The crystal structure of the streptococcal collagen-like protein 2 globular domain from invasive M3-type group a streptococcus shows significant similarity to immunomodulatory HIV protein gp41
The crystal structure of the streptococcal collagen-like protein 2 globular domain from invasive M3-type group a streptococcus shows significant similarity to immunomodulatory HIV protein gp41(420 views) Squeglia F, Bachert B, De Simone A, Lukomski S, Berisio R
Keywords: Bacterial Protein, Fusion Proteins, Globular Domains, High-Resolution Structures, Immuno Modulations, Immunomodulatory, Structural Basis, Structural Descriptions, Crystal Structure, Collagen, Glycoprotein Gp 41, Streptococcal Collagen Like Protein 2, Unclassified Drug, Adhesion, Amino Acid Sequence, Amino Terminal Sequence, Article, Bacterial Strain, Biofilm, Controlled Study, Crystallography, Host Pathogen Interaction, Human, Human Immunodeficiency Virus 1, Hydrophobicity, Immunomodulation, Molecular Dynamics, Molecular Model, Nonhuman, Phylogeny, Polymerization, Priority Journal, Protein Domain, Protein Expression, Protein Function, Protein Structure, Sequence Alignment, Sequence Analysis, Species Invasion, Streptococcus Pyogenes, T Lymphocyte, Trimerization, Protein Folding, X-Ray, Hiv Envelope Protein Gp41, Immunologic Factors, Molecular Dynamics Simulation, Molecular Sequence Data, Secondary, Tertiary, Structural Homology, Bacterial Proteins Chemistry Metabolism, Collagen Chemistry Metabolism, Hiv Envelope Protein Gp41 Chemistry, Immunologic Factors Chemistry, Streptococcus Pyogenes Metabolism,
Affiliations: *** IBB - CNR ***
Institute of Biostructures and Bioimaging, Consiglio Nazionale Delle Ricerche, Via Mezzocannone 16, I-80134 Napoli, Italy
Department of Microbiology, Immunology and Cell Biology, West Virginia University, School of Medicine, Morgantown, West Virginia 26506, United States
Division of Molecular Biosciences, Imperial College London, London SW7 2AZ, United Kingdom
From the Institute of Biostructures and Bioimaging, Consiglio Nazionale delle Ricerche, Via Mezzocannone 16, I-80134 Napoli, Italy.
References: Bisno, A.L., Rubin, F.A., Cleary, P.P., Dale, J.B., Prospects for a group A streptococcal vaccine: Rationale, feasibility, and obstacles-report of a National Institute of Allergy and Infectious Diseases workshop (2005) Clin. Infect. Dis., 41, pp. 1150-115
Kaul, R., McGeer, A., Low, D.E., Green, K., Schwartz, B., Simor, A.E., Population-based surveillance for group A streptococcal necrotizing fasciitis: Clinical features, prognostic indicators, and microbiologic analysis of seventy-seven cases (1997) Am. J. Med., 103, pp. 18-24
Sharkawy, A., Low, D.E., Saginur, R., Gregson, D., Schwartz, B., Jessamine, P., Green, K., McGeer, A., Severe group A streptococcal soft tissue infections in Ontario: 1992-1996 (2002) Clin. Infect. Dis., 34, pp. 454-460. , Ontario Group A Streptococcal Study Group
Carapetis, J.R., Steer, A.C., Mulholland, E.K., Weber, M., The global burden of group A streptococcal diseases (2005) Lancet Infect. Dis., 5, pp. 685-694
Musser, J.M., Hauser, A.R., Kim, M.H., Schlievert, P.M., Nelson, K., Selander, R.K., Streptococcus pyogenes causing toxic-shock-like syndrome and other invasive diseases: Clonal diversity and pyrogenic exotoxin expression (1991) Proc. Natl. Acad. Sci. U.S.A., 88, pp. 2668-2672
