Multiple sclerosis: cerebral circulation time (419 views)
Radiology (ISSN: 1527-1315, 0033-8419, 1527-1315electronic), 2012 Mar; 262(3): 947-955.
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Paper type: Journal Article,
Impact factor: 6.339, 5-year impact factor: 6.738
Url: http://www.scopus.com/inward/record.url?eid=2-s2.0-84858726157&partnerID=40&md5=b27d855a7648b1d9798c6380fea20e47
Keywords: Sonovue, Adult, Article, Brain Blood Flow, Carotid Artery, Cerebral Circulation Time, Chronic Cerebrospinal Venous Insufficiency, Color Ultrasound Flowmetry, Contrast Enhancement, Controlled Study, Disease Association, Drug Tolerability, Extracranial Venous Outflow, Female, Headache, Hot Flush, Human, Internal Jugular Vein, Intracranial Venous Outflow, Major Clinical Study, Multiple Sclerosis, Priority Journal, Prospective Study, Vascular Disease, Venous Reflux, Aged, Analysis Of Variance, Case-Control Studies, Cerebrovascular Circulation, Chi-Square Distribution, Contrast Media, Electrocardiography, Middle Aged, Phospholipids, Prospective Studies, Statistics, Nonparametric, Sulfur Hexafluoride, Ultrasonography, Doppler, Transcranial,
Affiliations:
*** IBB - CNR ***
Institute of Biostructure and Bioimaging, National Research Council of Italy, Federico II University School of Medicine, Via Pansini 5, Edificio 10, 80131 Naples, Italy. marcello.mancini@libero.it
Department of Neurologic Sciences, Federico II University School of Medicine, Edificio 10, 80131 Naples, Italy
Department of Biomorphological and Functional Science, Federico II University School of Medicine, Edificio 10, Via Pansini 5, 80131 Naples, Italy
SDN Foundation, Institute of Diagnostic and Nuclear Development, Naples, Italy
Hermitage Capodimonte IDC, Naples, Italy
References:
Lucchinetti, C., Bruck, W., Parisi, J., Scheithauer, B., Rodriguez, M., Lassmann, H., Heterogeneity of multiple sclerosis lesions: Implications for the pathogenesis of demyelination (2000) Annals of Neurology, 47 (6), pp. 707-717. , DOI 10.1002/1531-8249(200006)47:6<707::AID-ANA3> 3.0.CO
Lassmann, H., Hypoxia-like tissue injury as a component of multiple sclerosis lesions (2003) Journal of the Neurological Sciences, 206 (2), pp. 187-191. , DOI 10.1016/S0022-510X(02)00421-5, PII S0022510X02004215
Ge, Y., Law, M., Johnson, G., Herbert, J., Babb, J.S., Mannon, L.J., Grossman, R.I., Dynamic susceptibility contrast perfusion MR imaging of multiple sclerosis lesions: Characterizing hemodynamic impairment and inflammatory activity (2005) American Journal of Neuroradiology, 26 (6), pp. 1539-1547
Qiu, W., Raven, S., Wu, J.S., Carroll, W.M., Mastaglia, F.L., Kermode, A.G., Wedge-shaped medullary lesions in multiple sclerosis (2010) J Neurol Sci, 290 (1-2), pp. 190-193
Putnam, T.J., Evidences of vascular occlusion in multiple sclerosis and "encephalomyelitis" (1937) Arch Neurol Psychiatry, 37 (6), pp. 1298-1321
Zamboni, P., Galeotti, R., Menegatti, E., Chronic cerebrospinal venous insufficiency in patients with multiple sclerosis (2009) J Neurol Neurosurg Psychiatry, 80 (4), pp. 392-399
Zamboni, P., Menegatti, E., Galeotti, R., The value of cerebral Doppler venous haemodynamics in the assessment of multiple sclerosis (2009) J Neurol Sci, 282 (1-2), pp. 21-27
Doepp, F., Paul, F., Valdueza, J.M., Schmierer, K., Schreiber, S.J., No cerebrocervical venous congestion in patients with multiple sclerosis (2010) Ann Neurol, 68 (2), pp. 173-183
Sundström, P., Wåhlin, A., Ambarki, K., Birgander, R., Eklund, A., Malm, J., Venous and cerebrospinal fluid flow in multiple sclerosis: A case-control study (2010) Ann Neurol, 68 (2), pp. 255-259
Wattjes, M.P., Van Oosten, B.W., De Graaf, W.L., No association of abnormal cranial venous drainage with multiple sclerosis: A magnetic resonance venography and flow-quantification study (2011) J Neurol Neurosurg Psychiatry, 82 (4), pp. 429-435
Zivadinov, R., Lopez-Soriano, A., Weinstock-Guttman, B., Use of MR venography for characterization of the extracranial venous system in patients with multiple sclerosis and healthy control subjects (2011) Radiology, 258 (2), pp. 562-570
Baracchini, C., Perini, P., Calabrese, M., Causin, F., Rinaldi, F., Gallo, P., No evidence of chronic cerebrospinal venous insufficiency at multiple sclerosis onset (2011) Ann Neurol, 69 (1), pp. 90-99
Zivadinov, R., Marr, K., Cutter, G., Prevalence, sensitivity, and specificity of chronic cerebrospinal venous insufficiency in MS (2011) Neurology, 77 (2), pp. 138-144
Centonze, D., Floris, R., Stefanini, M., Proposed chronic cerebrospinal venous insufficiency criteria do not predict multiple sclerosis risk or severity (2011) Ann Neurol, 70 (1), pp. 51-58
Mayer, C.A., Pfeilschifter, W., Lorenz, M.W., The perfect crime? CCSVI not leaving a trace in MS (2011) J Neurol Neurosurg Psychiatry, 82 (4), pp. 436-440
Khan, O., Filippi, M., Freedman, M.S., Chronic cerebrospinal venous insufficiency and multiple sclerosis (2010) Ann Neurol, 67 (3), pp. 286-290
Qiu, J., Venous abnormalities and multiple sclerosis: Another breakthrough claim? (2010) Lancet Neurol, 9 (5), pp. 464-465
Gilroy, J., Bauer, R.B., Krabbenhoft, K.L., Meyer, J.S., Cerebral circulation time in cerebral vascular disease measured by serial angiography (1963) Am J Roentgenol Radium Ther Nucl Med, 90, pp. 490-505
Axel, L., Cerebral blood flow determination by rapid-sequence computed tomography. A theoretical analysis (1980) Radiology, 137 (3), pp. 679-686
Mihara, F., Kuwabara, Y., Tanaka, A., Yoshiura, T., Sasaki, M., Yoshida, T., Masuda, K., Matsushima, T., Reliability of mean transit time obtained using perfusion-weighted MR imaging
comparison with positron emission tomography (2003) Magnetic Resonance Imaging, 21 (1), pp. 33-39. , DOI 10.1016/S0730-725X(02)00629-X, PII S0730725X0200629X
Ito, H., Kanno, I., Takahashi, K., Ibaraki, M., Miura, S., Regional distribution of human cerebral vascular mean transit time measured by positron emission tomography (2003) NeuroImage, 19 (3), pp. 1163-1169. , DOI 10.1016/S1053-8119(03)00156-3
Hoffmann, O., Weih, M., Schreiber, S., Einhaupl, K.M., Valdueza, J.M., Measurement of cerebral circulation time by contrast-enhanced Doppler sonography (2000) Cerebrovascular Diseases, 10 (2), pp. 142-146. , DOI 10.1159/000016043
Jennett, B., Rowan, J.O., Transit time as an index of the cerebral circulation (1972) Prog Brain Res, 35, pp. 365-374
Schaps, P., Weber, K., Cerebral circulation time in acute severe craniocerebral injuries (1976) Z Arztl Fortbild, 70 (13-14), pp. 695-697. , [In German]. Jena
Yoshimoto, Y., Tanaka, Y., Sanada, T., Angiographic assessment of cerebral circulation time for outcome prediction in patients with subarachnoid hemorrhage (2004) Surg Neurol, 62 (2), pp. 115-120. , discussion 120
Ruprecht-Dorfler, P., Brechtelsbauer, D., Schliesser, M., Puls, I., Becker, G., Prognostic and diagnostic value of global cerebral blood flow volume and cerebral transit time in acute stroke (2002) Ultrasound in Medicine and Biology, 28 (11-12), pp. 1405-1411. , DOI 10.1016/S0301-5629(02)00649-X, PII S030156290200649X
