Liver fat in obesity: role of type 2 diabetes mellitus and adipose tissue distribution (386 views)
Eur J Clin Invest (ISSN: 0014-2972, 1365-2362, 0014-2972linking), 2011 Jan; 41(1): 39-44.
Export to BibTeX Export to EndNote
Paper type: Letter, Journal Article,
Impact factor: 3.018, 5-year impact factor: 2.797
Url: http://www.scopus.com/inward/record.url?eid=2-s2.0-0022135321&partnerID=40&md5=bd8bcc7356106c9be31064fb180f138b
Keywords: Female, Human, Letter, Liver Disease, Obesity, Adipose Tissue Physiopathology, Adult, Aged, Blood Glucose Metabolism, Body Mass Index, Case-Control Studies, Diabetes Mellitus, Type 2 Blood Physiopathology, Fatty Liver Physiopathology, Glucose Clamp Technique, Insulin Blood, Insulin Resistance Physiology, Intra-Abdominal Fat Metabolism Physiopathology, Middle Aged, Obesity Blood Physiopathology, Triglycerides Blood Metabolism, Fat Distribution, Insulin-Resistance, Liver Fat, Subcutaneous Fat, Type 2 Diabetes, Hemoglobin A1c, Metformin, Triacylglycerol, Article, Body Fat Distribution, Clinical Article, Controlled Study, Glycemic Control, Hyperinsulinemia, Insulin Sensitivity, Intraabdominal Fat, Non Insulin Dependent Diabetes Mellitus, Nuclear Magnetic Resonance Imaging, Priority Journal, Proton Nuclear Magnetic Resonance, Waist Circumference,
Affiliations:
*** IBB - CNR ***
Department of Medicine, University of Naples, Naples, Italy
Department of Metabolic Diseases, University of Naples, Naples, Italy
Department of Gastroenterology, University of Naples, Naples, Italy
Department of Clinical and Experimental Medicine, Federico II University, Naples, Italy.
Institute of Biostructure and Bioimage, National Research Council, Naples, Italy
SDN Foundation, Institute of Diagnostic and Nuclear Development, Naples, Italy
Institute of Food Sciences, National Research Council, Avellino, Italy
Department of Biomorphological and Functional Science, Federico II University, Naples, Italy
References:
Bellentani, S., Saccoccio, G., Masutti, F., Croce, L.S., Brandi, G., Sasso, F., Prevalence of and risk factors for hepatic steatosis in Northern Italy (2000) Ann Intern Med, 132, pp. 112-11
Luyckx, F.H., Desaive, C., Thiry, A., Dewe, W., Scheen, A.J., Gielen, J.E., Liver abnormalities in severely obese subjects: effect of drastic weight loss after gastroplasty (1998) Int J Obes Relat Metab Disord, 22, pp. 222-226
Gastaldelli, A., Cusi, K., Pettiti, M., Hardies, J., Miyazaki, Y., Berria, R., Relationship between hepatic/visceral fat and hepatic insulin resistance in nondiabetic and type 2 diabetic subjects (2007) Gastroenterology, 133, pp. 496-506
Bugianesi, E., McCullough, A.J., Marchesini, G., Insulin resistance: a metabolic pathway to chronic liver disease (2005) Hepatology, 42, pp. 987-1000
Cnop, M., Landchild, M.J., Vidal, J., Havel, P.J., Knowles, N.G., Carr, D.R., The concurrent accumulation of intra-abdominal and subcutaneous fat explains the association between insulin resistance and plasma leptin concentrations: distinct metabolic effects of two fat compartments (2002) Diabetes, 51, pp. 1005-1015
Ross, R., Aru, J., Freeman, J., Hudson, R., Janssen, I., Abdominal adiposity and insulin resistance in obese men (2002) Am J Physiol Endocrinol Metab, 282, pp. E657-E663
Marchesini, G., Brizi, M., Morselli-Labate, A.M., Bianchi, G., Bugianesi, E., McCullough, A.J., Association of nonalcoholic fatty liver disease with insulin resistance (1999) Am J Med, 107, pp. 450-455
Seppala-Lindroos, A., Vehkavaara, S., Hakkinen, A.M., Goto, T., Westerbacka, J., Sovijarvi, A., Fat accumulation in the liver is associated with defects in insulin suppression of glucose production and serum free fatty acids independent of obesity in normal men (2002) J Clin Endocrinol Metab, 87, pp. 3023-3028
Venturi, C., Zoppini, G., Zamboni, C., Muggeo, M., Insulin sensitivity and hepatic steatosis in obese subjects with normal glucose tolerance (2004) Nutr Metab Cardiovasc Dis, 14, pp. 200-204
Silverman, J.F., O'Brien, K.F., Long, S., Leggett, N., Khazanie, P.G., Pories, W.J., Liver pathology in morbidly obese patients with and without diabetes (1990) Am J Gastroenterol, 85, pp. 1349-1355
Kelley, D.E., McKolanis, T.M., Hegazi, R.A., Kuller, L.H., Kalhan, S.C., Fatty liver in type 2 diabetes mellitus: relation to regional adiposity, fatty acids, and insulin resistance (2003) Am J Physiol Endocrinol Metab, 285, pp. E906-E916
Kotronen, A., Juurinen, L., Hakkarainen, A., Westerbacka, J., Corner, A., Bergholm, R., Liver fat is increased in type 2 diabetic patients and underestimated by serum alanine aminotransferase compared with equally obese nondiabetic subjects (2008) Diabetes Care, 31, pp. 165-169
Gallagher, D., Kelley, D.E., Yim, J.E., Spence, N., Albu, J., Boxt, L., Adipose tissue distribution is different in type 2 diabetes (2009) Am J Clin Nutr, 89, pp. 807-814
Longo, R., Pollesello, P., Ricci, C., Masutti, F., Kvam, B.J., Bercich, L., Proton MR spectroscopy in quantitative in vivo determination of fat content in human liver steatosis (1995) J Magn Reson Imaging, 5, pp. 281-285
Longo, R., Ricci, C., Masutti, F., Vidimari, R., Croce, L.S., Bercich, L., Fatty infiltration of the liver. Quantification by 1H localized magnetic resonance spectroscopy and comparison with computed tomography (1993) Invest Radiol, 28, pp. 297-302
Ryysy, L., Hakkinen, A.M., Goto, T., Vehkavaara, S., Westerbacka, J., Halavaara, J., Hepatic fat content and insulin action on free fatty acids and glucose metabolism rather than insulin absorption are associated with insulin requirements during insulin therapy in type 2 diabetic patients (2000) Diabetes, 49, pp. 749-758
DeFronzo, R.A., Tobin, J.D., Andres, R., Glucose clamp technique: a method for quantifying insulin secretion and resistance (1979) Am J Physiol, 237, pp. E214-E223
Palmeira, C.M., Rolo, A.P., Berthiaume, J., Bjork, J.A., Wallace, K.B., Hyperglycemia decreases mitochondrial function: the regulatory role of mitochondrial biogenesis (2007) Toxicol Appl Pharmacol, 225, pp. 214-220
Caldwell, S.H., Swerdlow, R.H., Khan, E.M., Iezzoni, J.C., Hespenheide, E.E., Parks, J.K., Mitochondrial abnormalities in non-alcoholic steatohepatitis (1999) J Hepatol, 31, pp. 430-434
Demeilliers, C., Maisonneuve, C., Grodet, A., Mansouri, A., Nguyen, R., Tinel, M., Impaired adaptive resynthesis and prolonged depletion of hepatic mitochondrial DNA after repeated alcohol binges in mice (2002) Gastroenterology, 123, pp. 1278-1290
Bugianesi, E., Gastaldelli, A., Vanni, E., Gambino, R., Cassader, M., Baldi, S., Insulin resistance in non-diabetic patients with non-alcoholic fatty liver disease: sites and mechanisms (2005) Diabetologia, 48, pp. 634-642
Korenblat, K.M., Fabbrini, E., Mohammed, B.S., Klein, S., Liver, muscle, and adipose tissue insulin action is directly related to intrahepatic triglyceride content in obese subjects (2008) Gastroenterology, 134, pp. 1369-1375
Kotronen, A., Westerbacka, J., Bergholm, R., Pietilainen, K.H., Yki-Jarvinen, H., Liver fat in the metabolic syndrome (2007) J Clin Endocrinol Metab, 92, pp. 3490-3497
Tushuizen, M.E., Bunck, M.C., Pouwels, P.J., Bontemps, S., Mari, A., Diamant, M., Lack of association of liver fat with model parameters of beta-cell function in men with impaired glucose tolerance and type 2 diabetes (2008) Eur J Endocrinol, 159, pp. 251-257
Weyer, C., Foley, J.E., Bogardus, C., Tataranni, P.A., Pratley, R.E., Enlarged subcutaneous abdominal adipocyte size, but not obesity itself, predicts type II diabetes independent of insulin resistance (2000) Diabetologia, 43, pp. 1498-1506
Dubois, S.G., Heilbronn, L.K., Smith, S.R., Albu, J.B., Kelley, D.E., Ravussin, E., Decreased expression of adipogenic genes in obese subjects with type 2 diabetes (2006) Obesity (Silver Spring), 14, pp. 1543-1552
Kim, J.Y., Van De Wall, E., Laplante, M., Azzara, A., Trujillo, M.E., Hofmann, S.M., Obesity-associated improvements in metabolic profile through expansion of adipose tissue (2007) J Clin Invest, 117, pp. 2621-2637
Luyckx, F. H., Desaive, C., Thiry, A., Dewe, W., Scheen, A. J., Gielen, J. E., Liver abnormalities in severely obese subjects: effect of drastic weight loss after gastroplasty (1998) Int J Obes Relat Metab Disord, 22, pp. 222-226
Silverman, J. F., O'Brien, K. F., Long, S., Leggett, N., Khazanie, P. G., Pories, W. J., Liver pathology in morbidly obese patients with and without diabetes (1990) Am J Gastroenterol, 85, pp. 1349-1355
Kelley, D. E., McKolanis, T. M., Hegazi, R. A., Kuller, L. H., Kalhan, S. C., Fatty liver in type 2 diabetes mellitus: relation to regional adiposity, fatty acids, and insulin resistance (2003) Am J Physiol Endocrinol Metab, 285, pp. E906-E916
DeFronzo, R. A., Tobin, J. D., Andres, R., Glucose clamp technique: a method for quantifying insulin secretion and resistance (1979) Am J Physiol, 237, pp. E214-E223
Palmeira, C. M., Rolo, A. P., Berthiaume, J., Bjork, J. A., Wallace, K. B., Hyperglycemia decreases mitochondrial function: the regulatory role of mitochondrial biogenesis (2007) Toxicol Appl Pharmacol, 225, pp. 214-220
Caldwell, S. H., Swerdlow, R. H., Khan, E. M., Iezzoni, J. C., Hespenheide, E. E., Parks, J. K., Mitochondrial abnormalities in non-alcoholic steatohepatitis (1999) J Hepatol, 31, pp. 430-434
Korenblat, K. M., Fabbrini, E., Mohammed, B. S., Klein, S., Liver, muscle, and adipose tissue insulin action is directly related to intrahepatic triglyceride content in obese subjects (2008) Gastroenterology, 134, pp. 1369-1375
Tushuizen, M. E., Bunck, M. C., Pouwels, P. J., Bontemps, S., Mari, A., Diamant, M., Lack of association of liver fat with model parameters of beta-cell function in men with impaired glucose tolerance and type 2 diabetes (2008) Eur J Endocrinol, 159, pp. 251-257
Dubois, S. G., Heilbronn, L. K., Smith, S. R., Albu, J. B., Kelley, D. E., Ravussin, E., Decreased expression of adipogenic genes in obese subjects with type 2 diabetes (2006) Obesity (Silver Spring), 14, pp. 1543-1552
Kim, J. Y., Van De Wall, E., Laplante, M., Azzara, A., Trujillo, M. E., Hofmann, S. M., Obesity-associated improvements in metabolic profile through expansion of adipose tissue (2007) J Clin Invest, 117, pp. 2621-2637
Eur J Clin Invest (ISSN: 0014-2972, 1365-2362, 0014-2972linking), 2011 Jan; 41(1): 39-44.
