Synthesis of novel MMT/acyl-protected nucleo alanine monomers for the preparation of DNA/alanyl-PNA chimeras (804 views)
Amino Acids (ISSN: 1438-2199, 0939-4451, 1438-2199electronic), 2010 May; 38(5): 1301-1309.
Export to BibTeX Export to EndNote
Paper type: Erratum, Research Support, Non-U. S. Gov'T, Priority Journal Article,
Impact factor: 4.106, 5-year impact factor: 3.541
Url: http://www.scopus.com/inward/record.url?eid=2-s2.0-77955860234&partnerID=40&md5=7729b91d30fef82f1c0613384bae417b
Keywords: Amino Acids, Dna Recognition, Molecular Beacon, Protecting Groups, Alpha Amino Acid, Monomer, N Alpha (4 Methoxyphenyldiphenylmethyl) Beta [n2 (isobutyryl)guanin 9 Yl]alanine, N Alpha (4 Monomethoxytrityl) Beta [n4 (4 Tert Butylbenzoyl)cytosin 1 Yl]alanine, N Alpha (4 Monomethoxytrityl) Beta [n6 (anisoyl)adenin 9 Yl]alanine, N Alpha (4 Monomethoxytrityl) Beta [thymin 1 Yl]alanine, N Alpha Tert Butoxycarbonyl Beta [n2 (isobutyryl)guanin 9 Yl]alanine, N Alpha Tert Butoxycarbonyl Beta [n4 (4 Tert Butylbenzoyl)cytosin 1 Yl]alanine, N Alpha Tert Butoxycarbonyl Beta [n6 (anisoyl)adenin 9 Yl]alanine, Nucleic Acid Base, Peptide Nucleic Acid, Phosphoramidous Acid, Unclassified Drug, Amino Acid Synthesis, Article, Controlled Study, Diastereoisomer, Dna Alkylation, Dna Synthesis, Enantioselectivity, Molecular Recognition, Polymerization, Precipitation, Priority Journal, Racemization, Solid Phase Synthesis, Stoichiometry, Acylation, Chemistry, Electrospray Mass Spectrometry, Infrared Spectrophotometry, Nuclear Magnetic Resonance Spectroscopy, Stereoisomerism, Electrospray Ionization, Erratum, N Alpha (4 Methoxyphenyldiphenylmethyl) Beta [n2 (isobutyryl) Guanin 9 Yl] Alanine, N Alpha (4 Monomethoxytrityl) Beta [n4 (4 Tert Butylbenzoyl) Cytosin 1 Yl] Alanine, N Alpha (4 Monomethoxytrityl) Beta [n6 (anisoyl) Adenin 9 Yl] Alanine, N Alpha (4 Monomethoxytrityl) Beta [thymin 1 Yl] Alanine, N Alpha Tert Butoxycarbonyl Beta [n2 (isobutyryl) Guanin 9 Yl] Alanine, N Alpha Tert Butoxycarbonyl Beta [n4 (4 Tert Butylbenzoyl) Cytosin 1 Yl] Alanine, N Alpha Tert Butoxycarbonyl Beta [n6 (anisoyl) Adenin 9 Yl] Alanine,
Affiliations:
*** IBB - CNR ***
Institut fur Organische und Biomolekulare Chemie, Georg-August-Universitat Gottingen, Tammannstr. 2, 37077, Gottingen, Germany.
Institut Für Organische und Biomolekulare Chemie, Georg-August-Universität Göttingen, Tammannstr. 2, 37077 Göttingen, Germany
Istituto di Biostrutture e Bioimmagini-CNR, Via Mezzocannone 16, 80134 Naples, Italy
Institut F r Organische und Biomolekulare Chemie, Georg-August-Universit t G ttingen, Tammannstr. 2, 37077 G ttingen, Germany
References:
Antopolsky, M., Azhayev, A., Stepwise solid-phase synthesis of peptide-oligonucleotide conjugates on new solid supports (1999) Helvetica Chimica Acta, 82 (12), pp. 2130-2140. , DOI 10.1002/(SICI)1522-2675(19991215)82:12<2130::AID-HLCA2130> 3.0. CO
Arar, K., Aubertin, A.M., Roche, A.C., Monsigny, M., Mayer, R., Synthesis and antiviral activity of peptide-oligonucleotide conjugates prepared by using N-a-(bromoacetyl)peptides (1995) Bioconjug Chem, 6, pp. 573-577
Arnold, L.D., Kalantar, T.H., Vederas, J.C., Conversion of serine to stereochemically pure β-substituted α-amino acids via β-lactones (1985) Journal of the American Chemical Society, 107 (24), pp. 7105-7109. , DOI 10.1021/ja00310a058
Bergmann, F., Bannwarth, W., Solid phase synthesis of directly linked peptide-oligodeoxynucleotide hybrids using standard synthesis protocols (1995) Tetrahedron Lett, 36, pp. 1839-1842
Breipohl, G., Will, D.W., Peyman, A., Uhlmann, E., Novel synthetic routes to PNA monomers and PNA-DNA linker molecules (1997) Tetrahedron, 53 (43), pp. 14671-14686. , DOI 10.1016/S0040-4020(97)01044-2, PII S0040402097010442
Canle, M.L., Clegg, W., Demirtas, I., Elsegood, M.R.J., Maskill, H., Preparations, X-ray crystal structure determinations, and base strength measurements of substituted tritylamines (2000) Journal of the Chemical Society. Perkin Transactions 2, (1), pp. 85-92
Didenko, V.V., (2002) Situ Detection of DNA Damage: Methods and Protocols, , Humana Press, Totowa
Diederichsen, U., Pairing properties of alanyl peptide nucleic acids containing an amino acid backbone with alternating configuration (1996) Angew Chem Int Ed Engl, 35, pp. 445-448
Diederichsen, U., Alanyl-PNA: Evidence for linear band structures based on guanine-cytosine base pairs (1997) Angew Chem Int Ed Engl, 36, pp. 1886-1889
Diederichsen, U., Weicherding, D., Interactions of amino acid side chains with nucleobases in alanyl-PNA (1999) Synlett, (SPEC. ISSUE), pp. 917-920
Ede, N.J., Tregear, G.W., Haralambidis, J., Routine preparation of thiol oligonucleotides: Application to the synthesis of oligonucleotide- peptide hybrids (1994) Bioconjug Chem, 5, pp. 373-378
Ficht, S., Mattes, A., Seitz, O., Single-nucleotide-specific PNA-peptide ligation on synthetic and PCR DNA templates (2004) Journal of the American Chemical Society, 126 (32), pp. 9970-9981. , DOI 10.1021/ja048845o
Forget, D., Boturyn, D., Defrancq, E., Lhomme, J., Dumy, P., Highly efficient synthesis of peptide-oligonucleotide conjugates: Chemoselective oxime and thiazolidine formation (2001) Chemistry - A European Journal, 7 (18), pp. 3976-3984. , DOI 10.1002/1521-3765(20010917)7:18<3976::AID-CHEM3976> 3.0.CO
Harrison, J.G., Balasubramanian, S., Synthesis and hybridization analysis of a small library of peptide-oligonucleotide conjugates (1998) Nucleic Acids Research, 26 (13), pp. 3136-3145. , DOI 10.1093/nar/26.13.3136
Howarth, N.M., Wakelin, L.P.G., α-PNA: A Novel Peptide Nucleic Acid Analogue of DNA (1997) Journal of Organic Chemistry, 62 (16), pp. 5441-5450
Knemeyer, J.-P., Marme, N., Sauer, M., Probes for detection of specific DNA sequences at the single-molecule level (2000) Analytical Chemistry, 72 (16), pp. 3717-3724. , DOI 10.1021/ac000024o
Kostrikis, L.G., Tyagi, S., Mhlanga, M.M., Ho, D.D., Kramer, F.R., Spectral genotyping of human alleles (1998) Science, 279 (5354), pp. 1228-1229. , DOI 10.1126/science.279.5354.1228
Timar, Z., Kovacs, L., Kovacs, G., Schmel, Z., Fmoc/Acyl protecting groups in the synthesis of polyamide (peptide) nucleic acid monomers (2000) Journal of the Chemical Society, Perkin Transactions 1, (1), pp. 19-26
Kranaster, R., Ketzer, P., Marx, A., Mutant DNA polymerase for improved detection of single-nucleotide variations in microarrayed primer extension (2008) Chembiochem, 9, pp. 694-697
Küsel, A., Zhang, J., Alvarino Gil, M., Stückl, C.A., Meyer-Klaucke, W., Meyer, F., Diederichsen, U., Metal binding within a peptidebased nucleobase stack with tuneable double strand topology (2005) Eur J Inorg Chem, 431, pp. 7-4324
Li, J.J., Fang, X., Schuster, S.M., Tan, W., Molecular beacons: A novel approach to detect protein - DNA interactions (2000) Angewandte Chemie - International Edition, 39 (6), pp. 1049-1052. , DOI 10.1002/(SICI)1521-3773(20000317)39:6<1049::AID-ANIE1049> 3.0. CO
Lohse, P., Oberhauser, B., Oberhauser-Hofbauer, B., Baschang, G., Eschenmoser, A., Chemie von α-Aminonitrilen. XVII. Oligo(nukleodipeptamidinium)- Salze (1996) Croatica Chemica Acta, 69 (2), pp. 535-562
Mamos, P., Sanida, C., Barlos, K., Preparation of N-tritylamino acids from N-trimethylsilylamino acid trimethylsilyl esters (1988) Liebigs Ann Chem, pp. 1083-1084
Matsuo, T., In situ visualization of messenger RNA for basic fibroblast growth factor in living cells (1998) Biochimica et Biophysica Acta - General Subjects, 1379 (2), pp. 178-184. , DOI 10.1016/S0304-4165(97)00090-1, PII S0304416597000901
McMinn, D.L., Greenberg, M.M., Convergent solution-phase synthesis of a nucleopeptide using a protected oligonucleotide (1999) Bioorganic and Medicinal Chemistry Letters, 9 (4), pp. 547-550. , DOI 10.1016/S0960-894X(99)00051-7, PII S0960894X99000517
Musumeci, D., Roviello, G.N., Valente, M., Sapio, R., Pedone, C., Bucci, E.M., New synthesis of PNA-30DNA linker monomers, useful building blocks to obtain PNA/DNA chimeras (2004) Biopolymers - Peptide Science Section, 76 (6), pp. 535-542. , DOI 10.1002/bip.20135
Ollivier, N., Olivier, C., Gouyette, C., Huynh-Dinh, T., Gras-Masse, H., Melnyk, O., Synthesis of oligonucleotide-peptide conjugates using hydrazone chemical ligation (2002) Tetrahedron Letters, 43 (6), pp. 997-999. , DOI 10.1016/S0040-4039(01)02315-2, PII S0040403901023152
Pfeifer, G.P., (1996) Technologies for Detection of DNA Damage and Mutations, , Plenum, New York
Rosenbohm, C., Pedersen, D.S., Frieden, M., Jensen, F.R., Arent, S., Larsen, S., Koch, T., LNA guanine and 2,6-diaminopurine. Synthesis, characterization and hybridization properties of LNA 2,6-diaminopurine containing oligonucleotides (2004) Bioorganic and Medicinal Chemistry, 12 (9), pp. 2385-2396. , DOI 10.1016/j.bmc.2004.02.008, PII S0968089604001154
Sakakura, A., Hayakawa, Y., A novel synthesis of oligonucleotide-peptide conjugates with a base- labile phosphate linker between the two components according to the allyl- protected phosphoramidite strategy (2000) Tetrahedron, 56 (26), pp. 4427-4435. , PII S0040402000003768
