, H., (1979) Echocardiography, ed. 2, , Philadelphia: Lea and Febiger
Tsukahara, H., Gordienko, D.V., Tonshoff, B., Gelato, M.C., Goligorsky, M.S., Direct demonstration of insulin-like growth factor I induced nitric oxide production by endothelial cells (1994) Kidney Int, 45, pp. 598-604
Böger, R.H., Skamira, C., Bode-Böger, S.M., Brabant, C., Von Zur Muhlen, A., Frolich, J.C., Nitric oxide mediates the hemodynamic effects of recombinant growth hormone in patients with acquired growth hormone deficiency (1996) J Clin Invest, 98, pp. 2706-2713
Gunal, A.I., Isik, A., Celiker, H., Short term reduction of left ventricular mass in primary hypertrophic cardiomyopathy by octreotide injections (1996) Heart, 76, pp. 418-421
Demirtas, E., Sag, C., Kursaklioglu, H., Effects of octreotide in patients with hypertrophic obstructive cardiomyopathy (1998) Jpn Heart J, 39, pp. 173-181
Crick, S.J., Sheppard, M.N., Ho, S.Y., Anderson, R.H., Localisation and quantitation of autonomic innervation in the porcine heart I: Conduction system (1999) J Anat, 195, pp. 341-357
Nabarro, J. D. N., Acromegaly (1987) Clin Endocrinol, 26, pp. 481-51
Bengtsson, B. A., Ed n, S., Ernest, I., Oden, A., Sj gren, B., Epidemiology and long term survival in acromegaly (1988) Acta Med Scand, 223, pp. 327-335
Bates, A. S., Van't Hoff, W., Jones, J. M., Clayton, R. N., An audit of outcome of treatment in acromegaly (1993) Q J Med, 86, pp. 293-299
Wright, A. D., Hill, D. M., Lowy, C., Russell Fraser, T., Mortality in acromegaly (1970) Q J Med, 153, pp. 1-16
Orme, S. M., McNally, R. J. Q., Cartwright, R. A., Belchetz, P. E., Mortality and cancer incidence in acromegaly: A retrospective cohort study (1998) J Clin Endocrinol Metab, 83, pp. 2730-2734
Sacc, L., Cittadini, A., Fazio, S., Growth hormone and the heart (1994) Endocr Rev, 15, pp. 555-573
Bertoni, P. D., Morandi, G., Impaired left ventricular diastolic function in acromegaly: An echocardiographic study (1987) Acta Cardiol, 42, pp. 1-10
Rodrigues, E. A., Caruana, M. P., Lahiri, A., Nabarro, J. D. N., Jacobs, H. S., Raftery, E. B., Subclinical cardiac dysfunction in acromegaly: Evidence for a specific disease of heart muscle (1989) Br Heart J, 62, pp. 185-194
L pez-Velasco, R., Escobar-Morreale, H. F., Vega, B., Cardiac involvement in acromegaly: Specific myocardiopathy or consequence of systemic hypertension (1997) J Clin Endocrinol Metab, 82, pp. 1047-1053
Tokg zoglu, S. L., Erbas, T., Aytemir, K., Effects of octreotide on left ventricular mass in acromegaly (1994) Am J Cardiol, 74, pp. 1072-1074
Lira, M. J., Barkan, A. L., Buda, A. J., Rapid reduction of left ventricular hypertrophy in acromegaly after suppression of growth hormone hypersecretion (1992) Ann Intern Med, 117, pp. 719-726
Bonow, R. O., Bacharach, S. L., Green, M. V., Impaired left ventricular diastolic filling in patients with coronary artery disease: Assessment with radionuclide angiography (1981) Circulation, 64, pp. 315-323
Freda, P. U., Wardlaw, S. L., Post, K. D., Long-term endocrinological follow-up evaluation in 115 patients who underwent transsphenoidal surgery for acromegaly (1998) J Neurosurg, 89, pp. 353-358
Lamberts, S. W. J., Van der Lely, A. -J., De Herder, W. W., Hofland, L. J., Octreotide (1996) N Engl J Med, 34, pp. 246-254
B ger, R. H., Skamira, C., Bode-B ger, S. M., Brabant, C., Von Zur Muhlen, A., Frolich, J. C., Nitric oxide mediates the hemodynamic effects of recombinant growth hormone in patients with acquired growth hormone deficiency (1996) J Clin Invest, 98, pp. 2706-2713
Gunal, A. I., Isik, A., Celiker, H., Short term reduction of left ventricular mass in primary hypertrophic cardiomyopathy by octreotide injections (1996) Heart, 76, pp. 418-421
Crick, S. J., Sheppard, M. N., Ho, S. Y., Anderson, R. H., Localisation and quantitation of autonomic innervation in the porcine heart I: Conduction system (1999) J Anat, 195, pp. 341-357
J Clin Endocrinol Metab (ISSN: 0021-972x), 2001 Apr; 86(4): 1551-1557.
Export to BibTeX Export to EndNote
Paper type: Journal Article,
Impact factor: 5.16, 5-year impact factor: 1.273
Url: http://www.scopus.com/inward/record.url?eid=2-s2.0-0035040518&partnerID=40&md5=aefc9d728d974307efa3dd961aa4ef4c
Keywords: Growth Hormone, Octreotide, Somatomedin C, Acromegaly, Adult, Article, Cardiomyopathy, Clinical Article, Controlled Study, Disease Control, Exercise, Female, Heart Left Ventricle Ejection Fraction, Heart Performance, Heart Rate, Human, Priority Journal, Scintiangiography, Workload, Cardiomyopathies, Human Growth Hormone, Insulin-Like Growth Factor I, Middle Aged, Physical Endurance, Prospective Studies, Radionuclide Angiography, Stroke Volume, Time Factors,
Affiliations:
*** IBB - CNR ***
Departments of Molecular and Clinical Endocrinology and Oncology, Federico II University of Naples, 80131 Naples, Italy
Nuclear Medicine Center of the National Council of Research, Department of Biomorphological and Functional Sciences, Federico II University of Naples, 80131 Naples, Italy
Scientific Institute for Research and Care Neuromed, 86077 Pozzilli, Italy
Department of Molecular and Clinical Endocrinology and Oncology, Federico II University of Naples, via Sergio Pansini 5, 80131 Naples, Italy
References:
Nabarro, J.D.N., Acromegaly (1987) Clin Endocrinol, 26, pp. 481-51
Bengtsson, B.A., Edén, S., Ernest, I., Oden, A., Sjögren, B., Epidemiology and long term survival in acromegaly (1988) Acta Med Scand, 223, pp. 327-335
Bates, A.S., Van't Hoff, W., Jones, J.M., Clayton, R.N., An audit of outcome of treatment in acromegaly (1993) Q J Med, 86, pp. 293-299
Rajasoorya, C., Holdaway, I.M., Wrightson, P., Scott, D.J., Ibbertson, H.K., Determinants of clinical outcome and survival in acromegaly (1994) Clin Endocrinol, 41, pp. 95-102
Wright, A.D., Hill, D.M., Lowy, C., Russell Fraser, T., Mortality in acromegaly (1970) Q J Med, 153, pp. 1-16
Orme, S.M., McNally, R.J.Q., Cartwright, R.A., Belchetz, P.E., Mortality and cancer incidence in acromegaly: A retrospective cohort study (1998) J Clin Endocrinol Metab, 83, pp. 2730-2734
Saccà, L., Cittadini, A., Fazio, S., Growth hormone and the heart (1994) Endocr Rev, 15, pp. 555-573
Lombardi, G., Colao, A., Marzullo, P., Is growth hormone bad for your heart: Cardiovascular impact of GH deficiency and excess (1997) J Endocrinol, 155, pp. S33-S37
Colao, A., Merola, B., Ferone, D., Lombardi, G., Acromegaly (1997) J Clin Endocrinol Metab, 82, pp. 2777-2781
