Impaired cardiac reserve and exercise capacity in patients receiving long-term thyrotropin suppressive therapy with levothyroxine (336 views)
J Clin Endocrinol Metab (ISSN: 0021-972x), 1996 Dec; 81(12): 4224-4228.
Export to BibTeX Export to EndNote
Paper type: Journal Article,
Impact factor: 4.575, 5-year impact factor: 6.004
Url: http://www.scopus.com/inward/record.url?eid=2-s2.0-0029802333&partnerID=40&md5=04d0d502247a0ed2458edb7b67e55668
Keywords: Beta Adrenergic Receptor Blocking Agent, Bisoprolol, Levothyroxine, Liothyronine, Thyrotropin, Adult, Article, Bicycle Ergometry, Clinical Article, Clinical Trial, Controlled Clinical Trial, Controlled Study, Exercise Tolerance, Female, Goiter, Heart Left Ventricle Function, Human, Long Term Care, Priority Journal, Scintiangiography, Thyroid Carcinoma, Thyroid Disease, Adrenergic Beta-Antagonists, Middle Aged, Ventricular Function,
Affiliations:
Depts. Int. Med., Endocrinol., N., Univ. Federico II Medical School, Naples, Italy
Medicina Interna, Via Pansini 5, 80131 Naples, Italy
References:
Mandel, S.J., Brent, G.A., Larsen, P.R., Levothyroxine therapy in patients with thyroid disease (1993) Ann Intern Med, 119, pp. 492-50
Hennessey, J.V., Evaul, J.E., Tseng, Y.C., Burman, K.D., Wartofsky, L., L-Thyroxine dosage: A reevaluation of therapy with contemporary preparations (1986) Ann Intern Med, 105, pp. 11-15
Ross, D.S., Daniels, G.H., Gouveia, D., The use and limitations of a chemiluminescent thyrotropin assay as a single thyroid function test in an out-patient endocrine clinic (1990) J Clin Endocrinol Metab, 71, pp. 764-769
Ross, D.S., Neer, R.M., Ridgway, E.C., Daniels, G.H., Subclinical hyperthyroidism and reduced bone density as a possible result of prolonged suppression of the pituitary-thyroid axis with l-thyroxine (1987) Am J Med, 82, pp. 1167-1170
Paul, T.L., Kerrigan, J., Kelly, A.M., Braverman, L.E., Baran, D.T., Long-term l-thyroxine therapy is associated with decreased hip bone density in premenopausal women (1988) JAMA, 259, pp. 3137-3141
Faber, J., Galloe, A.M., Changes in bone mass during prolonged subclinical hyperthyroidism due to l-thyroxine treatment: A meta-analysis (1994) Eur J Endocrinol, 130, pp. 350-356
Biondi, B., Fazio, S., Carella, C., Cardiac effects of long term thyrotropin-suppressive therapy with levothyroxine (1993) J Clin Endocrinol Metab, 77, pp. 334-338
Fazio, S., Biondi, B., Carella, C., Diastolic dysfunction in patients on thyrotropin-suppressive therapy with levothyroxine: Beneficial effect of β-blockade (1995) J Clin Endocrinol Metab, 80, pp. 2222-2226
Bonow, R.O., Udelson, J.E., Left ventricular diastolic dysfunction as a cause of congestive heart failure (1992) Ann Intern Med, 117, pp. 502-510
Klein, I., Trzepacz, P., Roberts, M., Levey, G.S., Symptom rating scale for assessing hyperthyroidism (1988) Arch Intern Med, 148, pp. 387-390
Kannel, W.B., Sorlie, P., Some health benefits of physical activity. The Framingham study (1979) Arch Intern Med, 139, pp. 857-861
Cuocolo, A., Sax, F.L., Brush, J.E., Maron, B.J., Bacharach, S.L., Bonow, R.O., Left ventricular hypertrophy and impaired diastolic filling in essential hypertension. Diastolic mechanisms for systolic dysfunction during exercise (1990) Circulation, 81, pp. 978-986
Cuocolo, A., Nicolai, E., Fazio, S., Impaired left ventricular diastolic filling in patients with acromegaly: Assessment with radionuclide angiography (1995) J Nucl Med, 36, pp. 196-201
Utiger, R.D., Subclinical hyperthyroidism - Just a low serum thyrotropin concentration or something more? (1994) N Engl J Med, 331, pp. 1302-1303
Sawin, C.T., Geller, A., Wolf, P.A., Low serum thyrotropin concentrations as a risk factor for atrial fibrillation in older persons (1994) N Engl J Med, 331, pp. 1249-1252
Sandler, G., Wilson, G.M., The nature and prognosis of heart disease in thyrotoxicosis: A review of 150 patients treated with 131I (1959) Q J Med, 28, pp. 347-369
Minz, G., Pizzarello, R., Klein, I., Enhanced left ventricular diastolic function in hyperthyroidism: Noninvasive assessment and response to treatment (1991) J Clin Endocrinol Metab, 73, pp. 146-150
Merillon, J.P., Passa, P.H., Chastre, J., Gourgon, R., Left ventricular function and hyperthyroidism (1981) Br Heart J, 46, pp. 137-143
Suko, J., The calcium pump of calcium sarcoplasmic reticulum: Functional alterations at different levels of thyroid state in rabbits (1973) J Physiol, 228, pp. 563-582
Rohrer, D., Dilmann, W.H., Thyroid hormones markedly increase the mRNA coding for sarcoplasmic reticulum Ca2+-ATPase in the rat heart (1988) J Biol Chem, 263, pp. 6941-6944
Amidi, M., Leon, D.F., DeGroot, W.J., Kroetz, F.W., Leonard, J.J., Effect of the thyroid state on myocardial contractility and ventricular ejection rate in man (1968) Circulation, 38, pp. 229-239
Grossman, W., Robin, N.I., Johnson, L.W., Brooks, H.L., Selenkow, H.A., Dexter, L., The enhanced myocardial contractility of thyrotoxicosis. Role of the beta adrenergic receptor (1971) Ann Intern Med, 74, pp. 869-874
Parisi, A.F., Hamilton, B.P., Thomas, C.N., Mazzaferri, E.L., The short cardiac pre-ejection period: An index to thyrotoxicosis (1974) Circulation, 49, pp. 900-904
Cohen, M.V., Schulman, I.C., Spenillo, A., Surks, M.I., Effects of thyroid hormone on left ventricular function in patients treated for thyrotoxicosis (1981) Am J Cardiol, 48, pp. 33-38
Shafer, R.B., Bianco, J.A., Assessment of cardiac reserve in patients with hyperthyroidism (1980) Chest, 78, pp. 269-273
Forfar, J.C., Muir, A.L., Sawers, S.A., Toft, A.D., Abnormal left ventricular function in hyperthyroidism (1982) N Engl J Med, 307, pp. 1165-1170
