Haptoglobin binds the antiatherogenic protein apolipoprotein e - Impairment of apolipoprotein e stimulation of both lecithin: Cholesterol acyltransferase activity and cholesterol uptake by hepatocytes
Haptoglobin binds the antiatherogenic protein apolipoprotein e - Impairment of apolipoprotein e stimulation of both lecithin: Cholesterol acyltransferase activity and cholesterol uptake by hepatocytes(398 views) Cigliano L, Pugliese CR, Spagnuolo MS, Palumbo R, Abrescia P
Keywords: Apolipoprotein A-I, Haptoglobin, High-Density Lipoprotein (hdl), Lecithin:Cholesterol Acyltransferase (lcat), Low Density Lipoprotein, Phosphatidylcholine Sterol Acyltransferase, Protein Subunit, Very Low Density Lipoprotein, Article, Atherosclerosis, Binding Affinity, Cholesterol Esterification, Cholesterol Transport, Controlled Study, Electrophoresis, Enzyme Activation, Enzyme Activity, Enzyme Linked Immunosorbent Assay, Human, Human Cell, Human Tissue, Immunoblotting, Inflammation, Liver Cell, Molecular Interaction, Nucleotide Sequence, Priority Journal, Protein Protein Interaction, Western Blotting, Apolipoproteins E, Competitive, Cell Line, Tumor, Hemoglobins, Hepatocytes, Vldl, Phosphatidylcholine-Sterol O-Acyltransferase, Lecithin: Cholesterol Acyltransferase (lcat),
Affiliations: *** IBB - CNR ***
Dipartimento Delle Scienze Biologiche, Università di Napoli Federico II, via Mezzocannone 8, 80134 Napoli, Italy
Istituto per Il Sistema Produzione Animale in Ambiente Mediterraneo, Consiglio Nazionale Delle Ricerche, Napoli, Italy
Istituto di Biostrutture e Bioimmagini, Consiglio Nazionale Delle Ricerche, Napoli, Italy
References: Libby, P., Ridker, P.M., Maseri, A., Inflammation and atherosclerosis (2002) Circulation, 105, pp. 1135-114
Libby, P., Inflammatory mechanisms: The molecular basis of inflammation and disease (2007) Nutr Rev, 65, pp. 140-146
Kontush, A., Chapman, M.J., Functionally defective high-density lipoprotein: A new therapeutic target at the crossroads of dyslipidemia, inflammation, and atherosclerosis (2006) Pharmacol Rev, 58, pp. 342-374
Rader, D.J., Molecular regulation of HDL metabolism and function: Implications for novel therapies (2006) J Clin Invest, 116, pp. 3090-3100
Rader, D.J., Alexander, E.T., Weibel, G.L., Billheimer, J., Rothblat, G.H., Role of reverse cholesterol transport in animals and humans and relationship to atherosclerosis (2009) J Lipid Res, 50, pp. 189-194
Spagnuolo, M.S., Cigliano, L., D'Andrea, L.D., Pedone, C., Abrescia, P., Assignment of the binding site for haptoglobin on apolipoprotein A-I (2005) J Biol Chem, 280, pp. 1193-1198
Porta, A., Cassano, E., Balestrieri, M., Bianco, M., Picone, R., De Stefano, C., Abrescia, P., Haptoglobin transport into human ovarian follicles and its binding to apolipoprotein A-I (1999) Zygote, 7, pp. 67-77
Kunitake, S.T., Carilli, C.T., Lau, K., Protter, A.A., Naya-Vigne, J., Kane, J.P., Identification of proteins associated with apolipoprotein A-I-containing lipoproteins purified by selected-affinity immunosorption (1994) Biochemistry, 33, pp. 1988-1993
Chapelle, J.P., Albert, A., Smeets, J.P., Heusghem, C., Kulbertus, H.E., Effect of the haptoglobin phenotype on the size of a myocardial infarct (1982) N Engl J Med, 307, pp. 457-463
Delanghe, J., Cambier, B., Langlois, M., De Buyzere, M., Neels, H., De Bacquer, D., Van Cauwelaert, P., Haptoglobin polymorphism, a genetic risk factor in coronary artery bypass surgery (1997) Atherosclerosis, 132, pp. 215-219
Giblett, E., Haptoglobin (1974) Structure and Function of Plasma Proteins, pp. 55-72. , In. Allison, A.C. ed. pp. Plenum Press. New York
Langlois, M.R., Delanghe, J.R., Biological and clinical significance of haptoglobin polymorphism in humans (1996) Clin Chem, 42, pp. 1589-1600
