New derivative of carnosine for nanoparticle assemblies (458 views)
Eur J Med Chem (ISSN: 1768-3254, 0223-5234, 1768-3254electronic), 2013 Dec; 70: 225-232.
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Paper type: Journal Article, Research Support, Non-U. S. Gov'T,
Impact factor: 3.432, 5-year impact factor: 4.071
Url: http://www.scopus.com/inward/record.url?eid=2-s2.0-84886036303&partnerID=40&md5=6d10707b8b41c4de81d329c5c54bf92d
Keywords: Biotin, Carnosinase, Copper, Nanoparticles, Avidin Chemistry, Biotin Chemistry, Carnosine Chemical Synthesis Chemistry, Dipeptidases Blood Metabolism, Gold Chemistry, Humans, Metal Nanoparticles Chemistry, Molecular Structure, Spectrophotometry, Ultraviolet, Streptavidin Chemistry, Bio Nhs, Cupric Ion, Gold Nanoparticle, Unclassified Drug, Binding Assay, Drug Bioavailability, Drug Synthesis, Mass Spectrometry, Proton Nuclear Magnetic Resonance,
Affiliations:
*** IBB - CNR ***
Institute of Biostructure and Bioimaging, CNR, viale A. Doria 6, 95125 Catania, Italy. Electronic address: fbellia@unict.it.
Department of Chemical Sciences, University of Catania, viale A. Doria 6, 95125 Catania, Italy
References:
Gulewitsch, W., Amiradzibi, S., Carnosine, a new organic base from meat extracts (1900) Ber. Dtsch. Chem. Ges., 33, pp. 1902-190
Quinn, P.J., Boldyrev, A.A., Formazuyk, V.E., Carnosine: Its properties, functions and potential therapeutic applications (1992) Molecular Aspects of Medicine, 13 (5), pp. 379-444. , DOI 10.1016/0098-2997(92)90006-L
Decker, E.A., Livisay, S.A., Zhou, S., A re-evaluation of the antioxidant activity of purified carnosine (2000) Biochemistry (Moscow), 65, pp. 766-770
Kang, J.H., Kim, K.S., Choi, S.Y., Kwon, H.Y., Won, M.H., Kang, T.-C., Carnosine and related dipeptides protect human ceruloplasmin against peroxyl radical-mediated modification (2002) Molecules and Cells, 13 (3), pp. 498-502
Di Paola, R., Impellizzeri, D., Salinaro, A.T., Mazzon, E., Bellia, F., Cavallaro, M., Cornelius, C., Cuzzocrea, S., Administration of carnosine in the treatment of acute spinal cord injury (2011) Biochem. Pharmacol., 82, pp. 1478-1489
Renner, C., Zemitzsch, N., Fuchs, B., Geiger, K.D., Hermes, M., Hengstler, J., Gebhardt, R., Gaunitz, F., Carnosine retards tumor growth in vivo in an NIH3T3-HER2/neu mouse model (2010) Mol. Cancer, 9, p. 2
Ozel Turkcu, U., Bilgihan, A., Biberoglu, G., Mertoglu Caglar, O., Carnosine supplementation protects rat brain tissue against ethanol-induced oxidative stress (2010) Mol. Cell. Biochem., 339, pp. 55-61
Liu, W.H., Liu, T.C., Yin, M.C., Beneficial effects of histidine and carnosine on ethanol-induced chronic liver injury (2008) Food Chem. Toxicol., 46, pp. 1503-1509
Bellia, F., Vecchio, G., Cuzzocrea, S., Calabrese, V., Rizzarelli, E., Neuroprotective features of carnosine in oxidative driven diseases (2011) Mol. Aspects Med., 32, pp. 258-266
Hipkiss, A.R., Carnosine and its possible roles in nutrition and health (2009) Adv. Food Nutr. Res., 57, pp. 87-154
Teufel, M., Saudek, V., Ledig, J.-P., Bernhardt, A., Boularand, S., Carreau, A., Cairns, N.J., Smirnova, T., Sequence identification and characterization of human carnosinase and a closely related non-specific dipeptidase (2003) Journal of Biological Chemistry, 278 (8), pp. 6521-6531. , DOI 10.1074/jbc.M209764200
Bellia, F., Calabrese, V., Guarino, F., Cavallaro, M., Cornelius, C., De Pinto, V., Rizzarelli, E., Carnosinase levels in aging brain: Redox state induction and cellular stress response (2009) Antioxid. Redox Signal, 11, pp. 2759-2775
Lenney, J.F., Peppers, S.C., Kucera-Orallo, C.M., George, R.P., Characterization of human tissue carnosinase (1985) Biochemical Journal, 228 (3), pp. 653-660
Otani, H., Okumura, N., Hashida-Okumura, A., Nagai, K., Identification and characterization of a mouse dipeptidase that hydrolyzes l-carnosine (2005) J. Biochem. (Tokyo), 137, pp. 167-175
Bonomo, R.P., Bruno, V., Conte, E., De Guidi, G., La Mendola, D., Maccarrone, G., Nicoletti, F., Vecchio, G., Potentiometric, spectroscopic and antioxidant activity studies of SOD mimics containing carnosine (2003) Dalton Trans., pp. 4406-4415
Mineo, P., Vitalini, D., La Mendola, D., Rizzarelli, E., Scamporrino, E., Vecchio, G., Coordination features of difunctionalized ß-cyclodextrins with carnosine: ESI-MS and spectroscopic investigations on 6A,6D-di-(ß-alanyl-L- histidine)-6A,6D-dideoxy-ß-cyclodextrin and 6A,6C-di-(ß-alanyl-L- histidine)-6A,6C-dideoxy-ß-cyclodextrin and their copper(II) complexes (2004) Journal of Inorganic Biochemistry, 98 (2), pp. 254-265. , DOI 10.1016/j.jinorgbio.2003.10.015
Grasso, G.I., Arena, G., Bellia, F., Maccarrone, G., Parrinello, M., Pietropaolo, A., Vecchio, G., Rizzarelli, E., Intramolecular weak interactions in the thermodynamic stereoselectivity of copper(II) complexes with carnosine-trehalose conjugates (2011) Chem. Eur. J., 17, pp. 9448-9455
Amorini, A.M., Bellia, F., Di Pietro, V., Giardina, B., La Mendola, D., Lazzarino, G., Sortino, S., Vecchio, G., Synthesis and antioxidant activity of new homocarnosine ß-cyclodextrin conjugates (2007) European Journal of Medicinal Chemistry, 42 (7), pp. 910-920. , DOI 10.1016/j.ejmech.2006.12.036, PII S0223523407000384
La Mendola, D., Sortino, S., Vecchio, G., Rizzarelli, E., Synthesis of new carnosine derivatives of ß-cyclodextrin and their hydroxyl radical scavenger ability (2002) Helvetica Chimica Acta, 85 (6), pp. 1633-1643. , DOI 10.1002/1522-2675(200206)85:6<1633::AID-HLCA1633> 3.0.CO
Bellia, F., Amorini, A.M., La Mendola, D., Vecchio, G., Tavazzi, B., Giardina, B., Di Pietro, V., Rizzarelli, E., New glycosidic derivatives of histidine-containing dipeptides with antioxidant properties and resistant to carnosinase activity (2008) European Journal of Medicinal Chemistry, 43 (2), pp. 373-380. , DOI 10.1016/j.ejmech.2007.03.038, PII S0223523407001936