Beres, S.B., Sylva, G.L., Barbian, K.D., Lei, B., Hoff, J.S., Mammarella, N.D., Liu, M.-Y., Musser, J.M., Genome sequence of a serotype M3 strain of group A Streptococcus: Phage-encoded toxins, the high-virulence phenotype, and clone emergence (2002) Proc. Natl. Acad. Sci. U.S.A., 99, pp. 10078-10083
Beres, S.B., Carroll, R.K., Shea, P.R., Sitkiewicz, I., Martinez-Gutierrez, J.C., Low, D.E., McGeer, A., Musser, J.M., Molecular complexity of successive bacterial epidemics deconvoluted by comparative pathogenomics (2010) Proc. Natl. Acad. Sci. U.S.A., 107, pp. 4371-4376
Olsen, R.J., Musser, J.M., Molecular pathogenesis of necrotizing fasciitis (2010) Annu. Rev. Pathol., 5, pp. 1-31
Nakagawa, I., Kurokawa, K., Yamashita, A., Nakata, M., Tomiyasu, Y., Okahashi, N., Kawabata, S., Hamada, S., Genome sequence of an M3 strain of Streptococcus pyogenes reveals a large-scale genomic rearrangement in invasive strains and new insights into phage evolution (2003) Genome Res., 13, pp. 1042-1055
Lukomski, S., Nakashima, K., Abdi, I., Cipriano, V.J., Ireland, R.M., Reid, S.D., Adams, G.G., Musser, J.M., Identification and characterization of the scl gene encoding a group A Streptococcus extracellular protein virulence factor with similarity to human collagen (2000) Infect. Immun., 68, pp. 6542-6553
Rasmussen, M., Björck, L., Unique regulation of SclB-A novel collagen-like surface protein of Streptococcus pyogenes (2001) Mol. Microbiol., 40, pp. 1427-1438
Rasmussen, M., Edén, A., Björck, L., SclA, a novel collagen-like surface protein of Streptococcus pyogenes (2000) Infect. Immun., 68, pp. 6370-6377
Whatmore, A.M., Streptococcus pyogenes sclB encodes a putative hypervariable surface protein with a collagen-like repetitive structure (2001) Microbiology, 147, pp. 419-429
Xu, Y., Keene, D.R., Bujnicki, J.M., Höök, M., Lukomski, S., Streptococcal Scl1 and Scl2 proteins form collagen-like triple helices (2002) J. Biol. Chem., 277, pp. 27312-27318
Mohs, A., Silva, T., Yoshida, T., Amin, R., Lukomski, S., Inouye, M., Brodsky, B., Mechanism of stabilization of a bacterial collagen triple helix in the absence of hydroxyproline (2007) J. Biol. Chem., 282, pp. 29757-29765
Han, R., Caswell, C.C., Lukomska, E., Keene, D.R., Pawlowski, M., Bujnicki, J.M., Kim, J.K., Lukomski, S., Binding of the low-density lipoprotein by streptococcal collagen-like protein Scl1 of Streptococcus pyogenes (2006) Mol. Microbiol., 61, pp. 351-367
Berisio, R., Vitagliano, L., Polyproline and triple helix motifs in host-pathogen recognition (2012) Curr. Protein Pept. Sci., 13, pp. 855-865
Berisio, R., De Simone, A., Ruggiero, A., Improta, R., Vitagliano, L., Role of side chains in collagen triple helix stabilization and partner recognition (2009) J. Pept. Sci., 15, pp. 131-140
Improta, R., Berisio, R., Vitagliano, L., Contribution of dipoledipole interactions to the stability of the collagen triple helix (2008) Protein Sci., 17, pp. 955-961
Yu, Z., Brodsky, B., Inouye, M., Dissecting a bacterial collagen domain from Streptococcus pyogenes: Sequence and length-dependent variations in triple helix stability and folding (2011) J. Biol. Chem., 286, pp. 18960-18968
