Kinetics and mechanism of the cleavage of the peptide bond next to asparagine (362 views)
Peptides (ISSN: 0196-9781, 1873-5169electronic, 0196-9781linking), 1996; 17(6): 1075-1077.
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Paper type: Journal Article,
Impact factor: 1.738, 5-year impact factor: 2.372
Url: http://www.scopus.com/inward/record.url?eid=2-s2.0-0029855624&partnerID=40&md5=b9e898a230bbe70b8933cdf7d088e19e
Keywords: Asparagine, Deamidation, Peptide Bond Cleavage, Succinimide, Article, Peptide Analysis, Priority Journal, Protein Processing, Kinetics, Models, Chemical, Oligopeptides, Protein Splicing,
Affiliations:
Ctro. di Studio di B., CNR, Napoli, Italy
Facoltà di Sci. Ambientali, Seconda Università di Napoli, Caserta, Italy
Dipto. di Scienze Farmaceutiche, Università di Ferrara, Ferrara, Italy
University Chemical Laboratory, Cambridge, United Kingdom
Dipartimento di Chimica, via Mezzocannone 4, I-80134 Napoli, Italy
Facolt di Sci. Ambientali, Seconda Universit di Napoli, Caserta, Italy
References:
Bhatt, N.P., Patel, K., Borchardt, R.T., Chemical pathways of peptide degradation. I. Deamidation of adrenocorticotropic hormone (1990) Pharm. Res., 7, pp. 593-59
Bodanszky, M., Bodanszky, A., (1984) The Practice of Peptide Synthesis, , Berlin: Springer-Verlag
Bolton, P.D., Hydrolysis of amides. II. Substituent effect in dilute acid and alkali (1966) Aust. J. Chem., 19, pp. 1013-1021
Brennan, T.W., Clarke, S., Mechanism of cleavage at Asn 148 during the maturation of Jack bean concanavalin A (1993) Biomed. Biophys. Res. Commun., 193, pp. 1031-1037
Capasso, S., Kirby, A.J., Salvadori, S., Sica, F., Zagari, A., Kinetics and mechanism of the reversible isomerization of aspartic acid residue in tetrapeptides (1995) J. Chem. Soc. Perkin Trans., 2, pp. 437-442
Capasso, S., Mazzarella, L., Sica, F., Zagari, A., Salvadori, S., Kinetic and mechanism of succinimide ring formation in the deamidation process of asparagine residues (1993) J. Chem. Soc. Perkin Trans., 2, pp. 679-682
Capasso, S., Sica, F., Zagari, A., Identification of aminosuccinyl residues in peptides by second-derivative ultraviolet spectrometry (1987) Peptides, 8, pp. 791-796
Connors, K.A., (1990) Chemical Kinetics, the Study of Reaction Rates in Solution, pp. 245-309. , New York: VCH
Geiger, T., Clarke, S., Deamidation, isomerization, and racemization at asparaginyl and aspartyl residues in peptides (1987) J. Biol. Chem., 262, pp. 785-794
Koonin, E.V., A protein splice-junction motif in hedgehog family proteins (1995) Trends Biol. Sci., 20, pp. 141-142
Meinwald, C.Y., Stimson, E.R., Scheraga, H.A., Deamidation of the asparaginyl-glycyl sequence (1986) Int. J. Pept. Protein Res., 28, pp. 79-84
Molday, R.S., Kallen, R.G., Substituent effects on amide hydrogen exchange rates in aqueous solution (1972) J. Am. Chem. Soc., 94, pp. 6739-6745
Sondheimer, E., Holley, R.W., Imide from asparagine and glutamine (1954) J. Am. Chem. Soc., 76, pp. 2467-2470
Violand, B.N., Schlittler, M.R., Toren, P.C., Siegel, N.R., Formation of isoaspartate 99 in bovine and porcine somatotropins (1990) J. Prot. Chem., 9, pp. 109-117
Willi, A.V., Homogeneous catalysis of organic reactions (mainly acid-base) (1977) Comprehensive Chemical Kinetics, 8, pp. 1-95. , Bamford, C. H.
