Impact of diabetes on cardiac sympathetic innervation in patients with heart failure: a 123I meta-iodobenzylguanidine (123I MIBG) scintigraphic study (365 views)
Diabetes Care (ISSN: 1935-5548, 0149-5992), 2013 Sep; 36(8): 2395-2401.
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Paper type: Journal Article,
Impact factor: 8.57, 5-year impact factor: 8.462
Url: http://www.scopus.com/inward/record.url?eid=2-s2.0-84885984550&partnerID=40&md5=6954dcdce4452fb9660192558219e382
Keywords: (3 Iodobenzyl)guanidine I 123, Aldosterone Antagonist, Angiotensin 1 Receptor Antagonist, Beta Adrenergic Receptor Blocking Agent, Bisoprolol, Calcium Channel Blocking Agent, Carvedilol, Dipeptidyl Carboxypeptidase Inhibitor, Glucose, Hemoglobin A1c, Insulin, Loop Diuretic Agent, Oral Antidiabetic Agent, Article, Clinical Assessment, Controlled Study, Diet Therapy, Disease Course, Disease Severity, Echocardiography, Female, Glucose Blood Level, Glycemic Control, Heart Failure, Heart Function, Heart Left Ventricle Ejection Fraction, Human, Major Clinical Study, Non Insulin Dependent Diabetes Mellitus, Protein Analysis, Risk Factor, Sympathetic Tone,
Affiliations:
*** IBB - CNR ***
Department of Advanced Biomedical Sciences, Section of Cardiology, Federico II University, Naples,Italy.
Division of Cardiology, Salvatore Maugeri Foundation, IRCCS, Institute of Telese Terme, Telese Terme (BN), Italy
Department of Translational Medical Sciences, Section of Geriatrics, Federico II University, Naples, Italy
Institute of Biostructures, Bioimages of the National Council of Research, Naples, Italy
Department of Cardiology, Fatebenefratelli Hospital, Naples, Italy
Department of Molecular Medicine and Medical Biotechnologies, Federico II University, Naples, Italy
SDN Foundation, Institute of Diagnostic and Nuclear Development, Naples, Italy
References:
Not available.
Diabetes Care (ISSN: 1935-5548, 0149-5992), 2013 Sep; 36(8): 2395-2401.
Export to BibTeX Export to EndNote
Paper type: Journal Article,
Impact factor: 8.57, 5-year impact factor: 8.462
Url: http://www.scopus.com/inward/record.url?eid=2-s2.0-84885984550&partnerID=40&md5=6954dcdce4452fb9660192558219e382
Keywords: (3 Iodobenzyl)guanidine I 123, Aldosterone Antagonist, Angiotensin 1 Receptor Antagonist, Beta Adrenergic Receptor Blocking Agent, Bisoprolol, Calcium Channel Blocking Agent, Carvedilol, Dipeptidyl Carboxypeptidase Inhibitor, Glucose, Hemoglobin A1c, Insulin, Loop Diuretic Agent, Oral Antidiabetic Agent, Article, Clinical Assessment, Controlled Study, Diet Therapy, Disease Course, Disease Severity, Echocardiography, Female, Glucose Blood Level, Glycemic Control, Heart Failure, Heart Function, Heart Left Ventricle Ejection Fraction, Human, Major Clinical Study, Non Insulin Dependent Diabetes Mellitus, Protein Analysis, Risk Factor, Sympathetic Tone,
Affiliations:
*** IBB - CNR ***
Department of Advanced Biomedical Sciences, Section of Cardiology, Federico II University, Naples,Italy.
Division of Cardiology, Salvatore Maugeri Foundation, IRCCS, Institute of Telese Terme, Telese Terme (BN), Italy
Department of Translational Medical Sciences, Section of Geriatrics, Federico II University, Naples, Italy
Institute of Biostructures, Bioimages of the National Council of Research, Naples, Italy
Department of Cardiology, Fatebenefratelli Hospital, Naples, Italy
Department of Molecular Medicine and Medical Biotechnologies, Federico II University, Naples, Italy
SDN Foundation, Institute of Diagnostic and Nuclear Development, Naples, Italy
References:
Not available.