Nighoghossian, N., Berthezene, Y., Philippon, B., Adeleine, P., Froment, J.C., Trouillas, P., Hemodynamic parameter assessment with dynamic susceptibility contrast magnetic resonance imaging in unilateral symptomatic internal carotid artery occlusion (1996) Stroke, 27 (3), pp. 474-479
Matsuda, M., Nakasu, S., Nakazawa, T., Handa, J., Cerebral hemodynamics in patients with normal pressure hydrocephalus: Correlation between cerebral circulation time and dementia (1990) Surg Neurol, 34 (6), pp. 396-401
Mast, H., Mohr, J.P., Thompson, J.L., Transcranial Doppler ultrasonography in cerebral arteriovenous malformations: Diagnostic sensitivity and association of flow velocity with spontaneous hemorrhage and focal neurological deficit (1995) Stroke, 26 (6), pp. 1024-1027
Delorme, S., Krix, M., Contrast-enhanced ultrasound for examining tumor biology (2006) Cancer Imaging, 6, pp. 148-152
Polman, C.H., Reingold, S.C., Edan, G., Filippi, M., Hartung, H.-P., Kappos, L., Lublin, F.D., Wolinsky, J.S., Diagnostic criteria for multiple sclerosis: 2005 Revisions to the "McDonald Criteria" (2005) Annals of Neurology, 58 (6), pp. 840-846. , DOI 10.1002/ana.20703
Kurtzke, J.F., Rating neurologic impairment in multiple sclerosis: An expanded disability status scale (EDSS) (1983) Neurology, 33 (11), pp. 1444-1452
Lublin, F.D., Reingold, S.C., Defining the clinical course of multiple sclerosis: Results of an international survey. National Multiple Sclerosis Society (USA) Advisory Committee on Clinical Trials of New Agents in Multiple Sclerosis (1996) Neurology, 46 (4), pp. 907-911
Bland, J.M., Altman, D.G., Statistical methods for assessing agreement between two methods of clinical measurement (1986) Lancet, 1 (8476), pp. 307-310. , PII S0140673686908378
Tanaka, R., Iwasaki, Y., Koprowski, H., Ultrastructural studies of perivascular cuffing cells in multiple sclerosis brain (1975) Am J Pathol, 81 (3), pp. 467-478
Haselhorst, R., Kappos, L., Bilecen, D., Scheffler, K., Mori, D., Radu, E.W., Seelig, J., Dynamic susceptibility contrast MR imaging of plaque development in multiple sclerosis: Application of an extended blood-brain barrier leakage correction (2000) Journal of Magnetic Resonance Imaging, 11 (5), pp. 495-505. , DOI 10.1002/(SICI)1522-2586(200005)11:5<495::AID-JMRI5> 3.0.CO
Moeller, W.-D., Wolschendorf, K., The dependence of cerebral blood flow on age (1978) European Neurology, 17 (5), pp. 276-279
Radiology (ISSN: 1527-1315, 0033-8419, 1527-1315electronic), 2012 Mar; 262(3): 947-955.
Export to BibTeX Export to EndNote
Paper type: Journal Article,
Impact factor: 6.339, 5-year impact factor: 6.738
Url: http://www.scopus.com/inward/record.url?eid=2-s2.0-84858726157&partnerID=40&md5=b27d855a7648b1d9798c6380fea20e47
Keywords: Sonovue, Adult, Article, Brain Blood Flow, Carotid Artery, Cerebral Circulation Time, Chronic Cerebrospinal Venous Insufficiency, Color Ultrasound Flowmetry, Contrast Enhancement, Controlled Study, Disease Association, Drug Tolerability, Extracranial Venous Outflow, Female, Headache, Hot Flush, Human, Internal Jugular Vein, Intracranial Venous Outflow, Major Clinical Study, Multiple Sclerosis, Priority Journal, Prospective Study, Vascular Disease, Venous Reflux, Aged, Analysis Of Variance, Case-Control Studies, Cerebrovascular Circulation, Chi-Square Distribution, Contrast Media, Electrocardiography, Middle Aged, Phospholipids, Prospective Studies, Statistics, Nonparametric, Sulfur Hexafluoride, Ultrasonography, Doppler, Transcranial,
Affiliations:
*** IBB - CNR ***
Institute of Biostructure and Bioimaging, National Research Council of Italy, Federico II University School of Medicine, Via Pansini 5, Edificio 10, 80131 Naples, Italy. marcello.mancini@libero.it
Department of Neurologic Sciences, Federico II University School of Medicine, Edificio 10, 80131 Naples, Italy
Department of Biomorphological and Functional Science, Federico II University School of Medicine, Edificio 10, Via Pansini 5, 80131 Naples, Italy
SDN Foundation, Institute of Diagnostic and Nuclear Development, Naples, Italy
Hermitage Capodimonte IDC, Naples, Italy
References:
Lucchinetti, C., Bruck, W., Parisi, J., Scheithauer, B., Rodriguez, M., Lassmann, H., Heterogeneity of multiple sclerosis lesions: Implications for the pathogenesis of demyelination (2000) Annals of Neurology, 47 (6), pp. 707-717. , DOI 10.1002/1531-8249(200006)47:6<707::AID-ANA3> 3.0.CO
Lassmann, H., Hypoxia-like tissue injury as a component of multiple sclerosis lesions (2003) Journal of the Neurological Sciences, 206 (2), pp. 187-191. , DOI 10.1016/S0022-510X(02)00421-5, PII S0022510X02004215
Ge, Y., Law, M., Johnson, G., Herbert, J., Babb, J.S., Mannon, L.J., Grossman, R.I., Dynamic susceptibility contrast perfusion MR imaging of multiple sclerosis lesions: Characterizing hemodynamic impairment and inflammatory activity (2005) American Journal of Neuroradiology, 26 (6), pp. 1539-1547
Qiu, W., Raven, S., Wu, J.S., Carroll, W.M., Mastaglia, F.L., Kermode, A.G., Wedge-shaped medullary lesions in multiple sclerosis (2010) J Neurol Sci, 290 (1-2), pp. 190-193
Putnam, T.J., Evidences of vascular occlusion in multiple sclerosis and "encephalomyelitis" (1937) Arch Neurol Psychiatry, 37 (6), pp. 1298-1321
Zamboni, P., Galeotti, R., Menegatti, E., Chronic cerebrospinal venous insufficiency in patients with multiple sclerosis (2009) J Neurol Neurosurg Psychiatry, 80 (4), pp. 392-399
Zamboni, P., Menegatti, E., Galeotti, R., The value of cerebral Doppler venous haemodynamics in the assessment of multiple sclerosis (2009) J Neurol Sci, 282 (1-2), pp. 21-27
Doepp, F., Paul, F., Valdueza, J.M., Schmierer, K., Schreiber, S.J., No cerebrocervical venous congestion in patients with multiple sclerosis (2010) Ann Neurol, 68 (2), pp. 173-183
Sundström, P., Wåhlin, A., Ambarki, K., Birgander, R., Eklund, A., Malm, J., Venous and cerebrospinal fluid flow in multiple sclerosis: A case-control study (2010) Ann Neurol, 68 (2), pp. 255-259
Wattjes, M.P., Van Oosten, B.W., De Graaf, W.L., No association of abnormal cranial venous drainage with multiple sclerosis: A magnetic resonance venography and flow-quantification study (2011) J Neurol Neurosurg Psychiatry, 82 (4), pp. 429-435
Zivadinov, R., Lopez-Soriano, A., Weinstock-Guttman, B., Use of MR venography for characterization of the extracranial venous system in patients with multiple sclerosis and healthy control subjects (2011) Radiology, 258 (2), pp. 562-570
Baracchini, C., Perini, P., Calabrese, M., Causin, F., Rinaldi, F., Gallo, P., No evidence of chronic cerebrospinal venous insufficiency at multiple sclerosis onset (2011) Ann Neurol, 69 (1), pp. 90-99
Zivadinov, R., Marr, K., Cutter, G., Prevalence, sensitivity, and specificity of chronic cerebrospinal venous insufficiency in MS (2011) Neurology, 77 (2), pp. 138-144
Centonze, D., Floris, R., Stefanini, M., Proposed chronic cerebrospinal venous insufficiency criteria do not predict multiple sclerosis risk or severity (2011) Ann Neurol, 70 (1), pp. 51-58
