Crystal structure of Trematomus newnesi haemoglobin re-opens the Root effect question (435 views)
J Mol Biol (ISSN: 0022-2836, 1089-8638, 1089-8638electronic), 1999 Apr 16; 287(5): 897-906.
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Paper type: Journal Article,
Impact factor: 5.501, 5-year impact factor: 4.733
Url: http://www.scopus.com/inward/record.url?eid=2-s2.0-0033574669&partnerID=40&md5=b079e1b5d2779a736f6991fd0b587873
Keywords: Antarctic Fish, Haemoglobin, Root Effect, Trematomus Newnesi, X-Ray Structure, Hemoglobin, Mutant Protein, Oxygen, Article, Crystal Structure, Nonhuman, Oxygen Affinity, Priority Journal, Sequence Homology, Animals, Crystallography, Models, Molecular, Protein Conformation, Protein Structure, Tertiary, Amino Acid,
Affiliations:
Dipto. Chim. Dell'Univ. Napoli F., Via Mezzocannone, 4, I-80134, Napoli, Italy
Ist. Biochim. Delle Proteine Ed E., CNR, Via Marconi 10, I-80125, Napoli, Italy
Department of Biochemistry, University of Leicester, Leicester, LE1 7RH, United Kingdom
References:
Baldwin, J.M., Chothia, C., Haemoglobin: The structural changes related to ligand binding and its allosteric mechanism (1979) J. Mol. Biol., 129, pp. 175-22
Brünger, A.T., (1992) X-PLOR Manual, Version 3.1, , New Haven: Yale University Press
Camardella, L., Caruso, C., D'Avino, R., Di Prisco, G., Rutigliano, B., Tamburrini, M., Fermi, G., Perutz, M.F., Haemoglobin of the Antarctic fish Pagothenia bernacchii. Amino acid sequence, oxygen equilibria and crystal structure of its carbonmonoxy derivative (1992) J. Mol. Biol., 224, pp. 449-460
D'Avino, R., Caruso, C., Tamburrini, M., Romano, M., Rutigliano, B., Polverino De Laureto, P., Camardella, L., Di Prisco, G., Molecular characterization of the functionally distinct haemoglobins of the Antarctic fish Trematomus newnesi (1994) J. Biol. Chem., 269, pp. 9675-9681
Derewenda, Z.D., Dodson, G.G., Emsley, P., Harris, D., Nagai, K., Perutz, M.F., Reynard, J.-P., Stereochemistry of carbon monoxide binding to normal human adult and Cowtown haemoglobin (1990) J. Mol. Biol., 211, pp. 515-519
Di Prisco, G., Physiological and biochemical adaptations in fish to a cold marine environment (1997) Antarctic Communities, Species, Structure and Survival, pp. 251-260. , B. Battaglia, J. Valencia, & D. W. H. Walton. Cambridge: Cambridge University Press
Di Prisco, G., Tamburrini, M., D'Avino, R., Oxygen transport systems in extreme environments: Multiplicity and structure/function relationships in haemoglobin of Antarctic fish (1997) Cold Ocean Physiology, pp. 143-165. , H. O. Pörtner, & R. C. Playle. Cambridge: Cambridge University Press
Hendrikson, W.A., Stereochemically restrained refinement of macromolecular structures (1985) Methods Enzymol., 115, pp. 252-270
Ito, N., Komiyama, N.H., Fermi, G., Structure of deoxyhaemoglobin of the Antarctic fish Pagothenia bernacchii with an analysis of the structural basis of the Root effect by comparison of the liganded and unliganded haemoglobin structures (1995) J. Mol. Biol., 250, pp. 648-658
Jones, T.A., Interactive computer graphics: FRODO (1985) Methods. Enzymol., 115, pp. 157-171
Jones, T.A., Zou, J.-Y., Cowan, S.W., Kjeldgaard, M., Improved methods for building protein models in electron-density maps and the location of errors in these models (1991) Acta Crystallog. Sect. a, 47, pp. 110-119
Kraulis, P.J., MOLSCRIPT: A program to produce both detailed and schematic plots of protein structures (1991) J. Appl. Crystallog., 24, pp. 946-950
Laskowskoi, R.A., MacArthur, M.W., Moss, D.S., Thornton, J.M., PROCHECK: A program to check for stereochemical quality of protein structures (1993) J. Appl. Crystallog., 26, pp. 283-291
Leslie, A.G.W., Recent changes to the MOSFLM package for processing film and image plate data (1992) CCP4 and ESF-EACMB Newsletter on Protein Crystallography No.26, , Warrington: SERCDaresbury Laboratory
Merrit, E., Murphy, M., RASTER3D version 2.0: A program for photorealistic molecular graphics (1994) Acta Crystallog. Sect. D, 50, pp. 869-879
Mylvaganam, S.E., Bonaventura, C., Bonaventura, J., Getzoff, E.D., Structural basis for the Root effect in haemoglobin (1996) Nature Struct. Biol., 3, pp. 275-283
Perutz, M.F., Cause of the Root effect in fish haemoglobin (1996) Nature Struct. Biol., 3, pp. 211-212
Perutz, M.F., Brunori, M., Stereochemistry of cooperative effects in fish and amphibian haemoglobins (1982) Nature, 299, pp. 421-426
Perutz, M.F., Fermi, G., Luisi, B., Shaanan, B., Liddington, R., Stereochemistry of cooperative mechanism in hemoglobin (1987) Acc. Chem. Res., 20, pp. 309-321
Shih, D.T., Luisi, B.F., Miyazaky, G., Perutz, M.F., Nagai, K., A mutagenic study of the allosteric linkage of His(HC3)146 β in haemoglobin (1993) J. Mol. Biol., 230, pp. 1291-1296
Tame, J.R.H., Wilson, J.C., Weber, R.E., The crystal structures of Trout Hb I in the deoxy and carbonmonoxy forms (1996) J. Mol. Biol., 259, pp. 749-760
Weber, R.E., Jessen, T.-H., Malte, H., Tame, J., Mutant hemoglobins (α119-Ala and β55-Ser): Functions related to high altitude respiration in geese (1993) J. Appl. Physiol., 75, pp. 2646-2655
Zhang, J., Hua, Z., Tame, J.R.H., Zhang, G.L.R., Gu, X., The crystal structure of a high oxygen affinity species of haemoglobin (1996) J. Mol. Biol., 255, pp. 484-493
Baldwin, J. M., Chothia, C., Haemoglobin: The structural changes related to ligand binding and its allosteric mechanism (1979) J. Mol. Biol., 129, pp. 175-22
Br nger, A. T., (1992) X-PLOR Manual, Version 3. 1, , New Haven: Yale University Press
Derewenda, Z. D., Dodson, G. G., Emsley, P., Harris, D., Nagai, K., Perutz, M. F., Reynard, J. -P., Stereochemistry of carbon monoxide binding to normal human adult and Cowtown haemoglobin (1990) J. Mol. Biol., 211, pp. 515-519
Hendrikson, W. A., Stereochemically restrained refinement of macromolecular structures (1985) Methods Enzymol., 115, pp. 252-270
Jones, T. A., Interactive computer graphics: FRODO (1985) Methods. Enzymol., 115, pp. 157-171
Jones, T. A., Zou, J. -Y., Cowan, S. W., Kjeldgaard, M., Improved methods for building protein models in electron-density maps and the location of errors in these models (1991) Acta Crystallog. Sect. a, 47, pp. 110-119
