One-year effect of myocardial revascularization on resting left ventricular function and regional thallium uptake in chronic CAD(364 views) Cuocolo A, Nicolai E, Petretta M, Morisco C, DeLuca N, Salvatore M, Trimarco B
Affiliations: Nucl. Med. Ctr. Natl. Cncl. of Res., University Federico II, via Pansini 5-80131, Naples, Italy
References: Ross Jr., J., Myocardial perfusion-contraction matching: Implications for coronary artery disease and hibernation (1991) Circulation, 83, pp. 1076-108
Dilsizian, V., Bonow, R.O., Current diagnostic techniques of assessing myocardial viability in hibernating and stunned myocardium (1993) Circulation, 87, pp. 1-20
Bonow, R.O., The hibernating myocardium: Implication for management of congestive heart failure (1995) Am J Cardiol, 75, pp. 17A-25A
Ragosta, M., Beller, G.A., Watson, D.D., Kaul, S., Gimple, L.W., Quantitative planar rest-redistribution thallium-201 imaging in detection of myocardial viability and prediction of improvement in left ventricular function after coronary bypass surgery in patients with severely depressed left ventricular function (1993) Circulation, 87, pp. 1630-1641
Vom Dahl, J., Eitzman, D.T., Al-Aouar, Z.R., Relation of regional function, perfusion and metabolism in patients with advanced coronary artery disease undergoing surgical revascularization (1994) Circulation, 90, pp. 2356-2366
Tamaki, N., Kawamoto, M., Tadamura, E., Prediction of reversible ischemia after revascularization: Perfusion and metabolic studies with PET (1995) Circulation, 91, pp. 1697-1705
Newhouse, H.K., Wexler, J.P., Myocardial perfusion imaging for evaluating intervention in coronary artery disease (1995) Semin Nucl Med, 25, pp. 15-27
Perrone-Filardi, P., Pace, L., Prastaro, M., Assessment of myocardial viability in patients with chronic coronary artery disease: Rest 4-hour-24-hour thallium-201 tomography versus dobutamine echocardiography (1996) Circulation, 94, pp. 2712-2719
Qureshi, U., Nagueh, S.F., Afridi, I., Dobutamine echocardiography and quantitative rest-redistribution thallium-201 tomography in myocardial hibernation: Relation of contractile reserve to thallium-201 uptake and comparative prediction of recovery of function (1997) Circulation, 95, pp. 626-635
Galli, M., Marcassa, C., Bolli, R., Spontaneous delayed recovery of perfusion and contraction the first 5 weeks after anterior infarction: Evidence for the presence of hibernating myocardium in the infarcted area (1994) Circulation, 90, pp. 1386-1397
Maurea, S., Cuocolo, A., Soricelli, A., Enhanced detection of viable myocardium by technetium-99m methoxyisobutyl isonitrile tomography after nitrates administration in patients with chronic coronary artery disease (1995) J Nucl Med, 36, pp. 1945-1952
Cuocolo, A., Nicolai, E., Soricelli, A., Technetium-99m tetrofosmin myocardial tomography in patients with coronary artery disease: Comparison between adenosine and dynamic exercise stress testing (1996) J Nucl Cardiol, 3, pp. 194-203
Bonow, R.O., Dilsizian, V., Cuocolo, A., Bacharach, S.L., Identification of viable myocardium in patients with chronic coronary artery disease and left ventricular dysfunction: Comparison of thallium scintigraphy with reinjection and PET imaging with fluorine-18-fluorodeoxyglucose (1991) Circulation, 83, pp. 26-37
Volpe, M., Rao, M.A.E., Cuocolo, A., Radionuclide monitoring of cardiac adaptations to volume loading in patients with dilated cardiomyopathy and mild heart failure (1995) Circulation, 92, pp. 2511-2518
Shiller, N.B., Shah, P.M., Crawford, M., American Society of Echocardiography Committee on Standards, Subcommittee on Quantitation of Two-Dimensional Echocardiograms: Recommendations for quantitation of the left ventricle by two-dimensional echocardiography (1989) J Am Soc Echocardiol, 2, pp. 358-367
La Canna, G., Alfieri, O., Giubbini, R., Gargano, M., Ferrari, R., Visioli, O., Echocardiography during infusion of dobutamine for identification of reversible dysfunction in patients with chronic coronary artery disease (1994) J Am Coll Cardiol, 23, pp. 617-626
Bisi, G., Sciagrà, R., Santoro, G.M., Fazzini, P.F., Rest lechnetium-99m-sestamibi tomography in combination with short-term administration of nitrates: Feasibility and reliability for prediction of postrevascularization outcome of asynergic territories (1994) J Am Coll Cardiol, 24, pp. 1282-1289