Boldyrev, A., Bulygina, E., Leinsoo, T., Petrushanko, I., Tsubone, S., Abe, H., Protection of neuronal cells against reactive oxygen species by carnosine and related compounds (2004) Comparative Biochemistry and Physiology - B Biochemistry and Molecular Biology, 137 (1), pp. 81-88. , DOI 10.1016/j.cbpc.2003.10.008
Green, N.M., Avidin and streptavidin (1990) Methods in Enzymology, 184, pp. 51-67. , DOI 10.1016/0076-6879(90)84259-J
Wilchek, M., Bayer, E.A., The avidin-biotin complex in bioanalytical applications (1988) Anal. Biochem., 171, pp. 1-32
Lee, H.J., Pardridge, W.M., Drug targeting to the brain using avidin-biotin technology in the mouse (blood-brain barrier, monoclonal antibody, transferrin receptor, Alzheimer's disease) (2000) Journal of Drug Targeting, 8 (6), pp. 413-424
Nobs, L., Buchegger, F., Gurny, R., Allemann, E., Biodegradable nanoparticles for direct or two-step tumor immunotargeting (2006) Bioconjugate Chemistry, 17 (1), pp. 139-145. , DOI 10.1021/bc050137k
Pulkkinen, M., Pikkarainen, J., Wirth, T., Tarvainen, T., Haapa-Aho, V., Korhonen, H., Seppala, J., Jarvinen, K., Three-step tumor targeting of paclitaxel using biotinylated PLA-PEG nanoparticles and avidin-biotin technology: Formulation development and in vitro anticancer activity (2008) Eur. J. Pharm. Biopharm., 70, pp. 66-74
Asakura, R., Isobe, T., Kurokawa, K., Aizawa, H., Ohkubo, M., Tagging of avidin immobilized beads with biotinylated YAG: Ce3+ nanocrystal phosphor (2006) Anal Bioanal. Chem., 386, pp. 1641-1647
Magnani, M., Chiarantini, L., Vittoria, E., Mancini, U., Rossi, L., Fazi, A., Red blood cells as an antigen-delivery system (1992) Biotechnol. Appl. Biochem., 16, pp. 188-194
Durmus, Z., Kavas, H., Baykal, A., Sozeri, H., Alpsoy, L., Elik, S.Ü., Toprak, M.S., Synthesis and characterization of l-carnosine coated iron oxide nanoparticles (2011) J. Alloys Compd, 509, pp. 2555-2561
Saada, M.C., Montero, J.L., Vullo, D., Scozzafava, A., Winum, J.Y., Supuran, C.T., Carbonic anhydrase activators: Gold nanoparticles coated with derivatized histamine, histidine, and carnosine show enhanced activatory effects on several mammalian isoforms (2011) J. Med. Chem., 54, pp. 1170-1177
Krpetic, Z., Guerrini, L., Larmour, I.A., Reglinski, J., Faulds, K., Graham, D., Importance of nanoparticle size in colorimetric and SERS-based multimodal trace detection of Ni(II) ions with functional gold nanoparticles (2012) Small, 8, pp. 707-714
Flaschka, H.A., (1959) EDTA Titrations: An Introduction to Theory and Practice, , Pergamon Press
Gran, G., Determination of the equivalence point in potentiometric titrations (1952) Analyst, 77, pp. 661-671
Gans, P., Sabatini, A., Vacca, A., SUPERQUAD: An improved general program for computation of formation constants from potentiometric data (1985) J. Chem. Soc. Dalton Trans., pp. 1195-1200
Bellia, F., Pietropaolo, A., Grasso, G., Formation of insulin fragments by insulin-degrading enzyme: The role of zinc(II) and cystine bridges (2013) J. Mass Spectrom., 48, pp. 135-140
Lanza, V., Bellia, F., D'Agata, R., Grasso, G., Rizzarelli, E., Vecchio, G., New glycoside derivatives of carnosine and analogs resistant to carnosinase hydrolysis: Synthesis and characterization of their copper(II) complexes (2011) J. Inorg. Biochem., 105, pp. 181-188
Janolino, V.G., Fontecha, J., Swaisgood, H.E., A spectrophotometric assay for biotin-binding sites of immobilized avidin (1996) Applied Biochemistry and Biotechnology - Part A Enzyme Engineering and Biotechnology, 56 (1), pp. 1-7
Oliveri, V., D'Agata, R., Giglio, V., Spoto, G., Vecchio, G., Cyclodextrin-functionalised gold nanoparticles via streptavidin: A supramolecular approach (2013) Supramol. Chem., 25, pp. 465-473
Lavanant, H., Virelizier, H., Hoppilliard, Y., Reduction of copper(II) complexes by electron capture in an electrospray ionization source (1998) J. Am. Soc. Mass. Spectrom., 9, pp. 1217-1221
Hofstetter, H., Morpurgo, M., Hofstetter, O., Bayer, E.A., Wilchek, M., A labeling, detection, and purification system based on 4-hydroxyazobenzene-2-carboxylic acid: An extension of the avidin-biotin system (2000) Anal. Biochem., 284, pp. 354-366
Kaur, K., Forrest, J.A., Influence of particle size on the binding activity of proteins adsorbed onto gold nanoparticles (2012) Langmuir, 28, pp. 2736-2744
Mohanraj, V.J., Chen, Y., Nanoparticles - A review (2006) Trop. J. Pharm. Res., 5, pp. 561-573
Jiang, W., Kim, B.Y.S., Rutka, J.T., Chan, W.C.W., Nanoparticle-mediated cellular response is size-dependent (2008) Nature Nanotechnology, 3 (3), pp. 145-150. , DOI 10.1038/nnano.2008.30, PII NNANO200830
Burda, C., Chen, X., Narayanan, R., El-Sayed, M.A., Chemistry and properties of nanocrystals of different shapes (2005) Chemical Reviews, 105 (4), pp. 1025-1102. , DOI 10.1021/cr030063a
Eur J Med Chem (ISSN: 1768-3254, 0223-5234, 1768-3254electronic), 2013 Dec; 70: 225-232.
Export to BibTeX Export to EndNote
Paper type: Journal Article, Research Support, Non-U. S. Gov'T,
Impact factor: 3.432, 5-year impact factor: 4.071
Url: http://www.scopus.com/inward/record.url?eid=2-s2.0-84886036303&partnerID=40&md5=6d10707b8b41c4de81d329c5c54bf92d
Keywords: Biotin, Carnosinase, Copper, Nanoparticles, Avidin Chemistry, Biotin Chemistry, Carnosine Chemical Synthesis Chemistry, Dipeptidases Blood Metabolism, Gold Chemistry, Humans, Metal Nanoparticles Chemistry, Molecular Structure, Spectrophotometry, Ultraviolet, Streptavidin Chemistry, Bio Nhs, Cupric Ion, Gold Nanoparticle, Unclassified Drug, Binding Assay, Drug Bioavailability, Drug Synthesis, Mass Spectrometry, Proton Nuclear Magnetic Resonance,
Affiliations:
*** IBB - CNR ***
Institute of Biostructure and Bioimaging, CNR, viale A. Doria 6, 95125 Catania, Italy. Electronic address: fbellia@unict.it.