Kraulis, P. J., MOLSCRIPT: A program to produce both detailed and schematic plots of protein structures (1991) J. Appl. Crystallog., 24, pp. 946-950
Laskowskoi, R. A., MacArthur, M. W., Moss, D. S., Thornton, J. M., PROCHECK: A program to check for stereochemical quality of protein structures (1993) J. Appl. Crystallog., 26, pp. 283-291
Leslie, A. G. W., Recent changes to the MOSFLM package for processing film and image plate data (1992) CCP4 and ESF-EACMB Newsletter on Protein Crystallography No. 26, , Warrington: SERCDaresbury Laboratory
Mylvaganam, S. E., Bonaventura, C., Bonaventura, J., Getzoff, E. D., Structural basis for the Root effect in haemoglobin (1996) Nature Struct. Biol., 3, pp. 275-283
Perutz, M. F., Cause of the Root effect in fish haemoglobin (1996) Nature Struct. Biol., 3, pp. 211-212
Perutz, M. F., Brunori, M., Stereochemistry of cooperative effects in fish and amphibian haemoglobins (1982) Nature, 299, pp. 421-426
Perutz, M. F., Fermi, G., Luisi, B., Shaanan, B., Liddington, R., Stereochemistry of cooperative mechanism in hemoglobin (1987) Acc. Chem. Res., 20, pp. 309-321
Shih, D. T., Luisi, B. F., Miyazaky, G., Perutz, M. F., Nagai, K., A mutagenic study of the allosteric linkage of His (HC3) 146 in haemoglobin (1993) J. Mol. Biol., 230, pp. 1291-1296
Tame, J. R. H., Wilson, J. C., Weber, R. E., The crystal structures of Trout Hb I in the deoxy and carbonmonoxy forms (1996) J. Mol. Biol., 259, pp. 749-760
Weber, R. E., Jessen, T. -H., Malte, H., Tame, J., Mutant hemoglobins (119-Ala and 55-Ser): Functions related to high altitude respiration in geese (1993) J. Appl. Physiol., 75, pp. 2646-2655
J Mol Biol (ISSN: 0022-2836, 1089-8638, 1089-8638electronic), 1999 Apr 16; 287(5): 897-906.
Export to BibTeX Export to EndNote
Paper type: Journal Article,
Impact factor: 5.501, 5-year impact factor: 4.733
Url: http://www.scopus.com/inward/record.url?eid=2-s2.0-0033574669&partnerID=40&md5=b079e1b5d2779a736f6991fd0b587873
Keywords: Antarctic Fish, Haemoglobin, Root Effect, Trematomus Newnesi, X-Ray Structure, Hemoglobin, Mutant Protein, Oxygen, Article, Crystal Structure, Nonhuman, Oxygen Affinity, Priority Journal, Sequence Homology, Animals, Crystallography, Models, Molecular, Protein Conformation, Protein Structure, Tertiary, Amino Acid,
Affiliations:
Dipto. Chim. Dell'Univ. Napoli F., Via Mezzocannone, 4, I-80134, Napoli, Italy
Ist. Biochim. Delle Proteine Ed E., CNR, Via Marconi 10, I-80125, Napoli, Italy
Department of Biochemistry, University of Leicester, Leicester, LE1 7RH, United Kingdom
References:
Baldwin, J.M., Chothia, C., Haemoglobin: The structural changes related to ligand binding and its allosteric mechanism (1979) J. Mol. Biol., 129, pp. 175-22
Brünger, A.T., (1992) X-PLOR Manual, Version 3.1, , New Haven: Yale University Press
Camardella, L., Caruso, C., D'Avino, R., Di Prisco, G., Rutigliano, B., Tamburrini, M., Fermi, G., Perutz, M.F., Haemoglobin of the Antarctic fish Pagothenia bernacchii. Amino acid sequence, oxygen equilibria and crystal structure of its carbonmonoxy derivative (1992) J. Mol. Biol., 224, pp. 449-460
D'Avino, R., Caruso, C., Tamburrini, M., Romano, M., Rutigliano, B., Polverino De Laureto, P., Camardella, L., Di Prisco, G., Molecular characterization of the functionally distinct haemoglobins of the Antarctic fish Trematomus newnesi (1994) J. Biol. Chem., 269, pp. 9675-9681
Derewenda, Z.D., Dodson, G.G., Emsley, P., Harris, D., Nagai, K., Perutz, M.F., Reynard, J.-P., Stereochemistry of carbon monoxide binding to normal human adult and Cowtown haemoglobin (1990) J. Mol. Biol., 211, pp. 515-519
Di Prisco, G., Physiological and biochemical adaptations in fish to a cold marine environment (1997) Antarctic Communities, Species, Structure and Survival, pp. 251-260. , B. Battaglia, J. Valencia, & D. W. H. Walton. Cambridge: Cambridge University Press
Di Prisco, G., Tamburrini, M., D'Avino, R., Oxygen transport systems in extreme environments: Multiplicity and structure/function relationships in haemoglobin of Antarctic fish (1997) Cold Ocean Physiology, pp. 143-165. , H. O. Pörtner, & R. C. Playle. Cambridge: Cambridge University Press
Hendrikson, W.A., Stereochemically restrained refinement of macromolecular structures (1985) Methods Enzymol., 115, pp. 252-270
Ito, N., Komiyama, N.H., Fermi, G., Structure of deoxyhaemoglobin of the Antarctic fish Pagothenia bernacchii with an analysis of the structural basis of the Root effect by comparison of the liganded and unliganded haemoglobin structures (1995) J. Mol. Biol., 250, pp. 648-658
Jones, T.A., Interactive computer graphics: FRODO (1985) Methods. Enzymol., 115, pp. 157-171
Jones, T.A., Zou, J.-Y., Cowan, S.W., Kjeldgaard, M., Improved methods for building protein models in electron-density maps and the location of errors in these models (1991) Acta Crystallog. Sect. a, 47, pp. 110-119
Kraulis, P.J., MOLSCRIPT: A program to produce both detailed and schematic plots of protein structures (1991) J. Appl. Crystallog., 24, pp. 946-950
Laskowskoi, R.A., MacArthur, M.W., Moss, D.S., Thornton, J.M., PROCHECK: A program to check for stereochemical quality of protein structures (1993) J. Appl. Crystallog., 26, pp. 283-291
Leslie, A.G.W., Recent changes to the MOSFLM package for processing film and image plate data (1992) CCP4 and ESF-EACMB Newsletter on Protein Crystallography No.26, , Warrington: SERCDaresbury Laboratory
Merrit, E., Murphy, M., RASTER3D version 2.0: A program for photorealistic molecular graphics (1994) Acta Crystallog. Sect. D, 50, pp. 869-879
Mylvaganam, S.E., Bonaventura, C., Bonaventura, J., Getzoff, E.D., Structural basis for the Root effect in haemoglobin (1996) Nature Struct. Biol., 3, pp. 275-283
Perutz, M.F., Cause of the Root effect in fish haemoglobin (1996) Nature Struct. Biol., 3, pp. 211-212
Perutz, M.F., Brunori, M., Stereochemistry of cooperative effects in fish and amphibian haemoglobins (1982) Nature, 299, pp. 421-426