Socher, E., Bethge, L., Knoll, A., Jungnick, N., Herrmann, A., Seitz, O., Low-noise stemless PNA beacons for sensitive DNA and RNA detection (2008) Angew Chem Int Ed, 47, pp. 9555-9559
Stetsenko, D.A., Lubyako, E.N., Potapov, V.K., Azhikina, T.L., Sverdlov, E.D., New approach to solid phase synthesis of polyamide nucleic acids analogues (PNA) and PNA-DNA conjugates (1996) Tetrahedron Letters, 37 (20), pp. 3571-3574. , DOI 10.1016/0040-4039(96)00624-7
Stetsenko, D.A., Malakhov, A.D., Gait, M.J., Total stepwise solidphase synthesis of oligonucleotide-(30-N)-peptide conjugates (2002) Org Lett, 4, pp. 3259-3262
Tan, W., Fang, X., Li, J., Liu, X., Molecular beacons: A novel DNA probe for nucleic acid and protein studies (2000) Chem Eur J, 6, pp. 1107-1111
Taylor, G.R., (1997) Laboratory Methods for the Detection of Mutations and Polymorphisms in DNA, , CRC, Boca Raton
Truffert, J.-C., Asseline, U., Brack, A., Thuong, N.T., Synthesis, purification and characterization of two peptide- oligonucleotide conjugates as potential artificial nucleases (1996) Tetrahedron, 52 (8), pp. 3005-3016. , DOI 10.1016/0040-4020(96)00018-X
Tyagi, S., Kramer, F.R., Molecular beacons: Probes that fluoresce upon hybridization (1996) Nat Biotechnol, 14, pp. 303-308
Tyagi, S., Bratu, D.P., Kramer, F.R., Multicolor molecular beacons for allele discrimination (1998) Nature Biotechnology, 16 (1), pp. 49-53. , DOI 10.1038/nbt0198-49
Uhlmann, E., Peyman, A., Breipohl, G., Will, D.W., PNA: Synthetic polyamide nucleic acids with unusual binding properties (1998) Angew Chem Int Ed, 37, pp. 2797-2823
Uhlmann, E., Greiner, B., Breipohl, G., PNA/DNA chimeras (1999) Peptide Nucleic Acids, Protocols and Applications, p. 51. , Nielsen PE, Egholm M (eds). Horizon Scientific Press, Norfolk
Valis, L., Amann, N., Wagenknecht, H.-A., Detection of single base mismatches and abasic sites using phenanthridinium as an artificial DNA base and charge donor (2005) Organic and Biomolecular Chemistry, 3 (1), pp. 36-38. , DOI 10.1039/b414672g
Van Der Laan, A.C., Meeuwenoord, N.J., Kuyl-Yeheskiely, E., Oosting, R.S., Brands, R., Van Boom, J.H., Solid support synthesis of a PNA-DNA hybrid (1995) Recl Trav Chim Pays Bas, 114, pp. 295-297
Vinyak, R., Synthesis of PNA-DNA chimera by MMT chemistry (1999) Peptide Nucleic Acids, Protocols and Applications, p. 71. , Nielsen PE, Egholm M (eds), Horizon Scientific Press, Norfolk
Vives, E., Lebleu, B., Selective coupling of a highly basic peptide to an oligonucleotide (1997) Tetrahedron Letters, 38 (7), pp. 1183-1186. , DOI 10.1016/S0040-4039(97)00059-2, PII S0040403997000592
Zatsepin, T.S., Stetsenko, D.A., Arzumanov, A.A., Romanova, E.A., Gait, M.J., Oretskaya, T.S., Synthesis of peptide-oligonucleotide conjugates with single and multiple peptides attached to 20-aldehydes through thiazolidine, oxime, and hydrazine linkages (2002) Bioconjugate Chemistry, 13 (4), pp. 822-830. , DOI 10.1021/bc020016+
Amino Acids (ISSN: 1438-2199, 0939-4451, 1438-2199electronic), 2010 May; 38(5): 1301-1309.
Export to BibTeX Export to EndNote
Paper type: Erratum, Research Support, Non-U. S. Gov'T, Priority Journal Article,
Impact factor: 4.106, 5-year impact factor: 3.541
Url: http://www.scopus.com/inward/record.url?eid=2-s2.0-77955860234&partnerID=40&md5=7729b91d30fef82f1c0613384bae417b
Keywords: Amino Acids, Dna Recognition, Molecular Beacon, Protecting Groups, Alpha Amino Acid, Monomer, N Alpha (4 Methoxyphenyldiphenylmethyl) Beta [n2 (isobutyryl)guanin 9 Yl]alanine, N Alpha (4 Monomethoxytrityl) Beta [n4 (4 Tert Butylbenzoyl)cytosin 1 Yl]alanine, N Alpha (4 Monomethoxytrityl) Beta [n6 (anisoyl)adenin 9 Yl]alanine, N Alpha (4 Monomethoxytrityl) Beta [thymin 1 Yl]alanine, N Alpha Tert Butoxycarbonyl Beta [n2 (isobutyryl)guanin 9 Yl]alanine, N Alpha Tert Butoxycarbonyl Beta [n4 (4 Tert Butylbenzoyl)cytosin 1 Yl]alanine, N Alpha Tert Butoxycarbonyl Beta [n6 (anisoyl)adenin 9 Yl]alanine, Nucleic Acid Base, Peptide Nucleic Acid, Phosphoramidous Acid, Unclassified Drug, Amino Acid Synthesis, Article, Controlled Study, Diastereoisomer, Dna Alkylation, Dna Synthesis, Enantioselectivity, Molecular Recognition, Polymerization, Precipitation, Priority Journal, Racemization, Solid Phase Synthesis, Stoichiometry, Acylation, Chemistry, Electrospray Mass Spectrometry, Infrared Spectrophotometry, Nuclear Magnetic Resonance Spectroscopy, Stereoisomerism, Electrospray Ionization, Erratum, N Alpha (4 Methoxyphenyldiphenylmethyl) Beta [n2 (isobutyryl) Guanin 9 Yl] Alanine, N Alpha (4 Monomethoxytrityl) Beta [n4 (4 Tert Butylbenzoyl) Cytosin 1 Yl] Alanine, N Alpha (4 Monomethoxytrityl) Beta [n6 (anisoyl) Adenin 9 Yl] Alanine, N Alpha (4 Monomethoxytrityl) Beta [thymin 1 Yl] Alanine, N Alpha Tert Butoxycarbonyl Beta [n2 (isobutyryl) Guanin 9 Yl] Alanine, N Alpha Tert Butoxycarbonyl Beta [n4 (4 Tert Butylbenzoyl) Cytosin 1 Yl] Alanine, N Alpha Tert Butoxycarbonyl Beta [n6 (anisoyl) Adenin 9 Yl] Alanine,
Affiliations:
*** IBB - CNR ***
Institut fur Organische und Biomolekulare Chemie, Georg-August-Universitat Gottingen, Tammannstr. 2, 37077, Gottingen, Germany.
Institut Für Organische und Biomolekulare Chemie, Georg-August-Universität Göttingen, Tammannstr. 2, 37077 Göttingen, Germany
Istituto di Biostrutture e Bioimmagini-CNR, Via Mezzocannone 16, 80134 Naples, Italy
Institut F r Organische und Biomolekulare Chemie, Georg-August-Universit t G ttingen, Tammannstr. 2, 37077 G ttingen, Germany
References:
Antopolsky, M., Azhayev, A., Stepwise solid-phase synthesis of peptide-oligonucleotide conjugates on new solid supports (1999) Helvetica Chimica Acta, 82 (12), pp. 2130-2140. , DOI 10.1002/(SICI)1522-2675(19991215)82:12<2130::AID-HLCA2130> 3.0. CO
Arar, K., Aubertin, A.M., Roche, A.C., Monsigny, M., Mayer, R., Synthesis and antiviral activity of peptide-oligonucleotide conjugates prepared by using N-a-(bromoacetyl)peptides (1995) Bioconjug Chem, 6, pp. 573-577
Arnold, L.D., Kalantar, T.H., Vederas, J.C., Conversion of serine to stereochemically pure β-substituted α-amino acids via β-lactones (1985) Journal of the American Chemical Society, 107 (24), pp. 7105-7109. , DOI 10.1021/ja00310a058
Bergmann, F., Bannwarth, W., Solid phase synthesis of directly linked peptide-oligodeoxynucleotide hybrids using standard synthesis protocols (1995) Tetrahedron Lett, 36, pp. 1839-1842
Breipohl, G., Will, D.W., Peyman, A., Uhlmann, E., Novel synthetic routes to PNA monomers and PNA-DNA linker molecules (1997) Tetrahedron, 53 (43), pp. 14671-14686. , DOI 10.1016/S0040-4020(97)01044-2, PII S0040402097010442
Canle, M.L., Clegg, W., Demirtas, I., Elsegood, M.R.J., Maskill, H., Preparations, X-ray crystal structure determinations, and base strength measurements of substituted tritylamines (2000) Journal of the Chemical Society. Perkin Transactions 2, (1), pp. 85-92
Didenko, V.V., (2002) Situ Detection of DNA Damage: Methods and Protocols, , Humana Press, Totowa
Diederichsen, U., Pairing properties of alanyl peptide nucleic acids containing an amino acid backbone with alternating configuration (1996) Angew Chem Int Ed Engl, 35, pp. 445-448
Diederichsen, U., Alanyl-PNA: Evidence for linear band structures based on guanine-cytosine base pairs (1997) Angew Chem Int Ed Engl, 36, pp. 1886-1889
Diederichsen, U., Weicherding, D., Interactions of amino acid side chains with nucleobases in alanyl-PNA (1999) Synlett, (SPEC. ISSUE), pp. 917-920
Ede, N.J., Tregear, G.W., Haralambidis, J., Routine preparation of thiol oligonucleotides: Application to the synthesis of oligonucleotide- peptide hybrids (1994) Bioconjug Chem, 5, pp. 373-378
Ficht, S., Mattes, A., Seitz, O., Single-nucleotide-specific PNA-peptide ligation on synthetic and PCR DNA templates (2004) Journal of the American Chemical Society, 126 (32), pp. 9970-9981. , DOI 10.1021/ja048845o
Forget, D., Boturyn, D., Defrancq, E., Lhomme, J., Dumy, P., Highly efficient synthesis of peptide-oligonucleotide conjugates: Chemoselective oxime and thiazolidine formation (2001) Chemistry - A European Journal, 7 (18), pp. 3976-3984. , DOI 10.1002/1521-3765(20010917)7:18<3976::AID-CHEM3976> 3.0.CO
Harrison, J.G., Balasubramanian, S., Synthesis and hybridization analysis of a small library of peptide-oligonucleotide conjugates (1998) Nucleic Acids Research, 26 (13), pp. 3136-3145. , DOI 10.1093/nar/26.13.3136
Howarth, N.M., Wakelin, L.P.G., α-PNA: A Novel Peptide Nucleic Acid Analogue of DNA (1997) Journal of Organic Chemistry, 62 (16), pp. 5441-5450
Knemeyer, J.-P., Marme, N., Sauer, M., Probes for detection of specific DNA sequences at the single-molecule level (2000) Analytical Chemistry, 72 (16), pp. 3717-3724. , DOI 10.1021/ac000024o
Kostrikis, L.G., Tyagi, S., Mhlanga, M.M., Ho, D.D., Kramer, F.R., Spectral genotyping of human alleles (1998) Science, 279 (5354), pp. 1228-1229. , DOI 10.1126/science.279.5354.1228
Timar, Z., Kovacs, L., Kovacs, G., Schmel, Z., Fmoc/Acyl protecting groups in the synthesis of polyamide (peptide) nucleic acid monomers (2000) Journal of the Chemical Society, Perkin Transactions 1, (1), pp. 19-26