Yu, Z., Mirochnitchenko, O., Xu, C., Yoshizumi, A., Brodsky, B., Inouye, M., Noncollagenous region of the streptococcal collagen-like protein is a trimerization domain that supports refolding of adjacent homologous and heterologous collagenous domains (2010) Protein Sci., 19, pp. 775-785
Caswell, C.C., Oliver-Kozup, H., Han, R., Lukomska, E., Lukomski, S., Scl1, the multifunctional adhesin of group A Streptococcus, selectively binds cellular fibronectin and laminin, and mediates pathogen internalization by human cells (2010) FEMS Microbiol. Lett., 303, pp. 61-68
Gao, Y., Liang, C., Zhao, R., Lukomski, S., Han, R., The Scl1 of M41-type group A Streptococcus binds the high-density lipoprotein (2010) FEMS Microbiol. Lett., 309, pp. 55-61
Pahlman, L.I., Marx, P.F., Mörgelin, M., Lukomski, S., Meijers, J.C., Herwald, H., Thrombin-activatable fibrinolysis inhibitor binds to Streptococcus pyogenes by interacting with collagen-like proteins A and B (2007) J. Biol. Chem., 282, pp. 24873-24881
Caswell, C.C., Han, R., Hovis, K.M., Ciborowski, P., Keene, D.R., Marconi, R.T., Lukomski, S., The Scl1 protein of M6-type group A Streptococcus binds the human complement regulatory protein, factor H, and inhibits the alternative pathway of complement (2008) Mol. Microbiol., 67, pp. 584-596
Reuter, M., Caswell, C.C., Lukomski, S., Zipfel, P.F., Binding of the human complement regulators CFHR1 and factor H by streptococcal collagen-like protein 1 (Scl1) via their conserved C termini allows control of the complement cascade at multiple levels (2010) J. Biol. Chem., 285, pp. 38473-38485
Humtsoe, J.O., Kim, J.K., Xu, Y., Keene, D.R., Höök, M., Lukomski, S., Wary, K.K., Astreptococcal collagen-like protein interacts with the a2b1 integrin and induces intracellular signaling (2005) J. Biol. Chem., 280, pp. 13848-13857
Caswell, C.C., Barczyk, M., Keene, D.R., Lukomska, E., Gullberg, D.E., Lukomski, S., Identification of the first prokaryotic collagen sequence motif that mediates binding to human collagen receptors, integrins 21 and 111 (2008) J. Biol. Chem., 283, pp. 36168-36175
Squeglia, F., Bachert, B., Romano, M., Lukomski, S., Berisio, R., Crystallization and preliminary x-ray crystallographic analysis of the variable domain of Scl2. 3 a streptococcal collagen-like protein from invasive M3-type Streptococcus pyogenes (2013) Acta Crystallogr. Sect. F Struct. Biol. Cryst. Commun., 69, pp. 1023-1025
Otwinowski, Z., Minor, W., (1997) Methods Enzymol, 276, pp. 307-326
Ruggiero, A., Squeglia, F., Marasco, D., Marchetti, R., Molinaro, A., Berisio, R., X-ray structural studies of the entire extracellular region of the serine/threonine kinase PrkC from Staphylococcus aureus (2011) Biochem. J., 435, pp. 33-41
Sheldrick, G.M., A short history of SHELX (2008) Acta Crystallogr. A, 64, pp. 112-122
Terwilliger, T., SOLVE and RESOLVE: Automated structure solution, density modification and model building (2004) J. Synchrotron Radiat., 11, pp. 49-52
Langer, G., Cohen, S.X., Lamzin, V.S., Perrakis, A., Automated macromolecular model building for x-ray crystallography using ARP/ wARP version 7 (2008) Nat. Protoc., 3, pp. 1171-1179
Potterton, E., Briggs, P., Turkenburg, M., Dodson, E., A graphical user interface to the CCP4 program suite (2003) Acta Crystallogr. D Biol. Crystallogr., 59, pp. 1131-1137