Minniti, G., Jaffrain-Rea, M.L., Moroni, C., Echocardiographic evidence for a direct effect of GH/IGF-I hypersecretion on cardiac mass and function in young acromegalics (1998) Clin Endocrinol, 49, pp. 101-106
Fazio, S., Cittadini, A., Biondi, B., Cardiovascular effects of short-term growth hormone hypersecretion (2000) J Clin Endocrinol Metab, 85, pp. 179-182
Bertoni, P.D., Morandi, G., Impaired left ventricular diastolic function in acromegaly: An echocardiographic study (1987) Acta Cardiol, 42, pp. 1-10
Rodrigues, E.A., Caruana, M.P., Lahiri, A., Nabarro, J.D.N., Jacobs, H.S., Raftery, E.B., Subclinical cardiac dysfunction in acromegaly: Evidence for a specific disease of heart muscle (1989) Br Heart J, 62, pp. 185-194
Sicolo, N., Bui, F., Sicolo, M., Acromegalic cardiopathy: A left ventricular scintigraphic study (1993) J Endocrinol Invest, 16, pp. 123-127
Cuocolo, A., Nicolai, A., Fazio, S., Impaired left ventricular diastolic filling in patients with acromegaly: Assessment with radionuclide angiography (1995) J Nucl Med, 36, pp. 196-201
Colao, A., Cuocolo, A., Marzullo, P., Impact of patient's age and disease duration on cardiac performance in acromegaly: A radionuclide angiography study (1999) J Clin Endocrinol Metab, 84, pp. 1518-1523
Colao, A., Baldelli, R., Marzullo, P., Systemic hypertension and impaired glucose tolerance are independently correlated to the severity of the acromegalic cardiomyopathy (2000) J Clin Endocrinol Metab, 85, pp. 193-199
Marzullo, P., Cuocolo, A., Ferone, D., Cardiac effect of thyrotoxicosis in acromegaly (2000) J Clin Endocrinol Metab, 85, pp. 1426-1432
López-Velasco, R., Escobar-Morreale, H.F., Vega, B., Cardiac involvement in acromegaly: Specific myocardiopathy or consequence of systemic hypertension (1997) J Clin Endocrinol Metab, 82, pp. 1047-1053
Thuesen, L., Christensen, S.E., Weeke, J., Ørskov, H., Henningsen, P., The cardiovascular effects of octreotide treatment in acromegaly: An echocardiographic study (1989) Clin Endocrinol, 30, pp. 619-625
Merola, B., Cittadini, A., Colao, A., Chronic treatment with the somatostatin analog octreotide improves cardiac abnormalities in acromegaly (1993) J Clin Endocrinol Metab, 77, pp. 790-793
Tokgözoglu, S.L., Erbas, T., Aytemir, K., Effects of octreotide on left ventricular mass in acromegaly (1994) Am J Cardiol, 74, pp. 1072-1074
Lira, M.J., Barkan, A.L., Buda, A.J., Rapid reduction of left ventricular hypertrophy in acromegaly after suppression of growth hormone hypersecretion (1992) Ann Intern Med, 117, pp. 719-726
Baldelli, R., Ferretti, E., Jaffrain-Rea, M.L., Cardiac effects of lanreotide, a slow release somatostafin analog, in acromegalic patients (1999) J Clin Endocrinol Metab, 84, pp. 575-532
Hradec, J., Kral, J., Janota, T., Regression of acromegalic left ventricular hypertrophy after lanreotide (a slow release somatostatin analog) (1999) Am J Cardiol, 83, pp. 1506-1509
Chanson, P., Timsit, J., Masquet, C., Cardiovascular effects of the somatostatin analog octreotide in acromegaly (1990) Ann Intern Med, 113, pp. 921-925
Colao, A., Lombardi, G., Growth-hormone and prolactin excess (1998) Lancet, 352, pp. 1455-1461
Giustina, A., Barkan, A., Casanueva, F.F., Criteria for cure of acromegaly: A consensus statement (2000) J Clin Endocrinol Metab, 85, pp. 526-529
Hypertension control. Report of a WHO expert committee (1996) WHO Tech Rep Ser, 862, pp. 1-83
Colao, A., Ferone, D., Lastoria, S., Prediction of efficacy of octreotide therapy in patients with acromegaly (1996) J Clin Endocrinol Metab, 81, pp. 2356-2362
Bonow, R.O., Bacharach, S.L., Green, M.V., Impaired left ventricular diastolic filling in patients with coronary artery disease: Assessment with radionuclide angiography (1981) Circulation, 64, pp. 315-323
Cuocolo, A., Sax, F.L., Brush, J.E., Maron, B.J., Bacharach, S.L., Bonow, R.O., Left ventricular hypertrophy and impaired diastolic filling in essential hypertension (1990) Circulation, 81, pp. 978-986
Cuocolo, A., Storto, G., Izzo, R., Effects of valsartan on left ventricular diastolic function in patients with mild or moderate essential hypertension: Comparison with enalapril (1999) J Hypertens, 17, pp. 1759-1766
Huchard, H., Anatomie pathologique, lesions et trouble cardiovasculaires de l'acromegalie (1895) J Practiciens, 9, pp. 249-250
Swearingen, B., Barker II, F.G., Katznelson, L., Long-term mortality after transsphenoidal surgery and adjunctive therapy for acromegaly (1998) J Clin Endocrinol Metab, 83, pp. 3419-3426
Freda, P.U., Wardlaw, S.L., Post, K.D., Long-term endocrinological follow-up evaluation in 115 patients who underwent transsphenoidal surgery for acromegaly (1998) J Neurosurg, 89, pp. 353-358
Melmed, S., Dowling, R.H., Frohman, L.A., Consensus statement: Benefits versus risks of medical therapy for acromegaly (1994) Am J Med, 97, pp. 468-473
Lamberts, S.W.J., Van der Lely, A.-J., De Herder, W.W., Hofland, L.J., Octreotide (1996) N Engl J Med, 34, pp. 246-254
Feigenbaum, H., (1979) Echocardiography, ed. 2, , Philadelphia: Lea and Febiger
Tsukahara, H., Gordienko, D.V., Tonshoff, B., Gelato, M.C., Goligorsky, M.S., Direct demonstration of insulin-like growth factor I induced nitric oxide production by endothelial cells (1994) Kidney Int, 45, pp. 598-604
Böger, R.H., Skamira, C., Bode-Böger, S.M., Brabant, C., Von Zur Muhlen, A., Frolich, J.C., Nitric oxide mediates the hemodynamic effects of recombinant growth hormone in patients with acquired growth hormone deficiency (1996) J Clin Invest, 98, pp. 2706-2713
Gunal, A.I., Isik, A., Celiker, H., Short term reduction of left ventricular mass in primary hypertrophic cardiomyopathy by octreotide injections (1996) Heart, 76, pp. 418-421
Demirtas, E., Sag, C., Kursaklioglu, H., Effects of octreotide in patients with hypertrophic obstructive cardiomyopathy (1998) Jpn Heart J, 39, pp. 173-181
Crick, S.J., Sheppard, M.N., Ho, S.Y., Anderson, R.H., Localisation and quantitation of autonomic innervation in the porcine heart I: Conduction system (1999) J Anat, 195, pp. 341-357
Nabarro, J. D. N., Acromegaly (1987) Clin Endocrinol, 26, pp. 481-51
Bengtsson, B. A., Ed n, S., Ernest, I., Oden, A., Sj gren, B., Epidemiology and long term survival in acromegaly (1988) Acta Med Scand, 223, pp. 327-335
Bates, A. S., Van't Hoff, W., Jones, J. M., Clayton, R. N., An audit of outcome of treatment in acromegaly (1993) Q J Med, 86, pp. 293-299
Wright, A. D., Hill, D. M., Lowy, C., Russell Fraser, T., Mortality in acromegaly (1970) Q J Med, 153, pp. 1-16
Orme, S. M., McNally, R. J. Q., Cartwright, R. A., Belchetz, P. E., Mortality and cancer incidence in acromegaly: A retrospective cohort study (1998) J Clin Endocrinol Metab, 83, pp. 2730-2734
