Mild cognitive impairment in drug-naive patients with PD is associated with cerebral hypometabolism(491 views) Pappata S, Santangelo G, Aarsland D, Vicidomini C, Longo K, Bronnick K, Amboni M, Erro R, Vitale C, Caprio MG, Pellecchia MT, Brunetti A, De Michele G, Salvatore M, Barone P
Neurology (ISSN: 0028-3878, 1526-632x, 1526-632xelectronic), 2011 Oct 4; 77(14): 1357-1362.
Institute of Biostructure and Bioimaging, CNR, Via Pansini 5, Edificio 10, 80131, Naples, Italy
Department of Psychology, Second University of Naples, Caserta, Italy
IDC Hermitage Capodimonte, Naples, Italy
Departments of Neurological Sciences, University Federico II, Naples, Italy
Departments of Biomorphological Sciences, University Federico II, Naples, Italy
Psychiatric Division (D.A., K.B.), Stavanger University Hospital, University of Oslo, Oslo, Norway
University Parthenope, Naples, Italy
Centro Regionale, Schola Medica Salernitana, University of Salerno, Italy
References: Williams-Gray, C.H., Foltynie, T., Brayne, C.E.G., Robbins, T.W., Barker, R.A., Evolution of cognitive dysfunction in an incident Parkinson's disease cohort (2007) Brain, 130 (7), pp. 1787-1798. , DOI 10.1093/brain/awm11
Muslimovic, D., Post, B., Speelman, J.D., Schmand, B., Cognitive profile of patients with newly diagnosed Parkinson disease (2005) Neurology, 65 (8), pp. 1239-1245. , DOI 10.1212/01.wnl.0000180516.69442.95
Aarsland, D., Brønnick, K., Larsen, J.P., Cognitive impairment in incident, untreated Parkinson disease: The Norwegian ParkWest study (2009) Neurology, 72, pp. 1121-1126
Janvin, C.C., Larsen, J.P., Aarsland, D., Hugdahl, K., Subtypes of mild cognitive impairment in Parkinson's disease: Progression to dementia (2006) Movement Disorders, 21 (9), pp. 1343-1349. , DOI 10.1002/mds.20974
Huang, C., Mattis, P., Perrine, K., Brown, N., Dhawan, V., Eidelberg, D., Metabolic abnormalities associated with mild cognitive impairment in Parkinson disease (2008) Neurology, 70 (16 PART 2), pp. 1470-1477. , DOI 10.1212/01.wnl.0000304050.05332.9c, PII 0000611420080415100017
Hosokai, Y., Nishio, Y., Hirayama, K., Distinct patterns of regional cerebral glucose metabolism in Parkinson's disease with and without mild cognitive impairment (2009) Mov Disord, 24, pp. 854-862
Borghammer, P., Chakravarty, M., Jonsdottir, K.Y., Cortical hypometabolism and hypoperfusion in Parkinson's disease is extensive: Probably even at early disease stages Brain Struct Funct, 2010 (214), pp. 303-317
Berding, G., Odin, P., Brooks, D.J., Nikkhah, G., Matthies, C., Peschel, T., Shing, M., Knapp, W.H., Resting regional cerebral glucose metabolism in advanced Parkinson's disease studied in the off and on conditions with [18F]FDG-PET (2001) Movement Disorders, 16 (6), pp. 1014-1022. , DOI 10.1002/mds.1212
Feigin, A., Fukuda, M., Dhawan, V., Przedborski, S., Jackson-Lewis, V., Mentis, M.J., Moeller, J.R., Eidelberg, D., Metabolic correlates of levodopa response in Parkinson's disease (2001) Neurology, 57 (11), pp. 2083-2088
Hirano, S., Asanuma, K., Ma, Y., Dissociation of metabolic and neurovascular responses to levodopa in the treatment of Parkinson's disease (2008) J Neurosci, 28, pp. 4201-4209
Hughes, A.J., Daniel, S.E., Kilford, L., Lees, A.J., Accuracy of clinical diagnosis of idiopathic Parkinson's Disease: A clinic-pathological study of 100 cases (1992) J Neurol Neurosurg Psychiatry, 55, pp. 181-184
Emre, M., Aarsland, D., Brown, R., Burn, D.J., Duyckaerts, C., Mizuno, Y., Broe, G.A., Dubois, B., Clinical diagnostic criteria for dementia associated with Parkinson's disease (2007) Movement Disorders, 22 (12), pp. 1689-1707. , DOI 10.1002/mds.21507
Aarsland, D., Bronnick, K., Williams-Gray, C., Mild cognitive impairment in Parkinson disease: A multicenter pooled analysis Neurology, 2010 (75), pp. 1062-1069
Pappatà, S., Varrone, A., Vicidomini, C., SPECT imaging of GABA(A)/benzodiazepine receptors and cerebral perfusion in mild cognitive impairment (2010) Eur J Nucl Med Mol Imaging, 37, pp. 1156-1163
Borghammer, P., Cumming, P., Aanerud, J., Gjedde, A., Artefactual subcortical hyperperfusion in PET studies normalized to global mean: Lessons from Parkinson's disease (2009) Neuroimage, 45, pp. 249-257