Cheng, T.J., Sung, M.T., Liao, H.Y., Chang, Y.F., Chen, C.W., Huang, C.Y., Chou, L.Y., Cheng, W.C., Domain requirement of moenomycin binding to bifunctional transglycosylases and development of high-throughput discovery of antibiotics (2008) Proc. Natl. Acad. Sci. U.S.A., 105, pp. 431-436
Lindorff-Larsen, K., Piana, S., Palmo, K., Maragakis, P., Klepeis, J.L., Dror, R.O., Shaw, D.E., Improved side-chain torsion potentials for the Amber ff99SB protein force field (2010) Proteins, 78, pp. 1950-1958
Horn, H.W., Swope, W.C., Pitera, J.W., Madura, J.D., Dick, T.J., Hura, G.L., Head-Gordon, T., Development of an improved four-site water model for biomolecular simulations: TIP4P-Ew (2004) J. Chem. Phys., 120, pp. 9665-9678
Bussi, G., Donadio, D., Parrinello, M., Canonical sampling through velocity rescaling (2007) J. Chem. Phys., 126, p. 014101
Berendsen, H.J.C., Postma, J.P.M., Van Gunsteren, W.F., Dinola, A., Haak, J.R., Molecular dynamics with coupling to an external bath (1984) J. Chem. Phys., 81, pp. 3684-3690
Walshaw, J., Woolfson, D.N., Socket: A program for identifying and analysing coiled-coil motifs within protein structures (2001) J. Mol. Biol., 307, pp. 1427-1450
Stetefeld, J., Frank, S., Jenny, M., Schulthess, T., Kammerer, R.A., Boudko, S., Landwehr, R., Engel, J., Collagen stabilization at atomic level: Crystal structure of designed (GlyProPro)10foldon (2003) Structure, 11, pp. 339-346
De Simone, A., Vitagliano, L., Berisio, R., Role of hydration in collagen triple helix stabilization (2008) Biochem. Biophys. Res. Commun., 372, pp. 121-125
Raman, S.S., Parthasarathi, R., Subramanian, V., Ramasami, T., Role of aspartic acid in collagen structure and stability: A molecular dynamics investigation (2006) J. Phys. Chem. B, 110, pp. 20678-20685
Oliver-Kozup, H., Martin, K.H., Schwegler-Berry, D., Green, B.J., Betts, C., Shinde, A.V., Van De Water, L., Lukomski, S., The group A streptococcal collagen-like protein-1, Scl1, mediates biofilm formation by targeting the extra domain A-containing variant of cellular fibronectin expressed in wounded tissue (2013) Mol. Microbiol., 87, pp. 672-689
Oliver-Kozup, H.A., Elliott, M., Bachert, B.A., Martin, K.H., Reid, S.D., Schwegler-Berry, D.E., Green, B.J., Lukomski, S., The streptococcal collagen-like protein-1 (Scl1) is a significant determinant for biofilm formation by group A Streptococcus (2011) BMC Microbiol., 11, p. 262
Paterson, G.K., Nieminen, L., Jefferies, J.M., Mitchell, T.J., PclA, a pneumococcal collagen-like protein with selected strain distribution, contributes to adherence and invasion of host cells (2008) FEMS Microbiol. Lett., 285, pp. 170-176
Beres, S.B., Sesso, R., Pinto, S.W., Hoe, N.P., Porcella, S.F., Deleo, F.R., Musser, J.M., Genome sequence of a Lancefield group C Streptococcus zooepidemicus strain causing epidemic nephritis: New information about an old disease (2008) PLoS One, 3, pp. e3026
Karlström, A., Jacobsson, K., Flock, M., Flock, J.I., Guss, B., Identification of a novel collagen-like protein, SclC, in Streptococcus equi using signal sequence phage display (2004) Vet. Microbiol., 104, pp. 179-188
Shulman, S.T., Stollerman, G., Beall, B., Dale, J.B., Tanz, R.R., Temporal changes in streptococcal M protein types and the near-disappearance of acute rheumatic fever in the United States (2006) Clin. Infect. Dis., 42, pp. 441-447