Department of Chemical Sciences, University of Catania, viale A. Doria 6, 95125 Catania, Italy
References:
Gulewitsch, W., Amiradzibi, S., Carnosine, a new organic base from meat extracts (1900) Ber. Dtsch. Chem. Ges., 33, pp. 1902-190
Quinn, P.J., Boldyrev, A.A., Formazuyk, V.E., Carnosine: Its properties, functions and potential therapeutic applications (1992) Molecular Aspects of Medicine, 13 (5), pp. 379-444. , DOI 10.1016/0098-2997(92)90006-L
Decker, E.A., Livisay, S.A., Zhou, S., A re-evaluation of the antioxidant activity of purified carnosine (2000) Biochemistry (Moscow), 65, pp. 766-770
Kang, J.H., Kim, K.S., Choi, S.Y., Kwon, H.Y., Won, M.H., Kang, T.-C., Carnosine and related dipeptides protect human ceruloplasmin against peroxyl radical-mediated modification (2002) Molecules and Cells, 13 (3), pp. 498-502
Di Paola, R., Impellizzeri, D., Salinaro, A.T., Mazzon, E., Bellia, F., Cavallaro, M., Cornelius, C., Cuzzocrea, S., Administration of carnosine in the treatment of acute spinal cord injury (2011) Biochem. Pharmacol., 82, pp. 1478-1489
Renner, C., Zemitzsch, N., Fuchs, B., Geiger, K.D., Hermes, M., Hengstler, J., Gebhardt, R., Gaunitz, F., Carnosine retards tumor growth in vivo in an NIH3T3-HER2/neu mouse model (2010) Mol. Cancer, 9, p. 2
Ozel Turkcu, U., Bilgihan, A., Biberoglu, G., Mertoglu Caglar, O., Carnosine supplementation protects rat brain tissue against ethanol-induced oxidative stress (2010) Mol. Cell. Biochem., 339, pp. 55-61
Liu, W.H., Liu, T.C., Yin, M.C., Beneficial effects of histidine and carnosine on ethanol-induced chronic liver injury (2008) Food Chem. Toxicol., 46, pp. 1503-1509
Bellia, F., Vecchio, G., Cuzzocrea, S., Calabrese, V., Rizzarelli, E., Neuroprotective features of carnosine in oxidative driven diseases (2011) Mol. Aspects Med., 32, pp. 258-266
Hipkiss, A.R., Carnosine and its possible roles in nutrition and health (2009) Adv. Food Nutr. Res., 57, pp. 87-154
Teufel, M., Saudek, V., Ledig, J.-P., Bernhardt, A., Boularand, S., Carreau, A., Cairns, N.J., Smirnova, T., Sequence identification and characterization of human carnosinase and a closely related non-specific dipeptidase (2003) Journal of Biological Chemistry, 278 (8), pp. 6521-6531. , DOI 10.1074/jbc.M209764200
Bellia, F., Calabrese, V., Guarino, F., Cavallaro, M., Cornelius, C., De Pinto, V., Rizzarelli, E., Carnosinase levels in aging brain: Redox state induction and cellular stress response (2009) Antioxid. Redox Signal, 11, pp. 2759-2775
Lenney, J.F., Peppers, S.C., Kucera-Orallo, C.M., George, R.P., Characterization of human tissue carnosinase (1985) Biochemical Journal, 228 (3), pp. 653-660
Otani, H., Okumura, N., Hashida-Okumura, A., Nagai, K., Identification and characterization of a mouse dipeptidase that hydrolyzes l-carnosine (2005) J. Biochem. (Tokyo), 137, pp. 167-175
Bonomo, R.P., Bruno, V., Conte, E., De Guidi, G., La Mendola, D., Maccarrone, G., Nicoletti, F., Vecchio, G., Potentiometric, spectroscopic and antioxidant activity studies of SOD mimics containing carnosine (2003) Dalton Trans., pp. 4406-4415
Mineo, P., Vitalini, D., La Mendola, D., Rizzarelli, E., Scamporrino, E., Vecchio, G., Coordination features of difunctionalized ß-cyclodextrins with carnosine: ESI-MS and spectroscopic investigations on 6A,6D-di-(ß-alanyl-L- histidine)-6A,6D-dideoxy-ß-cyclodextrin and 6A,6C-di-(ß-alanyl-L- histidine)-6A,6C-dideoxy-ß-cyclodextrin and their copper(II) complexes (2004) Journal of Inorganic Biochemistry, 98 (2), pp. 254-265. , DOI 10.1016/j.jinorgbio.2003.10.015
Grasso, G.I., Arena, G., Bellia, F., Maccarrone, G., Parrinello, M., Pietropaolo, A., Vecchio, G., Rizzarelli, E., Intramolecular weak interactions in the thermodynamic stereoselectivity of copper(II) complexes with carnosine-trehalose conjugates (2011) Chem. Eur. J., 17, pp. 9448-9455
Amorini, A.M., Bellia, F., Di Pietro, V., Giardina, B., La Mendola, D., Lazzarino, G., Sortino, S., Vecchio, G., Synthesis and antioxidant activity of new homocarnosine ß-cyclodextrin conjugates (2007) European Journal of Medicinal Chemistry, 42 (7), pp. 910-920. , DOI 10.1016/j.ejmech.2006.12.036, PII S0223523407000384
La Mendola, D., Sortino, S., Vecchio, G., Rizzarelli, E., Synthesis of new carnosine derivatives of ß-cyclodextrin and their hydroxyl radical scavenger ability (2002) Helvetica Chimica Acta, 85 (6), pp. 1633-1643. , DOI 10.1002/1522-2675(200206)85:6<1633::AID-HLCA1633> 3.0.CO
Bellia, F., Amorini, A.M., La Mendola, D., Vecchio, G., Tavazzi, B., Giardina, B., Di Pietro, V., Rizzarelli, E., New glycosidic derivatives of histidine-containing dipeptides with antioxidant properties and resistant to carnosinase activity (2008) European Journal of Medicinal Chemistry, 43 (2), pp. 373-380. , DOI 10.1016/j.ejmech.2007.03.038, PII S0223523407001936
Boldyrev, A., Bulygina, E., Leinsoo, T., Petrushanko, I., Tsubone, S., Abe, H., Protection of neuronal cells against reactive oxygen species by carnosine and related compounds (2004) Comparative Biochemistry and Physiology - B Biochemistry and Molecular Biology, 137 (1), pp. 81-88. , DOI 10.1016/j.cbpc.2003.10.008
Green, N.M., Avidin and streptavidin (1990) Methods in Enzymology, 184, pp. 51-67. , DOI 10.1016/0076-6879(90)84259-J
Wilchek, M., Bayer, E.A., The avidin-biotin complex in bioanalytical applications (1988) Anal. Biochem., 171, pp. 1-32
Lee, H.J., Pardridge, W.M., Drug targeting to the brain using avidin-biotin technology in the mouse (blood-brain barrier, monoclonal antibody, transferrin receptor, Alzheimer's disease) (2000) Journal of Drug Targeting, 8 (6), pp. 413-424
Nobs, L., Buchegger, F., Gurny, R., Allemann, E., Biodegradable nanoparticles for direct or two-step tumor immunotargeting (2006) Bioconjugate Chemistry, 17 (1), pp. 139-145. , DOI 10.1021/bc050137k
Pulkkinen, M., Pikkarainen, J., Wirth, T., Tarvainen, T., Haapa-Aho, V., Korhonen, H., Seppala, J., Jarvinen, K., Three-step tumor targeting of paclitaxel using biotinylated PLA-PEG nanoparticles and avidin-biotin technology: Formulation development and in vitro anticancer activity (2008) Eur. J. Pharm. Biopharm., 70, pp. 66-74
Asakura, R., Isobe, T., Kurokawa, K., Aizawa, H., Ohkubo, M., Tagging of avidin immobilized beads with biotinylated YAG: Ce3+ nanocrystal phosphor (2006) Anal Bioanal. Chem., 386, pp. 1641-1647
Magnani, M., Chiarantini, L., Vittoria, E., Mancini, U., Rossi, L., Fazi, A., Red blood cells as an antigen-delivery system (1992) Biotechnol. Appl. Biochem., 16, pp. 188-194
Durmus, Z., Kavas, H., Baykal, A., Sozeri, H., Alpsoy, L., Elik, S.Ü., Toprak, M.S., Synthesis and characterization of l-carnosine coated iron oxide nanoparticles (2011) J. Alloys Compd, 509, pp. 2555-2561
Saada, M.C., Montero, J.L., Vullo, D., Scozzafava, A., Winum, J.Y., Supuran, C.T., Carbonic anhydrase activators: Gold nanoparticles coated with derivatized histamine, histidine, and carnosine show enhanced activatory effects on several mammalian isoforms (2011) J. Med. Chem., 54, pp. 1170-1177
Krpetic, Z., Guerrini, L., Larmour, I.A., Reglinski, J., Faulds, K., Graham, D., Importance of nanoparticle size in colorimetric and SERS-based multimodal trace detection of Ni(II) ions with functional gold nanoparticles (2012) Small, 8, pp. 707-714
Flaschka, H.A., (1959) EDTA Titrations: An Introduction to Theory and Practice, , Pergamon Press
Gran, G., Determination of the equivalence point in potentiometric titrations (1952) Analyst, 77, pp. 661-671
