Haptoglobin binds the antiatherogenic protein apolipoprotein e - Impairment of apolipoprotein e stimulation of both lecithin: Cholesterol acyltransferase activity and cholesterol uptake by hepatocytes (398 views)
Febs J (ISSN: 1742-464x), 2009 Nov; 276(21): 6158-6171.
Export to BibTeX Export to EndNote
Paper type: Journal Article,
Impact factor: 3.042, 5-year impact factor: 3.276
Url: http://www.scopus.com/inward/record.url?eid=2-s2.0-70349948952&partnerID=40&md5=0c95d2c694a99f5c1961e85f72dfc7ba
Keywords: Apolipoprotein A-I, Haptoglobin, High-Density Lipoprotein (hdl), Lecithin:Cholesterol Acyltransferase (lcat), Low Density Lipoprotein, Phosphatidylcholine Sterol Acyltransferase, Protein Subunit, Very Low Density Lipoprotein, Article, Atherosclerosis, Binding Affinity, Cholesterol Esterification, Cholesterol Transport, Controlled Study, Electrophoresis, Enzyme Activation, Enzyme Activity, Enzyme Linked Immunosorbent Assay, Human, Human Cell, Human Tissue, Immunoblotting, Inflammation, Liver Cell, Molecular Interaction, Nucleotide Sequence, Priority Journal, Protein Protein Interaction, Western Blotting, Apolipoproteins E, Competitive, Cell Line, Tumor, Hemoglobins, Hepatocytes, Vldl, Phosphatidylcholine-Sterol O-Acyltransferase, Lecithin: Cholesterol Acyltransferase (lcat),
Affiliations:
*** IBB - CNR ***
Dipartimento Delle Scienze Biologiche, Università di Napoli Federico II, via Mezzocannone 8, 80134 Napoli, Italy
Istituto per Il Sistema Produzione Animale in Ambiente Mediterraneo, Consiglio Nazionale Delle Ricerche, Napoli, Italy
Istituto di Biostrutture e Bioimmagini, Consiglio Nazionale Delle Ricerche, Napoli, Italy
References:
Libby, P., Ridker, P.M., Maseri, A., Inflammation and atherosclerosis (2002) Circulation, 105, pp. 1135-114
Libby, P., Inflammatory mechanisms: The molecular basis of inflammation and disease (2007) Nutr Rev, 65, pp. 140-146
Kontush, A., Chapman, M.J., Functionally defective high-density lipoprotein: A new therapeutic target at the crossroads of dyslipidemia, inflammation, and atherosclerosis (2006) Pharmacol Rev, 58, pp. 342-374
Rader, D.J., Molecular regulation of HDL metabolism and function: Implications for novel therapies (2006) J Clin Invest, 116, pp. 3090-3100
Rader, D.J., Alexander, E.T., Weibel, G.L., Billheimer, J., Rothblat, G.H., Role of reverse cholesterol transport in animals and humans and relationship to atherosclerosis (2009) J Lipid Res, 50, pp. 189-194
Spagnuolo, M.S., Cigliano, L., D'Andrea, L.D., Pedone, C., Abrescia, P., Assignment of the binding site for haptoglobin on apolipoprotein A-I (2005) J Biol Chem, 280, pp. 1193-1198
Porta, A., Cassano, E., Balestrieri, M., Bianco, M., Picone, R., De Stefano, C., Abrescia, P., Haptoglobin transport into human ovarian follicles and its binding to apolipoprotein A-I (1999) Zygote, 7, pp. 67-77
Kunitake, S.T., Carilli, C.T., Lau, K., Protter, A.A., Naya-Vigne, J., Kane, J.P., Identification of proteins associated with apolipoprotein A-I-containing lipoproteins purified by selected-affinity immunosorption (1994) Biochemistry, 33, pp. 1988-1993
Chapelle, J.P., Albert, A., Smeets, J.P., Heusghem, C., Kulbertus, H.E., Effect of the haptoglobin phenotype on the size of a myocardial infarct (1982) N Engl J Med, 307, pp. 457-463
Delanghe, J., Cambier, B., Langlois, M., De Buyzere, M., Neels, H., De Bacquer, D., Van Cauwelaert, P., Haptoglobin polymorphism, a genetic risk factor in coronary artery bypass surgery (1997) Atherosclerosis, 132, pp. 215-219
Giblett, E., Haptoglobin (1974) Structure and Function of Plasma Proteins, pp. 55-72. , In. Allison, A.C. ed. pp. Plenum Press. New York
Langlois, M.R., Delanghe, J.R., Biological and clinical significance of haptoglobin polymorphism in humans (1996) Clin Chem, 42, pp. 1589-1600
Balestrieri, M., Cigliano, L., De Simone, M.L., Dale, B., Abrescia, P., Haptoglobin inhibits lecithin-cholesterol acyltransferase in human ovarian follicular fluid (2001) Mol Reprod Dev, 59, pp. 186-191
Cigliano, L., Spagnuolo, M.S., Dale, B., Balestrieri, M., Abrescia, P., Estradiol esterification in the human preovulatory follicle (2001) Steroids, 66, pp. 889-896
Salvatore, A., Cigliano, L., Bucci, E.M., Corpillo, D., Velasco, S., Carlucci, A., Pedone, C., Abrescia, P., Haptoglobin binding to apolipoprotein A-I prevents damage from hydroxyl radicals on its stimulatory activity of the enzyme lecithin-cholesterol acyl-transferase (2007) Biochemistry, 46, pp. 11158-11168
Braeckman, L., De Bacquer, D., Delanghe, J., Claeys, L., De Backer, G., Associations between haptoglobin polymorphism, lipids, lipoproteins and inflammatory variables (1999) Atherosclerosis, 143, pp. 383-388
De Bacquer, D., De Backer, G., Langlois, M., Delanghe, J., Kesteloot, H., Kornitzer, M., Haptoglobin polymorphism as a risk factor for coronary heart disease mortality (2001) Atherosclerosis, 157, pp. 161-166
Matuszek, M.A., Aristoteli, L.P., Bannon, P.G., Hendel, P.N., Hughes, C.F., Jessup, W., Dean, R.T., Kritharides, L., Haptoglobin elutes from human atherosclerotic coronary arteries - A potential marker of arterial pathology (2003) Atherosclerosis, 168, pp. 389-396
Greenow, K., Pearce, N.J., Ramji, D.P., The key role of apolipoprotein e in atherosclerosis (2005) J Mol Med, 83, pp. 329-342
Curtiss, L.K., Boisvert, W.A., Apolipoprotein e and atherosclerosis (2000) Curr Opin Lipidol, 11, pp. 243-251
Curtiss, L.K., Valenta, D.T., Hime, N.J., Rye, K.A., What is so special about apolipoprotein AI in reverse cholesterol transport? (2006) Arterioscler Thromb Vasc Biol, 26, pp. 12-19
Zhao, Y., Thorngate, F.E., Weisgraber, K.H., Williams, D.L., Parks, J.S., Apolipoprotein e is the major physiological activator of lecithin-cholesterol acyltransferase (LCAT) on apolipoprotein B lipoproteins (2005) Biochemistry, 44, pp. 1013-1025