Cheng, A.G., McAdow, M., Kim, H.K., Bae, T., Missiakas, D.M., Schneewind, O., Contribution of coagulases towards Staphylococcus aureus disease and protective immunity (2010) PLoS Pathog., 6, pp. e1001036
Cantisani, M., Falanga, A., Incoronato, N., Russo, L., De Simone, A., Morelli, G., Berisio, R., Galdiero, S., Conformational modifications of gB from herpes simplex virus type 1 analyzed by synthetic peptides (2013) J. Med. Chem., , 10.1021/jm400771k
Koellhoffer, J.F., Malashkevich, V.N., Harrison, J.S., Toro, R., Bhosle, R.C., Chandran, K., Almo, S.C., Lai, J.R., Crystal structure of the Marburg virus GP2 core domain in its postfusion conformation (2012) Biochemistry, 51, pp. 7665-7675
Lee, J.E., Fusco, M.L., Hessell, A.J., Oswald, W.B., Burton, D.R., Saphire, E.O., Structure of the Ebola virus glycoprotein bound to an antibody from a human survivor (2008) Nature, 454, pp. 177-182
Buzon, V., Natrajan, G., Schibli, D., Campelo, F., Kozlov, M.M., Weissenhorn, W., Crystal structure of HIV-1 gp41 including both fusion peptide and membrane proximal external regions (2010) PLoS Pathog., 6, pp. e1000880
Heldwein, E.E., Lou, H., Bender, F.C., Cohen, G.H., Eisenberg, R.J., Harrison, S.C., Crystal structure of glycoprotein B from herpes simplex virus 1 (2006) Science, 313, pp. 217-220
Tran, E.E., Borgnia, M.J., Kuybeda, O., Schauder, D.M., Bartesaghi, A., Frank, G.A., Sapiro, G., Subramaniam, S., Structural mechanism of trimeric HIV-1 envelope glycoprotein activation (2012) PLoS Pathog., 8, pp. e1002797
Weissenhorn, W., Dessen, A., Harrison, S.C., Skehel, J.J., Wiley, D.C., Atomic structure of the ectodomain from HIV-1 gp41 (1997) Nature, 387, pp. 426-430
Boudko, S.P., Engel, J., Bächinger, H.P., The crucial role of trimerization domains in collagen folding (2012) Int. J. Biochem. Cell Biol., 44, pp. 21-32
Than, M.E., Henrich, S., Huber, R., Ries, A., Mann, K., Kühn, K., Timpl, R., Bode, W., The 1. 9-A crystal structure of the noncollagenous (NC1) domain of human placenta collagen IV shows stabilization via a novel type of covalent Met-Lys cross-link (2002) Proc. Natl. Acad. Sci. U.S.A., 99, pp. 6607-6612
Kvansakul, M., Bogin, O., Hohenester, E., Yayon, A., Crystal structure of the collagen 1(VIII) NC1 trimer (2003) Matrix Biol., 22, pp. 145-152
Bogin, O., Kvansakul, M., Rom, E., Singer, J., Yayon, A., Hohenester, E., Insight into Schmid metaphyseal chondrodysplasia from the crystal structure of the collagen X NC1 domain trimer (2002) Structure, 10, pp. 165-173
Wirz, J.A., Boudko, S.P., Lerch, T.F., Chapman, M.S., Bächinger, H.P., Crystal structure of the human collagen XV trimerization domain: A potent trimerizing unit common to multiplexin collagens (2011) Matrix Biol., 30, pp. 9-15
Boudko, S.P., Sasaki, T., Engel, J., Lerch, T.F., Nix, J., Chapman, M.S., Bächinger, H.P., Crystal structure of human collagen XVIII trimerization domain: A novel collagen trimerization fold (2009) J. Mol. Biol., 392, pp. 787-802
Réty, S., Salamitou, S., Garcia-Verdugo, I., Hulmes, D.J., Le Hégarat, F., Chaby, R., Lewit-Bentley, A., The crystal structure of the Bacillus anthracis spore surface protein BclA shows remarkable similarity to mammalian proteins (2005) J. Biol. Chem., 280, pp. 43073-43078