Kranaster, R., Ketzer, P., Marx, A., Mutant DNA polymerase for improved detection of single-nucleotide variations in microarrayed primer extension (2008) Chembiochem, 9, pp. 694-697
Küsel, A., Zhang, J., Alvarino Gil, M., Stückl, C.A., Meyer-Klaucke, W., Meyer, F., Diederichsen, U., Metal binding within a peptidebased nucleobase stack with tuneable double strand topology (2005) Eur J Inorg Chem, 431, pp. 7-4324
Li, J.J., Fang, X., Schuster, S.M., Tan, W., Molecular beacons: A novel approach to detect protein - DNA interactions (2000) Angewandte Chemie - International Edition, 39 (6), pp. 1049-1052. , DOI 10.1002/(SICI)1521-3773(20000317)39:6<1049::AID-ANIE1049> 3.0. CO
Lohse, P., Oberhauser, B., Oberhauser-Hofbauer, B., Baschang, G., Eschenmoser, A., Chemie von α-Aminonitrilen. XVII. Oligo(nukleodipeptamidinium)- Salze (1996) Croatica Chemica Acta, 69 (2), pp. 535-562
Mamos, P., Sanida, C., Barlos, K., Preparation of N-tritylamino acids from N-trimethylsilylamino acid trimethylsilyl esters (1988) Liebigs Ann Chem, pp. 1083-1084
Matsuo, T., In situ visualization of messenger RNA for basic fibroblast growth factor in living cells (1998) Biochimica et Biophysica Acta - General Subjects, 1379 (2), pp. 178-184. , DOI 10.1016/S0304-4165(97)00090-1, PII S0304416597000901
McMinn, D.L., Greenberg, M.M., Convergent solution-phase synthesis of a nucleopeptide using a protected oligonucleotide (1999) Bioorganic and Medicinal Chemistry Letters, 9 (4), pp. 547-550. , DOI 10.1016/S0960-894X(99)00051-7, PII S0960894X99000517
Musumeci, D., Roviello, G.N., Valente, M., Sapio, R., Pedone, C., Bucci, E.M., New synthesis of PNA-30DNA linker monomers, useful building blocks to obtain PNA/DNA chimeras (2004) Biopolymers - Peptide Science Section, 76 (6), pp. 535-542. , DOI 10.1002/bip.20135
Ollivier, N., Olivier, C., Gouyette, C., Huynh-Dinh, T., Gras-Masse, H., Melnyk, O., Synthesis of oligonucleotide-peptide conjugates using hydrazone chemical ligation (2002) Tetrahedron Letters, 43 (6), pp. 997-999. , DOI 10.1016/S0040-4039(01)02315-2, PII S0040403901023152
Pfeifer, G.P., (1996) Technologies for Detection of DNA Damage and Mutations, , Plenum, New York
Rosenbohm, C., Pedersen, D.S., Frieden, M., Jensen, F.R., Arent, S., Larsen, S., Koch, T., LNA guanine and 2,6-diaminopurine. Synthesis, characterization and hybridization properties of LNA 2,6-diaminopurine containing oligonucleotides (2004) Bioorganic and Medicinal Chemistry, 12 (9), pp. 2385-2396. , DOI 10.1016/j.bmc.2004.02.008, PII S0968089604001154
Sakakura, A., Hayakawa, Y., A novel synthesis of oligonucleotide-peptide conjugates with a base- labile phosphate linker between the two components according to the allyl- protected phosphoramidite strategy (2000) Tetrahedron, 56 (26), pp. 4427-4435. , PII S0040402000003768
Socher, E., Bethge, L., Knoll, A., Jungnick, N., Herrmann, A., Seitz, O., Low-noise stemless PNA beacons for sensitive DNA and RNA detection (2008) Angew Chem Int Ed, 47, pp. 9555-9559
Stetsenko, D.A., Lubyako, E.N., Potapov, V.K., Azhikina, T.L., Sverdlov, E.D., New approach to solid phase synthesis of polyamide nucleic acids analogues (PNA) and PNA-DNA conjugates (1996) Tetrahedron Letters, 37 (20), pp. 3571-3574. , DOI 10.1016/0040-4039(96)00624-7
Stetsenko, D.A., Malakhov, A.D., Gait, M.J., Total stepwise solidphase synthesis of oligonucleotide-(30-N)-peptide conjugates (2002) Org Lett, 4, pp. 3259-3262
Tan, W., Fang, X., Li, J., Liu, X., Molecular beacons: A novel DNA probe for nucleic acid and protein studies (2000) Chem Eur J, 6, pp. 1107-1111
Taylor, G.R., (1997) Laboratory Methods for the Detection of Mutations and Polymorphisms in DNA, , CRC, Boca Raton
Truffert, J.-C., Asseline, U., Brack, A., Thuong, N.T., Synthesis, purification and characterization of two peptide- oligonucleotide conjugates as potential artificial nucleases (1996) Tetrahedron, 52 (8), pp. 3005-3016. , DOI 10.1016/0040-4020(96)00018-X
Tyagi, S., Kramer, F.R., Molecular beacons: Probes that fluoresce upon hybridization (1996) Nat Biotechnol, 14, pp. 303-308
Tyagi, S., Bratu, D.P., Kramer, F.R., Multicolor molecular beacons for allele discrimination (1998) Nature Biotechnology, 16 (1), pp. 49-53. , DOI 10.1038/nbt0198-49
Uhlmann, E., Peyman, A., Breipohl, G., Will, D.W., PNA: Synthetic polyamide nucleic acids with unusual binding properties (1998) Angew Chem Int Ed, 37, pp. 2797-2823
Uhlmann, E., Greiner, B., Breipohl, G., PNA/DNA chimeras (1999) Peptide Nucleic Acids, Protocols and Applications, p. 51. , Nielsen PE, Egholm M (eds). Horizon Scientific Press, Norfolk
Valis, L., Amann, N., Wagenknecht, H.-A., Detection of single base mismatches and abasic sites using phenanthridinium as an artificial DNA base and charge donor (2005) Organic and Biomolecular Chemistry, 3 (1), pp. 36-38. , DOI 10.1039/b414672g
Van Der Laan, A.C., Meeuwenoord, N.J., Kuyl-Yeheskiely, E., Oosting, R.S., Brands, R., Van Boom, J.H., Solid support synthesis of a PNA-DNA hybrid (1995) Recl Trav Chim Pays Bas, 114, pp. 295-297
Vinyak, R., Synthesis of PNA-DNA chimera by MMT chemistry (1999) Peptide Nucleic Acids, Protocols and Applications, p. 71. , Nielsen PE, Egholm M (eds), Horizon Scientific Press, Norfolk
Vives, E., Lebleu, B., Selective coupling of a highly basic peptide to an oligonucleotide (1997) Tetrahedron Letters, 38 (7), pp. 1183-1186. , DOI 10.1016/S0040-4039(97)00059-2, PII S0040403997000592
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Synthesis of novel MMT/acyl-protected nucleo alanine monomers for the preparation of DNA/alanyl-PNA chimeras
Alanyl-peptide nucleic acid (alanyl-PNA)/DNA chimeras are oligomers envisaged to be beneficial in efficient DNA diagnostics based on an improved molecular beacon concept. A synthesis of alanyl-PNA/DNA chimera can be based on the solid phase assembly of the oligomer with mixed oligonucleotide/peptide backbone under DNA synthesis conditions, in which the nucleotides are introduced as phosphoramidites, whereas the nucleo amino acids make use of the acid labile monomethoxytrityl (MMT) group for temporary protection of the alpha-amino groups and acyl protecting groups for the exocyclic amino functions of the nucleobases. In this work, we realized for the first time the synthesis of all four MMT/acyl-protected nucleo alanines, achieved by deprotection/reprotection of the newly synthesized Boc/acyl intermediates, useful monomers for the obtainment of (alanyl-PNA)/DNA chimeras by conditions fully compatible with the standard phosphoramidite DNA synthesis strategy.
Alanyl-peptide nucleic acid (alanyl-PNA)/DNA chimeras are oligomers envisaged to be beneficial in efficient DNA diagnostics based on an improved molecular beacon concept. A synthesis of alanyl-PNA/DNA chimera can be based on the solid phase assembly of the oligomer with mixed oligonucleotide/peptide backbone under DNA synthesis conditions, in which the nucleotides are introduced as phosphoramidites, whereas the nucleo amino acids make use of the acid labile monomethoxytrityl (MMT) group for temporary protection of the alpha-amino groups and acyl protecting groups for the exocyclic amino functions of the nucleobases. In this work, we realized for the first time the synthesis of all four MMT/acyl-protected nucleo alanines, achieved by deprotection/reprotection of the newly synthesized Boc/acyl intermediates, useful monomers for the obtainment of (alanyl-PNA)/DNA chimeras by conditions fully compatible with the standard phosphoramidite DNA synthesis strategy.
Synthesis of novel MMT/acyl-protected nucleo alanine monomers for the preparation of DNA/alanyl-PNA chimeras
Synthesis of novel MMT/acyl-protected nucleo alanine monomers for the preparation of DNA/alanyl-PNA chimeras
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Roviello GN, Gröschel S, Pedone C, Diederichsen U
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Esposito S, Baglivo I, Malgieri G, Russo L, Zaccaro L, D'Andrea LD, Mammucari M, Di Blasio B, Isernia C, Fattorusso R, Pedone PV
* A novel type of zinc finger DNA binding domain in the Agrobacterium tumefaciens transcriptional regulator Ros (739 views)
Biochemistry (ISSN: 0006-2960, 1520-4995, 1520-4995electronic), 2006 Sep 29; 45(34): 10394-10405.
Impact Factor: 3.633
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Alterio V, Vitale RM, Monti SM, Pedone C, Scozzafava A, Cecchi A, De Simone G, Supuran CT
* Carbonic anhydrase inhibitors: X-ray and molecular modeling study for the interaction of a fluorescent antitumor sulfonamide with isozyme II and IX (507 views)
J Am Chem Soc (ISSN: 0002-7863, 0002-2786, 1520-5126), 2006 Jun 28; 128(25): 8329-8335.
Impact Factor: 7.696
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Galdiero S, Vitiello M, Amodeo P, D'Isanto M, Cantisani M, Pedone C, Galdiero M
* Structural requirements for proinflammatory activity of porin P2 loop 7 from Haemophilus influenzae (575 views)
Biochemistry (ISSN: 0006-2960, 1520-4995, 1520-4995electronic), 2006 Apr 11; 45(14): 4491-4501.
