Nanoparticles exposing neurotensin tumor-specific drivers (448 views)
J Pept Sci (ISSN: 1075-2617, 1099-1387, 1075-2617print), 2013 Apr; 19(4): 198-204.
Export to BibTeX Export to EndNote
Paper type: Journal Article,
Impact factor: 1.862, 5-year impact factor: 1.715
Url: http://www.scopus.com/inward/record.url?eid=2-s2.0-84875632201&partnerID=40&md5=9fad6e962fe3d586545ed859cd400a62
Keywords: Branched Peptides, Doxorubicin, Liposome, Tumor-Targeting, Anthracycline, Linear Neurotensin Peptide Nt, Nanoparticle, Tetrabranched Neurotensin Peptide Nt4, Unclassified Drug, Cell Fusion, Cell Membrane, Controlled Study, Cytotoxicity, Drug Delivery System, Drug Protein Binding, Human, Human Cell, Internalization, Priority Journal, Target Cell, Tumor Cell, Antibiotics, Antineoplastic, Cell Line,
Affiliations:
*** IBB - CNR ***
Department of Medical Biotechnology, University of Siena, Via Fiorentina 1, Siena, 53100, Italy
Department of Pharmacy, Centro Interuniversitario di Ricerca sui Peptidi Bioattivi, University of Naples 'Federico II', Istituto di Biostrutture e Bioimmagin, CNR, Via Mezzocannone 16, Naples, 80134, Italy
Istituto Toscano Tumori, Siena, Italy
References:
Ohanian, M., Cortes, J., Kantarjian, H., Jabbour, E., Tyrosine kinase inhibitors in acute and chronic leukemias (2012) Expert Opin. Pharmacother., 13 (7), pp. 927-93
Markman, B., Capdevila, J., Elez, E., Tabernero, J., (2009), 1 (6), pp. 965-968. , Immunotherapy New trends in epidermal growth factor receptor-directed monoclonal antibodies
(): -Blanc, V., Bousseau, A., Caron, A., Carrez, C., Lutz, R.J., Lambert, J.M., SAR3419: an anti-CD19-Maytansinoid Immunoconjugate for the treatment of B-cell malignancies (2011) Clin. Cancer Res., 17 (20), pp. 6448-6458
Steiner, M., Neri, D., Antibody-radionuclide conjugates for cancer therapy: historical considerations and new trends (2011) Clin. Cancer Res., 17, pp. 6406-6416
Ronca, R., Sozzani, S., Presta, M., Alessi, P., Delivering cytokines at tumor site: The immunocytokine-conjugated anti-EDB-fibronectin antibody case (2009) Immunobiology, 214 (9-10), pp. 800-810
Gregoriadis, G., Ryman, B.E., Lysosomal localization of β-fructofuranosidase-containing liposomes injected into rats. Some implications in the treatment of genetic disorders (1972) Biochem. J., 129, pp. 123-133
Banciu, M., Schiffelers, R.M., Storm, G., Investigation into the role of tumor-associated macrophages in the antitumor activity of doxil (2008) Pharm. Res., 25, pp. 1948-1955
Marcucci, F., Lefoulon, F., Active targeting with particulate drug carriers in tumor therapy: fundamentals and recent progress (2004) Drug Discov. Today, 9, pp. 219-228
Torchilin, V.P., Antibody-modified liposomes for cancer chemotherapy (2008) Expert Opin. Drug Delivery, 5, pp. 1003-1025
Sofou, S., Sgouros, G., Antibody-targeted liposomes in cancer therapy and imaging (2008) Expert Opin. Drug Delivery, 5, pp. 189-204
Wu, H.-C., Chang, D.-K., Peptide-Mediated Liposomal Drug Delivery System Targeting Tumor Blood Vessels in Anticancer Therapy (2010) J. Oncol., , article ID: 723798
DOI:10.1155/2010/723798
Falciani, C., Accardo, A., Brunetti, J., Tesauro, D., Lelli, B., Pini, A., Bracci, L., Morelli, G., Target-selective drug delivery through liposomes labeled with oligobranched neurotensin peptides (2011) ChemMedChem, 6 (4), pp. 678-685
Bracci, L., Falciani, C., Lelli, B., Lozzi, L., Runci, Y., Pini, A., De Montis, M.G., Neri, P., Synthetic peptides in the form of dendrimers become resistant to protease activity (2003) J. Biol. Chem., 278 (47), pp. 46590-46595
Falciani, C., Lozzi, L., Pini, A., Corti, F., Fabbrini, M., Bernini, A., Lelli, B., Bracci, L., Molecular basis of branched peptides resistance to enzyme proteolysis (2007) Chem. Biol. Drug Des., 69 (3), pp. 216-221
Falciani, C., Brunetti, J., Pagliuca, C., Menichetti, S., Vitellozzi, L., Lelli, B., Pini, A., Bracci, L., Design and in vitro evaluation of branched peptide conjugates: turning nonspecific cytotoxic drugs into tumor-selective agents (2010) ChemMedChem, 5 (4), pp. 567-574
Falciani, C., Pini, A., Bracci, L., Oligo-branched peptides for tumor targeting: from magic bullets to magic forks (2009) Expert Opin. Biol. Ther., 9 (2), pp. 171-178
Falciani, C., Fabbrini, M., Pini, A., Lozzi, L., Lelli, B., Pileri, S., Brunetti, J., Bracci, L., Synthesis and biological activity of stable branched neurotensin peptides for tumor targeting (2007) Mol. Cancer Ther., 6 (9), pp. 2441-2448
Minervini, A., Siena, G., Falciani, C., Carini, M., Bracci, L., Branched peptides as novel tumor-targeting agents for bladder cancer (2012) Expert Rev. Anticancer Ther., 12 (6), pp. 699-701