Gans, P., Sabatini, A., Vacca, A., SUPERQUAD: An improved general program for computation of formation constants from potentiometric data (1985) J. Chem. Soc. Dalton Trans., pp. 1195-1200
Bellia, F., Pietropaolo, A., Grasso, G., Formation of insulin fragments by insulin-degrading enzyme: The role of zinc(II) and cystine bridges (2013) J. Mass Spectrom., 48, pp. 135-140
Lanza, V., Bellia, F., D'Agata, R., Grasso, G., Rizzarelli, E., Vecchio, G., New glycoside derivatives of carnosine and analogs resistant to carnosinase hydrolysis: Synthesis and characterization of their copper(II) complexes (2011) J. Inorg. Biochem., 105, pp. 181-188
Janolino, V.G., Fontecha, J., Swaisgood, H.E., A spectrophotometric assay for biotin-binding sites of immobilized avidin (1996) Applied Biochemistry and Biotechnology - Part A Enzyme Engineering and Biotechnology, 56 (1), pp. 1-7
Oliveri, V., D'Agata, R., Giglio, V., Spoto, G., Vecchio, G., Cyclodextrin-functionalised gold nanoparticles via streptavidin: A supramolecular approach (2013) Supramol. Chem., 25, pp. 465-473
Lavanant, H., Virelizier, H., Hoppilliard, Y., Reduction of copper(II) complexes by electron capture in an electrospray ionization source (1998) J. Am. Soc. Mass. Spectrom., 9, pp. 1217-1221
Hofstetter, H., Morpurgo, M., Hofstetter, O., Bayer, E.A., Wilchek, M., A labeling, detection, and purification system based on 4-hydroxyazobenzene-2-carboxylic acid: An extension of the avidin-biotin system (2000) Anal. Biochem., 284, pp. 354-366
Kaur, K., Forrest, J.A., Influence of particle size on the binding activity of proteins adsorbed onto gold nanoparticles (2012) Langmuir, 28, pp. 2736-2744
Mohanraj, V.J., Chen, Y., Nanoparticles - A review (2006) Trop. J. Pharm. Res., 5, pp. 561-573
Jiang, W., Kim, B.Y.S., Rutka, J.T., Chan, W.C.W., Nanoparticle-mediated cellular response is size-dependent (2008) Nature Nanotechnology, 3 (3), pp. 145-150. , DOI 10.1038/nnano.2008.30, PII NNANO200830
Burda, C., Chen, X., Narayanan, R., El-Sayed, M.A., Chemistry and properties of nanocrystals of different shapes (2005) Chemical Reviews, 105 (4), pp. 1025-1102. , DOI 10.1021/cr030063a
New derivative of carnosine for nanoparticle assemblies
Carnosine (beta-alanyl-l-histidine) is an endogenous dipeptide, extensively studied owing to its multifunctional activity exhibited in tissues of several animal species. This natural compound may act as a physiological buffer, ion-chelating agent (especially for copper(II) and zinc(II)), antioxidant and antiglycating agent. The main limit for the therapeutical uses of carnosine is the rapid hydrolysis mostly in human plasma by carnosinase. The chemical derivatization of carnosine is a promising strategy to improve the bioavailability of the dipeptide and facilitating the site-specific transport to different tissues. On this basis, a new carnosine derivative with biotin was synthesized and structurally characterized by NMR and MS measurements, with aim of exploiting the avidin-biotin technology that offers a universal system for selective delivery of any biotinylated agent. The stability of the new carnosine derivative towards the hydrolytic action of serum carnosinase as well as the copper(II) binding ability of the carnosine-biotin conjugate were also assessed. The binding affinity of the new molecular entity to avidin and streptavidin, investigated by a spectrophotometric assay, was exploited to functionalize avidin- and streptavidin-gold nanoparticles with the carnosine-biotin conjugate. Copyright 2013 Elsevier Masson SAS. All rights reserved.
Carnosine (beta-alanyl-l-histidine) is an endogenous dipeptide, extensively studied owing to its multifunctional activity exhibited in tissues of several animal species. This natural compound may act as a physiological buffer, ion-chelating agent (especially for copper(II) and zinc(II)), antioxidant and antiglycating agent. The main limit for the therapeutical uses of carnosine is the rapid hydrolysis mostly in human plasma by carnosinase. The chemical derivatization of carnosine is a promising strategy to improve the bioavailability of the dipeptide and facilitating the site-specific transport to different tissues. On this basis, a new carnosine derivative with biotin was synthesized and structurally characterized by NMR and MS measurements, with aim of exploiting the avidin-biotin technology that offers a universal system for selective delivery of any biotinylated agent. The stability of the new carnosine derivative towards the hydrolytic action of serum carnosinase as well as the copper(II) binding ability of the carnosine-biotin conjugate were also assessed. The binding affinity of the new molecular entity to avidin and streptavidin, investigated by a spectrophotometric assay, was exploited to functionalize avidin- and streptavidin-gold nanoparticles with the carnosine-biotin conjugate. Copyright 2013 Elsevier Masson SAS. All rights reserved.
New derivative of carnosine for nanoparticle assemblies
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New derivative of carnosine for nanoparticle assemblies
Other filter: ([btitle,keywords] "Carnosinase" OR [bti ...
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* Curcumin-Loaded Nanoparticles Based on Amphiphilic Hyaluronan-Conjugate Explored as Targeting Delivery System for Neurodegenerative Disorders (59 views)
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Impact Factor: 4.556
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Siciliano G, Corricelli M, Iacobazzi RM, Canepa F, Comegna D, Fanizza E, Del Gatto A, Saviano M, Laquintana V, Comparelli R, Mascolo G, Murgolo S, Striccoli M, Agostiano A, Denora N, Zaccaro L, Curri ML, Depalo N
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Impact Factor: 4.857
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Conte C, Moret F, Esposito D, Dal Poggetto G, Avitabile C, Ungaro F, Romanelli A, Laurienzo P, Reddi E, Quaglia F
* Biodegradable nanoparticles exposing a short anti-FLT1 peptide as antiangiogenic platform to complement docetaxel anticancer activity (214 views)
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Impact Factor: 5.08
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Guryanov I, Real-fernandez F, Sabatino G, Prisco N, Korzhikov-vlakh V, Biondi B, Papini AM, Korzhikova-vlakh E, Rovero P, Tennikova T
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Impact Factor: 1.807
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Zambrano G, Ruggiero E, Malafronte A, Chino M, Maglio O, Pavone V, Nastri F, Lombardi A
* Artificial Heme Enzymes for the Construction of Gold-Based Biomaterials (241 views)
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Impact Factor: 3.687
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Venuta A, Moret F, Dal Poggetto G, Esposito D, Fraix A, Avitabile C, Ungaro F, Malinconico M, Sortino S, Romanelli A, Laurienzo P, Reddi E, Quaglia F
* Shedding light on surface exposition of poly(ethylene glycol) and folate targeting units on nanoparticles of poly(ε-caprolactone) diblock copolymers: Beyond a paradigm (549 views)
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Impact Factor: 0
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Satriano C, Munzone A, Cucci LM, Giacomelli C, Trincavelli ML, Martini C, Rizzarelli E, La Mendola D
* Angiogenin-mimetic peptide functionalised gold nanoparticles for cancer therapy applications (166 views)
Microchemical Journal (ISSN: 0026-265x), 2018; 136: 157-163.
