Multivariate normal tissue complication probability modeling of heart valve dysfunction in Hodgkin lymphoma survivors (390 views)
Int J Radiat Oncol (ISSN: 0360-3016, 1879-355x, 1879-355xelectronic), 2013 Oct 1; 87(2): 304-310.
Export to BibTeX Export to EndNote
Paper type: Journal Article, Research Support, Non-U. S. Gov'T,
Impact factor: 4.176, 5-year impact factor: 4.441
Url: http://www.scopus.com/inward/record.url?eid=2-s2.0-84882862158&partnerID=40&md5=e9f427e1b6f183eaa27b85c16ee193bc
Keywords: Chemoradiation Therapies, Clinical Information, Methods And Materials, Multivariate Logistic Regressions, Receiver Operating Characteristic Curves, Resampling Technique, Spearman, S Rank Correlation Coefficients, Statistical Evidence, Biological Organs, Oncology, Patient Monitoring, Regression Analysis, Tissue, Heart, Adolescent, Adult, Aged, Article, Cancer Survivor, Chemoradiotherapy, Dosimetry, Female, Heart Left Atrium, Heart Left Ventricle, Heart Right Atrium, Heart Right Ventricle, Heart Volume, Hodgkin Disease, Human, Lung Volume, Major Clinical Study, Normal Tissue Complication Probability, Predictive Value, Priority Journal, Radiation Dose, Radiation Dose Distribution, Radiation Injury, Retrospective Study, Simulation, Valvular Heart Disease, Antineoplastic Combined Chemotherapy Protocols, Area Under Curve, Heart Valve Diseases, Middle Aged, Models, Multivariate Analysis, Organ Size, Radiation Injuries, Retrospective Studies, Young Adult,
Affiliations:
*** IBB - CNR ***
Institute of Biostructures and Bioimaging, National Council of Research, Naples, Italy. laura.cella@cnr.it
Department of Advanced Biomedical Sciences, Federico II University School of Medicine, Naples, Italy
References:
Darby, S.C., Cutter, D.J., Boerma, M., Radiation-related heart disease: Current knowledge and future prospects (2010) Int J Radiat Oncol Biol Phys, 76, pp. 656-66
Gagliardi, G., Constine, L.S., Moiseenko, V., Radiation dose-volume effects in the heart (2010) Int J Radiat Oncol Biol Phys, 76 (3 SUPPL.), pp. 77-S85
Cella, L., Conson, M., Caterino, M., Thyroid V30 predicts radiation-induced hypothyroidism in patients treated with sequential chemo-radiotherapy for Hodgkin's lymphoma (2012) Int J Radiat Oncol Biol Phys, 82, pp. 1802-1808
Engert, A., Plutschow, A., Eich, H.T., Reduced treatment intensity in patients with early-stage Hodgkin's lymphoma (2010) N Engl J Med, 363, pp. 640-652
Cella, L., Liuzzi, R., Conson, M., Dosimetric predictors of asymptomatic heart valvular dysfunction following mediastinal irradiation for Hodgkin's lymphoma (2011) Radiother Oncol, 101, pp. 316-321
Heidenreich, P.A., Hancock, S.L., Lee, B.K., Asymptomatic cardiac disease following mediastinal irradiation (2003) J Am Coll Cardiol, 42, pp. 743-749
Wethal, T., Lund, M.B., Edvardsen, T., Valvular dysfunction and left ventricular changes in Hodgkin's lymphoma survivors: A longitudinal study (2009) Br J Cancer, 101, pp. 575-581
Adams, M.J., Hardenbergh, P.H., Constine, L.S., Radiation-associated cardiovascular disease (2003) Crit Rev Oncol Hematol, 45, pp. 55-75
Ghobadi, G., Van Der Veen, S., Bartelds, B., Physiological interaction of heart and lung in thoracic irradiation (2012) Int J Radiat Oncol Biol Phys, 84, pp. 639-e646
Huang, E.X., Hope, A.J., Lindsay, P.E., Heart irradiation as a risk factor for radiation pneumonitis (2011) Acta Oncol, 50, pp. 51-60