Chan, W.C., White, P.D., (2000) Fmoc Solid Phase Peptide Synthesis, , Oxford University Press: New York
Schmitt, L., Dietrich, C., Synthesis and characterization of chelator lipids for reversible immobilization of engineered proteins at self assembled lipid interfaces (1994) J. Am. Chem. Soc., 116, pp. 8485-8491
(): -Blanc, V., Bousseau, A., Caron, A., Carrez, C., Lutz, R. J., Lambert, J. M., SAR3419: an anti-CD19-Maytansinoid Immunoconjugate for the treatment of B-cell malignancies (2011) Clin. Cancer Res., 17 (20), pp. 6448-6458
Torchilin, V. P., Antibody-modified liposomes for cancer chemotherapy (2008) Expert Opin. Drug Delivery, 5, pp. 1003-1025
Wu, H. -C., Chang, D. -K., Peptide-Mediated Liposomal Drug Delivery System Targeting Tumor Blood Vessels in Anticancer Therapy (2010) J. Oncol., , article ID: 723798
DOI: 10. 1155/2010/723798
Chan, W. C., White, P. D., (2000) Fmoc Solid Phase Peptide Synthesis, , Oxford University Press: New York
J Pept Sci (ISSN: 1075-2617, 1099-1387, 1075-2617print), 2013 Apr; 19(4): 198-204.
Export to BibTeX Export to EndNote
Paper type: Journal Article,
Impact factor: 1.862, 5-year impact factor: 1.715
Url: http://www.scopus.com/inward/record.url?eid=2-s2.0-84875632201&partnerID=40&md5=9fad6e962fe3d586545ed859cd400a62
Keywords: Branched Peptides, Doxorubicin, Liposome, Tumor-Targeting, Anthracycline, Linear Neurotensin Peptide Nt, Nanoparticle, Tetrabranched Neurotensin Peptide Nt4, Unclassified Drug, Cell Fusion, Cell Membrane, Controlled Study, Cytotoxicity, Drug Delivery System, Drug Protein Binding, Human, Human Cell, Internalization, Priority Journal, Target Cell, Tumor Cell, Antibiotics, Antineoplastic, Cell Line,
Affiliations:
*** IBB - CNR ***
Department of Medical Biotechnology, University of Siena, Via Fiorentina 1, Siena, 53100, Italy
Department of Pharmacy, Centro Interuniversitario di Ricerca sui Peptidi Bioattivi, University of Naples 'Federico II', Istituto di Biostrutture e Bioimmagin, CNR, Via Mezzocannone 16, Naples, 80134, Italy
Istituto Toscano Tumori, Siena, Italy
References:
Ohanian, M., Cortes, J., Kantarjian, H., Jabbour, E., Tyrosine kinase inhibitors in acute and chronic leukemias (2012) Expert Opin. Pharmacother., 13 (7), pp. 927-93
Markman, B., Capdevila, J., Elez, E., Tabernero, J., (2009), 1 (6), pp. 965-968. , Immunotherapy New trends in epidermal growth factor receptor-directed monoclonal antibodies
(): -Blanc, V., Bousseau, A., Caron, A., Carrez, C., Lutz, R.J., Lambert, J.M., SAR3419: an anti-CD19-Maytansinoid Immunoconjugate for the treatment of B-cell malignancies (2011) Clin. Cancer Res., 17 (20), pp. 6448-6458
Steiner, M., Neri, D., Antibody-radionuclide conjugates for cancer therapy: historical considerations and new trends (2011) Clin. Cancer Res., 17, pp. 6406-6416
Ronca, R., Sozzani, S., Presta, M., Alessi, P., Delivering cytokines at tumor site: The immunocytokine-conjugated anti-EDB-fibronectin antibody case (2009) Immunobiology, 214 (9-10), pp. 800-810
Gregoriadis, G., Ryman, B.E., Lysosomal localization of β-fructofuranosidase-containing liposomes injected into rats. Some implications in the treatment of genetic disorders (1972) Biochem. J., 129, pp. 123-133
Banciu, M., Schiffelers, R.M., Storm, G., Investigation into the role of tumor-associated macrophages in the antitumor activity of doxil (2008) Pharm. Res., 25, pp. 1948-1955
Marcucci, F., Lefoulon, F., Active targeting with particulate drug carriers in tumor therapy: fundamentals and recent progress (2004) Drug Discov. Today, 9, pp. 219-228
Torchilin, V.P., Antibody-modified liposomes for cancer chemotherapy (2008) Expert Opin. Drug Delivery, 5, pp. 1003-1025
Sofou, S., Sgouros, G., Antibody-targeted liposomes in cancer therapy and imaging (2008) Expert Opin. Drug Delivery, 5, pp. 189-204
Wu, H.-C., Chang, D.-K., Peptide-Mediated Liposomal Drug Delivery System Targeting Tumor Blood Vessels in Anticancer Therapy (2010) J. Oncol., , article ID: 723798
DOI:10.1155/2010/723798
Falciani, C., Accardo, A., Brunetti, J., Tesauro, D., Lelli, B., Pini, A., Bracci, L., Morelli, G., Target-selective drug delivery through liposomes labeled with oligobranched neurotensin peptides (2011) ChemMedChem, 6 (4), pp. 678-685
Bracci, L., Falciani, C., Lelli, B., Lozzi, L., Runci, Y., Pini, A., De Montis, M.G., Neri, P., Synthetic peptides in the form of dendrimers become resistant to protease activity (2003) J. Biol. Chem., 278 (47), pp. 46590-46595