Mahley, R.W., Rall, S.C., Apolipoprotein E: Far more than a lipid transport protein (2000) Annu Rev Genomics Hum Genet, 1, pp. 507-537
Rademacher, B.E., Steele, W.J., A general method for the isolation of haptoglobin 1-1, 1-2 and 2-2 from human plasma (1987) Anal Biochem, 160, pp. 119-126
Schumaker, V.N., Puppione, D.L., Sequential flotation ultracentrifugation (1986) Methods in Enzymology, pp. 155-170. , In. Segrest, J.P. Albers, J.J. eds. pp. Academic Press. Orlando, Florida
Shiflett, A.M., Bishop, J.R., Pahwa, A., Hajduk, S.L., Human high density lipoproteins are platforms for assembly of multi-component innate immune complexes (2005) J Biol Chem, 280, pp. 32578-32585
Karlsson, H., Leanderson, P., Tagesson, C., Lindahl, M., Lipoproteomics I: Mapping of proteins in low-density lipoprotein using two-dimensional gel electrophoresis and mass spectrometry (2005) Proteomics, 5 (2), pp. 551-565. , DOI 10.1002/pmic.200300938
Xu, S., Laccotripe, M., Huang, X., Rigotti, A., Zannis, V.I., Krieger, M., Apolipoproteins of HDL can directly mediate binding to the scavenger receptor SR-BI, an HDL receptor that mediates selective lipid uptake (1997) J Lipid Res, 38, pp. 1289-1298
Scanu, A.M., Edelstein, C., HDL: Bridging past and present with a look at the future (2008) FASEB J, 22, pp. 4044-4054
Kim, W.S., Rahmanto, A.S., Kamili, A., Rye, K.-A., Guillemin, G.J., Gelissen, I.C., Jessup, W., Garner, B., Role of ABCG1 and ABCA1 in regulation of neuronal cholesterol efflux to apolipoprotein e discs and suppression of amyloid-β peptide generation (2007) J Biol Chem, 282, pp. 2851-2861
Hirsch-Reinshagen, V., Wellington, C.L., Cholesterol metabolism, apolipoprotein E, adenosine triphosphate-binding cassette transporters, and Alzheimer's disease (2007) Curr Opin Lipidol, 18, pp. 325-332
Yang, D.S., Small, D.H., Seydel, U., Smith, J.D., Hallmayer, J., Gandy, S.E., Martins, R.N., Apolipoprotein e promotes the binding and uptake of beta-amyloid into Chinese hamster ovary cells in an isoform-specific manner (1999) Neuroscience, 90, pp. 1217-1226
Koistinaho, M., Lin, S., Wu, X., Esterman, M., Koger, D., Hanson, J., Higgs, R., Bales, K.R., Apolipoprotein e promotes astrocyte colocalization and degradation of deposited amyloid-beta peptides (2004) Nat Med, 10, pp. 719-726
Sadowski, M., Pankiewicz, J., Scholtzova, H., Ripellino, J.A., Li, Y., Schmidt, S.D., Mathews, P.M., Sigurdsson, E.M., A synthetic peptide blocking the apolipoprotein E/beta-amyloid binding mitigates beta-amyloid toxicity and fibril formation in vitro and reduces beta-amyloid plaques in transgenic mice (2004) Am J Pathol, 165, pp. 937-948
Sanchez, D.J., Armstrong, L., Aguilar, R., Adrian, G.S., Haro, L., Martinez, A.O., Haptoglobin gene expression in human glioblastoma cell lines (2001) Neurosci Lett, 303, pp. 181-184
Lee, M.Y., Kim, S.Y., Choi, J.S., Lee, I.H., Choi, Y.S., Jin, J.Y., Park, S.J., Kim, I.S., Upregulation of haptoglobin in reactive astrocytes after transient forebrain ischemia in rats (2002) J Cereb Blood Flow Metab, 22, pp. 1176-1180
Chen, C.-H., Albers, J.J., Characterization of proteoliposomes containing apoprotein A-I: A new substrate for the measurement of lecithin:cholesterol acyltransferase activity (1982) J Lipid Res, 23, pp. 680-691
Sparks, D.L., Phillips, M.C., Lund-Katz, S., The conformation of apolipoprotein A-I in discoidal and spherical recombinant high density lipoprotein particles (1992) J Biol Chem, 267, pp. 25830-25838
Garcia, A., Barbaras, R., Collet, X., Bogyo, A., Chap, H., Perret, B., High-density lipoprotein 3 receptor-dependent endocytosis pathway in a human hepatoma cell line (HepG2) (1996) Biochemistry, 35, pp. 13064-13071
Bradford, M.M., A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding (1976) Anal Biochem, 72, pp. 248-252
Matz, C.E., Jonas, A., Micellar complexes of human apolipoprotein A-I with phosphatidylcholines and cholesterol prepared from cholate-lipid dispersions (1982) J Biol Chem, 257, pp. 4535-4540
Rader, D. J., Molecular regulation of HDL metabolism and function: Implications for novel therapies (2006) J Clin Invest, 116, pp. 3090-3100
Rader, D. J., Alexander, E. T., Weibel, G. L., Billheimer, J., Rothblat, G. H., Role of reverse cholesterol transport in animals and humans and relationship to atherosclerosis (2009) J Lipid Res, 50, pp. 189-194
Spagnuolo, M. S., Cigliano, L., D'Andrea, L. D., Pedone, C., Abrescia, P., Assignment of the binding site for haptoglobin on apolipoprotein A-I (2005) J Biol Chem, 280, pp. 1193-1198
Kunitake, S. T., Carilli, C. T., Lau, K., Protter, A. A., Naya-Vigne, J., Kane, J. P., Identification of proteins associated with apolipoprotein A-I-containing lipoproteins purified by selected-affinity immunosorption (1994) Biochemistry, 33, pp. 1988-1993
Chapelle, J. P., Albert, A., Smeets, J. P., Heusghem, C., Kulbertus, H. E., Effect of the haptoglobin phenotype on the size of a myocardial infarct (1982) N Engl J Med, 307, pp. 457-463
Langlois, M. R., Delanghe, J. R., Biological and clinical significance of haptoglobin polymorphism in humans (1996) Clin Chem, 42, pp. 1589-1600
Matuszek, M. A., Aristoteli, L. P., Bannon, P. G., Hendel, P. N., Hughes, C. F., Jessup, W., Dean, R. T., Kritharides, L., Haptoglobin elutes from human atherosclerotic coronary arteries - A potential marker of arterial pathology (2003) Atherosclerosis, 168, pp. 389-396
Curtiss, L. K., Boisvert, W. A., Apolipoprotein e and atherosclerosis (2000) Curr Opin Lipidol, 11, pp. 243-251
Curtiss, L. K., Valenta, D. T., Hime, N. J., Rye, K. A., What is so special about apolipoprotein AI in reverse cholesterol transport? (2006) Arterioscler Thromb Vasc Biol, 26, pp. 12-19
Mahley, R. W., Rall, S. C., Apolipoprotein E: Far more than a lipid transport protein (2000) Annu Rev Genomics Hum Genet, 1, pp. 507-537
