Institute of Biostructures and Bioimages, National Research Council, University of Naples Federico II, Naples, Italy
Department of Biomorphological and Functional Sciences, University of Naples Federico II, Edificio 10, Via S. Pansini 5, 80131 Naples, Italy
Department of Pharmaceutical Chemistry and Toxicology, University of Naples Federico II, Naples, Italy
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Avraamides, C. J., Garmy-Susini, B., Varner, J. A., Integrins in angiogenesis and lymphangiogenesis (2008) Nat Rev Cancer, 8, pp. 604-61
Hood, J. D., Cheresh, D. A., Role of integrins in cell invasion and migration (2002) Nature Reviews Cancer, 2 (2), pp. 91-100
Stupack, D. G., Cheresh, D. A., Get a ligand, get a life: Integrins, signaling and cell survival (2002) J Cell Sci, 115, pp. 3729-3738
Hood, J. D., Frausto, R., Kiosses, W. B., Schwartz, M. A., Cheresh, D. A., Differential v integrin-mediated Ras-ERK signaling during two pathways of angiogenesis (2003) Journal of Cell Biology, 162 (5), pp. 933-943. , DOI 10. 1083/jcb. 200304105
Xiong, J. -P., Stehle, T., Diefenbach, B., Zhang, R., Dunker, R., Scott, D. L., Joachimiak, A., Arnaout, M. A., Crystal structure of the extracettutar segment of integrin V 3 (2001) Science, 294 (5541), pp. 339-345. , DOI 10. 1126/science. 1064535
Mahabeleshwar, G. H., Feng, W., Reddy, K., Plow, E. F., Byzova, T. V., Mechanisms of integrin-vascular endothelial growth factor receptor cross-activation in angiogenesis (2007) Circulation Research, 101 (6), pp. 570-580. , DOI 10. 1161/CIRCRESAHA. 107. 155655
Byzova, T. V., Goldman, C. K., Pampori, N., A mechanism for modulation of cellular responses to VEGF: Activation of the integrins (2000) Mol Cell, 6, pp. 851-860
Albelda, S. M., Mette, S. A., Elder, D. E., Integrin distribution in malignant melanoma: Association of the 3 subunit with tumor progression (1990) Cancer Res, 50, pp. 6757-6764
Carriero, M. V., Del Vecchio, S., Capozzoli, M., Urokinase receptor interacts with (v) 5 vitronectin receptor, promoting urokinase-dependent cell migration in breast cancer (1999) Cancer Res, 59, pp. 5307-5314
Sipkins, D. A., Cheresh, D. A., Kazemi, M. R., Nevin, L. M., Bednarski, M. D., Li, K. C. P., Detection of tumor angiogenesis in vivo by (v) 3- targeted magnetic resonance imaging (1998) Nature Medicine, 4 (5), pp. 623-626. , DOI 10. 1038/nm0598-623
Ellegala, D. B., Leong-Poi, H., Carpenter, J. E., Imaging tumor angiogenesis with contrast ultrasound and microbubbles targeted to (v) 3 (2003) Circulation, 108, pp. 336-341
Janssen, M. L., Oyen, W. J., Dijkgraaf, I., Tumor targeting with radiolabeled (v) (3) integrin binding peptides in a nude mouse model (2002) Cancer Res, 62, pp. 6146-6151
Beer, A. J., Grosu, A. -L., Carlsen, J., Kolk, A., Sarbia, M., Stangier, I., Watzlowik, P., Schwaiger, M., [18F] Galacto-RGD positron emission tomography for imaging of v 3 expression on the neovasculature in patients with squamous cell carcinoma of the head and neck (2007) Clinical Cancer Research, 13 (22), pp. 6610-6616. , http: //clincancerres. aacrjournals. org/cgi/reprint/13/22/6610, DOI 10. 1158/1078-0432. CCR-07-0528
Blystone, S. D., Lindberg, F. P., LaFlamme, S. E., Brown, E. J., Integrin 3 cytoplasmic tail is necessary and sufficient for regulation of 5 1 phagocytosis by v 3 and integrin-associated protein (1995) J Cell Biol, 130, pp. 745-754
Beer, A. J., Schwaiger, M., Imaging of integrin v 3 expression (2008) Cancer Metastasis Rev, 27, pp. 631-644
Goodman, S. L., Holzemann, G., Sulyok, G. A., Kessler, H., Nanomolar small molecule inhibitors for v () 6, v () 5, and v () 3 integrins (2002) J Med Chem, 45, pp. 1045-1051
Li, Z. B., Chen, K., Chen, X., (68) Ga-labeled multimeric RGD peptides for microPET imaging of integrin (v) (3) expression (2008) Eur J Nucl Med Mol Imaging, 35, pp. 1100-1108
Nabors, L. B., Mikkelsen, T., Rosenfeld, S. S., Hochberg, F., Akella, N. S., Fisher, J. D., Cloud, G. A., Grossman, S. A., Phase I and correlative biology study of cilengitide in patients with recurrent malignant glioma (2007) Journal of Clinical Oncology, 25 (13), pp. 1651-1657. , DOI 10. 1200/JCO. 2006. 06. 6514
Mizejewski, G. J., Role of integrins in cancer: Survey of expression patterns (1999) Proceedings of the Society for Experimental Biology and Medicine, 222 (2), pp. 124-138
Burvenich, I. J., Schoonooghe, S., Blanckaert, P., Biodistribution and planar camera imaging of (123) I- and (131) I-labeled F (ab') (2) and Fab fragments of monoclonal antibody 14C5 in nude mice bearing an A549 lung tumor (2007) Nucl Med Biol, 34, pp. 257-265
Imaging of αvβ3 expression by a bifunctional chimeric RGD peptide not cross-reacting with α vβ5