El Naqa, I., Bradley, J., Blanco, A.I., Multivariable modeling of radiotherapy outcomes, including dose-volume and clinical factors (2006) Int J Radiat Oncol Biol Phys, 64, pp. 1275-1286
Feng, M., Moran, J.M., Koelling, T., Development and validation of a heart atlas to study cardiac exposure to radiation following treatment for breast cancer (2011) Int J Radiat Oncol Biol Phys, 79, pp. 10-18
El Naqa, I., Suneja, G., Lindsay, P.E., Dose response explorer: An integrated open-source tool for exploring and modelling radiotherapy dose-volume outcome relationships (2006) Phys Med Biol, 51, pp. 5719-5735
Trott, K.R., Doerr, W., Facoetti, A., Biological mechanisms of normal tissue damage: Importance for the design of NTCP models (2012) Radiother Oncol, 105, pp. 79-85
Van Der Schaaf, A., Xu, C.J., Van Luijk, P., Multivariate modeling of complications with data driven variable selection: Guarding against overfitting and effects of data set size (2012) Radiother Oncol, 105, pp. 115-121
Defraene, G., Van Den Bergh, L., Al-Mamgani, A., The benefits of including clinical factors in rectal normal tissue complication probability modeling after radiotherapy for prostate cancer (2012) Int J Radiat Oncol Biol Phys, 82, pp. 1233-1242
Van Luijk, P., Faber, H., Meertens, H., The impact of heart irradiation on dose-volume effects in the rat lung (2007) Int J Radiat Oncol Biol Phys, 69, pp. 552-559
Int J Radiat Oncol (ISSN: 0360-3016, 1879-355x, 1879-355xelectronic), 2013 Oct 1; 87(2): 304-310.
Export to BibTeX Export to EndNote
Paper type: Journal Article, Research Support, Non-U. S. Gov'T,
Impact factor: 4.176, 5-year impact factor: 4.441
Url: http://www.scopus.com/inward/record.url?eid=2-s2.0-84882862158&partnerID=40&md5=e9f427e1b6f183eaa27b85c16ee193bc
Keywords: Chemoradiation Therapies, Clinical Information, Methods And Materials, Multivariate Logistic Regressions, Receiver Operating Characteristic Curves, Resampling Technique, Spearman, S Rank Correlation Coefficients, Statistical Evidence, Biological Organs, Oncology, Patient Monitoring, Regression Analysis, Tissue, Heart, Adolescent, Adult, Aged, Article, Cancer Survivor, Chemoradiotherapy, Dosimetry, Female, Heart Left Atrium, Heart Left Ventricle, Heart Right Atrium, Heart Right Ventricle, Heart Volume, Hodgkin Disease, Human, Lung Volume, Major Clinical Study, Normal Tissue Complication Probability, Predictive Value, Priority Journal, Radiation Dose, Radiation Dose Distribution, Radiation Injury, Retrospective Study, Simulation, Valvular Heart Disease, Antineoplastic Combined Chemotherapy Protocols, Area Under Curve, Heart Valve Diseases, Middle Aged, Models, Multivariate Analysis, Organ Size, Radiation Injuries, Retrospective Studies, Young Adult,
Affiliations:
*** IBB - CNR ***
Institute of Biostructures and Bioimaging, National Council of Research, Naples, Italy. laura.cella@cnr.it
Department of Advanced Biomedical Sciences, Federico II University School of Medicine, Naples, Italy
References:
Darby, S.C., Cutter, D.J., Boerma, M., Radiation-related heart disease: Current knowledge and future prospects (2010) Int J Radiat Oncol Biol Phys, 76, pp. 656-66
Gagliardi, G., Constine, L.S., Moiseenko, V., Radiation dose-volume effects in the heart (2010) Int J Radiat Oncol Biol Phys, 76 (3 SUPPL.), pp. 77-S85
Cella, L., Conson, M., Caterino, M., Thyroid V30 predicts radiation-induced hypothyroidism in patients treated with sequential chemo-radiotherapy for Hodgkin's lymphoma (2012) Int J Radiat Oncol Biol Phys, 82, pp. 1802-1808