Impact Factor: 3.633
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Cappiello M, Alterio V, Amodeo P, Del Corso A, Scaloni A, Pedone C, Moschini R, De Donatis GM, De Simone G, Mura U
* A new spot test for sulfhydryl-containing compounds (454 views)
Anal Biochem, 2006 Mar 14; 79(1-2): 610-611.
Impact Factor: 2.305
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Cappiello M, Alterio V, Amodeo P, Del Corso A, Scaloni A, Pedone C, Moschini R, De Donatis GM, De Simone G, Mura U
* Metal ion substitution in the catalytic site greatly affects the binding of sulfhydryl-containing compounds to leucyl aminopeptidase (769 views)
Biochemistry (ISSN: 0006-2960, 1520-4995, 1520-4995electronic), 2006 Mar 14; 45(10): 3226-3234.
Impact Factor: 3.633
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Arena G, Casnati A, Contino A, Magrì A, Sansone F, Sciotto D, Ungaro R
* Inclusion of naturally occurring amino acids in water soluble calix[4]arenes: A microcalorimetric and 1H NMR investigation supported by molecular modeling (390 views)
Org Biomol Chem (ISSN: 1477-0520, 1477-0539, 1477-0539electronic), 2006 Jan 21; 4(2): 243-249.
Impact Factor: 2.874
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De Luca S, Della Moglie R, De Capua A, Morelli G
* New synthetic strategy for o-NBS protected amino acids and their use in synthesis of mono-benzylated peptides (455 views)
Tetrahedron Lett (ISSN: 0040-4039), 2005 Sep 26; 46(39): 6637-6640.
Impact Factor: 2.477
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Improta R, Antonello S, Formaggio F, Maran F, Rega N, Barone V
* Understanding Electron Transfer across Negatively-Charged Aib Oligopeptides (648 views)
J Phys Chem B (ISSN: 1520-6106, 1520-5207, 1520-5207electronic), 2005 Jan 20; 109(2): 1023-1033.
Impact Factor: 4.033
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Falcigno L, Oliva R, D'Auria G, Maletta M, Dettin M, Pasquato A, Di Bello C, Paolillo L
* Structural investigation of the HIV-1 envelope glycoprotein gp160 cleavage site 3: Role of site-specific mutations (437 views)
Chembiochem (ISSN: 1439-4227, 1439-7633, 1439-7633electronic), 2004 Dec 3; 5(12): 1653-1661.
Impact Factor: 3.474
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Merlino A, Graziano G, Mazzarella L
* Structural And Dynamic Effects Of Alpha-Helix Deletion In Sso7d: Implications For Protein Thermal Stability (423 views)
Proteins (ISSN: 0887-3585, 1097-0134, 1097-0134electronic), 2004 Dec 1; 57(4): 692-701.
Impact Factor: 4.429
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Cucinotta V, Giuffrida A, La Mendola D, Maccarrone G, Puglisi A, Rizzarelli E, Vecchio G
* 3-Amino Derivative Of Beta-Cyclodextrin: Thermodynamics Of Copper (ii) Complexes And Exploitation Of Its Enantioselectivity In The Separation Of Amino Acid Racemates By Ligand Exchange Capillary Electrophoresis (350 views)
And Life Sciencesjournal Of Chromatography B Analytical Technologies In The Biomedical, 2004 Feb 5; 800(1-2): 127-133.
Impact Factor: 1.403
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Rossi F, Zanotti G, Saviano M, Iacovino R, Palladino P, Saviano G, Amodeo P, Tancredi T, Laccetti P, Corbier C, Benedetti E
* New antitumour cyclic astin analogues: Synthesis, conformation and bioactivity (454 views)
J Pept Sci (ISSN: 1075-2617, 1099-1387, 1075-2617print), 2004 Feb; 10(2): 92-102.
Impact Factor: 1.652
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Zarivach R, Bashan A, Berisio R, Harms J, Auerbach T, Schluenzen F, Bartels H, Baram D, Pyetan E, Sittner A, Amit M, Hansen HAS, Kessler M, Liebe C, Wolff A, Agmon I, Yonath A
* Functional aspects of ribosomal architecture: Symmetry, chirality and regulation (504 views)
J Phys Org Chem (ISSN: 0894-3230), 2004; 17(11): 901-912.
Impact Factor: 1.211
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Isernia C, Bucci E, Leone M, Zaccaro L, Di Lello P, Digilio G, Esposito S, Saviano M, Di Blasio B, Pedone C, Pedone PV, Fattorusso R
* NMR structure of the single QALGGH zinc finger domain from the Arabidopsis thaliana SUPERMAN protein (430 views)
Chembiochem (ISSN: 1439-4227, 1439-7633, 1439-7633electronic), 2003 Mar 3; 4(2-3): 171-180.
Impact Factor: 3.992
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Formaggio F, Crisma M, Toniolo C, Broxterman QB, Kaptein B, Corbier C, Saviano M, Palladino P, Benedetti E
* Cα-Methyl, Cα-n-Propylglycine Homo-oligomers (321 views)
Macromolecules (ISSN: 0024-9297), 2003; 36(21): 8164-8170.
Impact Factor: 3.621
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D'Amore M, Improta R, Barone V
* Conformational behavior and magnetic properties of a nitroxide amino acid derivative in vacuo and in aqueous solution (238 views)
J Phys Chem A (ISSN: 1089-5639, 1520-5215electronic), 2003; 107(32): 6264-6269.
Impact Factor: 2.792
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Peggion C, Formaggio F, Crisma M, Toniolo C, Jimenez AI, Cativiela C, Kaptein B, Broxterman QB, Saviano M, Benedetti E
* Folding of peptides characterized by c3Val, a highly constrained analogue of valine (429 views)
Biopolymers (ISSN: 0006-3525, 0006-6352, 0006-3525print), 2003; 68(2): 178-191.
Impact Factor: 2.733
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Formaggio F, Bonchio M, Crisma M, Peggion C, Mezzato S, Polese A, Barazza A, Antonello S, Maran F, Broxterman QB, Kaptein B, Kamphuis J, Vitale RM, Saviano M, Benedetti E, Toniolo C
* Nitroxyl peptides as catalysts of enantioselective oxidations (498 views)
Chemistry (ISSN: 0947-6539, 1521-3765, 1521-3765electronic), 2002; 8(1): [d]84-93.
Impact Factor: 4.238
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De Falco S, Ruvoletto MG, Verdoliva A, Ruvo M, Raucci A, Marino M, Senatore S, Cassani G, Alberti A, Pontisso P, Fassina G
* Cloning and Expression of a Novel Hepatitis B Virus-binding Protein from HepG2 Cells (628 views)
Jbc Papers (ISSN: 0021-9258, 1083-351x, 0021-9258linking), 2001 Sep 28; 276(39): 36613-36623.
Impact Factor: 7.258
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Romanelli A, Garella I, Menchise V, Iacovino R, Saviano M, Montesarchio D, Didierjean C, Lello PD, Rossi F, Benedetti E
* Crystal-state conformation of Cα, α-dialkylated peptides containing chiral β-homo-residues (519 views)
J Pept Sci (ISSN: 1075-2617, 1099-1387, 1075-2617print), 2001; 7(1): 15-26.
Impact Factor: 1.451
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Pavone V, Lombardi A, Saviano M, De Simone G, Nastri F, Maglio O, Omote Y, Yamanaka Y, Yamada T
Conformational behavior of C(α, α)-diphenyl glycine: Extended conformation in tripeptides containing consecutive Dφg residues (408 views)
Biopolymers (ISSN: 0006-3525, 0006-6352, 0006-3525print), 2000 Feb; 53(2): 161-168.
Impact Factor: 2.405
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De Simone G, Lombardi A, Galdiero S, Nastri F, Di Costanzo L, Gohda S, Sano A, Yamada T, Pavone V
The crystal structure of a Dcp-containing peptide (456 views)
Biopolymers (ISSN: 0006-3525, 0006-6352, 0006-3525print), 2000 Feb; 53(2): 182-188.
Impact Factor: 2.405
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Lombardi A, De Simone G, Galdiero S, Nastri F, Di Costanzo L, Makihiara K, Yamada T, Pavone V
The crystal structure of Afc-containing peptide (473 views)
Biopolymers (ISSN: 0006-3525, 0006-6352, 0006-3525print), 2000 Feb; 53(2): 150-160.
Impact Factor: 2.405
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Caliendo G, Fiorino F, Grieco P, Perissutti E, De Luca S, Giuliano A, Santelli G, Califano D, Severino B, Santagada V
Synthesis and biological activity of pseudopeptides inhibitors of Ras farnesyl transferase containing unconventional amino acids (549 views)
Farmaco (ISSN: 0014-827x), 1999 Nov; 54(11-12): 785-790.
Impact Factor: 0.406
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Pavone V, Lombardi A, Saviano M, Nastri F, Zaccaro L, Maglio O, Pedone C, Omote Y, Yamanaka Y, Yamada T
Conformational Behaviour Of C (alpha, Alpha)-Diphenylglycine: Folded Vs. Extended Structures In Dphig-Containing Tripeptides (454 views)
J Pept Sci (ISSN: 1075-2617, 1099-1387, 1075-2617print), 1998 Feb; 4(1): 21-32.
Impact Factor: 1.311
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Campagna T, Grasso G, Rizzarelli E, Vecchio G
L- and D-cysteine derivatives of β-cyclodextrin: Different molecular recognition properties of their copper(II) complexes for amino acids (363 views)
Inorg Chim Acta (ISSN: 0020-1693), 1998; 275-276: 395-400.
Impact Factor: 1.454
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Benedetti E, Iacovino R, Pedone C, Rossi F, Saviano M, Isernia C, Montesarchio D, DeNapoli L, Piccialli G
β-Amino acid residues: Conformational characterization of an N- and C-protected homo-β-(S)-leucine (314 views)
Int J Pept Res Ther (ISSN: 0929-5666, 1573-3149), 1997 Jun; 4(3): 129-134.
Impact Factor: 0.557
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Bonomo RP, Cucinotta V, D'Alessandro F, Impellizzeri G, Maccarrone G, Rizzarelli E, Vecchio G, Carima L, Corradini R, Sartor G, Marchelli R
Chiral recognition by the copper(ii) complex of 6-deoxy-6-n-(2 - methylaminopyridine)-β-cyclodextrin (381 views)
Chirality (ISSN: 0899-0042), 1997; 9(4): 341-349.
Impact Factor: 1.915
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Crisma M, Formaggio F, Valle G, Toniolo C, Saviano M, Iacovino R, Zaccaro L, Benedetti E
Experimental evidence at atomic resolution for intramolecular N- H···π (phenyl) interactions in a family of amino acid derivatives (418 views)
Biopolymers (ISSN: 0006-3525, 0006-6352, 0006-3525print), 1997; 42(1): 1-6.
Impact Factor: 2.425
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Bonomo RP, Pedotti S, Vecchio G, Rizzarelli E
Molecular Recognition of Amino Acids by Copper(II) Complexes of 6A, 6X-Diamino-6A, 6 X-dideoxy-β-cyclodextrin (X = B, C, D) (254 views)
Inorg Chem (ISSN: 0020-1669, 1520-510x, 1520-510xelectronic), 1996 Nov 6; 35(23): 6873-6877.