Rademacher, B. E., Steele, W. J., A general method for the isolation of haptoglobin 1-1, 1-2 and 2-2 from human plasma (1987) Anal Biochem, 160, pp. 119-126
Schumaker, V. N., Puppione, D. L., Sequential flotation ultracentrifugation (1986) Methods in Enzymology, pp. 155-170. , In. Segrest, J. P. Albers, J. J. eds. pp. Academic Press. Orlando, Florida
Shiflett, A. M., Bishop, J. R., Pahwa, A., Hajduk, S. L., Human high density lipoproteins are platforms for assembly of multi-component innate immune complexes (2005) J Biol Chem, 280, pp. 32578-32585
Scanu, A. M., Edelstein, C., HDL: Bridging past and present with a look at the future (2008) FASEB J, 22, pp. 4044-4054
Kim, W. S., Rahmanto, A. S., Kamili, A., Rye, K. -A., Guillemin, G. J., Gelissen, I. C., Jessup, W., Garner, B., Role of ABCG1 and ABCA1 in regulation of neuronal cholesterol efflux to apolipoprotein e discs and suppression of amyloid- peptide generation (2007) J Biol Chem, 282, pp. 2851-2861
Yang, D. S., Small, D. H., Seydel, U., Smith, J. D., Hallmayer, J., Gandy, S. E., Martins, R. N., Apolipoprotein e promotes the binding and uptake of beta-amyloid into Chinese hamster ovary cells in an isoform-specific manner (1999) Neuroscience, 90, pp. 1217-1226
Sanchez, D. J., Armstrong, L., Aguilar, R., Adrian, G. S., Haro, L., Martinez, A. O., Haptoglobin gene expression in human glioblastoma cell lines (2001) Neurosci Lett, 303, pp. 181-184
Lee, M. Y., Kim, S. Y., Choi, J. S., Lee, I. H., Choi, Y. S., Jin, J. Y., Park, S. J., Kim, I. S., Upregulation of haptoglobin in reactive astrocytes after transient forebrain ischemia in rats (2002) J Cereb Blood Flow Metab, 22, pp. 1176-1180
Chen, C. -H., Albers, J. J., Characterization of proteoliposomes containing apoprotein A-I: A new substrate for the measurement of lecithin: cholesterol acyltransferase activity (1982) J Lipid Res, 23, pp. 680-691
Sparks, D. L., Phillips, M. C., Lund-Katz, S., The conformation of apolipoprotein A-I in discoidal and spherical recombinant high density lipoprotein particles (1992) J Biol Chem, 267, pp. 25830-25838
Bradford, M. M., A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding (1976) Anal Biochem, 72, pp. 248-252
Matz, C. E., Jonas, A., Micellar complexes of human apolipoprotein A-I with phosphatidylcholines and cholesterol prepared from cholate-lipid dispersions (1982) J Biol Chem, 257, pp. 4535-4540
Febs J (ISSN: 1742-464x), 2009 Nov; 276(21): 6158-6171.
Export to BibTeX Export to EndNote
Paper type: Journal Article,
Impact factor: 3.042, 5-year impact factor: 3.276
Url: http://www.scopus.com/inward/record.url?eid=2-s2.0-70349948952&partnerID=40&md5=0c95d2c694a99f5c1961e85f72dfc7ba
Keywords: Apolipoprotein A-I, Haptoglobin, High-Density Lipoprotein (hdl), Lecithin:Cholesterol Acyltransferase (lcat), Low Density Lipoprotein, Phosphatidylcholine Sterol Acyltransferase, Protein Subunit, Very Low Density Lipoprotein, Article, Atherosclerosis, Binding Affinity, Cholesterol Esterification, Cholesterol Transport, Controlled Study, Electrophoresis, Enzyme Activation, Enzyme Activity, Enzyme Linked Immunosorbent Assay, Human, Human Cell, Human Tissue, Immunoblotting, Inflammation, Liver Cell, Molecular Interaction, Nucleotide Sequence, Priority Journal, Protein Protein Interaction, Western Blotting, Apolipoproteins E, Competitive, Cell Line, Tumor, Hemoglobins, Hepatocytes, Vldl, Phosphatidylcholine-Sterol O-Acyltransferase, Lecithin: Cholesterol Acyltransferase (lcat),
Affiliations:
*** IBB - CNR ***
Dipartimento Delle Scienze Biologiche, Università di Napoli Federico II, via Mezzocannone 8, 80134 Napoli, Italy
Istituto per Il Sistema Produzione Animale in Ambiente Mediterraneo, Consiglio Nazionale Delle Ricerche, Napoli, Italy
Istituto di Biostrutture e Bioimmagini, Consiglio Nazionale Delle Ricerche, Napoli, Italy
References:
Libby, P., Ridker, P.M., Maseri, A., Inflammation and atherosclerosis (2002) Circulation, 105, pp. 1135-114
Libby, P., Inflammatory mechanisms: The molecular basis of inflammation and disease (2007) Nutr Rev, 65, pp. 140-146
Kontush, A., Chapman, M.J., Functionally defective high-density lipoprotein: A new therapeutic target at the crossroads of dyslipidemia, inflammation, and atherosclerosis (2006) Pharmacol Rev, 58, pp. 342-374
Rader, D.J., Molecular regulation of HDL metabolism and function: Implications for novel therapies (2006) J Clin Invest, 116, pp. 3090-3100
Rader, D.J., Alexander, E.T., Weibel, G.L., Billheimer, J., Rothblat, G.H., Role of reverse cholesterol transport in animals and humans and relationship to atherosclerosis (2009) J Lipid Res, 50, pp. 189-194
Spagnuolo, M.S., Cigliano, L., D'Andrea, L.D., Pedone, C., Abrescia, P., Assignment of the binding site for haptoglobin on apolipoprotein A-I (2005) J Biol Chem, 280, pp. 1193-1198
Porta, A., Cassano, E., Balestrieri, M., Bianco, M., Picone, R., De Stefano, C., Abrescia, P., Haptoglobin transport into human ovarian follicles and its binding to apolipoprotein A-I (1999) Zygote, 7, pp. 67-77
Kunitake, S.T., Carilli, C.T., Lau, K., Protter, A.A., Naya-Vigne, J., Kane, J.P., Identification of proteins associated with apolipoprotein A-I-containing lipoproteins purified by selected-affinity immunosorption (1994) Biochemistry, 33, pp. 1988-1993
Chapelle, J.P., Albert, A., Smeets, J.P., Heusghem, C., Kulbertus, H.E., Effect of the haptoglobin phenotype on the size of a myocardial infarct (1982) N Engl J Med, 307, pp. 457-463
Delanghe, J., Cambier, B., Langlois, M., De Buyzere, M., Neels, H., De Bacquer, D., Van Cauwelaert, P., Haptoglobin polymorphism, a genetic risk factor in coronary artery bypass surgery (1997) Atherosclerosis, 132, pp. 215-219
Giblett, E., Haptoglobin (1974) Structure and Function of Plasma Proteins, pp. 55-72. , In. Allison, A.C. ed. pp. Plenum Press. New York
Langlois, M.R., Delanghe, J.R., Biological and clinical significance of haptoglobin polymorphism in humans (1996) Clin Chem, 42, pp. 1589-1600