Feldman, T., Borow, K.M., Same, D.H., Neumann, A., Lang, R.M., Myocardial mechanics in hyperthyroidism: Importance of left ventricular loading conditions, heart rate and contractile state (1986) J Am Coll Cardiol, 7, pp. 967-974
Iskandrian, A.S., Rose, L., Hakki, A.-H., Segal, B.L., Kane, S.A., Cardiac performance in thyrotoxicosis: Analysis of 10 untreated patients (1983) Am J Cardiol, 51, pp. 349-352
Bevilacqua, M., Savonitto, S., Bosisio, E., Role of the Frank-Starling mechanism in maintaining cardiac output during increasing levels of treadmill exercise in beta-blocked normal men (1989) Am J Cardiol, 63, pp. 853-857
Clifton, G.D., Harrison, M.R., DeMaria, A.N., Influence of beta-adrenergic blockade upon hemodynamic response to exercise assessed by Doppler echocardiography (1990) Am Heart J, 120, pp. 579-585
Martin III, W.H., Spina, R.J., Korte, E., Mechanisms of impaired exercise capacity in short duration experimental hyperthyroidism (1991) J Clin Invest, 88, pp. 2047-2053
Olson, B.R., Klein, I., Benner, R., Burdett, R., Trzepacz, P., Levey, G.S., Hyperthyroid myopathy and response to treatment (1991) Thyroid, 1, pp. 137-141
Twentyman, O.P., Disley, A., Gribbin, H.R., Alberti, K.G., Tattersfield, A.E., Effect of beta-adrenergic blockade on respiratory and metabolic responses to exercise (1931) J Appl Physiol, 51, pp. 788-793
Lundborg, P., Åström, H., Bengtsson, C., Effect of beta-adrenoceptor blockade on exercise performance and metabolism (1981) Clin Sci, 61, pp. 299-305
Smith, R.S., Warren, D.J., Effect of acute oral beta-adrenergic blockade on muscle blood flow in man (1982) Cardiovasc Res, 16, pp. 205-208
Challiss, R.A.J., Hayes, D.J., Radda, G.K., A 31P-n.m.r. study of the acute effects of β-blockade on the bioenergetics of skeletal muscle during contractien (1987) Biochem J, 246, pp. 163-172
Mandel, S. J., Brent, G. A., Larsen, P. R., Levothyroxine therapy in patients with thyroid disease (1993) Ann Intern Med, 119, pp. 492-50
Hennessey, J. V., Evaul, J. E., Tseng, Y. C., Burman, K. D., Wartofsky, L., L-Thyroxine dosage: A reevaluation of therapy with contemporary preparations (1986) Ann Intern Med, 105, pp. 11-15
Ross, D. S., Daniels, G. H., Gouveia, D., The use and limitations of a chemiluminescent thyrotropin assay as a single thyroid function test in an out-patient endocrine clinic (1990) J Clin Endocrinol Metab, 71, pp. 764-769
Ross, D. S., Neer, R. M., Ridgway, E. C., Daniels, G. H., Subclinical hyperthyroidism and reduced bone density as a possible result of prolonged suppression of the pituitary-thyroid axis with l-thyroxine (1987) Am J Med, 82, pp. 1167-1170
Paul, T. L., Kerrigan, J., Kelly, A. M., Braverman, L. E., Baran, D. T., Long-term l-thyroxine therapy is associated with decreased hip bone density in premenopausal women (1988) JAMA, 259, pp. 3137-3141
Bonow, R. O., Udelson, J. E., Left ventricular diastolic dysfunction as a cause of congestive heart failure (1992) Ann Intern Med, 117, pp. 502-510
Kannel, W. B., Sorlie, P., Some health benefits of physical activity. The Framingham study (1979) Arch Intern Med, 139, pp. 857-861
Utiger, R. D., Subclinical hyperthyroidism - Just a low serum thyrotropin concentration or something more? (1994) N Engl J Med, 331, pp. 1302-1303
Sawin, C. T., Geller, A., Wolf, P. A., Low serum thyrotropin concentrations as a risk factor for atrial fibrillation in older persons (1994) N Engl J Med, 331, pp. 1249-1252
Merillon, J. P., Passa, P. H., Chastre, J., Gourgon, R., Left ventricular function and hyperthyroidism (1981) Br Heart J, 46, pp. 137-143
Parisi, A. F., Hamilton, B. P., Thomas, C. N., Mazzaferri, E. L., The short cardiac pre-ejection period: An index to thyrotoxicosis (1974) Circulation, 49, pp. 900-904
Cohen, M. V., Schulman, I. C., Spenillo, A., Surks, M. I., Effects of thyroid hormone on left ventricular function in patients treated for thyrotoxicosis (1981) Am J Cardiol, 48, pp. 33-38
Shafer, R. B., Bianco, J. A., Assessment of cardiac reserve in patients with hyperthyroidism (1980) Chest, 78, pp. 269-273
Forfar, J. C., Muir, A. L., Sawers, S. A., Toft, A. D., Abnormal left ventricular function in hyperthyroidism (1982) N Engl J Med, 307, pp. 1165-1170
Iskandrian, A. S., Rose, L., Hakki, A. -H., Segal, B. L., Kane, S. A., Cardiac performance in thyrotoxicosis: Analysis of 10 untreated patients (1983) Am J Cardiol, 51, pp. 349-352
Clifton, G. D., Harrison, M. R., DeMaria, A. N., Influence of beta-adrenergic blockade upon hemodynamic response to exercise assessed by Doppler echocardiography (1990) Am Heart J, 120, pp. 579-585
Martin III, W. H., Spina, R. J., Korte, E., Mechanisms of impaired exercise capacity in short duration experimental hyperthyroidism (1991) J Clin Invest, 88, pp. 2047-2053
Olson, B. R., Klein, I., Benner, R., Burdett, R., Trzepacz, P., Levey, G. S., Hyperthyroid myopathy and response to treatment (1991) Thyroid, 1, pp. 137-141
Twentyman, O. P., Disley, A., Gribbin, H. R., Alberti, K. G., Tattersfield, A. E., Effect of beta-adrenergic blockade on respiratory and metabolic responses to exercise (1931) J Appl Physiol, 51, pp. 788-793
Lundborg, P., str m, H., Bengtsson, C., Effect of beta-adrenoceptor blockade on exercise performance and metabolism (1981) Clin Sci, 61, pp. 299-305
Smith, R. S., Warren, D. J., Effect of acute oral beta-adrenergic blockade on muscle blood flow in man (1982) Cardiovasc Res, 16, pp. 205-208
Challiss, R. A. J., Hayes, D. J., Radda, G. K., A 31P-n. m. r. study of the acute effects of -blockade on the bioenergetics of skeletal muscle during contractien (1987) Biochem J, 246, pp. 163-172
J Clin Endocrinol Metab (ISSN: 0021-972x), 1996 Dec; 81(12): 4224-4228.