Engert, A., Plutschow, A., Eich, H.T., Reduced treatment intensity in patients with early-stage Hodgkin's lymphoma (2010) N Engl J Med, 363, pp. 640-652
Cella, L., Liuzzi, R., Conson, M., Dosimetric predictors of asymptomatic heart valvular dysfunction following mediastinal irradiation for Hodgkin's lymphoma (2011) Radiother Oncol, 101, pp. 316-321
Heidenreich, P.A., Hancock, S.L., Lee, B.K., Asymptomatic cardiac disease following mediastinal irradiation (2003) J Am Coll Cardiol, 42, pp. 743-749
Wethal, T., Lund, M.B., Edvardsen, T., Valvular dysfunction and left ventricular changes in Hodgkin's lymphoma survivors: A longitudinal study (2009) Br J Cancer, 101, pp. 575-581
Adams, M.J., Hardenbergh, P.H., Constine, L.S., Radiation-associated cardiovascular disease (2003) Crit Rev Oncol Hematol, 45, pp. 55-75
Ghobadi, G., Van Der Veen, S., Bartelds, B., Physiological interaction of heart and lung in thoracic irradiation (2012) Int J Radiat Oncol Biol Phys, 84, pp. 639-e646
Huang, E.X., Hope, A.J., Lindsay, P.E., Heart irradiation as a risk factor for radiation pneumonitis (2011) Acta Oncol, 50, pp. 51-60
El Naqa, I., Bradley, J., Blanco, A.I., Multivariable modeling of radiotherapy outcomes, including dose-volume and clinical factors (2006) Int J Radiat Oncol Biol Phys, 64, pp. 1275-1286
Feng, M., Moran, J.M., Koelling, T., Development and validation of a heart atlas to study cardiac exposure to radiation following treatment for breast cancer (2011) Int J Radiat Oncol Biol Phys, 79, pp. 10-18
El Naqa, I., Suneja, G., Lindsay, P.E., Dose response explorer: An integrated open-source tool for exploring and modelling radiotherapy dose-volume outcome relationships (2006) Phys Med Biol, 51, pp. 5719-5735
Trott, K.R., Doerr, W., Facoetti, A., Biological mechanisms of normal tissue damage: Importance for the design of NTCP models (2012) Radiother Oncol, 105, pp. 79-85
Van Der Schaaf, A., Xu, C.J., Van Luijk, P., Multivariate modeling of complications with data driven variable selection: Guarding against overfitting and effects of data set size (2012) Radiother Oncol, 105, pp. 115-121
Defraene, G., Van Den Bergh, L., Al-Mamgani, A., The benefits of including clinical factors in rectal normal tissue complication probability modeling after radiotherapy for prostate cancer (2012) Int J Radiat Oncol Biol Phys, 82, pp. 1233-1242
Van Luijk, P., Faber, H., Meertens, H., The impact of heart irradiation on dose-volume effects in the rat lung (2007) Int J Radiat Oncol Biol Phys, 69, pp. 552-559
Multivariate normal tissue complication probability modeling of heart valve dysfunction in Hodgkin lymphoma survivors
Purpose To establish a multivariate normal tissue complication probability (NTCP) model for radiation-induced asymptomatic heart valvular defects (RVD). Methods and Materials Fifty-six patients treated with sequential chemoradiation therapy for Hodgkin lymphoma (HL) were retrospectively reviewed for RVD events. Clinical information along with whole heart, cardiac chambers, and lung dose distribution parameters was collected, and the correlations to RVD were analyzed by means of Spearman's rank correlation coefficient (Rs). For the selection of the model order and parameters for NTCP modeling, a multivariate logistic regression method using resampling techniques (bootstrapping) was applied. Model performance was evaluated using the area under the receiver operating characteristic curve (AUC). Results When we analyzed the whole heart, a 3-variable NTCP model including the maximum dose, whole heart volume, and lung volume was shown to be the optimal predictive model for RVD (Rs = 0.573, P