Balestrieri, M., Cigliano, L., De Simone, M.L., Dale, B., Abrescia, P., Haptoglobin inhibits lecithin-cholesterol acyltransferase in human ovarian follicular fluid (2001) Mol Reprod Dev, 59, pp. 186-191
Cigliano, L., Spagnuolo, M.S., Dale, B., Balestrieri, M., Abrescia, P., Estradiol esterification in the human preovulatory follicle (2001) Steroids, 66, pp. 889-896
Salvatore, A., Cigliano, L., Bucci, E.M., Corpillo, D., Velasco, S., Carlucci, A., Pedone, C., Abrescia, P., Haptoglobin binding to apolipoprotein A-I prevents damage from hydroxyl radicals on its stimulatory activity of the enzyme lecithin-cholesterol acyl-transferase (2007) Biochemistry, 46, pp. 11158-11168
Braeckman, L., De Bacquer, D., Delanghe, J., Claeys, L., De Backer, G., Associations between haptoglobin polymorphism, lipids, lipoproteins and inflammatory variables (1999) Atherosclerosis, 143, pp. 383-388
De Bacquer, D., De Backer, G., Langlois, M., Delanghe, J., Kesteloot, H., Kornitzer, M., Haptoglobin polymorphism as a risk factor for coronary heart disease mortality (2001) Atherosclerosis, 157, pp. 161-166
Matuszek, M.A., Aristoteli, L.P., Bannon, P.G., Hendel, P.N., Hughes, C.F., Jessup, W., Dean, R.T., Kritharides, L., Haptoglobin elutes from human atherosclerotic coronary arteries - A potential marker of arterial pathology (2003) Atherosclerosis, 168, pp. 389-396
Greenow, K., Pearce, N.J., Ramji, D.P., The key role of apolipoprotein e in atherosclerosis (2005) J Mol Med, 83, pp. 329-342
Curtiss, L.K., Boisvert, W.A., Apolipoprotein e and atherosclerosis (2000) Curr Opin Lipidol, 11, pp. 243-251
Curtiss, L.K., Valenta, D.T., Hime, N.J., Rye, K.A., What is so special about apolipoprotein AI in reverse cholesterol transport? (2006) Arterioscler Thromb Vasc Biol, 26, pp. 12-19
Zhao, Y., Thorngate, F.E., Weisgraber, K.H., Williams, D.L., Parks, J.S., Apolipoprotein e is the major physiological activator of lecithin-cholesterol acyltransferase (LCAT) on apolipoprotein B lipoproteins (2005) Biochemistry, 44, pp. 1013-1025
Mahley, R.W., Rall, S.C., Apolipoprotein E: Far more than a lipid transport protein (2000) Annu Rev Genomics Hum Genet, 1, pp. 507-537
Rademacher, B.E., Steele, W.J., A general method for the isolation of haptoglobin 1-1, 1-2 and 2-2 from human plasma (1987) Anal Biochem, 160, pp. 119-126
Schumaker, V.N., Puppione, D.L., Sequential flotation ultracentrifugation (1986) Methods in Enzymology, pp. 155-170. , In. Segrest, J.P. Albers, J.J. eds. pp. Academic Press. Orlando, Florida
Shiflett, A.M., Bishop, J.R., Pahwa, A., Hajduk, S.L., Human high density lipoproteins are platforms for assembly of multi-component innate immune complexes (2005) J Biol Chem, 280, pp. 32578-32585
Karlsson, H., Leanderson, P., Tagesson, C., Lindahl, M., Lipoproteomics I: Mapping of proteins in low-density lipoprotein using two-dimensional gel electrophoresis and mass spectrometry (2005) Proteomics, 5 (2), pp. 551-565. , DOI 10.1002/pmic.200300938
Xu, S., Laccotripe, M., Huang, X., Rigotti, A., Zannis, V.I., Krieger, M., Apolipoproteins of HDL can directly mediate binding to the scavenger receptor SR-BI, an HDL receptor that mediates selective lipid uptake (1997) J Lipid Res, 38, pp. 1289-1298
Scanu, A.M., Edelstein, C., HDL: Bridging past and present with a look at the future (2008) FASEB J, 22, pp. 4044-4054
Kim, W.S., Rahmanto, A.S., Kamili, A., Rye, K.-A., Guillemin, G.J., Gelissen, I.C., Jessup, W., Garner, B., Role of ABCG1 and ABCA1 in regulation of neuronal cholesterol efflux to apolipoprotein e discs and suppression of amyloid-β peptide generation (2007) J Biol Chem, 282, pp. 2851-2861
Hirsch-Reinshagen, V., Wellington, C.L., Cholesterol metabolism, apolipoprotein E, adenosine triphosphate-binding cassette transporters, and Alzheimer's disease (2007) Curr Opin Lipidol, 18, pp. 325-332
Yang, D.S., Small, D.H., Seydel, U., Smith, J.D., Hallmayer, J., Gandy, S.E., Martins, R.N., Apolipoprotein e promotes the binding and uptake of beta-amyloid into Chinese hamster ovary cells in an isoform-specific manner (1999) Neuroscience, 90, pp. 1217-1226
Koistinaho, M., Lin, S., Wu, X., Esterman, M., Koger, D., Hanson, J., Higgs, R., Bales, K.R., Apolipoprotein e promotes astrocyte colocalization and degradation of deposited amyloid-beta peptides (2004) Nat Med, 10, pp. 719-726
Sadowski, M., Pankiewicz, J., Scholtzova, H., Ripellino, J.A., Li, Y., Schmidt, S.D., Mathews, P.M., Sigurdsson, E.M., A synthetic peptide blocking the apolipoprotein E/beta-amyloid binding mitigates beta-amyloid toxicity and fibril formation in vitro and reduces beta-amyloid plaques in transgenic mice (2004) Am J Pathol, 165, pp. 937-948
Sanchez, D.J., Armstrong, L., Aguilar, R., Adrian, G.S., Haro, L., Martinez, A.O., Haptoglobin gene expression in human glioblastoma cell lines (2001) Neurosci Lett, 303, pp. 181-184
Lee, M.Y., Kim, S.Y., Choi, J.S., Lee, I.H., Choi, Y.S., Jin, J.Y., Park, S.J., Kim, I.S., Upregulation of haptoglobin in reactive astrocytes after transient forebrain ischemia in rats (2002) J Cereb Blood Flow Metab, 22, pp. 1176-1180
Chen, C.-H., Albers, J.J., Characterization of proteoliposomes containing apoprotein A-I: A new substrate for the measurement of lecithin:cholesterol acyltransferase activity (1982) J Lipid Res, 23, pp. 680-691
Sparks, D.L., Phillips, M.C., Lund-Katz, S., The conformation of apolipoprotein A-I in discoidal and spherical recombinant high density lipoprotein particles (1992) J Biol Chem, 267, pp. 25830-25838
Garcia, A., Barbaras, R., Collet, X., Bogyo, A., Chap, H., Perret, B., High-density lipoprotein 3 receptor-dependent endocytosis pathway in a human hepatoma cell line (HepG2) (1996) Biochemistry, 35, pp. 13064-13071
Bradford, M.M., A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding (1976) Anal Biochem, 72, pp. 248-252