Cunningham, M.W., Pathogenesis of group A streptococcal infections (2000) Clin. Microbiol. Rev., 13, pp. 470-511
O'loughlin, R.E., Roberson, A., Cieslak, P.R., Lynfield, R., Gershman, K., Craig, A., Albanese, B.A., Van Beneden, C., The epidemiology of invasive group A streptococcal infection and potential vaccine implications: United States, 2000-2004 (2007) Clin. Infect. Dis., 45, pp. 853-862. , Active Bacterial Core Surveillance Team
Bisno, A. L., Rubin, F. A., Cleary, P. P., Dale, J. B., Prospects for a group A streptococcal vaccine: Rationale, feasibility, and obstacles-report of a National Institute of Allergy and Infectious Diseases workshop (2005) Clin. Infect. Dis., 41, pp. 1150-115
Carapetis, J. R., Steer, A. C., Mulholland, E. K., Weber, M., The global burden of group A streptococcal diseases (2005) Lancet Infect. Dis., 5, pp. 685-694
Musser, J. M., Hauser, A. R., Kim, M. H., Schlievert, P. M., Nelson, K., Selander, R. K., Streptococcus pyogenes causing toxic-shock-like syndrome and other invasive diseases: Clonal diversity and pyrogenic exotoxin expression (1991) Proc. Natl. Acad. Sci. U. S. A., 88, pp. 2668-2672
Beres, S. B., Sylva, G. L., Barbian, K. D., Lei, B., Hoff, J. S., Mammarella, N. D., Liu, M. -Y., Musser, J. M., Genome sequence of a serotype M3 strain of group A Streptococcus: Phage-encoded toxins, the high-virulence phenotype, and clone emergence (2002) Proc. Natl. Acad. Sci. U. S. A., 99, pp. 10078-10083
Beres, S. B., Carroll, R. K., Shea, P. R., Sitkiewicz, I., Martinez-Gutierrez, J. C., Low, D. E., McGeer, A., Musser, J. M., Molecular complexity of successive bacterial epidemics deconvoluted by comparative pathogenomics (2010) Proc. Natl. Acad. Sci. U. S. A., 107, pp. 4371-4376
Olsen, R. J., Musser, J. M., Molecular pathogenesis of necrotizing fasciitis (2010) Annu. Rev. Pathol., 5, pp. 1-31
Rasmussen, M., Bj rck, L., Unique regulation of SclB-A novel collagen-like surface protein of Streptococcus pyogenes (2001) Mol. Microbiol., 40, pp. 1427-1438
Rasmussen, M., Ed n, A., Bj rck, L., SclA, a novel collagen-like surface protein of Streptococcus pyogenes (2000) Infect. Immun., 68, pp. 6370-6377
Whatmore, A. M., Streptococcus pyogenes sclB encodes a putative hypervariable surface protein with a collagen-like repetitive structure (2001) Microbiology, 147, pp. 419-429
Xu, Y., Keene, D. R., Bujnicki, J. M., H k, M., Lukomski, S., Streptococcal Scl1 and Scl2 proteins form collagen-like triple helices (2002) J. Biol. Chem., 277, pp. 27312-27318
Caswell, C. C., Oliver-Kozup, H., Han, R., Lukomska, E., Lukomski, S., Scl1, the multifunctional adhesin of group A Streptococcus, selectively binds cellular fibronectin and laminin, and mediates pathogen internalization by human cells (2010) FEMS Microbiol. Lett., 303, pp. 61-68
Pahlman, L. I., Marx, P. F., M rgelin, M., Lukomski, S., Meijers, J. C., Herwald, H., Thrombin-activatable fibrinolysis inhibitor binds to Streptococcus pyogenes by interacting with collagen-like proteins A and B (2007) J. Biol. Chem., 282, pp. 24873-24881
Caswell, C. C., Han, R., Hovis, K. M., Ciborowski, P., Keene, D. R., Marconi, R. T., Lukomski, S., The Scl1 protein of M6-type group A Streptococcus binds the human complement regulatory protein, factor H, and inhibits the alternative pathway of complement (2008) Mol. Microbiol., 67, pp. 584-596