Impact Factor: 2.579
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Oliveri V, Bellia F, Viale M, Maric I, Vecchio G
* Linear polymers of beta and gamma cyclodextrins with a polyglutamic acid backbone as carriers for doxorubicin (464 views)
Carbohyd Polym (ISSN: 0144-8617), 2017 Dec 1; 177: 355-360.
Impact Factor: 5.158
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Torino E, Auletta L, Vecchione D, Orlandella FM, Salvatore G, Iaccino E, Fiorenza D, Grimaldi AM, Sandomenico A, Albanese S, Sarnataro D, Gramanzini M, Palmieri C, Scala G, Quinto I, Netti PA, Salvatore M, Greco A
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Nanomedicine (ISSN: 1549-9634, 1549-9642), 2017 Nov 22; 14(2): 483-491.
Impact Factor: 6.5
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Crich SG, Terreno E, Aime S
* Nano-sized and other improved reporters for magnetic resonance imaging of angiogenesis (252 views)
Adv Drug Deliver Rev (ISSN: 0169-409x), 2017 Sep 15; 119: 61-72.
Impact Factor: 13.66
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Monaco I, Arena F, Biffi S, Locatelli E, Bortot B, La Cava F, Marini GM, Severini GM, Terreno E, Comes Franchini M
* Synthesis of Lipophilic Core-Shell Fe3O4@SiO2@Au Nanoparticles and Polymeric Entrapment into Nanomicelles: A Novel Nanosystem for in Vivo Active Targeting and Magnetic Resonance-Photoacoustic Dual Imaging (371 views)
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Impact Factor: 4.485
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Oliveri V, Bellia F, Vecchio G
* Cyclodextrin Nanoparticles Bearing 8-Hydroxyquinoline Ligands as Multifunctional Biomaterials (752 views)
Chemistry (ISSN: 0947-6539, 1521-3765, 1521-3765electronic), 2017; 23(18): 4442-4449.
Impact Factor: 5.16
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Longo DL, Stefania R, Callari C, De Rose F, Rolle R, Conti L, Consolino L, Arena F, Aime S
* Water Soluble Melanin Derivatives for Dynamic Contrast Enhanced Photoacoustic Imaging of Tumor Vasculature and Response to Antiangiogenic Therapy (229 views)
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Impact Factor: 5.11
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Gargiulo S, Gramanzini M, Mancini M
* Molecular Imaging of Vulnerable Atherosclerotic Plaques in Animal Models (373 views) (PDF 187 views)
Int J Mol Sc (ISSN: 1422-0067, 1661-6596, 1422-0067linking), 2016 Sep 9; 17(9): N/D-N/D.
Impact Factor: 3.226
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Di Pietro P, Zaccaro L, Comegna D, Del Gatto A, Saviano M, Snyders R, Cossement D, Satriano C, Rizzarelli E
* Silver nanoparticles functionalized with a fluorescent cyclic RGD peptide: a versatile integrin targeting platform for cells and bacteria (311 views) (PDF 162 views)
The Royal Society Of Chemistry, 2016 Jan 01; 6: N/D-N/D.
Impact Factor: 3.564
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Accardo A, Arena F, Gianolio E, Marasco D, Ringhieri P, Boffa C, Bardini P, Aime S, Morelli G
* Diolein based nanostructures as targeted theranostics (446 views)
J Biomed Nanotechnol (ISSN: 1550-7033), 2016; 12(5): 1076-1088.
Impact Factor: 4.521
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Calce E, Ringhieri P, Mercurio FA, Leone M, Bugatti V, Saviano M, Vittoria V, De Luca S
* A biocompatible process to prepare hyaluronan-based material able to self-assemble into stable nano-particles (377 views)
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Impact Factor: 3.289
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Merlino A, Caterino M, Russo Krauss I, Vergara A
* Missing gold atoms in lysozyme crystals used to grow gold nanoparticles (310 views)
Nat Nanotechnol (ISSN: 1748-3387), 2015; 10(4): 285-285.
Impact Factor: 35.267
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Galdiero S, Falanga A, Vitiello M, Grieco P, Caraglia M, Morelli G, Galdiero M
* Exploitation of viral properties for intracellular delivery (508 views)
J Pept Sci (ISSN: 1075-2617, 1099-1387, 1075-2617linking), 2014 Jul; 20(7): 468-478.
Impact Factor: 1.546
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Accardo A, Ringhieri P, Szekely N, Pipich V, Luchini A, Paduano L, Tesauro D
* Structural insights on nanoparticles containing gadolinium complexes as potential theranostic (454 views)
Colloid Polym Sci (ISSN: 0303-402x), 2014 May; 292(5): 1121-1127.
Impact Factor: 1.865
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Accardo A, Aloj L, Aurilio M, Morelli G, Tesauro D
* Receptor binding peptides for target-selective delivery of nanoparticles encapsulated drugs (571 views)
Int J Nanomed (ISSN: 1178-2013, 1176-9114, 1176-9114linking), 2014 Mar 27; 9(1): 1537-1557.
Impact Factor: 4.383
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Rai M, Kon K, Ingle A, Duran N, Galdiero S, Galdiero M
* Broad-spectrum bioactivities of silver nanoparticles: the emerging trends and future prospects (727 views)
Appl Microbiol Biot (ISSN: 0175-7598), 2014 Mar; 98(5): 1951-1961.
Impact Factor: 3.337
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Bellia F, Vecchio G, Rizzarelli E
* Carnosinases, Their Substrates And Diseases (660 views)
Molecules (ISSN: 1420-3049, 1420-3049electronic, 1420-3049linking), 2014 Feb 21; 19(2): 2299-2329.
Impact Factor: 2.416
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Grasso GI, Arena G, Bellia F, Rizzarelli E, Vecchio G
* Copper(II)-chelating homocarnosine glycoconjugate as a new multifunctional compound (560 views)
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Impact Factor: 3.444
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Bellia F, Vecchio G, Rizzarelli E
* Carnosine and Cognitive Deficits (171 views)
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Impact Factor: 0
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Falciani C, Brunetti J, Lelli B, Accardo A, Tesauro D, Morelli G, Bracci L
* Nanoparticles exposing neurotensin tumor-specific drivers (448 views)
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Impact Factor: 1.862
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D'Agata R, Spoto G
* Surface plasmon resonance imaging for nucleic acid detection (360 views)
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Impact Factor: 3.578
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Travaglia A, Satriano C, Giuffrida ML, La Mendola D, Rampazzo E, Prodi L, Rizzarelli E
* Electrostatically driven interaction of silica-supported lipid bilayer nanoplatforms and a nerve growth factor-mimicking peptide (338 views)
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Impact Factor: 4.151
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Bellia F, Vecchio G, Rizzarelli E
* Carnosine derivatives: new multifunctional drug-like molecules (549 views)
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Impact Factor: 3.914
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Musumeci D, Oliviero G, Roviello GN, Bucci EM, Piccialli G
* G-quadruplex-forming oligonucleotide conjugated to magnetic nanoparticles: Synthesis, characterization, and enzymatic stability assays (754 views)
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Impact Factor: 4.58
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Scarí G, Porta F, Fascio U, Avvakumova S, Dal Santo V, De Simone M, Saviano M, Leone M, Del Gatto A, Pedone C, Zaccaro L
* Gold nanoparticles capped by a GC-containing peptide functionalized with an RGD motif for integrin targeting (561 views)
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Impact Factor: 4.58
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Zanoli LM, D'Agata R, Spoto G
* Functionalized gold nanoparticles for ultrasensitive DNA detection (341 views)
Anal Bioanal Chem (ISSN: 1618-2642), 2012 Feb; 402(5): 1759-1771.
Impact Factor: 3.659
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Rampazzo E, Bonacchi S, Genovese D, Juris R, Sgarzi M, Montalti M, Prodi L, Zaccheroni N, Tomaselli G, Gentile S, Satriano C, Rizzarelli E
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Impact Factor: 5.925
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Galdiero S, Falanga A, Vitiello M, Cantisani M, Marra V, Galdiero M
* Silver Nanoparticles as Potential Antiviral Agents (759 views)
Molecules (ISSN: 1420-3049, 1420-3049electronic, 1420-3049linking), 2011 Oct; 16(10): 8894-8918.