Perutz, M.F., Fermi, G., Luisi, B., Shaanan, B., Liddington, R., Stereochemistry of cooperative mechanism in hemoglobin (1987) Acc. Chem. Res., 20, pp. 309-321
Shih, D.T., Luisi, B.F., Miyazaky, G., Perutz, M.F., Nagai, K., A mutagenic study of the allosteric linkage of His(HC3)146 β in haemoglobin (1993) J. Mol. Biol., 230, pp. 1291-1296
Tame, J.R.H., Wilson, J.C., Weber, R.E., The crystal structures of Trout Hb I in the deoxy and carbonmonoxy forms (1996) J. Mol. Biol., 259, pp. 749-760
Weber, R.E., Jessen, T.-H., Malte, H., Tame, J., Mutant hemoglobins (α119-Ala and β55-Ser): Functions related to high altitude respiration in geese (1993) J. Appl. Physiol., 75, pp. 2646-2655
Zhang, J., Hua, Z., Tame, J.R.H., Zhang, G.L.R., Gu, X., The crystal structure of a high oxygen affinity species of haemoglobin (1996) J. Mol. Biol., 255, pp. 484-493
Baldwin, J. M., Chothia, C., Haemoglobin: The structural changes related to ligand binding and its allosteric mechanism (1979) J. Mol. Biol., 129, pp. 175-22
Br nger, A. T., (1992) X-PLOR Manual, Version 3. 1, , New Haven: Yale University Press
Derewenda, Z. D., Dodson, G. G., Emsley, P., Harris, D., Nagai, K., Perutz, M. F., Reynard, J. -P., Stereochemistry of carbon monoxide binding to normal human adult and Cowtown haemoglobin (1990) J. Mol. Biol., 211, pp. 515-519
Hendrikson, W. A., Stereochemically restrained refinement of macromolecular structures (1985) Methods Enzymol., 115, pp. 252-270
Jones, T. A., Interactive computer graphics: FRODO (1985) Methods. Enzymol., 115, pp. 157-171
Jones, T. A., Zou, J. -Y., Cowan, S. W., Kjeldgaard, M., Improved methods for building protein models in electron-density maps and the location of errors in these models (1991) Acta Crystallog. Sect. a, 47, pp. 110-119
Kraulis, P. J., MOLSCRIPT: A program to produce both detailed and schematic plots of protein structures (1991) J. Appl. Crystallog., 24, pp. 946-950
Laskowskoi, R. A., MacArthur, M. W., Moss, D. S., Thornton, J. M., PROCHECK: A program to check for stereochemical quality of protein structures (1993) J. Appl. Crystallog., 26, pp. 283-291
Leslie, A. G. W., Recent changes to the MOSFLM package for processing film and image plate data (1992) CCP4 and ESF-EACMB Newsletter on Protein Crystallography No. 26, , Warrington: SERCDaresbury Laboratory
Mylvaganam, S. E., Bonaventura, C., Bonaventura, J., Getzoff, E. D., Structural basis for the Root effect in haemoglobin (1996) Nature Struct. Biol., 3, pp. 275-283
Perutz, M. F., Cause of the Root effect in fish haemoglobin (1996) Nature Struct. Biol., 3, pp. 211-212
Perutz, M. F., Brunori, M., Stereochemistry of cooperative effects in fish and amphibian haemoglobins (1982) Nature, 299, pp. 421-426
Perutz, M. F., Fermi, G., Luisi, B., Shaanan, B., Liddington, R., Stereochemistry of cooperative mechanism in hemoglobin (1987) Acc. Chem. Res., 20, pp. 309-321
Shih, D. T., Luisi, B. F., Miyazaky, G., Perutz, M. F., Nagai, K., A mutagenic study of the allosteric linkage of His (HC3) 146 in haemoglobin (1993) J. Mol. Biol., 230, pp. 1291-1296
Tame, J. R. H., Wilson, J. C., Weber, R. E., The crystal structures of Trout Hb I in the deoxy and carbonmonoxy forms (1996) J. Mol. Biol., 259, pp. 749-760
Weber, R. E., Jessen, T. -H., Malte, H., Tame, J., Mutant hemoglobins (119-Ala and 55-Ser): Functions related to high altitude respiration in geese (1993) J. Appl. Physiol., 75, pp. 2646-2655
Crystal structure of Trematomus newnesi haemoglobin re-opens the Root effect question
As new structural data have become available, somewhat contrasting explanations of the Root effect in fish haemoglobins (Hb) have been provided. Hb 1 of the Antarctic fish Trematomus newnesi has a nearly pH-independent oxygen affinity, in spite of 95 % sequence identity with Hb 1 of Trematomus (previously named Pagothenia) bernacchii that has a strong Root effect. Here, the 2.2 Angstrom R-state structure of Trematomus newnesi Ho 1 is presented. The structure is similar to that of Root effect fish Kbs from Spot and T. bernacchii, suggesting that the differences in the pH dependence cannot be related to the modulation of the R-state. In comparison to T, bernacchii Hb 1, the role of the three mutations Thr41 (C6)alpha --> Ile, Ala97 (G3)alpha --> Ser and His41 (C7)beta --> Tyr at the alpha(1)beta(2)-interface is discussed. (C) 1999 Academic Press.
As new structural data have become available, somewhat contrasting explanations of the Root effect in fish haemoglobins (Hb) have been provided. Hb 1 of the Antarctic fish Trematomus newnesi has a nearly pH-independent oxygen affinity, in spite of 95 % sequence identity with Hb 1 of Trematomus (previously named Pagothenia) bernacchii that has a strong Root effect. Here, the 2.2 Angstrom R-state structure of Trematomus newnesi Ho 1 is presented. The structure is similar to that of Root effect fish Kbs from Spot and T. bernacchii, suggesting that the differences in the pH dependence cannot be related to the modulation of the R-state. In comparison to T, bernacchii Hb 1, the role of the three mutations Thr41 (C6)alpha --> Ile, Ala97 (G3)alpha --> Ser and His41 (C7)beta --> Tyr at the alpha(1)beta(2)-interface is discussed. (C) 1999 Academic Press.
Crystal structure of Trematomus newnesi haemoglobin re-opens the Root effect question
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Crystal structure of Trematomus newnesi haemoglobin re-opens the Root effect question
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Diana D, Basile A, De Rosa L, Di Stasi R, Auriemma S, Arra C, Pedone C, Turco MC, Fattorusso R, D'Andrea LD
* Beta-Hairpin Peptide That Targets Vascular Endothelial Growth Factor (vegf) Receptors: Design, Nmr Characterization, And Biological Activity (620 views)
Jbc Papers (ISSN: 1083-351x, 0021-9258, 0021-9258linking), 2011 Dec 2; 286(48): 41680-41691.
Impact Factor: 4.773
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Merlino A, Howes BD, Prisco G, Verde C, Smulevich G, Mazzarella L, Vergara A
* Occurrence and formation of endogenous histidine hexa-coordination in cold-adapted hemoglobins (410 views)
Iubmb Life (ISSN: 1521-6543, 1521-6551), 2011 May; 63(5): 295-303.