Falciani, C., Lozzi, L., Pini, A., Corti, F., Fabbrini, M., Bernini, A., Lelli, B., Bracci, L., Molecular basis of branched peptides resistance to enzyme proteolysis (2007) Chem. Biol. Drug Des., 69 (3), pp. 216-221
Falciani, C., Brunetti, J., Pagliuca, C., Menichetti, S., Vitellozzi, L., Lelli, B., Pini, A., Bracci, L., Design and in vitro evaluation of branched peptide conjugates: turning nonspecific cytotoxic drugs into tumor-selective agents (2010) ChemMedChem, 5 (4), pp. 567-574
Falciani, C., Pini, A., Bracci, L., Oligo-branched peptides for tumor targeting: from magic bullets to magic forks (2009) Expert Opin. Biol. Ther., 9 (2), pp. 171-178
Falciani, C., Fabbrini, M., Pini, A., Lozzi, L., Lelli, B., Pileri, S., Brunetti, J., Bracci, L., Synthesis and biological activity of stable branched neurotensin peptides for tumor targeting (2007) Mol. Cancer Ther., 6 (9), pp. 2441-2448
Minervini, A., Siena, G., Falciani, C., Carini, M., Bracci, L., Branched peptides as novel tumor-targeting agents for bladder cancer (2012) Expert Rev. Anticancer Ther., 12 (6), pp. 699-701
Chan, W.C., White, P.D., (2000) Fmoc Solid Phase Peptide Synthesis, , Oxford University Press: New York
Schmitt, L., Dietrich, C., Synthesis and characterization of chelator lipids for reversible immobilization of engineered proteins at self assembled lipid interfaces (1994) J. Am. Chem. Soc., 116, pp. 8485-8491
(): -Blanc, V., Bousseau, A., Caron, A., Carrez, C., Lutz, R. J., Lambert, J. M., SAR3419: an anti-CD19-Maytansinoid Immunoconjugate for the treatment of B-cell malignancies (2011) Clin. Cancer Res., 17 (20), pp. 6448-6458
Torchilin, V. P., Antibody-modified liposomes for cancer chemotherapy (2008) Expert Opin. Drug Delivery, 5, pp. 1003-1025
Wu, H. -C., Chang, D. -K., Peptide-Mediated Liposomal Drug Delivery System Targeting Tumor Blood Vessels in Anticancer Therapy (2010) J. Oncol., , article ID: 723798
DOI: 10. 1155/2010/723798
Chan, W. C., White, P. D., (2000) Fmoc Solid Phase Peptide Synthesis, , Oxford University Press: New York
Nanoparticles exposing neurotensin tumor-specific drivers
Nanoparticles have attracted much attention for their potential application as in vivo carriers of drugs. Labeling of nanoparticles with bioactive markers that are able to direct them toward specific biological target receptors has led to a new generation of drug delivery systems. In particular, low molecular weight peptides that remain stablein vivo could be promising tools to selectively drive nanoparticles loaded with active components to tumor cells. We reported, recently, that tetrabranched neurotensin peptides (NT4) may be used to selectively target tumor cells with liposomes. Liposomes functionalized with tetrabranched neurotensin peptide, NT4, and loaded with doxorubicin showed clear advantages in cell binding, anthracyclin internalization, and cytotoxicity in respect of not functionalized liposomes. In this study, we compare branched (NT4) versus linear (NT) peptides in the ability to drive liposomes to target cells and deliver their toxic cargo. We showed here that the more densely decorated liposomes had a better activity profile in terms of drug delivery. Presentation of peptides to the cell membranes in the grouped shape provided by branched structure facilitates liposome cell binding and fusion. © 2013 European Peptide Society and John Wiley & Sons, Ltd.
Nanoparticles have attracted much attention for their potential application as in vivo carriers of drugs. Labeling of nanoparticles with bioactive markers that are able to direct them toward specific biological target receptors has led to a new generation of drug delivery systems. In particular, low molecular weight peptides that remain stablein vivo could be promising tools to selectively drive nanoparticles loaded with active components to tumor cells. We reported, recently, that tetrabranched neurotensin peptides (NT4) may be used to selectively target tumor cells with liposomes. Liposomes functionalized with tetrabranched neurotensin peptide, NT4, and loaded with doxorubicin showed clear advantages in cell binding, anthracyclin internalization, and cytotoxicity in respect of not functionalized liposomes. In this study, we compare branched (NT4) versus linear (NT) peptides in the ability to drive liposomes to target cells and deliver their toxic cargo. We showed here that the more densely decorated liposomes had a better activity profile in terms of drug delivery. Presentation of peptides to the cell membranes in the grouped shape provided by branched structure facilitates liposome cell binding and fusion. © 2013 European Peptide Society and John Wiley & Sons, Ltd.