Export to BibTeX Export to EndNote
Paper type: Letter, Journal Article,
Impact factor: 3.018, 5-year impact factor: 2.797
Url: http://www.scopus.com/inward/record.url?eid=2-s2.0-0022135321&partnerID=40&md5=bd8bcc7356106c9be31064fb180f138b
Keywords: Female, Human, Letter, Liver Disease, Obesity, Adipose Tissue Physiopathology, Adult, Aged, Blood Glucose Metabolism, Body Mass Index, Case-Control Studies, Diabetes Mellitus, Type 2 Blood Physiopathology, Fatty Liver Physiopathology, Glucose Clamp Technique, Insulin Blood, Insulin Resistance Physiology, Intra-Abdominal Fat Metabolism Physiopathology, Middle Aged, Obesity Blood Physiopathology, Triglycerides Blood Metabolism, Fat Distribution, Insulin-Resistance, Liver Fat, Subcutaneous Fat, Type 2 Diabetes, Hemoglobin A1c, Metformin, Triacylglycerol, Article, Body Fat Distribution, Clinical Article, Controlled Study, Glycemic Control, Hyperinsulinemia, Insulin Sensitivity, Intraabdominal Fat, Non Insulin Dependent Diabetes Mellitus, Nuclear Magnetic Resonance Imaging, Priority Journal, Proton Nuclear Magnetic Resonance, Waist Circumference,
Affiliations:
*** IBB - CNR ***
Department of Medicine, University of Naples, Naples, Italy
Department of Metabolic Diseases, University of Naples, Naples, Italy
Department of Gastroenterology, University of Naples, Naples, Italy
Department of Clinical and Experimental Medicine, Federico II University, Naples, Italy.
Institute of Biostructure and Bioimage, National Research Council, Naples, Italy
SDN Foundation, Institute of Diagnostic and Nuclear Development, Naples, Italy
Institute of Food Sciences, National Research Council, Avellino, Italy
Department of Biomorphological and Functional Science, Federico II University, Naples, Italy
References:
Bellentani, S., Saccoccio, G., Masutti, F., Croce, L.S., Brandi, G., Sasso, F., Prevalence of and risk factors for hepatic steatosis in Northern Italy (2000) Ann Intern Med, 132, pp. 112-11
Luyckx, F.H., Desaive, C., Thiry, A., Dewe, W., Scheen, A.J., Gielen, J.E., Liver abnormalities in severely obese subjects: effect of drastic weight loss after gastroplasty (1998) Int J Obes Relat Metab Disord, 22, pp. 222-226
Gastaldelli, A., Cusi, K., Pettiti, M., Hardies, J., Miyazaki, Y., Berria, R., Relationship between hepatic/visceral fat and hepatic insulin resistance in nondiabetic and type 2 diabetic subjects (2007) Gastroenterology, 133, pp. 496-506
Bugianesi, E., McCullough, A.J., Marchesini, G., Insulin resistance: a metabolic pathway to chronic liver disease (2005) Hepatology, 42, pp. 987-1000
Cnop, M., Landchild, M.J., Vidal, J., Havel, P.J., Knowles, N.G., Carr, D.R., The concurrent accumulation of intra-abdominal and subcutaneous fat explains the association between insulin resistance and plasma leptin concentrations: distinct metabolic effects of two fat compartments (2002) Diabetes, 51, pp. 1005-1015
Ross, R., Aru, J., Freeman, J., Hudson, R., Janssen, I., Abdominal adiposity and insulin resistance in obese men (2002) Am J Physiol Endocrinol Metab, 282, pp. E657-E663
Marchesini, G., Brizi, M., Morselli-Labate, A.M., Bianchi, G., Bugianesi, E., McCullough, A.J., Association of nonalcoholic fatty liver disease with insulin resistance (1999) Am J Med, 107, pp. 450-455
Seppala-Lindroos, A., Vehkavaara, S., Hakkinen, A.M., Goto, T., Westerbacka, J., Sovijarvi, A., Fat accumulation in the liver is associated with defects in insulin suppression of glucose production and serum free fatty acids independent of obesity in normal men (2002) J Clin Endocrinol Metab, 87, pp. 3023-3028
Venturi, C., Zoppini, G., Zamboni, C., Muggeo, M., Insulin sensitivity and hepatic steatosis in obese subjects with normal glucose tolerance (2004) Nutr Metab Cardiovasc Dis, 14, pp. 200-204
Silverman, J.F., O'Brien, K.F., Long, S., Leggett, N., Khazanie, P.G., Pories, W.J., Liver pathology in morbidly obese patients with and without diabetes (1990) Am J Gastroenterol, 85, pp. 1349-1355
Kelley, D.E., McKolanis, T.M., Hegazi, R.A., Kuller, L.H., Kalhan, S.C., Fatty liver in type 2 diabetes mellitus: relation to regional adiposity, fatty acids, and insulin resistance (2003) Am J Physiol Endocrinol Metab, 285, pp. E906-E916
Kotronen, A., Juurinen, L., Hakkarainen, A., Westerbacka, J., Corner, A., Bergholm, R., Liver fat is increased in type 2 diabetic patients and underestimated by serum alanine aminotransferase compared with equally obese nondiabetic subjects (2008) Diabetes Care, 31, pp. 165-169
Gallagher, D., Kelley, D.E., Yim, J.E., Spence, N., Albu, J., Boxt, L., Adipose tissue distribution is different in type 2 diabetes (2009) Am J Clin Nutr, 89, pp. 807-814
Longo, R., Pollesello, P., Ricci, C., Masutti, F., Kvam, B.J., Bercich, L., Proton MR spectroscopy in quantitative in vivo determination of fat content in human liver steatosis (1995) J Magn Reson Imaging, 5, pp. 281-285
Longo, R., Ricci, C., Masutti, F., Vidimari, R., Croce, L.S., Bercich, L., Fatty infiltration of the liver. Quantification by 1H localized magnetic resonance spectroscopy and comparison with computed tomography (1993) Invest Radiol, 28, pp. 297-302
Ryysy, L., Hakkinen, A.M., Goto, T., Vehkavaara, S., Westerbacka, J., Halavaara, J., Hepatic fat content and insulin action on free fatty acids and glucose metabolism rather than insulin absorption are associated with insulin requirements during insulin therapy in type 2 diabetic patients (2000) Diabetes, 49, pp. 749-758
DeFronzo, R.A., Tobin, J.D., Andres, R., Glucose clamp technique: a method for quantifying insulin secretion and resistance (1979) Am J Physiol, 237, pp. E214-E223
Palmeira, C.M., Rolo, A.P., Berthiaume, J., Bjork, J.A., Wallace, K.B., Hyperglycemia decreases mitochondrial function: the regulatory role of mitochondrial biogenesis (2007) Toxicol Appl Pharmacol, 225, pp. 214-220
Caldwell, S.H., Swerdlow, R.H., Khan, E.M., Iezzoni, J.C., Hespenheide, E.E., Parks, J.K., Mitochondrial abnormalities in non-alcoholic steatohepatitis (1999) J Hepatol, 31, pp. 430-434
Demeilliers, C., Maisonneuve, C., Grodet, A., Mansouri, A., Nguyen, R., Tinel, M., Impaired adaptive resynthesis and prolonged depletion of hepatic mitochondrial DNA after repeated alcohol binges in mice (2002) Gastroenterology, 123, pp. 1278-1290
Bugianesi, E., Gastaldelli, A., Vanni, E., Gambino, R., Cassader, M., Baldi, S., Insulin resistance in non-diabetic patients with non-alcoholic fatty liver disease: sites and mechanisms (2005) Diabetologia, 48, pp. 634-642
Korenblat, K.M., Fabbrini, E., Mohammed, B.S., Klein, S., Liver, muscle, and adipose tissue insulin action is directly related to intrahepatic triglyceride content in obese subjects (2008) Gastroenterology, 134, pp. 1369-1375
Kotronen, A., Westerbacka, J., Bergholm, R., Pietilainen, K.H., Yki-Jarvinen, H., Liver fat in the metabolic syndrome (2007) J Clin Endocrinol Metab, 92, pp. 3490-3497
Tushuizen, M.E., Bunck, M.C., Pouwels, P.J., Bontemps, S., Mari, A., Diamant, M., Lack of association of liver fat with model parameters of beta-cell function in men with impaired glucose tolerance and type 2 diabetes (2008) Eur J Endocrinol, 159, pp. 251-257
Weyer, C., Foley, J.E., Bogardus, C., Tataranni, P.A., Pratley, R.E., Enlarged subcutaneous abdominal adipocyte size, but not obesity itself, predicts type II diabetes independent of insulin resistance (2000) Diabetologia, 43, pp. 1498-1506
Dubois, S.G., Heilbronn, L.K., Smith, S.R., Albu, J.B., Kelley, D.E., Ravussin, E., Decreased expression of adipogenic genes in obese subjects with type 2 diabetes (2006) Obesity (Silver Spring), 14, pp. 1543-1552
Kim, J.Y., Van De Wall, E., Laplante, M., Azzara, A., Trujillo, M.E., Hofmann, S.M., Obesity-associated improvements in metabolic profile through expansion of adipose tissue (2007) J Clin Invest, 117, pp. 2621-2637
Luyckx, F. H., Desaive, C., Thiry, A., Dewe, W., Scheen, A. J., Gielen, J. E., Liver abnormalities in severely obese subjects: effect of drastic weight loss after gastroplasty (1998) Int J Obes Relat Metab Disord, 22, pp. 222-226
Silverman, J. F., O'Brien, K. F., Long, S., Leggett, N., Khazanie, P. G., Pories, W. J., Liver pathology in morbidly obese patients with and without diabetes (1990) Am J Gastroenterol, 85, pp. 1349-1355
Kelley, D. E., McKolanis, T. M., Hegazi, R. A., Kuller, L. H., Kalhan, S. C., Fatty liver in type 2 diabetes mellitus: relation to regional adiposity, fatty acids, and insulin resistance (2003) Am J Physiol Endocrinol Metab, 285, pp. E906-E916
DeFronzo, R. A., Tobin, J. D., Andres, R., Glucose clamp technique: a method for quantifying insulin secretion and resistance (1979) Am J Physiol, 237, pp. E214-E223
Palmeira, C. M., Rolo, A. P., Berthiaume, J., Bjork, J. A., Wallace, K. B., Hyperglycemia decreases mitochondrial function: the regulatory role of mitochondrial biogenesis (2007) Toxicol Appl Pharmacol, 225, pp. 214-220