Balestrieri, M., Cigliano, L., De Simone, M.L., Dale, B., Abrescia, P., Haptoglobin inhibits lecithin-cholesterol acyltransferase in human ovarian follicular fluid (2001) Mol Reprod Dev, 59, pp. 186-191
Cigliano, L., Spagnuolo, M.S., Dale, B., Balestrieri, M., Abrescia, P., Estradiol esterification in the human preovulatory follicle (2001) Steroids, 66, pp. 889-896
Salvatore, A., Cigliano, L., Bucci, E.M., Corpillo, D., Velasco, S., Carlucci, A., Pedone, C., Abrescia, P., Haptoglobin binding to apolipoprotein A-I prevents damage from hydroxyl radicals on its stimulatory activity of the enzyme lecithin-cholesterol acyl-transferase (2007) Biochemistry, 46, pp. 11158-11168
Braeckman, L., De Bacquer, D., Delanghe, J., Claeys, L., De Backer, G., Associations between haptoglobin polymorphism, lipids, lipoproteins and inflammatory variables (1999) Atherosclerosis, 143, pp. 383-388
De Bacquer, D., De Backer, G., Langlois, M., Delanghe, J., Kesteloot, H., Kornitzer, M., Haptoglobin polymorphism as a risk factor for coronary heart disease mortality (2001) Atherosclerosis, 157, pp. 161-166
Matuszek, M.A., Aristoteli, L.P., Bannon, P.G., Hendel, P.N., Hughes, C.F., Jessup, W., Dean, R.T., Kritharides, L., Haptoglobin elutes from human atherosclerotic coronary arteries - A potential marker of arterial pathology (2003) Atherosclerosis, 168, pp. 389-396
Greenow, K., Pearce, N.J., Ramji, D.P., The key role of apolipoprotein e in atherosclerosis (2005) J Mol Med, 83, pp. 329-342
Curtiss, L.K., Boisvert, W.A., Apolipoprotein e and atherosclerosis (2000) Curr Opin Lipidol, 11, pp. 243-251
Curtiss, L.K., Valenta, D.T., Hime, N.J., Rye, K.A., What is so special about apolipoprotein AI in reverse cholesterol transport? (2006) Arterioscler Thromb Vasc Biol, 26, pp. 12-19
Zhao, Y., Thorngate, F.E., Weisgraber, K.H., Williams, D.L., Parks, J.S., Apolipoprotein e is the major physiological activator of lecithin-cholesterol acyltransferase (LCAT) on apolipoprotein B lipoproteins (2005) Biochemistry, 44, pp. 1013-1025
Mahley, R.W., Rall, S.C., Apolipoprotein E: Far more than a lipid transport protein (2000) Annu Rev Genomics Hum Genet, 1, pp. 507-537
Rademacher, B.E., Steele, W.J., A general method for the isolation of haptoglobin 1-1, 1-2 and 2-2 from human plasma (1987) Anal Biochem, 160, pp. 119-126
Schumaker, V.N., Puppione, D.L., Sequential flotation ultracentrifugation (1986) Methods in Enzymology, pp. 155-170. , In. Segrest, J.P. Albers, J.J. eds. pp. Academic Press. Orlando, Florida
Shiflett, A.M., Bishop, J.R., Pahwa, A., Hajduk, S.L., Human high density lipoproteins are platforms for assembly of multi-component innate immune complexes (2005) J Biol Chem, 280, pp. 32578-32585
Karlsson, H., Leanderson, P., Tagesson, C., Lindahl, M., Lipoproteomics I: Mapping of proteins in low-density lipoprotein using two-dimensional gel electrophoresis and mass spectrometry (2005) Proteomics, 5 (2), pp. 551-565. , DOI 10.1002/pmic.200300938
Xu, S., Laccotripe, M., Huang, X., Rigotti, A., Zannis, V.I., Krieger, M., Apolipoproteins of HDL can directly mediate binding to the scavenger receptor SR-BI, an HDL receptor that mediates selective lipid uptake (1997) J Lipid Res, 38, pp. 1289-1298
Scanu, A.M., Edelstein, C., HDL: Bridging past and present with a look at the future (2008) FASEB J, 22, pp. 4044-4054
Kim, W.S., Rahmanto, A.S., Kamili, A., Rye, K.-A., Guillemin, G.J., Gelissen, I.C., Jessup, W., Garner, B., Role of ABCG1 and ABCA1 in regulation of neuronal cholesterol efflux to apolipoprotein e discs and suppression of amyloid-β peptide generation (2007) J Biol Chem, 282, pp. 2851-2861