Humtsoe, J. O., Kim, J. K., Xu, Y., Keene, D. R., H k, M., Lukomski, S., Wary, K. K., Astreptococcal collagen-like protein interacts with the a2b1 integrin and induces intracellular signaling (2005) J. Biol. Chem., 280, pp. 13848-13857
Caswell, C. C., Barczyk, M., Keene, D. R., Lukomska, E., Gullberg, D. E., Lukomski, S., Identification of the first prokaryotic collagen sequence motif that mediates binding to human collagen receptors, integrins 21 and 111 (2008) J. Biol. Chem., 283, pp. 36168-36175
Sheldrick, G. M., A short history of SHELX (2008) Acta Crystallogr. A, 64, pp. 112-122
Cheng, T. J., Sung, M. T., Liao, H. Y., Chang, Y. F., Chen, C. W., Huang, C. Y., Chou, L. Y., Cheng, W. C., Domain requirement of moenomycin binding to bifunctional transglycosylases and development of high-throughput discovery of antibiotics (2008) Proc. Natl. Acad. Sci. U. S. A., 105, pp. 431-436
Horn, H. W., Swope, W. C., Pitera, J. W., Madura, J. D., Dick, T. J., Hura, G. L., Head-Gordon, T., Development of an improved four-site water model for biomolecular simulations: TIP4P-Ew (2004) J. Chem. Phys., 120, pp. 9665-9678
Berendsen, H. J. C., Postma, J. P. M., Van Gunsteren, W. F., Dinola, A., Haak, J. R., Molecular dynamics with coupling to an external bath (1984) J. Chem. Phys., 81, pp. 3684-3690
Raman, S. S., Parthasarathi, R., Subramanian, V., Ramasami, T., Role of aspartic acid in collagen structure and stability: A molecular dynamics investigation (2006) J. Phys. Chem. B, 110, pp. 20678-20685
Oliver-Kozup, H. A., Elliott, M., Bachert, B. A., Martin, K. H., Reid, S. D., Schwegler-Berry, D. E., Green, B. J., Lukomski, S., The streptococcal collagen-like protein-1 (Scl1) is a significant determinant for biofilm formation by group A Streptococcus (2011) BMC Microbiol., 11, p. 262
Paterson, G. K., Nieminen, L., Jefferies, J. M., Mitchell, T. J., PclA, a pneumococcal collagen-like protein with selected strain distribution, contributes to adherence and invasion of host cells (2008) FEMS Microbiol. Lett., 285, pp. 170-176
Beres, S. B., Sesso, R., Pinto, S. W., Hoe, N. P., Porcella, S. F., Deleo, F. R., Musser, J. M., Genome sequence of a Lancefield group C Streptococcus zooepidemicus strain causing epidemic nephritis: New information about an old disease (2008) PLoS One, 3, pp. e3026
Karlstr m, A., Jacobsson, K., Flock, M., Flock, J. I., Guss, B., Identification of a novel collagen-like protein, SclC, in Streptococcus equi using signal sequence phage display (2004) Vet. Microbiol., 104, pp. 179-188
Shulman, S. T., Stollerman, G., Beall, B., Dale, J. B., Tanz, R. R., Temporal changes in streptococcal M protein types and the near-disappearance of acute rheumatic fever in the United States (2006) Clin. Infect. Dis., 42, pp. 441-447
Cheng, A. G., McAdow, M., Kim, H. K., Bae, T., Missiakas, D. M., Schneewind, O., Contribution of coagulases towards Staphylococcus aureus disease and protective immunity (2010) PLoS Pathog., 6, pp. e1001036
Koellhoffer, J. F., Malashkevich, V. N., Harrison, J. S., Toro, R., Bhosle, R. C., Chandran, K., Almo, S. C., Lai, J. R., Crystal structure of the Marburg virus GP2 core domain in its postfusion conformation (2012) Biochemistry, 51, pp. 7665-7675