Caldwell, S. H., Swerdlow, R. H., Khan, E. M., Iezzoni, J. C., Hespenheide, E. E., Parks, J. K., Mitochondrial abnormalities in non-alcoholic steatohepatitis (1999) J Hepatol, 31, pp. 430-434
Korenblat, K. M., Fabbrini, E., Mohammed, B. S., Klein, S., Liver, muscle, and adipose tissue insulin action is directly related to intrahepatic triglyceride content in obese subjects (2008) Gastroenterology, 134, pp. 1369-1375
Tushuizen, M. E., Bunck, M. C., Pouwels, P. J., Bontemps, S., Mari, A., Diamant, M., Lack of association of liver fat with model parameters of beta-cell function in men with impaired glucose tolerance and type 2 diabetes (2008) Eur J Endocrinol, 159, pp. 251-257
Dubois, S. G., Heilbronn, L. K., Smith, S. R., Albu, J. B., Kelley, D. E., Ravussin, E., Decreased expression of adipogenic genes in obese subjects with type 2 diabetes (2006) Obesity (Silver Spring), 14, pp. 1543-1552
Kim, J. Y., Van De Wall, E., Laplante, M., Azzara, A., Trujillo, M. E., Hofmann, S. M., Obesity-associated improvements in metabolic profile through expansion of adipose tissue (2007) J Clin Invest, 117, pp. 2621-2637
Liver fat in obesity: role of type 2 diabetes mellitus and adipose tissue distribution
BACKGROUND: Fatty liver is commonly associated with insulin-resistant conditions, often related to increased abdominal visceral fat. Our objective was to elucidate the specific roles of obesity, type 2 diabetes mellitus, insulin-resistance and abdominal fat distribution.; MATERIALS AND METHODS: The study population comprised 13 diabetic obese (DO), 10 nondiabetic obese (NDO), and nine normal-weight control (C) men aged 28-65years, with normal plasma triglyceride levels. DO were in good glycaemic control (HbA1c = 6·8 ± 0·8%) (M ± SD) with diet (n = 8) or diet + metformin (n = 5). Liver fat content was measured by (1) H-magnetic resonance spectroscopy, abdominal fat distribution by magnetic resonance imaging and insulin sensitivity by hyperinsulinaemic euglycaemic clamp.; RESULTS: DO and NDO subjects had similar whole-body insulin resistance, BMI and waist circumference, higher than those of C subjects (P < 0·001). DO had more liver fat (11·9 ± 7·0%) than NDO (5·2 ± 2·8%, P < 0·05) and C (1·6 ± 1·0%, P < 0·001). Abdominal fat was greater in DO and NDO than in C (visceral: DO 3184 ± 843, NDO 2843 ± 1378 vs. C 1212 ± 587 cm(3), P < 0·001; subcutaneous: DO 4029 ± 362, NDO 5197 ± 1398 vs. C 2312 ± 626 cm(3), P < 0·001), visceral fat being not significantly different between the two obese groups, and subcutaneous fat significantly less in DO than in NDO (P < 0·05).; CONCLUSIONS: Type 2 diabetes is associated with increased fat accumulation in the liver, independent of obesity and whole-body insulin resistance. The increased liver fat in DO patients may be part of an altered regional fat distribution that includes an inadequate subcutaneous fat storing capacity, rather than simply being a consequence of increased abdominal visceral content. 2010 The Authors. European Journal of Clinical Investigation 2010 Stichting European Society for Clinical Investigation Journal Foundation.
BACKGROUND: Fatty liver is commonly associated with insulin-resistant conditions, often related to increased abdominal visceral fat. Our objective was to elucidate the specific roles of obesity, type 2 diabetes mellitus, insulin-resistance and abdominal fat distribution.; MATERIALS AND METHODS: The study population comprised 13 diabetic obese (DO), 10 nondiabetic obese (NDO), and nine normal-weight control (C) men aged 28-65years, with normal plasma triglyceride levels. DO were in good glycaemic control (HbA1c = 6·8 ± 0·8%) (M ± SD) with diet (n = 8) or diet + metformin (n = 5). Liver fat content was measured by (1) H-magnetic resonance spectroscopy, abdominal fat distribution by magnetic resonance imaging and insulin sensitivity by hyperinsulinaemic euglycaemic clamp.; RESULTS: DO and NDO subjects had similar whole-body insulin resistance, BMI and waist circumference, higher than those of C subjects (P < 0·001). DO had more liver fat (11·9 ± 7·0%) than NDO (5·2 ± 2·8%, P < 0·05) and C (1·6 ± 1·0%, P < 0·001). Abdominal fat was greater in DO and NDO than in C (visceral: DO 3184 ± 843, NDO 2843 ± 1378 vs. C 1212 ± 587 cm(3), P < 0·001; subcutaneous: DO 4029 ± 362, NDO 5197 ± 1398 vs. C 2312 ± 626 cm(3), P < 0·001), visceral fat being not significantly different between the two obese groups, and subcutaneous fat significantly less in DO than in NDO (P < 0·05).; CONCLUSIONS: Type 2 diabetes is associated with increased fat accumulation in the liver, independent of obesity and whole-body insulin resistance. The increased liver fat in DO patients may be part of an altered regional fat distribution that includes an inadequate subcutaneous fat storing capacity, rather than simply being a consequence of increased abdominal visceral content. 2010 The Authors. European Journal of Clinical Investigation 2010 Stichting European Society for Clinical Investigation Journal Foundation.
Liver fat in obesity: role of type 2 diabetes mellitus and adipose tissue distribution
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Liver fat in obesity: role of type 2 diabetes mellitus and adipose tissue distribution
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Impact Factor: 1.547
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Cernigliaro V, Peluso R, Zedda B, Silengo L, Tolosano E, Pellicano R, Altruda F, Fagoonee S
* Evolving Cell-Based and Cell-Free Clinical Strategies for Treating Severe Human Liver Diseases (116 views)
Cells (ISSN: 2073-4409linking, 2073-4409electronic), 2020 Feb 7; 9(2): N/D-N/D.
Impact Factor: 4.366
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Negri R, Trinchese G, Carbone F, Caprio MG, Stanzione G, Di Scala C, Micillo T, Perna F, Tarotto L, Gelzo M, Cavaliere G, Spagnuolo MI, Corso G, Mattace Raso G, Matarese G, Mollica MP, Greco L, Iorio R
* Randomised Clinical Trial: Calorie Restriction Regimen with Tomato Juice Supplementation Ameliorates Oxidative Stress and Preserves a Proper Immune Surveillance Modulating Mitochondrial Bioenergetics of T-Lymphocytes in Obese Children Affected by Non-Alcoholic Fatty Liver Disease (NAFLD) (98 views) (PDF 83 views)
J Clin Med (ISSN: 2077-0383linking, 2077-0383electronic), 2020 Jan 4; 9(1): N/D-N/D.
Impact Factor: 5.688
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Gandhi S, Marr K, Mancini M, Caprio MG, Jakimovski D, Chandra A, Hagemeier J, Hojnacki D, Kolb C, Weinstock-guttman B, Zivadinov R
* No association between variations in extracranial venous anatomy and clinical outcomes in multiple sclerosis patients over 5 years (175 views)
Bmc Neurol (ISSN: 1471-2377linking, 1471-2377electronic), 2019 Jun 11; 19(1): 121-121.
Impact Factor: 2.17
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Klisic A, Abenavoli L, Fagoonee S, Kavaric N, Kocic G, Ninic A
* Older age and HDL-cholesterol as independent predictors of liver fibrosis assessed by BARD score (156 views)
Hepatology (ISSN: 0026-4806linking, 1827-1669electronic), 2019 Jun; 110(3): 191-198.
Impact Factor: 2.863
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Durazzo M, Ponzo E, Bonetto S, Fagoonee S, Pellicano R
* Liver diseases in the elderly (344 views)
Hepatology (ISSN: 0026-4806linking, 1827-1669electronic), 2018 Oct 11; 110(1): 35-51.
Impact Factor: 2.863
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Testino G, Leone S, Fagoonee S, Pellicano R
* The role of adenosyl-methionine in alcoholic liver disease and intrahepatic cholestasis (120 views)
Minerva Gastroenterol Dietol (ISSN: 1827-1642electronic, 1121-421xlinking), 2018 Sep; 64(3): 187-189.
Impact Factor: 1.29
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Mancini M, Summers P, Faita F, Brunetto MR, Callea F, De Nicola A, Di Lascio N, Farinati F, Gastaldelli A, Gridelli B, Mirabelli P, Neri E, Salvadori PA, Rebelos E, Tiribelli C, Valenti L, Salvatore M, Bonino F
* Digital liver biopsy: Bio-imaging of fatty liver for translational and clinical research (695 views) (PDF 135 views)
World J Hepatol (ISSN: 1948-5182print, 1948-5182electronic), 2018 Feb 27; 10(2): 231-245.
Impact Factor: 0.78
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Di Lascio N, Avigo C, Salvati A, Martini N, Ragucci M, Monti S, Prinster A, Chiappino D, Mancini M, D'Elia D, Ghiadoni L, Bonino F, Brunetto MR, Faita F
* Steato-Score: Non-Invasive Quantitative Assessment of Liver Fat by Ultrasound Imaging (350 views)
Ultrasound Med Biol (ISSN: 0301-5629, 0301-5629linking), 2018; 44(8): 1585-1596.
Impact Factor: 2.494
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Ricco G, Cavallone D, Cosma C, Caviglia GP, Oliveri F, Biasiolo A, Abate ML, Plebani M, Smedile A, Bonino F, Pontisso P, Brunetto MR
* Impact of etiology of chronic liver disease on hepatocellular carcinoma biomarkers (484 views)
Cancer Biomark (ISSN: 1574-0153, 1574-0153linking), 2017 Dec 15; 21(3): 603-612.
