Keywords: Dna, Gamma Sulfate Peptide Nucleic Acid, Monomer, Oligomer, Unclassified Drug, Dna Binding Protein, Epidermal Growth Factor Receptor 2, Erbb2 Protein, Human, Article, Binding Affinity, Cell Line, Controlled Study, Erbb2 Gene, Fluorescence Activated Cell Sorting, Gene Expression, Gene Overexpression, Genetic Transcription, Human Cell, Inhibition Kinetics, Nuclear Magnetic Resonance Spectroscopy, Nucleic Acid Structure, Polymerase Chain Reaction, Protein Conformation, Protein Secondary Structure, Protein Stability, Quantitative Analysis, Chemistry, Metabolism, Molecular Mimicry, Solubility, Synthesis, Dna-Binding Proteins, Protein Structure, Chemical Synthesis,
Affiliations: *** IBB - CNR ***
Dipartimento delle Scienze Biologiche, Facoltà di Scienze Biotecnologiche, Università di Napoli Federico II, Napoli, Italy
Dipartimento di Scienze Ambientali, Seconda Università degli Studi di Napoli, Caserta, Italy
Istituto di Biostrutture e Bioimmagini (CNR), Napoli, Italy
Istituto di Cristallografia (CNR), Bari, Italy
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Xu, J. C., Wu, Y., Synthesis of chiral peptide nucleic acids using Fmoc chemistry (2001) Tetrahedron, 57, pp. 8107-8113
de Koning, M. C., Petersen, L., Weterings, J. J., Overhand, M., van der Marel, G. A., Synthesis of thiol-modified peptide nucleic acids designed for post-assembly conjugation reactions (2006) Tetrahedron, 62, pp. 3248-3258
Englund, E. A., Appella, D. H., Gamma-substituted peptide nucleic acids constructed from L-lysine are a versatile scaffold for multifunctional display (2007) Angewandte Chemie, 46, pp. 1414-1418
Seo, Y. J., Lim, J., Lee, E. H., Ok, T., Yoon, J., Base pair opening kinetics study of the aegPNA: DNA hydrid duplex containing a site-specific GNA-like chiral PNA monomer (2011) Nucleic Acids Research, 39, pp. 7329-7335
Yeh, J. I., Shivachev, B., Rapireddy, S., Crawford, M. J., Gil, R. R., Crystal structure of chiral gammaPNA with complementary DNA strand: insights into the stability and specificity of recognition and conformational preorganization (2010) Journal of the American Chemical Society, 132, pp. 10717-10727
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Doyle, D. F., Braasch, D. A., Simmons, C. G., Janowski, B. A., Corey, D. R., Inhibition of gene expression inside cells by peptide nucleic acids: effect of mRNA target sequence, mismatched bases, and PNA length (2001) Biochemistry, 40, pp. 53-64
Zhilina, Z. V., Ziemba, A. J., Nielsen, P. E., Ebbinghaus, S. W., PNA-nitrogen mustard conjugates are effective suppressors of HER-2/neu and biological tools for recognition of PNA/DNA interactions (2006) Bioconjugate Chemistry, 17, pp. 214-222
Finn, P. J., Gibson, N. J., Fallon, R., Hamilton, A., Brown, T., Synthesis and properties of DNA-PNA chimeric oligomers (1996) Nucleic Acids Research, 24, pp. 3357-3363
Mokhir, A. A., Kraemer, R., Conjugates of PNA with naphthalene diimide derivatives having a broad range of DNA affinities (2003) Bioconjugate Chemistry, 14, pp. 877-883
Ross, G. F., Smith, P. M., McGregor, A., Turnbull, D. M., Lightowlers, R. N., Synthesis of trifunctional PNA-benzophenone derivatives for mitochondrial targeting, selective DNA binding, and photo-cross-linking (2003) Bioconjugate Chemistry, 14, pp. 962-966
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Petraglia F, Singh AA, Carafa V, Nebbioso A, Conte M, Scisciola L, Valente S, Baldi A, Mandoli A, Petrizzi VB, Ingenito C, De Falco S, Cicatiello V, Apicella I, Janssen-megens EM, Kim B, Yi G, Logie C, Heath S, Ruvo M, Wierenga ATJ, Flicek P, Yaspo ML, Della Valle V, Bernard O, Tomassi S, Novellino E, Feoli A, Sbardella G, Gut I, Vellenga E, Stunnenberg HG, Mai A, Martens JHA, Altucci L * Combined HAT/EZH2 modulation leads to cancer-selective cell death(284 views) Oncotarget (ISSN: 1949-2553electronic, 1949-2553linking), 2018 May 22; 9(39): 25630-25646. Impact Factor:5.008 ViewExport to BibTeXExport to EndNote