Impact Factor: 3.514
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Boechi L, Marti MA, Vergara A, Sica F, Mazzarella L, Estrin DA, Merlino A
* Protonation of Histidine 55 Affects the Oxygen Access to Heme in the Alpha Chain of the Hemoglobin from the Antarctic Fish Trematomus bernacchii (370 views)
Iubmb Life (ISSN: 1521-6543, 1521-6551), 2011 Mar; 63(3): 175-182.
Impact Factor: 3.514
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Merlino A, Vitagliano L, Balsamo A, Nicoletti FP, Howes BD, Giordano D, Coppola D, Di Prisco G, Verde C, Smulevich G, Mazzarella L, Vergara A
* Crystallization, preliminary X-ray diffraction studies and Raman microscopy of the major haemoglobin from the sub-Antarctic fish Eleginops maclovinus in the carbomonoxy form (317 views)
Nucleosides Nucleotides Nucleic Acids (ISSN: 1744-3091, 1744-4309), 2010 Nov; 66: 1536-1540.
Impact Factor: 0.563
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Vergara A, Vitagliano L, Merlino A, Sica F, Marino K, Verde C, di Prisco G, Mazzarella L
* An Order-Disorder Transition Plays a Role in Switching Off the Root Effect in Fish Hemoglobins (363 views)
Jbc Papers (ISSN: 0021-9258, 1083-351x, 0021-9258linking), 2010 Oct 15; 285(42): 32568-32575.
Impact Factor: 5.328
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Coppola D, Giordano D, Vergara A, Mazzarella L, Di Prisco G, Verde C, Russo R
* The hemoglobins of sub-Antarctic fishes of the suborder Notothenioidei (434 views)
Polar Science (ISSN: 1873-9652), 2010 Sep; 4(2): 295-308.
Impact Factor: 31.477
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Merlino A, Vergara A, Sica F, Aschi M, Amadei A, Di Nola A, Mazzarella L
* Free-Energy Profile for CO Binding to Separated Chains of Human and Trematomus newnesi Hemoglobin: Insights from Molecular Dynamics Simulations and Perturbed Matrix Method (301 views)
J Phys Chem B (ISSN: 1520-6106, 1520-5207, 1520-5207electronic), 2010 May 27; 114(20): 7002-7008.
Impact Factor: 3.603
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Merlino A, Vitagliano L, Howes BD, Verde C, Di Prisco G, Smulevich G, Sica F, Vergara A
* Combined Crystallographic and Spectroscopic Analysis of Trematomus bernacchii Hemoglobin Highlights Analogies and Differences in the Peculiar Oxidation Pathway of Antarctic Fish Hemoglobins (416 views)
Biopolymers (ISSN: 0006-3525, 0006-6352, 0006-3525print), 2009 Dec; 91(12): 1117-1125.
Impact Factor: 2.605
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Puglisi A, Rizzarelli E, Vecchio G, Iacovino R, Benedetti E, Pedone C, Saviano M
* Crystal And Molecular Structure Of Beta-Cyclodextrins Functionalized With The Anti-Inflammatory Drug Etodolac (420 views)
Biopolymers (ISSN: 0006-3525, 0006-6352, 0006-3525print), 2009 Dec; 91(12): 1227-1235.
Impact Factor: 2.605
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Vergara A, Franzese M, Merlino A, Bonomi G, Verde C, Giordano D, Di Prisco G, Lee HC, Peisach J, Mazzarella L
* Correlation between Hemichrome Stability and the Root Effect in Tetrameric Hemoglobins (407 views)
Biophysical Journal (ISSN: 0006-3495, 1542-0086), 2009 Sep 5; 97(3): 866-874.
Impact Factor: 4.39
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Giordano D, Boechi L, Vergara A, Marti MA, Samuni U, Dantsker D, Grassi L, Estrin DA, Friedman JM, Mazzarella L, Di Prisco G, Verde C
* The hemoglobins of the sub-Antarctic fish Cottoperca gobio, a phyletically basal species - oxygen-binding equilibria, kinetics and molecular dynamics (709 views)
Febs Journal (ISSN: 1742-464x), 2009 Apr; 276(8): 2266-2277.
Impact Factor: 3.042
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Merlino A, Vergara A, Sica F, Mazzarella L
* The bis-histidyl complex in hemoproteins: A detailed conformational analysis of database protein structures and the case of Antarctic fish hemoglobins (334 views)
Marine Genomics (ISSN: 1874-7787), 2009 Mar; 2(1): 51-56.
Impact Factor: 1.2
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Verde C, Vergara A, Mazzarella L, Di Prisco G
* The Hemoglobins of Fishes Living at Polar Latitudes - Current Knowledge on Structural Adaptations in a Changing Environment (389 views)
Curr Protein Pept Sci (ISSN: 1389-2037, 1389-2037linking), 2008 Dec; 9(6): 578-590.
Impact Factor: 3.011
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Esposito L, Seydel A, Aiello R, Sorrentino G, Cendron L, Zanotti G, Zagari
* The crystal structure of the superoxide dismutase from Helicobacter pylori reveals a structured C-terminal extension (425 views)
Bba-Gen Subjects (ISSN: 1570-9639, 0006-3002, 0925-4439), 2008 Nov; 1784(11): 1601-1606.
Impact Factor: 2.233
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Cigliano L, Maresca B, Salvatore A, Nino M, Monfrecola G, Ayala F, Carlucci A, Pugliese RC, Pedone C, Abrescia P
* Haptoglobin from psoriatic patients exhibits decreased activity in binding haemoglobin and inhibiting lecithin-cholesterol acyltransferase activity (417 views)
Journal Of The European Academy Of Dermatology And Venereology (ISSN: 1468-3083, 0926-9959), 2008 Apr; 22(4): 417-425.
Impact Factor: 2.276
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D'Ambrosio K, Masereel B, Thiry A, Scozzafava A, Supuran CT, De Simone G
* Carbonic anhydrase inhibitors: Binding of indanesulfonamides to the human isoform II (378 views)
Chemmedchem (ISSN: 1860-7179, 1860-7187, 1860-7187electronic), 2008 Mar; 3(3): 473-477.
Impact Factor: 3.15
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Vergara A, Verde C, Di Prisco G, Mazzarella L
* Bis-histidyl Ferric Adducts in Tetrameric Haemoglobins (187 views)
Protein Reviews, 2008; 9: N/D-N/D.
Impact Factor: 0
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Merlino A, Verde C, Di Prisco G, Mazzarella L, Vergara A
* Reduction of ferric hemoglobin from Trematomus bernacchii in a partial bis-histidyl state produces a deoxy coordination even when encapsulated into the crystal phase (414 views)
Spectroscopy An International Journal (ISSN: 0712-4813), 2008; 22(2-3): 143-152.
Impact Factor: 0.82
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Vergara A, Franzese M, Merlino A, Vitagliano L, Verde C, Di Prisco G, Lee HC, Peisach J, Mazzarella L
* Structural characterization of ferric hemoglobins from three Antarctic fish species of the suborder notothenioidei (375 views)
Biophysical Journal (ISSN: 0006-3495, 1542-0086), 2007 Oct; 93(8): 2822-2829.
Impact Factor: 4.627
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Verde C, Vergara A, Giordano D, Mazzarella L, Di Prisco G
* The Root effect - a structural and evolutionary perspective (251 views)
Antarctic Science (ISSN: 0954-1020), 2007 Jun; 19(2): 271-278.