Impact of diabetes on cardiac sympathetic innervation in patients with heart failure: a 123I meta-iodobenzylguanidine (123I MIBG) scintigraphic study
OBJECTIVE: Impaired parasympathetic and sympathetic nervous system activity have been demonstrated in patients with diabetes mellitus (DM) and correlated with worse prognosis. Few data are available on the effect of DM on cardiac neuropathy in heart failure (HF). The aim of the current study was to assess cardiac sympathetic activity in HF patients with and without DM.; RESEARCH DESIGN AND METHODS: Patients with severe HF (n = 75), with (n = 37) and without DM (n = 38), and 14 diabetic patients with normal cardiac function underwent (123)I meta-iodobenzylguanidine scintigraphy from which early and late heart-to-mediastinum (H/M) ratios were calculated. Clinical, echocardiographic, and biochemical data were measured.; RESULTS: DM compared with non-DM patients showed significantly lower early (1.65 ± 0.21 vs. 1.75 ± 0.21; P < 0.05) and late H/M ratios (1.46 ± 0.22 vs. 1.58 ± 0.24; P < 0.03). Early and late H/M were significantly higher in DM patients without HF (2.22 ± 0.35 and 1.99 ± 0.24, respectively) than HF patients with (P < 0.0001) and without (P < 0.0001) DM. In HF patients, an inverse correlation between early or late H/M ratio and hemoglobin A1c (HbA1c) (Pearson = -0.473, P = 0.001; Pearson = -0.382, P = 0.001, respectively) was observed. In DM, in multivariate analysis, HbA1c and ejection fraction remained significant predictors of early H/M; HbA1c remained the only significant predictor of late H/M. No correlation between early or late H/M and HbA1c was found in non-DM patients.; CONCLUSIONS: Diabetic patients with HF show lower cardiac sympathetic activity than HF patients not having DM or than DM patients with a similar degree of autonomic dysfunction not having HF. HbA1c correlated with the degree of reduction in cardiac sympathetic activity.
OBJECTIVE: Impaired parasympathetic and sympathetic nervous system activity have been demonstrated in patients with diabetes mellitus (DM) and correlated with worse prognosis. Few data are available on the effect of DM on cardiac neuropathy in heart failure (HF). The aim of the current study was to assess cardiac sympathetic activity in HF patients with and without DM.; RESEARCH DESIGN AND METHODS: Patients with severe HF (n = 75), with (n = 37) and without DM (n = 38), and 14 diabetic patients with normal cardiac function underwent (123)I meta-iodobenzylguanidine scintigraphy from which early and late heart-to-mediastinum (H/M) ratios were calculated. Clinical, echocardiographic, and biochemical data were measured.; RESULTS: DM compared with non-DM patients showed significantly lower early (1.65 ± 0.21 vs. 1.75 ± 0.21; P < 0.05) and late H/M ratios (1.46 ± 0.22 vs. 1.58 ± 0.24; P < 0.03). Early and late H/M were significantly higher in DM patients without HF (2.22 ± 0.35 and 1.99 ± 0.24, respectively) than HF patients with (P < 0.0001) and without (P < 0.0001) DM. In HF patients, an inverse correlation between early or late H/M ratio and hemoglobin A1c (HbA1c) (Pearson = -0.473, P = 0.001; Pearson = -0.382, P = 0.001, respectively) was observed. In DM, in multivariate analysis, HbA1c and ejection fraction remained significant predictors of early H/M; HbA1c remained the only significant predictor of late H/M. No correlation between early or late H/M and HbA1c was found in non-DM patients.; CONCLUSIONS: Diabetic patients with HF show lower cardiac sympathetic activity than HF patients not having DM or than DM patients with a similar degree of autonomic dysfunction not having HF. HbA1c correlated with the degree of reduction in cardiac sympathetic activity.
