Thalamic activation and cortical deactivation during typical absence status monitored using [18F]FDG-PET: a case report(534 views) Bilo L, Meo R, de Leva MF, Vicidomini C, Salvatore M, Pappata S
Epilepsy Center, Department of Neurological Sciences, Federico II University, Naples, Italy. ledabilo@fastwebnet.it
Neurology Outpatients Service, Azienda Sanitaria Locale Napoli 1, Naples, Italy
Institute of Biostructure and Bioimaging, CNR, Department of Biomorphological Sciences, Naples, Italy
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Thalamic activation and cortical deactivation during typical absence status monitored using [18F]FDG-PET: a case report
We describe the ictal [(18)F]FDG-PET study of a case of absence status showing bilateral thalamic hypermetabolism and frontal cortex hypometabolism. This is the first ictal assessment of absence status by [(18)F]FDG-PET reporting this particular cortical and subcortical involvement. Our findings support the theory of corticothalamic circuitry involvement in the pathophysiology of absence seizures and stress the similarities of the clinical and metabolic pattern observed during absences with the pattern of task-induced interruption of the default state of brain function. (c) 2010 British Epilepsy Association. Published by Elsevier Ltd. All rights reserved.
Thalamic activation and cortical deactivation during typical absence status monitored using [18F]FDG-PET: a case report
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Thalamic activation and cortical deactivation during typical absence status monitored using [18F]FDG-PET: a case report