Impact Factor: 2.386
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Bellia F, Vecchio G, Cuzzocrea S, Calabrese V, Rizzarelli E
* Neuroprotective features of carnosine in oxidative driven diseases (424 views)
Molecular Aspects Of Medicine (ISSN: 1872-9452, 0098-2997), 2011 Sep; 32(4-6): 258-266.
Impact Factor: 9.97
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Malvindi MA, Greco A, Conversano F, Figuerola A, Corti M, Bonora M, Lascialfari A, Doumari HA, Moscardini M, Cingolani R, Gigli G, Casciaro S, Pellegrino T, Ragusa A
* MR Contrast Agents (292 views)
Small Animal Imaging, 2011 Jul 8; 21(13): 2548-2555.
Impact Factor: 1.784
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Accardo A, Morisco A, Gianolio E, Tesauro D, Mangiapia G, Radulescu A, Brandt A, Morelli G
* Nanoparticles containing octreotide peptides and gadolinium complexes for MRI applications (504 views)
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Impact Factor: 1.799
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Accardo A, Morisco A, Tesauro D, Pedone C, Morelli G
* Naposomes: A new class of peptide-derivatized, target-selective multimodal nanoparticles for imaging and therapeutic applications (408 views)
Ther Deliv (ISSN: 2041-5990), 2011 Feb; 2(2): 235-257.
Impact Factor: 0
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Lanza V, Bellia F, D'Agata R, Grasso G, Rizzarelli E, Vecchio G
* New glycoside derivatives of carnosine and analogs resistant to carnosinase hydrolysis: synthesis and characterization of their copper(II) complexes (402 views)
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Impact Factor: 3.354
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Casciaro S, Conversano F, Ragusa A, Malvindi MA, Franchini R, Greco A, Pellegrino T, Gigli G
* Optimal enhancement configuration of silica nanoparticles for ultrasound imaging and automatic detection at conventional diagnostic frequencies (402 views)
Invest Radiol (ISSN: 0020-9996, 1536-0210, 1536-0210electronic), 2010 Nov; 45(11): 715-724.
Impact Factor: 4.67
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Mainenti PP, Mancini M, Mainolfi C, Camera L, Maurea S, Manchia A, Tanga M, Persico F, Addeo P, D'Antonio D, Speranza A, Bucci L, Persico G, Pace L, Salvatore M
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Impact Factor: 1.95
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D'Agata R, Corradini R, Ferretti C, Zanoli L, Gatti M, Marchelli R, Spoto G
* Ultrasensitive detection of non-amplified genomic DNA (414 views)
Lect Notes Electr Eng, 2010 May 15; 91LNEE: 485-488.
Impact Factor: 0
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D'Agata R, Corradini R, Ferretti C, Zanoli L, Gatti M, Marchelli R, Spoto G
* Ultrasensitive detection of non-amplified genomic DNA by nanoparticle-enhanced surface plasmon resonance imaging (422 views)
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Impact Factor: 5.361
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D'Urso L, Grasso G, Messina E, Bongiorno C, Scuderi V, Scalese S, Puglisi O, Spoto G, Compagnini G
* The Role of Linear Carbon Chains in the Aggregation of Copper, Silver, and Gold Nanoparticles (521 views)
J Phys Chem C (ISSN: 1932-7447), 2010 Jan 21; 114(2): 907-915.
Impact Factor: 4.524
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Bellia F, Calabrese V, Guarino F, Cavallaro M, Cornelius C, De Pinto V, Rizzarelli E
* Carnosinase levels in aging brain: redox state induction and cellular stress response (430 views)
Antioxid Redox Signal (ISSN: 1557-7716, 1523-0864, 1523-0864linking), 2009 Nov; 11(11): 2759-2775.
Impact Factor: 7.581
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Bellia F, Amorini AM, La Mendola D, Vecchio G, Tavazzi B, Giardina B, Di Pietro V, Lazzarino G, Rizzarelli E
* New glycosidic derivatives of histidine-containing dipeptides with antioxidant properties and resistant to carnosinase activity (444 views)
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Impact Factor: 2.882
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* Selective Photo-Assisted Eradication of Triple-Negative Breast Cancer Cells through Aptamer Decoration of Doped Conjugated Polymer Nanoparticles (12 views)
Pharmaceutics (ISSN: 1999-4923linking), 2022 Mar 12; 14(3): N/D-N/D.
Impact Factor: 6.321
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Caputo T, Cusano AM, Ruvo M, Aliberti A, Cusano A
* Human Serum Albumin Nanoparticles as a Carrier for On-Demand Sorafenib Delivery (18 views)
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Impact Factor: 2.097
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Baroni S, Stefania R, Broche LM, Senn N, Lurie DJ, Ross PJ, Aime S, Geninatti Crich S
* A Novel Class of (1) H-MRI Contrast Agents Based on the Relaxation Enhancement Induced on Water Protons by (14) N-Containing Imidazole Moieties (74 views)
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Impact Factor: 12.959
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Pepe G, Calce E, Verdoliva V, Saviano M, Maglione V, Di Pardo A, De Luca S
* Curcumin-Loaded Nanoparticles Based on Amphiphilic Hyaluronan-Conjugate Explored as Targeting Delivery System for Neurodegenerative Disorders (59 views)
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Impact Factor: 4.556
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Siciliano G, Corricelli M, Iacobazzi RM, Canepa F, Comegna D, Fanizza E, Del Gatto A, Saviano M, Laquintana V, Comparelli R, Mascolo G, Murgolo S, Striccoli M, Agostiano A, Denora N, Zaccaro L, Curri ML, Depalo N
* Gold-Speckled SPION@SiO(2) Nanoparticles Decorated with Thiocarbohydrates for ASGPR1 Targeting: Towards HCC Dual Mode Imaging Potential Applications (93 views)
Chemistry (ISSN: 0947-6539linking, 1521-3765electronic), 2020 Aug 26; 26(48): 11048-11059.
Impact Factor: 4.857
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Conte C, Moret F, Esposito D, Dal Poggetto G, Avitabile C, Ungaro F, Romanelli A, Laurienzo P, Reddi E, Quaglia F
* Biodegradable nanoparticles exposing a short anti-FLT1 peptide as antiangiogenic platform to complement docetaxel anticancer activity (214 views)
Mater Sci Eng C Mater Biol Appl (ISSN: 0928-4931linking), 2019 Sep; 102: 876-886.
Impact Factor: 5.08
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Guryanov I, Real-fernandez F, Sabatino G, Prisco N, Korzhikov-vlakh V, Biondi B, Papini AM, Korzhikova-vlakh E, Rovero P, Tennikova T
* Modeling interaction between gp120 HIV protein and CCR5 receptor (273 views)
J Pept Sci (ISSN: 1075-2617linking, 1099-1387electronic), 2019 Feb; 25 (2 ): e3142-e3142.
Impact Factor: 1.807
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Zambrano G, Ruggiero E, Malafronte A, Chino M, Maglio O, Pavone V, Nastri F, Lombardi A
* Artificial Heme Enzymes for the Construction of Gold-Based Biomaterials (241 views)
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Impact Factor: 3.687
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Venuta A, Moret F, Dal Poggetto G, Esposito D, Fraix A, Avitabile C, Ungaro F, Malinconico M, Sortino S, Romanelli A, Laurienzo P, Reddi E, Quaglia F
* Shedding light on surface exposition of poly(ethylene glycol) and folate targeting units on nanoparticles of poly(ε-caprolactone) diblock copolymers: Beyond a paradigm (549 views)
Eur J Pharm Sci (ISSN: 0928-0987, 0928-0987linking), 2018 Jan 1; 111: 177-185.
