Multivariate normal tissue complication probability modeling of heart valve dysfunction in Hodgkin lymphoma survivors (456 views)
Int J Radiat Oncol (ISSN: 0360-3016, 1879-355x, 1879-355xelectronic), 2013 Oct 1; 87(2): 304-310.
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Paper type: Journal Article, Research Support, Non-U. S. Gov'T,
Impact factor: 4.176, 5-year impact factor: 4.441
Url: http://www.scopus.com/inward/record.url?eid=2-s2.0-84882862158&partnerID=40&md5=e9f427e1b6f183eaa27b85c16ee193bc
Keywords: Chemoradiation Therapies, Clinical Information, Methods And Materials, Multivariate Logistic Regressions, Receiver Operating Characteristic Curves, Resampling Technique, Spearman, S Rank Correlation Coefficients, Statistical Evidence, Biological Organs, Oncology, Patient Monitoring, Regression Analysis, Tissue, Heart, Adolescent, Adult, Aged, Article, Cancer Survivor, Chemoradiotherapy, Dosimetry, Female, Heart Left Atrium, Heart Left Ventricle, Heart Right Atrium, Heart Right Ventricle, Heart Volume, Hodgkin Disease, Human, Lung Volume, Major Clinical Study, Normal Tissue Complication Probability, Predictive Value, Priority Journal, Radiation Dose, Radiation Dose Distribution, Radiation Injury, Retrospective Study, Simulation, Valvular Heart Disease, Antineoplastic Combined Chemotherapy Protocols, Area Under Curve, Heart Valve Diseases, Middle Aged, Models, Multivariate Analysis, Organ Size, Radiation Injuries, Retrospective Studies, Young Adult,
Affiliations:
*** IBB - CNR ***
Institute of Biostructures and Bioimaging, National Council of Research, Naples, Italy. laura.cella@cnr.it
Department of Advanced Biomedical Sciences, Federico II University School of Medicine, Naples, Italy
References:
Not available.
Int J Radiat Oncol (ISSN: 0360-3016, 1879-355x, 1879-355xelectronic), 2013 Oct 1; 87(2): 304-310.
Export to BibTeX Export to EndNote
Paper type: Journal Article, Research Support, Non-U. S. Gov'T,
Impact factor: 4.176, 5-year impact factor: 4.441
Url: http://www.scopus.com/inward/record.url?eid=2-s2.0-84882862158&partnerID=40&md5=e9f427e1b6f183eaa27b85c16ee193bc
Keywords: Chemoradiation Therapies, Clinical Information, Methods And Materials, Multivariate Logistic Regressions, Receiver Operating Characteristic Curves, Resampling Technique, Spearman, S Rank Correlation Coefficients, Statistical Evidence, Biological Organs, Oncology, Patient Monitoring, Regression Analysis, Tissue, Heart, Adolescent, Adult, Aged, Article, Cancer Survivor, Chemoradiotherapy, Dosimetry, Female, Heart Left Atrium, Heart Left Ventricle, Heart Right Atrium, Heart Right Ventricle, Heart Volume, Hodgkin Disease, Human, Lung Volume, Major Clinical Study, Normal Tissue Complication Probability, Predictive Value, Priority Journal, Radiation Dose, Radiation Dose Distribution, Radiation Injury, Retrospective Study, Simulation, Valvular Heart Disease, Antineoplastic Combined Chemotherapy Protocols, Area Under Curve, Heart Valve Diseases, Middle Aged, Models, Multivariate Analysis, Organ Size, Radiation Injuries, Retrospective Studies, Young Adult,
Affiliations:
*** IBB - CNR ***
Institute of Biostructures and Bioimaging, National Council of Research, Naples, Italy. laura.cella@cnr.it
Department of Advanced Biomedical Sciences, Federico II University School of Medicine, Naples, Italy
References:
Not available.