Hirsch-Reinshagen, V., Wellington, C.L., Cholesterol metabolism, apolipoprotein E, adenosine triphosphate-binding cassette transporters, and Alzheimer's disease (2007) Curr Opin Lipidol, 18, pp. 325-332
Yang, D.S., Small, D.H., Seydel, U., Smith, J.D., Hallmayer, J., Gandy, S.E., Martins, R.N., Apolipoprotein e promotes the binding and uptake of beta-amyloid into Chinese hamster ovary cells in an isoform-specific manner (1999) Neuroscience, 90, pp. 1217-1226
Koistinaho, M., Lin, S., Wu, X., Esterman, M., Koger, D., Hanson, J., Higgs, R., Bales, K.R., Apolipoprotein e promotes astrocyte colocalization and degradation of deposited amyloid-beta peptides (2004) Nat Med, 10, pp. 719-726
Sadowski, M., Pankiewicz, J., Scholtzova, H., Ripellino, J.A., Li, Y., Schmidt, S.D., Mathews, P.M., Sigurdsson, E.M., A synthetic peptide blocking the apolipoprotein E/beta-amyloid binding mitigates beta-amyloid toxicity and fibril formation in vitro and reduces beta-amyloid plaques in transgenic mice (2004) Am J Pathol, 165, pp. 937-948
Sanchez, D.J., Armstrong, L., Aguilar, R., Adrian, G.S., Haro, L., Martinez, A.O., Haptoglobin gene expression in human glioblastoma cell lines (2001) Neurosci Lett, 303, pp. 181-184
Lee, M.Y., Kim, S.Y., Choi, J.S., Lee, I.H., Choi, Y.S., Jin, J.Y., Park, S.J., Kim, I.S., Upregulation of haptoglobin in reactive astrocytes after transient forebrain ischemia in rats (2002) J Cereb Blood Flow Metab, 22, pp. 1176-1180
Chen, C.-H., Albers, J.J., Characterization of proteoliposomes containing apoprotein A-I: A new substrate for the measurement of lecithin:cholesterol acyltransferase activity (1982) J Lipid Res, 23, pp. 680-691
Sparks, D.L., Phillips, M.C., Lund-Katz, S., The conformation of apolipoprotein A-I in discoidal and spherical recombinant high density lipoprotein particles (1992) J Biol Chem, 267, pp. 25830-25838
Garcia, A., Barbaras, R., Collet, X., Bogyo, A., Chap, H., Perret, B., High-density lipoprotein 3 receptor-dependent endocytosis pathway in a human hepatoma cell line (HepG2) (1996) Biochemistry, 35, pp. 13064-13071
Bradford, M.M., A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding (1976) Anal Biochem, 72, pp. 248-252
Matz, C.E., Jonas, A., Micellar complexes of human apolipoprotein A-I with phosphatidylcholines and cholesterol prepared from cholate-lipid dispersions (1982) J Biol Chem, 257, pp. 4535-4540
Rader, D. J., Molecular regulation of HDL metabolism and function: Implications for novel therapies (2006) J Clin Invest, 116, pp. 3090-3100
Rader, D. J., Alexander, E. T., Weibel, G. L., Billheimer, J., Rothblat, G. H., Role of reverse cholesterol transport in animals and humans and relationship to atherosclerosis (2009) J Lipid Res, 50, pp. 189-194
Spagnuolo, M. S., Cigliano, L., D'Andrea, L. D., Pedone, C., Abrescia, P., Assignment of the binding site for haptoglobin on apolipoprotein A-I (2005) J Biol Chem, 280, pp. 1193-1198
Kunitake, S. T., Carilli, C. T., Lau, K., Protter, A. A., Naya-Vigne, J., Kane, J. P., Identification of proteins associated with apolipoprotein A-I-containing lipoproteins purified by selected-affinity immunosorption (1994) Biochemistry, 33, pp. 1988-1993
Chapelle, J. P., Albert, A., Smeets, J. P., Heusghem, C., Kulbertus, H. E., Effect of the haptoglobin phenotype on the size of a myocardial infarct (1982) N Engl J Med, 307, pp. 457-463
Langlois, M. R., Delanghe, J. R., Biological and clinical significance of haptoglobin polymorphism in humans (1996) Clin Chem, 42, pp. 1589-1600
Matuszek, M. A., Aristoteli, L. P., Bannon, P. G., Hendel, P. N., Hughes, C. F., Jessup, W., Dean, R. T., Kritharides, L., Haptoglobin elutes from human atherosclerotic coronary arteries - A potential marker of arterial pathology (2003) Atherosclerosis, 168, pp. 389-396