Impact Factor: 2.736
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Lombardi A, D'Auria G, Saviano M, Maglio O, Nastri F, Quartara L, Pedone C, Pavone V
Bicyclic Peptides As Type I/Type Ii Beta-Turn Scaffolds (514 views)
Biopolym Pept Sci Sect, 1996; 40(5): 505-518.
Impact Factor: 0
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Rossi F, Saviano M, Di Talia P, Di Blasio B, Pedone C, Zanotti G, Mosca M, Saviano G, Tancredi T, Ziegler K, Benedetti E
Solution and solid state structure of an aib-containing cyclodecapeptide inhibiting the cholate uptake in hepatocytes (455 views)
Biopolymers (ISSN: 0006-3525, 0006-6352, 0006-3525print), 1996; 40(5): 465-478.
Impact Factor: 2.425
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Pavone V, Lombardi A, Saviano M, Di Blasio B, Nastri F, Fattorusso R, Zaccaro L, Maglio O, Yamada T, Omote Y
Mixed conformation in C(α, α)-disubstituted tripeptides: X-ray crystal structures of Z-Aib-Dph-Gly-OMe and Bz-Dph-Dph-Gly-OMe (401 views)
Biopolymers (ISSN: 0006-3525, 0006-6352, 0006-3525print), 1994 Dec; 34(12): 1595-1604.
Impact Factor: 2.425
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Zanotti G, Maione A, Rossi F, Saviano M, Pedone C, Tancredi T
BIOACTIVE PEPTIDES - CONFORMATIONAL STUDY OF A CYSTINYL CYCLOHEPTAPEPTIDE IN ITS FREE AND CALCIUM COMPLEXED FORMS (581 views)
Biopolymers (ISSN: 0006-3525, 0006-6352, 0006-3525print), 1993 Jul; 33(7): 1083-1091.
Impact Factor: 2.425
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Arena G, Bindoni M, Cardile V, Maccarrone G, Riello MC, Rizzarelli E, Sciuto S
Cytotoxic and cytostatic activity of copper(II) complexes. Importance of the speciation for the correct interpretation of the in vitro biological results (478 views)
J Chem Res (ISSN: 0162-0134, 1873-3344, 0162-0134print), 1993 Apr 1; 50(1): 31-45.
Impact Factor: 1.342
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Pavone V, Di Blasio B, Lombardi A, Maglio O, Isernia C, Pedone C, Benedetti E, Altmann E, Mutter M
Non coded C alpha, alpha-disubstituted amino acids. X-ray diffraction analysis of a dipeptide containing (S)-alpha-methylserine (370 views)
Int J Pept Protein Res (ISSN: 0367-8377, 0367-8377print, 0367-8377linking), 1993 Jan; 41(1): 15-20.
Impact Factor: 1.255
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Lombardi A, Maglio O, Pavone B, Di Blasio V, Saviano M, Nastri F, Pedone C, Benedetti E
Pt(II) Complexes of Amino Acids and Peptides. III. X-Ray Diffraction Study of trans-[Cl-(Ph3P)-Pt-(H-Aib-O-)] (414 views)
Inorg Chim Acta, 1993; 204: 87-92.
Impact Factor: 0
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Lombardi A, Maglio O, Benedetti B, Di Blasio E, Saviano M, Nastri F, Pedone C, Pavone V
Pt(II) Complexes of Amino Acids and Peptides. II. Structural Analysis of trans-[Cl2-Pt-(H-Aib-OH)2] (429 views)
Inorg Chim Acta, 1992; 196: 241-246.
Impact Factor: 0
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Della Ragione F, Oliva A, Gragnaniello V, Russo GL, Palumbo R, Zappia V
Physicochemical and immunological studies on mammalian 5'-deoxy-5'-methylthioadenosine phosphorylase (26 views) (PDF 8 views)
J Biol Chem (ISSN: 0021-9258linking), 1990 Apr 15; 265(11): 6241-6246.
Impact Factor: 5.328
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Alberghina M, Brogna A, Mangiameli A, Marletta F, Rizzarelli E, Sammartano S
Copper(II) complexes of aminoacids: Gastric acid antisecretory activity in rats (2114 views)
Farmaco Ed Sci, 1982 Dec; 37(12): 805-814.
Impact Factor: 0
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* Synthesis, Characterization, and Study of Catalytic Activity of Chiral Cu(II) and Ni(II) Salen Complexes in the α-Amino Acid C-α Alkylation Reaction (7 views)
Molecules, 2023 Jan 25; 28: 1180-1196.
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Fik-jaskółka MA, Mkrtchyan AF, Saghyan AS, Palumbo R, Belter A, Hayriyan LA, Simonyan H, Roviello V, Roviello GN
* Spectroscopic and SEM evidences for G4-DNA binding by a synthetic alkyne-containing amino acid with anticancer activity (210 views) (PDF 75 views)
Spectrochim Acta A (ISSN: 1386-1425linking), 2020 Mar 15; 229: 117884-117884.
Impact Factor: 3.232
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Bocian A, Szymańska M, Brykczyńska D, Kubicki M, Wałęsa-chorab M, Roviello GN, Fik-jaskółka MA, Gorczyński A, Patroniak V
* New artificial biomimetic enzyme analogues based on iron(II/III) Schiff Base complexes: an effect of (benz)imidazole organic moieties on phenoxazinone synthase and DNA recognition (225 views)
Molecules (ISSN: 1420-3049linking, 1420-3049electronic), 2019 Aug 31; 24(17): 3173-3173.
Impact Factor: 3.06
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Vincenzi M, Mercurio FA, Leone M
* About TFE: Old and New Findings (101 views)
Curr Protein Pept Sci (ISSN: 1389-2037linking), 2019; 20 (5 ): 425-451.
Impact Factor: 3.011
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Angeli A, Buonanno M, Donald WA, Monti SM, Supuran CT
* The zinc - but not cadmium - containing zeta-carbonic from the diatom Thalassiosira weissflogii is potently activated by amines and amino acids (284 views)
Bioorg Chem (ISSN: 1090-2120electronic, 0045-2068linking), 2018 Oct; 80: 261-265.
Impact Factor: 3.929
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Roviello GN
* Novel insights into nucleoamino acids: biomolecular recognition and aggregation studies of a thymine-conjugated L-phenyl alanine (379 views)
Amino Acids (ISSN: 1438-2199electronic, 0939-4451linking), 2018 May 15; DOI10.1007/s00726-01: 933-941.
Impact Factor: 3.173
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Diana D, Di Salvo C, Celentano V, De Rosa L, Romanelli A, Fattorusso R, D'Andrea LD
* Conformational stabilization of a beta-hairpin through a triazole-tryptophan interaction (365 views)
Org Biomol Chem (ISSN: 1477-0539electronic, 1477-0520linking), 2018 Jan 31; 16(5): 787-795.
Impact Factor: 3.451
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Grage SL, Kara S, Bordessa A, Doan V, Rizzolo F, Putzu M, Kubar T, Papini AM, Chaume G, Brigaud T, Afonin S, Ulrich AS
* Orthogonal (19) F-Labeling for Solid-State NMR Spectroscopy Reveals the Conformation and Orientation of Short Peptaibols in Membranes (347 views)
Chemistry (ISSN: 1521-3765electronic, 0947-6539linking), 2018 Jan 11; N/D: N/D-N/D.
Impact Factor: 5.476
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Magri A, Pietropaolo A, Tabbì G, La Mendola D, Rizzarelli E
* From Peptide Fragments to Whole Protein: Copper(II) Load and Coordination Features of IAPP (600 views) (PDF 116 views)
Chemistry (ISSN: 0947-6539, 1521-3765, 1521-3765electronic), 2017 Dec 19; 23(71): 17898-17902.
Impact Factor: 5.16
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Depalo N, Corricelli M, De Paola I, Valente G, Iacobazzi RM, Altamura E, Debellis D, Comegna D, Fanizza E, Denora N, Laquintana V, Mavelli F, Striccoli M, Saviano M, Agostiano A, Del Gatto A, Zaccaro L, Curri ML
* NIR Emitting Nanoprobes Based on Cyclic RGD Motif Conjugated PbS Quantum Dots for Integrin-Targeted Optical Bioimaging (420 views) (PDF 184 views)
Acs Appl Mater Inter (ISSN: 1944-8244), 2017 Dec 13; 9(49): 43113-43126.
Impact Factor: 8.097
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Sgarlata C, Arena G, Bonomo RP, Giuffrida A, Tabbì G
* Simple and mixed complexes of copper(II) with 8-hydroxyquinoline derivatives and amino acids: Characterization in solution and potential biological implications (411 views) (PDF 160 views)
J Chem Res (ISSN: 0162-0134, 1873-3344, 0162-0134print), 2017 Dec 8; 180: 89-100.
Impact Factor: 3.063
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Magrì A, Tabbì G, Breglia R, De Gioia L, Fantucci P, Bruschi M, Bonomo RP, La Mendola D
* Copper ion interaction with the RNase catalytic site fragment of the angiogenin protein: an experimental and theoretical investigation (389 views) (PDF 179 views)
Dalton T (ISSN: 1477-9226, 1477-9234, 1477-9226linking), 2017 Jul 04; 46(26): 8524-8538.
Impact Factor: 4.099
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Calce E, De Luca S
* The Cysteine S-Alkylation Reaction as a Synthetic Method to Covalently Modify Peptide Sequences (400 views)
Chemistry (ISSN: 0947-6539, 1521-3765, 1521-3765electronic), 2016 Aug 19; 22: 1-11.
Impact Factor: 5.317
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La Mendola D, Arnesano F, Hansson O, Giacomelli C, Calo V, Mangini V, Magrì A, Bellia F, Trincavelli ML, Martini C, Natile G, Rizzarelli E
* Copper binding to naturally occurring, lactam form of angiogenin differs from that to recombinant protein, affecting their activity (407 views)
Metallomics (ISSN: 1756-5901, 1756-591x), 2016 Jan 20; 8(1): 118-124.
Impact Factor: 3.975
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Roviello GN, Vicidomini C, Di Gaetano S, Capasso D, Musumeci D, Roviello V
* Solid phase synthesis and RNA-binding activity of an arginine-containing nucleopeptide (402 views)
Rsc Adv (ISSN: 2046-2069), 2016; 6(17): 14140-14148.
Impact Factor: 3.108
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Roviello GN, Roviello V, Autiero I, Saviano M
* Solid phase synthesis of TyrT, a thymine-tyrosine conjugate with poly(A) RNA-binding ability (505 views)
Rsc Adv (ISSN: 2046-2069), 2016; 6(33): 27607-27613.
Impact Factor: 3.108
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Merlino F, Brancaccio D, Yousif AM, Piras L, Campiglia P, Gomez-monterrey I, Santicioli P, Meini S, Maggi CA, Novellino E, Carotenuto A, Grieco P
* Structure-Activity Study of the Peptides P5U and Urantide by the Development of Analogues Containing Uncoded Amino Acids at Position9 (378 views)
Chemmedchem (ISSN: 1860-7179, 1860-7187, 1860-7179linking), 2016; N/D: N/D-N/D.
Impact Factor: 3.225
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Cerutti E, Viale A, Nervi C, Gobetto R, Aime S
* The Role of the Amino Protecting Group during Parahydrogenation of Protected Dehydroamino Acids (215 views)
J Phys Chem A (ISSN: 1089-5639, 1520-5215electronic), 2015 Nov 19; 119(46): 11271-11279.