Multivariate normal tissue complication probability modeling of heart valve dysfunction in Hodgkin lymphoma survivors
Purpose To establish a multivariate normal tissue complication probability (NTCP) model for radiation-induced asymptomatic heart valvular defects (RVD). Methods and Materials Fifty-six patients treated with sequential chemoradiation therapy for Hodgkin lymphoma (HL) were retrospectively reviewed for RVD events. Clinical information along with whole heart, cardiac chambers, and lung dose distribution parameters was collected, and the correlations to RVD were analyzed by means of Spearman's rank correlation coefficient (Rs). For the selection of the model order and parameters for NTCP modeling, a multivariate logistic regression method using resampling techniques (bootstrapping) was applied. Model performance was evaluated using the area under the receiver operating characteristic curve (AUC). Results When we analyzed the whole heart, a 3-variable NTCP model including the maximum dose, whole heart volume, and lung volume was shown to be the optimal predictive model for RVD (Rs = 0.573, P
Purpose To establish a multivariate normal tissue complication probability (NTCP) model for radiation-induced asymptomatic heart valvular defects (RVD). Methods and Materials Fifty-six patients treated with sequential chemoradiation therapy for Hodgkin lymphoma (HL) were retrospectively reviewed for RVD events. Clinical information along with whole heart, cardiac chambers, and lung dose distribution parameters was collected, and the correlations to RVD were analyzed by means of Spearman's rank correlation coefficient (Rs). For the selection of the model order and parameters for NTCP modeling, a multivariate logistic regression method using resampling techniques (bootstrapping) was applied. Model performance was evaluated using the area under the receiver operating characteristic curve (AUC). Results When we analyzed the whole heart, a 3-variable NTCP model including the maximum dose, whole heart volume, and lung volume was shown to be the optimal predictive model for RVD (Rs = 0.573, P
Multivariate normal tissue complication probability modeling of heart valve dysfunction in Hodgkin lymphoma survivors
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Multivariate normal tissue complication probability modeling of heart valve dysfunction in Hodgkin lymphoma survivors
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Di Lascio N, Avigo C, Salvati A, Martini N, Ragucci M, Monti S, Prinster A, Chiappino D, Mancini M, D'Elia D, Ghiadoni L, Bonino F, Brunetto MR, Faita F
* Steato-Score: Non-Invasive Quantitative Assessment of Liver Fat by Ultrasound Imaging (492 views)
Ultrasound Med Biol (ISSN: 0301-5629, 0301-5629linking), 2018; 44(8): 1585-1596.
Impact Factor: 2.494
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Cella L, Conson M, Caterino M, De Rosa N, Liuzzi R, Picardi M, Grimaldi F, Solla R, Farella A, Salvatore M, Pacelli R
* Thyroid V30 predicts radiation-induced hypothyroidism in patients treated with sequential chemo-radiotherapy for Hodgkin's lymphoma (523 views) (PDF 240 views)
Int J Radiat Oncol (ISSN: 0360-3016, 1879-355x, 1879-355xelectronic), 2012 Apr 1; 82(5): 1802-1808.
Impact Factor: 4.524
View Export to BibTeX Export to EndNote
* Steato-Score: Non-Invasive Quantitative Assessment of Liver Fat by Ultrasound Imaging (492 views)
Ultrasound Med Biol (ISSN: 0301-5629, 0301-5629linking), 2018; 44(8): 1585-1596.
Impact Factor: 2.494
View Export to BibTeX Export to EndNote
Cella L, Conson M, Caterino M, De Rosa N, Liuzzi R, Picardi M, Grimaldi F, Solla R, Farella A, Salvatore M, Pacelli R
* Thyroid V30 predicts radiation-induced hypothyroidism in patients treated with sequential chemo-radiotherapy for Hodgkin's lymphoma (523 views) (PDF 240 views)
Int J Radiat Oncol (ISSN: 0360-3016, 1879-355x, 1879-355xelectronic), 2012 Apr 1; 82(5): 1802-1808.
Impact Factor: 4.524
View Export to BibTeX Export to EndNote
2 Records (2 excluding Abstracts).
Total impact factor: 7.018 (7.018 excluding Abstracts).
Total 5 year impact factor: 7.332 (7.332 excluding Abstracts).
Total impact factor: 7.018 (7.018 excluding Abstracts).
Total 5 year impact factor: 7.332 (7.332 excluding Abstracts).
456 views. Last view on Friday 17 November 2023, 23:31:27
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