Matz, C.E., Jonas, A., Micellar complexes of human apolipoprotein A-I with phosphatidylcholines and cholesterol prepared from cholate-lipid dispersions (1982) J Biol Chem, 257, pp. 4535-4540
Rader, D. J., Molecular regulation of HDL metabolism and function: Implications for novel therapies (2006) J Clin Invest, 116, pp. 3090-3100
Rader, D. J., Alexander, E. T., Weibel, G. L., Billheimer, J., Rothblat, G. H., Role of reverse cholesterol transport in animals and humans and relationship to atherosclerosis (2009) J Lipid Res, 50, pp. 189-194
Spagnuolo, M. S., Cigliano, L., D'Andrea, L. D., Pedone, C., Abrescia, P., Assignment of the binding site for haptoglobin on apolipoprotein A-I (2005) J Biol Chem, 280, pp. 1193-1198
Kunitake, S. T., Carilli, C. T., Lau, K., Protter, A. A., Naya-Vigne, J., Kane, J. P., Identification of proteins associated with apolipoprotein A-I-containing lipoproteins purified by selected-affinity immunosorption (1994) Biochemistry, 33, pp. 1988-1993
Chapelle, J. P., Albert, A., Smeets, J. P., Heusghem, C., Kulbertus, H. E., Effect of the haptoglobin phenotype on the size of a myocardial infarct (1982) N Engl J Med, 307, pp. 457-463
Langlois, M. R., Delanghe, J. R., Biological and clinical significance of haptoglobin polymorphism in humans (1996) Clin Chem, 42, pp. 1589-1600
Matuszek, M. A., Aristoteli, L. P., Bannon, P. G., Hendel, P. N., Hughes, C. F., Jessup, W., Dean, R. T., Kritharides, L., Haptoglobin elutes from human atherosclerotic coronary arteries - A potential marker of arterial pathology (2003) Atherosclerosis, 168, pp. 389-396
Curtiss, L. K., Boisvert, W. A., Apolipoprotein e and atherosclerosis (2000) Curr Opin Lipidol, 11, pp. 243-251
Curtiss, L. K., Valenta, D. T., Hime, N. J., Rye, K. A., What is so special about apolipoprotein AI in reverse cholesterol transport? (2006) Arterioscler Thromb Vasc Biol, 26, pp. 12-19
Mahley, R. W., Rall, S. C., Apolipoprotein E: Far more than a lipid transport protein (2000) Annu Rev Genomics Hum Genet, 1, pp. 507-537
Rademacher, B. E., Steele, W. J., A general method for the isolation of haptoglobin 1-1, 1-2 and 2-2 from human plasma (1987) Anal Biochem, 160, pp. 119-126
Schumaker, V. N., Puppione, D. L., Sequential flotation ultracentrifugation (1986) Methods in Enzymology, pp. 155-170. , In. Segrest, J. P. Albers, J. J. eds. pp. Academic Press. Orlando, Florida
Shiflett, A. M., Bishop, J. R., Pahwa, A., Hajduk, S. L., Human high density lipoproteins are platforms for assembly of multi-component innate immune complexes (2005) J Biol Chem, 280, pp. 32578-32585
Scanu, A. M., Edelstein, C., HDL: Bridging past and present with a look at the future (2008) FASEB J, 22, pp. 4044-4054
Kim, W. S., Rahmanto, A. S., Kamili, A., Rye, K. -A., Guillemin, G. J., Gelissen, I. C., Jessup, W., Garner, B., Role of ABCG1 and ABCA1 in regulation of neuronal cholesterol efflux to apolipoprotein e discs and suppression of amyloid- peptide generation (2007) J Biol Chem, 282, pp. 2851-2861
Yang, D. S., Small, D. H., Seydel, U., Smith, J. D., Hallmayer, J., Gandy, S. E., Martins, R. N., Apolipoprotein e promotes the binding and uptake of beta-amyloid into Chinese hamster ovary cells in an isoform-specific manner (1999) Neuroscience, 90, pp. 1217-1226
Sanchez, D. J., Armstrong, L., Aguilar, R., Adrian, G. S., Haro, L., Martinez, A. O., Haptoglobin gene expression in human glioblastoma cell lines (2001) Neurosci Lett, 303, pp. 181-184
Lee, M. Y., Kim, S. Y., Choi, J. S., Lee, I. H., Choi, Y. S., Jin, J. Y., Park, S. J., Kim, I. S., Upregulation of haptoglobin in reactive astrocytes after transient forebrain ischemia in rats (2002) J Cereb Blood Flow Metab, 22, pp. 1176-1180
Chen, C. -H., Albers, J. J., Characterization of proteoliposomes containing apoprotein A-I: A new substrate for the measurement of lecithin: cholesterol acyltransferase activity (1982) J Lipid Res, 23, pp. 680-691
Sparks, D. L., Phillips, M. C., Lund-Katz, S., The conformation of apolipoprotein A-I in discoidal and spherical recombinant high density lipoprotein particles (1992) J Biol Chem, 267, pp. 25830-25838
Bradford, M. M., A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding (1976) Anal Biochem, 72, pp. 248-252
Matz, C. E., Jonas, A., Micellar complexes of human apolipoprotein A-I with phosphatidylcholines and cholesterol prepared from cholate-lipid dispersions (1982) J Biol Chem, 257, pp. 4535-4540
Haptoglobin binds the antiatherogenic protein apolipoprotein e - Impairment of apolipoprotein e stimulation of both lecithin: Cholesterol acyltransferase activity and cholesterol uptake by hepatocytes
Haptoglobin (Hpt) binds apolipoprotein A-I (ApoA-I), and impairs its stimulation of lecithin:cholesterol acyltransferase (LCAT). LCAT plays a major role in reverse cholesterol transport (RCT). Apolipoprotein E (ApoE), like ApoA-I, promotes different steps of RCT, including LCAT stimulation. ApoE contains amino acid sequences that are homologous with the ApoA-I region bound by Hpt and are involved in the interaction with LCAT. Therefore, Hpt was expected to also bind ApoE, and inhibit the ApoE stimulatory effect on LCAT. Western blotting and ELISA experiments demonstrated that the Hpt β-subunit binds ApoE. The affinity of Hpt for ApoE was higher than that for ApoA-I. High ratios of Hpt with either apolipoprotein, such as those associated with the acute phase of inflammation, inhibited, in vitro, the stimulatory effect of ApoE on the cholesterol esterification activity of LCAT. Hpt also impaired human hepatoblastoma-derived cell uptake of [3H]cholesterol from proteoliposomes containing ApoE or ApoA-I. We suggest that the interaction between Hpt and ApoE represents a mechanism by which inflammation affects atherosclerosis progression. Hpt might influence ApoE function in processes other than RCT. © 2009 FEBS.