Sacc, L., Cittadini, A., Fazio, S., Growth hormone and the heart (1994) Endocr Rev, 15, pp. 555-573
Bertoni, P. D., Morandi, G., Impaired left ventricular diastolic function in acromegaly: An echocardiographic study (1987) Acta Cardiol, 42, pp. 1-10
Rodrigues, E. A., Caruana, M. P., Lahiri, A., Nabarro, J. D. N., Jacobs, H. S., Raftery, E. B., Subclinical cardiac dysfunction in acromegaly: Evidence for a specific disease of heart muscle (1989) Br Heart J, 62, pp. 185-194
L pez-Velasco, R., Escobar-Morreale, H. F., Vega, B., Cardiac involvement in acromegaly: Specific myocardiopathy or consequence of systemic hypertension (1997) J Clin Endocrinol Metab, 82, pp. 1047-1053
Tokg zoglu, S. L., Erbas, T., Aytemir, K., Effects of octreotide on left ventricular mass in acromegaly (1994) Am J Cardiol, 74, pp. 1072-1074
Lira, M. J., Barkan, A. L., Buda, A. J., Rapid reduction of left ventricular hypertrophy in acromegaly after suppression of growth hormone hypersecretion (1992) Ann Intern Med, 117, pp. 719-726
Bonow, R. O., Bacharach, S. L., Green, M. V., Impaired left ventricular diastolic filling in patients with coronary artery disease: Assessment with radionuclide angiography (1981) Circulation, 64, pp. 315-323
Freda, P. U., Wardlaw, S. L., Post, K. D., Long-term endocrinological follow-up evaluation in 115 patients who underwent transsphenoidal surgery for acromegaly (1998) J Neurosurg, 89, pp. 353-358
Lamberts, S. W. J., Van der Lely, A. -J., De Herder, W. W., Hofland, L. J., Octreotide (1996) N Engl J Med, 34, pp. 246-254
B ger, R. H., Skamira, C., Bode-B ger, S. M., Brabant, C., Von Zur Muhlen, A., Frolich, J. C., Nitric oxide mediates the hemodynamic effects of recombinant growth hormone in patients with acquired growth hormone deficiency (1996) J Clin Invest, 98, pp. 2706-2713
Gunal, A. I., Isik, A., Celiker, H., Short term reduction of left ventricular mass in primary hypertrophic cardiomyopathy by octreotide injections (1996) Heart, 76, pp. 418-421
Crick, S. J., Sheppard, M. N., Ho, S. Y., Anderson, R. H., Localisation and quantitation of autonomic innervation in the porcine heart I: Conduction system (1999) J Anat, 195, pp. 341-357
Is the acromegalic cardiomyopathy reversible? Effect of 5-year normalization of growth hormone and insulin-like growth factor I levels on cardiac performance
Acromegalic patients are considered to be exposed to a doubled mortality rate, mostly for cardiovascular diseases. This open prospective study was designed to evaluate whether the impairment of cardiac performance could be reversed by the long-term suppression of GH and insulin-like growth factor I (IGF-I) levels. Eighteen patients with active acromegaly were studied before and 5 yr after surgery, followed by sc octreotide in 11 patients. Disease control (GH levels ≤1 μg/L after glucose load or ≤2.5 μg/L after fasting, respectively, together with normalized IGF-I levels for age) was achieved in seven patients after surgery and in six patients after 0.3-0.6 mg/day sc octreotide. Five patients were not controlled during the 5-yr follow-up. Cardiac performance at rest and at peak exercise was assessed by equilibrium radionuclide angiography at study entry and 5 yr after surgery alone or plus octreotide. Thirty-six sex- and age-matched healthy subjects served as controls. At study entry, patients had a lower left ventricular ejection fraction (LVEF) at peak exercise and LVEF exercise-induced changes, exercise duration, and capacity than controls (P < 0.001). After 5 yr of treatment, a significant decrease of resting heart rate (P = 0.03) and a significant increase of LVEF at peak exercise (P = 0.003) was found in patients achieving disease control. LVEF response at peak exercise worsened in none of the patients with controlled disease and in three patients with uncontrolled disease (60%) (x2 = 5.5; P = 0.02). Diastolic filling, exercise duration, and workload did not significantly change during the 5-yr follow-up. No difference was found between patients controlled by surgery alone or by surgery plus octreotide. This 5-yr prospective study demonstrated that the LVEF response at peak exercise improved in all patients achieving disease control, while it was worsened in 60% of uncontrolled ones. These results strengthen the need of a stable suppression of GH and IGF-I hyper-secretion to restore a normal cardiac performance in acromegaly.
Acromegalic patients are considered to be exposed to a doubled mortality rate, mostly for cardiovascular diseases. This open prospective study was designed to evaluate whether the impairment of cardiac performance could be reversed by the long-term suppression of GH and insulin-like growth factor I (IGF-I) levels. Eighteen patients with active acromegaly were studied before and 5 yr after surgery, followed by sc octreotide in 11 patients. Disease control (GH levels ≤1 μg/L after glucose load or ≤2.5 μg/L after fasting, respectively, together with normalized IGF-I levels for age) was achieved in seven patients after surgery and in six patients after 0.3-0.6 mg/day sc octreotide. Five patients were not controlled during the 5-yr follow-up. Cardiac performance at rest and at peak exercise was assessed by equilibrium radionuclide angiography at study entry and 5 yr after surgery alone or plus octreotide. Thirty-six sex- and age-matched healthy subjects served as controls. At study entry, patients had a lower left ventricular ejection fraction (LVEF) at peak exercise and LVEF exercise-induced changes, exercise duration, and capacity than controls (P < 0.001). After 5 yr of treatment, a significant decrease of resting heart rate (P = 0.03) and a significant increase of LVEF at peak exercise (P = 0.003) was found in patients achieving disease control. LVEF response at peak exercise worsened in none of the patients with controlled disease and in three patients with uncontrolled disease (60%) (x2 = 5.5; P = 0.02). Diastolic filling, exercise duration, and workload did not significantly change during the 5-yr follow-up. No difference was found between patients controlled by surgery alone or by surgery plus octreotide. This 5-yr prospective study demonstrated that the LVEF response at peak exercise improved in all patients achieving disease control, while it was worsened in 60% of uncontrolled ones. These results strengthen the need of a stable suppression of GH and IGF-I hyper-secretion to restore a normal cardiac performance in acromegaly.