Impact of diabetes on cardiac sympathetic innervation in patients with heart failure: a 123I meta-iodobenzylguanidine (123I MIBG) scintigraphic study
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Impact of diabetes on cardiac sympathetic innervation in patients with heart failure: a 123I meta-iodobenzylguanidine (123I MIBG) scintigraphic study
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View Export to BibTeX Export to EndNote
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Impact Factor: 5.537
View Export to BibTeX Export to EndNote
Petretta M, Pellegrino T, Cuocolo A
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Impact Factor: 5.383
View Export to BibTeX Export to EndNote
Petretta M, Pellegrino T, Cuocolo A
* The "gray Zone" For The Heart To Mediastinum Mibg Uptake Ratio (385 views)
J Nucl Cardiol (ISSN: 1071-3581, 1532-6551, 1532-6551electronic), 2014; 21(5): 921-924.
Impact Factor: 2.942
View Export to BibTeX Export to EndNote
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* Reduced Cardiac 123i-Metaiodobenzylguanidine Uptake In Patients With Spinocerebellar Ataxia Type 2: A Comparative Study With Parkinson'S Disease (714 views)
Eur J Nucl Med (ISSN: 1619-7089, 1619-7070, 0340-6997), 2013 Dec; 40(12): 1914-1921.
Impact Factor: 2.692
View Export to BibTeX Export to EndNote
Pellegrino T, Petretta M, Paolillo S, Boemio A, Carotenuto R, Petretta MP, Di Nuzzo C, Perrone-filardi P, Cuocolo A
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Eur J Nucl Med (ISSN: 1619-7089, 1619-7070, 0340-6997), 2013 Oct; 40(10): 1549-1557.
Impact Factor: 5.217
View Export to BibTeX Export to EndNote
Giallauria F, Acampa W, Ricci F, Gallicchio R, Xhoxhi E, Vitelli A, D'Agostino M, Lucci R, Vigorito C, Cuocolo A
* Effects of exercise training started within 2 weeks after acute myocardial infarction on myocardial perfusion and left ventricular function: A gated SPECT imaging study (507 views)
Eur J Prev Cardiol (ISSN: 2047-4873, 2047-4881), 2012 Dec; 19(6): 1410-1419.
Impact Factor: 2.675
View Export to BibTeX Export to EndNote
Maurea S, Cuocolo A, Imbriaco M, Pellegrino T, Fusari M, Cuocolo R, Liuzzi R, Salvatore M
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Impact Factor: 1.41
View Export to BibTeX Export to EndNote
Sorriento D, Santulli G, Del Giudice C, Anastasio A, Trimarco B, Iaccarino G
* Endothelial cells are able to synthesize and release catecholamines both in vitro and in vivo (514 views)
Hypertensionhypertension (ISSN: 0194-911x), 2012; 60(1): 129-136.
Impact Factor: 6.873
View Export to BibTeX Export to EndNote
Perrone-Filardi P, Paolillo S, Dellegrottaglie S, Gargiulo P, Savarese G, Marciano C, Casaretti L, Cecere M, Musella F, Pirozzi E, Parente A, Cuocolo A
* Assessment of cardiac sympathetic activity by MIBG imaging in patients with heart failure: a clinical appraisal (367 views)
Heart (ISSN: 1468-201x, 1355-6037), 2011 Nov; 97(22): 1828-1833.
Impact Factor: 4.223
View Export to BibTeX Export to EndNote
Manganelli F, Spadafora M, Varrella P, Peluso G, Sauro R, Di Lorenzo E, Rosato G, Daniele S, Cuocolo A
* Addition of atropine to submaximal exercise stress testing in patients evaluated for suspected ischaemia with SPECT imaging: a randomized, placebo-controlled trial (473 views)
Eur J Nucl Med (ISSN: 1619-7089, 1619-7070, 0340-6997), 2011 Feb; 38(2): 245-251.
Impact Factor: 4.991
View Export to BibTeX Export to EndNote
Pedone C, Di Pasquale G, Greco C, Gonzini L, Maggioni AP, Pavesi PC, Sabini A, Boccanelli A; In-Acs Outcome Investigators
* Prescription at discharge of recommended treatments for secondary prevention in patients with ST-segment elevation myocardial infarction according to reperfusion strategies. Results from the IN-ACS outcome study (537 views)
Acute Cardiac Care (ISSN: 1748-295x, 1748-2941), 2009; 11(4): 222-228.