Nanoparticles exposing neurotensin tumor-specific drivers
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Nanoparticles exposing neurotensin tumor-specific drivers
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Hesse B, Lindhardt TB, Acampa W, Anagnostopoulos C, Ballinger J, Bax JJ, Edenbrandt L, Flotats A, Germano G, Stopar TG, Franken P, Kelion A, Kjaer A, Le Guludec D, Ljungberg M, Maenhout AF, Marcassa C, Marving J, Mckiddie F, Schaefer WM, Stegger L, Underw
* EANM/ESC guidelines for radionuclide imaging of cardiac function (572 views)
Eur J Nucl Med (ISSN: 1619-7070, 1619-7089, 0340-6997), 2008 Apr; 35(4): 851-885.
Impact Factor: 4.532
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Saviano M, De Luca S, Morelli G, Tesauro D, Pedone C
* Preparation and use of cyclic and branched peptides and their labelled derivatives as therapeutic agents, cholecystokinin agonists or antagonists, and diagnostic agents to identify and locate tumours (432 views)
Patents Official Gazette Of The United States Patent And Trademark Office (ISSN: 0098-1133), 2008 Feb 12; N/D: N/D-N/D.
Impact Factor: 0
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Calabrese V, Mancuso C, Calvani M, Rizzarelli E, Butterfield DA, Stella AM
* Nitric oxide in the central nervous system: neuroprotection versus neurotoxicity (753 views)
Nature Reviews Neuroscience (ISSN: 1471-0048), 2007 Oct; 8(10): 766-775.
Impact Factor: 24.52
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Accardo A, Tesauro D, Mangiapia G, Pedone C, Morelli G
* Nanostructures by self-assembling peptide amphiphile as potential selective drug carriers (429 views)
Biopolymers (ISSN: 0006-3525, 0006-6352, 0006-3525print), 2007; 88(2): 115-121.
Impact Factor: 2.389
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De Renzo A, Perna F, Persico M, Mainolfi C, Pace L
* 18F-fluorodeoxyglucose positron emission tomography/computed tomography in the evaluation of early response in a primary hepatic lymphoma (233 views)
Br J Haematol (ISSN: 0007-1048, 0007-1048linking, 1365-2141electronic), 2006 Jun; 133(6): 580-580.
Impact Factor: 4.498
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Mainenti PP, Romano L, Contegiacomo A, Romano M, Casella V, Cuccuru A, Insabato L, Salvatore M
* Rare diffuse peritoneal malignant neoplasms: CT findings in two cases (246 views)
Abdom Imaging (ISSN: 0942-8925, 1432-0509), 2003 Nov; 28(6): 827-830.
Impact Factor: 0.996
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Portella G, Pacelli R, Libertini S, Cella L, Vecchio G, Salvatore M, Fusco A
* ONYX-015 Enhances Radiation-Induced Death of Human Anaplastic Thyroid Carcinoma Cells (467 views)
J Clin Endocrinol Metab Journal Of Clinical Endocrinology And Metabolism (ISSN: 0021-972x), 2003 Oct 1; 88(10): 5027-5032.
Impact Factor: 5.873
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Tauchmanova L, De Rosa G, Serio B, Fazioli F, Mainolfi C, Lombardi G, Colao A, Salvatore M, Rotoli B, Selleri C
* Avascular necrosis in long-term survivors after allogeneic or autologous stem cell transplantation: A single center experience and a review (277 views)
Cancer (ISSN: 0008-543x), 2003 May 15; 97(10): 2453-2461.
Impact Factor: 2.045
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Acampa W, Petretta M, Cuocolo A
* Nuclear medicine procedures in cardiovascular diseases: An evidence based approach (467 views)
Q J Nucl Med (ISSN: 1124-3937, 1125-0135), 2002 Dec; 46(4): 323-330.
Impact Factor: 1.903
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Levchenko A, Mehta B, Spengler BA, Narkar A, Fonti R, Biedler JL, Tsuruo T, Larson SM
Measurement of P-glycoprotein expression in multidrug-resistant human neuroblastoma cell lines using self-competitive binding assay (283 views)
Anal Biochem (ISSN: 0003-2697, 1096-0309electronic, 0003-2697linking), 1996 May 1; 236(2): 338-343.
Impact Factor: 2.017
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MAUREA S, LASTORIA S, CARACO C, INDOLFI P, CASALE F, DITULLIO M, SALVATORE M
IODINE-131-MIBG IMAGING TO MONITOR CHEMOTHERAPY RESPONSE IN ADVANCED NEUROBLASTOMA - COMPARISON WITH LABORATORY ANALYSIS (328 views)
J Nucl Med (ISSN: 0161-5505, 1535-5667, 1535-5667electronic), 1994 Sep; 35(9): 1429-1435.