Tipper, C. F. H., Eds. Amsterdam: Elsevier
Bhatt, N. P., Patel, K., Borchardt, R. T., Chemical pathways of peptide degradation. I. Deamidation of adrenocorticotropic hormone (1990) Pharm. Res., 7, pp. 593-59
Bolton, P. D., Hydrolysis of amides. II. Substituent effect in dilute acid and alkali (1966) Aust. J. Chem., 19, pp. 1013-1021
Brennan, T. W., Clarke, S., Mechanism of cleavage at Asn 148 during the maturation of Jack bean concanavalin A (1993) Biomed. Biophys. Res. Commun., 193, pp. 1031-1037
Connors, K. A., (1990) Chemical Kinetics, the Study of Reaction Rates in Solution, pp. 245-309. , New York: VCH
Koonin, E. V., A protein splice-junction motif in hedgehog family proteins (1995) Trends Biol. Sci., 20, pp. 141-142
Meinwald, C. Y., Stimson, E. R., Scheraga, H. A., Deamidation of the asparaginyl-glycyl sequence (1986) Int. J. Pept. Protein Res., 28, pp. 79-84
Molday, R. S., Kallen, R. G., Substituent effects on amide hydrogen exchange rates in aqueous solution (1972) J. Am. Chem. Soc., 94, pp. 6739-6745
Violand, B. N., Schlittler, M. R., Toren, P. C., Siegel, N. R., Formation of isoaspartate 99 in bovine and porcine somatotropins (1990) J. Prot. Chem., 9, pp. 109-117
Willi, A. V., Homogeneous catalysis of organic reactions (mainly acid-base) (1977) Comprehensive Chemical Kinetics, 8, pp. 1-95. , Bamford, C. H.
Peptides (ISSN: 0196-9781, 1873-5169electronic, 0196-9781linking), 1996; 17(6): 1075-1077.
Export to BibTeX Export to EndNote
Paper type: Journal Article,
Impact factor: 1.738, 5-year impact factor: 2.372
Url: http://www.scopus.com/inward/record.url?eid=2-s2.0-0029855624&partnerID=40&md5=b9e898a230bbe70b8933cdf7d088e19e
Keywords: Asparagine, Deamidation, Peptide Bond Cleavage, Succinimide, Article, Peptide Analysis, Priority Journal, Protein Processing, Kinetics, Models, Chemical, Oligopeptides, Protein Splicing,
Affiliations:
Ctro. di Studio di B., CNR, Napoli, Italy
Facoltà di Sci. Ambientali, Seconda Università di Napoli, Caserta, Italy
Dipto. di Scienze Farmaceutiche, Università di Ferrara, Ferrara, Italy
University Chemical Laboratory, Cambridge, United Kingdom
Dipartimento di Chimica, via Mezzocannone 4, I-80134 Napoli, Italy
Facolt di Sci. Ambientali, Seconda Universit di Napoli, Caserta, Italy
References:
Bhatt, N.P., Patel, K., Borchardt, R.T., Chemical pathways of peptide degradation. I. Deamidation of adrenocorticotropic hormone (1990) Pharm. Res., 7, pp. 593-59
Bodanszky, M., Bodanszky, A., (1984) The Practice of Peptide Synthesis, , Berlin: Springer-Verlag
Bolton, P.D., Hydrolysis of amides. II. Substituent effect in dilute acid and alkali (1966) Aust. J. Chem., 19, pp. 1013-1021
Brennan, T.W., Clarke, S., Mechanism of cleavage at Asn 148 during the maturation of Jack bean concanavalin A (1993) Biomed. Biophys. Res. Commun., 193, pp. 1031-1037
Capasso, S., Kirby, A.J., Salvadori, S., Sica, F., Zagari, A., Kinetics and mechanism of the reversible isomerization of aspartic acid residue in tetrapeptides (1995) J. Chem. Soc. Perkin Trans., 2, pp. 437-442
Capasso, S., Mazzarella, L., Sica, F., Zagari, A., Salvadori, S., Kinetic and mechanism of succinimide ring formation in the deamidation process of asparagine residues (1993) J. Chem. Soc. Perkin Trans., 2, pp. 679-682