Impact Factor: 1.265
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Merlino A, Sica F, Mazzarella L
* Approximate values for force constant and wave number associated with a low-frequency concerted motion in proteins can be evaluated by a comparison of X-ray structures (214 views)
J Phys Chem B (ISSN: 1520-6106, 1520-5207, 1520-5207electronic), 2007 May 17; 111(19): 5483-5486.
Impact Factor: 4.086
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Pailot A, D'Ambrosio K, Corbier C, Talfournier F, Branlant G
* Invariant Thr(244) is essential for the efficient acylation step of the non-phosphorylating glyceraldehyde-3-phosphate dehydrogenase from Streptococcus mutans (338 views)
Biochem J (ISSN: 0264-6021, 1470-8728electronic, 0264-6021linking), 2006 Dec 15; 400: 521-530.
Impact Factor: 4.1
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Mazzarella L, Vergara A, Vitagliano L, Merlino A, Bonomi G, Scala S, Verde C, Di Prisco G
* High resolution crystal structure of deoxy hemoglobin from Trematomus bernacchii at different pH values: The role of histidine residues in modulating the strength of the root effect (402 views)
Proteins (ISSN: 0887-3585, 1097-0134, 1097-0134electronic), 2006 Nov 1; 65(2): 490-498.
Impact Factor: 3.73
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Mazzarella L, Bonomi G, Lubrano MC, Merlino A, Riccio A, Vergara A, Vitagliano L, Verde C, Di Prisco G
* Minimal structural requirements for root effect: Crystal structure of the cathodic hemoglobin isolated from the Antarctic fish Trematomus newnesi (507 views)
Proteins (ISSN: 0887-3585, 1097-0134, 1097-0134electronic), 2006 Feb 1; 62(2): 316-321.
Impact Factor: 3.73
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Merlino A, Mazzarella L, Carannante A, Di Fiore A, Di Donato A, Notomista E, Sica F
* The importance of dynamic effects on the enzyme activity: X-ray structure and molecular dynamics of onconase mutants (442 views)
Jbc Papers (ISSN: 0021-9258, 1083-351x, 0021-9258linking), 2005 May 6; 280(18): 17953-17960.
Impact Factor: 5.854
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Vitagliano L, Bonomi G, Franzese M, Merlino A, Vergara A, Verde C, Di Prisco G, Mazzarella L
* Structural Characterization Of The Oxidation Pathway Of Antarctic Fish Hemoglobins (313 views)
Acta Crystallogr D Biol Crystallogr, 2005; N/D: N/D-N/D.
Impact Factor: 2.069
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Vitagliano L, Bonomi G, Riccio A, di Prisco G, Smulevich G, Mazzarella L
* The oxidation process of Antarctic fish hemoglobins (454 views)
Eur J Biochem (ISSN: 0014-2956, 0014-2956print), 2004 May; 271(9): 1651-1659.
Impact Factor: 3.26
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Riccio A, Vitagliano L, Di Prisco G, Zagari A, Mazzarella L
* The crystal structure of a tetrameric hemoglobin in a partial hemichrome state (553 views)
P Natl Acad Sci Usa (ISSN: 0027-8424, 1091-6490, 0027-8424print), 2002 Jul 23; 99(15): 9801-9806.
Impact Factor: 10.7
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Berisio R, Vitagliano L, Mazzarella L, Zagari A
* Crystal structure of the collagen triple helix model [(Pro-Pro-Gly)10]3 (660 views)
Protein Sci (ISSN: 0961-8368, 1469-896xelectronic), 2002 Feb; 11(2): 262-270.
Impact Factor: 3.546
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Menchise V, Corbier C, Didierjean C, Saviano M, Benedetti E, Jacquot JP, Aubry A
* Crystal structure of the wild-type and D30A mutant thioredoxin h of Chlamydomonas reinhardtii and implications for the catalytic mechanism (454 views)
Biochem J (ISSN: 0264-6021, 1470-8728electronic, 0264-6021linking), 2001 Oct 1; 359(1): 65-75.
Impact Factor: 4.326
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Riccio A, Vitagliano L, Di Prisco G, Zagari A, Mazzarella L
* Liganded and unliganded forms of Antarctic fish haemoglobins in polyethylene glycol: crystallization of an R-state haemichrome intermediate (401 views)
Acta Crystallogr D Biol Crystallogr (ISSN: 0907-4449, 0907-4449linking), 2001 Sep; 57: 1144-1146.
Impact Factor: 2.124
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Romanelli A, Garella I, Menchise V, Iacovino R, Saviano M, Montesarchio D, Didierjean C, Lello PD, Rossi F, Benedetti E
* Crystal-state conformation of Cα, α-dialkylated peptides containing chiral β-homo-residues (519 views)
J Pept Sci (ISSN: 1075-2617, 1099-1387, 1075-2617print), 2001; 7(1): 15-26.
Impact Factor: 1.451
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Vitagliano L, Merlino A, Zagari A, Mazzarella L
Productive and nonproductive binding to ribonuclease A: X-ray structure of two complexes with uridylyl(2 ', 5 ')guanosine (680 views)
Protein Sci (ISSN: 0961-8368, 1469-896xelectronic), 2000 Jun; 9(6): 1217-1225.
Impact Factor: 3.869
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Berisio R, Vitagliano L, Mazzarella L, Zagari A
Crystal Structure Of A Collagen-Like Polypeptide With Repeating Sequence Pro-Hyp-Gly At 1. 4 Ang Resolution: Implications For Collagen Hydration (441 views)
Biopolymers (ISSN: 0006-3525, 0006-6352, 0006-3525print), 2000; 56(1): 8-13.
Impact Factor: 2.405
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Vitagliano L, Adinolfi S, Riccio A, Sica F, Zagari A, Mazzarella L
Binding of a substrate analog to a domain swapping protein: X-ray structure of the complex of bovine seminal ribonuclease with uridylyl(2 ', 5 ')adenosine (465 views)
Protein Sci (ISSN: 0961-8368, 1469-896xelectronic), 1998 Sep; 7(8): 1691-1699.
Impact Factor: 4.44
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* The unique structural features of carbonmonoxy hemoglobin from the sub-Antarctic fish Eleginops maclovinus (176 views)
Sci Rep (ISSN: 2045-2322linking, 2045-2322electronic), 2019 Dec 12; 9(1): 18987-18987.
Impact Factor: 5.078
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Pontillo N, Ferraro G, Helliwell JR, Amoresano A, Merlino A
* X-ray Structure of the Carboplatin-Loaded Apo-Ferritin Nanocage (236 views)
Acs Med Chem Lett (ISSN: 1948-5875, 1948-5875linking), 2017 Feb 28; 8(4): 433-437.
Impact Factor: 3.794
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Tamasi G, Merlino A, Scaletti F, Heffeter P, Legin AA, Jakupec MA, Berger W, Messori L, Keppler BK, Cini R
* {Ru(CO)x}-Core complexes with benzimidazole ligands: synthesis, X-ray structure and evaluation of anticancer activity in vivo (313 views)
Dalton T (ISSN: 1477-9226, 1477-9234, 1477-9226linking), 2017 Feb 28; 46(9): 3025-3040.