Export to BibTeX Export to EndNote
Paper type: Journal Article,
Impact factor: 4.575, 5-year impact factor: 6.004
Url: http://www.scopus.com/inward/record.url?eid=2-s2.0-0029802333&partnerID=40&md5=04d0d502247a0ed2458edb7b67e55668
Keywords: Beta Adrenergic Receptor Blocking Agent, Bisoprolol, Levothyroxine, Liothyronine, Thyrotropin, Adult, Article, Bicycle Ergometry, Clinical Article, Clinical Trial, Controlled Clinical Trial, Controlled Study, Exercise Tolerance, Female, Goiter, Heart Left Ventricle Function, Human, Long Term Care, Priority Journal, Scintiangiography, Thyroid Carcinoma, Thyroid Disease, Adrenergic Beta-Antagonists, Middle Aged, Ventricular Function,
Affiliations:
Depts. Int. Med., Endocrinol., N., Univ. Federico II Medical School, Naples, Italy
Medicina Interna, Via Pansini 5, 80131 Naples, Italy
References:
Mandel, S.J., Brent, G.A., Larsen, P.R., Levothyroxine therapy in patients with thyroid disease (1993) Ann Intern Med, 119, pp. 492-50
Hennessey, J.V., Evaul, J.E., Tseng, Y.C., Burman, K.D., Wartofsky, L., L-Thyroxine dosage: A reevaluation of therapy with contemporary preparations (1986) Ann Intern Med, 105, pp. 11-15
Ross, D.S., Daniels, G.H., Gouveia, D., The use and limitations of a chemiluminescent thyrotropin assay as a single thyroid function test in an out-patient endocrine clinic (1990) J Clin Endocrinol Metab, 71, pp. 764-769
Ross, D.S., Neer, R.M., Ridgway, E.C., Daniels, G.H., Subclinical hyperthyroidism and reduced bone density as a possible result of prolonged suppression of the pituitary-thyroid axis with l-thyroxine (1987) Am J Med, 82, pp. 1167-1170
Paul, T.L., Kerrigan, J., Kelly, A.M., Braverman, L.E., Baran, D.T., Long-term l-thyroxine therapy is associated with decreased hip bone density in premenopausal women (1988) JAMA, 259, pp. 3137-3141
Faber, J., Galloe, A.M., Changes in bone mass during prolonged subclinical hyperthyroidism due to l-thyroxine treatment: A meta-analysis (1994) Eur J Endocrinol, 130, pp. 350-356
Biondi, B., Fazio, S., Carella, C., Cardiac effects of long term thyrotropin-suppressive therapy with levothyroxine (1993) J Clin Endocrinol Metab, 77, pp. 334-338
Fazio, S., Biondi, B., Carella, C., Diastolic dysfunction in patients on thyrotropin-suppressive therapy with levothyroxine: Beneficial effect of β-blockade (1995) J Clin Endocrinol Metab, 80, pp. 2222-2226
Bonow, R.O., Udelson, J.E., Left ventricular diastolic dysfunction as a cause of congestive heart failure (1992) Ann Intern Med, 117, pp. 502-510
Klein, I., Trzepacz, P., Roberts, M., Levey, G.S., Symptom rating scale for assessing hyperthyroidism (1988) Arch Intern Med, 148, pp. 387-390
Kannel, W.B., Sorlie, P., Some health benefits of physical activity. The Framingham study (1979) Arch Intern Med, 139, pp. 857-861
Cuocolo, A., Sax, F.L., Brush, J.E., Maron, B.J., Bacharach, S.L., Bonow, R.O., Left ventricular hypertrophy and impaired diastolic filling in essential hypertension. Diastolic mechanisms for systolic dysfunction during exercise (1990) Circulation, 81, pp. 978-986
Cuocolo, A., Nicolai, E., Fazio, S., Impaired left ventricular diastolic filling in patients with acromegaly: Assessment with radionuclide angiography (1995) J Nucl Med, 36, pp. 196-201
Utiger, R.D., Subclinical hyperthyroidism - Just a low serum thyrotropin concentration or something more? (1994) N Engl J Med, 331, pp. 1302-1303
Sawin, C.T., Geller, A., Wolf, P.A., Low serum thyrotropin concentrations as a risk factor for atrial fibrillation in older persons (1994) N Engl J Med, 331, pp. 1249-1252
Sandler, G., Wilson, G.M., The nature and prognosis of heart disease in thyrotoxicosis: A review of 150 patients treated with 131I (1959) Q J Med, 28, pp. 347-369
Minz, G., Pizzarello, R., Klein, I., Enhanced left ventricular diastolic function in hyperthyroidism: Noninvasive assessment and response to treatment (1991) J Clin Endocrinol Metab, 73, pp. 146-150
Merillon, J.P., Passa, P.H., Chastre, J., Gourgon, R., Left ventricular function and hyperthyroidism (1981) Br Heart J, 46, pp. 137-143
Suko, J., The calcium pump of calcium sarcoplasmic reticulum: Functional alterations at different levels of thyroid state in rabbits (1973) J Physiol, 228, pp. 563-582
Rohrer, D., Dilmann, W.H., Thyroid hormones markedly increase the mRNA coding for sarcoplasmic reticulum Ca2+-ATPase in the rat heart (1988) J Biol Chem, 263, pp. 6941-6944
Amidi, M., Leon, D.F., DeGroot, W.J., Kroetz, F.W., Leonard, J.J., Effect of the thyroid state on myocardial contractility and ventricular ejection rate in man (1968) Circulation, 38, pp. 229-239
Grossman, W., Robin, N.I., Johnson, L.W., Brooks, H.L., Selenkow, H.A., Dexter, L., The enhanced myocardial contractility of thyrotoxicosis. Role of the beta adrenergic receptor (1971) Ann Intern Med, 74, pp. 869-874
Parisi, A.F., Hamilton, B.P., Thomas, C.N., Mazzaferri, E.L., The short cardiac pre-ejection period: An index to thyrotoxicosis (1974) Circulation, 49, pp. 900-904
Cohen, M.V., Schulman, I.C., Spenillo, A., Surks, M.I., Effects of thyroid hormone on left ventricular function in patients treated for thyrotoxicosis (1981) Am J Cardiol, 48, pp. 33-38
Shafer, R.B., Bianco, J.A., Assessment of cardiac reserve in patients with hyperthyroidism (1980) Chest, 78, pp. 269-273
Forfar, J.C., Muir, A.L., Sawers, S.A., Toft, A.D., Abnormal left ventricular function in hyperthyroidism (1982) N Engl J Med, 307, pp. 1165-1170
Feldman, T., Borow, K.M., Same, D.H., Neumann, A., Lang, R.M., Myocardial mechanics in hyperthyroidism: Importance of left ventricular loading conditions, heart rate and contractile state (1986) J Am Coll Cardiol, 7, pp. 967-974
Iskandrian, A.S., Rose, L., Hakki, A.-H., Segal, B.L., Kane, S.A., Cardiac performance in thyrotoxicosis: Analysis of 10 untreated patients (1983) Am J Cardiol, 51, pp. 349-352
Bevilacqua, M., Savonitto, S., Bosisio, E., Role of the Frank-Starling mechanism in maintaining cardiac output during increasing levels of treadmill exercise in beta-blocked normal men (1989) Am J Cardiol, 63, pp. 853-857
Clifton, G.D., Harrison, M.R., DeMaria, A.N., Influence of beta-adrenergic blockade upon hemodynamic response to exercise assessed by Doppler echocardiography (1990) Am Heart J, 120, pp. 579-585
Martin III, W.H., Spina, R.J., Korte, E., Mechanisms of impaired exercise capacity in short duration experimental hyperthyroidism (1991) J Clin Invest, 88, pp. 2047-2053