Impact Factor: 2.883
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Vitale R, Lista L, Cerrone C, Caserta G, Chino M, Maglio O, Nastri F, Pavone V, Lombardi A
* An artificial heme-enzyme with enhanced catalytic activity: evolution, functional screening and structural characterization (447 views)
Org Biomol Chem (ISSN: 1477-0520, 1477-0539, 1477-0539electronic), 2015 Apr 22; 13(17): 4859-4868.
Impact Factor: 3.559
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Guaragna A, Roviello GN, D'Errico S, Paolella C, Palumbo G, D'Alonzo D
* Solid phase synthesis of a novel folate-conjugated 5-aminolevulinic acid methyl ester based photosensitizer for selective photodynamic therapy (422 views)
Tetrahedron Lett (ISSN: 0040-4039), 2015 Feb 4; 56(6): 775-778.
Impact Factor: 2.347
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Troise AD, Fiore A, Roviello GN, Monti SM, Fogliano V
* Simultaneous quantification of amino acids and Amadori products in foods through ion-pairing liquid chromatography-high-resolution mass spectrometry (1375 views)
Amino Acids (ISSN: 0939-4451, 1438-2199, 1438-2199electronic), 2015 Jan; 47(1): 111-124.
Impact Factor: 3.196
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Caporale A, Selis F, Pain D, Sandomenico A, Jotti S, Tonon G, Ruvo M
* The LQSP tetrapeptide is a new highly efficient substrate of microbial transglutaminase for the site-specific derivatization of peptides and proteins (683 views)
Biotechnol J (ISSN: 1860-6768), 2015 Jan; 10(1): 154-161.
Impact Factor: 3.781
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Caso JV, Russo L, Palmieri M, Malgieri G, Galdiero S, Falanga A, Isernia C, Iacovino R
* Investigating the inclusion properties of aromatic amino acids complexing beta-cyclodextrins in model peptides (418 views)
Amino Acids (ISSN: 0939-4451, 1438-2199, 1438-2199electronic), 2015; N/D: N/D-N/D.
Impact Factor: 3.196
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Cohen SS, Riven I, Cortajarena AL, De Rosa L, D'Andrea LD, Regan L, Haran G
* Probing the molecular origin of native-state flexibility in repeat proteins (354 views)
J Am Chem Soc (ISSN: 0002-7863, 0002-2786, 0002-7863print), 2015; 137(32): 10367-10373.
Impact Factor: 13.038
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Sandomenico A, Celentano V, D'Andrea LD, Palmieri G, Ruvo M
* Screening of beta-hairpin peptide-engrafted 1, 2, 3-triazoles to identify APEH enzyme inhibitors (412 views)
Rsc Adv (ISSN: 2046-2069), 2015; 5(13): 9965-9972.
Impact Factor: 3.289
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Comegna D, de Paola I, Saviano M, Del Gatto A, Zaccaro L
* Straightforward entry to s-glycosylated fmoc-amino acids and their application to solid phase synthesis of glycopeptides and glycopeptidomimetics (490 views)
Org Lett (ISSN: 1523-7060, 1523-7052, 1523-7052electronic), 2015; 17(3): 640-643.
Impact Factor: 6.732
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Giuffrida A, Maccarrone G, Cucinotta V, Orlandini S, Contino A
* Recent advances in chiral separation of amino acids using capillary electromigration techniques (179 views)
J Chromatogr A (ISSN: 0021-9673, 0021-9673linking), 2014 Oct 10; 1363: 41-50.
Impact Factor: 4.169
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Scognamiglio PL, Di Natale C, Leone M, Poletto M, Vitagliano L, Tell G, Marasco D
* G-quadruplex DNA recognition by nucleophosmin: new insights from protein dissection (576 views)
Bba-Gen Subjects (ISSN: 0005-2728, 0006-3002print, 1570-9639print), 2014 Jun; 1840(6): 2050-2059.
Impact Factor: 5.353
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Zanoli LM, Licciardello M, D'Agata R, Lantano C, Calabretta A, Corradini R, Marchelli R, Spoto G
* Peptide nucleic acid molecular beacons for the detection of PCR amplicons in droplet-based microfluidic devices (360 views)
Anal Bioanal Chem (ISSN: 1618-2642), 2013 Jan; 405(2-3): 615-624.
Impact Factor: 3.578
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Travaglia A, La Mendola D, Magrì A, Nicoletti VG, Pietropaolo A, Rizzarelli E
* Copper, BDNF and Its N-terminal domain: inorganic features and biological perspectives (522 views)
Chemistry (ISSN: 1521-3765, 0947-6539, 1521-3765electronic), 2012 Dec 3; 18(49): 15618-15631.
Impact Factor: 5.831
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Roviello GN, Musumeci D, Bucci EM, Pedone C
* Synthesis of a diaminopropanoic acid-based nucleoamino acid and assembly of cationic nucleopeptides for biomedical applications (444 views)
Amino Acids (ISSN: 0939-4451, 1438-2199, 1438-2199electronic), 2012 Dec; 43(6): 2537-2543.
Impact Factor: 3.914
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Di Maro A, Berisio R, Ruggiero A, Tamburino R, Severino V, Zacchia E, Parente A
* Structural and enzymatic properties of an in vivo proteolytic form of PD-S2, type 1 ribosome-inactivating protein from seeds of Phytolacca dioica (357 views)
Biochem Biophys Res Commun (ISSN: 0006-291x), 2012 May 11; 421(3): 514-520.
Impact Factor: 2.406
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Galdiero S, Russo L, Falanga A, Cantisani M, Vitiello M, Fattorusso R, Malgieri G, Galdiero M, Isernia C
* Structure and Orientation of the gH625-644 Membrane Interacting Region of Herpes Simplex Virus Type 1 in a Membrane Mimetic System (384 views)
Biochemistry (ISSN: 0006-2960, 1520-4995, 1520-4995electronic), 2012 Apr 10; 51(14): 3121-3128.
Impact Factor: 3.377
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Langlois C, Del Gatto A, Arseneault G, Lafrance-vanasse J, De Simone M, Morse T, De Paola I, Lussier-price M, Legault P, Pedone C, Zaccaro L, Omichinski JG
* Structure-based design of a potent artificial transactivation domain based on p53 (425 views)
J Am Chem Soc (ISSN: 1520-5126, 0002-2786, 0002-7863), 2012 Jan 25; 134(3): 1715-1723.
Impact Factor: 5.65
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Malgieri G, Zaccaro L, Leone M, Bucci E, Esposito S, Baglivo I, Del Gatto A, Russo L, Scandurra R, Pedone PV, Fattorusso R, Isernia C
* Zinc to Cadmium Replacement in the A. thaliana SUPERMAN Cys(2)His(2) Zinc Finger Induces Structural Rearrangements of Typical DNA Base Determinant Positions (445 views)
Biopolymers (ISSN: 0006-3525, 0006-6352, 0006-3525print), 2011 Nov; 95(11): 801-810.
Impact Factor: 2.87
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Kállay C, Dávid A, Timári S, Nagy EM, Sanna D, Garribba E, Micera G, De Bona P, Pappalardo G, Rizzarelli E, Sóvágó I
* Copper(II) complexes of rat amylin fragments (360 views)
Dalton T (ISSN: 1477-9234, 1477-9226, 1477-9234electronic), 2011 Oct 14; 40(38): 9711-9721.
Impact Factor: 3.838
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Monfregola L, De Luca S
* Synthetic strategy for side chain mono-N-alkylation of Fmoc-amino acids promoted by molecular sieves (538 views)
Amino Acids (ISSN: 0939-4451, 1438-2199, 1438-2199electronic), 2011 Oct; 41(4): 981-990.
Impact Factor: 3.248
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Roviello GN, Di Gaetano S, Capasso D, Franco S, Crescenzo C, Bucci EM, Pedone C
* RNA-binding and viral reverse transcriptase inhibitory activity of a novel cationic diamino acid-based peptide (610 views)
J Med Chem (ISSN: 0022-2623, 1520-4804, 0022-2623print), 2011 Apr 14; 54(7): 2095-2101.
Impact Factor: 5.248
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Vagliasindi LI, Arena G, Bonomo RP, Pappalardo G, Tabbì G
* Copper complex species within a fragment of the N-terminal repeat region in opossum PrP protein (357 views)
Dalton T (ISSN: 1477-9226, 1477-9234, 1477-9234electronic), 2011 Mar 21; 40(11): 2441-2450.
Impact Factor: 3.838
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Caraci F, Molinaro G, Battaglia G, Giuffrida ML, Riozzi B, Traficante A, Bruno V, Cannella M, Merlo S, Wang X, Heinz BA, Nisenbaum ES, Britton TC, Drago F, Sortino MA, Copani A, Nicoletti F
* Targeting group II Metabotropic Glutamate (mGlu) receptors for the treatment of psychosis associated with alzheimer's disease: Selective activation of mGlu2 receptors amplifies β-amyloid toxicity in cultured neurons, whereas dual activation of mGlu2 and mGlu3 receptors is neuroprotective (765 views)
Mol Pharmacol (ISSN: 0026-895x), 2011 Mar; 79(3): 618-626.
Impact Factor: 4.883
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Cucinotta V, Giuffrida A, Grasso G, MacCarrone G, Mazzaglia A, Messina M, Vecchio G
* Diaminotrehalose-capped β-cyclodextrin, a new member of hemispherodextrins: Synthesis, thermodynamic and spectroscopic characterization and its exploitation in chiral electrokinetic chromatography (400 views)
J Sep Sci (ISSN: 1615-9306), 2011 Jan; 34(1): 70-76.
Impact Factor: 2.733
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La Mendola D, Magrì A, Vagliasindi LI, Hansson Ö, Bonomo RP, Rizzarelli E
* Copper(II) complex formation with a linear peptide encompassing the putative cell binding site of angiogenin (449 views)
Dalton T (ISSN: 1477-9234, 1477-9226, 1477-9234electronic), 2010 Nov 28; 39(44): 10678-10684.
Impact Factor: 3.647
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Moccia M, Roviello GN, Bucci EM, Pedone C, Saviano M
* Synthesis of a l-lysine-based alternate alpha, epsilon-peptide: A novel linear polycation with nucleic acids-binding ability (465 views)
Int J Pharm (ISSN: 0378-5173, 1873-3476), 2010 Sep 15; 397(1-2): 179-183.
Impact Factor: 3.607
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Galdiero S, Falanga A, Vitiello M, Raiola L, Russo L, Pedone C, Isernia C, Galdiero M
* The presence of a single N-terminal histidine residue enhances the fusogenic properties of a Membranotropic peptide derived from herpes simplex virus type 1 glycoprotein (471 views)
Jbc Papers (ISSN: 1083-351x, 0021-9258, 0021-9258linking), 2010 May 28; 285(22): 17123-17136.
Impact Factor: 5.328
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Chambery A, Severino V, Di Maro A, D'Aniello A, Ruvo M, Parente A
* Quantification of thyrotropin-releasing hormone by liquid chromatography-electrospray mass spectrometry (487 views)
Amino Acids (ISSN: 0939-4451, 1438-2199, 1438-2199electronic), 2010 Apr; 38(4): 1031-1041.