Haptoglobin (Hpt) binds apolipoprotein A-I (ApoA-I), and impairs its stimulation of lecithin:cholesterol acyltransferase (LCAT). LCAT plays a major role in reverse cholesterol transport (RCT). Apolipoprotein E (ApoE), like ApoA-I, promotes different steps of RCT, including LCAT stimulation. ApoE contains amino acid sequences that are homologous with the ApoA-I region bound by Hpt and are involved in the interaction with LCAT. Therefore, Hpt was expected to also bind ApoE, and inhibit the ApoE stimulatory effect on LCAT. Western blotting and ELISA experiments demonstrated that the Hpt β-subunit binds ApoE. The affinity of Hpt for ApoE was higher than that for ApoA-I. High ratios of Hpt with either apolipoprotein, such as those associated with the acute phase of inflammation, inhibited, in vitro, the stimulatory effect of ApoE on the cholesterol esterification activity of LCAT. Hpt also impaired human hepatoblastoma-derived cell uptake of [3H]cholesterol from proteoliposomes containing ApoE or ApoA-I. We suggest that the interaction between Hpt and ApoE represents a mechanism by which inflammation affects atherosclerosis progression. Hpt might influence ApoE function in processes other than RCT. © 2009 FEBS.
Haptoglobin binds the antiatherogenic protein apolipoprotein e - Impairment of apolipoprotein e stimulation of both lecithin: Cholesterol acyltransferase activity and cholesterol uptake by hepatocytes
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Haptoglobin binds the antiatherogenic protein apolipoprotein e - Impairment of apolipoprotein e stimulation of both lecithin: Cholesterol acyltransferase activity and cholesterol uptake by hepatocytes
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Gaglione R, Smaldone G, Di Girolamo R, Piccoli R, Pedone E, Arciello A
* Cell milieu significantly affects the fate of AApoAI amyloidogenic variants: predestination or serendipity? (522 views)
Bba-Gen Subjects (ISSN: 0005-2728, 0006-3002print, 1570-9639print), 2017 Nov 23; 1862(3): 377-384.
Impact Factor: 4.28
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Cigliano L, De Rosa L, Diana D, Di Stasi R, Spagnuolo MS, Maresca B, Fattorusso R, D'Andrea LD
* Structure and biological activity of a conformational constrained apolipoprotein A-I-derived helical peptide targeting the protein haptoglobin (401 views)
Rsc Adv (ISSN: 2046-2069), 2014; 4(93): 51353-51361.
Impact Factor: 3.84
View Export to BibTeX Export to EndNote
Spagnuolo MS, Di Stasi R, De Rosa L, Maresca B, Cigliano L, D'Andrea LD
* Analysis of the haptoglobin binding region on the apolipoprotein A-I-derived P2a peptide (376 views)
J Pept Sci (ISSN: 1075-2617, 1099-1387, 1075-2617print), 2013 Apr; 19(4): 220-226.
Impact Factor: 1.862
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Perrone-Filardi P, Musella F, Savarese G, Cecere M, Marciano C, Scala O, Rengo G, Dellegrottaglie S, Cuocolo A, Leosco D
* Coronary computed tomography: current role and future perspectives for cardiovascular risk stratification (482 views)
Eur Heart J-Card Img (ISSN: 2047-2412, 2047-2404, 2047-2412electronic), 2012 Jun; 13(6): 453-458.
Impact Factor: 3.669
View Export to BibTeX Export to EndNote
Bucci M, Cigliano L, Vellecco V, D'Andrea LD, Ziaco B, Rossi A, Sautebin L, Carlucci A, Abrescia P, Pedone C, Ianaro A, Cirino G
* Apolipoprotein A-I (ApoA-I) mimetic peptide P2a by restoring cholesterol esterification unmasks ApoA-I anti-inflammatory endogenous activity in vivo (461 views)
J Pharmacol Exp Ther (ISSN: 1521-0103, 0022-3565), 2012 Mar; 340(3): 716-722.
Impact Factor: 3.891
View Export to BibTeX Export to EndNote
Monti DM(1), Di Gaetano S, Del Giudice R, Giangrande C, Amoresano A, Monti M, Arciello A, Piccoli R
* Apolipoprotein A-I amyloidogenic variant L174S, expressed and isolated from stably transfected mammalian cells, is associated with fatty acids (324 views)
Amyloid (ISSN: 1350-6129), 2012 Mar; 19(1): 21-27.
Impact Factor: 4.436
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Santulli G, Cipolletta E, Sorriento D, Del Giudice C, Anastasio A, Monaco S, Maione AS, Condorelli G, Puca A, Trimarco B, Illario M, Iaccarino G
* CaMK4 gene deletion induces hypertension (349 views)
J Am Heart Assoc Journal Of The American Heart Association (ISSN: 2047-9980), 2012; 1(4): N/D-N/D.
Impact Factor: 2.882
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Raimondi S, Guglielmi F, Giorgetti S, Di Gaetano S, Arciello A, Monti DM, Relini A, Nichino D, Doglia SM, Natalello A, Pucci P, Mangione P, Obici L, Merlini G, Stoppini M, Robustelli P, Tartaglia GG, Vendruscolo M, Dobson CM, Piccoli R, Bellotti V
* Effects of the Known Pathogenic Mutations on the Aggregation Pathway of the Amyloidogenic Peptide of Apolipoprotein A-I (459 views)
J Mol Biol (ISSN: 0022-2836, 1089-8638, 1089-8638electronic), 2011 Apr 1; 407(3): 465-476.
Impact Factor: 4.001
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Giacco R, Clemente G, Cipriano D, Luongo D, Viscovo D, Patti L, Di Marino L, Giacco A, Naviglio D, Bianchi MA, Ciati R, Brighenti F, Rivellese AA, Riccardi G
* Effects of the regular consumption of wholemeal wheat foods on cardiovascular risk factors in healthy people (950 views)
Nutrition (ISSN: 0939-4753, 1590-3729electronic), 2010 Mar; 20(3): 186-194.
Impact Factor: 3.438
View Export to BibTeX Export to EndNote
Capaccio D, Ciccodicola A, Sabatino L, Casamassimi A, Pancione M, Fucci A, Febbraro, Merlino A, Graziano G, Colantuoni V
* A novel germline mutation in Peroxisome Proliferator-Activated Receptor γ gene associated with large intestine polyp formation and dyslipidemia (431 views)
Bba-Gen Subjects (ISSN: 0925-4439, 0006-3002, 1570-9639), 2010; 1802(6): 572-581.
Impact Factor: 2.773
View Export to BibTeX Export to EndNote
Cigliano L, Pugliese CR, Spagnuolo MS, Palumbo R, Abrescia P
* Haptoglobin Binds The Anti-Atherogenic Protein Apolipoprotein E: Impairment Of The Apolipoprotein E Stimulation On Both The Enzyme Lecithin-Cholesterol Acyl-Transferase Activity And The Cholesterol Uptake By Hepatocytes (274 views)
Febs J, 2009; 276: 6158-6171.