Impact Factor: 3.491
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Correale P, Caraglia M, Pepe S, Ricciardi B, Barile C, Montagnani S, Pacelli R, Bianco A, Tagliaferri P
PHORBOL 12-MYRISTATE 13-ACETATE (PMA) INDUCES NEUROENDOCRINE-LIKE DIFFERENTIATION AND REVERSES DOXORUBICIN-RESISTANCE OF HUMAN COLON-CARCINOMA CELLS IN-VITRO (299 views)
Int J Oncol (ISSN: 1019-6439, 1791-2423electronic, 1019-6439linking), 1994 Feb; 4(2): 423-427.
Impact Factor: 1.181
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Scala S, Pacelli R, Iaffaioli RV, Normanno N, Pepe S, Frasci G, Genua G, Tsuruo T, Tagliaferri P, Bianco AR
Reversal of adriamycin resistance by recombinant α-interferon in multidrug-resistant human colon carcinoma LoVo-doxorubicin cells (559 views)
Cancer Res (ISSN: 0008-5472, 1538-7445, 1538-7445electronic), 1991 Sep 15; 51(18): 4898-4902.
Impact Factor: 8.426
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* GlucoCEST MRI for the Evaluation Response to Chemotherapeutic and Metabolic Treatments in a Murine Triple-Negative Breast Cancer: A Comparison with[(18)F]F-FDG-PET (12 views)
Mol Imaging Biol (ISSN: 1536-1632linking), 2021 Aug 12; N/D: N/D-N/D.
Impact Factor:
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Mercurio V, Cuomo A, Della Pepa R, Ciervo D, Cella L, Pirozzi F, Parrella P, Campi G, Franco R, Varricchi G, Abete P, Marone G, Petretta M, Bonaduce D, Pacelli R, Picardi M, Tocchetti CG
* What Is the Cardiac Impact of Chemotherapy and Subsequent Radiotherapy in Lymphoma Patients? (182 views)
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Impact Factor: 7.581
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Oliveri V, Bellia F, Viale M, Maric I, Vecchio G
* Linear polymers of beta and gamma cyclodextrins with a polyglutamic acid backbone as carriers for doxorubicin (464 views)
Carbohyd Polym (ISSN: 0144-8617), 2017 Dec 1; 177: 355-360.
Impact Factor: 5.158
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Diaferia C, Gianolio E, Sibillano T, Mercurio FA, Leone M, Giannini C, Balasco N, Vitagliano L, Morelli G, Accardo A
* Cross-beta nanostructures based on dinaphthylalanine Gd-conjugates loaded with doxorubicin (413 views)
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Impact Factor: 4.122
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Accardo A, Arena F, Gianolio E, Marasco D, Ringhieri P, Boffa C, Bardini P, Aime S, Morelli G
* Diolein based nanostructures as targeted theranostics (446 views)
J Biomed Nanotechnol (ISSN: 1550-7033), 2016; 12(5): 1076-1088.
Impact Factor: 4.521
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Cella L, Oh JH, Deasy JO, Palma G, Liuzzi R, D'Avino V, Conson M, Picardi M, Salvatore M, Pacelli R
* Predicting radiation-induced valvular heart damage (331 views)
Acta Oncol (ISSN: 0284-186x, 0284-186xlinking), 2015 Mar 24; 54(10): 1796-1804.
Impact Factor: 3.73
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Rizzitelli S, Giustetto P, Cutrin JC, Delli Castelli D, Boffa C, Ruzza M, Menchise V, Molinari F, Aime S, Terreno E
* Sonosensitive theranostic liposomes for preclinical in vivo MRI-guided visualization of doxorubicin release stimulated by pulsed low intensity non-focused ultrasound (470 views)
J Control Release (ISSN: 0168-3659), 2015 Jan 24; 202: 21-30.
Impact Factor: 7.441
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Galdiero S, Falanga A, Morelli G, Galdiero M
* gH625: A milestone in understanding the many roles of membranotropic peptides (524 views)
Bba-Gen Subjects (ISSN: 0925-4439, 0006-3002, 1570-9639), 2015 Jan; 1848(PA): 16-25.
Impact Factor: 5.158
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Ringhieri P, Diaferia C, Galdiero S, Palumbo R, Morelli G, Accardo A
* Liposomal doxorubicin doubly functionalized with CCK8 and R8 peptide sequences for selective intracellular drug delivery (451 views)
J Pept Sci (ISSN: 1075-2617, 1099-1387, 1075-2617linking), 2015; 21(5): 415-425.
Impact Factor: 1.951
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Galdiero S, Falanga A, Vitiello M, Grieco P, Caraglia M, Morelli G, Galdiero M
* Exploitation of viral properties for intracellular delivery (508 views)
J Pept Sci (ISSN: 1075-2617, 1099-1387, 1075-2617linking), 2014 Jul; 20(7): 468-478.
Impact Factor: 1.546
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Gallicchio R, Mansueto G, Simeon V, Nardelli A, Guariglia R, Capacchione D, Soscia E, Pedicini P, Gattozzi D, Musto P, Storto G
* F-18 FDG PET/CT quantization parameters as predictors of outcome in patients with diffuse large B-cell lymphoma (531 views)
Eur J Haematol (ISSN: 0902-4441), 2014 May; 92(5): 382-389.