Mayer, C.A., Pfeilschifter, W., Lorenz, M.W., The perfect crime? CCSVI not leaving a trace in MS (2011) J Neurol Neurosurg Psychiatry, 82 (4), pp. 436-440
Khan, O., Filippi, M., Freedman, M.S., Chronic cerebrospinal venous insufficiency and multiple sclerosis (2010) Ann Neurol, 67 (3), pp. 286-290
Qiu, J., Venous abnormalities and multiple sclerosis: Another breakthrough claim? (2010) Lancet Neurol, 9 (5), pp. 464-465
Gilroy, J., Bauer, R.B., Krabbenhoft, K.L., Meyer, J.S., Cerebral circulation time in cerebral vascular disease measured by serial angiography (1963) Am J Roentgenol Radium Ther Nucl Med, 90, pp. 490-505
Axel, L., Cerebral blood flow determination by rapid-sequence computed tomography. A theoretical analysis (1980) Radiology, 137 (3), pp. 679-686
Mihara, F., Kuwabara, Y., Tanaka, A., Yoshiura, T., Sasaki, M., Yoshida, T., Masuda, K., Matsushima, T., Reliability of mean transit time obtained using perfusion-weighted MR imaging
comparison with positron emission tomography (2003) Magnetic Resonance Imaging, 21 (1), pp. 33-39. , DOI 10.1016/S0730-725X(02)00629-X, PII S0730725X0200629X
Ito, H., Kanno, I., Takahashi, K., Ibaraki, M., Miura, S., Regional distribution of human cerebral vascular mean transit time measured by positron emission tomography (2003) NeuroImage, 19 (3), pp. 1163-1169. , DOI 10.1016/S1053-8119(03)00156-3
Hoffmann, O., Weih, M., Schreiber, S., Einhaupl, K.M., Valdueza, J.M., Measurement of cerebral circulation time by contrast-enhanced Doppler sonography (2000) Cerebrovascular Diseases, 10 (2), pp. 142-146. , DOI 10.1159/000016043
Jennett, B., Rowan, J.O., Transit time as an index of the cerebral circulation (1972) Prog Brain Res, 35, pp. 365-374
Schaps, P., Weber, K., Cerebral circulation time in acute severe craniocerebral injuries (1976) Z Arztl Fortbild, 70 (13-14), pp. 695-697. , [In German]. Jena
Yoshimoto, Y., Tanaka, Y., Sanada, T., Angiographic assessment of cerebral circulation time for outcome prediction in patients with subarachnoid hemorrhage (2004) Surg Neurol, 62 (2), pp. 115-120. , discussion 120
Ruprecht-Dorfler, P., Brechtelsbauer, D., Schliesser, M., Puls, I., Becker, G., Prognostic and diagnostic value of global cerebral blood flow volume and cerebral transit time in acute stroke (2002) Ultrasound in Medicine and Biology, 28 (11-12), pp. 1405-1411. , DOI 10.1016/S0301-5629(02)00649-X, PII S030156290200649X
Nighoghossian, N., Berthezene, Y., Philippon, B., Adeleine, P., Froment, J.C., Trouillas, P., Hemodynamic parameter assessment with dynamic susceptibility contrast magnetic resonance imaging in unilateral symptomatic internal carotid artery occlusion (1996) Stroke, 27 (3), pp. 474-479
Matsuda, M., Nakasu, S., Nakazawa, T., Handa, J., Cerebral hemodynamics in patients with normal pressure hydrocephalus: Correlation between cerebral circulation time and dementia (1990) Surg Neurol, 34 (6), pp. 396-401
Mast, H., Mohr, J.P., Thompson, J.L., Transcranial Doppler ultrasonography in cerebral arteriovenous malformations: Diagnostic sensitivity and association of flow velocity with spontaneous hemorrhage and focal neurological deficit (1995) Stroke, 26 (6), pp. 1024-1027
Delorme, S., Krix, M., Contrast-enhanced ultrasound for examining tumor biology (2006) Cancer Imaging, 6, pp. 148-152
Polman, C.H., Reingold, S.C., Edan, G., Filippi, M., Hartung, H.-P., Kappos, L., Lublin, F.D., Wolinsky, J.S., Diagnostic criteria for multiple sclerosis: 2005 Revisions to the "McDonald Criteria" (2005) Annals of Neurology, 58 (6), pp. 840-846. , DOI 10.1002/ana.20703
Kurtzke, J.F., Rating neurologic impairment in multiple sclerosis: An expanded disability status scale (EDSS) (1983) Neurology, 33 (11), pp. 1444-1452
Lublin, F.D., Reingold, S.C., Defining the clinical course of multiple sclerosis: Results of an international survey. National Multiple Sclerosis Society (USA) Advisory Committee on Clinical Trials of New Agents in Multiple Sclerosis (1996) Neurology, 46 (4), pp. 907-911
Bland, J.M., Altman, D.G., Statistical methods for assessing agreement between two methods of clinical measurement (1986) Lancet, 1 (8476), pp. 307-310. , PII S0140673686908378
Tanaka, R., Iwasaki, Y., Koprowski, H., Ultrastructural studies of perivascular cuffing cells in multiple sclerosis brain (1975) Am J Pathol, 81 (3), pp. 467-478
Haselhorst, R., Kappos, L., Bilecen, D., Scheffler, K., Mori, D., Radu, E.W., Seelig, J., Dynamic susceptibility contrast MR imaging of plaque development in multiple sclerosis: Application of an extended blood-brain barrier leakage correction (2000) Journal of Magnetic Resonance Imaging, 11 (5), pp. 495-505. , DOI 10.1002/(SICI)1522-2586(200005)11:5<495::AID-JMRI5> 3.0.CO
Moeller, W.-D., Wolschendorf, K., The dependence of cerebral blood flow on age (1978) European Neurology, 17 (5), pp. 276-279
Multiple sclerosis: cerebral circulation time
Purpose: To assess cerebral circulation times (CCTs) in patients with multiple sclerosis (MS) and control subjects by using contrast material-enhanced ultrasonography (US) to determine whether vascular abnormalities can be detected in this disease. Materials and Methods: This study was approved by the local ethics committee, and informed consent was obtained from all subjects. One hundred three patients with MS and 42 control subjects underwent extracranial and transcranial venous echo-color Doppler ultrasonography (US) and contrast-enhanced US. CCT was defined as the difference in arrival time of the US contrast agent bolus between the carotid artery and the internal jugular vein. The presence of chronic cerebrospinal venous insufficiency (CCSVI) was defined according to previously reported criteria for the extracranial and transcranial US techniques. Nonparametric statistics, including the Mann-Whitney U test and the Kruskal-Wallis analysis of variance, were used to compare contrast-enhanced US parameters between groups. Results: The longest and average CCTs were substantially prolonged in patients with MS compared with those in control subjects (median longest CCT in patients with MS, 6.47 seconds [range, 3.29-29.24 seconds]; that in control subjects, 5.54 seconds [range, 2.57-7.63 seconds]; P < .001; median average CCT in patients with MS, 5.76 seconds [range, 2.64-17.51 seconds]; that in control subjects, 5.01 seconds [range, 2.57-7.06 seconds]; P < .002). No correlation was found between CCTs and clinical parameters. The prevalence of CCSVI was higher in patients with MS than in control subjects (77% vs 28%, P < .0001). CCT was not significantly different between patients with MS who had CCSVI and patients with MS who did not (P = .182). Conclusion: These results suggest that contrast-enhanced US with CCT assessment may have a role in the evaluation of cerebral blood flow in patients with MS and that a vascular impairment could be associated with MS. The finding of a prolonged CCT at contrast-enhanced US does not result from outflow impairment. Further studies are required to verify these observations and to clarify if CCT and CCSVI have any physiologic and clinical relevance in MS. © RSNA, 2012.