Impact Factor: 3.986
View Export to BibTeX Export to EndNote
Cigliano L, D'Andrea LD, Maresca B, Serino M, Carlucci A, Salvatore A, Spagnuolo MS, Scigliuolo G, Pedone C, Abrescia P
* Relevance of the amino acid conversions L144R (Zaragoza) and L159P (Zavalla) in the apolipoprotein A-I binding site for haptoglobin (393 views)
Biol Chem Biological Chemistry (ISSN: 1431-6730, 1437-4315), 2008 Nov; 389(11): 1421-1426.
Impact Factor: 3.035
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Cigliano L, Maresca B, Salvatore A, Nino M, Monfrecola G, Ayala F, Carlucci A, Pugliese RC, Pedone C, Abrescia P
* Haptoglobin from psoriatic patients exhibits decreased activity in binding haemoglobin and inhibiting lecithin-cholesterol acyltransferase activity (417 views)
Journal Of The European Academy Of Dermatology And Venereology (ISSN: 1468-3083, 0926-9959), 2008 Apr; 22(4): 417-425.
Impact Factor: 2.276
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Salvatore A, Cigliano L, Bucci EM, Corpillo D, Velasco S, Carlucci A, Pedone C, Abrescia P
* Haptoglobin binding to apolipoprotein A-I prevents damage from hydroxyl radicals on its stimulatory activity of the enzyme lecithin-cholesterol acyl-transferase (495 views)
Biochemistry (ISSN: 0006-2960, 1520-4995, 1520-4995electronic), 2007 Oct 2; 46(39): 11158-11168.
Impact Factor: 3.368
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Amorini AM, Bellia F, Di Pietro V, Giardina B, La Mendola D, Lazzarino G, Sortino S, Tavazzi B, Rizzarelli E, Vecchio G
* Synthesis And Antioxidant Activity Of New Homocarnosine Beta-Cyclodextrin Conjugates (379 views)
Eur J Med Chem (ISSN: 0223-5234, 1768-3254, 1768-3254electronic), 2007 Jul; 42(7): 910-920.
Impact Factor: 2.301
View Export to BibTeX Export to EndNote
Spagnuolo MS, Cigliano L, D'Andrea LD, Pedone C, Abrescia P
* Assignment of the binding site for haptoglobin on apolipoprotein A-I (496 views)
Jbc Papers (ISSN: 0021-9258, 1083-351x, 0021-9258linking), 2005 Jan 14; 280(2): 1193-1198.
Impact Factor: 5.854
View Export to BibTeX Export to EndNote
Giacco R, Clemente G, Luongo D, Lasorella G, Fiume I, Brouns F, Bornet F, Patti L, Cipriano P, Rivellese AA, Riccardi G
* Effects of short-chain fructo-oligosaccharides on glucose and lipid metabolism in mild hypercholesterolaemic individuals (486 views)
Clin Nutr (ISSN: 0261-5614, 0261-5614linking), 2004 Jun; 23(3): 331-340.
Impact Factor: 2.019
View Export to BibTeX Export to EndNote
Pauciullo P, Giannino A, De Michele M, Gentile M, Liguori R, Argiriou A, Carlotto A, Faccenda F, Mancini M, Bond MG, De Simone V, Rubba P
* Increased carotid artery intima-media thickness is associated with a novel mutation of low-density lipoprotein receptor independently of major cardiovascular risk factors (735 views)
Metab Clin Exp (ISSN: 0026-0495, 1532-8600), 2003; 52(11): 1433-1438.
Impact Factor: 2.013
View Export to BibTeX Export to EndNote
Colao A, Di Somma C, Pivonello R, Cuocolo A, Spinelli L, Bonaduce D, Salvatore M, Lombardi G
* The cardiovascular risk of adult GH deficiency (GHD) improved after GH replacement and worsened in untreated GHD: A 12-month prospective study (401 views)
J Clin Endocrinol Metab (ISSN: 0021-972x), 2002 Mar; 87(3): 1088-1093.
Impact Factor: 5.199
View Export to BibTeX Export to EndNote
* Cell milieu significantly affects the fate of AApoAI amyloidogenic variants: predestination or serendipity? (522 views)
Bba-Gen Subjects (ISSN: 0005-2728, 0006-3002print, 1570-9639print), 2017 Nov 23; 1862(3): 377-384.
Impact Factor: 4.28
View Export to BibTeX Export to EndNote
Cigliano L, De Rosa L, Diana D, Di Stasi R, Spagnuolo MS, Maresca B, Fattorusso R, D'Andrea LD
* Structure and biological activity of a conformational constrained apolipoprotein A-I-derived helical peptide targeting the protein haptoglobin (401 views)
Rsc Adv (ISSN: 2046-2069), 2014; 4(93): 51353-51361.
Impact Factor: 3.84
View Export to BibTeX Export to EndNote
Spagnuolo MS, Di Stasi R, De Rosa L, Maresca B, Cigliano L, D'Andrea LD
* Analysis of the haptoglobin binding region on the apolipoprotein A-I-derived P2a peptide (376 views)
J Pept Sci (ISSN: 1075-2617, 1099-1387, 1075-2617print), 2013 Apr; 19(4): 220-226.
Impact Factor: 1.862
View Export to BibTeX Export to EndNote
Perrone-Filardi P, Musella F, Savarese G, Cecere M, Marciano C, Scala O, Rengo G, Dellegrottaglie S, Cuocolo A, Leosco D
* Coronary computed tomography: current role and future perspectives for cardiovascular risk stratification (482 views)
Eur Heart J-Card Img (ISSN: 2047-2412, 2047-2404, 2047-2412electronic), 2012 Jun; 13(6): 453-458.
Impact Factor: 3.669
View Export to BibTeX Export to EndNote
Bucci M, Cigliano L, Vellecco V, D'Andrea LD, Ziaco B, Rossi A, Sautebin L, Carlucci A, Abrescia P, Pedone C, Ianaro A, Cirino G
* Apolipoprotein A-I (ApoA-I) mimetic peptide P2a by restoring cholesterol esterification unmasks ApoA-I anti-inflammatory endogenous activity in vivo (461 views)
J Pharmacol Exp Ther (ISSN: 1521-0103, 0022-3565), 2012 Mar; 340(3): 716-722.
Impact Factor: 3.891
View Export to BibTeX Export to EndNote
Monti DM(1), Di Gaetano S, Del Giudice R, Giangrande C, Amoresano A, Monti M, Arciello A, Piccoli R
* Apolipoprotein A-I amyloidogenic variant L174S, expressed and isolated from stably transfected mammalian cells, is associated with fatty acids (324 views)
Amyloid (ISSN: 1350-6129), 2012 Mar; 19(1): 21-27.