Impact Factor: 4.106
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Alberobello AT, D'Esposito V, Marasco D, Doti N, Ruvo M, Bianco R, Tortora G, Esposito I, Fiory F, Miele C, Beguinot F, Formisano P
* Selective Disruption of Insulin-like Growth Factor-1 (IGF-1) Signaling via Phosphoinositide-dependent Kinase-1 Prevents the Protective Effect of IGF-1 on Human Cancer Cell Death (581 views)
Jbc Papers (ISSN: 0021-9258, 1083-351x, 0021-9258linking), 2010 Feb 26; 285(9): 6563-6572.
Impact Factor: 5.328
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Mazzaglia A, Micali N, Scolaro LM, Attanasio F, Magrí A, Pappalardo G, Villari V
* Aggregation properties of the peptide fragments derived from the 17-29 region of the human and rat IAPP: A comparative study with two PEG-conjugated variants of the human sequence (441 views)
J Phys Chem B (ISSN: 1520-6106, 1520-5207, 1520-5207electronic), 2010 Jan 21; 114(2): 705-713.
Impact Factor: 3.603
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Roviello GN, Gröschel S, Pedone C, Diederichsen U
* Erratum: Synthesis of novel MMT/acyl-protected nucleo alanine monomers for the preparation of DNA/alanyl-PNA chimeras (Amino Acids DOI: 10. 1007/s00726-009-0324-x) (312 views)
Amino Acids (ISSN: 0939-4451, 1438-2199, 1438-2199electronic), 2010; 38(5): 1311-1312.
Impact Factor: 4.106
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Merlino A, Russo Krauss I, Perillo M, Mattia CA, Ercole C, Picone D, Vergara A, Sica F
* Toward an Antitumor Form of Bovine Pancreatic Ribonuclease: The Crystal Structure of Three Noncovalent Dimeric Mutants (399 views)
Biopolymers (ISSN: 0006-3525, 0006-6352, 0006-3525print), 2009 Dec; 91(12): 1029-1037.
Impact Factor: 2.605
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Roviello GN, Musumeci D, Castiglione M, Bucci EM, Pedone C, Benedetti E
* Solid Phase Synthesis And Rna-Binding Studies Of A Serum-Resistant Nucleo-Epsilon-Peptide (435 views)
J Pept Sci (ISSN: 1075-2617, 1099-1387, 1075-2617print), 2009 Mar; 15(3): 155-160.
Impact Factor: 1.807
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Chiechio S, Zammataro M, Morales ME, Busceti CL, Drago F, Th Gereau RW, Copani A, Nicoletti F
* Epigenetic modulation of mGlu2 receptors by histone deacetylase inhibitors in the treatment of inflammatory pain (587 views)
Mol Pharmacol (ISSN: 0026-895x), 2009; 75(5): 1014-1020.
Impact Factor: 4.531
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Ponticelli S, Marasco D, Tarallo V, Albuquerque RJC, Mitola S, Takeda A, Stassen J, Presta M, Ambati J, Ruvo M, De Falco S
* Modulation of Angiogenesis by a Tetrameric Tripeptide That Antagonizes Vascular Endothelial Growth Factor Receptor (615 views)
Jbc Papers (ISSN: 0021-9258, 1083-351x, 0021-9258linking), 2008 Dec 5; 283(49): 34250-34259.
Impact Factor: 5.52
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Galdiero S, Falanga A, Vitiello M, Raiola L, Fattorusso R, Browne H, Pedone C, Isernia C, Galdiero M
* Analysis of a membrane interacting region of herpes simplex virus type 1 glycoprotein (632 views)
Jbc Papers (ISSN: 0021-9258, 1083-351x, 0021-9258linking), 2008 Oct 31; 283(44): 29993-30009.
Impact Factor: 5.52
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Pietropaolo A, Muccioli L, Zannoni C, La Mendola D, Maccarrone G, Pappalardo G, Rizzarelli E
* Unveiling the role of histidine and tyrosine residues on the conformation of the avian prion hexarepeat domain (343 views)
J Phys Chem B (ISSN: 1520-6106, 1520-5207, 1520-5207electronic), 2008 Apr 24; 112(16): 5182-5188.
Impact Factor: 4.189
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D'Andrea LD, Testa I, Panico M, Di Stasi R, Carac C, Tarallo L, Arra C, Barbieri A, Romanelli A, Aloj L
* In vivo and in vitro characterization of CCK8 bearing a histidine-based chelator labeled with Tc-99m-tricarbonyl (424 views)
Biopolymers (ISSN: 0006-3525, 0006-6352, 0006-3525print), 2008; 90(5): 707-712.
Impact Factor: 2.823
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Cucinotta V, Giuffrida A, Grasso G, Maccarrone G, Messina M, Vecchio G
* High selectivity in new chiral separations of dansyl amino acids by cyclodextrin derivatives in electrokinetic chromatography (290 views)
J Chromatogr A (ISSN: 0021-9673, 0021-9673linking), 2007; 1155(2): 172-179.
Impact Factor: 3.641
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Dalla Bona A, Formaggio F, Peggion C, Kaptein B, Broxterman Quirinus B, Galdiero S, Galdiero M, Vitiello M, Benedetti E, Toniolo C
* Synthesis, conformation, and bioactivity of novel analogues of the antiviral lipopeptide halovir (501 views)
J Pept Sci (ISSN: 1075-2617, 1099-1387, 1075-2617print), 2006 Dec; 12(12): 748-757.
Impact Factor: 1.801
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Esposito S, Baglivo I, Malgieri G, Russo L, Zaccaro L, D'Andrea LD, Mammucari M, Di Blasio B, Isernia C, Fattorusso R, Pedone PV
* A novel type of zinc finger DNA binding domain in the Agrobacterium tumefaciens transcriptional regulator Ros (739 views)
Biochemistry (ISSN: 0006-2960, 1520-4995, 1520-4995electronic), 2006 Sep 29; 45(34): 10394-10405.
Impact Factor: 3.633
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Alterio V, Vitale RM, Monti SM, Pedone C, Scozzafava A, Cecchi A, De Simone G, Supuran CT
* Carbonic anhydrase inhibitors: X-ray and molecular modeling study for the interaction of a fluorescent antitumor sulfonamide with isozyme II and IX (507 views)
J Am Chem Soc (ISSN: 0002-7863, 0002-2786, 1520-5126), 2006 Jun 28; 128(25): 8329-8335.
Impact Factor: 7.696
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Galdiero S, Vitiello M, Amodeo P, D'Isanto M, Cantisani M, Pedone C, Galdiero M
* Structural requirements for proinflammatory activity of porin P2 loop 7 from Haemophilus influenzae (575 views)
Biochemistry (ISSN: 0006-2960, 1520-4995, 1520-4995electronic), 2006 Apr 11; 45(14): 4491-4501.
Impact Factor: 3.633
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Cappiello M, Alterio V, Amodeo P, Del Corso A, Scaloni A, Pedone C, Moschini R, De Donatis GM, De Simone G, Mura U
* A new spot test for sulfhydryl-containing compounds (454 views)
Anal Biochem, 2006 Mar 14; 79(1-2): 610-611.
Impact Factor: 2.305
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Cappiello M, Alterio V, Amodeo P, Del Corso A, Scaloni A, Pedone C, Moschini R, De Donatis GM, De Simone G, Mura U
* Metal ion substitution in the catalytic site greatly affects the binding of sulfhydryl-containing compounds to leucyl aminopeptidase (769 views)
Biochemistry (ISSN: 0006-2960, 1520-4995, 1520-4995electronic), 2006 Mar 14; 45(10): 3226-3234.
Impact Factor: 3.633
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Arena G, Casnati A, Contino A, Magrì A, Sansone F, Sciotto D, Ungaro R
* Inclusion of naturally occurring amino acids in water soluble calix[4]arenes: A microcalorimetric and 1H NMR investigation supported by molecular modeling (390 views)
Org Biomol Chem (ISSN: 1477-0520, 1477-0539, 1477-0539electronic), 2006 Jan 21; 4(2): 243-249.
Impact Factor: 2.874
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De Luca S, Della Moglie R, De Capua A, Morelli G
* New synthetic strategy for o-NBS protected amino acids and their use in synthesis of mono-benzylated peptides (455 views)
Tetrahedron Lett (ISSN: 0040-4039), 2005 Sep 26; 46(39): 6637-6640.
Impact Factor: 2.477
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Improta R, Antonello S, Formaggio F, Maran F, Rega N, Barone V
* Understanding Electron Transfer across Negatively-Charged Aib Oligopeptides (648 views)
J Phys Chem B (ISSN: 1520-6106, 1520-5207, 1520-5207electronic), 2005 Jan 20; 109(2): 1023-1033.
Impact Factor: 4.033
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Falcigno L, Oliva R, D'Auria G, Maletta M, Dettin M, Pasquato A, Di Bello C, Paolillo L
* Structural investigation of the HIV-1 envelope glycoprotein gp160 cleavage site 3: Role of site-specific mutations (437 views)
Chembiochem (ISSN: 1439-4227, 1439-7633, 1439-7633electronic), 2004 Dec 3; 5(12): 1653-1661.
Impact Factor: 3.474
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Merlino A, Graziano G, Mazzarella L
* Structural And Dynamic Effects Of Alpha-Helix Deletion In Sso7d: Implications For Protein Thermal Stability (423 views)
Proteins (ISSN: 0887-3585, 1097-0134, 1097-0134electronic), 2004 Dec 1; 57(4): 692-701.
Impact Factor: 4.429
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Cucinotta V, Giuffrida A, La Mendola D, Maccarrone G, Puglisi A, Rizzarelli E, Vecchio G
* 3-Amino Derivative Of Beta-Cyclodextrin: Thermodynamics Of Copper (ii) Complexes And Exploitation Of Its Enantioselectivity In The Separation Of Amino Acid Racemates By Ligand Exchange Capillary Electrophoresis (350 views)
And Life Sciencesjournal Of Chromatography B Analytical Technologies In The Biomedical, 2004 Feb 5; 800(1-2): 127-133.
Impact Factor: 1.403
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Rossi F, Zanotti G, Saviano M, Iacovino R, Palladino P, Saviano G, Amodeo P, Tancredi T, Laccetti P, Corbier C, Benedetti E
* New antitumour cyclic astin analogues: Synthesis, conformation and bioactivity (454 views)
J Pept Sci (ISSN: 1075-2617, 1099-1387, 1075-2617print), 2004 Feb; 10(2): 92-102.
Impact Factor: 1.652
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Zarivach R, Bashan A, Berisio R, Harms J, Auerbach T, Schluenzen F, Bartels H, Baram D, Pyetan E, Sittner A, Amit M, Hansen HAS, Kessler M, Liebe C, Wolff A, Agmon I, Yonath A
* Functional aspects of ribosomal architecture: Symmetry, chirality and regulation (504 views)
J Phys Org Chem (ISSN: 0894-3230), 2004; 17(11): 901-912.
Impact Factor: 1.211
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Isernia C, Bucci E, Leone M, Zaccaro L, Di Lello P, Digilio G, Esposito S, Saviano M, Di Blasio B, Pedone C, Pedone PV, Fattorusso R
* NMR structure of the single QALGGH zinc finger domain from the Arabidopsis thaliana SUPERMAN protein (430 views)
Chembiochem (ISSN: 1439-4227, 1439-7633, 1439-7633electronic), 2003 Mar 3; 4(2-3): 171-180.