Capasso, S., Sica, F., Zagari, A., Identification of aminosuccinyl residues in peptides by second-derivative ultraviolet spectrometry (1987) Peptides, 8, pp. 791-796
Connors, K.A., (1990) Chemical Kinetics, the Study of Reaction Rates in Solution, pp. 245-309. , New York: VCH
Geiger, T., Clarke, S., Deamidation, isomerization, and racemization at asparaginyl and aspartyl residues in peptides (1987) J. Biol. Chem., 262, pp. 785-794
Koonin, E.V., A protein splice-junction motif in hedgehog family proteins (1995) Trends Biol. Sci., 20, pp. 141-142
Meinwald, C.Y., Stimson, E.R., Scheraga, H.A., Deamidation of the asparaginyl-glycyl sequence (1986) Int. J. Pept. Protein Res., 28, pp. 79-84
Molday, R.S., Kallen, R.G., Substituent effects on amide hydrogen exchange rates in aqueous solution (1972) J. Am. Chem. Soc., 94, pp. 6739-6745
Sondheimer, E., Holley, R.W., Imide from asparagine and glutamine (1954) J. Am. Chem. Soc., 76, pp. 2467-2470
Violand, B.N., Schlittler, M.R., Toren, P.C., Siegel, N.R., Formation of isoaspartate 99 in bovine and porcine somatotropins (1990) J. Prot. Chem., 9, pp. 109-117
Willi, A.V., Homogeneous catalysis of organic reactions (mainly acid-base) (1977) Comprehensive Chemical Kinetics, 8, pp. 1-95. , Bamford, C. H.
Tipper, C. F. H., Eds. Amsterdam: Elsevier
Bhatt, N. P., Patel, K., Borchardt, R. T., Chemical pathways of peptide degradation. I. Deamidation of adrenocorticotropic hormone (1990) Pharm. Res., 7, pp. 593-59
Bolton, P. D., Hydrolysis of amides. II. Substituent effect in dilute acid and alkali (1966) Aust. J. Chem., 19, pp. 1013-1021
Brennan, T. W., Clarke, S., Mechanism of cleavage at Asn 148 during the maturation of Jack bean concanavalin A (1993) Biomed. Biophys. Res. Commun., 193, pp. 1031-1037
Connors, K. A., (1990) Chemical Kinetics, the Study of Reaction Rates in Solution, pp. 245-309. , New York: VCH
Koonin, E. V., A protein splice-junction motif in hedgehog family proteins (1995) Trends Biol. Sci., 20, pp. 141-142
Meinwald, C. Y., Stimson, E. R., Scheraga, H. A., Deamidation of the asparaginyl-glycyl sequence (1986) Int. J. Pept. Protein Res., 28, pp. 79-84
Molday, R. S., Kallen, R. G., Substituent effects on amide hydrogen exchange rates in aqueous solution (1972) J. Am. Chem. Soc., 94, pp. 6739-6745
Violand, B. N., Schlittler, M. R., Toren, P. C., Siegel, N. R., Formation of isoaspartate 99 in bovine and porcine somatotropins (1990) J. Prot. Chem., 9, pp. 109-117
Willi, A. V., Homogeneous catalysis of organic reactions (mainly acid-base) (1977) Comprehensive Chemical Kinetics, 8, pp. 1-95. , Bamford, C. H.
Kinetics and mechanism of the cleavage of the peptide bond next to asparagine
The spontaneous cleavage reaction of the tetrapeptide Piv-Gly Asn-Sar-Gly-NHtBu to the C-terminal dipeptide and N-terminal succinimide dipeptide proceeds through pre-equilibrium deprotonation of the amide group of the asparagine side chain, Followed by intramolecular nucleophilic attack of nitrogen on the peptide carbonyl carbon atom. General acid-catalyzed breakdown of the intermediate then gives the products. According to this mechanism, the reaction rate strongly increases with pH and buffer concentration.