Impact Factor: 4.099
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Langella E, D'Ambrosio K, D'Ascenzio M, Carradori S, Monti SM, Supuran CT, De Simone G
* A Combined Crystallographic and Theoretical Study Explains the Capability of Carboxylic Acids to Adopt Multiple Binding Modes in the Active Site of Carbonic Anhydrases (336 views)
Chemistry (ISSN: 0947-6539, 1521-3765, 1521-3765electronic), 2016 Jan 4; 22(1): 97-100.
Impact Factor: 5.317
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Messori L, Marzo T, Merlino A
* Interactions of carboplatin and oxaliplatin with proteins: Insights from X-ray structures and mass spectrometry studies of their ribonuclease A adducts (312 views)
J Chem Res (ISSN: 0162-0134, 1873-3344, 0162-0134print), 2015; N/D: N/D-N/D.
Impact Factor: 3.205
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Marasco D, Messori L, Marzo T, Merlino A
* Oxaliplatin vs. cisplatin: Competition experiments on their binding to lysozyme (724 views)
Dalton T (ISSN: 1477-9226, 1477-9234, 1477-9226linking), 2015; 44(22): 10392-10398.
Impact Factor: 4.177
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Ferraro G, Messori L, Merlino A
* The X-ray structure of the primary adducts formed in the reaction between cisplatin and cytochrome (323 views)
Chem Commun (ISSN: 1359-7345, 1364-548x, 1364-548xelectronic), 2015; 51(13): 2559-2561.
Impact Factor: 6.567
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Merlino A, Vergara A, Vitagliano L
* Comments on Structural studies of haemoglobin from pisces species shortfin mako shark (Isurus oxyrinchus) at 1. 9 angstrom resolution by P. Ramesh et al. (2013). J. Synchrotron Rad. 20, 843-847 (282 views)
J Synchrotron Radiat (ISSN: 0909-0495), 2014 Jul; 21: N/D-N/D.
Impact Factor: 2.794
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Lin L-L, Chen Y-Y, Chi M-C, Merlino A
* Low resolution X-ray structure of γ-glutamyltranspeptidase from Bacillus licheniformis: Opened active site cleft and a cluster of acid residues potentially involved in the recognition of a metal ion (696 views)
Bba-Gen Subjects (ISSN: 0925-4439, 0006-3002, 1570-9639), 2014; 1844(9): 1523-1529.
Impact Factor: 4.882
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Mazzarella L, Merlino A, Vitagliano L, Verde C, Di Prisco G, Peisach J, Vergara A
* Structural modifications induced by the switch from an endogenous bis-histidyl to an exogenous cyanomet hexa-coordination in a tetrameric haemoglobin (287 views)
Rsc Adv (ISSN: 2046-2069), 2014; 4(49): 25852-25856.
Impact Factor: 3.84
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Vergara A, Russo Krauss I, Montesarchio D, Paduano L, Merlino A
* Investigating the Ruthenium Metalation of Proteins: X-ray Structure and Raman Microspectroscopy of the Complex between RNase A and AziRu (309 views)
Inorg Chem (ISSN: 0020-1669, 1520-510x, 1520-510xelectronic), 2013 Oct 7; 52(19): 10714-10716.
Impact Factor: 4.794
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Pica A, Merlino A, Buell AK, Knowles TJ, Pizzo E, D'Alessio G, Sica F, Mazzarella L
* Three-dimensional domain swapping and supramolecular protein assembly: insights from the X-ray structure of a dimeric swapped variant of human pancreatic RNase (1023 views)
Acta Crystallogr D Biol Crystallogr (ISSN: 0907-4449, 0907-4449linking), 2013 Oct; 69: 2116-2123.
Impact Factor: 7.232
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Ronda L, Merlino A, Bettati S, Verde C, Balsamo A, Mazzarella L, Mozzarelli A, Vergara A
* Role of tertiary structures on the Root effect in fish hemoglobins (544 views)
Bba-Gen Subjects (ISSN: 1570-9639, 0006-3002, 0925-4439), 2013 Sep; 1834(9): 1885-1893.
Impact Factor: 3.191
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Di Fiore A, Capasso C, De Luca V, Monti SM, Carginale V, Supuran CT, Scozzafava A, Pedone C, Rossi M, De Simone G
* X-ray structure of the first 'extremo-alpha-carbonic anhydrase', a dimeric enzyme from the thermophilic bacterium Sulfurihydrogenibium yellowstonense YO3AOP1 (670 views)
Acta Crystallogr D Biol Crystallogr (ISSN: 0907-4449, 0907-4449linking), 2013 Jun; 69(6): 1150-1159.
Impact Factor: 7.232
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Vergara A, D’Errico G, Montesarchio D, Mangiapia G, Paduano L, Merlino A
* Interaction of Anticancer Ruthenium Compounds with Proteins: High-Resolution X-ray Structures and Raman Microscopy Studies of the Adduct between Hen Egg White Lysozyme and AziRu (352 views)
Inorg Chem (ISSN: 0020-1669, 1520-510x, 1520-510xelectronic), 2013 Apr 15; 52(8): 4157-4159.
Impact Factor: 4.794
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Merlino A, Fuchs MR, Pica A, Balsamo A, Dworkowski FSN, Pompidor G, Mazzarella L, Vergara A
* Selective X-ray-induced NO photodissociation in haemoglobin crystals: evidence from a Raman-assisted crystallographic study (339 views)
Acta Crystallogr D Biol Crystallogr (ISSN: 0907-4449, 0907-4449linking), 2013 Jan; 69: 137-140.
Impact Factor: 7.232
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Vergara A, Montesarchio D, Russo Krauss I, Paduano L, Merlino A
* Investigating The Ruthenium Metallation Of Proteins: X-Ray Structure And Raman Microspectroscopy Of The Complex Between Rnase A And Aziru (293 views)
Inorg Chem (ISSN: 0020-1669, 1520-510xe, 1520-510xelectronic), 2013; 52(19): 10714-10716.
Impact Factor: 4.794
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Coppola D, Abbruzzetti S, Nicoletti F, Merlino A, Gambacurta A, Giordano D, Howes BD, De Sanctis G, Vitagliano L, Bruno S, di Prisco G, Mazzarella L, Smulevich G, Coletta M, Viappiani C, Vergara A, Verde C
* ATP regulation of the ligand-binding properties in temperate and cold-adapted haemoglobins. X-ray structure and ligand-binding kinetics in the sub-Antarctic fish Eleginops maclovinus (343 views)
Molecular Biosystems (ISSN: 1742-206x), 2012 Oct 30; 8(12): 3295-3304.
Impact Factor: 3.35
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Risitano AM, Imbriaco M, Marando L, Seneca E, Soscia E, Malcovati L, Iori AP, Pane F, Notaro R, Matarazzo M
* From perpetual haemosiderinuria to possible iron overload: iron redistribution in paroxysmal nocturnal haemoglobinuria patients on eculizumab by magnetic resonance imaging (360 views)
Br J Haematol (ISSN: 0007-1048, 0007-1048linking, 1365-2141electronic), 2012 Sep; 158(3): 415-418.