Impact Factor: 2.392
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Mancini M, Salomone Megna A, Ragucci M, De Luca M, Marino Marsilia G, Nardone G, Coccoli P, Prinster A, Mannelli L, Vergara E, Monti S, Liuzzi R, Incoronato M
* Reproducibility of shear wave elastography (SWE) in patients with chronic liver disease (218 views)
Plosone (ISSN: 1932-6203, 1932-6203electronic, 1932-6203linking), 2017 Oct 12; 12(10): e0185391-e0185391.
Impact Factor: 2.766
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Caprio MG, Marr K, Gandhi S, Jakimovski D, Hagemeier J, Weinstock-guttman B, Zivadinov R, Mancini M
* Centralized and local color Doppler ultrasound reading agreement for diagnosis of the chronic cerebrospinal venous insufficiency in patients with Multiple Sclerosis (223 views)
Curr Neurovasc Res (ISSN: 1567-2026, 1567-2026linking), 2017 Jul 17; 14(3): 266-273.
Impact Factor: 1.716
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Fagoonee S, Famulari ES, Silengo L, Camussi G, Altruda F
* Prospects for Adult Stem Cells in the Treatment of Liver Diseases (198 views)
Stem Cells Dev (ISSN: 1547-3287, 1547-3287linking), 2016 Sep 7; 25(20): 1471-1482.
Impact Factor: 3.562
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Pisani A, Sabbatini M, Imbriaco M, Riccio E, Rubis N, Prinster A, Perna A, Liuzzi R, Spinelli L, Santangelo M, Remuzzi G, Ruggenenti P
* Long-term Effects of Octreotide on Liver Volume in Patients With Polycystic Kidney and Liver Disease (263 views)
Clin Gastroenterol H (ISSN: 1542-3565), 2016 Feb 1; N/D: N/D-N/D.
Impact Factor: 7.398
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Petta S, Valenti L, Bugianesi E, Targher G, Bellentani S, Bonino F, Fargion S, Vanni E, Ferrannini E, Loguercio C, Lonardo A, Marra F, Mancini M, Miele L, Nobili V, Baroni GS, Alessandro F, Ballestri S, Brunetto MR, Coco B, Grieco A, Kondili L, Nascimbeni F, Prinster A, Romagnoli D, Taddei S, Vella S
* A "systems medicine" approach to the study of non-alcoholic fatty liver disease (370 views)
Dig Liver Dis (ISSN: 1590-8658, 1590-8658linking), 2016; 48(3): 333-342.
Impact Factor: 3.061
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Ribaldone DG, Garavagno M, Pellicano R, Bresso F, Fagoonee S, David E, Sapone N, Bonagura AG, Resegotti A, Astegiano M
* Prevalence and prognostic value of hepatic histological alterations in patients with Crohn's disease (286 views)
Scand J Gastroentero (ISSN: 0036-5521, 0036-5521linking), 2015; 50(12): 1463-1468.
Impact Factor: 2.199
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Salvatore E, Tedeschi E, Mollica C, Vicidomini C, Varrone A, Coda ARD, Brunetti A, Salvatore M, De Michele G, Filla A, Pappata S
* Supratentorial and infratentorial damage in spinocerebellar ataxia 2: a diffusion-weighted MRI study (344 views)
Mov Disord (ISSN: 0885-3185, 1531-8257, 0885-3185linking), 2014 May; 29(6): 780-786.
Impact Factor: 5.68
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Mancini M, Lanzillo R, Liuzzi R, Di Donato O, Ragucci M, Monti S, Salvatore E, Morra VB, Salvatore M
* Internal jugular vein blood flow in multiple sclerosis patients and matched controls (347 views) (PDF 199 views)
Plosone (ISSN: 1932-6203, 1932-6203electronic, 1932-6203linking), 2014 Mar 27; 9(3): e92730-e92730.
Impact Factor: 3.234
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Storto G, Gallicchio R, Maddalena F, Pellegrino T, Petretta M, Fiumara G, Cuocolo A
* Estimation of coronary flow reserve by sestamibi imaging in patients with mild hypertension and normal coronary arteries (307 views)
Q J Nucl Med Mol Im (ISSN: 1824-4785, 1824-4478, 1827-1936), 2014 Mar 14; 59(3): 336-341.
Impact Factor: 2.033
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Molino I, Cavaliere C, Salvatore E, Quarantelli M, Colucci L, Fasanaro AM
* Is anterior communicating artery syndrome related to fornix lesions? (266 views)
J Alzheimers Dis (ISSN: 1387-2877, 1387-2877linking), 2014; 42Suppl3: S199-S199.
Impact Factor: 4.151
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Comi G, Battaglia MA, Bertolotto A, Del Sette M, Ghezzi A, Malferrari G, Salvetti M, Sormani MP, Tesio L, Stolz E, Zaratin P, Mancardi G, Mancini M
* Observational case-control study of the prevalence of chronic cerebrospinal venous insufficiency in multiple sclerosis: results from the CoSMo study (255 views)
Mult Scler (ISSN: 1477-0970, 1352-4585, 1352-4585linking), 2013 Oct; 19(11): 1508-1517.
Impact Factor: 4.863
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Vitale M, Luongo D, Naviglio D, Bozzetto L, Mirabella M, Rivieccio AM, Giacco A, Rivellese AA
* Trans fatty acids consumption in type 1 diabetic patients: evaluation by dietary records and measurement in serum phospholipids (365 views)
Acta Diabetol (ISSN: 0940-5429, 1432-5233electronic), 2013 Aug; 50(4): 651-654.
Impact Factor: 3.679
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Pasanisi F, Pace L, Fonti R, Marra M, Sgambati D, De Caprio C, De Filippo E, Vaccaro A, Salvatore M, Contaldo F
* Evidence of brown fat activity in constitutional leanness (480 views)
J Clin Endocrinol Metab (ISSN: 1945-7197, 0021-972x, 0021-972xlinking), 2013 Mar; 98(3): 1214-1218.
Impact Factor: 6.31
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Lanzillo R, Mancini M, Liuzzi R, Di Donato O, Salvatore E, Maglio V, Vacca G, Amato L, D'Anna G, Brunetti A, Brescia Morra V
* Chronic cerebrospinal venous insufficiency in multiple sclerosis: a highly prevalent age-dependent phenomenon (455 views)
Bmc Neurol (ISSN: 1471-2377, 1471-2377linking), 2013 Feb 13; 13: 20-20.
Impact Factor: 2.486
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Erro R, Pappata S, Amboni M, Vicidomini C, Longo K, Santangelo G, Picillo M, Vitale C, Moccia M, Giordano F, Brunetti A, Pellecchia MT, Salvatore M, Barone P
* Anxiety is associated with striatal dopamine transporter availability in newly diagnosed untreated Parkinson's disease patients (466 views)
Parkinsonism Relat D (ISSN: 1873-5126, 1353-8020, 1873-5126electronic), 2012 Nov; 18(9): 1034-1038.
Impact Factor: 3.274
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Marciano C, Galderisi M, Gargiulo P, Acampa W, D'Amore C, Esposito R, Capasso E, Savarese G, Casaretti L, Lo Iudice F, Esposito G, Rengo G, Leosco D, Cuocolo A, Perrone-Filardi P
* Effects of type 2 diabetes mellitus on coronary microvascular function and myocardial perfusion in patients without obstructive coronary artery disease (536 views)
Eur J Nucl Med (ISSN: 1619-7070, 1619-7089, 0340-6997), 2012 Jul; 39(7): 1199-1206.
Impact Factor: 5.114
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Pier PM
* RE: Imaging Features of Hepato-Splenic Amyloidosis at PET/CT (283 views)
Korean Journal Of Radiology (ISSN: 1229-6929), 2012 May; 13(3): 368-369.
Impact Factor: 1.555
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Mancini M, Morra VB, Di Donato O, Maglio V, Lanzillo R, Liuzzi R, Salvatore E, Brunetti A, Iaccarino V, Salvatore M
* Multiple sclerosis: cerebral circulation time (384 views)
Radiology (ISSN: 1527-1315, 0033-8419, 1527-1315electronic), 2012 Mar; 262(3): 947-955.
Impact Factor: 6.339
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Lanzillo R, Di Somma C, Quarantelli M, Ventrella G, Gasperi M, Prinster A, Vacca G, Pivonello C, Orefice G, Colao A, Morra VB
* Insulin-like growth factor (IGF)-I and IGF-binding protein-3 serum levels in relapsing-remitting and secondary progressive multiple sclerosis patients (304 views)
Eur J Neurol (ISSN: 1351-5101, 1468-1331electronic, 1351-5101linking), 2011 Dec; 18(12): 1402-1406.
Impact Factor: 3.692
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Giacco R, Della Pepa G, Luongo D, Riccardi G
* Whole grain intake in relation to body weight: From epidemiological evidence to clinical trials (536 views)
Nutrition (ISSN: 0939-4753, 1590-3729electronic), 2011 Dec; 21(12): 901-908.
Impact Factor: 3.731
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Pappata S, Santangelo G, Aarsland D, Vicidomini C, Longo K, Bronnick K, Amboni M, Erro R, Vitale C, Caprio MG, Pellecchia MT, Brunetti A, De Michele G, Salvatore M, Barone P
* Mild cognitive impairment in drug-naive patients with PD is associated with cerebral hypometabolism (448 views)
Neurology (ISSN: 0028-3878, 1526-632x, 1526-632xelectronic), 2011 Oct 4; 77(14): 1357-1362.
Impact Factor: 8.312
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Dinacci D, Tessitore A, Russo AA, De Bonis ML, Lavorgna L, Picconi O, Sacco R, Bonavita S, Gallo A, Servillo G, Marcuccio L, Comerci M, Galletti P, Alfano B, Tedeschi G
* BDNF Val66Met polymorphism and brain volumes in multiple sclerosis (400 views) (PDF 230 views)
Neurol Sci (ISSN: 1590-1874, 1590-3478, 1590-1874linking), 2011 Feb; 32(1): 117-123.
Impact Factor: 1.315
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Pappata S, Varrone A, Vicidomini C, Milan G, De Falco C, Sansone V, Iavarone A, Comerci M, Loré E, Panico M, Quarantelli M, Postiglione A, Salvatore M
* SPECT imaging of GABAA/benzodiazepine receptors and cerebral perfusion in mild cognitive impairment (486 views)
Eur J Nucl Med (ISSN: 1619-7070, 1619-7089, 0340-6997), 2010 Jun; 37(6): 1156-1163.
Impact Factor: 5.036
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Galasso G, De Rosa R, Piscione F, Iaccarino G, Vosa C, Sorriento D, Piccolo R, Rapacciuolo A, Walsh K, Chiariello M
* Myocardial expression of FOXO3a-Atrogin-1 pathway in human heart failure (245 views)
Eur J Heart Fail European Journal Of Heart Failure (ISSN: 1388-9842), 2010; 12(12): 1290-1296.