The spontaneous cleavage reaction of the tetrapeptide Piv-Gly Asn-Sar-Gly-NHtBu to the C-terminal dipeptide and N-terminal succinimide dipeptide proceeds through pre-equilibrium deprotonation of the amide group of the asparagine side chain, Followed by intramolecular nucleophilic attack of nitrogen on the peptide carbonyl carbon atom. General acid-catalyzed breakdown of the intermediate then gives the products. According to this mechanism, the reaction rate strongly increases with pH and buffer concentration.
Kinetics and mechanism of the cleavage of the peptide bond next to asparagine
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Kinetics and mechanism of the cleavage of the peptide bond next to asparagine
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Di Blasio B, Saviano M, Del Duca V, De Simone G, Rossi F, Pedone C, Benedetti E, Lorenzi GP
CONFORMATIONAL STUDIES OF HETEROCHIRAL PEPTIDES WITH DIASTEREOISOMERIC RESIDUES - CRYSTAL AND MOLECULAR-STRUCTURES OF LINEAR DIPEPTIDES DERIVED FROM LEUCINE, ISOLEUCINE, AND ALLO-ISOLEUCINE (396 views)
Biopolymers (ISSN: 0006-3525, 0006-6352, 0006-3525print), 1995 Oct; 36(4): 401-408.
Impact Factor: 2.425
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Pavone V, Lombardi A, Saviano M, Di Blasio B, Nastri F, Fattorusso R, Zaccaro L, Maglio O, Yamada T, Omote Y
Mixed conformation in C(α, α)-disubstituted tripeptides: X-ray crystal structures of Z-Aib-Dph-Gly-OMe and Bz-Dph-Dph-Gly-OMe (400 views)
Biopolymers (ISSN: 0006-3525, 0006-6352, 0006-3525print), 1994 Dec; 34(12): 1595-1604.
Impact Factor: 2.425
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Di Blasio B, Lombardi A, D'Auria G, Saviano M, Isernia C, Maglio O, Paolillo L, Pedone C, Pavone V
Beta-Alanine Containing Peptides: Gamma-Turns In Cyclotetrapeptides (560 views)
Biopolymers (ISSN: 0006-3525, 0006-6352, 0006-3525print), 1993 Apr; 31(10): 621-631.
Impact Factor: 2.425
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* The zinc - but not cadmium - containing zeta-carbonic from the diatom Thalassiosira weissflogii is potently activated by amines and amino acids (279 views)
Bioorg Chem (ISSN: 1090-2120electronic, 0045-2068linking), 2018 Oct; 80: 261-265.
Impact Factor: 3.929
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Troise AD, Buonanno M, Fiore A, Monti SM, Fogliano V
* Evolution of protein bound Maillard reaction end-products and free Amadori compounds in low lactose milk in presence of fructosamine oxidase (329 views)
Food Chem (ISSN: 0308-8146, 0308-8146print), 2016 Dec 1; 212: 722-729.
Impact Factor: 4.529
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Troise AD, Fiore A, Roviello GN, Monti SM, Fogliano V
* Simultaneous quantification of amino acids and Amadori products in foods through ion-pairing liquid chromatography-high-resolution mass spectrometry (1089 views)
Amino Acids (ISSN: 0939-4451, 1438-2199, 1438-2199electronic), 2015 Jan; 47(1): 111-124.
Impact Factor: 3.196
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Nardon C, Boscutti G, Dalla Via L, Ringhieri P, Di Noto V, Morelli G, Accardo A, Fregona D
* CCK8 peptide-labeled Pluronic® F127 micelles as a targeted vehicle of gold-based anticancer chemotherapeutics (409 views)
Medchemcomm (ISSN: 2040-2503), 2015; 6(1): 155-163.