Impact Factor: 4.942
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Diana D, Basile A, De Rosa L, Di Stasi R, Auriemma S, Arra C, Pedone C, Turco MC, Fattorusso R, D'Andrea LD
* Beta-Hairpin Peptide That Targets Vascular Endothelial Growth Factor (vegf) Receptors: Design, Nmr Characterization, And Biological Activity (620 views)
Jbc Papers (ISSN: 1083-351x, 0021-9258, 0021-9258linking), 2011 Dec 2; 286(48): 41680-41691.
Impact Factor: 4.773
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Merlino A, Howes BD, Prisco G, Verde C, Smulevich G, Mazzarella L, Vergara A
* Occurrence and formation of endogenous histidine hexa-coordination in cold-adapted hemoglobins (410 views)
Iubmb Life (ISSN: 1521-6543, 1521-6551), 2011 May; 63(5): 295-303.
Impact Factor: 3.514
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Boechi L, Marti MA, Vergara A, Sica F, Mazzarella L, Estrin DA, Merlino A
* Protonation of Histidine 55 Affects the Oxygen Access to Heme in the Alpha Chain of the Hemoglobin from the Antarctic Fish Trematomus bernacchii (370 views)
Iubmb Life (ISSN: 1521-6543, 1521-6551), 2011 Mar; 63(3): 175-182.
Impact Factor: 3.514
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Merlino A, Vitagliano L, Balsamo A, Nicoletti FP, Howes BD, Giordano D, Coppola D, Di Prisco G, Verde C, Smulevich G, Mazzarella L, Vergara A
* Crystallization, preliminary X-ray diffraction studies and Raman microscopy of the major haemoglobin from the sub-Antarctic fish Eleginops maclovinus in the carbomonoxy form (317 views)
Nucleosides Nucleotides Nucleic Acids (ISSN: 1744-3091, 1744-4309), 2010 Nov; 66: 1536-1540.
Impact Factor: 0.563
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Vergara A, Vitagliano L, Merlino A, Sica F, Marino K, Verde C, di Prisco G, Mazzarella L
* An Order-Disorder Transition Plays a Role in Switching Off the Root Effect in Fish Hemoglobins (363 views)
Jbc Papers (ISSN: 0021-9258, 1083-351x, 0021-9258linking), 2010 Oct 15; 285(42): 32568-32575.
Impact Factor: 5.328
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Coppola D, Giordano D, Vergara A, Mazzarella L, Di Prisco G, Verde C, Russo R
* The hemoglobins of sub-Antarctic fishes of the suborder Notothenioidei (434 views)
Polar Science (ISSN: 1873-9652), 2010 Sep; 4(2): 295-308.
Impact Factor: 31.477
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Merlino A, Vergara A, Sica F, Aschi M, Amadei A, Di Nola A, Mazzarella L
* Free-Energy Profile for CO Binding to Separated Chains of Human and Trematomus newnesi Hemoglobin: Insights from Molecular Dynamics Simulations and Perturbed Matrix Method (301 views)
J Phys Chem B (ISSN: 1520-6106, 1520-5207, 1520-5207electronic), 2010 May 27; 114(20): 7002-7008.
Impact Factor: 3.603
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Merlino A, Vitagliano L, Howes BD, Verde C, Di Prisco G, Smulevich G, Sica F, Vergara A
* Combined Crystallographic and Spectroscopic Analysis of Trematomus bernacchii Hemoglobin Highlights Analogies and Differences in the Peculiar Oxidation Pathway of Antarctic Fish Hemoglobins (416 views)
Biopolymers (ISSN: 0006-3525, 0006-6352, 0006-3525print), 2009 Dec; 91(12): 1117-1125.
Impact Factor: 2.605
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Puglisi A, Rizzarelli E, Vecchio G, Iacovino R, Benedetti E, Pedone C, Saviano M
* Crystal And Molecular Structure Of Beta-Cyclodextrins Functionalized With The Anti-Inflammatory Drug Etodolac (420 views)
Biopolymers (ISSN: 0006-3525, 0006-6352, 0006-3525print), 2009 Dec; 91(12): 1227-1235.
Impact Factor: 2.605
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Vergara A, Franzese M, Merlino A, Bonomi G, Verde C, Giordano D, Di Prisco G, Lee HC, Peisach J, Mazzarella L
* Correlation between Hemichrome Stability and the Root Effect in Tetrameric Hemoglobins (407 views)
Biophysical Journal (ISSN: 0006-3495, 1542-0086), 2009 Sep 5; 97(3): 866-874.
Impact Factor: 4.39
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Giordano D, Boechi L, Vergara A, Marti MA, Samuni U, Dantsker D, Grassi L, Estrin DA, Friedman JM, Mazzarella L, Di Prisco G, Verde C
* The hemoglobins of the sub-Antarctic fish Cottoperca gobio, a phyletically basal species - oxygen-binding equilibria, kinetics and molecular dynamics (709 views)
Febs Journal (ISSN: 1742-464x), 2009 Apr; 276(8): 2266-2277.
Impact Factor: 3.042
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Merlino A, Vergara A, Sica F, Mazzarella L
* The bis-histidyl complex in hemoproteins: A detailed conformational analysis of database protein structures and the case of Antarctic fish hemoglobins (334 views)
Marine Genomics (ISSN: 1874-7787), 2009 Mar; 2(1): 51-56.
Impact Factor: 1.2
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Verde C, Vergara A, Mazzarella L, Di Prisco G
* The Hemoglobins of Fishes Living at Polar Latitudes - Current Knowledge on Structural Adaptations in a Changing Environment (389 views)
Curr Protein Pept Sci (ISSN: 1389-2037, 1389-2037linking), 2008 Dec; 9(6): 578-590.
Impact Factor: 3.011
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Esposito L, Seydel A, Aiello R, Sorrentino G, Cendron L, Zanotti G, Zagari
* The crystal structure of the superoxide dismutase from Helicobacter pylori reveals a structured C-terminal extension (425 views)
Bba-Gen Subjects (ISSN: 1570-9639, 0006-3002, 0925-4439), 2008 Nov; 1784(11): 1601-1606.
Impact Factor: 2.233
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Cigliano L, Maresca B, Salvatore A, Nino M, Monfrecola G, Ayala F, Carlucci A, Pugliese RC, Pedone C, Abrescia P
* Haptoglobin from psoriatic patients exhibits decreased activity in binding haemoglobin and inhibiting lecithin-cholesterol acyltransferase activity (417 views)
Journal Of The European Academy Of Dermatology And Venereology (ISSN: 1468-3083, 0926-9959), 2008 Apr; 22(4): 417-425.
Impact Factor: 2.276
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D'Ambrosio K, Masereel B, Thiry A, Scozzafava A, Supuran CT, De Simone G
* Carbonic anhydrase inhibitors: Binding of indanesulfonamides to the human isoform II (378 views)
Chemmedchem (ISSN: 1860-7179, 1860-7187, 1860-7187electronic), 2008 Mar; 3(3): 473-477.
Impact Factor: 3.15
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Vergara A, Verde C, Di Prisco G, Mazzarella L
* Bis-histidyl Ferric Adducts in Tetrameric Haemoglobins (187 views)
Protein Reviews, 2008; 9: N/D-N/D.
Impact Factor: 0
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Merlino A, Verde C, Di Prisco G, Mazzarella L, Vergara A
* Reduction of ferric hemoglobin from Trematomus bernacchii in a partial bis-histidyl state produces a deoxy coordination even when encapsulated into the crystal phase (414 views)
Spectroscopy An International Journal (ISSN: 0712-4813), 2008; 22(2-3): 143-152.