Impact Factor: 4.512
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Coppola G, Fortunato D, Auricchio G, Mainolfi C, Operto FF, Signoriello G, Pascotto A, Salvatore M
* Bone mineral density in children, adolescents, and young adults with epilepsy (348 views)
Epilepsia (ISSN: 1528-1167, 0013-9580), 2009 Sep; 50(9): 2140-2146.
Impact Factor: 4.052
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Lanzillo R, Di Somma C, Quarantelli M, Gasperi M, Ventrella G, Prinster A, Vacca G, Orefice G, Colao A, Morra VB
* Serum levels of insulin like growth factor-1 and insulin like growth factor binding protein-3 in relapsing and secondary progressive multiple sclerosis (328 views)
Mult Scler (ISSN: 1352-4585, 1477-0970, 1352-4585linking), 2009 Sep; 15(9): 1402-1406.
Impact Factor: 3.279
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Masulli M, Mancini M, Liuzzi R, Daniele S, Mainenti PP, Vergara E, Genovese S, Salvatore M, Vaccaro O
* Measurement of the intrarenal arterial resistance index for the identification and prediction of diabetic nephropathy (561 views)
Nutrition (ISSN: 0939-4753, 1590-3729electronic, 0939-4753linking), 2009 Jun; 19(5): 358-364.
Impact Factor: 3.517
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Gentile I, Viola C, Graf M, Liuzzi R, Quarto M, Cerini R, Piazza M, Borgia G
* A simple noninvasive score predicts gastroesophageal varices in patients with chronic viral hepatitis (369 views)
J Clin Gastroenterol (ISSN: 0192-0790), 2009 Jan; 43(1): 81-87.
Impact Factor: 2.207
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Spinelli L, Nicolai E, Acampa W, Imbriaco M, Pisani A, Rao MA, Scopacasa F, Cianciaruso B, De Luca N, Cuocolo A
* Cardiac performance during exercise in patients with Fabry's disease (348 views)
Eur J Clin Invest (ISSN: 0014-2972, 1365-2362, 0014-2972linking), 2008 Dec; 38(12): 910-917.
Impact Factor: 2.784
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De Bonis S, Rendina D, Vargas G, Minno DD, Piedimonte V, Gallotta G, Postiglione A
* Predictors of In-Hospital and Long-Term Clinical Outcome in Elderly Patients with Massive Pulmonary Embolism Receiving Thrombolytic Therapy (316 views)
J Am Geriatr Soc (ISSN: 0002-8614), 2008 Dec; 56(12): 2273-2277.
Impact Factor: 3.805
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Varrone A, Sansone V, Pellecchia MT, Amboni M, Salvatore E, De Michele G, Filla A, Barone P, Pappata S, Salvatore M
* Comparison between a dual-head and a brain-dedicated SPECT system in the measurement of the loss of dopamine transporters with [123I]FP-CIT (331 views)
Eur J Nucl Med (ISSN: 1619-7070, 1619-7089, 0340-6997), 2008 Jul; 35(7): 1343-1349.
Impact Factor: 4.532
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Cigliano L, Maresca B, Salvatore A, Nino M, Monfrecola G, Ayala F, Carlucci A, Pugliese RC, Pedone C, Abrescia P
* Haptoglobin from psoriatic patients exhibits decreased activity in binding haemoglobin and inhibiting lecithin-cholesterol acyltransferase activity (355 views)
Journal Of The European Academy Of Dermatology And Venereology (ISSN: 1468-3083, 0926-9959), 2008 Apr; 22(4): 417-425.
Impact Factor: 2.276
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Tauchmanova L, Pivonello R, De Martino MC, Rusciano A, De Leo M, Ruosi C, Mainolfi C, Lombardi G, Salvatore M, Colao A
* Effects of sex steroids on bone in women with subclinical or overt endogenous hypercortisolism (348 views)
Eur J Endocrinol (ISSN: 0804-4643), 2007 Sep; 157(3): 359-366.
Impact Factor: 3.239
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Tauchmanovà L, Pivonello R, Di Somma C, Rossi R, De Martino MC, Camera L, Klain M, Salvatore M, Lombardi G, Colao A
* Bone demineralization and vertebral fractures in endogenous cortisol excess: Role of disease etiology and gonadal status (305 views)
J Clin Endocrinol Metab (ISSN: 0021-972x), 2006 May; 91(5): 1779-1784.
Impact Factor: 5.799
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Colao A, Di Somma C, Cuocolo A, Spinelli L, Acampa W, Spiezia S, Rota F, Savanelli MC, Lombardi G
* Does a gender-related effect of growth hormone (GH) replacement exist on cardiovascular risk factors, cardiac morphology, and performance and atherosclerosis? Results of a two-year open, prospective study in young adult men and women with severe GH deficiency (407 views)
J Clin Endocrinol Metab (ISSN: 0021-972x), 2005 Sep; 90(9): 5146-5155.
Impact Factor: 6.02
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Colao A, Di Somma C, Cuocolo A, Filippella M, Rota F, Acampa W, Savastano S, Salvatore M, Lombardi G
* The severity of growth hormone deficiency correlates with the severity of cardiac impairment in 100 adult patients with hypopituitarism: An observational, case-control study (276 views)
J Clin Endocrinol Metab (ISSN: 0021-972x), 2004 Dec; 89(12): 5998-6004.
Impact Factor: 5.778
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Giacco R, Clemente G, Luongo D, Lasorella G, Fiume I, Brouns F, Bornet F, Patti L, Cipriano P, Rivellese AA, Riccardi G
* Effects of short-chain fructo-oligosaccharides on glucose and lipid metabolism in mild hypercholesterolaemic individuals (392 views)
Clin Nutr (ISSN: 0261-5614, 0261-5614linking), 2004 Jun; 23(3): 331-340.
Impact Factor: 2.019
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Varrone A, Salvatore E, De Michele G, Barone P, Sansone V, Pellecchia MT, Castaldo I, Coppola G, Brunetti A, Salvatore M, Pappata S, Filla A
* Reduced Striatal [123I]FP-CIT Binding in SCA2 Patients without Parkinsonism (387 views)
Annals Of Neurology, 2004 Mar; 55(3): 426-430.
Impact Factor: 11.91
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Mainenti PP, D'Agostino L, Soscia E, Romano M, Salvatore M
* Hepatic and splenic amyloidosis: Dual-phase spiral CT findings (306 views)
Abdom Imaging (ISSN: 0942-8925, 1432-0509), 2003 Sep; 28(5): 688-690.
Impact Factor: 0.996
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Tauchmanova L, De Rosa G, Serio B, Fazioli F, Mainolfi C, Lombardi G, Colao A, Salvatore M, Rotoli B, Selleri C
* Avascular necrosis in long-term survivors after allogeneic or autologous stem cell transplantation: A single center experience and a review (265 views)
Cancer (ISSN: 0008-543x), 2003 May 15; 97(10): 2453-2461.
Impact Factor: 2.045
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Di Somma C, Pivonello R, Loche S, Faggiano A, Klain M, Salvatore M, Lombardi G, Colao A
* Effect of 2 years of cortisol normalization on the impaired bone mass and turnover in adolescent and adult patients with Cushing's disease: A prospective study (416 views)
Clin Endocrinol (ISSN: 0300-0664, 1365-2265, 1365-2265electronic), 2003 Mar; 58(3): 302-308.
Impact Factor: 2.767
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Le Provost JB, Bartres-faz D, Paillere-martinot ML, Artiges E, Pappata S, Recasens C, Perez-gomez M, Bernardo M, Baeza I, Bayle F, Martinot JL
* Paracingulate sulcus morphology in men with early-onset schizophrenia (233 views)
Br J Psychiatry (ISSN: 0007-1250), 2003 Mar; 182(MAR.): 228-232.
Impact Factor: 4.421
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Colao A, Marzullo P, Cuocolo A, Spinelli L, Pivonello R, Bonaduce D, Salvatore M, Lombardi G
* Reversal of acromegalic cardiomyopathy in young but not in middle-aged patients after 12 months of treatment with the depot long-acting somatostatin analogue octreotide (412 views)
Clin Endocrinol (ISSN: 0300-0664, 1365-2265, 1365-2265electronic), 2003 Feb; 58(2): 169-176.
Impact Factor: 2.767
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Petretta M, Vicario ML, Spinelli L, Ferro A, Cuocolo A, Condorelli M, Bonaduce D
* Combined effect of the force-frequency and length-tension mechanisms on left ventricular function in patients with dilated cardiomyopathy (293 views)
Eur J Heart Fail European Journal Of Heart Failure (ISSN: 1388-9842), 2002 Dec; 4(6): 727-735.
Impact Factor: 2.134
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Ciampi Q, Betocchi S, Lombardi R, Manganelli F, Storto G, Losi MA, Pezzella E, Finizio F, Cuocolo A, Chiariello M
* Hemodynamic determinants of exercise-induced abnormal blood pressure response in hypertrophic cardiomyopathy (279 views)
Journal Of The American College Of Cardiology (ISSN: 0735-1097), 2002 Jul 17; 40(2): 278-284.
Impact Factor: 6.278
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Manganelli F, Betocchi S, Ciampi Q, Storto G, Losi MA, Violante A, Briguori C, Tocchetti CG, Lombardi R, Cuocolo A, Chiariello M
* Myopia and IOP (311 views)
Ann Ottalmol Clin Ocul, 2002 Jun 15; 115(10): 1053-1058.
Impact Factor: 0
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Colao A, Cuocolo A, Di Somma C, Cerbone G, Della Morte A, Pivonello R, Nicolai E, Salvatore M, Lombardi G
Does the age of onset of growth hormone deficiency affect cardiac performance? A radionuclide angiography study (277 views)
Clin Endocrinol (ISSN: 0300-0664, 1365-2265, 1365-2265electronic), 2000 Apr; 52(4): 447-455.
Impact Factor: 2.922
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Pace L, Perrone-Filardi P, Mainenti PP, Cuocolo A, Vezzuto P, Prastaro M, Varrone A, De Luca G, Soricelli A, Betocchi S, Chiariello M, Salvatore M
Identification of viable myocardium in patients with chronic coronary artery disease using rest-redistribution thallium-201 tomography: Optimal image analysis (379 views)
J Nucl Med (ISSN: 0161-5505, 1535-5667, 1535-5667electronic), 1998 Nov; 39(11): 1869-1874.
Impact Factor: 3.064
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De Michele G, Mainenti PP, Soricelli A, Di Salle F, Salvatore E, Longobardi MR, Postiglione A, Salvatore M, Filla A
Cerebral blood flow in spinocerebellar degenerations: a single photon emission tomography study in 28 patients (252 views)
J Neurol (ISSN: 0340-5354, 1432-1459, 1432-1459electronic), 1998 Sep; 245(9): 603-608.