Is the acromegalic cardiomyopathy reversible? Effect of 5-year normalization of growth hormone and insulin-like growth factor I levels on cardiac performance
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Is the acromegalic cardiomyopathy reversible? Effect of 5-year normalization of growth hormone and insulin-like growth factor I levels on cardiac performance
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* Cardiovascular consequences of early-onset growth hormone excess (419 views)
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Impact Factor: 5.199
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Manganelli F, Betocchi S, Ciampi Q, Storto G, Losi MA, Violante A, Briguori C, Tocchetti CG, Lombardi R, Cuocolo A, Chiariello M
* Myopia and IOP (401 views)
Ann Ottalmol Clin Ocul, 2002 Jun 15; 115(10): 1053-1058.
Impact Factor: 0
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Colao A, Di Somma C, Pivonello R, Cuocolo A, Spinelli L, Bonaduce D, Salvatore M, Lombardi G
* The cardiovascular risk of adult GH deficiency (GHD) improved after GH replacement and worsened in untreated GHD: A 12-month prospective study (378 views)
J Clin Endocrinol Metab (ISSN: 0021-972x), 2002 Mar; 87(3): 1088-1093.
Impact Factor: 5.199
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Colao A, Di Somma C, Cuocolo A, Spinelli L, Tedesco N, Pivonello R, Bonaduce D, Salvatore M, Lombardi G
* Improved cardiovascular risk factors and cardiac performance after 12 months of growth hormone (GH) replacement in young adult patients, with GH deficiency (443 views)
J Clin Endocrinol Metab (ISSN: 0021-972x), 2001 May; 86(5): 1874-1881.
Impact Factor: 5.16
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Colao A, Marzullo P, Ferone D, Spinelli L, Cuocolo A, Bonaduce D, Salvatore M, Boerlin V, Lancranjan I, Lombardi G
Cardiovascular effects of depot long-acting somatostatin analog sandostatin LAR in acromegaly (427 views)
J Clin Endocrinol Metab (ISSN: 0021-972x), 2000 Sep; 85(9): 3132-3140.
Impact Factor: 5.447
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Marzullo P, Cuocolo A, Ferone D, Pivonello R, Salvatore M, Lombardi G, Colao A
Cardiac effect of thyrotoxicosis in acromegaly (479 views)
J Clin Endocrinol Metab (ISSN: 0021-972x), 2000 Apr; 85(4): 1426-1432.
Impact Factor: 5.447
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Colao A, Cuocolo A, Di Somma C, Cerbone G, Della Morte A, Pivonello R, Nicolai E, Salvatore M, Lombardi G
Does the age of onset of growth hormone deficiency affect cardiac performance? A radionuclide angiography study (303 views)
Clin Endocrinol (ISSN: 0300-0664, 1365-2265, 1365-2265electronic), 2000 Apr; 52(4): 447-455.
Impact Factor: 2.922
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Clampi Q, Losi M, Violante A, Manganelli F, Pezzella E, Storto G, Tocchetti C, Finizio F, Lombardi R, Briguori C, Cuocolo A, Betocchi S
Effects of isometric exercise in obstructive hypertrophic cardiomyopathy (253 views)
Circulationcirculation (ISSN: 0009-7322), 1999 Nov 2; 100(18SUPPL.): N/D-N/D.
Impact Factor: 9.903
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Colao A, Cuocolo A, Di Somma C, Cerbone G, Della Morte A, Nicolai E, Lucci R, Salvatore M, Lombardi G
Impaired cardiac performance in elderly patients with growth hormone deficiency (329 views)
J Clin Endocrinol Metab (ISSN: 0021-972x), 1999 Nov; 84(11): 3950-3955.
Impact Factor: 5.805
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Manganelli F, Betocchi S, Ciampi Q, Losi MA, Tocchetti GC, Cuocolo A, Storto G, Violante A, Lombardi R, Chiariello M
Haemodynamic determinants of syncope in hypertrophic cardiomyopathy (243 views)
European Heart Journal (ISSN: 0195-668x), 1999 Sep; 20(ABSTR.SUPPL.): N/D-N/D.
Impact Factor: 3.21
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Colao A, Cuocolo A, Marzullo P, Nicolai E, Ferone D, Della Morte A, Petretta M, Salvatore M, Lombardi G
Impact of patient's age and disease duration on cardiac performance in acromegaly: A radionuclide angiography study (287 views)
J Clin Endocrinol Metab (ISSN: 0021-972x), 1999 May; 84(5): 1518-1523.
Impact Factor: 5.805
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Colao A, Lastoria S, Ferone D, Varrella P, Marzullo P, Pivonello R, Cerbone G, Acampa W, Salvatore M, Lombardi G
The pituitary uptake of In-111-DTPA-D-Phe(1)-octreotide in the normal pituitary and in pituitary adenomas (387 views)
J Endocrinol Invest (ISSN: 0391-4097, 1720-8386electronic), 1999 Mar; 22(3): 176-183.
Impact Factor: 0.957
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Colao A, Cuocolo A, Marzullo P, Nicolai E, Ferone D, Florimonte L, Salvatore M, Lombardi G
Effects of 1-year treatment with octreotide on cardiac performance in patients with acromegaly (364 views)
J Clin Endocrinol Metab (ISSN: 0021-972x), 1999 Jan; 84(1): 17-23.
Impact Factor: 5.805
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Lastoria S, Vergara E, Palmieri G, Acampa W, Varrella P, Caracò C, Bianco RA, Muto P, Salvatore M
In vivo detection of malignant thymic masses by indium-111-DTPA-D- Phe1-octreotide scintigraphy (428 views)
J Nucl Med (ISSN: 0161-5505, 1535-5667, 1535-5667electronic), 1998 Apr; 39(4): 634-639.
Impact Factor: 3.064
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Longobardi S, Cuocolo A, Merola B, Di Rella F, Colao A, Nicolai E, Cardei S, Salvatore M, Lombardi G
Left ventricular function in young adults with childhood and adulthood onset growth hormone deficiency (434 views)
Clin Endocrinol (ISSN: 0300-0664, 1365-2265, 1365-2265electronic), 1998 Feb; 48(2): 137-143.
Impact Factor: 3.101
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Ferone D, Lastoria S, Colao A, Varrella P, Cerbone G, Acampa W, Merola B, Salvatore M, Lombardi G
Correlation of scintigraphic results using 123I-methoxybenzamide with hormone levels and tumor size response to quinagolide in patients with pituitary adenomas (316 views)
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Impact Factor: 5.641
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Lombardi G, Colao A, Cuocolo A, Longobardi S, Di Somma C, Orio F, Merola B, Nicolai E, Salvatore M
Cardiological aspects of growth hormone and insulin-like growth factor- (437 views)
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Impact Factor: 0.481
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Maurea S, Lastoria S, Caracò C, Klain M, Varrella P, Acampa W, Muto P, Salvatore M
The role of radiolabeled somatostatin analogs in adrenal imaging (358 views)
Nucl Med Biol (ISSN: 0969-8051, 0883-2897), 1996 Sep; 23(6): 677-680.
Impact Factor: 1.042
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Lastoria S, Maurea S, Vergara E, Acampa W, Varrella P, Klain M, Muto P, Bernardy JD, Salvatore M
Comparison of labeled MIBG and somatostatin analogs in imaging neuroendocrine tumors (336 views)
Q J Nucl Med (ISSN: 1125-0135, 1124-3937), 1995 Dec; 39(4Suppl1): 145-149.
Impact Factor: 2.125
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Cuocolo A, Nicolai E, Fazio S, Pace L, Maurea S, Cittadini A, Sacca L, Salvatore M
Impaired left ventricular diastolic filling in patients with acromegaly: Assessment with radionuclide angiography (261 views)
J Nucl Med (ISSN: 0161-5505, 1535-5667, 1535-5667electronic), 1995 Feb; 36(2): 196-201.