Olson, B.R., Klein, I., Benner, R., Burdett, R., Trzepacz, P., Levey, G.S., Hyperthyroid myopathy and response to treatment (1991) Thyroid, 1, pp. 137-141
Twentyman, O.P., Disley, A., Gribbin, H.R., Alberti, K.G., Tattersfield, A.E., Effect of beta-adrenergic blockade on respiratory and metabolic responses to exercise (1931) J Appl Physiol, 51, pp. 788-793
Lundborg, P., Åström, H., Bengtsson, C., Effect of beta-adrenoceptor blockade on exercise performance and metabolism (1981) Clin Sci, 61, pp. 299-305
Smith, R.S., Warren, D.J., Effect of acute oral beta-adrenergic blockade on muscle blood flow in man (1982) Cardiovasc Res, 16, pp. 205-208
Challiss, R.A.J., Hayes, D.J., Radda, G.K., A 31P-n.m.r. study of the acute effects of β-blockade on the bioenergetics of skeletal muscle during contractien (1987) Biochem J, 246, pp. 163-172
Mandel, S. J., Brent, G. A., Larsen, P. R., Levothyroxine therapy in patients with thyroid disease (1993) Ann Intern Med, 119, pp. 492-50
Hennessey, J. V., Evaul, J. E., Tseng, Y. C., Burman, K. D., Wartofsky, L., L-Thyroxine dosage: A reevaluation of therapy with contemporary preparations (1986) Ann Intern Med, 105, pp. 11-15
Ross, D. S., Daniels, G. H., Gouveia, D., The use and limitations of a chemiluminescent thyrotropin assay as a single thyroid function test in an out-patient endocrine clinic (1990) J Clin Endocrinol Metab, 71, pp. 764-769
Ross, D. S., Neer, R. M., Ridgway, E. C., Daniels, G. H., Subclinical hyperthyroidism and reduced bone density as a possible result of prolonged suppression of the pituitary-thyroid axis with l-thyroxine (1987) Am J Med, 82, pp. 1167-1170
Paul, T. L., Kerrigan, J., Kelly, A. M., Braverman, L. E., Baran, D. T., Long-term l-thyroxine therapy is associated with decreased hip bone density in premenopausal women (1988) JAMA, 259, pp. 3137-3141
Bonow, R. O., Udelson, J. E., Left ventricular diastolic dysfunction as a cause of congestive heart failure (1992) Ann Intern Med, 117, pp. 502-510
Kannel, W. B., Sorlie, P., Some health benefits of physical activity. The Framingham study (1979) Arch Intern Med, 139, pp. 857-861
Utiger, R. D., Subclinical hyperthyroidism - Just a low serum thyrotropin concentration or something more? (1994) N Engl J Med, 331, pp. 1302-1303
Sawin, C. T., Geller, A., Wolf, P. A., Low serum thyrotropin concentrations as a risk factor for atrial fibrillation in older persons (1994) N Engl J Med, 331, pp. 1249-1252
Merillon, J. P., Passa, P. H., Chastre, J., Gourgon, R., Left ventricular function and hyperthyroidism (1981) Br Heart J, 46, pp. 137-143
Parisi, A. F., Hamilton, B. P., Thomas, C. N., Mazzaferri, E. L., The short cardiac pre-ejection period: An index to thyrotoxicosis (1974) Circulation, 49, pp. 900-904
Cohen, M. V., Schulman, I. C., Spenillo, A., Surks, M. I., Effects of thyroid hormone on left ventricular function in patients treated for thyrotoxicosis (1981) Am J Cardiol, 48, pp. 33-38
Shafer, R. B., Bianco, J. A., Assessment of cardiac reserve in patients with hyperthyroidism (1980) Chest, 78, pp. 269-273
Forfar, J. C., Muir, A. L., Sawers, S. A., Toft, A. D., Abnormal left ventricular function in hyperthyroidism (1982) N Engl J Med, 307, pp. 1165-1170
Iskandrian, A. S., Rose, L., Hakki, A. -H., Segal, B. L., Kane, S. A., Cardiac performance in thyrotoxicosis: Analysis of 10 untreated patients (1983) Am J Cardiol, 51, pp. 349-352
Clifton, G. D., Harrison, M. R., DeMaria, A. N., Influence of beta-adrenergic blockade upon hemodynamic response to exercise assessed by Doppler echocardiography (1990) Am Heart J, 120, pp. 579-585
Martin III, W. H., Spina, R. J., Korte, E., Mechanisms of impaired exercise capacity in short duration experimental hyperthyroidism (1991) J Clin Invest, 88, pp. 2047-2053
Olson, B. R., Klein, I., Benner, R., Burdett, R., Trzepacz, P., Levey, G. S., Hyperthyroid myopathy and response to treatment (1991) Thyroid, 1, pp. 137-141
Twentyman, O. P., Disley, A., Gribbin, H. R., Alberti, K. G., Tattersfield, A. E., Effect of beta-adrenergic blockade on respiratory and metabolic responses to exercise (1931) J Appl Physiol, 51, pp. 788-793
Lundborg, P., str m, H., Bengtsson, C., Effect of beta-adrenoceptor blockade on exercise performance and metabolism (1981) Clin Sci, 61, pp. 299-305
Smith, R. S., Warren, D. J., Effect of acute oral beta-adrenergic blockade on muscle blood flow in man (1982) Cardiovasc Res, 16, pp. 205-208
Challiss, R. A. J., Hayes, D. J., Radda, G. K., A 31P-n. m. r. study of the acute effects of -blockade on the bioenergetics of skeletal muscle during contractien (1987) Biochem J, 246, pp. 163-172
Impaired cardiac reserve and exercise capacity in patients receiving long-term thyrotropin suppressive therapy with levothyroxine
To assess cardiac function and exercise tolerance in patients receiving long term TSH-suppressive therapy with levothyroxine (L-T4), we studied maximal exercise capacity with a bicycle ergometer and left ventricular function at rest and during physical exercise by radionuclide angiography. The evaluation was performed in 10 patients receiving L-T4 therapy (2.31 ± 0.13 μg/kg) for 5-9 yr, presenting with effort dyspnea and symptoms of adrenergic overactivity, and 10 matched control subjects. The patients were reassessed after 4 months of administration of the selective β-adrenergic blocker bisoprolol (4.25 ± 0.4 mg/day); L-T4 therapy remained unchanged. The results showed that at rest, left ventricular diastolic filling was impaired in the patients (P < 0.05), whereas systolic function was unaltered. During submaximal physical exercise, left ventricular ejection fraction increased in the controls from 58 ± 2% to 65 ± 2% (P < 0.001), whereas in the patients it fell from 63 ± 2% to 53 ± 2% (P < 0.01), mainly because of increased end-systolic left ventricular volume (P < 0.05). Exercise capacity was markedly reduced in the patients in terms of both peak workload (P < 0.001) and exercise duration (P < 0.001). β-Adrenergic blockade prevented both the fall in ejection fraction and the increase in end-systolic volume during exercise, and improved exercise tolerance. In conclusion, our data show that long term TSH-suppressive therapy with L-T4 is not as harmless as believed, because it may cause marked impairment of cardiac functional reserve and physical exercise capacity. Administration of a β-blocking drug for 4 months caused significant improvement of cardiac performance and exercise tolerance.