Impact Factor: 0
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Satriano C, Munzone A, Cucci LM, Giacomelli C, Trincavelli ML, Martini C, Rizzarelli E, La Mendola D
* Angiogenin-mimetic peptide functionalised gold nanoparticles for cancer therapy applications (166 views)
Microchemical Journal (ISSN: 0026-265x), 2018; 136: 157-163.
Impact Factor: 2.579
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Oliveri V, Bellia F, Viale M, Maric I, Vecchio G
* Linear polymers of beta and gamma cyclodextrins with a polyglutamic acid backbone as carriers for doxorubicin (464 views)
Carbohyd Polym (ISSN: 0144-8617), 2017 Dec 1; 177: 355-360.
Impact Factor: 5.158
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Torino E, Auletta L, Vecchione D, Orlandella FM, Salvatore G, Iaccino E, Fiorenza D, Grimaldi AM, Sandomenico A, Albanese S, Sarnataro D, Gramanzini M, Palmieri C, Scala G, Quinto I, Netti PA, Salvatore M, Greco A
* Multimodal imaging for a theranostic approach in a murine model of B-cell lymphoma with engineered nanoparticles (290 views) (PDF 163 views)
Nanomedicine (ISSN: 1549-9634, 1549-9642), 2017 Nov 22; 14(2): 483-491.
Impact Factor: 6.5
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Crich SG, Terreno E, Aime S
* Nano-sized and other improved reporters for magnetic resonance imaging of angiogenesis (252 views)
Adv Drug Deliver Rev (ISSN: 0169-409x), 2017 Sep 15; 119: 61-72.
Impact Factor: 13.66
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Monaco I, Arena F, Biffi S, Locatelli E, Bortot B, La Cava F, Marini GM, Severini GM, Terreno E, Comes Franchini M
* Synthesis of Lipophilic Core-Shell Fe3O4@SiO2@Au Nanoparticles and Polymeric Entrapment into Nanomicelles: A Novel Nanosystem for in Vivo Active Targeting and Magnetic Resonance-Photoacoustic Dual Imaging (371 views)
Bioconjug Chem (ISSN: 1043-1802, 1520-4812), 2017 May 17; 28(5): 1382-1390.
Impact Factor: 4.485
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Oliveri V, Bellia F, Vecchio G
* Cyclodextrin Nanoparticles Bearing 8-Hydroxyquinoline Ligands as Multifunctional Biomaterials (752 views)
Chemistry (ISSN: 0947-6539, 1521-3765, 1521-3765electronic), 2017; 23(18): 4442-4449.
Impact Factor: 5.16
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Longo DL, Stefania R, Callari C, De Rose F, Rolle R, Conti L, Consolino L, Arena F, Aime S
* Water Soluble Melanin Derivatives for Dynamic Contrast Enhanced Photoacoustic Imaging of Tumor Vasculature and Response to Antiangiogenic Therapy (229 views)
Adv Healthc Mater (ISSN: 2192-2640, 2192-2640linking), 2016 Oct 26; N/D: N/D-N/D.
Impact Factor: 5.11
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Gargiulo S, Gramanzini M, Mancini M
* Molecular Imaging of Vulnerable Atherosclerotic Plaques in Animal Models (373 views) (PDF 187 views)
Int J Mol Sc (ISSN: 1422-0067, 1661-6596, 1422-0067linking), 2016 Sep 9; 17(9): N/D-N/D.
Impact Factor: 3.226
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Di Pietro P, Zaccaro L, Comegna D, Del Gatto A, Saviano M, Snyders R, Cossement D, Satriano C, Rizzarelli E
* Silver nanoparticles functionalized with a fluorescent cyclic RGD peptide: a versatile integrin targeting platform for cells and bacteria (311 views) (PDF 162 views)
The Royal Society Of Chemistry, 2016 Jan 01; 6: N/D-N/D.
Impact Factor: 3.564
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Accardo A, Arena F, Gianolio E, Marasco D, Ringhieri P, Boffa C, Bardini P, Aime S, Morelli G
* Diolein based nanostructures as targeted theranostics (446 views)
J Biomed Nanotechnol (ISSN: 1550-7033), 2016; 12(5): 1076-1088.
Impact Factor: 4.521
View Export to BibTeX Export to EndNote
Calce E, Ringhieri P, Mercurio FA, Leone M, Bugatti V, Saviano M, Vittoria V, De Luca S
* A biocompatible process to prepare hyaluronan-based material able to self-assemble into stable nano-particles (377 views)
Rsc Adv (ISSN: 2046-2069), 2015; 5(37): 29573-29576.
Impact Factor: 3.289
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Merlino A, Caterino M, Russo Krauss I, Vergara A
* Missing gold atoms in lysozyme crystals used to grow gold nanoparticles (310 views)
Nat Nanotechnol (ISSN: 1748-3387), 2015; 10(4): 285-285.
Impact Factor: 35.267
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Galdiero S, Falanga A, Vitiello M, Grieco P, Caraglia M, Morelli G, Galdiero M
* Exploitation of viral properties for intracellular delivery (508 views)
J Pept Sci (ISSN: 1075-2617, 1099-1387, 1075-2617linking), 2014 Jul; 20(7): 468-478.
Impact Factor: 1.546
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Accardo A, Ringhieri P, Szekely N, Pipich V, Luchini A, Paduano L, Tesauro D
* Structural insights on nanoparticles containing gadolinium complexes as potential theranostic (454 views)
Colloid Polym Sci (ISSN: 0303-402x), 2014 May; 292(5): 1121-1127.
Impact Factor: 1.865
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Accardo A, Aloj L, Aurilio M, Morelli G, Tesauro D
* Receptor binding peptides for target-selective delivery of nanoparticles encapsulated drugs (571 views)
Int J Nanomed (ISSN: 1178-2013, 1176-9114, 1176-9114linking), 2014 Mar 27; 9(1): 1537-1557.
Impact Factor: 4.383
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Rai M, Kon K, Ingle A, Duran N, Galdiero S, Galdiero M
* Broad-spectrum bioactivities of silver nanoparticles: the emerging trends and future prospects (727 views)
Appl Microbiol Biot (ISSN: 0175-7598), 2014 Mar; 98(5): 1951-1961.
Impact Factor: 3.337
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Bellia F, Vecchio G, Rizzarelli E
* Carnosinases, Their Substrates And Diseases (660 views)
Molecules (ISSN: 1420-3049, 1420-3049electronic, 1420-3049linking), 2014 Feb 21; 19(2): 2299-2329.
Impact Factor: 2.416
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Grasso GI, Arena G, Bellia F, Rizzarelli E, Vecchio G
* Copper(II)-chelating homocarnosine glycoconjugate as a new multifunctional compound (560 views)
J Chem Res (ISSN: 0162-0134, 1873-3344, 0162-0134print), 2014 Feb; 131: 56-63.
Impact Factor: 3.444
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Bellia F, Vecchio G, Rizzarelli E
* Carnosine and Cognitive Deficits (171 views)
Diet And Nutr In Dement And Cogn Decline (ISSN: 9780-1240793979780124078246), 2014; N/D: 973-982.
Impact Factor: 0
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Falciani C, Brunetti J, Lelli B, Accardo A, Tesauro D, Morelli G, Bracci L
* Nanoparticles exposing neurotensin tumor-specific drivers (448 views)
J Pept Sci (ISSN: 1075-2617, 1099-1387, 1075-2617print), 2013 Apr; 19(4): 198-204.
Impact Factor: 1.862
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D'Agata R, Spoto G
* Surface plasmon resonance imaging for nucleic acid detection (360 views)
Anal Bioanal Chem (ISSN: 1618-2642), 2013 Jan; 405(2-3): 573-584.