Impact Factor: 2.3
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Petretta M, Cuocolo A, Nicolai E, Acampa W, Salvatore M, Bonaduce D
Combined assessment of left ventricular function and rest-redistribution regional myocardial thallium-201 activity for prognostic evaluation of patients with chronic coronary artery disease and left ventricular dysfunction (349 views)
J Nucl Cardiol (ISSN: 1071-3581, 1532-6551, 1532-6551electronic), 1998 Jul; 5(4): 378-386.
Impact Factor: 1.336
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Fonti R, Latella G, Caprilli R, Frieri G, Marcheggiano A, Sambuy Y
Carbonic anhydrase I reduction in colonic mucosa of patients with active ulcerative colitis (400 views)
Digestive Diseases And Sciences (ISSN: 0163-2116), 1998; 43(9): 2086-2092.
Impact Factor: 1.972
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Cuocolo A, Nicolai E, Petretta M, Morisco C, DeLuca N, Salvatore M, Trimarco B
One-year effect of myocardial revascularization on resting left ventricular function and regional thallium uptake in chronic CAD (326 views)
J Nucl Med (ISSN: 0161-5505, 1535-5667, 1535-5667electronic), 1997 Nov; 38(11): 1684-1692.
Impact Factor: 3.491
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Nappi A, Cuocolo A, Imbriaco M, Nicolai E, Varrone A, Morisco C, Romano M, Trimarco B, Salvatore M
Ambulatory monitoring of left ventricular function: Walk and bicycle exercise in congestive heart failure (286 views)
J Nucl Med (ISSN: 0161-5505, 1535-5667, 1535-5667electronic), 1997 Jun; 38(6): 948-953.
Impact Factor: 3.491
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Soricelli A, Postiglione A, GrivetFojaja M, Mainenti PP, Discepolo A, Varrone A, Salvatore M, Lassen N
Reduced cortical distribution volume of iodine-123 iomazenil in Alzheimer's disease as a measure of loss of synapses (391 views)
Eur J Nucl Med (ISSN: 0340-6997, 1619-7070, 1619-7089), 1996 Oct; 23(10): 1323-1328.
Impact Factor: 2.692
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Nicolai E, Cuocolo A, Pace L, Maurea S, Nappi A, Imbriaco M, Morisco C, Argenziano L, Salvatore M
Assessment of systolic wall thickening using technetium-99m methoxyisobutylisonitrile in patients with coronary artery disease: relation to thallium-201 scintigraphy with re-injection (313 views)
Eur J Nucl Med (ISSN: 0340-6997, 1619-7070, 1619-7089), 1995 Sep; 22(9): 1017-1022.
Impact Factor: 2.692
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Ferrara LA, Mancini M, Iannuzzi R, Marotta T, Gaeta I, Pasanisi F, Postiglione A, Guida L
CAROTID DIAMETER AND BLOOD-FLOW VELOCITIES IN CEREBRAL-CIRCULATION IN HYPERTENSIVE PATIENTS (205 views)
Stroke (ISSN: 0039-2499), 1995 Mar; 26(3): 418-421.
Impact Factor: 4.323
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Testino G, Leone S, Fagoonee S, Del Bas JM, Rodriguez B, Puiggros F, Marine S, Rodriguez MA, Morina D, Armengol L, Caimari A, Arola L, Cimini FA, Barchetta I, Carotti S, Bertoccini L, Baroni MG, Vespasiani-gentilucci U, Cavallo MG, Morini S, Nelson JE, Roth CL, Wilson LA, Yates KP, Aouizerat B, Morgan-stevenson V, Whalen E, Hoofnagle A, Mason M, Gersuk V, Yeh MM, Kowdley KV, Lee SM, Jun DW, Cho YK, Jang KS, Kucukazman M, Ata N, Dal K, Yeniova AO, Kefeli A, Basyigit S, Aktas B, Akin KO, Agladioglu K, Ure OS, Topal F, Nazligul Y, Beyan E, Ertugrul DT, Catena C, Cosma C, Camozzi V, Plebani M, Ermani M, Sechi LA, Fallo F, Goto Y, Ray MB, Mendenhall CL, French SW, Gartside PS
Serum vitamin A deficiency and increased intrahepatic expression of cytokeratin antigen in alcoholic liver disease (582 views)
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Impact Factor: 0.913
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* Brain-gut-liver interactions across the spectrum of insulin resistance in metabolic fatty liver disease (31 views)
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Impact Factor: 3.665
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Testino G, Fagoonee S, Balbinot P, Pellicano R
* Alcohol-related liver disease in patients admitted to intensive care unit: how to define alcohol consumption? (8 views)
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Impact Factor: 2.329
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Vitale M, Giacco R, Laiola M, Della Pepa G, Luongo D, Mangione A, Salamone D, Vitaglione P, Ercolini D, Rivellese AA
* Acute and chronic improvement in postprandial glucose metabolism by a diet resembling the traditional Mediterranean dietary pattern: Can SCFAs play a role? (41 views)
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Impact Factor: 6.36
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Tosco A, Sepe A, Castaldo A, Catzola A, Cimbalo C, Angelini V, Vallone G, Buzzetti R, Raia V, Caprio MG
* Non-invasive tools for detection of liver disease in children and adolescents with cystic fibrosis (6 views) (PDF 7 views)
N/D, 2021; N/D: N/D-N/D.
Impact Factor: 2.488
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Balsano C, Alisi A, Brunetto MR, Invernizzi P, Burra P, Piscaglia F
The application of artificial intelligence in hepatology: A systematic review (1 views)
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Impact Factor:
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Abenavoli L, Scarpellini E, Pellicano R, Fagoonee S, Larussa T, Luzza F
* Mediterranean diet and probiotics supplementation to treat non-alcoholic fatty liver disease (28 views)
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Impact Factor: 3.031
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Testino G, Fagoonee S
* Coronavirus disease 2019 outbreak: liver disease a prognostic tool? (58 views)
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Impact Factor: 3.467
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Di Serafino M, Severino R, Gioioso M, Rossi E, Vezzali N, Pelliccia P, Caprio MG, Acampora C, Iorio R, Vallone G
* Paediatric liver ultrasound: a pictorial essay (150 views) (PDF 81 views)
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Impact Factor: 1.547
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Cernigliaro V, Peluso R, Zedda B, Silengo L, Tolosano E, Pellicano R, Altruda F, Fagoonee S
* Evolving Cell-Based and Cell-Free Clinical Strategies for Treating Severe Human Liver Diseases (116 views)
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Impact Factor: 4.366
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Negri R, Trinchese G, Carbone F, Caprio MG, Stanzione G, Di Scala C, Micillo T, Perna F, Tarotto L, Gelzo M, Cavaliere G, Spagnuolo MI, Corso G, Mattace Raso G, Matarese G, Mollica MP, Greco L, Iorio R
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Impact Factor: 5.688
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Gandhi S, Marr K, Mancini M, Caprio MG, Jakimovski D, Chandra A, Hagemeier J, Hojnacki D, Kolb C, Weinstock-guttman B, Zivadinov R
* No association between variations in extracranial venous anatomy and clinical outcomes in multiple sclerosis patients over 5 years (175 views)
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Impact Factor: 2.17
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Klisic A, Abenavoli L, Fagoonee S, Kavaric N, Kocic G, Ninic A
* Older age and HDL-cholesterol as independent predictors of liver fibrosis assessed by BARD score (156 views)
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Impact Factor: 2.863
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Durazzo M, Ponzo E, Bonetto S, Fagoonee S, Pellicano R
* Liver diseases in the elderly (344 views)
Hepatology (ISSN: 0026-4806linking, 1827-1669electronic), 2018 Oct 11; 110(1): 35-51.
Impact Factor: 2.863
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Testino G, Leone S, Fagoonee S, Pellicano R
* The role of adenosyl-methionine in alcoholic liver disease and intrahepatic cholestasis (120 views)
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Impact Factor: 1.29
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Mancini M, Summers P, Faita F, Brunetto MR, Callea F, De Nicola A, Di Lascio N, Farinati F, Gastaldelli A, Gridelli B, Mirabelli P, Neri E, Salvadori PA, Rebelos E, Tiribelli C, Valenti L, Salvatore M, Bonino F
* Digital liver biopsy: Bio-imaging of fatty liver for translational and clinical research (695 views) (PDF 135 views)
World J Hepatol (ISSN: 1948-5182print, 1948-5182electronic), 2018 Feb 27; 10(2): 231-245.
Impact Factor: 0.78
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Di Lascio N, Avigo C, Salvati A, Martini N, Ragucci M, Monti S, Prinster A, Chiappino D, Mancini M, D'Elia D, Ghiadoni L, Bonino F, Brunetto MR, Faita F
* Steato-Score: Non-Invasive Quantitative Assessment of Liver Fat by Ultrasound Imaging (350 views)
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Impact Factor: 2.494
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Ricco G, Cavallone D, Cosma C, Caviglia GP, Oliveri F, Biasiolo A, Abate ML, Plebani M, Smedile A, Bonino F, Pontisso P, Brunetto MR
* Impact of etiology of chronic liver disease on hepatocellular carcinoma biomarkers (484 views)
Cancer Biomark (ISSN: 1574-0153, 1574-0153linking), 2017 Dec 15; 21(3): 603-612.
Impact Factor: 2.392
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Mancini M, Salomone Megna A, Ragucci M, De Luca M, Marino Marsilia G, Nardone G, Coccoli P, Prinster A, Mannelli L, Vergara E, Monti S, Liuzzi R, Incoronato M
* Reproducibility of shear wave elastography (SWE) in patients with chronic liver disease (218 views)
Plosone (ISSN: 1932-6203, 1932-6203electronic, 1932-6203linking), 2017 Oct 12; 12(10): e0185391-e0185391.
Impact Factor: 2.766
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Caprio MG, Marr K, Gandhi S, Jakimovski D, Hagemeier J, Weinstock-guttman B, Zivadinov R, Mancini M
* Centralized and local color Doppler ultrasound reading agreement for diagnosis of the chronic cerebrospinal venous insufficiency in patients with Multiple Sclerosis (223 views)
Curr Neurovasc Res (ISSN: 1567-2026, 1567-2026linking), 2017 Jul 17; 14(3): 266-273.
Impact Factor: 1.716
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Fagoonee S, Famulari ES, Silengo L, Camussi G, Altruda F
* Prospects for Adult Stem Cells in the Treatment of Liver Diseases (198 views)
Stem Cells Dev (ISSN: 1547-3287, 1547-3287linking), 2016 Sep 7; 25(20): 1471-1482.
Impact Factor: 3.562
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Pisani A, Sabbatini M, Imbriaco M, Riccio E, Rubis N, Prinster A, Perna A, Liuzzi R, Spinelli L, Santangelo M, Remuzzi G, Ruggenenti P
* Long-term Effects of Octreotide on Liver Volume in Patients With Polycystic Kidney and Liver Disease (263 views)
Clin Gastroenterol H (ISSN: 1542-3565), 2016 Feb 1; N/D: N/D-N/D.