Purpose: To assess cerebral circulation times (CCTs) in patients with multiple sclerosis (MS) and control subjects by using contrast material-enhanced ultrasonography (US) to determine whether vascular abnormalities can be detected in this disease. Materials and Methods: This study was approved by the local ethics committee, and informed consent was obtained from all subjects. One hundred three patients with MS and 42 control subjects underwent extracranial and transcranial venous echo-color Doppler ultrasonography (US) and contrast-enhanced US. CCT was defined as the difference in arrival time of the US contrast agent bolus between the carotid artery and the internal jugular vein. The presence of chronic cerebrospinal venous insufficiency (CCSVI) was defined according to previously reported criteria for the extracranial and transcranial US techniques. Nonparametric statistics, including the Mann-Whitney U test and the Kruskal-Wallis analysis of variance, were used to compare contrast-enhanced US parameters between groups. Results: The longest and average CCTs were substantially prolonged in patients with MS compared with those in control subjects (median longest CCT in patients with MS, 6.47 seconds [range, 3.29-29.24 seconds]; that in control subjects, 5.54 seconds [range, 2.57-7.63 seconds]; P < .001; median average CCT in patients with MS, 5.76 seconds [range, 2.64-17.51 seconds]; that in control subjects, 5.01 seconds [range, 2.57-7.06 seconds]; P < .002). No correlation was found between CCTs and clinical parameters. The prevalence of CCSVI was higher in patients with MS than in control subjects (77% vs 28%, P < .0001). CCT was not significantly different between patients with MS who had CCSVI and patients with MS who did not (P = .182). Conclusion: These results suggest that contrast-enhanced US with CCT assessment may have a role in the evaluation of cerebral blood flow in patients with MS and that a vascular impairment could be associated with MS. The finding of a prolonged CCT at contrast-enhanced US does not result from outflow impairment. Further studies are required to verify these observations and to clarify if CCT and CCSVI have any physiologic and clinical relevance in MS. © RSNA, 2012.
Multiple sclerosis: cerebral circulation time
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Multiple sclerosis: cerebral circulation time
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Impact Factor: 3.578
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Mancini M, Brescia Morra V, Di Donato O, Maglio V, Lanzillo R, Liuzzi R, Brunetti A, Salvatore M
* Contrast-Enhanced Ultrasound Evaluation Of The Cerebral Circulation Time In Patients With Multiple Sclerosis (268 views)
J Ultrasound Med, 2012; N/D: 49-49.
Impact Factor: 1.532
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Malferrari G, Del Sette M, Zedde M, Sanguigni S, Carraro C, Baracchini C, Mancini M, Stolz E
* Italian multicenter study on venous hemodynamics in multiple sclerosis: Advanced Sonological Protocol (312 views)
Perspect Med (ISSN: 2211-968x), 2012; 1-12: 399-403.
Impact Factor: 1.132
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Pizzuti LM, Todaro P, Caleo A, Pace L, Vajro P
* Lymph node fine needle cytology in the diagnosis of infectious diseases and instrumental guides: Ultrasound and computed tomography (590 views)
Infez Med (ISSN: 1124-9390), 2012; 20(SUPPL.3): 26-29.
Impact Factor: 0
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Bastianello S, Romani A, Viselner G, Tibaldi EC, Giugni E, Altieri M, Cecconi P, Mendozzi L, Farina M, Mariani D, Galassi A, Quattrini C, Mancini M, Brescia VM, Lagace A, Mcdonald S, Bono G, Bergamaschi R
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Bmc Neurol (ISSN: 1471-2377, 1471-2377linking), 2011 Oct 26; 11: 132-132.
Impact Factor: 2.167
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Perrone-filardi P, Dellegrottaglie S, Rudd JH, Costanzo P, Marciano C, Vassallo E, Marsico F, Ruggiero D, Petretta MP, Chiariello M, Cuocolo A
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Eur J Nucl Med (ISSN: 1619-7089, 1619-7070, 0340-6997), 2011 May; 38(5): 969-975.
Impact Factor: 4.991
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Pappata S, Varrone A, Vicidomini C, Milan G, De Falco C, Sansone V, Iavarone A, Comerci M, Loré E, Panico M, Quarantelli M, Postiglione A, Salvatore M
* SPECT imaging of GABAA/benzodiazepine receptors and cerebral perfusion in mild cognitive impairment (504 views)
Eur J Nucl Med (ISSN: 1619-7070, 1619-7089, 0340-6997), 2010 Jun; 37(6): 1156-1163.
Impact Factor: 5.036
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Santulli G, Ciccarelli M, Palumbo G, Campanile A, Galasso G, Ziaco B, Altobelli GG, Cimini V, Piscione F, D'Andrea LD, Pedone C, Trimarco B, Iaccarino G
* In vivo properties of the proangiogenic peptide QK (417 views)
J Transl Med (ISSN: 1479-5876, 1479-5876electronic, 1479-5876linking), 2009 Jun 8; 7: 41-41.
Impact Factor: 3.407
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Cittadini A, Monti MG, Castiello MC, D'Arco E, Galasso G, Sorriento D, Saldamarco L, De Paulis A, Napoli R, Iaccarino G, Saccà L
* Insulin-like growth factor-1 protects from vascular stenosis and accelerates re-endothelialization in a rat model of carotid artery injury (466 views)
J Thromb Haemost Journal Of Thrombosis And Haemostasis (ISSN: 1538-7933), 2009; 7(11): 1920-1928.