To assess cardiac function and exercise tolerance in patients receiving long term TSH-suppressive therapy with levothyroxine (L-T4), we studied maximal exercise capacity with a bicycle ergometer and left ventricular function at rest and during physical exercise by radionuclide angiography. The evaluation was performed in 10 patients receiving L-T4 therapy (2.31 ± 0.13 μg/kg) for 5-9 yr, presenting with effort dyspnea and symptoms of adrenergic overactivity, and 10 matched control subjects. The patients were reassessed after 4 months of administration of the selective β-adrenergic blocker bisoprolol (4.25 ± 0.4 mg/day); L-T4 therapy remained unchanged. The results showed that at rest, left ventricular diastolic filling was impaired in the patients (P < 0.05), whereas systolic function was unaltered. During submaximal physical exercise, left ventricular ejection fraction increased in the controls from 58 ± 2% to 65 ± 2% (P < 0.001), whereas in the patients it fell from 63 ± 2% to 53 ± 2% (P < 0.01), mainly because of increased end-systolic left ventricular volume (P < 0.05). Exercise capacity was markedly reduced in the patients in terms of both peak workload (P < 0.001) and exercise duration (P < 0.001). β-Adrenergic blockade prevented both the fall in ejection fraction and the increase in end-systolic volume during exercise, and improved exercise tolerance. In conclusion, our data show that long term TSH-suppressive therapy with L-T4 is not as harmless as believed, because it may cause marked impairment of cardiac functional reserve and physical exercise capacity. Administration of a β-blocking drug for 4 months caused significant improvement of cardiac performance and exercise tolerance.
Impaired cardiac reserve and exercise capacity in patients receiving long-term thyrotropin suppressive therapy with levothyroxine
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Impaired cardiac reserve and exercise capacity in patients receiving long-term thyrotropin suppressive therapy with levothyroxine
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Gullo D, Latina A, Frasca F, Squatrito S, Belfiore A, Vigneri R
* Seasonal variations in TSH serum levels in athyreotic patients under L-thyroxine replacement monotherapy (195 views)
Clin Endocrinol (ISSN: 0300-0664, 1365-2265, 0300-0664linking), 2017 Aug; 87(2): 207-215.
Impact Factor: 3.077
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Pace L, Klain M, Salvatore B, Nicolai E, Zampella E, Assante R, Pellegrino T, Storto G, Fonti R, Salvatore M
* Prognostic Role of 18F-FDG PET/CT in the Postoperative Evaluation of Differentiated Thyroid Cancer Patients (406 views)
Clin Nucl Med (ISSN: 0363-9762, 1536-0229, 1536-0229electronic), 2015 Feb; 40(2): 111-115.
Impact Factor: 4.278
View Export to BibTeX Export to EndNote
Pace L, Klain M, Salvatore B, Nicolai E, Zampella E, Assante R, Pellegrino T, Storto G, Fonti R, Salvatore M
* Prognostic Role Of 18f-Fluorodeoxyglucose Positron Emission Tomography/Ct In The Postoperative Evaluation Of Differentiated Thyroid Cancer Patients (264 views)
Clin Nucl Med (ISSN: 0363-9762, 1536-0229, 1536-0229electronic), 2015 Feb; 40(2): 111-115.
Impact Factor: 4.278
View Export to BibTeX Export to EndNote
Gallicchio R, Giacomobono S, Capacchione D, Nardelli A, Barbato F, Nappi A, Pellegrino T, Storto G
* Should patients with remnants from thyroid microcarcinoma really not be treated with iodine-131 ablation? (430 views)
Endocrine (ISSN: 1355-008x, 1355-008xlinking), 2013 Oct; 44(2): 426-433.
Impact Factor: 3.527
View Export to BibTeX Export to EndNote
Paolillo S, Rengo G, Pagano G, Pellegrino T, Savarese G, Femminella GD, Tuccillo M, Boemio A, Attena E, Formisano R, Petraglia L, Scopacasa F, Galasso G, Leosco D, Trimarco B, Cuocolo A, Perrone-Filardi P
* Impact of diabetes on cardiac sympathetic innervation in patients with heart failure: a 123I meta-iodobenzylguanidine (123I MIBG) scintigraphic study (313 views)
Diabetes Care (ISSN: 1935-5548, 0149-5992), 2013 Sep; 36(8): 2395-2401.
Impact Factor: 8.57
View Export to BibTeX Export to EndNote
Giallauria F, Acampa W, Ricci F, Gallicchio R, Xhoxhi E, Vitelli A, D'Agostino M, Lucci R, Vigorito C, Cuocolo A
* Effects of exercise training started within 2 weeks after acute myocardial infarction on myocardial perfusion and left ventricular function: A gated SPECT imaging study (386 views)
Eur J Prev Cardiol (ISSN: 2047-4873, 2047-4881), 2012 Dec; 19(6): 1410-1419.
Impact Factor: 2.675
View Export to BibTeX Export to EndNote
Cella L, Conson M, Caterino M, De Rosa N, Liuzzi R, Picardi M, Grimaldi F, Solla R, Farella A, Salvatore M, Pacelli R
* Thyroid V30 predicts radiation-induced hypothyroidism in patients treated with sequential chemo-radiotherapy for Hodgkin's lymphoma (490 views) (PDF 236 views)
Int J Radiat Oncol (ISSN: 0360-3016, 1879-355x, 1879-355xelectronic), 2012 Apr 1; 82(5): 1802-1808.