Impact Factor: 2.319
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Accardo A, Vitiello M, Tesauro D, Galdiero M, Finamore E, Martora F, Mansi R, Ringhieri P, Morelli G
* Self-assembled or mixed peptide amphiphile micelles from herpes simplex virus glycoproteins as potential immunomodulatory treatment (474 views)
Int J Nanomed (ISSN: 1178-2013, 1176-9114, 1176-9114linking), 2014 May 7; 9(1): 2137-2148.
Impact Factor: 4.383
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Bellia F, GrassoG
* The role of copper(II) and zinc(II) in the degradation of human and murine IAPP by insulin-degrading enzyme (520 views)
J Mass Spectrom (ISSN: 1076-5174, 1096-9888), 2014; 49(4): 274-279.
Impact Factor: 2.379
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Galdiero S, Falanga A, Cantisani M, Vitiello M, Morelli G, Galdiero M
* Peptide-Lipid Interactions: Experiments and Applications (1013 views)
Int J Mol Sc (ISSN: 1422-0067, 1661-6596, 1422-0067electronic), 2013 Sep; 14(9): 18758-18789.
Impact Factor: 2.339
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Magrì A, D'Alessandro F, Di Stefano DA, Campagna T, Pappalardo G, Impellizzeri G, La Mendola D
* Copper(ii) Coordination Properties Of The Integrin Ligand Sequence Phsrn And Its New Beta-Cyclodextrin Conjugates (488 views)
Journal Of Inorganic Biochemistry, 2012 Sep; 113: 15-24.
Impact Factor: 3.444
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Merlino A, Picone D, Ercole C, Balsamo A, Sica F
* Chain termini cross-talk in the swapping process of bovine pancreatic ribonuclease (280 views)
Biochimie (ISSN: 0300-9084, 1638-6183, 1638-6183electronic), 2012 May; 94(5): 1108-1118.
Impact Factor: 3.142
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Vitiello G, Falanga A, Galdiero M, Marsh D, Galdiero S, D'Errico G
* Lipid composition modulates the interaction of peptides deriving from herpes simplex virus type I glycoproteins B and H with biomembranes (594 views)
Bba-Gen Subjects (ISSN: 0005-2736, 0006-3002, 0925-4439), 2011 Oct; 1808(10): 2517-2526.
Impact Factor: 3.99
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Pirone L, Correale S, De Paola I, Zaccaro L, De Simone G, Vitagliano L, Pedone E, Di Gaetano S
* Design, synthesis and characterization of a peptide able to bind proteins of the KCTD family: implications for KCTD - cullin 3 recognition (416 views)
J Pept Sci (ISSN: 1075-2617, 1099-1387, 1075-2617print), 2011 May; 17(5): 373-376.
Impact Factor: 1.799
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Roviello GN, Di Gaetano S, Capasso D, Franco S, Crescenzo C, Bucci EM, Pedone C
* RNA-binding and viral reverse transcriptase inhibitory activity of a novel cationic diamino acid-based peptide (478 views)
J Med Chem (ISSN: 0022-2623, 1520-4804, 0022-2623print), 2011 Apr 14; 54(7): 2095-2101.
Impact Factor: 5.248
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La Mendola D, Magrì A, Campagna T, Campitiello MA, Raiola L, Isernia C, Hansson O, Bonomo RP, Rizzarelli E
* A doppel alpha-helix peptide fragment mimics the copper(II) interactions with the whole protein (1115 views)
Chemistry (ISSN: 0947-6539, 1521-3765, 1521-3765electronic), 2010 Jun 1; 16(21): 6212-6223.
Impact Factor: 5.476
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Roviello GN, Benedetti E, Pedone C, Bucci EM
* Nucleobase-containing peptides: An overview of their characteristic features and applications (751 views)
Amino Acids (ISSN: 0939-4451, 1438-2199, 1438-2199electronic), 2010 Jun; 39(1): 45-57.
Impact Factor: 4.106
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Satriano C, Messina GM, Marino C, Aiello I, Conte E, La Mendola D, Distefano DA, D'Alessandro F, Pappalardo G, Impellizzeri G
* Surface immobilization of fibronectin-derived PHSRN peptide on functionalized polymer films - Effects on fibroblast spreading (534 views)
J Colloid Interface Sci (ISSN: 1095-7103electronic, 0021-9797linking), 2010 Jan 15; 341(2): 232-239.