Impact Factor: 3.992
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Formaggio F, Crisma M, Toniolo C, Broxterman QB, Kaptein B, Corbier C, Saviano M, Palladino P, Benedetti E
* Cα-Methyl, Cα-n-Propylglycine Homo-oligomers (321 views)
Macromolecules (ISSN: 0024-9297), 2003; 36(21): 8164-8170.
Impact Factor: 3.621
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D'Amore M, Improta R, Barone V
* Conformational behavior and magnetic properties of a nitroxide amino acid derivative in vacuo and in aqueous solution (238 views)
J Phys Chem A (ISSN: 1089-5639, 1520-5215electronic), 2003; 107(32): 6264-6269.
Impact Factor: 2.792
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Peggion C, Formaggio F, Crisma M, Toniolo C, Jimenez AI, Cativiela C, Kaptein B, Broxterman QB, Saviano M, Benedetti E
* Folding of peptides characterized by c3Val, a highly constrained analogue of valine (429 views)
Biopolymers (ISSN: 0006-3525, 0006-6352, 0006-3525print), 2003; 68(2): 178-191.
Impact Factor: 2.733
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Formaggio F, Bonchio M, Crisma M, Peggion C, Mezzato S, Polese A, Barazza A, Antonello S, Maran F, Broxterman QB, Kaptein B, Kamphuis J, Vitale RM, Saviano M, Benedetti E, Toniolo C
* Nitroxyl peptides as catalysts of enantioselective oxidations (498 views)
Chemistry (ISSN: 0947-6539, 1521-3765, 1521-3765electronic), 2002; 8(1): [d]84-93.
Impact Factor: 4.238
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De Falco S, Ruvoletto MG, Verdoliva A, Ruvo M, Raucci A, Marino M, Senatore S, Cassani G, Alberti A, Pontisso P, Fassina G
* Cloning and Expression of a Novel Hepatitis B Virus-binding Protein from HepG2 Cells (628 views)
Jbc Papers (ISSN: 0021-9258, 1083-351x, 0021-9258linking), 2001 Sep 28; 276(39): 36613-36623.
Impact Factor: 7.258
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Romanelli A, Garella I, Menchise V, Iacovino R, Saviano M, Montesarchio D, Didierjean C, Lello PD, Rossi F, Benedetti E
* Crystal-state conformation of Cα, α-dialkylated peptides containing chiral β-homo-residues (519 views)
J Pept Sci (ISSN: 1075-2617, 1099-1387, 1075-2617print), 2001; 7(1): 15-26.
Impact Factor: 1.451
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Pavone V, Lombardi A, Saviano M, De Simone G, Nastri F, Maglio O, Omote Y, Yamanaka Y, Yamada T
Conformational behavior of C(α, α)-diphenyl glycine: Extended conformation in tripeptides containing consecutive Dφg residues (408 views)
Biopolymers (ISSN: 0006-3525, 0006-6352, 0006-3525print), 2000 Feb; 53(2): 161-168.
Impact Factor: 2.405
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De Simone G, Lombardi A, Galdiero S, Nastri F, Di Costanzo L, Gohda S, Sano A, Yamada T, Pavone V
The crystal structure of a Dcp-containing peptide (456 views)
Biopolymers (ISSN: 0006-3525, 0006-6352, 0006-3525print), 2000 Feb; 53(2): 182-188.
Impact Factor: 2.405
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Lombardi A, De Simone G, Galdiero S, Nastri F, Di Costanzo L, Makihiara K, Yamada T, Pavone V
The crystal structure of Afc-containing peptide (473 views)
Biopolymers (ISSN: 0006-3525, 0006-6352, 0006-3525print), 2000 Feb; 53(2): 150-160.
Impact Factor: 2.405
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Caliendo G, Fiorino F, Grieco P, Perissutti E, De Luca S, Giuliano A, Santelli G, Califano D, Severino B, Santagada V
Synthesis and biological activity of pseudopeptides inhibitors of Ras farnesyl transferase containing unconventional amino acids (549 views)
Farmaco (ISSN: 0014-827x), 1999 Nov; 54(11-12): 785-790.
Impact Factor: 0.406
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Pavone V, Lombardi A, Saviano M, Nastri F, Zaccaro L, Maglio O, Pedone C, Omote Y, Yamanaka Y, Yamada T
Conformational Behaviour Of C (alpha, Alpha)-Diphenylglycine: Folded Vs. Extended Structures In Dphig-Containing Tripeptides (454 views)
J Pept Sci (ISSN: 1075-2617, 1099-1387, 1075-2617print), 1998 Feb; 4(1): 21-32.
Impact Factor: 1.311
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Campagna T, Grasso G, Rizzarelli E, Vecchio G
L- and D-cysteine derivatives of β-cyclodextrin: Different molecular recognition properties of their copper(II) complexes for amino acids (363 views)
Inorg Chim Acta (ISSN: 0020-1693), 1998; 275-276: 395-400.
Impact Factor: 1.454
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Benedetti E, Iacovino R, Pedone C, Rossi F, Saviano M, Isernia C, Montesarchio D, DeNapoli L, Piccialli G
β-Amino acid residues: Conformational characterization of an N- and C-protected homo-β-(S)-leucine (314 views)
Int J Pept Res Ther (ISSN: 0929-5666, 1573-3149), 1997 Jun; 4(3): 129-134.
Impact Factor: 0.557
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Bonomo RP, Cucinotta V, D'Alessandro F, Impellizzeri G, Maccarrone G, Rizzarelli E, Vecchio G, Carima L, Corradini R, Sartor G, Marchelli R
Chiral recognition by the copper(ii) complex of 6-deoxy-6-n-(2 - methylaminopyridine)-β-cyclodextrin (381 views)
Chirality (ISSN: 0899-0042), 1997; 9(4): 341-349.
Impact Factor: 1.915
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Crisma M, Formaggio F, Valle G, Toniolo C, Saviano M, Iacovino R, Zaccaro L, Benedetti E
Experimental evidence at atomic resolution for intramolecular N- H···π (phenyl) interactions in a family of amino acid derivatives (418 views)
Biopolymers (ISSN: 0006-3525, 0006-6352, 0006-3525print), 1997; 42(1): 1-6.
Impact Factor: 2.425
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Bonomo RP, Pedotti S, Vecchio G, Rizzarelli E
Molecular Recognition of Amino Acids by Copper(II) Complexes of 6A, 6X-Diamino-6A, 6 X-dideoxy-β-cyclodextrin (X = B, C, D) (254 views)
Inorg Chem (ISSN: 0020-1669, 1520-510x, 1520-510xelectronic), 1996 Nov 6; 35(23): 6873-6877.
Impact Factor: 2.736
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Lombardi A, D'Auria G, Saviano M, Maglio O, Nastri F, Quartara L, Pedone C, Pavone V
Bicyclic Peptides As Type I/Type Ii Beta-Turn Scaffolds (514 views)
Biopolym Pept Sci Sect, 1996; 40(5): 505-518.
Impact Factor: 0
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Rossi F, Saviano M, Di Talia P, Di Blasio B, Pedone C, Zanotti G, Mosca M, Saviano G, Tancredi T, Ziegler K, Benedetti E
Solution and solid state structure of an aib-containing cyclodecapeptide inhibiting the cholate uptake in hepatocytes (455 views)
Biopolymers (ISSN: 0006-3525, 0006-6352, 0006-3525print), 1996; 40(5): 465-478.
Impact Factor: 2.425
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Pavone V, Lombardi A, Saviano M, Di Blasio B, Nastri F, Fattorusso R, Zaccaro L, Maglio O, Yamada T, Omote Y
Mixed conformation in C(α, α)-disubstituted tripeptides: X-ray crystal structures of Z-Aib-Dph-Gly-OMe and Bz-Dph-Dph-Gly-OMe (401 views)
Biopolymers (ISSN: 0006-3525, 0006-6352, 0006-3525print), 1994 Dec; 34(12): 1595-1604.
Impact Factor: 2.425
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Zanotti G, Maione A, Rossi F, Saviano M, Pedone C, Tancredi T
BIOACTIVE PEPTIDES - CONFORMATIONAL STUDY OF A CYSTINYL CYCLOHEPTAPEPTIDE IN ITS FREE AND CALCIUM COMPLEXED FORMS (581 views)
Biopolymers (ISSN: 0006-3525, 0006-6352, 0006-3525print), 1993 Jul; 33(7): 1083-1091.
Impact Factor: 2.425
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Arena G, Bindoni M, Cardile V, Maccarrone G, Riello MC, Rizzarelli E, Sciuto S
Cytotoxic and cytostatic activity of copper(II) complexes. Importance of the speciation for the correct interpretation of the in vitro biological results (478 views)
J Chem Res (ISSN: 0162-0134, 1873-3344, 0162-0134print), 1993 Apr 1; 50(1): 31-45.
Impact Factor: 1.342
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Pavone V, Di Blasio B, Lombardi A, Maglio O, Isernia C, Pedone C, Benedetti E, Altmann E, Mutter M
Non coded C alpha, alpha-disubstituted amino acids. X-ray diffraction analysis of a dipeptide containing (S)-alpha-methylserine (370 views)
Int J Pept Protein Res (ISSN: 0367-8377, 0367-8377print, 0367-8377linking), 1993 Jan; 41(1): 15-20.
Impact Factor: 1.255
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Lombardi A, Maglio O, Pavone B, Di Blasio V, Saviano M, Nastri F, Pedone C, Benedetti E
Pt(II) Complexes of Amino Acids and Peptides. III. X-Ray Diffraction Study of trans-[Cl-(Ph3P)-Pt-(H-Aib-O-)] (414 views)
Inorg Chim Acta, 1993; 204: 87-92.
Impact Factor: 0
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Lombardi A, Maglio O, Benedetti B, Di Blasio E, Saviano M, Nastri F, Pedone C, Pavone V
Pt(II) Complexes of Amino Acids and Peptides. II. Structural Analysis of trans-[Cl2-Pt-(H-Aib-OH)2] (429 views)
Inorg Chim Acta, 1992; 196: 241-246.
Impact Factor: 0
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Della Ragione F, Oliva A, Gragnaniello V, Russo GL, Palumbo R, Zappia V
Physicochemical and immunological studies on mammalian 5'-deoxy-5'-methylthioadenosine phosphorylase (26 views) (PDF 8 views)
J Biol Chem (ISSN: 0021-9258linking), 1990 Apr 15; 265(11): 6241-6246.
Impact Factor: 5.328
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Alberghina M, Brogna A, Mangiameli A, Marletta F, Rizzarelli E, Sammartano S
Copper(II) complexes of aminoacids: Gastric acid antisecretory activity in rats (2114 views)
Farmaco Ed Sci, 1982 Dec; 37(12): 805-814.
Impact Factor: 0
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97 Records (96 excluding Abstracts).
Total impact factor: 336.287 (333.404 excluding Abstracts).
Total 5 year impact factor: 342.047 (339.338 excluding Abstracts).
Total impact factor: 336.287 (333.404 excluding Abstracts).
Total 5 year impact factor: 342.047 (339.338 excluding Abstracts).
804 views. Last view on Tuesday 06 June 2023, 18:46:36
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