Survival benefit after revascularization is independent of left ventricular ejection fraction improvement in patients with previous myocardial infarction and viable myocardium
Survival benefit after revascularization is independent of left ventricular ejection fraction improvement in patients with previous myocardial infarction and viable myocardium(282 views) Acampa W, Petretta M, Spinelli L, Ibello F, De Lauro F, Sansone V, Salvatore M, Cuocolo A
Dept. Biomorphological Funct. Sci., Inst. Biostructure Bioimages N., University Federico II, Naples, Italy
Dept. Clin. Med., Cardiovasc. I., University Federico II, Naples, Italy
IRCCS Neuromed, Pozzilli, Italy
References: Vanoverschelde, J.L., Wijns, W., Borgers, M., Heyndrickx, G., Depre, C., Flameng, W., Chronic myocardial hibernation in humans: From bedside to bench (1997) Circulation, 95, pp. 1961-197
Cuocolo, A., Petretta, M., Nicolai, E., Pace, L., Bonaduce, D., Salvatore, M., Successful coronary revascularization improves prognosis in patients with previous myocardial infarction and evidence of viable myocardium at thallium-201 imaging (1998) Eur J Nucl Med, 25, pp. 60-68
Allman, K.C., Shaw, L.J., Hachamovitch, R., Udelson, J.E., Myocardial viability testing and impact of revascularization on prognosis in patients with coronary artery disease and left ventricular dysfunction: A meta-analysis (2002) J Am Coll Cardiol, 39, pp. 1151-1158
Di Carli, M.F., Assessment of myocardial viability after myocardial infarction (2002) J Nucl Cardiol, 9, pp. 229-235
Kaul, S., Response of dysfunctional myocardium to dobutamine: The eyes see what the mind knows (1996) J Am Coll Cardiol, 27, pp. 1608-1611
Bonow, R.O., Identification of viable myocardium (1996) Circulation, 94, pp. 2674-2680
Bonow, R.O., Myocardial viability and prognosis in patients with ischemic left ventricular dysfunction (2002) J Am Coll Cardiol, 39, pp. 1159-1162
Marwick, T.H., Zuchowski, C., Lauer, M.S., Secknus, M.A., Williams, J., Lytle, B.W., Functional status and quality of life in patients with heart failure undergoing coronary bypass surgery after assessment of myocardial viability (1999) J Am Coll Cardiol, 33, pp. 750-758
Di Carli, M.F., Asgarzadie, F., Schelbert, H.R., Brunken, R.C., Laks, H., Phelps, M.E., Quantitative relation between myocardial viability and improvement in heart failure symptoms after revascularization in patients with ischemic cardiomyopathy (1995) Circulation, 92, pp. 436-444
Bax, J.J., Visser, F.C., Poldermans, D., Elhendy, A., Cornel, J.H., Boersma, E., Relationship between preoperative viability and postoperative improvement in LVEF and heart failure symptoms (2001) J Nucl Med, 42, pp. 79-86
Bax, J.J., Poldermans, D., Elhendy, A., Cornel, J.H., Boersma, E., Rambaldi, R., Improvement of left ventricular ejection fraction, heart failure symptoms and prognosis after revascularization in patients with chronic coronary artery disease and viable myocardium detected by dobutamine stress echocardiography (1999) J Am Coll Cardiol, 34, pp. 163-169
Samady, H., Elefteriades, J.A., Abbott, B.G., Mattera, J.A., McPherson, C.A., Wackers, F.J., Failure to improve left ventricular function after coronary revascularization for ischemic cardiomyopathy is not associated with worse outcome (1999) Circulation, 100, pp. 1298-1304
Acampa, W., Petretta, M., Florimonte, L., Scotto Di Santolo, M., Cuocolo, A., Sestamibi SPECT in the detection of myocardial viability in patients with chronic ischemic left ventricular dysfunction: Comparison between visual and quantitative analysis (2000) J Nucl Cardiol, 7, pp. 406-413
Spinelli, L., Petretta, M., Acampa, W., He, W., Petretta, A., Bonaduce, D., Prognostic value of combined assessment of regional left ventricular function and myocardial perfusion by dobutamine and rest gated SPECT in patients with uncomplicated acute myocardial infarction (2003) J Nucl Med, 44, pp. 1023-1029
Cox, D.R., Regression models and life table (1972) J R Stat Soc B, 34, pp. 187-220
Norasis, M.J., (1993) SPSS for Windows: Advanced Statistics, Release 6.0, pp. 1-30. , Chicago, IL: SPSS Inc
Pagley, P.R., Beller, G.A., Watson, D.D., Gimple, L.W., Ragosta, M., Improved outcome after coronary bypass surgery in patients with ischemic cardiomyopathy and residual myocardial viability (1997) Circulation, 96, pp. 793-800
Risk stratification and survival after myocardial infarction (1983) N Engl J Med, 309, pp. 331-336
Muhlbaier, L.H., Pryor, D.B., Rankin, J.S., Smith, L.R., Mark, D.B., Jones, R.H., Observational comparison of event-free survival with medical and surgical therapy in patients with coronary artery disease. 20 Years of follow-up (1992) Circulation, 86 (2 SUPPL.), pp. II198-II204
Emond, M., Mock, M.B., Davis, K.B., Fisher, L.D., Holmes Jr., D.R., Chairman, B.R., Long-term survival of medically treated patients in the Coronary Artery Surgery Study (CASS) Registry (1994) Circulation, 90, pp. 2645-2657