Impact Factor: 3.068
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La Mendola D, Magrì A, Hansson O, Bonomo RP, Rizzarelli E
* Copper(II) complexes with peptide fragments encompassing the sequence 122-130 of human doppel protein (361 views)
Journal Of Inorganic Biochemistry, 2009 May; 103(5): 758-765.
Impact Factor: 3.444
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Vitagliano L, Esposito L, Pedone C, De Simone A
* Stability of single sheet GNNQQNY aggregates analyzed by replica exchange molecular dynamics: antiparallel versus parallel association (626 views)
Biochem Biophys Res Commun (ISSN: 1090-2104, 0006-291x, 1090-2104electronic), 2008 Dec 26; 377(4): 1036-1041.
Impact Factor: 2.648
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Dalla Serra M, Cirioni O, Vitale RM, Renzone G, Coraiola M, Giacometti A, Potrich C, Baroni E, Guella G, Sanseverino M, De Luca S, Scalise G, Amodeo P, Scaloni A
* Structural features of distinctin affecting peptide biological and biochemical properties (578 views)
Biochemistry (ISSN: 0006-2960, 1520-4995, 1520-4995electronic), 2008 Jul 29; 47(30): 7888-7899.
Impact Factor: 3.379
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Alterio V, De Simone G, Monti SM, Scozzafava A, Supuran CT
* Carbonic anhydrase inhibitors: Inhibition of human, bacterial, and archaeal isozymes with benzene-1, 3-disulfonamides-Solution and crystallographic studies (329 views)
Bioorg Med Chem Lett Bioorganic And Medicinal Chemistry Letters (ISSN: 0960-894x), 2007 Sep 1; 17(15): 4201-4207.
Impact Factor: 2.604
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D'Auria S, Varriale A, Gonnelli M, Saviano M, Staiano M, Rossi M, Strambini GB
* Tryptophan phosphorescence studies of the D-galactose/ D-glucose-binding protein from Escherichia coli provide a molecular portrait with structural and dynamics features of the protein (589 views)
J Proteome Res (ISSN: 1535-3893), 2007; 6(4): 1306-1312.
Impact Factor: 5.675
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Galdiero S, Vitiello M, D'Isanto M, Falanga A, Collins C, Raieta K, Pedone C, Browne H, Galdiero M
* Analysis of synthetic peptides from heptad-repeat domains of herpes simplex virus type 1 glycoproteins H and (618 views)
Journal Of General Virology (ISSN: 0022-1317), 2006 May; 87: 1085-1097.
Impact Factor: 3.11
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Musumeci D, Valente M, Capasso D, Palumbo R, Gorlach M, Schmidtke M, Zell R, Roviello GN, Sapio R, Pedone C, Bucci EM
* A short PNA targeting coxsackievirus B3 5′-nontranslated region prevents virus-induced cytolysis (395 views)
J Pept Sci (ISSN: 1075-2617, 1099-1387, 1075-2617print), 2006 Mar; 12(3): 161-170.
Impact Factor: 1.801
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D'Andrea LD, Del Gatto A, Pedone C, Benedetti E
* Peptide-based molecules in angiogenesis (830 views)
Chem Biol Drug Des (ISSN: 1747-0277, 1747-0285, 1747-0277linking), 2006 Feb; 67(2): 115-126.
Impact Factor: 2.507
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Roscigno P, D'Auria G, Falcigno L, D'Errico G, Paduano L
* Effect of the addition of a nonionic surfactant on the complex poly(asparagine)-cationic surfactant (360 views)
Langmuir (ISSN: 0743-7463), 2005 Sep 30; 21(18): 8123-8130.
Impact Factor: 3.705
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Saviano M, Isernia C, Bassarello C, Di Lello P, Galdiero S, Mierke DF, Benedetti E, Pedone C
* Conformational analysis by NMR and distance geometry techniques of a peptide mimetic of the third helix of the Antennapedia homeodomain (436 views)
J Pept Res (ISSN: 1397-002x), 2005 Feb; 65(2): 200-208.