Impact Factor: 7.398
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Petta S, Valenti L, Bugianesi E, Targher G, Bellentani S, Bonino F, Fargion S, Vanni E, Ferrannini E, Loguercio C, Lonardo A, Marra F, Mancini M, Miele L, Nobili V, Baroni GS, Alessandro F, Ballestri S, Brunetto MR, Coco B, Grieco A, Kondili L, Nascimbeni F, Prinster A, Romagnoli D, Taddei S, Vella S
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Dig Liver Dis (ISSN: 1590-8658, 1590-8658linking), 2016; 48(3): 333-342.
Impact Factor: 3.061
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Ribaldone DG, Garavagno M, Pellicano R, Bresso F, Fagoonee S, David E, Sapone N, Bonagura AG, Resegotti A, Astegiano M
* Prevalence and prognostic value of hepatic histological alterations in patients with Crohn's disease (286 views)
Scand J Gastroentero (ISSN: 0036-5521, 0036-5521linking), 2015; 50(12): 1463-1468.
Impact Factor: 2.199
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Salvatore E, Tedeschi E, Mollica C, Vicidomini C, Varrone A, Coda ARD, Brunetti A, Salvatore M, De Michele G, Filla A, Pappata S
* Supratentorial and infratentorial damage in spinocerebellar ataxia 2: a diffusion-weighted MRI study (344 views)
Mov Disord (ISSN: 0885-3185, 1531-8257, 0885-3185linking), 2014 May; 29(6): 780-786.
Impact Factor: 5.68
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Mancini M, Lanzillo R, Liuzzi R, Di Donato O, Ragucci M, Monti S, Salvatore E, Morra VB, Salvatore M
* Internal jugular vein blood flow in multiple sclerosis patients and matched controls (347 views) (PDF 199 views)
Plosone (ISSN: 1932-6203, 1932-6203electronic, 1932-6203linking), 2014 Mar 27; 9(3): e92730-e92730.
Impact Factor: 3.234
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Storto G, Gallicchio R, Maddalena F, Pellegrino T, Petretta M, Fiumara G, Cuocolo A
* Estimation of coronary flow reserve by sestamibi imaging in patients with mild hypertension and normal coronary arteries (307 views)
Q J Nucl Med Mol Im (ISSN: 1824-4785, 1824-4478, 1827-1936), 2014 Mar 14; 59(3): 336-341.
Impact Factor: 2.033
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Molino I, Cavaliere C, Salvatore E, Quarantelli M, Colucci L, Fasanaro AM
* Is anterior communicating artery syndrome related to fornix lesions? (266 views)
J Alzheimers Dis (ISSN: 1387-2877, 1387-2877linking), 2014; 42Suppl3: S199-S199.
Impact Factor: 4.151
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Comi G, Battaglia MA, Bertolotto A, Del Sette M, Ghezzi A, Malferrari G, Salvetti M, Sormani MP, Tesio L, Stolz E, Zaratin P, Mancardi G, Mancini M
* Observational case-control study of the prevalence of chronic cerebrospinal venous insufficiency in multiple sclerosis: results from the CoSMo study (255 views)
Mult Scler (ISSN: 1477-0970, 1352-4585, 1352-4585linking), 2013 Oct; 19(11): 1508-1517.
Impact Factor: 4.863
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Vitale M, Luongo D, Naviglio D, Bozzetto L, Mirabella M, Rivieccio AM, Giacco A, Rivellese AA
* Trans fatty acids consumption in type 1 diabetic patients: evaluation by dietary records and measurement in serum phospholipids (365 views)
Acta Diabetol (ISSN: 0940-5429, 1432-5233electronic), 2013 Aug; 50(4): 651-654.
Impact Factor: 3.679
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Pasanisi F, Pace L, Fonti R, Marra M, Sgambati D, De Caprio C, De Filippo E, Vaccaro A, Salvatore M, Contaldo F
* Evidence of brown fat activity in constitutional leanness (480 views)
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Impact Factor: 6.31
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Lanzillo R, Mancini M, Liuzzi R, Di Donato O, Salvatore E, Maglio V, Vacca G, Amato L, D'Anna G, Brunetti A, Brescia Morra V
* Chronic cerebrospinal venous insufficiency in multiple sclerosis: a highly prevalent age-dependent phenomenon (455 views)
Bmc Neurol (ISSN: 1471-2377, 1471-2377linking), 2013 Feb 13; 13: 20-20.
Impact Factor: 2.486
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Erro R, Pappata S, Amboni M, Vicidomini C, Longo K, Santangelo G, Picillo M, Vitale C, Moccia M, Giordano F, Brunetti A, Pellecchia MT, Salvatore M, Barone P
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Impact Factor: 3.274
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Marciano C, Galderisi M, Gargiulo P, Acampa W, D'Amore C, Esposito R, Capasso E, Savarese G, Casaretti L, Lo Iudice F, Esposito G, Rengo G, Leosco D, Cuocolo A, Perrone-Filardi P
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Impact Factor: 5.114
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Pier PM
* RE: Imaging Features of Hepato-Splenic Amyloidosis at PET/CT (283 views)
Korean Journal Of Radiology (ISSN: 1229-6929), 2012 May; 13(3): 368-369.
Impact Factor: 1.555
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Mancini M, Morra VB, Di Donato O, Maglio V, Lanzillo R, Liuzzi R, Salvatore E, Brunetti A, Iaccarino V, Salvatore M
* Multiple sclerosis: cerebral circulation time (384 views)
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Impact Factor: 6.339
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Lanzillo R, Di Somma C, Quarantelli M, Ventrella G, Gasperi M, Prinster A, Vacca G, Pivonello C, Orefice G, Colao A, Morra VB
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Impact Factor: 3.692
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Giacco R, Della Pepa G, Luongo D, Riccardi G
* Whole grain intake in relation to body weight: From epidemiological evidence to clinical trials (536 views)
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Impact Factor: 3.731
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Pappata S, Santangelo G, Aarsland D, Vicidomini C, Longo K, Bronnick K, Amboni M, Erro R, Vitale C, Caprio MG, Pellecchia MT, Brunetti A, De Michele G, Salvatore M, Barone P
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Impact Factor: 8.312
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Dinacci D, Tessitore A, Russo AA, De Bonis ML, Lavorgna L, Picconi O, Sacco R, Bonavita S, Gallo A, Servillo G, Marcuccio L, Comerci M, Galletti P, Alfano B, Tedeschi G
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Impact Factor: 1.315
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Pappata S, Varrone A, Vicidomini C, Milan G, De Falco C, Sansone V, Iavarone A, Comerci M, Loré E, Panico M, Quarantelli M, Postiglione A, Salvatore M
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Impact Factor: 5.036
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Galasso G, De Rosa R, Piscione F, Iaccarino G, Vosa C, Sorriento D, Piccolo R, Rapacciuolo A, Walsh K, Chiariello M
* Myocardial expression of FOXO3a-Atrogin-1 pathway in human heart failure (245 views)
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Impact Factor: 4.512
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Coppola G, Fortunato D, Auricchio G, Mainolfi C, Operto FF, Signoriello G, Pascotto A, Salvatore M
* Bone mineral density in children, adolescents, and young adults with epilepsy (348 views)
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Impact Factor: 4.052
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Lanzillo R, Di Somma C, Quarantelli M, Gasperi M, Ventrella G, Prinster A, Vacca G, Orefice G, Colao A, Morra VB
* Serum levels of insulin like growth factor-1 and insulin like growth factor binding protein-3 in relapsing and secondary progressive multiple sclerosis (328 views)
Mult Scler (ISSN: 1352-4585, 1477-0970, 1352-4585linking), 2009 Sep; 15(9): 1402-1406.
Impact Factor: 3.279
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Masulli M, Mancini M, Liuzzi R, Daniele S, Mainenti PP, Vergara E, Genovese S, Salvatore M, Vaccaro O
* Measurement of the intrarenal arterial resistance index for the identification and prediction of diabetic nephropathy (561 views)
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Impact Factor: 3.517
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Gentile I, Viola C, Graf M, Liuzzi R, Quarto M, Cerini R, Piazza M, Borgia G
* A simple noninvasive score predicts gastroesophageal varices in patients with chronic viral hepatitis (369 views)
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Impact Factor: 2.207
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Spinelli L, Nicolai E, Acampa W, Imbriaco M, Pisani A, Rao MA, Scopacasa F, Cianciaruso B, De Luca N, Cuocolo A
* Cardiac performance during exercise in patients with Fabry's disease (348 views)
Eur J Clin Invest (ISSN: 0014-2972, 1365-2362, 0014-2972linking), 2008 Dec; 38(12): 910-917.
Impact Factor: 2.784
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De Bonis S, Rendina D, Vargas G, Minno DD, Piedimonte V, Gallotta G, Postiglione A
* Predictors of In-Hospital and Long-Term Clinical Outcome in Elderly Patients with Massive Pulmonary Embolism Receiving Thrombolytic Therapy (316 views)
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Impact Factor: 3.805
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Varrone A, Sansone V, Pellecchia MT, Amboni M, Salvatore E, De Michele G, Filla A, Barone P, Pappata S, Salvatore M
* Comparison between a dual-head and a brain-dedicated SPECT system in the measurement of the loss of dopamine transporters with [123I]FP-CIT (331 views)
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Impact Factor: 4.532
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Cigliano L, Maresca B, Salvatore A, Nino M, Monfrecola G, Ayala F, Carlucci A, Pugliese RC, Pedone C, Abrescia P
* Haptoglobin from psoriatic patients exhibits decreased activity in binding haemoglobin and inhibiting lecithin-cholesterol acyltransferase activity (355 views)
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Impact Factor: 2.276
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Tauchmanova L, Pivonello R, De Martino MC, Rusciano A, De Leo M, Ruosi C, Mainolfi C, Lombardi G, Salvatore M, Colao A
* Effects of sex steroids on bone in women with subclinical or overt endogenous hypercortisolism (348 views)
Eur J Endocrinol (ISSN: 0804-4643), 2007 Sep; 157(3): 359-366.
Impact Factor: 3.239
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Tauchmanovà L, Pivonello R, Di Somma C, Rossi R, De Martino MC, Camera L, Klain M, Salvatore M, Lombardi G, Colao A
* Bone demineralization and vertebral fractures in endogenous cortisol excess: Role of disease etiology and gonadal status (305 views)
J Clin Endocrinol Metab (ISSN: 0021-972x), 2006 May; 91(5): 1779-1784.
Impact Factor: 5.799
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Colao A, Di Somma C, Cuocolo A, Spinelli L, Acampa W, Spiezia S, Rota F, Savanelli MC, Lombardi G
* Does a gender-related effect of growth hormone (GH) replacement exist on cardiovascular risk factors, cardiac morphology, and performance and atherosclerosis? Results of a two-year open, prospective study in young adult men and women with severe GH deficiency (407 views)
J Clin Endocrinol Metab (ISSN: 0021-972x), 2005 Sep; 90(9): 5146-5155.