Lombardo, A., Loperfido, F., Trani, C., Pennestri, F., Rossi, E., Giordano, A., Contractile reserve of dysfunctional myocardium after revascularization: A dobutamine stress echocardiography study (1997) J Am Coll Cardiol, 30, pp. 633-640
Afridi, I., Qureshi, U., Kopelen, H.A., Winters, W.L., Zoghbi, W.A., Serial changes in response of hibernating myocardium to inotropic stimulation after revascularization: A dobutamine echocardiographic study (1997) J Am Coll Cardiol, 30, pp. 1233-1240
Kaul, S., There may be more to myocardial viability than meets the eye (1995) Circulation, 92, pp. 2790-2793
Di Carli, M.F., The quest for myocardial viability: Is there a role for nitrate-enhanced imaging? (2003) J Nucl Cardiol, 10, pp. 696-699
Vanoverschelde, J. L., Wijns, W., Borgers, M., Heyndrickx, G., Depre, C., Flameng, W., Chronic myocardial hibernation in humans: From bedside to bench (1997) Circulation, 95, pp. 1961-197
Allman, K. C., Shaw, L. J., Hachamovitch, R., Udelson, J. E., Myocardial viability testing and impact of revascularization on prognosis in patients with coronary artery disease and left ventricular dysfunction: A meta-analysis (2002) J Am Coll Cardiol, 39, pp. 1151-1158
Di Carli, M. F., Assessment of myocardial viability after myocardial infarction (2002) J Nucl Cardiol, 9, pp. 229-235
Bonow, R. O., Identification of viable myocardium (1996) Circulation, 94, pp. 2674-2680
Bonow, R. O., Myocardial viability and prognosis in patients with ischemic left ventricular dysfunction (2002) J Am Coll Cardiol, 39, pp. 1159-1162
Marwick, T. H., Zuchowski, C., Lauer, M. S., Secknus, M. A., Williams, J., Lytle, B. W., Functional status and quality of life in patients with heart failure undergoing coronary bypass surgery after assessment of myocardial viability (1999) J Am Coll Cardiol, 33, pp. 750-758
Bax, J. J., Visser, F. C., Poldermans, D., Elhendy, A., Cornel, J. H., Boersma, E., Relationship between preoperative viability and postoperative improvement in LVEF and heart failure symptoms (2001) J Nucl Med, 42, pp. 79-86
Bax, J. J., Poldermans, D., Elhendy, A., Cornel, J. H., Boersma, E., Rambaldi, R., Improvement of left ventricular ejection fraction, heart failure symptoms and prognosis after revascularization in patients with chronic coronary artery disease and viable myocardium detected by dobutamine stress echocardiography (1999) J Am Coll Cardiol, 34, pp. 163-169
Cox, D. R., Regression models and life table (1972) J R Stat Soc B, 34, pp. 187-220
Norasis, M. J., (1993) SPSS for Windows: Advanced Statistics, Release 6. 0, pp. 1-30. , Chicago, IL: SPSS Inc
Pagley, P. R., Beller, G. A., Watson, D. D., Gimple, L. W., Ragosta, M., Improved outcome after coronary bypass surgery in patients with ischemic cardiomyopathy and residual myocardial viability (1997) Circulation, 96, pp. 793-800
Muhlbaier, L. H., Pryor, D. B., Rankin, J. S., Smith, L. R., Mark, D. B., Jones, R. H., Observational comparison of event-free survival with medical and surgical therapy in patients with coronary artery disease. 20 Years of follow-up (1992) Circulation, 86 (2 SUPPL.), pp. II198-II204
Di Carli, M. F., The quest for myocardial viability: Is there a role for nitrate-enhanced imaging? (2003) J Nucl Cardiol, 10, pp. 696-699
Survival benefit after revascularization is independent of left ventricular ejection fraction improvement in patients with previous myocardial infarction and viable myocardium
Purpose: This study was designed to assess the relationships among myocardial viability, changes in left ventricular (LV) ejection fraction after coronary revascularization and long-term event-free survival in patients with previous myocardial infarction and LV dysfunction. Methods: We studied 253 patients with previous myocardial infarction and evidence of dysfunctional viable myocardium as assessed by echocardiography and 99mTc-sestamibi imaging. Coronary revascularization was performed in 142 patients, while 111 were medically treated. In revascularized patients, echocardiography was repeated 12 months later to detect LV ejection fraction improvement, defined as an increase of ≥5% compared with baseline. All patients were followed for a mean period of 52±29 months. Cardiac death and non-fatal myocardial infarction were considered as events. Results: Event-free survival was higher in revascularized than in medically treated patients (P
Survival benefit after revascularization is independent of left ventricular ejection fraction improvement in patients with previous myocardial infarction and viable myocardium
Survival benefit after revascularization is independent of left ventricular ejection fraction improvement in patients with previous myocardial infarction and viable myocardium