Impact Factor: 4.524
View Export to BibTeX Export to EndNote
Sorriento D, Santulli G, Del Giudice C, Anastasio A, Trimarco B, Iaccarino G
* Endothelial cells are able to synthesize and release catecholamines both in vitro and in vivo (423 views)
Hypertensionhypertension (ISSN: 0194-911x), 2012; 60(1): 129-136.
Impact Factor: 6.873
View Export to BibTeX Export to EndNote
Perrone-Filardi P, Paolillo S, Dellegrottaglie S, Gargiulo P, Savarese G, Marciano C, Casaretti L, Cecere M, Musella F, Pirozzi E, Parente A, Cuocolo A
* Assessment of cardiac sympathetic activity by MIBG imaging in patients with heart failure: a clinical appraisal (319 views)
Heart (ISSN: 1468-201x, 1355-6037), 2011 Nov; 97(22): 1828-1833.
Impact Factor: 4.223
View Export to BibTeX Export to EndNote
Manganelli F, Spadafora M, Varrella P, Peluso G, Sauro R, Di Lorenzo E, Rosato G, Daniele S, Cuocolo A
* Addition of atropine to submaximal exercise stress testing in patients evaluated for suspected ischaemia with SPECT imaging: a randomized, placebo-controlled trial (357 views)
Eur J Nucl Med (ISSN: 1619-7089, 1619-7070, 0340-6997), 2011 Feb; 38(2): 245-251.
Impact Factor: 4.991
View Export to BibTeX Export to EndNote
Chambery A, Severino V, Di Maro A, D'Aniello A, Ruvo M, Parente A
* Quantification of thyrotropin-releasing hormone by liquid chromatography-electrospray mass spectrometry (481 views)
Amino Acids (ISSN: 0939-4451, 1438-2199, 1438-2199electronic), 2010 Apr; 38(4): 1031-1041.
Impact Factor: 4.106
View Export to BibTeX Export to EndNote
Pace L, Nicolai E, Klain M, Salvatore M
* Diagnostic value of FDG PET/CT imaging (354 views)
Q J Nucl Med Mol Im (ISSN: 1824-4785, 1824-4478, 1824-4785linking), 2009; 53(5): 503-512.
Impact Factor: 1.724
View Export to BibTeX Export to EndNote
Pedone C, Di Pasquale G, Greco C, Gonzini L, Maggioni AP, Pavesi PC, Sabini A, Boccanelli A; In-Acs Outcome Investigators
* Prescription at discharge of recommended treatments for secondary prevention in patients with ST-segment elevation myocardial infarction according to reperfusion strategies. Results from the IN-ACS outcome study (449 views)
Acute Cardiac Care (ISSN: 1748-295x, 1748-2941), 2009; 11(4): 222-228.
Impact Factor: 0
View Export to BibTeX Export to EndNote
Leonardi D, Polizzotti N, Carta A, Gelsomino R, Sava L, Vigneri R, Calaciura F
* Longitudinal study of thyroid function in children with mild hyperthyrotropinemia at neonatal screening for congenital hypothyroidism (330 views)
Journal Of Clinical Endocrinology & Metabolism (ISSN: 0021-972x), 2008 Jul 1; 93(7): 2679-2685.
Impact Factor: 6.325
View Export to BibTeX Export to EndNote
Salvatore B, Paone G, Klain M, Storto G, Nicolai E, D'Amico D, Della Morte AM, Pace L, Salvatore M
* Fluorodeoxyglucose PET/CT in patients with differentiated thyroid cancer and elevated thyroglobulin after total thyroidectomy and 131I ablation (367 views)
Q J Nucl Med Mol Im (ISSN: 1824-4785, 1824-4478, 1824-4785linking), 2008 Mar; 52(1): 2-8.
Impact Factor: 1.724
View Export to BibTeX Export to EndNote
Pezzino V, Sipione C, Vigneri R
* Improving the diagnosis of central hypothyroidism (220 views)
J Endocrinol Invest (ISSN: 0391-4097, 1720-8386electronic, 0391-4097linking), 2008; 31(10): 939-939.
Impact Factor: 1.888
View Export to BibTeX Export to EndNote
Ferro A, Pellegrino T, Spinelli L, Acampa W, Petretta M, Cuocolo A
* Comparison Between Dobutamine Echocardiography and Single-Photon Emission Computed Tomography for Interpretive Reproducibility (334 views)
Am J Cardiol (ISSN: 0002-9149), 2007 Oct 15; 100(8): 1239-1244.
Impact Factor: 3.603
View Export to BibTeX Export to EndNote
Maestri R, Pinna G, Accardo A, Allegrini P, Balocchi R, D'ADDIO G, Ferrario M, Menicucci D, Porta A, Sassi R
* Nonlinear indices of heart rate variability in chronic heart failure patients: Redundancy and comparative clinical value (373 views)
J Cardiovasc Electrophysiol (ISSN: 1045-3873), 2007; 18(4): 425-433.
Impact Factor: 3.475
View Export to BibTeX Export to EndNote
Colao A, Di Somma C, Cuocolo A, Spinelli L, Acampa W, Spiezia S, Rota F, Savanelli MC, Lombardi G
* Does a gender-related effect of growth hormone (GH) replacement exist on cardiovascular risk factors, cardiac morphology, and performance and atherosclerosis? Results of a two-year open, prospective study in young adult men and women with severe GH deficiency (422 views)
J Clin Endocrinol Metab (ISSN: 0021-972x), 2005 Sep; 90(9): 5146-5155.
Impact Factor: 6.02
View Export to BibTeX Export to EndNote
Savastano S, Pivonello R, Acampa W, Salvatore M, Lombardi G, Colao A, Fenzi G
* Recombinant thyrotropin-induced orbital uptake of [In-111-diethylenetriamine-pentacetic acid-D-phe(1)]octreotide in a patient with inactive Graves' ophthalmopathy (308 views)
Journal Of Clinical Endocrinology & Metabolism (ISSN: 0021-972x), 2005 Apr; 90(4): 2440-2444.
Impact Factor: 6.02
View Export to BibTeX Export to EndNote
Hesse B, Tagil K, Cuocolo A, Anagnostopoulos C, Bardies M, Bax J, Bengel F, Busemann Sokole E, Davies G, Dondi M, Edenbrandt L, Franken P, Kjaer A, Knuuti J, Lassmann M, Ljungberg M, Marcassa C, Marie PY, Mckiddie F, O'connor M, Prvuolovich E, Underwood R
* 3. 0 T perfusion MR imaging (694 views)
Rivista Di Neuroradiologia (ISSN: 1120-9976), 2004; 17(6): 807-812.
Impact Factor: 0.023
View Export to BibTeX Export to EndNote
Biondi B, Palmieri EA, Pagano L, Klain M, Scherillo G, Salvatore M, Fenzi G, Lombardi G, Fazio S
* Cardiovascular safety of acute recombinant human thyrotropin administration to patients monitored for differentiated thyroid cancer (388 views)
J Clin Endocrinol Metab (ISSN: 0021-972x), 2003 Jan; 88(1): 211-214.