Impact Factor: 3.491
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Palmeieri G, Lastoria S, Vergara E, Varrella P, Acampa W, Salvatore M, Bianco AR
Diagnosis and treatment of thymoma by octreotide (234 views)
Meetingproceedings Of The American Association For Cancer Research Annual (ISSN: 0197-016x), 1995; 36(0): N/D-N/D.
Impact Factor: 0
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LASTORIA S, COLAO A, VERGARA E, FERONE D, VARRELLA P, MEROLA B, ACAMPA W, LOMBARDI G, SALVATORE M
IN-111 OCTREOTIDE UPTAKE LEVELS IN PITUITARY-ADENOMAS TO PREDICT THE RESPONSIVENESS TO CHRONIC OCTREOTIDE TREATMENT (240 views)
J Nucl Med (ISSN: 0161-5505, 1535-5667, 1535-5667electronic), 1994 May; 35(5): N/D-N/D.
Impact Factor: 3.491
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LASTORIA S, VERGARA E, VARRELLA P, ACAMPA W, PALMIERI G, SALVATORE M
IN-VIVO DETECTION OF NEW DISEASES EXPRESSING SOMATOSTATIN RECEPTORS BY IN-111 OCTREOTIDE (267 views)
J Nucl Med (ISSN: 0161-5505, 1535-5667, 1535-5667electronic), 1994 May; 35(5): N/D-N/D.
Impact Factor: 3.491
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LASTORIA S, VERGARA E, VARRELLA P, ACAMPA W, PALMIERI G, SALVATORE M
IN-VIVO DETECTION OF NEW NEOPLASTIC LESIONS EXPRESSING SOMATOSTATIN RECEPTORS USING IN-111 OCTREOTIDE (293 views)
Posters Tomes 1 4proceedings Of The Xvi International Cancer Congress Free Papers And, 1994; N/D: N/D-N/D.
Impact Factor: 0
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Nappi A, Cuocolo A, Nicolai E, Imbriaco M, Pace L, Salvatore M
Ambulatory monitoring of left ventricular function with a radionuclide detector system (295 views)
Radiol Med (ISSN: 0033-8362, 1826-6983, 1826-6983electronic), 1992; 84(1-2): 132-139.
Impact Factor: 0.967
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Pezzino V, Papa V, Trischitta V, Brunetti A, Goodman PA, Treutelaar MK, Williams JA, Maddux BA, Vigneri R, Goldfine ID
Human insulin receptor radioimmunoassay: Applicability to insulin-resistant states (263 views)
Am J Physiol Endocrinol Metab (ISSN: 0002-9513), 1989 Sep; 257(3): N/D-N/D.
Impact Factor: 3.116
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* Exercise triggers CAPN1-mediated AIF truncation, inducing myocyte cell death in arrhythmogenic cardiomyopathy (165 views)
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Impact Factor: 17.956
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Lanzillo R, Di Somma C, Quarantelli M, Carotenuto A, Pivonello C, Moccia M, Cianflone A, Marsili A, Puorro G, Sacca F, Russo CV, De Luca Picione C, Ausiello F, Colao A, Brescia Morra V
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Impact Factor: 4.621
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Pisani A, Sabbatini M, Imbriaco M, Riccio E, Rubis N, Prinster A, Perna A, Liuzzi R, Spinelli L, Santangelo M, Remuzzi G, Ruggenenti P
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Perrino C, Imbriaco M, Magliulo F, Ponsiglione A, Puglia M, Stabile E, Avvedimento M, Esposito G, Perrone Filardi P, Cuocolo A, Galderisi M, Trimarco B
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Impact Factor: 6.189
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De Luca S, Fonti R, Camera L, Salvatore B, Faggiano A, Ciarmiello A, Segreto S, Colao A, Salvatore M, Del Vecchio S
* Multimodal imaging with (18)F-FDG-PET/CT and (111)In-Octreotide SPECT in patients with metastatic medullary thyroid carcinoma (332 views)
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Impact Factor: 1.396
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Giuffrida ML, Tomasello MF, Pandini G, Caraci F, Battaglia G, Busceti C, Di Pietro P, Pappalardo G, Attanasio F, Chiechio S, Bagnoli S, Nacmias B, Sorbi S, Vigneri R, Rizzarelli E, Nicoletti F, Copani A
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Ruggiero L, Fiorillo C, Tessa A, Manganelli F, Iodice R, Dubbioso R, Vitale F, Storti E, Soscia E, Santorelli F, Santoro L
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Impact Factor: 2.713
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Ramundo V, Del Prete M, Marotta V, Marciello F, Camera L, Napolitano V, de LucaL, Circelli L, Colantuoni V, Di Sarno A, Carratu AC, Di Roseto CDL, Colao A, Faggiano A
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Impact Factor: 3.457
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Petretta M, Pellegrino T, Cuocolo A
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J Nucl Cardiol (ISSN: 1071-3581, 1532-6551, 1532-6551electronic), 2014; 21(5): 921-924.
Impact Factor: 2.942
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Milardi D, Sciacca MF, Randazzo L, Raudino A, La Rosa C
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Impact Factor: 3.675
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Dynkevich Y, Rother KI, Whitford I, Qureshi S, Galiveeti S, Szulc AL, Danoff A, Breen TL, Kaviani N, Shanik MH, LeRoith D, Vigneri R, Koch CA, Roth J
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Impact Factor: 19.358
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Ferro A, Petretta M, Acampa W, Fiumara G, Daniele S, Petretta MP, Cantoni V, Cuocolo A
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Impact Factor: 1.5
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Fonti R, Mainolfi C, Anzivino A, Camera L, Faggiano A, Colao A, Salvatore M, Del Vecchio S
* 18F-FDG-PET/CT and 111In-Octreotide SPECT in Patients with Metastatic Medullary Thyroid Carcinoma (270 views)
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Impact Factor: 5.217
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Pellegrino T, Petretta M, Paolillo S, Boemio A, Carotenuto R, Petretta MP, Di Nuzzo C, Perrone-filardi P, Cuocolo A
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Impact Factor: 5.217
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Accardo A, Mangiapia G, Paduano L, Morelli G, Tesauro D
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J Pept Sci (ISSN: 1075-2617, 1099-1387, 1075-2617print), 2013 Apr; 19(4): 190-197.
Impact Factor: 1.862
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De Luca S, Fonti R, Palmieri G, Federico P, Del Prete G, Pacelli R, Pace L, De Placido S, Salvatore M, Del Vecchio S
* Combined Imaging With 18f-Fdg-Pet/Ct And 111in-Labeled Octreotide Spect For Evaluation Of Thymic Epithelial Tumors (349 views)
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Impact Factor: 2.857
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Giuffrida ML, Tomasello F, Caraci F, Chiechio S, Nicoletti F, Copani A
* Beta-Amyloid monomer and insulin/IGF-1 signaling in Alzheimer's disease (1006 views)
Mol Neurobiol (ISSN: 0893-7648), 2012 Dec; 46(3): 605-613.