Impact Factor: 4.436
View Export to BibTeX Export to EndNote
Santulli G, Cipolletta E, Sorriento D, Del Giudice C, Anastasio A, Monaco S, Maione AS, Condorelli G, Puca A, Trimarco B, Illario M, Iaccarino G
* CaMK4 gene deletion induces hypertension (349 views)
J Am Heart Assoc Journal Of The American Heart Association (ISSN: 2047-9980), 2012; 1(4): N/D-N/D.
Impact Factor: 2.882
View Export to BibTeX Export to EndNote
Raimondi S, Guglielmi F, Giorgetti S, Di Gaetano S, Arciello A, Monti DM, Relini A, Nichino D, Doglia SM, Natalello A, Pucci P, Mangione P, Obici L, Merlini G, Stoppini M, Robustelli P, Tartaglia GG, Vendruscolo M, Dobson CM, Piccoli R, Bellotti V
* Effects of the Known Pathogenic Mutations on the Aggregation Pathway of the Amyloidogenic Peptide of Apolipoprotein A-I (459 views)
J Mol Biol (ISSN: 0022-2836, 1089-8638, 1089-8638electronic), 2011 Apr 1; 407(3): 465-476.
Impact Factor: 4.001
View Export to BibTeX Export to EndNote
Giacco R, Clemente G, Cipriano D, Luongo D, Viscovo D, Patti L, Di Marino L, Giacco A, Naviglio D, Bianchi MA, Ciati R, Brighenti F, Rivellese AA, Riccardi G
* Effects of the regular consumption of wholemeal wheat foods on cardiovascular risk factors in healthy people (950 views)
Nutrition (ISSN: 0939-4753, 1590-3729electronic), 2010 Mar; 20(3): 186-194.
Impact Factor: 3.438
View Export to BibTeX Export to EndNote
Capaccio D, Ciccodicola A, Sabatino L, Casamassimi A, Pancione M, Fucci A, Febbraro, Merlino A, Graziano G, Colantuoni V
* A novel germline mutation in Peroxisome Proliferator-Activated Receptor γ gene associated with large intestine polyp formation and dyslipidemia (431 views)
Bba-Gen Subjects (ISSN: 0925-4439, 0006-3002, 1570-9639), 2010; 1802(6): 572-581.
Impact Factor: 2.773
View Export to BibTeX Export to EndNote
Cigliano L, Pugliese CR, Spagnuolo MS, Palumbo R, Abrescia P
* Haptoglobin Binds The Anti-Atherogenic Protein Apolipoprotein E: Impairment Of The Apolipoprotein E Stimulation On Both The Enzyme Lecithin-Cholesterol Acyl-Transferase Activity And The Cholesterol Uptake By Hepatocytes (274 views)
Febs J, 2009; 276: 6158-6171.
Impact Factor: 3.986
View Export to BibTeX Export to EndNote
Cigliano L, D'Andrea LD, Maresca B, Serino M, Carlucci A, Salvatore A, Spagnuolo MS, Scigliuolo G, Pedone C, Abrescia P
* Relevance of the amino acid conversions L144R (Zaragoza) and L159P (Zavalla) in the apolipoprotein A-I binding site for haptoglobin (393 views)
Biol Chem Biological Chemistry (ISSN: 1431-6730, 1437-4315), 2008 Nov; 389(11): 1421-1426.
Impact Factor: 3.035
View Export to BibTeX Export to EndNote
Cigliano L, Maresca B, Salvatore A, Nino M, Monfrecola G, Ayala F, Carlucci A, Pugliese RC, Pedone C, Abrescia P
* Haptoglobin from psoriatic patients exhibits decreased activity in binding haemoglobin and inhibiting lecithin-cholesterol acyltransferase activity (417 views)
Journal Of The European Academy Of Dermatology And Venereology (ISSN: 1468-3083, 0926-9959), 2008 Apr; 22(4): 417-425.
Impact Factor: 2.276
View Export to BibTeX Export to EndNote
Salvatore A, Cigliano L, Bucci EM, Corpillo D, Velasco S, Carlucci A, Pedone C, Abrescia P
* Haptoglobin binding to apolipoprotein A-I prevents damage from hydroxyl radicals on its stimulatory activity of the enzyme lecithin-cholesterol acyl-transferase (495 views)
Biochemistry (ISSN: 0006-2960, 1520-4995, 1520-4995electronic), 2007 Oct 2; 46(39): 11158-11168.
Impact Factor: 3.368
View Export to BibTeX Export to EndNote
Amorini AM, Bellia F, Di Pietro V, Giardina B, La Mendola D, Lazzarino G, Sortino S, Tavazzi B, Rizzarelli E, Vecchio G
* Synthesis And Antioxidant Activity Of New Homocarnosine Beta-Cyclodextrin Conjugates (379 views)
Eur J Med Chem (ISSN: 0223-5234, 1768-3254, 1768-3254electronic), 2007 Jul; 42(7): 910-920.
Impact Factor: 2.301
View Export to BibTeX Export to EndNote
Spagnuolo MS, Cigliano L, D'Andrea LD, Pedone C, Abrescia P
* Assignment of the binding site for haptoglobin on apolipoprotein A-I (496 views)
Jbc Papers (ISSN: 0021-9258, 1083-351x, 0021-9258linking), 2005 Jan 14; 280(2): 1193-1198.
Impact Factor: 5.854
View Export to BibTeX Export to EndNote
Giacco R, Clemente G, Luongo D, Lasorella G, Fiume I, Brouns F, Bornet F, Patti L, Cipriano P, Rivellese AA, Riccardi G
* Effects of short-chain fructo-oligosaccharides on glucose and lipid metabolism in mild hypercholesterolaemic individuals (486 views)
Clin Nutr (ISSN: 0261-5614, 0261-5614linking), 2004 Jun; 23(3): 331-340.
Impact Factor: 2.019
View Export to BibTeX Export to EndNote
Pauciullo P, Giannino A, De Michele M, Gentile M, Liguori R, Argiriou A, Carlotto A, Faccenda F, Mancini M, Bond MG, De Simone V, Rubba P
* Increased carotid artery intima-media thickness is associated with a novel mutation of low-density lipoprotein receptor independently of major cardiovascular risk factors (735 views)
Metab Clin Exp (ISSN: 0026-0495, 1532-8600), 2003; 52(11): 1433-1438.
Impact Factor: 2.013
View Export to BibTeX Export to EndNote
Colao A, Di Somma C, Pivonello R, Cuocolo A, Spinelli L, Bonaduce D, Salvatore M, Lombardi G
* The cardiovascular risk of adult GH deficiency (GHD) improved after GH replacement and worsened in untreated GHD: A 12-month prospective study (401 views)
J Clin Endocrinol Metab (ISSN: 0021-972x), 2002 Mar; 87(3): 1088-1093.
Impact Factor: 5.199
View Export to BibTeX Export to EndNote
19 Records (19 excluding Abstracts).
Total impact factor: 65.123 (65.123 excluding Abstracts).
Total 5 year impact factor: 62.016 (62.016 excluding Abstracts).
Total impact factor: 65.123 (65.123 excluding Abstracts).
Total 5 year impact factor: 62.016 (62.016 excluding Abstracts).
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