Impact Factor: 6.069
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Varrone A, Pagani M, Salvatore E, Salmaso D, Sansone V, Amboni M, Nobili F, De Michele G, Filla A, Barone P, Pappata S, Salvatore M
* Identification by [Tc-99]ECD SPECT of anterior cingulate hypoperfusion in progressive supranuclear palsy, in comparison with Parkinson's disease (508 views)
Eur J Nucl Med (ISSN: 1619-7070, 1619-7089, 0340-6997), 2007 Jul; 34(7): 1071-1081.
Impact Factor: 4.101
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Paladini D, Sglavo G, Quarantelli M, D'Armiento MR, Martinelli P, Salvatore M
* Large infratentorial subdural hemorrhage diagnosed by ultrasound and MRI in a second-trimester fetus [1] (378 views)
Ultrasound Obst Gyn (ISSN: 0960-7692, 1469-0705), 2005 Dec; 26(7): 789-791.
Impact Factor: 2.43
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Colao A, Di Somma C, Cuocolo A, Spinelli L, Acampa W, Spiezia S, Rota F, Savanelli MC, Lombardi G
* Does a gender-related effect of growth hormone (GH) replacement exist on cardiovascular risk factors, cardiac morphology, and performance and atherosclerosis? Results of a two-year open, prospective study in young adult men and women with severe GH deficiency (448 views)
J Clin Endocrinol Metab (ISSN: 0021-972x), 2005 Sep; 90(9): 5146-5155.
Impact Factor: 6.02
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Mancini M, Daniele S, Raffio T, Liuzzi R, Sabbatini M, Cianciaruso B, Ferrara LA, Salvatore M
* Intra and interobserver variability of renal allograft ultrasound volume and resistive index measurements (408 views)
Radiol Med (ISSN: 0033-8362, 1826-6983, 1826-6983electronic), 2005 Apr; 109(4): 385-394.
Impact Factor: 1.368
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Hesse B, Tagil K, Cuocolo A, Anagnostopoulos C, Bardies M, Bax J, Bengel F, Busemann Sokole E, Davies G, Dondi M, Edenbrandt L, Franken P, Kjaer A, Knuuti J, Lassmann M, Ljungberg M, Marcassa C, Marie PY, Mckiddie F, O'connor M, Prvuolovich E, Underwood R
* 3. 0 T perfusion MR imaging (730 views)
Rivista Di Neuroradiologia (ISSN: 1120-9976), 2004; 17(6): 807-812.
Impact Factor: 0.023
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Iaccarino G, Ciccarelli M, Sorriento D, Cipolletta E, Cerullo V, Iovino GL, Paudice A, Elia A, Santulli G, Campanile A, Arcucci O, Pastore L, Salvatore F, Condorelli G, Trimarco B
* AKT participates in endothelial dysfunction in hypertension (356 views)
Circulationcirculation (ISSN: 0009-7322), 2004; 109(21): 2587-2593.
Impact Factor: 12.563
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Leosco D, Iaccarino G, Cipolletta E, De Santis D, Pisani E, Trimarco V, Ferrara N, Abete P, Sorriento D, Rengo F, Trimarco B
* Exercise restores β-adrenergic vasorelaxation in aged rat carotid arteries (334 views)
Am J Physiol Heart Circ Physiol American Journal Of Physiology Heart And Circulatory Physiology (ISSN: 0363-6135), 2003; 285(154-1): H369-H369.
Impact Factor: 3.658
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Pauciullo P, Giannino A, De Michele M, Gentile M, Liguori R, Argiriou A, Carlotto A, Faccenda F, Mancini M, Bond MG, De Simone V, Rubba P
* Increased carotid artery intima-media thickness is associated with a novel mutation of low-density lipoprotein receptor independently of major cardiovascular risk factors (705 views)
Metab Clin Exp (ISSN: 0026-0495, 1532-8600), 2003; 52(11): 1433-1438.
Impact Factor: 2.013
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Varrone A, Pappata S, Caracò C, Soricelli A, Milan G, Quarantelli M, Alfano B, Postiglione A, Salvatore M
* Voxel-based comparison of rCBF SPET images in frontotemporal dementia and Alzheimer's disease highlights the involvement of different cortical networks (474 views) (PDF 309 views)
Eur J Nucl Med (ISSN: 0340-6997, 1619-7070, 1619-7089), 2002 Nov; 29(11): 1447-1454.
Impact Factor: 3.568
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Colao A, Spinelli L, Cuocolo A, Spiezia S, Pivonello R, Di Somma C, Bonaduce D, Salvatore M, Lombardi G
* Cardiovascular consequences of early-onset growth hormone excess (422 views)
J Clin Endocrinol Metab (ISSN: 0021-972x), 2002 Jul; 87(7): 3097-3104.
Impact Factor: 5.199
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Meyer Lindenberg A, Miletich RS, Kohn PD, Esposito G, Carson RE, Quarantelli M, Weinberger DR, Berman KF
* Reduced prefrontal activity predicts exaggerated striatal dopaminergic function in schizophrenia (921 views)
Nat Neurosci (ISSN: 1097-6256), 2002 Mar; 5(3): 267-271.
Impact Factor: 14.857
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Varrone A, Soricelli A, Postiglione A, Salvatore M
Comparison between cortical distribution of I-123 lomazenil and Tc-99m HMPAO in patients with Alzheimer's disease using SPECT (315 views)
Clin Nucl Med (ISSN: 0363-9762, 1536-0229, 1536-0229electronic), 1999 Sep; 24(9): 660-665.
Impact Factor: 0.253
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De Michele G, Mainenti PP, Soricelli A, Di Salle F, Salvatore E, Longobardi MR, Postiglione A, Salvatore M, Filla A
Cerebral blood flow in spinocerebellar degenerations: a single photon emission tomography study in 28 patients (260 views)
J Neurol (ISSN: 0340-5354, 1432-1459, 1432-1459electronic), 1998 Sep; 245(9): 603-608.
Impact Factor: 2.3
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Postiglione A, Soricelli A, Grossi D, Romano M, Mainenti PP, Ruocco A, Fragrassi N, Chiacchio L, Milan G, De Chiara S, Brunetti A
Changes in cerebral blood flow during cognitive activation evaluated by single photon emission computed tomography in patients with Alzheimer's disease (449 views)
Alzheimer S Res (ISSN: 1356-918x), 1997 Jun; 3(3): 93-99.
Impact Factor: 0
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Iaccarino V, Tedeschi E, Brunetti A, Soricelli A, Salvatore M
Congenital agenesis/aplasia of the internal carotid arteries: MRA and SPECT findings (212 views)
J Comput Assisted Tomogr (ISSN: 0363-8715), 1995 Nov; 19(6): 987-990.
Impact Factor: 1.263
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Soricelli A, Postiglione A, Cuocolo A, De Chiara S, Ruocco A, Brunetti A, Salvatore M, Ell PJ
EFFECT OF ADENOSINE ON CEREBRAL BLOOD-FLOW AS EVALUATED BY SINGLE-PHOTON EMISSION COMPUTED-TOMOGRAPHY IN NORMAL SUBJECTS AND IN PATIENTS WITH OCCLUSIVE CAROTID DISEASE - A COMPARISON WITH ACETAZOLAMIDE (256 views)
Stroke (ISSN: 0039-2499), 1995 Sep; 26(9): 1572-1576.