Impact Factor: 5.471
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Palmieri G, Fonti R, Federico P, Del Prete G, Pacelli R, Pace L, Salvatore M, Del Vecchio S
* Combined 18F-FDG-PET/CT and 111In-Octreotide SPECT for Evaluation of Thymic Epithelial Tumors (271 views)
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Impact Factor: 5.114
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Saccà F, Quarantelli M, Rinaldi C, Tucci T, Piro R, Perrotta G, Carotenuto B, Marsili A, Palma V, De Michele G, Brunetti A, Brescia Morra V, Filla A, Salvatore M
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Impact Factor: 3.578
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Perrone-Filardi P, Paolillo S, Dellegrottaglie S, Gargiulo P, Savarese G, Marciano C, Casaretti L, Cecere M, Musella F, Pirozzi E, Parente A, Cuocolo A
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Impact Factor: 4.223
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Accardo A, Morisco A, Gianolio E, Tesauro D, Mangiapia G, Radulescu A, Brandt A, Morelli G
* Nanoparticles containing octreotide peptides and gadolinium complexes for MRI applications (504 views)
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Impact Factor: 1.799
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Nardelli A, Castaldi E, Ortosecco G, Speranza A, Storto G, Pace L, Salvatore M
* Enhancement of reaction conditions for the radiolabelling of DOTA-peptides with high activities of yttrium-90 (468 views)
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Impact Factor: 1.172
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Lanzillo R, Di Somma C, Quarantelli M, Ventrella G, Vacca G, Liuzzi R, Amato L, Orefice G, Colao A, Brescia Morra V
* Growth Hormone Axis In Early Multiple Sclerosis Patients Before And After 2 Years Treatment With Interferon Beta-1b - An Interim Analysis (275 views)
Proceedings Of The Xlii Meeting Of The Italian Society Of Neurology, 2011; nd: 360-360.
Impact Factor: 0
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Imbriaco M, Messalli G, Avitabile G, Cuocolo A, Maurea S, Soscia F, Pisani A
* Cardiac magnetic resonance imaging illustrating Anderson-Fabry disease progression (283 views)
Br J Radiol (ISSN: 0007-1285, 1748-880xelectronic, 0007-1285linking), 2010 Dec; 83(996): e249-e249.
Impact Factor: 2.062
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Alberobello AT, D'Esposito V, Marasco D, Doti N, Ruvo M, Bianco R, Tortora G, Esposito I, Fiory F, Miele C, Beguinot F, Formisano P
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Jbc Papers (ISSN: 0021-9258, 1083-351x, 0021-9258linking), 2010 Feb 26; 285(9): 6563-6572.
Impact Factor: 5.328
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Giuffrida ML, Caraci F, Pignataro B, Cataldo S, De Bona P, Bruno V, Molinaro G, Pappalardo G, Messina A, Palmigiano A, Garozzo D, Nicoletti F, Rizzarelli E, Copani A
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Impact Factor: 3.669
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Storto G, Nicolai E, Petretta M, Spinelli L, Acampa W, Evangelista L, Daniele S, Trimarco B, Cuocolo A
* Cardiac performance during exercise in hypertensive patients without ventricular hypertrophy (392 views)
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Impact Factor: 2.643
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Cittadini A, Saldamarco L, Marra AM, Arcopinto M, Carlomagno G, Imbriaco M, Del Forno D, Vigorito C, Merola B, Oliviero U, Fazio S, Sacca L
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Impact Factor: 6.202
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Sacca F, Quarantelli M, Rinaldi C, Tucci T, Piro R, Carotenuto B, Marsili A, Palma V, Bresciamorra V, Brunetti A, De Michele G, Filla A, Salvatore M
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Impact Factor: 8.172
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Sacca F, Quarantelli M, Rinaldi C, Tucci T, Piro R, Carotenuto B, Marsili A, Palma V, Bresciamorra V, Brunetti A, De Michele G, Filla A, Salvatore M
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Impact Factor: 8.172
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Morisco A, Accardo A, Gianolio E, Tesauro D, Benedetti E, Morelli G
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Impact Factor: 1.807
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Zaccaro L, Del Gatto A, Pedone C, Saviano M
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Impact Factor: 4.708
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Cittadini A, Monti MG, Castiello MC, D'Arco E, Galasso G, Sorriento D, Saldamarco L, De Paulis A, Napoli R, Iaccarino G, Saccà L
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Impact Factor: 6.069
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Spinelli L, Nicolai E, Acampa W, Imbriaco M, Pisani A, Rao MA, Scopacasa F, Cianciaruso B, De Luca N, Cuocolo A
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Impact Factor: 2.784
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Supuran CT, Di Fiore A, De Simone G
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Expert Opin Emerg Drugsexpert Opinion On Emerging Drugs (ISSN: 1472-8214), 2008 Jun; 13(2): 383-392.
Impact Factor: 3.08
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Pulcrano M, Camera L, Pagano L, Del Vecchio S, Ferone D, Bodei L, Murgia A, Pace L, Storto G, Paganelli G, Colao A, Salvatore M, Lombardi G, Biondi B
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Impact Factor: 1.888
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De Simone G, Di Fiore A, Supuran CT
* Are carbonic anhydrase inhibitors suitable for obtaining antiobesity drugs? (472 views)
Curr Pharm Des Current Pharmaceutical Design (ISSN: 1381-6128, 1873-4286), 2008 Mar; 14(7): 655-660.
Impact Factor: 4.399
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Migliore T, Parrella LS, Caputi A, Silvestri N, Romano R, Pace L, Imbriaco M, Losi MA, Betocchi S
* Pathogenesis of hypertrophic cardiomyopathy. Impact of growth factors on left ventricular anatomy (367 views)
Minerva Cardioangiol (ISSN: 0026-4725), 2008 Feb; 56(1): 13-20.
Impact Factor: 0.481
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Frasca F, Pandini G, Sciacca L, Pezzino V, Squatrito S, Belfiore A, Vigneri R
* The role of insulin receptors and IGF-I receptors in cancer and other diseases (1583 views)
Archives Of Physiology And Biochemistry (ISSN: 1381-3455), 2008 Feb; 114(1): 23-37.
Impact Factor: 2.028
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Ciampi Q, Betocchi S, Losi MA, Ferro A, Cuocolo A, Lombardi R, Villari B, Chiariello M
* Abnormal blood-pressure response to exercise and oxygen consumption in patients with hypertrophic cardiomyopathy (335 views)
J Nucl Cardiol (ISSN: 1532-6551, 1071-3581, 1532-6551electronic), 2007 Nov; 14(6): 869-875.
Impact Factor: 2.359
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Colao A, Di Somma C, Cuocolo A, Spinelli L, Acampa W, Spiezia S, Rota F, Savanelli MC, Lombardi G
* Does a gender-related effect of growth hormone (GH) replacement exist on cardiovascular risk factors, cardiac morphology, and performance and atherosclerosis? Results of a two-year open, prospective study in young adult men and women with severe GH deficiency (422 views)
J Clin Endocrinol Metab (ISSN: 0021-972x), 2005 Sep; 90(9): 5146-5155.
Impact Factor: 6.02
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Tauchmanovà L, Pensabene M, Capuano I, Spagnoletti I, Zeppa P, Del Vecchio S, Mainenti PP, De Rosa G, Colao A, Contegiacomo A
* Poorly differentiated small cell neuroendocrine carcinoma localized in three different endocrine glands: Response to chemotherapy and octreotide LAR (328 views)
J Endocrinol Invest (ISSN: 0391-4097, 1720-8386electronic), 2005 Apr; 28(4): 371-378.
Impact Factor: 1.496
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Savastano S, Pivonello R, Acampa W, Salvatore M, Lombardi G, Colao A, Fenzi G
* Recombinant thyrotropin-induced orbital uptake of [In-111-diethylenetriamine-pentacetic acid-D-phe(1)]octreotide in a patient with inactive Graves' ophthalmopathy (308 views)
Journal Of Clinical Endocrinology & Metabolism (ISSN: 0021-972x), 2005 Apr; 90(4): 2440-2444.