Impact Factor: 0
View Export to BibTeX Export to EndNote
Ferro A, Pellegrino T, Spinelli L, Acampa W, Petretta M, Cuocolo A
* Comparison Between Dobutamine Echocardiography and Single-Photon Emission Computed Tomography for Interpretive Reproducibility (589 views)
Am J Cardiol (ISSN: 0002-9149), 2007 Oct 15; 100(8): 1239-1244.
Impact Factor: 3.603
View Export to BibTeX Export to EndNote
Maestri R, Pinna G, Accardo A, Allegrini P, Balocchi R, D'ADDIO G, Ferrario M, Menicucci D, Porta A, Sassi R
* Nonlinear indices of heart rate variability in chronic heart failure patients: Redundancy and comparative clinical value (454 views)
J Cardiovasc Electrophysiol (ISSN: 1045-3873), 2007; 18(4): 425-433.
Impact Factor: 3.475
View Export to BibTeX Export to EndNote
Hesse B, Tagil K, Cuocolo A, Anagnostopoulos C, Bardies M, Bax J, Bengel F, Busemann Sokole E, Davies G, Dondi M, Edenbrandt L, Franken P, Kjaer A, Knuuti J, Lassmann M, Ljungberg M, Marcassa C, Marie PY, Mckiddie F, O'connor M, Prvuolovich E, Underwood R
* 3. 0 T perfusion MR imaging (878 views)
Rivista Di Neuroradiologia (ISSN: 1120-9976), 2004; 17(6): 807-812.
Impact Factor: 0.023
View Export to BibTeX Export to EndNote
Biondi B, Fazio S, Cuocolo A, Sabatini D, Nicolai E, Lombardi G, Salvatore M, Sacca L
Impaired cardiac reserve and exercise capacity in patients receiving long-term thyrotropin suppressive therapy with levothyroxine (416 views)
J Clin Endocrinol Metab (ISSN: 0021-972x), 1996 Dec; 81(12): 4224-4228.
Impact Factor: 4.575
View Export to BibTeX Export to EndNote
Maurea S, Lastoria S, Caracò C, Klain M, Varrella P, Acampa W, Muto P, Salvatore M
The role of radiolabeled somatostatin analogs in adrenal imaging (472 views)
Nucl Med Biol (ISSN: 0969-8051, 0883-2897), 1996 Sep; 23(6): 677-680.
Impact Factor: 1.042
View Export to BibTeX Export to EndNote
Marotta T, Ferrara LA, Di Marino L, Mancini M, Annuzzi G, Russo O, D'Orta G, Lucarelli C, Rossi F
Factors affecting lipoprotein lipase in hypertensive patients (522 views)
Metab Clin Exp (ISSN: 0026-0495, 1532-8600), 1995 Jun; 44(6): 712-718.
Impact Factor: 1.681
View Export to BibTeX Export to EndNote
Maurea S, Lastoria S, Cuocolo A, Celentano L, Salvatore M
The diagnosis of nonfunctioning pheochromocytoma the role of I-123 MIBG imaging (291 views)
Clin Nucl Med (ISSN: 0363-9762, 1536-0229, 1536-0229electronic), 1995 Jan; 20(1): 22-24.
Impact Factor: 0.34
View Export to BibTeX Export to EndNote
Lastoria S, Caraco C, Maurea S, Piroli C, Maurelli L, Vergara E, Klain M, Cuocolo A, Salvatore M
Evaluation of orbital involvement by neuroblastoma using radiolabeled metaiodobenzylguanidine (301 views)
Ital J Ophthalmol (ISSN: 0394-610x), 1993; 7(3): 147-152.
Impact Factor: 0
View Export to BibTeX Export to EndNote
20 Records (20 excluding Abstracts).
Total impact factor: 56.682 (56.682 excluding Abstracts).
Total 5 year impact factor: 65.268 (65.268 excluding Abstracts).
Total impact factor: 56.682 (56.682 excluding Abstracts).
Total 5 year impact factor: 65.268 (65.268 excluding Abstracts).
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