Impact Factor: 4.323
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Ferrara LA, Mancini M, Iannuzzi R, Marotta T, Gaeta I, Pasanisi F, Postiglione A, Guida L
CAROTID DIAMETER AND BLOOD-FLOW VELOCITIES IN CEREBRAL-CIRCULATION IN HYPERTENSIVE PATIENTS (280 views)
Stroke (ISSN: 0039-2499), 1995 Mar; 26(3): 418-421.
Impact Factor: 4.323
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Ferrara LA, Mancini M, Celentano A, Galderisi M, Iannuzzi R, Marotta T, Gaeta I
Early changes of the arterial carotid wall in uncomplicated primary hypertensive patients: Study by ultrasound high-resolution B-mode imaging (284 views)
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Impact Factor: 5.317
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Miletich RS, Quarantelli M, Di Chiro G
REGIONAL CEREBRAL BLOOD-FLOW IMAGING WITH TC-99M-BICISATE SPECT IN ASYMMETRIC PARKINSONS-DISEASE - STUDIES WITH AND WITHOUT CHRONIC DRUG-THERAPY (513 views)
Journal Of Cerebral Blood Flow And Metabolism (ISSN: 0271-678x), 1994 Jan; 14: S106-S106.
Impact Factor: 5.836
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Postiglione A, Soricelli A, Cicerano U, Mansi L, De Chiara S, Gallotta G, Schettini G, Salvatore M
Effect of acute administration of l-acetyl carnitine on cerebral blood flow in patients with chronic cerebral infarct (364 views)
Pharmacol Res (ISSN: 1043-6618, 1096-1186electronic, 1043-6618linking), 1991 Apr; 23(3): 241-246.
Impact Factor: 0.47
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Grossi D, Trojano L, Chiacchio L, Soricelli A, Mansi L, Postiglione A, Salvatore M
Mixed transcortical aphasia: Clinical features and neuroanatomical correlates. A possible role of the right hemisphere (403 views)
Eur Neurol (ISSN: 0014-3022), 1991; 31(4): 204-211.
Impact Factor: 1.22
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Mancini M, De Chiara S, Ferrara LA, Gallotta G, Postiglione A
TRANSCRANIAL DOPPLER EVALUATION OF CEREBROVASCULAR REACTIVITY TO ACETAZOLAMIDE IN NORMAL SUBJECTS (665 views)
15th World Congress Angiology Rome, 1989; 20(4): 284-284.
Impact Factor: 0
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Mancini M, Ferrara LA
Transcranial Doppler Evaluation Of Middle Cerebral Artery In Patients With Carotid Artery Stenosis (255 views)
Progress In Angiology Eds Minerva Medica Torino, 1988; N/D: 73-74.
Impact Factor: 0
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* Advances in SPECT Methodology (313 views)
Int Rev Neurobiol (ISSN: 0074-77429780128154182, 2162-5514electronic), 2018 Sep; 141: 77-96.
Impact Factor: 3.36
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Marr K, Jakimovski D, Mancini M, Carl E, Zivadinov R
* Jugular Venous Flow Quantification Using Doppler Sonography (975 views)
Ultrasound Med Biol (ISSN: 0301-5629linking, 1879-291xelectronic), 2018 Aug; 44(8): 1762-1769.
Impact Factor: 2.494
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Caprio MG, Marr K, Gandhi S, Jakimovski D, Hagemeier J, Weinstock-guttman B, Zivadinov R, Mancini M
* Centralized and local color Doppler ultrasound reading agreement for diagnosis of the chronic cerebrospinal venous insufficiency in patients with Multiple Sclerosis (237 views)
Curr Neurovasc Res (ISSN: 1567-2026, 1567-2026linking), 2017 Jul 17; 14(3): 266-273.
Impact Factor: 1.716
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Mancini M, Marr K, Caprio MG, Hagemeier Jesper Gandhi S, Jakimovski D, Chandra A, Weinstock-guttman B, Zivadinov R
* Centralized and local Doppler sonography reading agreement for diagnosis of the chronic cerebrospinal venous insufficiency (CCSVI) (243 views)
6th Annual Meeting Of The International Society For Neurovascular Disease, 2016 Apr; N/D: N/D-N/D.
Impact Factor: 0
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Mancini M, Greco A, Tedeschi E, Palma G, Ragucci M, Bruzzone MG, Coda ARD, Torino E, Scotti A, Zucca I, Salvatore M
* Head and Neck Veins of the Mouse. A Magnetic Resonance, Micro Computed Tomography and High Frequency Color Doppler Ultrasound Study (1290 views) (PDF 235 views)
Plosone (ISSN: 1932-6203, 1932-6203electronic, 1932-6203linking), 2015 Jun 11; 10(6): e0129912-e0129912.
Impact Factor: 3.057
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Mannelli L, MacDonald L, Mancini M, Ferguson M, Shuman WP, Ragucci M, Monti S, Xu D, Yuan C, Mitsumori LM
* Dual energy computed tomography quantification of carotid plaques calcification: comparison between monochromatic and polychromatic energies with pathology correlation (276 views)
Eur Radiol (ISSN: 0938-7994, 1432-1084electronic, 0938-7994linking), 2014 Dec 24; 25(5): 1238-1246.
Impact Factor: 4.014
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Mancini M, Lanzillo R, Liuzzi R, Di Donato O, Ragucci M, Monti S, Salvatore E, Morra VB, Salvatore M
* Internal jugular vein blood flow in multiple sclerosis patients and matched controls (466 views) (PDF 202 views)
Plosone (ISSN: 1932-6203, 1932-6203electronic, 1932-6203linking), 2014 Mar 27; 9(3): e92730-e92730.
Impact Factor: 3.234
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Comi G, Battaglia MA, Bertolotto A, Del Sette M, Ghezzi A, Malferrari G, Salvetti M, Sormani MP, Tesio L, Stolz E, Zaratin P, Mancardi G, Mancini M
* Observational case-control study of the prevalence of chronic cerebrospinal venous insufficiency in multiple sclerosis: results from the CoSMo study (294 views)
Mult Scler (ISSN: 1477-0970, 1352-4585, 1352-4585linking), 2013 Oct; 19(11): 1508-1517.
Impact Factor: 4.863
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Lanzillo R, Mancini M, Liuzzi R, Di Donato O, Salvatore E, Maglio V, Vacca G, Amato L, D'Anna G, Brunetti A, Brescia Morra V
* Chronic cerebrospinal venous insufficiency in multiple sclerosis: a highly prevalent age-dependent phenomenon (539 views)
Bmc Neurol (ISSN: 1471-2377, 1471-2377linking), 2013 Feb 13; 13: 20-20.
Impact Factor: 2.486
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Petretta M, Cuocolo A
In search of a marker of vulnerable carotid plaque: is the key in the heart? (312 views)
Atherosclerosis (ISSN: 1879-1484, 0021-9150), 2012 Jul; 223(1): 95-97.
Impact Factor: 3.706
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Lanzillo R, Mancini M, Liuzzi R, Salvatore E, Magli V, Di Donato O, Vacca G, Amato L, Orefice G, Brunetti A, Morra VB
* Prevalence of chronic cerebrospinal venous insufficiency in MS and its correlations with clinical features (277 views)
J Neurol (ISSN: 0340-5354, 1432-1459, 1432-1459electronic), 2012 Jun; 259: N/D-N/D.