Impact Factor: 1.741
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De Luca S, Morelli G
* Synthesis and characterization of a sulfated and a non-sulfated cyclic CCK8 analogue functionalized with a chelating group for metal labelling (395 views)
J Pept Sci (ISSN: 1075-2617, 1099-1387, 1075-2617print), 2004 May; 10(5): 265-273.
Impact Factor: 1.652
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Wiesehan K, Buder K, Linke RP, Patt S, Stoldt M, Unger E, Schmitt B, Bucci E, Willbold D
* Selection of D-amino-acid peptides that bind to Alzheimer's disease amyloid peptide Aβ1-42 by mirror image phage display (709 views)
Chembiochem (ISSN: 1439-4227, 1439-7633, 1439-7633electronic), 2003; 4(8): 748-753.
Impact Factor: 3.992
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Merlino A, Vitagliano L, Ceruso M, Di Nola A, Mazzarella L
* Global and local motions in ribonuclease A: A molecular dynamics study (411 views)
Biopolymers (ISSN: 0006-3525, 0006-6352, 0006-3525print), 2002 Nov 15; 65(4): 274-283.
Impact Factor: 2.372
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Grasso D, Milardi D, La Rosa C, Impellizzeri G, Pappalardo G
* The interaction of a peptide with a scrambled hydrophobic/hydrophilic sequence (Pro-Asp-Ala-Asp-Ala-His-Ala-His-Ala-His-Ala-Ala-Ala-His-Gly) (PADH) with DPPC model membranes: A DSC study (276 views)
Thermochim Acta (ISSN: 0040-6031), 2002 Jul 15; 390(1-2): 73-78.
Impact Factor: 0.974
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Improta R, Mele F, Crescenzi O, Benzi C, Barone V
* Understanding the role of stereoelectronic effects in determining collagen stability. 2. A quantum mechanical/molecular mechanical study of (Proline-Proline-Glycine)n polypeptides (340 views)
J Am Chem Soc (ISSN: 0002-7863, 0002-2786, 1520-5126), 2002 Jul 3; 124(26): 7857-7865.
Impact Factor: 6.201
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Monti SM, Gallo M, Ferracane R, Borrelli RC, Ritieni A, Greco ML, Graniti A, Fogliano V
* Analysis of bacterial lipodepsipeptides by matrix-assisted laser desorption/ionisation time-of-flight and high-performance liquid chromatography with electrospray mass spectrometry (437 views)
Rapid Commun Mass Sp (ISSN: 0951-4198, 1097-0231electronic), 2001; 15(8): 623-628.
Impact Factor: 2.478
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Orru S, Vitagliano L, Esposito L, Mazzarella L, Marino G, Ruoppolo M
Effect of deamidation on folding of ribonuclease (387 views)
Protein Sci (ISSN: 0961-8368, 1469-896xelectronic), 2000 Dec; 9(12): 2577-2582.
Impact Factor: 3.869
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Esposito L, Vitagliano L, Zagari A, Mazzarella L
Pyramidalization of backbone carbonyl carbon atoms in proteins (449 views)
Protein Sci (ISSN: 0961-8368, 1469-896xelectronic), 2000 Oct; 9(10): 2038-2042.
Impact Factor: 3.869
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Esposito L, Vitagliano L, Sica F, Sorrentino G, Zagari A, Mazzarella L
The ultrahigh resolution crystal structure of ribonuclease A containing an isoaspartyl residue: Hydration and sterochemical analysis (680 views)
J Mol Biol (ISSN: 0022-2836, 1089-8638, 1089-8638electronic), 2000 Mar 31; 297(3): 713-732.
Impact Factor: 5.388
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Martínez JC, Viguera AR, Berisio R, Wilmanns M, Mateo PL, Filimonov VV, Serrano L
Thermodynamic analysis of α-spectrin SH3 and two of its circular permutants with different loop lengths: Discerning the reasons for rapid folding in proteins (378 views)
Biochemistry (ISSN: 0006-2960, 1520-4995, 1520-4995electronic), 1999 Jan 12; 38(2): 549-559.
