CCK8 peptide-labeled Pluronic® F127 micelles as a targeted vehicle of gold-based anticancer chemotherapeutics(409 views) Nardon C, Boscutti G, Dalla Via L, Ringhieri P, Di Noto V, Morelli G, Accardo A, Fregona D
Keywords: Cholecystokinin Octapeptide, Cisplatin, Dibromo[ethyl N (dithiocarboxy) N Methylglycinato]gold, Gold Complex, Phosphate Buffered Saline, Poloxamer, Sodium Chloride, Unclassified Drug, Antineoplastic Activity, Aqueous Solution, Article, Cell Proliferation, Concentration Response, Controlled Study, Dialysis Membrane, Drug Cytotoxicity, Drug Delivery System, Drug Determination, Drug Formulation, Drug Potency, Drug Protein Binding, Drug Purification, Drug Selectivity, Drug Solubility, Drug Stability, Drug Synthesis, Drug Targeting, Fluorescence Spectroscopy, Genetic Transfection, Human, Human Cell, Hydrophilicity, In Vitro Study, Lipophilicity, Mathematical Computing, Mathematical Model, Micelle, Micellization, Nanoencapsulation, Oxidation, Peptide Analysis, Peptide Synthesis, Timed Drug Release, Dibromo [ethyl N (dithiocarboxy) N Methylglycinato] Gold,
Affiliations: *** IBB - CNR ***
University of Padova, Department of Chemical Sciences, Via Marzolo 1Padova, Italy
University of Naples Federico II, Department of Pharmacy, CIRPeB and IBB CNR, Via Mezzocannone 16Naples, Italy
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Nagy, E. M., Nardon, C., Giovagnini, L., Marchi, L., Trevisan, A., Fregona, D., Promising anticancer mono- and dinuclear ruthenium (iii) dithiocarbamato complexes: Systematic solution studies (2011) Dalton Trans., 40, pp. 11885-11895
Hincal, A. A., Long, D. F., Repta, A. J., Cis-platin stability in aqueous parenteral vehicles (1979) J. Parenter. Drug Assoc., 33, pp. 107-116
Lafollette, J. M., Arbus, M. H., Lauper, R. D., Stability of cisplatin admixtures in polyvinyl chloride bags (1985) Am. J. Hosp. Pharm., 42, p. 2652
Riley, C. M., Sternson, L. A., Cisplatin (1985) Anal. Profiles Drug Subst. Excipients, 14, pp. 77-105
Chiappetta, D. A., Sosnik, A., Poly (ethylene oxide) -poly (propylene oxide) block copolymer micelles as drug delivery agents: Improved hydrosolubility, stability and bioavailability of drugs (2007) Eur. J. Pharm. Biopharm., 66, pp. 303-317
Grindel, J. M., Jaworski, T., Piraner, O., Emanuele, R. M., Balasubramanian, M., Distribution, metabolism, and excretion of a novel surface-active agent, purified poloxamer 188, in rats, dogs, and humans (2002) J. Pharm. Sci., 91, pp. 1936-1947
Reubi, J. C., Schaer, J., Waser, B., Cholecystokinin (CCK) -A and CCK-B/gastrin receptors in human tumors (1997) Cancer Res., 57, pp. 1377-1386
Wank, S. A., Pisegna, J. R., De Weerth, A., Brain and gastrointestinal cholecystokinin receptor family: Structure and functional expression (1992) Proc. Natl. Acad. Sci. U. S. A., 89, pp. 8691-8695
Wank, S. A., G protein-coupled receptors in gastrointestinal physiology I. CCK receptors: An exemplary family (1998) Am. J. Physiol., 274, pp. G607-G613
Reubi, J. C., Peptide receptors as molecular targets for cancer diagnosis and therapy (2003) Endocr. Rev., 24, pp. 389-427
Reubi, J. C., Waser, B., Concomitant expression of several peptide receptors in neuroendocrine tumours: Molecular basis for in vivo multireceptor tumour targeting (2003) Eur. J. Nucl. Med. Mol. Imaging, 30, pp. 781-793
Pace, C. N., Vajdos, F., Fee, L., Grimsley, G., Gray, T., How to measure and predict the molar absorption coefficient of a protein (1995) Protein Sci., 4, pp. 2411-2423
Aloj, L., Carac, C., Panico, M., Zannetti, A., Del Vecchio, S., Tesauro, D., De Luca, S., Salvatore, M., In vitro and in vivo evaluation of 111In-DTPAGlu-G-CCK8 for cholecystokinin-b receptor imaging (2004) J. Nucl. Med., 45, pp. 485-494
Sharma, P. K., Bhatia, S. R., Effect of anti-inflammatories on Pluronic F127: Micellar assembly, gelation and partitioning (2004) Int. J. Pharm., 278, pp. 361-377
Franchini, G. C., Giusti, A., Preti, C., Tassi, L., Zannini, P., Coordinating ability of methylpiperidine dithiocarbamates towards platinum group metals (1985) Polyhedron, 4, pp. 1553-1558
Hadjikostas, C. C., Katsoulos, G. A., Shakhatreh, S. K., Synthesis and spectral studies of some new palladium (II) and platinum (II) dithiocarbimato complexes. Reactions of bases with the corresponding N-alkyldithiocarbamates (1987) Inorg. Chim. Acta, 133, pp. 129-132
Roettger, B. F., Rentsch, R. U., Pinon, D., Holicky, E., Hadac, E., Larkin, J. M., Miller, L. J., Dual pathways of internalization of the cholecystokinin receptor (1995) J. Cell Biol., 128, pp. 1029-1041
Kouodom, M. N., Ronconi, L., Celegato, M., Nardon, C., Marchi, L., Dou, Q. P., Aldinucci, D., Fregona, D., Toward the selective delivery of chemotherapeutics into tumor cells by targeting peptide transporters: Tailored gold-based anticancer peptidomimetics (2012) J. Med. Chem., 55, pp. 2212-2226
CCK8 peptide-labeled Pluronic® F127 micelles as a targeted vehicle of gold-based anticancer chemotherapeutics