Impact Factor: 3.578
View Export to BibTeX Export to EndNote
Mancini M, Brescia Morra V, Di Donato O, Maglio V, Lanzillo R, Liuzzi R, Brunetti A, Salvatore M
* Contrast-Enhanced Ultrasound Evaluation Of The Cerebral Circulation Time In Patients With Multiple Sclerosis (268 views)
J Ultrasound Med, 2012; N/D: 49-49.
Impact Factor: 1.532
View Export to BibTeX Export to EndNote
Malferrari G, Del Sette M, Zedde M, Sanguigni S, Carraro C, Baracchini C, Mancini M, Stolz E
* Italian multicenter study on venous hemodynamics in multiple sclerosis: Advanced Sonological Protocol (312 views)
Perspect Med (ISSN: 2211-968x), 2012; 1-12: 399-403.
Impact Factor: 1.132
View Export to BibTeX Export to EndNote
Pizzuti LM, Todaro P, Caleo A, Pace L, Vajro P
* Lymph node fine needle cytology in the diagnosis of infectious diseases and instrumental guides: Ultrasound and computed tomography (590 views)
Infez Med (ISSN: 1124-9390), 2012; 20(SUPPL.3): 26-29.
Impact Factor: 0
View Export to BibTeX Export to EndNote
Bastianello S, Romani A, Viselner G, Tibaldi EC, Giugni E, Altieri M, Cecconi P, Mendozzi L, Farina M, Mariani D, Galassi A, Quattrini C, Mancini M, Brescia VM, Lagace A, Mcdonald S, Bono G, Bergamaschi R
* Chronic cerebrospinal venous insufficiency in multiple sclerosis: clinical correlates from a multicentre study (366 views)
Bmc Neurol (ISSN: 1471-2377, 1471-2377linking), 2011 Oct 26; 11: 132-132.
Impact Factor: 2.167
View Export to BibTeX Export to EndNote
Perrone-filardi P, Dellegrottaglie S, Rudd JH, Costanzo P, Marciano C, Vassallo E, Marsico F, Ruggiero D, Petretta MP, Chiariello M, Cuocolo A
* Molecular imaging of atherosclerosis in translational medicine (756 views)
Eur J Nucl Med (ISSN: 1619-7089, 1619-7070, 0340-6997), 2011 May; 38(5): 969-975.
Impact Factor: 4.991
View Export to BibTeX Export to EndNote
Pappata S, Varrone A, Vicidomini C, Milan G, De Falco C, Sansone V, Iavarone A, Comerci M, Loré E, Panico M, Quarantelli M, Postiglione A, Salvatore M
* SPECT imaging of GABAA/benzodiazepine receptors and cerebral perfusion in mild cognitive impairment (504 views)
Eur J Nucl Med (ISSN: 1619-7070, 1619-7089, 0340-6997), 2010 Jun; 37(6): 1156-1163.
Impact Factor: 5.036
View Export to BibTeX Export to EndNote
Santulli G, Ciccarelli M, Palumbo G, Campanile A, Galasso G, Ziaco B, Altobelli GG, Cimini V, Piscione F, D'Andrea LD, Pedone C, Trimarco B, Iaccarino G
* In vivo properties of the proangiogenic peptide QK (417 views)
J Transl Med (ISSN: 1479-5876, 1479-5876electronic, 1479-5876linking), 2009 Jun 8; 7: 41-41.
Impact Factor: 3.407
View Export to BibTeX Export to EndNote
Cittadini A, Monti MG, Castiello MC, D'Arco E, Galasso G, Sorriento D, Saldamarco L, De Paulis A, Napoli R, Iaccarino G, Saccà L
* Insulin-like growth factor-1 protects from vascular stenosis and accelerates re-endothelialization in a rat model of carotid artery injury (466 views)
J Thromb Haemost Journal Of Thrombosis And Haemostasis (ISSN: 1538-7933), 2009; 7(11): 1920-1928.
Impact Factor: 6.069
View Export to BibTeX Export to EndNote
Varrone A, Pagani M, Salvatore E, Salmaso D, Sansone V, Amboni M, Nobili F, De Michele G, Filla A, Barone P, Pappata S, Salvatore M
* Identification by [Tc-99]ECD SPECT of anterior cingulate hypoperfusion in progressive supranuclear palsy, in comparison with Parkinson's disease (508 views)
Eur J Nucl Med (ISSN: 1619-7070, 1619-7089, 0340-6997), 2007 Jul; 34(7): 1071-1081.
Impact Factor: 4.101
View Export to BibTeX Export to EndNote
Paladini D, Sglavo G, Quarantelli M, D'Armiento MR, Martinelli P, Salvatore M
* Large infratentorial subdural hemorrhage diagnosed by ultrasound and MRI in a second-trimester fetus [1] (378 views)
Ultrasound Obst Gyn (ISSN: 0960-7692, 1469-0705), 2005 Dec; 26(7): 789-791.
Impact Factor: 2.43
View Export to BibTeX Export to EndNote
Colao A, Di Somma C, Cuocolo A, Spinelli L, Acampa W, Spiezia S, Rota F, Savanelli MC, Lombardi G
* Does a gender-related effect of growth hormone (GH) replacement exist on cardiovascular risk factors, cardiac morphology, and performance and atherosclerosis? Results of a two-year open, prospective study in young adult men and women with severe GH deficiency (448 views)
J Clin Endocrinol Metab (ISSN: 0021-972x), 2005 Sep; 90(9): 5146-5155.
Impact Factor: 6.02
View Export to BibTeX Export to EndNote
Mancini M, Daniele S, Raffio T, Liuzzi R, Sabbatini M, Cianciaruso B, Ferrara LA, Salvatore M
* Intra and interobserver variability of renal allograft ultrasound volume and resistive index measurements (408 views)
Radiol Med (ISSN: 0033-8362, 1826-6983, 1826-6983electronic), 2005 Apr; 109(4): 385-394.
Impact Factor: 1.368
View Export to BibTeX Export to EndNote
Hesse B, Tagil K, Cuocolo A, Anagnostopoulos C, Bardies M, Bax J, Bengel F, Busemann Sokole E, Davies G, Dondi M, Edenbrandt L, Franken P, Kjaer A, Knuuti J, Lassmann M, Ljungberg M, Marcassa C, Marie PY, Mckiddie F, O'connor M, Prvuolovich E, Underwood R
* 3. 0 T perfusion MR imaging (730 views)
Rivista Di Neuroradiologia (ISSN: 1120-9976), 2004; 17(6): 807-812.
Impact Factor: 0.023
View Export to BibTeX Export to EndNote
Iaccarino G, Ciccarelli M, Sorriento D, Cipolletta E, Cerullo V, Iovino GL, Paudice A, Elia A, Santulli G, Campanile A, Arcucci O, Pastore L, Salvatore F, Condorelli G, Trimarco B
* AKT participates in endothelial dysfunction in hypertension (356 views)
Circulationcirculation (ISSN: 0009-7322), 2004; 109(21): 2587-2593.
Impact Factor: 12.563
View Export to BibTeX Export to EndNote
Leosco D, Iaccarino G, Cipolletta E, De Santis D, Pisani E, Trimarco V, Ferrara N, Abete P, Sorriento D, Rengo F, Trimarco B
* Exercise restores β-adrenergic vasorelaxation in aged rat carotid arteries (334 views)
Am J Physiol Heart Circ Physiol American Journal Of Physiology Heart And Circulatory Physiology (ISSN: 0363-6135), 2003; 285(154-1): H369-H369.