Lee, J. E., Fusco, M. L., Hessell, A. J., Oswald, W. B., Burton, D. R., Saphire, E. O., Structure of the Ebola virus glycoprotein bound to an antibody from a human survivor (2008) Nature, 454, pp. 177-182
Heldwein, E. E., Lou, H., Bender, F. C., Cohen, G. H., Eisenberg, R. J., Harrison, S. C., Crystal structure of glycoprotein B from herpes simplex virus 1 (2006) Science, 313, pp. 217-220
Tran, E. E., Borgnia, M. J., Kuybeda, O., Schauder, D. M., Bartesaghi, A., Frank, G. A., Sapiro, G., Subramaniam, S., Structural mechanism of trimeric HIV-1 envelope glycoprotein activation (2012) PLoS Pathog., 8, pp. e1002797
Boudko, S. P., Engel, J., B chinger, H. P., The crucial role of trimerization domains in collagen folding (2012) Int. J. Biochem. Cell Biol., 44, pp. 21-32
Than, M. E., Henrich, S., Huber, R., Ries, A., Mann, K., K hn, K., Timpl, R., Bode, W., The 1. 9-A crystal structure of the noncollagenous (NC1) domain of human placenta collagen IV shows stabilization via a novel type of covalent Met-Lys cross-link (2002) Proc. Natl. Acad. Sci. U. S. A., 99, pp. 6607-6612
Wirz, J. A., Boudko, S. P., Lerch, T. F., Chapman, M. S., B chinger, H. P., Crystal structure of the human collagen XV trimerization domain: A potent trimerizing unit common to multiplexin collagens (2011) Matrix Biol., 30, pp. 9-15
Boudko, S. P., Sasaki, T., Engel, J., Lerch, T. F., Nix, J., Chapman, M. S., B chinger, H. P., Crystal structure of human collagen XVIII trimerization domain: A novel collagen trimerization fold (2009) J. Mol. Biol., 392, pp. 787-802
R ty, S., Salamitou, S., Garcia-Verdugo, I., Hulmes, D. J., Le H garat, F., Chaby, R., Lewit-Bentley, A., The crystal structure of the Bacillus anthracis spore surface protein BclA shows remarkable similarity to mammalian proteins (2005) J. Biol. Chem., 280, pp. 43073-43078
Cunningham, M. W., Pathogenesis of group A streptococcal infections (2000) Clin. Microbiol. Rev., 13, pp. 470-511
O'loughlin, R. E., Roberson, A., Cieslak, P. R., Lynfield, R., Gershman, K., Craig, A., Albanese, B. A., Van Beneden, C., The epidemiology of invasive group A streptococcal infection and potential vaccine implications: United States, 2000-2004 (2007) Clin. Infect. Dis., 45, pp. 853-862. , Active Bacterial Core Surveillance Team
The crystal structure of the streptococcal collagen-like protein 2 globular domain from invasive M3-type group a streptococcus shows significant similarity to immunomodulatory HIV protein gp41
The crystal structure of the streptococcal collagen-like protein 2 globular domain from invasive M3-type group a streptococcus shows significant similarity to immunomodulatory HIV protein gp41
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The crystal structure of the streptococcal collagen-like protein 2 globular domain from invasive M3-type group a streptococcus shows significant similarity to immunomodulatory HIV protein gp41
Vitiello M, Finamore E, Falanga A, Raieta K, Cantisani M, Galdiero F, Pedone C, Galdiero M, Galdiero S * Fusion in Coq(479 views) Lecture Notes In Computer Science (ISSN: 0302-9743, 0302-974335404636319783540463634, 0302-974335402975459783540297543), 2001; 2178LNCS: 583-596. Impact Factor:0.415 ViewExport to BibTeXExport to EndNote
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