Impact Factor: 0.82
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Vergara A, Franzese M, Merlino A, Vitagliano L, Verde C, Di Prisco G, Lee HC, Peisach J, Mazzarella L
* Structural characterization of ferric hemoglobins from three Antarctic fish species of the suborder notothenioidei (375 views)
Biophysical Journal (ISSN: 0006-3495, 1542-0086), 2007 Oct; 93(8): 2822-2829.
Impact Factor: 4.627
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Verde C, Vergara A, Giordano D, Mazzarella L, Di Prisco G
* The Root effect - a structural and evolutionary perspective (251 views)
Antarctic Science (ISSN: 0954-1020), 2007 Jun; 19(2): 271-278.
Impact Factor: 1.265
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Merlino A, Sica F, Mazzarella L
* Approximate values for force constant and wave number associated with a low-frequency concerted motion in proteins can be evaluated by a comparison of X-ray structures (214 views)
J Phys Chem B (ISSN: 1520-6106, 1520-5207, 1520-5207electronic), 2007 May 17; 111(19): 5483-5486.
Impact Factor: 4.086
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Pailot A, D'Ambrosio K, Corbier C, Talfournier F, Branlant G
* Invariant Thr(244) is essential for the efficient acylation step of the non-phosphorylating glyceraldehyde-3-phosphate dehydrogenase from Streptococcus mutans (338 views)
Biochem J (ISSN: 0264-6021, 1470-8728electronic, 0264-6021linking), 2006 Dec 15; 400: 521-530.
Impact Factor: 4.1
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Mazzarella L, Vergara A, Vitagliano L, Merlino A, Bonomi G, Scala S, Verde C, Di Prisco G
* High resolution crystal structure of deoxy hemoglobin from Trematomus bernacchii at different pH values: The role of histidine residues in modulating the strength of the root effect (402 views)
Proteins (ISSN: 0887-3585, 1097-0134, 1097-0134electronic), 2006 Nov 1; 65(2): 490-498.
Impact Factor: 3.73
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Mazzarella L, Bonomi G, Lubrano MC, Merlino A, Riccio A, Vergara A, Vitagliano L, Verde C, Di Prisco G
* Minimal structural requirements for root effect: Crystal structure of the cathodic hemoglobin isolated from the Antarctic fish Trematomus newnesi (507 views)
Proteins (ISSN: 0887-3585, 1097-0134, 1097-0134electronic), 2006 Feb 1; 62(2): 316-321.
Impact Factor: 3.73
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Merlino A, Mazzarella L, Carannante A, Di Fiore A, Di Donato A, Notomista E, Sica F
* The importance of dynamic effects on the enzyme activity: X-ray structure and molecular dynamics of onconase mutants (442 views)
Jbc Papers (ISSN: 0021-9258, 1083-351x, 0021-9258linking), 2005 May 6; 280(18): 17953-17960.
Impact Factor: 5.854
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Vitagliano L, Bonomi G, Franzese M, Merlino A, Vergara A, Verde C, Di Prisco G, Mazzarella L
* Structural Characterization Of The Oxidation Pathway Of Antarctic Fish Hemoglobins (313 views)
Acta Crystallogr D Biol Crystallogr, 2005; N/D: N/D-N/D.
Impact Factor: 2.069
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Vitagliano L, Bonomi G, Riccio A, di Prisco G, Smulevich G, Mazzarella L
* The oxidation process of Antarctic fish hemoglobins (454 views)
Eur J Biochem (ISSN: 0014-2956, 0014-2956print), 2004 May; 271(9): 1651-1659.
Impact Factor: 3.26
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Riccio A, Vitagliano L, Di Prisco G, Zagari A, Mazzarella L
* The crystal structure of a tetrameric hemoglobin in a partial hemichrome state (553 views)
P Natl Acad Sci Usa (ISSN: 0027-8424, 1091-6490, 0027-8424print), 2002 Jul 23; 99(15): 9801-9806.
Impact Factor: 10.7
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Berisio R, Vitagliano L, Mazzarella L, Zagari A
* Crystal structure of the collagen triple helix model [(Pro-Pro-Gly)10]3 (660 views)
Protein Sci (ISSN: 0961-8368, 1469-896xelectronic), 2002 Feb; 11(2): 262-270.
Impact Factor: 3.546
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Menchise V, Corbier C, Didierjean C, Saviano M, Benedetti E, Jacquot JP, Aubry A
* Crystal structure of the wild-type and D30A mutant thioredoxin h of Chlamydomonas reinhardtii and implications for the catalytic mechanism (454 views)
Biochem J (ISSN: 0264-6021, 1470-8728electronic, 0264-6021linking), 2001 Oct 1; 359(1): 65-75.
Impact Factor: 4.326
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Riccio A, Vitagliano L, Di Prisco G, Zagari A, Mazzarella L
* Liganded and unliganded forms of Antarctic fish haemoglobins in polyethylene glycol: crystallization of an R-state haemichrome intermediate (401 views)
Acta Crystallogr D Biol Crystallogr (ISSN: 0907-4449, 0907-4449linking), 2001 Sep; 57: 1144-1146.
Impact Factor: 2.124
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Romanelli A, Garella I, Menchise V, Iacovino R, Saviano M, Montesarchio D, Didierjean C, Lello PD, Rossi F, Benedetti E
* Crystal-state conformation of Cα, α-dialkylated peptides containing chiral β-homo-residues (519 views)
J Pept Sci (ISSN: 1075-2617, 1099-1387, 1075-2617print), 2001; 7(1): 15-26.
Impact Factor: 1.451
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Vitagliano L, Merlino A, Zagari A, Mazzarella L
Productive and nonproductive binding to ribonuclease A: X-ray structure of two complexes with uridylyl(2 ', 5 ')guanosine (680 views)
Protein Sci (ISSN: 0961-8368, 1469-896xelectronic), 2000 Jun; 9(6): 1217-1225.
Impact Factor: 3.869
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Berisio R, Vitagliano L, Mazzarella L, Zagari A
Crystal Structure Of A Collagen-Like Polypeptide With Repeating Sequence Pro-Hyp-Gly At 1. 4 Ang Resolution: Implications For Collagen Hydration (441 views)
Biopolymers (ISSN: 0006-3525, 0006-6352, 0006-3525print), 2000; 56(1): 8-13.
Impact Factor: 2.405
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Vitagliano L, Adinolfi S, Riccio A, Sica F, Zagari A, Mazzarella L
Binding of a substrate analog to a domain swapping protein: X-ray structure of the complex of bovine seminal ribonuclease with uridylyl(2 ', 5 ')adenosine (465 views)
Protein Sci (ISSN: 0961-8368, 1469-896xelectronic), 1998 Sep; 7(8): 1691-1699.
Impact Factor: 4.44
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54 Records (51 excluding Abstracts).
Total impact factor: 235 (230.137 excluding Abstracts).
Total 5 year impact factor: 268.587 (248.683 excluding Abstracts).
Total impact factor: 235 (230.137 excluding Abstracts).
Total 5 year impact factor: 268.587 (248.683 excluding Abstracts).
435 views. Last view on Friday 21 April 2023, 13:16:45
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