Impact Factor: 3.658
View Export to BibTeX Export to EndNote
Pauciullo P, Giannino A, De Michele M, Gentile M, Liguori R, Argiriou A, Carlotto A, Faccenda F, Mancini M, Bond MG, De Simone V, Rubba P
* Increased carotid artery intima-media thickness is associated with a novel mutation of low-density lipoprotein receptor independently of major cardiovascular risk factors (705 views)
Metab Clin Exp (ISSN: 0026-0495, 1532-8600), 2003; 52(11): 1433-1438.
Impact Factor: 2.013
View Export to BibTeX Export to EndNote
Varrone A, Pappata S, Caracò C, Soricelli A, Milan G, Quarantelli M, Alfano B, Postiglione A, Salvatore M
* Voxel-based comparison of rCBF SPET images in frontotemporal dementia and Alzheimer's disease highlights the involvement of different cortical networks (474 views) (PDF 309 views)
Eur J Nucl Med (ISSN: 0340-6997, 1619-7070, 1619-7089), 2002 Nov; 29(11): 1447-1454.
Impact Factor: 3.568
View Export to BibTeX Export to EndNote
Colao A, Spinelli L, Cuocolo A, Spiezia S, Pivonello R, Di Somma C, Bonaduce D, Salvatore M, Lombardi G
* Cardiovascular consequences of early-onset growth hormone excess (422 views)
J Clin Endocrinol Metab (ISSN: 0021-972x), 2002 Jul; 87(7): 3097-3104.
Impact Factor: 5.199
View Export to BibTeX Export to EndNote
Meyer Lindenberg A, Miletich RS, Kohn PD, Esposito G, Carson RE, Quarantelli M, Weinberger DR, Berman KF
* Reduced prefrontal activity predicts exaggerated striatal dopaminergic function in schizophrenia (921 views)
Nat Neurosci (ISSN: 1097-6256), 2002 Mar; 5(3): 267-271.
Impact Factor: 14.857
View Export to BibTeX Export to EndNote
Varrone A, Soricelli A, Postiglione A, Salvatore M
Comparison between cortical distribution of I-123 lomazenil and Tc-99m HMPAO in patients with Alzheimer's disease using SPECT (315 views)
Clin Nucl Med (ISSN: 0363-9762, 1536-0229, 1536-0229electronic), 1999 Sep; 24(9): 660-665.
Impact Factor: 0.253
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De Michele G, Mainenti PP, Soricelli A, Di Salle F, Salvatore E, Longobardi MR, Postiglione A, Salvatore M, Filla A
Cerebral blood flow in spinocerebellar degenerations: a single photon emission tomography study in 28 patients (260 views)
J Neurol (ISSN: 0340-5354, 1432-1459, 1432-1459electronic), 1998 Sep; 245(9): 603-608.
Impact Factor: 2.3
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Postiglione A, Soricelli A, Grossi D, Romano M, Mainenti PP, Ruocco A, Fragrassi N, Chiacchio L, Milan G, De Chiara S, Brunetti A
Changes in cerebral blood flow during cognitive activation evaluated by single photon emission computed tomography in patients with Alzheimer's disease (449 views)
Alzheimer S Res (ISSN: 1356-918x), 1997 Jun; 3(3): 93-99.
Impact Factor: 0
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Iaccarino V, Tedeschi E, Brunetti A, Soricelli A, Salvatore M
Congenital agenesis/aplasia of the internal carotid arteries: MRA and SPECT findings (212 views)
J Comput Assisted Tomogr (ISSN: 0363-8715), 1995 Nov; 19(6): 987-990.
Impact Factor: 1.263
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Soricelli A, Postiglione A, Cuocolo A, De Chiara S, Ruocco A, Brunetti A, Salvatore M, Ell PJ
EFFECT OF ADENOSINE ON CEREBRAL BLOOD-FLOW AS EVALUATED BY SINGLE-PHOTON EMISSION COMPUTED-TOMOGRAPHY IN NORMAL SUBJECTS AND IN PATIENTS WITH OCCLUSIVE CAROTID DISEASE - A COMPARISON WITH ACETAZOLAMIDE (256 views)
Stroke (ISSN: 0039-2499), 1995 Sep; 26(9): 1572-1576.
Impact Factor: 4.323
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Ferrara LA, Mancini M, Iannuzzi R, Marotta T, Gaeta I, Pasanisi F, Postiglione A, Guida L
CAROTID DIAMETER AND BLOOD-FLOW VELOCITIES IN CEREBRAL-CIRCULATION IN HYPERTENSIVE PATIENTS (280 views)
Stroke (ISSN: 0039-2499), 1995 Mar; 26(3): 418-421.
Impact Factor: 4.323
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Ferrara LA, Mancini M, Celentano A, Galderisi M, Iannuzzi R, Marotta T, Gaeta I
Early changes of the arterial carotid wall in uncomplicated primary hypertensive patients: Study by ultrasound high-resolution B-mode imaging (284 views)
Arterioscler Thromb Vasc Biol Arteriosclerosis Thrombosis And Vascular Biology (ISSN: 1079-5642, 1049-8834), 1994 Sep; 14(8): 1290-1296.
Impact Factor: 5.317
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Miletich RS, Quarantelli M, Di Chiro G
REGIONAL CEREBRAL BLOOD-FLOW IMAGING WITH TC-99M-BICISATE SPECT IN ASYMMETRIC PARKINSONS-DISEASE - STUDIES WITH AND WITHOUT CHRONIC DRUG-THERAPY (513 views)
Journal Of Cerebral Blood Flow And Metabolism (ISSN: 0271-678x), 1994 Jan; 14: S106-S106.
Impact Factor: 5.836
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Postiglione A, Soricelli A, Cicerano U, Mansi L, De Chiara S, Gallotta G, Schettini G, Salvatore M
Effect of acute administration of l-acetyl carnitine on cerebral blood flow in patients with chronic cerebral infarct (364 views)
Pharmacol Res (ISSN: 1043-6618, 1096-1186electronic, 1043-6618linking), 1991 Apr; 23(3): 241-246.
Impact Factor: 0.47
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Grossi D, Trojano L, Chiacchio L, Soricelli A, Mansi L, Postiglione A, Salvatore M
Mixed transcortical aphasia: Clinical features and neuroanatomical correlates. A possible role of the right hemisphere (403 views)
Eur Neurol (ISSN: 0014-3022), 1991; 31(4): 204-211.
Impact Factor: 1.22
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Mancini M, De Chiara S, Ferrara LA, Gallotta G, Postiglione A
TRANSCRANIAL DOPPLER EVALUATION OF CEREBROVASCULAR REACTIVITY TO ACETAZOLAMIDE IN NORMAL SUBJECTS (665 views)
15th World Congress Angiology Rome, 1989; 20(4): 284-284.
Impact Factor: 0
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Mancini M, Ferrara LA
Transcranial Doppler Evaluation Of Middle Cerebral Artery In Patients With Carotid Artery Stenosis (255 views)
Progress In Angiology Eds Minerva Medica Torino, 1988; N/D: 73-74.
Impact Factor: 0
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42 Records (36 excluding Abstracts).
Total impact factor: 137.947 (124.834 excluding Abstracts).
Total 5 year impact factor: 148.827 (135.788 excluding Abstracts).
Total impact factor: 137.947 (124.834 excluding Abstracts).
Total 5 year impact factor: 148.827 (135.788 excluding Abstracts).
419 views. Last view on Sunday 21 May 2023, 13:06:41
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