Impact Factor: 6.02
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Santomauro M, Pace L, Duilio C, Ottaviano L, Borrelli A, Ferro A, Monteforte N, Cuocolo A, Salvatore M, Chiariello M
* Left ventricular pacing in patients with heart failure: Evaluation study with Fourier analysis of radionuclide ventriculography (274 views)
Ital Heart J (ISSN: 1129-471x), 2004 Dec; 5(12): 906-911.
Impact Factor: 6.023
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Colao A, Di Somma C, Cuocolo A, Filippella M, Rota F, Acampa W, Savastano S, Salvatore M, Lombardi G
* The severity of growth hormone deficiency correlates with the severity of cardiac impairment in 100 adult patients with hypopituitarism: An observational, case-control study (283 views)
J Clin Endocrinol Metab (ISSN: 0021-972x), 2004 Dec; 89(12): 5998-6004.
Impact Factor: 5.778
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Spinelli L, Petretta M, Verderame G, Carbone G, Venetucci AA, Petretta A, Acampa W, Bonaduce D, Colao A, Cuocolo A
* Left ventricular diastolic function and cardiac performance during exercise in patients with acromegaly (433 views)
J Clin Endocrinol Metab (ISSN: 0021-972x), 2003 Sep; 88(9): 4105-4109.
Impact Factor: 5.873
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Ciampi Q, Betocchi S, Violante A, Lombardi R, Losi M, Storto G, Manganelli F, Tocchetti C, Aversa M, Pezzella E, Finizio F, Cuocolo A, Chiariello M
* Hemodynamic effects of isometric exercise in hypertrophic cardiomyopathy: Comparison with normal subjects (403 views)
J Nucl Cardiol (ISSN: 1071-3581, 1532-6551, 1532-6551electronic), 2003 Mar; 10(2): 154-160.
Impact Factor: 1.629
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Colao A, Marzullo P, Cuocolo A, Spinelli L, Pivonello R, Bonaduce D, Salvatore M, Lombardi G
* Reversal of acromegalic cardiomyopathy in young but not in middle-aged patients after 12 months of treatment with the depot long-acting somatostatin analogue octreotide (429 views)
Clin Endocrinol (ISSN: 0300-0664, 1365-2265, 1365-2265electronic), 2003 Feb; 58(2): 169-176.
Impact Factor: 2.767
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Camera L, Del Vecchio S, Quarantelli M, Ibello F, Pellegrino T, Salvatore M
* Radiolabeled somatostatin analogs in the diagnosis and staging of neuroendocrine tumors (329 views)
J Endocrinol Invest (ISSN: 0391-4097, 1720-8386electronic), 2003; 26(8Suppl): 60-62.
Impact Factor: 1.621
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Petretta M, Vicario ML, Spinelli L, Ferro A, Cuocolo A, Condorelli M, Bonaduce D
* Combined effect of the force-frequency and length-tension mechanisms on left ventricular function in patients with dilated cardiomyopathy (314 views)
Eur J Heart Fail European Journal Of Heart Failure (ISSN: 1388-9842), 2002 Dec; 4(6): 727-735.
Impact Factor: 2.134
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Acampa W, Petretta M, Cuocolo A
* Nuclear medicine procedures in cardiovascular diseases: An evidence based approach (467 views)
Q J Nucl Med (ISSN: 1124-3937, 1125-0135), 2002 Dec; 46(4): 323-330.
Impact Factor: 1.903
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Ciampi Q, Betocchi S, Lombardi R, Losi M, Manganelli F, Storto G, Aversa M, Miranda M, Cuocolo A, Tocchetti CG, Chiariello M
* The diastolic function in hypertrophic cardiomyopathy (208 views)
Cardiologia, 2002 Nov 5; 33(8): 741-746.
Impact Factor: 0
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Ciampi Q, Betocchi S, Lombardi R, Manganelli F, Storto G, Losi MA, Pezzella E, Finizio F, Cuocolo A, Chiariello M
* Hemodynamic determinants of exercise-induced abnormal blood pressure response in hypertrophic cardiomyopathy (289 views)
Journal Of The American College Of Cardiology (ISSN: 0735-1097), 2002 Jul 17; 40(2): 278-284.
Impact Factor: 6.278
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Colao A, Spinelli L, Cuocolo A, Spiezia S, Pivonello R, Di Somma C, Bonaduce D, Salvatore M, Lombardi G
* Cardiovascular consequences of early-onset growth hormone excess (419 views)
J Clin Endocrinol Metab (ISSN: 0021-972x), 2002 Jul; 87(7): 3097-3104.
Impact Factor: 5.199
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Manganelli F, Betocchi S, Ciampi Q, Storto G, Losi MA, Violante A, Briguori C, Tocchetti CG, Lombardi R, Cuocolo A, Chiariello M
* Myopia and IOP (401 views)
Ann Ottalmol Clin Ocul, 2002 Jun 15; 115(10): 1053-1058.
Impact Factor: 0
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Colao A, Di Somma C, Pivonello R, Cuocolo A, Spinelli L, Bonaduce D, Salvatore M, Lombardi G
* The cardiovascular risk of adult GH deficiency (GHD) improved after GH replacement and worsened in untreated GHD: A 12-month prospective study (378 views)
J Clin Endocrinol Metab (ISSN: 0021-972x), 2002 Mar; 87(3): 1088-1093.
Impact Factor: 5.199
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Colao A, Di Somma C, Cuocolo A, Spinelli L, Tedesco N, Pivonello R, Bonaduce D, Salvatore M, Lombardi G
* Improved cardiovascular risk factors and cardiac performance after 12 months of growth hormone (GH) replacement in young adult patients, with GH deficiency (443 views)
J Clin Endocrinol Metab (ISSN: 0021-972x), 2001 May; 86(5): 1874-1881.
Impact Factor: 5.16
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Colao A, Marzullo P, Ferone D, Spinelli L, Cuocolo A, Bonaduce D, Salvatore M, Boerlin V, Lancranjan I, Lombardi G
Cardiovascular effects of depot long-acting somatostatin analog sandostatin LAR in acromegaly (427 views)
J Clin Endocrinol Metab (ISSN: 0021-972x), 2000 Sep; 85(9): 3132-3140.
Impact Factor: 5.447
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Marzullo P, Cuocolo A, Ferone D, Pivonello R, Salvatore M, Lombardi G, Colao A
Cardiac effect of thyrotoxicosis in acromegaly (479 views)
J Clin Endocrinol Metab (ISSN: 0021-972x), 2000 Apr; 85(4): 1426-1432.
Impact Factor: 5.447
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Colao A, Cuocolo A, Di Somma C, Cerbone G, Della Morte A, Pivonello R, Nicolai E, Salvatore M, Lombardi G
Does the age of onset of growth hormone deficiency affect cardiac performance? A radionuclide angiography study (303 views)
Clin Endocrinol (ISSN: 0300-0664, 1365-2265, 1365-2265electronic), 2000 Apr; 52(4): 447-455.
Impact Factor: 2.922
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Clampi Q, Losi M, Violante A, Manganelli F, Pezzella E, Storto G, Tocchetti C, Finizio F, Lombardi R, Briguori C, Cuocolo A, Betocchi S
Effects of isometric exercise in obstructive hypertrophic cardiomyopathy (253 views)
Circulationcirculation (ISSN: 0009-7322), 1999 Nov 2; 100(18SUPPL.): N/D-N/D.
Impact Factor: 9.903
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Colao A, Cuocolo A, Di Somma C, Cerbone G, Della Morte A, Nicolai E, Lucci R, Salvatore M, Lombardi G
Impaired cardiac performance in elderly patients with growth hormone deficiency (329 views)
J Clin Endocrinol Metab (ISSN: 0021-972x), 1999 Nov; 84(11): 3950-3955.