Impact Factor: 5.873
View Export to BibTeX Export to EndNote
Colao A, Cuocolo A, Di Somma C, Cerbone G, Della Morte A, Nicolai E, Lucci R, Salvatore M, Lombardi G
Impaired cardiac performance in elderly patients with growth hormone deficiency (344 views)
J Clin Endocrinol Metab (ISSN: 0021-972x), 1999 Nov; 84(11): 3950-3955.
Impact Factor: 5.805
View Export to BibTeX Export to EndNote
Marotta T, Ferrara LA, Di Marino L, Mancini M, Annuzzi G, Russo O, D'Orta G, Lucarelli C, Rossi F
Factors affecting lipoprotein lipase in hypertensive patients (375 views)
Metab Clin Exp (ISSN: 0026-0495, 1532-8600), 1995 Jun; 44(6): 712-718.
Impact Factor: 1.681
View Export to BibTeX Export to EndNote
Greco AM, de Franciscis P, Bozza P, Salvatore M
Thyroid function and lipid metabolism in rats treated with lithium and cholesterol deficient Nath diet (685 views)
Boll Soc Ital Biol Sper (ISSN: 0037-8771), 1979 Dec 30; 55(24): 2589-2595.
Impact Factor: 0
View Export to BibTeX Export to EndNote
* Seasonal variations in TSH serum levels in athyreotic patients under L-thyroxine replacement monotherapy (195 views)
Clin Endocrinol (ISSN: 0300-0664, 1365-2265, 0300-0664linking), 2017 Aug; 87(2): 207-215.
Impact Factor: 3.077
View Export to BibTeX Export to EndNote
Pace L, Klain M, Salvatore B, Nicolai E, Zampella E, Assante R, Pellegrino T, Storto G, Fonti R, Salvatore M
* Prognostic Role of 18F-FDG PET/CT in the Postoperative Evaluation of Differentiated Thyroid Cancer Patients (406 views)
Clin Nucl Med (ISSN: 0363-9762, 1536-0229, 1536-0229electronic), 2015 Feb; 40(2): 111-115.
Impact Factor: 4.278
View Export to BibTeX Export to EndNote
Pace L, Klain M, Salvatore B, Nicolai E, Zampella E, Assante R, Pellegrino T, Storto G, Fonti R, Salvatore M
* Prognostic Role Of 18f-Fluorodeoxyglucose Positron Emission Tomography/Ct In The Postoperative Evaluation Of Differentiated Thyroid Cancer Patients (264 views)
Clin Nucl Med (ISSN: 0363-9762, 1536-0229, 1536-0229electronic), 2015 Feb; 40(2): 111-115.
Impact Factor: 4.278
View Export to BibTeX Export to EndNote
Gallicchio R, Giacomobono S, Capacchione D, Nardelli A, Barbato F, Nappi A, Pellegrino T, Storto G
* Should patients with remnants from thyroid microcarcinoma really not be treated with iodine-131 ablation? (430 views)
Endocrine (ISSN: 1355-008x, 1355-008xlinking), 2013 Oct; 44(2): 426-433.
Impact Factor: 3.527
View Export to BibTeX Export to EndNote
Paolillo S, Rengo G, Pagano G, Pellegrino T, Savarese G, Femminella GD, Tuccillo M, Boemio A, Attena E, Formisano R, Petraglia L, Scopacasa F, Galasso G, Leosco D, Trimarco B, Cuocolo A, Perrone-Filardi P
* Impact of diabetes on cardiac sympathetic innervation in patients with heart failure: a 123I meta-iodobenzylguanidine (123I MIBG) scintigraphic study (313 views)
Diabetes Care (ISSN: 1935-5548, 0149-5992), 2013 Sep; 36(8): 2395-2401.
Impact Factor: 8.57
View Export to BibTeX Export to EndNote
Giallauria F, Acampa W, Ricci F, Gallicchio R, Xhoxhi E, Vitelli A, D'Agostino M, Lucci R, Vigorito C, Cuocolo A
* Effects of exercise training started within 2 weeks after acute myocardial infarction on myocardial perfusion and left ventricular function: A gated SPECT imaging study (386 views)
Eur J Prev Cardiol (ISSN: 2047-4873, 2047-4881), 2012 Dec; 19(6): 1410-1419.
Impact Factor: 2.675
View Export to BibTeX Export to EndNote
Cella L, Conson M, Caterino M, De Rosa N, Liuzzi R, Picardi M, Grimaldi F, Solla R, Farella A, Salvatore M, Pacelli R
* Thyroid V30 predicts radiation-induced hypothyroidism in patients treated with sequential chemo-radiotherapy for Hodgkin's lymphoma (490 views) (PDF 236 views)
Int J Radiat Oncol (ISSN: 0360-3016, 1879-355x, 1879-355xelectronic), 2012 Apr 1; 82(5): 1802-1808.
Impact Factor: 4.524
View Export to BibTeX Export to EndNote
Sorriento D, Santulli G, Del Giudice C, Anastasio A, Trimarco B, Iaccarino G
* Endothelial cells are able to synthesize and release catecholamines both in vitro and in vivo (423 views)
Hypertensionhypertension (ISSN: 0194-911x), 2012; 60(1): 129-136.
Impact Factor: 6.873
View Export to BibTeX Export to EndNote
Perrone-Filardi P, Paolillo S, Dellegrottaglie S, Gargiulo P, Savarese G, Marciano C, Casaretti L, Cecere M, Musella F, Pirozzi E, Parente A, Cuocolo A
* Assessment of cardiac sympathetic activity by MIBG imaging in patients with heart failure: a clinical appraisal (319 views)
Heart (ISSN: 1468-201x, 1355-6037), 2011 Nov; 97(22): 1828-1833.
Impact Factor: 4.223
View Export to BibTeX Export to EndNote
Manganelli F, Spadafora M, Varrella P, Peluso G, Sauro R, Di Lorenzo E, Rosato G, Daniele S, Cuocolo A
* Addition of atropine to submaximal exercise stress testing in patients evaluated for suspected ischaemia with SPECT imaging: a randomized, placebo-controlled trial (357 views)
Eur J Nucl Med (ISSN: 1619-7089, 1619-7070, 0340-6997), 2011 Feb; 38(2): 245-251.
Impact Factor: 4.991
View Export to BibTeX Export to EndNote
Chambery A, Severino V, Di Maro A, D'Aniello A, Ruvo M, Parente A
* Quantification of thyrotropin-releasing hormone by liquid chromatography-electrospray mass spectrometry (481 views)
Amino Acids (ISSN: 0939-4451, 1438-2199, 1438-2199electronic), 2010 Apr; 38(4): 1031-1041.