Impact Factor: 2.066
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Cella L, Liuzzi R, D'Avino V, Conson M, Di Biase A, Picardi M, Pugliese N, Solla R, Salvatore M, Pacelli R
* Pulmonary damage in Hodgkin's lymphoma patients treated with sequential chemo-radiotherapy: Predictors of radiation-induced lung injury (378 views)
Acta Oncol (ISSN: 0284-186x), 2014 May; 53(5): 613-619.
Impact Factor: 2.997
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Accardo A, Ringhieri P, Szekely N, Pipich V, Luchini A, Paduano L, Tesauro D
* Structural insights on nanoparticles containing gadolinium complexes as potential theranostic (454 views)
Colloid Polym Sci (ISSN: 0303-402x), 2014 May; 292(5): 1121-1127.
Impact Factor: 1.865
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Accardo A, Aloj L, Aurilio M, Morelli G, Tesauro D
* Receptor binding peptides for target-selective delivery of nanoparticles encapsulated drugs (571 views)
Int J Nanomed (ISSN: 1178-2013, 1176-9114, 1176-9114linking), 2014 Mar 27; 9(1): 1537-1557.
Impact Factor: 4.383
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Rami M, Dubois L, Parvathaneni NK, Alterio V, van Kuijk SJ, Monti SM, Lambin P, De Simone G, Supuran CT, Winum JY
* Hypoxia-targeting carbonic anhydrase IX inhibitors by a new series of nitroimidazole-sulfonamides/sulfamides/sulfamates (546 views)
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Impact Factor: 5.48
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Accardo A, Tesauro D, Morelli G
* Peptide-based targeting strategies for simultaneous imaging and therapy with nanovectors (484 views)
Polym J (ISSN: 0032-3896), 2013 May; 45(5): 481-493.
Impact Factor: 1.554
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Accardo A, Mangiapia G, Paduano L, Morelli G, Tesauro D
* Octreotide labeled aggregates containing platinum complexes as nanovectors for drug delivery (408 views)
J Pept Sci (ISSN: 1075-2617, 1099-1387, 1075-2617print), 2013 Apr; 19(4): 190-197.
Impact Factor: 1.862
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Accardo A, Ringhieri P, Tesauro D, Morelli G
* Liposomes derivatized with tetrabranched neurotensin peptides via click chemistry reactions (397 views)
New J Chem (ISSN: 1144-0546), 2013; 37(11): 3528-3534.
Impact Factor: 3.159
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Accardo A, Mansi R, Salzano G, Morisco A, Aurilio M, Parisi A, Maione F, Cicala C, Ziaco B, Tesauro D, Aloj L, De Rosa G, Morelli G
* Bombesin peptide antagonist for target-selective delivery of liposomal doxorubicin on cancer cells (410 views)
Journal Of Drug Targeting (ISSN: 1061-186x), 2012 Nov 21; 21(3): 240-249.
Impact Factor: 2.768
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Cella L, Conson M, Caterino M, De Rosa N, Liuzzi R, Picardi M, Grimaldi F, Solla R, Farella A, Salvatore M, Pacelli R
* Thyroid V30 predicts radiation-induced hypothyroidism in patients treated with sequential chemo-radiotherapy for Hodgkin's lymphoma (490 views) (PDF 236 views)
Int J Radiat Oncol (ISSN: 0360-3016, 1879-355x, 1879-355xelectronic), 2012 Apr 1; 82(5): 1802-1808.
Impact Factor: 4.524
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Accardo A, Salsano G, Morisco A, Aurilio M, Parisi A, Maione F, Cicala C, Tesauro D, Aloj L, De Rosa G, Morelli G
* Peptide-modified liposomes for selective targeting of bombesin receptors overexpressed by cancer cells: A potential theranostic agent (381 views)
Int J Nanomed (ISSN: 1176-9114, 1178-2013, 1178-2013electronic), 2012; 7: 2007-2017.
Impact Factor: 3.463
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Tarallo R, Accardo A, Falanga A, Guarnieri D, Vitiello G, Netti P, D'Errico G, Morelli G, Galdiero S
* Clickable functionalization of liposomes with the gH625 peptide from herpes simplex virus type i for intracellular drug delivery (457 views)
Chemistry (ISSN: 0947-6539, 1521-3765, 1521-3765electronic), 2011 Nov 4; 17(45): 12659-12668.
Impact Factor: 5.925
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Cella L, Liuzzi R, Conson M, Torre G, Caterino M, De Rosa N, Picardi M, Camera L, Solla R, Farella A, Salvatore M, Pacelli R
* Dosimetric predictors of asymptomatic heart valvular dysfunction following mediastinal irradiation for Hodgkin's lymphoma (440 views)
Radiother Oncol (ISSN: 0167-8140, 1879-0887, 1879-0887electronic), 2011 Nov; 101(2): 316-321.
Impact Factor: 5.58
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Ruvo M, Sandomenico A, Tudisco L, De Falco S
* Branched peptides for the modulation of protein-protein interactions: More arms are better than one? (524 views)
Curr Med Chem (ISSN: 0929-8673, 1875-533x, 1875-533xelectronic), 2011 Jun; 18(16): 2429-2437.