Dilsizian, V., Rocco, T.P., Freedman, N.M.T., Leon, M.B., Bonow, R.O., Enhanced detection of ischemic but viable myocardium by the reinjection of thallium after stress-redistribution imaging (1990) N Engl J Med, 323, pp. 141-146
Tamaki, N., Ohtani, H., Yonekura, Y., Significance of fill-in after thallium-201 reinjection following delayed imaging: Comparison with regional wall motion and angiographic findings (1990) J Nucl Med, 31, pp. 1617-1623
Ritchie, J.L., Albro, D.C., Caldwell, J.H., Trobaugh, G.B., Hamilton, G.W., Thallium-201 myocardial imaging: A comparison of the redistribution and rest images (1979) J Nucl Med, 20, pp. 477-483
Mori, T., Minamiji, K., Kurogane, H., Ogawa, K., Yoshida, Y., Rest-injected thallium-201 imaging for assessing viability of severe asynergic regions (1991) J Nucl Med, 32, pp. 1718-1724
Gewirtz, H., Beller, G.A., Strauss, H.W., Transient defects of resting thallium scans in patients with coronary artery disease (1979) Circulation, 59, pp. 707-713
Berger, B.C., Watson, D.D., Burwell, L.R., Redistribution of thallium at rest in patients with stable and unstable angina and the effects of coronary artery bypass surgery (1979) Circulation, 60, pp. 1114-1125
Petretta, M., Cuocolo, A., Bonaduce, D., Incremental prognostic value of thallium reinjection after stress-redistribution imaging in patients with previous myocardial infarction and left ventricular dysfunction (1997) J Nucl Med, 38, pp. 195-200
Strauss, W., Harrison, K., Langen, J.K., Lebowitz, E., Put, B., Thallium-201 for myocardial imaging: Relation of thallium-201 to regional myocardial perfusion (1975) Circulation, 51, pp. 641-650
Grunwald, A.M., Watson, D.D., Holizgrafe, H.H., Irving, J.F., Beller, G.A., Myocardial thallium-201 kinetics in normal and ischemic myocardium (1981) Circulation, 64, pp. 610-619
Beller, G.A., Holizgrafe, H.H., Watson, D.D., Intrinsic washout rate of thallium-201 in normal and ischemie myocardium after dipyridamole-induced vasodilatation (1985) Circulation, 71, pp. 378-388
Di Carli, M.F., Asgarzadie, F., Schelbert, H.R., Quantitative relation between myocardial viability and improvement in heart failure symptoms after revascularization in patients with ischemic cardiomyopathy (1995) Circulation, 92, pp. 3436-3444
Ito, H., Tomooka, T., Sakai, N., Time course of functional improvement in stunned myocardium in risk area in patients with reperfused anterior infarction (1993) Circulation, 87, pp. 355-362
Picard, H.M., Wilkins, G.T., Ray, P., Weyman, A.E., Long-term effects of acute thrombolytic therapy on ventricular size and function (1993) Am Heart J, 126, pp. 1-10
Bolli, R., Myocardial stunning in men (1992) Circulation, 86, pp. 1671-1691
Christian, T.F., Behrenbeck, T., Pellikka, P.A., Huber, K.C., Chesebro, J.H., Gibbons, R.J., Mismatch of left ventricular function and infarct size demonstrated by technetium-99m isonitrile imaging after reperfusion therapy for acute myocardial infarction: Identification of myocardial stunning and hyperkinesia (1990) J Am Coll Cardiol, 16, pp. 1632-1638
Bonow, R. O., The hibernating myocardium: Implication for management of congestive heart failure (1995) Am J Cardiol, 75, pp. 17A-25A
Newhouse, H. K., Wexler, J. P., Myocardial perfusion imaging for evaluating intervention in coronary artery disease (1995) Semin Nucl Med, 25, pp. 15-27
Bonow, R. O., Dilsizian, V., Cuocolo, A., Bacharach, S. L., Identification of viable myocardium in patients with chronic coronary artery disease and left ventricular dysfunction: Comparison of thallium scintigraphy with reinjection and PET imaging with fluorine-18-fluorodeoxyglucose (1991) Circulation, 83, pp. 26-37
Volpe, M., Rao, M. A. E., Cuocolo, A., Radionuclide monitoring of cardiac adaptations to volume loading in patients with dilated cardiomyopathy and mild heart failure (1995) Circulation, 92, pp. 2511-2518
Shiller, N. B., Shah, P. M., Crawford, M., American Society of Echocardiography Committee on Standards, Subcommittee on Quantitation of Two-Dimensional Echocardiograms: Recommendations for quantitation of the left ventricle by two-dimensional echocardiography (1989) J Am Soc Echocardiol, 2, pp. 358-367
Bisi, G., Sciagr, R., Santoro, G. M., Fazzini, P. F., Rest lechnetium-99m-sestamibi tomography in combination with short-term administration of nitrates: Feasibility and reliability for prediction of postrevascularization outcome of asynergic territories (1994) J Am Coll Cardiol, 24, pp. 1282-1289
Ritchie, J. L., Albro, D. C., Caldwell, J. H., Trobaugh, G. B., Hamilton, G. W., Thallium-201 myocardial imaging: A comparison of the redistribution and rest images (1979) J Nucl Med, 20, pp. 477-483