Impact Factor: 5.805
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Manganelli F, Betocchi S, Ciampi Q, Losi MA, Tocchetti GC, Cuocolo A, Storto G, Violante A, Lombardi R, Chiariello M
Haemodynamic determinants of syncope in hypertrophic cardiomyopathy (243 views)
European Heart Journal (ISSN: 0195-668x), 1999 Sep; 20(ABSTR.SUPPL.): N/D-N/D.
Impact Factor: 3.21
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Colao A, Cuocolo A, Marzullo P, Nicolai E, Ferone D, Della Morte A, Petretta M, Salvatore M, Lombardi G
Impact of patient's age and disease duration on cardiac performance in acromegaly: A radionuclide angiography study (287 views)
J Clin Endocrinol Metab (ISSN: 0021-972x), 1999 May; 84(5): 1518-1523.
Impact Factor: 5.805
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Colao A, Lastoria S, Ferone D, Varrella P, Marzullo P, Pivonello R, Cerbone G, Acampa W, Salvatore M, Lombardi G
The pituitary uptake of In-111-DTPA-D-Phe(1)-octreotide in the normal pituitary and in pituitary adenomas (387 views)
J Endocrinol Invest (ISSN: 0391-4097, 1720-8386electronic), 1999 Mar; 22(3): 176-183.
Impact Factor: 0.957
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Colao A, Cuocolo A, Marzullo P, Nicolai E, Ferone D, Florimonte L, Salvatore M, Lombardi G
Effects of 1-year treatment with octreotide on cardiac performance in patients with acromegaly (364 views)
J Clin Endocrinol Metab (ISSN: 0021-972x), 1999 Jan; 84(1): 17-23.
Impact Factor: 5.805
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Lastoria S, Vergara E, Palmieri G, Acampa W, Varrella P, Caracò C, Bianco RA, Muto P, Salvatore M
In vivo detection of malignant thymic masses by indium-111-DTPA-D- Phe1-octreotide scintigraphy (428 views)
J Nucl Med (ISSN: 0161-5505, 1535-5667, 1535-5667electronic), 1998 Apr; 39(4): 634-639.
Impact Factor: 3.064
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Longobardi S, Cuocolo A, Merola B, Di Rella F, Colao A, Nicolai E, Cardei S, Salvatore M, Lombardi G
Left ventricular function in young adults with childhood and adulthood onset growth hormone deficiency (434 views)
Clin Endocrinol (ISSN: 0300-0664, 1365-2265, 1365-2265electronic), 1998 Feb; 48(2): 137-143.
Impact Factor: 3.101
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Ferone D, Lastoria S, Colao A, Varrella P, Cerbone G, Acampa W, Merola B, Salvatore M, Lombardi G
Correlation of scintigraphic results using 123I-methoxybenzamide with hormone levels and tumor size response to quinagolide in patients with pituitary adenomas (316 views)
J Clin Endocrinol Metab (ISSN: 0021-972x), 1998 Jan; 83(1): 248-252.
Impact Factor: 5.641
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Lombardi G, Colao A, Cuocolo A, Longobardi S, Di Somma C, Orio F, Merola B, Nicolai E, Salvatore M
Cardiological aspects of growth hormone and insulin-like growth factor- (437 views)
J Pediatr Endocrinol Metab (ISSN: 0334-018x), 1997 Nov; 10(6): 553-560.
Impact Factor: 0.481
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Maurea S, Lastoria S, Caracò C, Klain M, Varrella P, Acampa W, Muto P, Salvatore M
The role of radiolabeled somatostatin analogs in adrenal imaging (358 views)
Nucl Med Biol (ISSN: 0969-8051, 0883-2897), 1996 Sep; 23(6): 677-680.
Impact Factor: 1.042
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Lastoria S, Maurea S, Vergara E, Acampa W, Varrella P, Klain M, Muto P, Bernardy JD, Salvatore M
Comparison of labeled MIBG and somatostatin analogs in imaging neuroendocrine tumors (336 views)
Q J Nucl Med (ISSN: 1125-0135, 1124-3937), 1995 Dec; 39(4Suppl1): 145-149.
Impact Factor: 2.125
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Cuocolo A, Nicolai E, Fazio S, Pace L, Maurea S, Cittadini A, Sacca L, Salvatore M
Impaired left ventricular diastolic filling in patients with acromegaly: Assessment with radionuclide angiography (261 views)
J Nucl Med (ISSN: 0161-5505, 1535-5667, 1535-5667electronic), 1995 Feb; 36(2): 196-201.
Impact Factor: 3.491
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Palmeieri G, Lastoria S, Vergara E, Varrella P, Acampa W, Salvatore M, Bianco AR
Diagnosis and treatment of thymoma by octreotide (234 views)
Meetingproceedings Of The American Association For Cancer Research Annual (ISSN: 0197-016x), 1995; 36(0): N/D-N/D.
Impact Factor: 0
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LASTORIA S, COLAO A, VERGARA E, FERONE D, VARRELLA P, MEROLA B, ACAMPA W, LOMBARDI G, SALVATORE M
IN-111 OCTREOTIDE UPTAKE LEVELS IN PITUITARY-ADENOMAS TO PREDICT THE RESPONSIVENESS TO CHRONIC OCTREOTIDE TREATMENT (240 views)
J Nucl Med (ISSN: 0161-5505, 1535-5667, 1535-5667electronic), 1994 May; 35(5): N/D-N/D.
Impact Factor: 3.491
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LASTORIA S, VERGARA E, VARRELLA P, ACAMPA W, PALMIERI G, SALVATORE M
IN-VIVO DETECTION OF NEW DISEASES EXPRESSING SOMATOSTATIN RECEPTORS BY IN-111 OCTREOTIDE (267 views)
J Nucl Med (ISSN: 0161-5505, 1535-5667, 1535-5667electronic), 1994 May; 35(5): N/D-N/D.
Impact Factor: 3.491
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LASTORIA S, VERGARA E, VARRELLA P, ACAMPA W, PALMIERI G, SALVATORE M
IN-VIVO DETECTION OF NEW NEOPLASTIC LESIONS EXPRESSING SOMATOSTATIN RECEPTORS USING IN-111 OCTREOTIDE (293 views)
Posters Tomes 1 4proceedings Of The Xvi International Cancer Congress Free Papers And, 1994; N/D: N/D-N/D.
Impact Factor: 0
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Nappi A, Cuocolo A, Nicolai E, Imbriaco M, Pace L, Salvatore M
Ambulatory monitoring of left ventricular function with a radionuclide detector system (295 views)
Radiol Med (ISSN: 0033-8362, 1826-6983, 1826-6983electronic), 1992; 84(1-2): 132-139.
Impact Factor: 0.967
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Pezzino V, Papa V, Trischitta V, Brunetti A, Goodman PA, Treutelaar MK, Williams JA, Maddux BA, Vigneri R, Goldfine ID
Human insulin receptor radioimmunoassay: Applicability to insulin-resistant states (263 views)
Am J Physiol Endocrinol Metab (ISSN: 0002-9513), 1989 Sep; 257(3): N/D-N/D.
Impact Factor: 3.116
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79 Records (64 excluding Abstracts).
Total impact factor: 316.586 (259.463 excluding Abstracts).
Total 5 year impact factor: 286.666 (226.767 excluding Abstracts).
Total impact factor: 316.586 (259.463 excluding Abstracts).
Total 5 year impact factor: 286.666 (226.767 excluding Abstracts).
314 views. Last view on Monday 06 March 2023, 0:06:02
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