Impact Factor: 4.859
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Cuocolo A
Current research in nuclear medicine and molecular imaging in Italy: Highlights of the 10th National Congress of the Italian Association of Nuclear Medicine and Molecular Imaging (463 views)
Q J Nucl Med Mol Im (ISSN: 1824-4785, 1824-4478, 1824-4785linking), 2011 Jun; 55(3): 280-300.
Impact Factor: 1.724
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Falciani C, Accardo A, Brunetti J, Tesauro D, Lelli B, Pini A, Bracci L, Morelli G
* Target-Selective Drug Delivery through Liposomes Labeled with Oligobranched Neurotensin Peptides (561 views)
Chemmedchem (ISSN: 1860-7179, 1860-7187, 1860-7187electronic), 2011 Apr 4; 6(4): 678-685.
Impact Factor: 3.151
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Accardo A, Morisco A, Tesauro D, Pedone C, Morelli G
* Naposomes: A new class of peptide-derivatized, target-selective multimodal nanoparticles for imaging and therapeutic applications (408 views)
Ther Deliv (ISSN: 2041-5990), 2011 Feb; 2(2): 235-257.
Impact Factor: 0
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Morisco A, Accardo A, Tesauro D, Palumbo R, Benedetti E, Morelli G
* Peptide-labeled supramolecular aggregates as selective doxorubicin carriers for delivery to tumor cells (360 views)
Biopolymers (ISSN: 0006-3525, 0006-6352, 0006-3525print), 2011; 96(1): 88-96.
Impact Factor: 2.87
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Strianese D, Tranfa F, Finelli M, De Renzo A, Staibano S, Schiemer R, Cardone D, Pacelli R, Perna F, Mascolo M, De Rosa G, Bonavolonta G
* Hepatitis C virus infection in ocular adnexal lymphomas (353 views)
Arch Ophthalmol (ISSN: 1538-3601, 0003-9950), 2010 Oct; 128(10): 1295-1299.
Impact Factor: 3.516
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Gallucci G, Coccaro M, Storto G, Lapadula L, Tartarone A, Nappi A, Cammarota A, Buonerba C, Di Lorenzo G, Fusco V, Aieta M
* The clinical impact of a cardiologic follow-up in breast cancer survivors: an observational study (293 views)
Int J Immunopathol Pharmacol (ISSN: 0394-6320), 2010 Oct; 23(4): 1221-1227.
Impact Factor: 2.685
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Del Vecchio S, Zannetti A, Fonti R, Iommelli F, Pizzuti LM, Lettieri A, Salvatore M
* PET/CT in cancer research: From preclinical to clinical applications (617 views)
Contrast Media Mol Imaging (ISSN: 1555-4309, 1555-4309linking), 2010 Jul; 5(4): 190-200.
Impact Factor: 4.02
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Kelly SE, Di Benedetto A, Greco A, Howard CM, Sollars VE, Primerano DA, Valluri JV, Claudio PP
* Rapid Selection and Proliferation of CD133(+) Cells from Cancer Cell Lines: Chemotherapeutic Implications (457 views)
Plosone (ISSN: 1932-6203, 1932-6203electronic, 1932-6203linking), 2010 Apr 8; 5(4): N/D-N/D.
Impact Factor: 4.411
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Storto G, De Renzo A, Pellegrino T, Perna F, De Falco T, Erra P, Nardelli A, Speranza A, Klain M, Rotoli B, Pace L
* Assessment of Metabolic Response to Radioimmunotherapy with (90)Y-Ibritumomab Tiuxetan in Patients with Relapsed or Refractory B-Cell Non-Hodgkin Lymphoma (399 views)
Radiology (ISSN: 0033-8419, 1527-1315, 0033-8419linking), 2010 Jan; 254(1): 245-252.
Impact Factor: 6.069
View Export to BibTeX Export to EndNote
Hesse B, Lindhardt TB, Acampa W, Anagnostopoulos C, Ballinger J, Bax JJ, Edenbrandt L, Flotats A, Germano G, Stopar TG, Franken P, Kelion A, Kjaer A, Le Guludec D, Ljungberg M, Maenhout AF, Marcassa C, Marving J, Mckiddie F, Schaefer WM, Stegger L, Underw
* EANM/ESC guidelines for radionuclide imaging of cardiac function (572 views)
Eur J Nucl Med (ISSN: 1619-7070, 1619-7089, 0340-6997), 2008 Apr; 35(4): 851-885.
Impact Factor: 4.532
View Export to BibTeX Export to EndNote
Saviano M, De Luca S, Morelli G, Tesauro D, Pedone C
* Preparation and use of cyclic and branched peptides and their labelled derivatives as therapeutic agents, cholecystokinin agonists or antagonists, and diagnostic agents to identify and locate tumours (432 views)
Patents Official Gazette Of The United States Patent And Trademark Office (ISSN: 0098-1133), 2008 Feb 12; N/D: N/D-N/D.
Impact Factor: 0
View Export to BibTeX Export to EndNote
Calabrese V, Mancuso C, Calvani M, Rizzarelli E, Butterfield DA, Stella AM
* Nitric oxide in the central nervous system: neuroprotection versus neurotoxicity (753 views)
Nature Reviews Neuroscience (ISSN: 1471-0048), 2007 Oct; 8(10): 766-775.