Impact Factor: 4.493
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Fonti R, Cheung N-KV, Bridger GJ, Guo H-F, Abrams MJ, Larson SM
99mTc-monoclonal antibody radiolabeled via hydrazino nicotinamide derivative for imaging disialoganglioside G(D2)-positive tumors (373 views)
Nucl Med Biol (ISSN: 0969-8051, 0883-2897), 1999; 26(6): 681-686.
Impact Factor: 1.623
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Arena G, Conato C, Contino A, Pulidori F, Purrello R, Remelli M, Tabbì G
Cu(II)-L-glutamine and L-asparagine binary complexes. A thermodynamic and spectroscopic study (320 views)
Ann Chim (ISSN: 0003-4592), 1998 Jan; 88(1-2): 1-12.
Impact Factor: 0.811
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Capasso S, Di Donato A, Esposito L, Sica F, Sorrentino G, Vitagliano L, Zagari A, Mazzarella L
Deamidation in proteins: The crystal structure of bovine pancreatic ribonuclease with an isoaspartyl residue at position 67 (481 views)
J Mol Biol (ISSN: 0022-2836, 1089-8638, 1089-8638electronic), 1996; 257(3): 492-496.
Impact Factor: 5.673
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Saviano M, Rossi F, Filizola M, Isernia C, Di Blasio B, Benedetti E, Pedone C, Siemion IZ, Pedyczak A
Bioactive peptides: conformational studies of [Tyr4] cyclolinopeptide (406 views)
Biopolymers (ISSN: 0006-3525print, 0006-3525linking, 1097-0282electronic), 1995 Oct; 26(12): 453-460.
Impact Factor: 2.572
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Di Blasio B, Saviano M, Del Duca V, De Simone G, Rossi F, Pedone C, Benedetti E, Lorenzi GP
CONFORMATIONAL STUDIES OF HETEROCHIRAL PEPTIDES WITH DIASTEREOISOMERIC RESIDUES - CRYSTAL AND MOLECULAR-STRUCTURES OF LINEAR DIPEPTIDES DERIVED FROM LEUCINE, ISOLEUCINE, AND ALLO-ISOLEUCINE (396 views)
Biopolymers (ISSN: 0006-3525, 0006-6352, 0006-3525print), 1995 Oct; 36(4): 401-408.
Impact Factor: 2.425
View Export to BibTeX Export to EndNote
Pavone V, Lombardi A, Saviano M, Di Blasio B, Nastri F, Fattorusso R, Zaccaro L, Maglio O, Yamada T, Omote Y
Mixed conformation in C(α, α)-disubstituted tripeptides: X-ray crystal structures of Z-Aib-Dph-Gly-OMe and Bz-Dph-Dph-Gly-OMe (400 views)
Biopolymers (ISSN: 0006-3525, 0006-6352, 0006-3525print), 1994 Dec; 34(12): 1595-1604.
Impact Factor: 2.425
View Export to BibTeX Export to EndNote
Di Blasio B, Lombardi A, D'Auria G, Saviano M, Isernia C, Maglio O, Paolillo L, Pedone C, Pavone V
Beta-Alanine Containing Peptides: Gamma-Turns In Cyclotetrapeptides (560 views)
Biopolymers (ISSN: 0006-3525, 0006-6352, 0006-3525print), 1993 Apr; 31(10): 621-631.
Impact Factor: 2.425
View Export to BibTeX Export to EndNote
42 Records (42 excluding Abstracts).
Total impact factor: 137.203 (137.203 excluding Abstracts).
Total 5 year impact factor: 140.524 (140.524 excluding Abstracts).
Total impact factor: 137.203 (137.203 excluding Abstracts).
Total 5 year impact factor: 140.524 (140.524 excluding Abstracts).
362 views. Last view on Saturday 14 January 2023, 17:43:45
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