Impact Factor: 3.578
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Travaglia A, Satriano C, Giuffrida ML, La Mendola D, Rampazzo E, Prodi L, Rizzarelli E
* Electrostatically driven interaction of silica-supported lipid bilayer nanoplatforms and a nerve growth factor-mimicking peptide (338 views)
Soft Matter (ISSN: 1744-683x), 2013; 9(18): 4648-4654.
Impact Factor: 4.151
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Bellia F, Vecchio G, Rizzarelli E
* Carnosine derivatives: new multifunctional drug-like molecules (549 views)
Amino Acids (ISSN: 1438-2199, 0939-4451, 1438-2199electronic), 2012 Jul; 43(1): 153-163.
Impact Factor: 3.914
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Musumeci D, Oliviero G, Roviello GN, Bucci EM, Piccialli G
* G-quadruplex-forming oligonucleotide conjugated to magnetic nanoparticles: Synthesis, characterization, and enzymatic stability assays (754 views)
Bioconjug Chem (ISSN: 1043-1802, 1520-4812, 1520-4812electronic), 2012 Mar 21; 23(3): 382-391.
Impact Factor: 4.58
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Scarí G, Porta F, Fascio U, Avvakumova S, Dal Santo V, De Simone M, Saviano M, Leone M, Del Gatto A, Pedone C, Zaccaro L
* Gold nanoparticles capped by a GC-containing peptide functionalized with an RGD motif for integrin targeting (561 views)
Bioconjug Chem (ISSN: 1520-4812, 1043-1802, 1520-4812electronic), 2012 Mar 21; 23(3): 340-349.
Impact Factor: 4.58
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Zanoli LM, D'Agata R, Spoto G
* Functionalized gold nanoparticles for ultrasensitive DNA detection (341 views)
Anal Bioanal Chem (ISSN: 1618-2642), 2012 Feb; 402(5): 1759-1771.
Impact Factor: 3.659
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Rampazzo E, Bonacchi S, Genovese D, Juris R, Sgarzi M, Montalti M, Prodi L, Zaccheroni N, Tomaselli G, Gentile S, Satriano C, Rizzarelli E
* A versatile strategy for signal amplification based on core/shell silica nanoparticles (444 views)
Chemistry (ISSN: 1521-3765, 0947-6539, 1521-3765electronic), 2011 Nov 25; 17(48): 13429-13432.
Impact Factor: 5.925
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Galdiero S, Falanga A, Vitiello M, Cantisani M, Marra V, Galdiero M
* Silver Nanoparticles as Potential Antiviral Agents (759 views)
Molecules (ISSN: 1420-3049, 1420-3049electronic, 1420-3049linking), 2011 Oct; 16(10): 8894-8918.
Impact Factor: 2.386
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Bellia F, Vecchio G, Cuzzocrea S, Calabrese V, Rizzarelli E
* Neuroprotective features of carnosine in oxidative driven diseases (424 views)
Molecular Aspects Of Medicine (ISSN: 1872-9452, 0098-2997), 2011 Sep; 32(4-6): 258-266.
Impact Factor: 9.97
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Malvindi MA, Greco A, Conversano F, Figuerola A, Corti M, Bonora M, Lascialfari A, Doumari HA, Moscardini M, Cingolani R, Gigli G, Casciaro S, Pellegrino T, Ragusa A
* MR Contrast Agents (292 views)
Small Animal Imaging, 2011 Jul 8; 21(13): 2548-2555.
Impact Factor: 1.784
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Accardo A, Morisco A, Gianolio E, Tesauro D, Mangiapia G, Radulescu A, Brandt A, Morelli G
* Nanoparticles containing octreotide peptides and gadolinium complexes for MRI applications (504 views)
J Pept Sci (ISSN: 1075-2617, 1099-1387, 1075-2617print), 2011 Feb; 17(2): 154-162.
Impact Factor: 1.799
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Accardo A, Morisco A, Tesauro D, Pedone C, Morelli G
* Naposomes: A new class of peptide-derivatized, target-selective multimodal nanoparticles for imaging and therapeutic applications (408 views)
Ther Deliv (ISSN: 2041-5990), 2011 Feb; 2(2): 235-257.
Impact Factor: 0
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Lanza V, Bellia F, D'Agata R, Grasso G, Rizzarelli E, Vecchio G
* New glycoside derivatives of carnosine and analogs resistant to carnosinase hydrolysis: synthesis and characterization of their copper(II) complexes (402 views)
J Chem Res (ISSN: 1873-3344, 0162-0134, 0162-0134print), 2011 Feb; 105(2): 181-188.
Impact Factor: 3.354
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Casciaro S, Conversano F, Ragusa A, Malvindi MA, Franchini R, Greco A, Pellegrino T, Gigli G
* Optimal enhancement configuration of silica nanoparticles for ultrasound imaging and automatic detection at conventional diagnostic frequencies (402 views)
Invest Radiol (ISSN: 0020-9996, 1536-0210, 1536-0210electronic), 2010 Nov; 45(11): 715-724.
Impact Factor: 4.67
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Mainenti PP, Mancini M, Mainolfi C, Camera L, Maurea S, Manchia A, Tanga M, Persico F, Addeo P, D'Antonio D, Speranza A, Bucci L, Persico G, Pace L, Salvatore M
* Detection of colo-rectal liver metastases: Prospective comparison of contrast enhanced US, multidetector CT, PET/CT, and 1. 5 Tesla MR with extracellular and reticulo-endothelial cell specific contrast agents (433 views)
Abdom Imaging (ISSN: 0942-8925, 1432-0509), 2010 Oct; 35(5): 511-521.
Impact Factor: 1.95
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D'Agata R, Corradini R, Ferretti C, Zanoli L, Gatti M, Marchelli R, Spoto G
* Ultrasensitive detection of non-amplified genomic DNA (414 views)
Lect Notes Electr Eng, 2010 May 15; 91LNEE: 485-488.
Impact Factor: 0
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D'Agata R, Corradini R, Ferretti C, Zanoli L, Gatti M, Marchelli R, Spoto G
* Ultrasensitive detection of non-amplified genomic DNA by nanoparticle-enhanced surface plasmon resonance imaging (422 views)
Biosens Bioelectron (ISSN: 0956-5663, 1873-4235electronic), 2010 May 15; 25(9): 2095-2100.
Impact Factor: 5.361
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D'Urso L, Grasso G, Messina E, Bongiorno C, Scuderi V, Scalese S, Puglisi O, Spoto G, Compagnini G
* The Role of Linear Carbon Chains in the Aggregation of Copper, Silver, and Gold Nanoparticles (521 views)
J Phys Chem C (ISSN: 1932-7447), 2010 Jan 21; 114(2): 907-915.
Impact Factor: 4.524
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Bellia F, Calabrese V, Guarino F, Cavallaro M, Cornelius C, De Pinto V, Rizzarelli E
* Carnosinase levels in aging brain: redox state induction and cellular stress response (430 views)
Antioxid Redox Signal (ISSN: 1557-7716, 1523-0864, 1523-0864linking), 2009 Nov; 11(11): 2759-2775.
Impact Factor: 7.581
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Bellia F, Amorini AM, La Mendola D, Vecchio G, Tavazzi B, Giardina B, Di Pietro V, Lazzarino G, Rizzarelli E
* New glycosidic derivatives of histidine-containing dipeptides with antioxidant properties and resistant to carnosinase activity (444 views)
Eur J Med Chem (ISSN: 0223-5234, 1768-3254, 1768-3254electronic), 2008 Feb; 43(2): 373-380.
Impact Factor: 2.882
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49 Records (49 excluding Abstracts).
Total impact factor: 229.384 (229.384 excluding Abstracts).
Total 5 year impact factor: 218.465 (218.465 excluding Abstracts).
Total impact factor: 229.384 (229.384 excluding Abstracts).
Total 5 year impact factor: 218.465 (218.465 excluding Abstracts).
458 views. Last view on Friday 24 March 2023, 17:45:39
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