Nobili, F., Abbruzzese, G., Morbelli, S., Amnestic mild cognitive impairment in Parkinson's disease: A brain perfusion SPECT study (2009) Mov Disord, 24, pp. 414-421
Huang, C., Tang, C., Feigin, A., Lesser, M., Ma, Y., Pourfar, M., Dhawan, V., Eidelberg, D., Changes in network activity with the progression of Parkinson's disease (2007) Brain, 130 (7), pp. 1834-1846. , DOI 10.1093/brain/awm086
Klein, J.C., Eggers, C., Kalbe, E., Neurotransmitter changes in dementia with Lewy bodies and Parkinson disease dementia in vivo Neurology, 2010 (74), pp. 885-892
Berti, V., Polito, C., Ramat, S., Brain metabolic correlates of dopaminergic degeneration in de novo idiopathic Parkinson's disease (2010) Eur J Nucl Med Mol Imaging, 37, pp. 537-544
Polito, C., Berti, V., Ramat, S., Interaction of caudate dopamine depletion and brain metabolic changes with cognitive dysfunction in early Parkinson's disease (2010) Neurobiol Aging Epub
Shimada, H., Hirano, S., Shinotoh, H., Mapping of brain acetylcholinesterase alterations in Lewy body disease by PET (2009) Neurology, 73, pp. 273-278
Ferrer, I., Martinez, A., Blanco, R., Dalfó, E., Carmona, M., Neuropathology of sporadic Parkinson disease before the appearance of parkinsonism: Preclinical Parkinson disease (2011) J Neural Transm, 118, pp. 821-839
Braak, H., Del Tredici, K., Rub, U., De Vos, R.A.I., Jansen Steur, E.N.H., Braak, E., Staging of brain pathology related to sporadic Parkinson's disease (2003) Neurobiology of Aging, 24 (2), pp. 197-211. , DOI 10.1016/S0197-4580(02)00065-9, PII S0197458002000659
Apostolova, L.G., Beyer, M., Green, A.E., Hippocampal, caudate, and ventricular changes in Parkinson's disease with and without dementia Mov Disord, 2010 (25), pp. 687-688
Van Laere, K., Santens, P., Bosman, T., De Reuck, J., Mortelmans, L., Dierckx, R., Statistical parametric mapping of 99mTc-ECD SPECT in idiopathic Parkinson's disease and multiple system atrophy with predominant parkinsonian features: Correlation with clinical parameters (2004) Journal of Nuclear Medicine, 45 (6), pp. 933-942. , http://jnm.snmjournals.org/cgi/reprint/45/6/933
Williams-Gray, C. H., Foltynie, T., Brayne, C. E. G., Robbins, T. W., Barker, R. A., Evolution of cognitive dysfunction in an incident Parkinson's disease cohort (2007) Brain, 130 (7), pp. 1787-1798. , DOI 10. 1093/brain/awm11
Aarsland, D., Br nnick, K., Larsen, J. P., Cognitive impairment in incident, untreated Parkinson disease: The Norwegian ParkWest study (2009) Neurology, 72, pp. 1121-1126
Janvin, C. C., Larsen, J. P., Aarsland, D., Hugdahl, K., Subtypes of mild cognitive impairment in Parkinson's disease: Progression to dementia (2006) Movement Disorders, 21 (9), pp. 1343-1349. , DOI 10. 1002/mds. 20974
Hughes, A. J., Daniel, S. E., Kilford, L., Lees, A. J., Accuracy of clinical diagnosis of idiopathic Parkinson's Disease: A clinic-pathological study of 100 cases (1992) J Neurol Neurosurg Psychiatry, 55, pp. 181-184
Pappat, S., Varrone, A., Vicidomini, C., SPECT imaging of GABA (A) /benzodiazepine receptors and cerebral perfusion in mild cognitive impairment (2010) Eur J Nucl Med Mol Imaging, 37, pp. 1156-1163
Klein, J. C., Eggers, C., Kalbe, E., Neurotransmitter changes in dementia with Lewy bodies and Parkinson disease dementia in vivo Neurology, 2010 (74), pp. 885-892
Apostolova, L. G., Beyer, M., Green, A. E., Hippocampal, caudate, and ventricular changes in Parkinson's disease with and without dementia Mov Disord, 2010 (25), pp. 687-688
Mild cognitive impairment in drug-naive patients with PD is associated with cerebral hypometabolism
Bruni AC, Bernardi L, Colao R, Rubino E, Smirne N, Frangipane F, Terni B, Curcio SA, Mirabelli M, Clodomiro A, Di Lorenzo R, Maletta R, Anfossi M, Gallo M, Geracitano S, Tomaino C, Muraca MG, Leotta A, Lio SG, Pinessi L, Rainero I, Sorbi S, Nee L, Milan G, Pappata S, Postiglione A, Abbamondi N, Forloni G, St George Hyslop P, Rogaeva E, Bugiani O, Giaccone G, Foncin JF, Spillantini MG, Puccio G * Worldwide distribution of PSEN1 Met146Leu mutation: A large variability for a founder mutation(972 views) Neurology (ISSN: 0028-3878, 1526-632x, 1526-632xelectronic), 2010 Mar 9; 74(10): 798-806. Impact Factor:8.017 ViewExport to BibTeXExport to EndNote