Curtiss, L. K., Boisvert, W. A., Apolipoprotein e and atherosclerosis (2000) Curr Opin Lipidol, 11, pp. 243-251
Curtiss, L. K., Valenta, D. T., Hime, N. J., Rye, K. A., What is so special about apolipoprotein AI in reverse cholesterol transport? (2006) Arterioscler Thromb Vasc Biol, 26, pp. 12-19
Mahley, R. W., Rall, S. C., Apolipoprotein E: Far more than a lipid transport protein (2000) Annu Rev Genomics Hum Genet, 1, pp. 507-537
Rademacher, B. E., Steele, W. J., A general method for the isolation of haptoglobin 1-1, 1-2 and 2-2 from human plasma (1987) Anal Biochem, 160, pp. 119-126
Schumaker, V. N., Puppione, D. L., Sequential flotation ultracentrifugation (1986) Methods in Enzymology, pp. 155-170. , In. Segrest, J. P. Albers, J. J. eds. pp. Academic Press. Orlando, Florida
Shiflett, A. M., Bishop, J. R., Pahwa, A., Hajduk, S. L., Human high density lipoproteins are platforms for assembly of multi-component innate immune complexes (2005) J Biol Chem, 280, pp. 32578-32585
Scanu, A. M., Edelstein, C., HDL: Bridging past and present with a look at the future (2008) FASEB J, 22, pp. 4044-4054
Kim, W. S., Rahmanto, A. S., Kamili, A., Rye, K. -A., Guillemin, G. J., Gelissen, I. C., Jessup, W., Garner, B., Role of ABCG1 and ABCA1 in regulation of neuronal cholesterol efflux to apolipoprotein e discs and suppression of amyloid- peptide generation (2007) J Biol Chem, 282, pp. 2851-2861
Yang, D. S., Small, D. H., Seydel, U., Smith, J. D., Hallmayer, J., Gandy, S. E., Martins, R. N., Apolipoprotein e promotes the binding and uptake of beta-amyloid into Chinese hamster ovary cells in an isoform-specific manner (1999) Neuroscience, 90, pp. 1217-1226
Sanchez, D. J., Armstrong, L., Aguilar, R., Adrian, G. S., Haro, L., Martinez, A. O., Haptoglobin gene expression in human glioblastoma cell lines (2001) Neurosci Lett, 303, pp. 181-184
Lee, M. Y., Kim, S. Y., Choi, J. S., Lee, I. H., Choi, Y. S., Jin, J. Y., Park, S. J., Kim, I. S., Upregulation of haptoglobin in reactive astrocytes after transient forebrain ischemia in rats (2002) J Cereb Blood Flow Metab, 22, pp. 1176-1180
Chen, C. -H., Albers, J. J., Characterization of proteoliposomes containing apoprotein A-I: A new substrate for the measurement of lecithin: cholesterol acyltransferase activity (1982) J Lipid Res, 23, pp. 680-691
Sparks, D. L., Phillips, M. C., Lund-Katz, S., The conformation of apolipoprotein A-I in discoidal and spherical recombinant high density lipoprotein particles (1992) J Biol Chem, 267, pp. 25830-25838
Bradford, M. M., A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding (1976) Anal Biochem, 72, pp. 248-252
Matz, C. E., Jonas, A., Micellar complexes of human apolipoprotein A-I with phosphatidylcholines and cholesterol prepared from cholate-lipid dispersions (1982) J Biol Chem, 257, pp. 4535-4540
Haptoglobin binds the antiatherogenic protein apolipoprotein e - Impairment of apolipoprotein e stimulation of both lecithin: Cholesterol acyltransferase activity and cholesterol uptake by hepatocytes
Haptoglobin binds the antiatherogenic protein apolipoprotein e - Impairment of apolipoprotein e stimulation of both lecithin: Cholesterol acyltransferase activity and cholesterol uptake by hepatocytes
No results.
Haptoglobin binds the antiatherogenic protein apolipoprotein e - Impairment of apolipoprotein e stimulation of both lecithin: Cholesterol acyltransferase activity and cholesterol uptake by hepatocytes
Santulli G, Cipolletta E, Sorriento D, Del Giudice C, Anastasio A, Monaco S, Maione AS, Condorelli G, Puca A, Trimarco B, Illario M, Iaccarino G * CaMK4 gene deletion induces hypertension(349 views) J Am Heart Assoc Journal Of The American Heart Association (ISSN: 2047-9980), 2012; 1(4): N/D-N/D. Impact Factor:2.882 ViewExport to BibTeXExport to EndNote