Berger, B. C., Watson, D. D., Burwell, L. R., Redistribution of thallium at rest in patients with stable and unstable angina and the effects of coronary artery bypass surgery (1979) Circulation, 60, pp. 1114-1125
Pohost, G. M., Aipert, N. M., Ingwall, J. S., Strauss, W. H., Thallium-201 redistribution: Mechanism and clinical utility (1980) Semin Nucl Med, 10, pp. 70-93
Grunwald, A. M., Watson, D. D., Holizgrafe, H. H., Irving, J. F., Beller, G. A., Myocardial thallium-201 kinetics in normal and ischemic myocardium (1981) Circulation, 64, pp. 610-619
Beller, G. A., Holizgrafe, H. H., Watson, D. D., Intrinsic washout rate of thallium-201 in normal and ischemie myocardium after dipyridamole-induced vasodilatation (1985) Circulation, 71, pp. 378-388
Di Carli, M. F., Asgarzadie, F., Schelbert, H. R., Quantitative relation between myocardial viability and improvement in heart failure symptoms after revascularization in patients with ischemic cardiomyopathy (1995) Circulation, 92, pp. 3436-3444
Picard, H. M., Wilkins, G. T., Ray, P., Weyman, A. E., Long-term effects of acute thrombolytic therapy on ventricular size and function (1993) Am Heart J, 126, pp. 1-10
Christian, T. F., Behrenbeck, T., Pellikka, P. A., Huber, K. C., Chesebro, J. H., Gibbons, R. J., Mismatch of left ventricular function and infarct size demonstrated by technetium-99m isonitrile imaging after reperfusion therapy for acute myocardial infarction: Identification of myocardial stunning and hyperkinesia (1990) J Am Coll Cardiol, 16, pp. 1632-1638
One-year effect of myocardial revascularization on resting left ventricular function and regional thallium uptake in chronic CAD
It is still unclear whether in patients with chronic coronary artery disease (CAD) the improvements in myocardial perfusion and left ventricular (LV) function induced by revascularization persist in the long run. This study was planned to evaluate the 1-yr effects of successful revascularization on myocardial perfusion and LV function in patients with CAD and to assess the accuracy of thallium imaging in the prediction of functional recovery 1 yr after revascularization. Methods: Thirty-eight patients with chronic CAD who were revascularized (experimental group) underwent, while off drugs, 201TI tomography, two-dimensional echocardiography and radionuclide angiography before and after a 1-yr follow- up. Twenty-nine patients with similar characteristics who were not revascularized (control group) and completed the 1-yr follow-up were also studied. Regional thallium activity was quantitatively measured in 13 segments per patient. Systolic function was assessed by echocardiography in corresponding segments. Results: In the experimental group, at baseline, on the basis of regional LV function and thallium uptake, 276 segments were normal, 169 dysfunctional-viable and 49 nonviable. After revascularization, the majority (75%) of the dysfunctional-viable segments at baseline showed functional recovery at follow-up, whereas the majority (81%) of the nonviable segments at baseline did not. Simultaneously, LV ejection fraction increased 4 wk after revascularization (from 39% ± 9% to 42% ± 10%, p < 0.01) and remained unchanged after 1-yr (43% ± 8%, p < 0.01 versus baseline study). LV wall-motion score index after 1 yr was reduced (from 1.68 ± 0.4 to 1.42 ± 0.3, p < 0.001) as compared with baseline. On the contrary, in the control group, no change in myocardial perfusion and LV function was detected after the 1-yr follow-up. Conclusion: In patients with chronic CAD, successful coronary revascularization induces a stable improvement in myocardial perfusion and LV function, which is still detectable after a 1-yr follow-up. Furthermore, preserved thallium uptake in dysfunctional regions is predictive of functional recovery after revascularization.
One-year effect of myocardial revascularization on resting left ventricular function and regional thallium uptake in chronic CAD
Hesse B, Tagil K, Cuocolo A, Anagnostopoulos C, Bardies M, Bax J, Bengel F, Busemann Sokole E, Davies G, Dondi M, Edenbrandt L, Franken P, Kjaer A, Knuuti J, Lassmann M, Ljungberg M, Marcassa C, Marie PY, Mckiddie F, O'connor M, Prvuolovich E, Underwood R * 3. 0 T perfusion MR imaging(694 views) Rivista Di Neuroradiologia (ISSN: 1120-9976), 2004; 17(6): 807-812. Impact Factor:0.023 ViewExport to BibTeXExport to EndNote