Impact Factor: 4.106
View Export to BibTeX Export to EndNote
Pace L, Nicolai E, Klain M, Salvatore M
* Diagnostic value of FDG PET/CT imaging (354 views)
Q J Nucl Med Mol Im (ISSN: 1824-4785, 1824-4478, 1824-4785linking), 2009; 53(5): 503-512.
Impact Factor: 1.724
View Export to BibTeX Export to EndNote
Pedone C, Di Pasquale G, Greco C, Gonzini L, Maggioni AP, Pavesi PC, Sabini A, Boccanelli A; In-Acs Outcome Investigators
* Prescription at discharge of recommended treatments for secondary prevention in patients with ST-segment elevation myocardial infarction according to reperfusion strategies. Results from the IN-ACS outcome study (449 views)
Acute Cardiac Care (ISSN: 1748-295x, 1748-2941), 2009; 11(4): 222-228.
Impact Factor: 0
View Export to BibTeX Export to EndNote
Leonardi D, Polizzotti N, Carta A, Gelsomino R, Sava L, Vigneri R, Calaciura F
* Longitudinal study of thyroid function in children with mild hyperthyrotropinemia at neonatal screening for congenital hypothyroidism (330 views)
Journal Of Clinical Endocrinology & Metabolism (ISSN: 0021-972x), 2008 Jul 1; 93(7): 2679-2685.
Impact Factor: 6.325
View Export to BibTeX Export to EndNote
Salvatore B, Paone G, Klain M, Storto G, Nicolai E, D'Amico D, Della Morte AM, Pace L, Salvatore M
* Fluorodeoxyglucose PET/CT in patients with differentiated thyroid cancer and elevated thyroglobulin after total thyroidectomy and 131I ablation (367 views)
Q J Nucl Med Mol Im (ISSN: 1824-4785, 1824-4478, 1824-4785linking), 2008 Mar; 52(1): 2-8.
Impact Factor: 1.724
View Export to BibTeX Export to EndNote
Pezzino V, Sipione C, Vigneri R
* Improving the diagnosis of central hypothyroidism (220 views)
J Endocrinol Invest (ISSN: 0391-4097, 1720-8386electronic, 0391-4097linking), 2008; 31(10): 939-939.
Impact Factor: 1.888
View Export to BibTeX Export to EndNote
Ferro A, Pellegrino T, Spinelli L, Acampa W, Petretta M, Cuocolo A
* Comparison Between Dobutamine Echocardiography and Single-Photon Emission Computed Tomography for Interpretive Reproducibility (334 views)
Am J Cardiol (ISSN: 0002-9149), 2007 Oct 15; 100(8): 1239-1244.
Impact Factor: 3.603
View Export to BibTeX Export to EndNote
Maestri R, Pinna G, Accardo A, Allegrini P, Balocchi R, D'ADDIO G, Ferrario M, Menicucci D, Porta A, Sassi R
* Nonlinear indices of heart rate variability in chronic heart failure patients: Redundancy and comparative clinical value (373 views)
J Cardiovasc Electrophysiol (ISSN: 1045-3873), 2007; 18(4): 425-433.
Impact Factor: 3.475
View Export to BibTeX Export to EndNote
Colao A, Di Somma C, Cuocolo A, Spinelli L, Acampa W, Spiezia S, Rota F, Savanelli MC, Lombardi G
* Does a gender-related effect of growth hormone (GH) replacement exist on cardiovascular risk factors, cardiac morphology, and performance and atherosclerosis? Results of a two-year open, prospective study in young adult men and women with severe GH deficiency (422 views)
J Clin Endocrinol Metab (ISSN: 0021-972x), 2005 Sep; 90(9): 5146-5155.
Impact Factor: 6.02
View Export to BibTeX Export to EndNote
Savastano S, Pivonello R, Acampa W, Salvatore M, Lombardi G, Colao A, Fenzi G
* Recombinant thyrotropin-induced orbital uptake of [In-111-diethylenetriamine-pentacetic acid-D-phe(1)]octreotide in a patient with inactive Graves' ophthalmopathy (308 views)
Journal Of Clinical Endocrinology & Metabolism (ISSN: 0021-972x), 2005 Apr; 90(4): 2440-2444.
Impact Factor: 6.02
View Export to BibTeX Export to EndNote
Hesse B, Tagil K, Cuocolo A, Anagnostopoulos C, Bardies M, Bax J, Bengel F, Busemann Sokole E, Davies G, Dondi M, Edenbrandt L, Franken P, Kjaer A, Knuuti J, Lassmann M, Ljungberg M, Marcassa C, Marie PY, Mckiddie F, O'connor M, Prvuolovich E, Underwood R
* 3. 0 T perfusion MR imaging (694 views)
Rivista Di Neuroradiologia (ISSN: 1120-9976), 2004; 17(6): 807-812.
Impact Factor: 0.023
View Export to BibTeX Export to EndNote
Biondi B, Palmieri EA, Pagano L, Klain M, Scherillo G, Salvatore M, Fenzi G, Lombardi G, Fazio S
* Cardiovascular safety of acute recombinant human thyrotropin administration to patients monitored for differentiated thyroid cancer (388 views)
J Clin Endocrinol Metab (ISSN: 0021-972x), 2003 Jan; 88(1): 211-214.
Impact Factor: 5.873
View Export to BibTeX Export to EndNote
Colao A, Cuocolo A, Di Somma C, Cerbone G, Della Morte A, Nicolai E, Lucci R, Salvatore M, Lombardi G
Impaired cardiac performance in elderly patients with growth hormone deficiency (344 views)
J Clin Endocrinol Metab (ISSN: 0021-972x), 1999 Nov; 84(11): 3950-3955.
Impact Factor: 5.805
View Export to BibTeX Export to EndNote
Marotta T, Ferrara LA, Di Marino L, Mancini M, Annuzzi G, Russo O, D'Orta G, Lucarelli C, Rossi F
Factors affecting lipoprotein lipase in hypertensive patients (375 views)
Metab Clin Exp (ISSN: 0026-0495, 1532-8600), 1995 Jun; 44(6): 712-718.
Impact Factor: 1.681
View Export to BibTeX Export to EndNote
Greco AM, de Franciscis P, Bozza P, Salvatore M
Thyroid function and lipid metabolism in rats treated with lithium and cholesterol deficient Nath diet (685 views)
Boll Soc Ital Biol Sper (ISSN: 0037-8771), 1979 Dec 30; 55(24): 2589-2595.
Impact Factor: 0
View Export to BibTeX Export to EndNote
25 Records (24 excluding Abstracts).
Total impact factor: 95.283 (93.395 excluding Abstracts).
Total 5 year impact factor: 83.62 (81.489 excluding Abstracts).
Total impact factor: 95.283 (93.395 excluding Abstracts).
Total 5 year impact factor: 83.62 (81.489 excluding Abstracts).
336 views. Last view on Thursday 26 January 2023, 9:00:45
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