Impact Factor: 24.52
View Export to BibTeX Export to EndNote
Accardo A, Tesauro D, Mangiapia G, Pedone C, Morelli G
* Nanostructures by self-assembling peptide amphiphile as potential selective drug carriers (429 views)
Biopolymers (ISSN: 0006-3525, 0006-6352, 0006-3525print), 2007; 88(2): 115-121.
Impact Factor: 2.389
View Export to BibTeX Export to EndNote
De Renzo A, Perna F, Persico M, Mainolfi C, Pace L
* 18F-fluorodeoxyglucose positron emission tomography/computed tomography in the evaluation of early response in a primary hepatic lymphoma (233 views)
Br J Haematol (ISSN: 0007-1048, 0007-1048linking, 1365-2141electronic), 2006 Jun; 133(6): 580-580.
Impact Factor: 4.498
View Export to BibTeX Export to EndNote
Mainenti PP, Romano L, Contegiacomo A, Romano M, Casella V, Cuccuru A, Insabato L, Salvatore M
* Rare diffuse peritoneal malignant neoplasms: CT findings in two cases (246 views)
Abdom Imaging (ISSN: 0942-8925, 1432-0509), 2003 Nov; 28(6): 827-830.
Impact Factor: 0.996
View Export to BibTeX Export to EndNote
Portella G, Pacelli R, Libertini S, Cella L, Vecchio G, Salvatore M, Fusco A
* ONYX-015 Enhances Radiation-Induced Death of Human Anaplastic Thyroid Carcinoma Cells (467 views)
J Clin Endocrinol Metab Journal Of Clinical Endocrinology And Metabolism (ISSN: 0021-972x), 2003 Oct 1; 88(10): 5027-5032.
Impact Factor: 5.873
View Export to BibTeX Export to EndNote
Tauchmanova L, De Rosa G, Serio B, Fazioli F, Mainolfi C, Lombardi G, Colao A, Salvatore M, Rotoli B, Selleri C
* Avascular necrosis in long-term survivors after allogeneic or autologous stem cell transplantation: A single center experience and a review (277 views)
Cancer (ISSN: 0008-543x), 2003 May 15; 97(10): 2453-2461.
Impact Factor: 2.045
View Export to BibTeX Export to EndNote
Acampa W, Petretta M, Cuocolo A
* Nuclear medicine procedures in cardiovascular diseases: An evidence based approach (467 views)
Q J Nucl Med (ISSN: 1124-3937, 1125-0135), 2002 Dec; 46(4): 323-330.
Impact Factor: 1.903
View Export to BibTeX Export to EndNote
Levchenko A, Mehta B, Spengler BA, Narkar A, Fonti R, Biedler JL, Tsuruo T, Larson SM
Measurement of P-glycoprotein expression in multidrug-resistant human neuroblastoma cell lines using self-competitive binding assay (283 views)
Anal Biochem (ISSN: 0003-2697, 1096-0309electronic, 0003-2697linking), 1996 May 1; 236(2): 338-343.
Impact Factor: 2.017
View Export to BibTeX Export to EndNote
MAUREA S, LASTORIA S, CARACO C, INDOLFI P, CASALE F, DITULLIO M, SALVATORE M
IODINE-131-MIBG IMAGING TO MONITOR CHEMOTHERAPY RESPONSE IN ADVANCED NEUROBLASTOMA - COMPARISON WITH LABORATORY ANALYSIS (328 views)
J Nucl Med (ISSN: 0161-5505, 1535-5667, 1535-5667electronic), 1994 Sep; 35(9): 1429-1435.
Impact Factor: 3.491
View Export to BibTeX Export to EndNote
Correale P, Caraglia M, Pepe S, Ricciardi B, Barile C, Montagnani S, Pacelli R, Bianco A, Tagliaferri P
PHORBOL 12-MYRISTATE 13-ACETATE (PMA) INDUCES NEUROENDOCRINE-LIKE DIFFERENTIATION AND REVERSES DOXORUBICIN-RESISTANCE OF HUMAN COLON-CARCINOMA CELLS IN-VITRO (299 views)
Int J Oncol (ISSN: 1019-6439, 1791-2423electronic, 1019-6439linking), 1994 Feb; 4(2): 423-427.
Impact Factor: 1.181
View Export to BibTeX Export to EndNote
Scala S, Pacelli R, Iaffaioli RV, Normanno N, Pepe S, Frasci G, Genua G, Tsuruo T, Tagliaferri P, Bianco AR
Reversal of adriamycin resistance by recombinant α-interferon in multidrug-resistant human colon carcinoma LoVo-doxorubicin cells (559 views)
Cancer Res (ISSN: 0008-5472, 1538-7445, 1538-7445electronic), 1991 Sep 15; 51(18): 4898-4902.
Impact Factor: 8.426
View Export to BibTeX Export to EndNote
46 Records (44 excluding Abstracts).
Total impact factor: 182.01 (173.101 excluding Abstracts).
Total 5 year impact factor: 188.3 (178.815 excluding Abstracts).
Total impact factor: 182.01 (173.101 excluding Abstracts).
Total 5 year impact factor: 188.3 (178.815 excluding Abstracts).
448 views. Last view on Thursday 19 January 2023, 11:47:07
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