Impact Factor: 6.02
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Colao A, Di Somma C, Cuocolo A, Filippella M, Rota F, Acampa W, Savastano S, Salvatore M, Lombardi G
* The severity of growth hormone deficiency correlates with the severity of cardiac impairment in 100 adult patients with hypopituitarism: An observational, case-control study (276 views)
J Clin Endocrinol Metab (ISSN: 0021-972x), 2004 Dec; 89(12): 5998-6004.
Impact Factor: 5.778
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Giacco R, Clemente G, Luongo D, Lasorella G, Fiume I, Brouns F, Bornet F, Patti L, Cipriano P, Rivellese AA, Riccardi G
* Effects of short-chain fructo-oligosaccharides on glucose and lipid metabolism in mild hypercholesterolaemic individuals (392 views)
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Impact Factor: 2.019
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Varrone A, Salvatore E, De Michele G, Barone P, Sansone V, Pellecchia MT, Castaldo I, Coppola G, Brunetti A, Salvatore M, Pappata S, Filla A
* Reduced Striatal [123I]FP-CIT Binding in SCA2 Patients without Parkinsonism (387 views)
Annals Of Neurology, 2004 Mar; 55(3): 426-430.
Impact Factor: 11.91
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Mainenti PP, D'Agostino L, Soscia E, Romano M, Salvatore M
* Hepatic and splenic amyloidosis: Dual-phase spiral CT findings (306 views)
Abdom Imaging (ISSN: 0942-8925, 1432-0509), 2003 Sep; 28(5): 688-690.
Impact Factor: 0.996
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Tauchmanova L, De Rosa G, Serio B, Fazioli F, Mainolfi C, Lombardi G, Colao A, Salvatore M, Rotoli B, Selleri C
* Avascular necrosis in long-term survivors after allogeneic or autologous stem cell transplantation: A single center experience and a review (265 views)
Cancer (ISSN: 0008-543x), 2003 May 15; 97(10): 2453-2461.
Impact Factor: 2.045
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Di Somma C, Pivonello R, Loche S, Faggiano A, Klain M, Salvatore M, Lombardi G, Colao A
* Effect of 2 years of cortisol normalization on the impaired bone mass and turnover in adolescent and adult patients with Cushing's disease: A prospective study (416 views)
Clin Endocrinol (ISSN: 0300-0664, 1365-2265, 1365-2265electronic), 2003 Mar; 58(3): 302-308.
Impact Factor: 2.767
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Le Provost JB, Bartres-faz D, Paillere-martinot ML, Artiges E, Pappata S, Recasens C, Perez-gomez M, Bernardo M, Baeza I, Bayle F, Martinot JL
* Paracingulate sulcus morphology in men with early-onset schizophrenia (233 views)
Br J Psychiatry (ISSN: 0007-1250), 2003 Mar; 182(MAR.): 228-232.
Impact Factor: 4.421
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Colao A, Marzullo P, Cuocolo A, Spinelli L, Pivonello R, Bonaduce D, Salvatore M, Lombardi G
* Reversal of acromegalic cardiomyopathy in young but not in middle-aged patients after 12 months of treatment with the depot long-acting somatostatin analogue octreotide (412 views)
Clin Endocrinol (ISSN: 0300-0664, 1365-2265, 1365-2265electronic), 2003 Feb; 58(2): 169-176.
Impact Factor: 2.767
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Petretta M, Vicario ML, Spinelli L, Ferro A, Cuocolo A, Condorelli M, Bonaduce D
* Combined effect of the force-frequency and length-tension mechanisms on left ventricular function in patients with dilated cardiomyopathy (293 views)
Eur J Heart Fail European Journal Of Heart Failure (ISSN: 1388-9842), 2002 Dec; 4(6): 727-735.
Impact Factor: 2.134
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Ciampi Q, Betocchi S, Lombardi R, Manganelli F, Storto G, Losi MA, Pezzella E, Finizio F, Cuocolo A, Chiariello M
* Hemodynamic determinants of exercise-induced abnormal blood pressure response in hypertrophic cardiomyopathy (279 views)
Journal Of The American College Of Cardiology (ISSN: 0735-1097), 2002 Jul 17; 40(2): 278-284.
Impact Factor: 6.278
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Manganelli F, Betocchi S, Ciampi Q, Storto G, Losi MA, Violante A, Briguori C, Tocchetti CG, Lombardi R, Cuocolo A, Chiariello M
* Myopia and IOP (311 views)
Ann Ottalmol Clin Ocul, 2002 Jun 15; 115(10): 1053-1058.
Impact Factor: 0
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Colao A, Cuocolo A, Di Somma C, Cerbone G, Della Morte A, Pivonello R, Nicolai E, Salvatore M, Lombardi G
Does the age of onset of growth hormone deficiency affect cardiac performance? A radionuclide angiography study (277 views)
Clin Endocrinol (ISSN: 0300-0664, 1365-2265, 1365-2265electronic), 2000 Apr; 52(4): 447-455.
Impact Factor: 2.922
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Pace L, Perrone-Filardi P, Mainenti PP, Cuocolo A, Vezzuto P, Prastaro M, Varrone A, De Luca G, Soricelli A, Betocchi S, Chiariello M, Salvatore M
Identification of viable myocardium in patients with chronic coronary artery disease using rest-redistribution thallium-201 tomography: Optimal image analysis (379 views)
J Nucl Med (ISSN: 0161-5505, 1535-5667, 1535-5667electronic), 1998 Nov; 39(11): 1869-1874.
Impact Factor: 3.064
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De Michele G, Mainenti PP, Soricelli A, Di Salle F, Salvatore E, Longobardi MR, Postiglione A, Salvatore M, Filla A
Cerebral blood flow in spinocerebellar degenerations: a single photon emission tomography study in 28 patients (252 views)
J Neurol (ISSN: 0340-5354, 1432-1459, 1432-1459electronic), 1998 Sep; 245(9): 603-608.
Impact Factor: 2.3
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Petretta M, Cuocolo A, Nicolai E, Acampa W, Salvatore M, Bonaduce D
Combined assessment of left ventricular function and rest-redistribution regional myocardial thallium-201 activity for prognostic evaluation of patients with chronic coronary artery disease and left ventricular dysfunction (349 views)
J Nucl Cardiol (ISSN: 1071-3581, 1532-6551, 1532-6551electronic), 1998 Jul; 5(4): 378-386.
Impact Factor: 1.336
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Fonti R, Latella G, Caprilli R, Frieri G, Marcheggiano A, Sambuy Y
Carbonic anhydrase I reduction in colonic mucosa of patients with active ulcerative colitis (400 views)
Digestive Diseases And Sciences (ISSN: 0163-2116), 1998; 43(9): 2086-2092.
Impact Factor: 1.972
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Cuocolo A, Nicolai E, Petretta M, Morisco C, DeLuca N, Salvatore M, Trimarco B
One-year effect of myocardial revascularization on resting left ventricular function and regional thallium uptake in chronic CAD (326 views)
J Nucl Med (ISSN: 0161-5505, 1535-5667, 1535-5667electronic), 1997 Nov; 38(11): 1684-1692.
Impact Factor: 3.491
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Nappi A, Cuocolo A, Imbriaco M, Nicolai E, Varrone A, Morisco C, Romano M, Trimarco B, Salvatore M
Ambulatory monitoring of left ventricular function: Walk and bicycle exercise in congestive heart failure (286 views)
J Nucl Med (ISSN: 0161-5505, 1535-5667, 1535-5667electronic), 1997 Jun; 38(6): 948-953.
Impact Factor: 3.491
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Soricelli A, Postiglione A, GrivetFojaja M, Mainenti PP, Discepolo A, Varrone A, Salvatore M, Lassen N
Reduced cortical distribution volume of iodine-123 iomazenil in Alzheimer's disease as a measure of loss of synapses (391 views)
Eur J Nucl Med (ISSN: 0340-6997, 1619-7070, 1619-7089), 1996 Oct; 23(10): 1323-1328.
Impact Factor: 2.692
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Nicolai E, Cuocolo A, Pace L, Maurea S, Nappi A, Imbriaco M, Morisco C, Argenziano L, Salvatore M
Assessment of systolic wall thickening using technetium-99m methoxyisobutylisonitrile in patients with coronary artery disease: relation to thallium-201 scintigraphy with re-injection (313 views)
Eur J Nucl Med (ISSN: 0340-6997, 1619-7070, 1619-7089), 1995 Sep; 22(9): 1017-1022.
Impact Factor: 2.692
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Ferrara LA, Mancini M, Iannuzzi R, Marotta T, Gaeta I, Pasanisi F, Postiglione A, Guida L
CAROTID DIAMETER AND BLOOD-FLOW VELOCITIES IN CEREBRAL-CIRCULATION IN HYPERTENSIVE PATIENTS (205 views)
Stroke (ISSN: 0039-2499), 1995 Mar; 26(3): 418-421.
Impact Factor: 4.323
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Testino G, Leone S, Fagoonee S, Del Bas JM, Rodriguez B, Puiggros F, Marine S, Rodriguez MA, Morina D, Armengol L, Caimari A, Arola L, Cimini FA, Barchetta I, Carotti S, Bertoccini L, Baroni MG, Vespasiani-gentilucci U, Cavallo MG, Morini S, Nelson JE, Roth CL, Wilson LA, Yates KP, Aouizerat B, Morgan-stevenson V, Whalen E, Hoofnagle A, Mason M, Gersuk V, Yeh MM, Kowdley KV, Lee SM, Jun DW, Cho YK, Jang KS, Kucukazman M, Ata N, Dal K, Yeniova AO, Kefeli A, Basyigit S, Aktas B, Akin KO, Agladioglu K, Ure OS, Topal F, Nazligul Y, Beyan E, Ertugrul DT, Catena C, Cosma C, Camozzi V, Plebani M, Ermani M, Sechi LA, Fallo F, Goto Y, Ray MB, Mendenhall CL, French SW, Gartside PS
Serum vitamin A deficiency and increased intrahepatic expression of cytokeratin antigen in alcoholic liver disease (582 views)
Hepatology (ISSN: 1827-1669electronic, 0026-4806linking), 1988 Sep; 83120693611123109(5): 1019-1026.
Impact Factor: 0.913
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74 Records (72 excluding Abstracts).
Total impact factor: 255.632 (249.448 excluding Abstracts).
Total 5 year impact factor: 257.392 (251.012 excluding Abstracts).
Total impact factor: 255.632 (249.448 excluding Abstracts).
Total 5 year impact factor: 257.392 (251.012 excluding Abstracts).
386 views. Last view on Thursday 08 September 2022, 11:03:34
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