Purpose To establish a multivariate normal tissue complication probability (NTCP) model for radiation-induced asymptomatic heart valvular defects (RVD). Methods and Materials Fifty-six patients treated with sequential chemoradiation therapy for Hodgkin lymphoma (HL) were retrospectively reviewed for RVD events. Clinical information along with whole heart, cardiac chambers, and lung dose distribution parameters was collected, and the correlations to RVD were analyzed by means of Spearman's rank correlation coefficient (Rs). For the selection of the model order and parameters for NTCP modeling, a multivariate logistic regression method using resampling techniques (bootstrapping) was applied. Model performance was evaluated using the area under the receiver operating characteristic curve (AUC). Results When we analyzed the whole heart, a 3-variable NTCP model including the maximum dose, whole heart volume, and lung volume was shown to be the optimal predictive model for RVD (Rs = 0.573, P
Multivariate normal tissue complication probability modeling of heart valve dysfunction in Hodgkin lymphoma survivors
No results. |
Multivariate normal tissue complication probability modeling of heart valve dysfunction in Hodgkin lymphoma survivors
Other filter: ([btitle,keywords] "Chemoradiation Thera ...
Di Lascio N, Avigo C, Salvati A, Martini N, Ragucci M, Monti S, Prinster A, Chiappino D, Mancini M, D'Elia D, Ghiadoni L, Bonino F, Brunetto MR, Faita F
* Steato-Score: Non-Invasive Quantitative Assessment of Liver Fat by Ultrasound Imaging (406 views)
Ultrasound Med Biol (ISSN: 0301-5629, 0301-5629linking), 2018; 44(8): 1585-1596.
Impact Factor: 2.494
View Export to BibTeX Export to EndNote
Cella L, Conson M, Caterino M, De Rosa N, Liuzzi R, Picardi M, Grimaldi F, Solla R, Farella A, Salvatore M, Pacelli R
* Thyroid V30 predicts radiation-induced hypothyroidism in patients treated with sequential chemo-radiotherapy for Hodgkin's lymphoma (489 views) (PDF 236 views)
Int J Radiat Oncol (ISSN: 0360-3016, 1879-355x, 1879-355xelectronic), 2012 Apr 1; 82(5): 1802-1808.
Impact Factor: 4.524
View Export to BibTeX Export to EndNote
* Steato-Score: Non-Invasive Quantitative Assessment of Liver Fat by Ultrasound Imaging (406 views)
Ultrasound Med Biol (ISSN: 0301-5629, 0301-5629linking), 2018; 44(8): 1585-1596.
Impact Factor: 2.494
View Export to BibTeX Export to EndNote
Cella L, Conson M, Caterino M, De Rosa N, Liuzzi R, Picardi M, Grimaldi F, Solla R, Farella A, Salvatore M, Pacelli R
* Thyroid V30 predicts radiation-induced hypothyroidism in patients treated with sequential chemo-radiotherapy for Hodgkin's lymphoma (489 views) (PDF 236 views)
Int J Radiat Oncol (ISSN: 0360-3016, 1879-355x, 1879-355xelectronic), 2012 Apr 1; 82(5): 1802-1808.
Impact Factor: 4.524
View Export to BibTeX Export to EndNote
2 Records (2 excluding Abstracts).
Total impact factor: 7.018 (7.018 excluding Abstracts).
Total 5 year impact factor: 7.332 (7.332 excluding Abstracts).
Total impact factor: 7.018 (7.018 excluding Abstracts).
Total 5 year impact factor: 7.332 (7.332 excluding Abstracts).
390 views. Last view on Saturday 14 January 2023, 17:50:36
ibb.cnr.it