Estimation of coronary flow reserve by sestamibi imaging in type 2 diabetic patients with normal coronary arteries (322 views)
J Nucl Cardiol (ISSN: 1532-6551, 1071-3581, 1532-6551electronic), 2007 Apr; 14(2): 194-199.
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Paper type: Journal Article,
Impact factor: 2.359, 5-year impact factor: 2.269
Url: http://www.scopus.com/inward/record.url?eid=2-s2.0-33947434096&partnerID=40&md5=cab1729deb7066ce61067b74a337f9ff
Keywords: Coronary Flow Reserve, Single Photon Emission Computed Tomography Imaging, Type 2 Diabetes Mellitus, Angiotensin 2 Receptor Antagonist, Antidiabetic Agent, Dipeptidyl Carboxypeptidase Inhibitor, Dipyridamole, Methoxy Isobutyl Isonitrile Technetium Tc 99m, Adult, Angiocardiography, Article, Blood Flow Velocity, Clinical Article, Controlled Study, Coronary Artery Blood Flow, Coronary Artery Disease, Coronary Artery Pressure, Diabetic Patient, Diagnostic Value, Exercise Test, Female, Human, Image Analysis, Image Display, Image Quality, Non Insulin Dependent Diabetes Mellitus, Priority Journal, Pulmonary Artery, Single Photon Emission Computer Tomography, Coronary Arteriosclerosis, Coronary Vessels, Diabetic Angiopathies, Image Interpretation, Computer-Assisted, Middle Aged, Radiopharmaceuticals, Risk Assessment, Technetium Tc 99m Sestamibi, Vasodilator Agents,
Affiliations:
*** IBB - CNR ***
Department of Biomorphological and Functional Sciences, University Federico II, Naples, Italy.
Department of Clinical Medicine, Cardiovascular and Immunological Sciences, University Federico II, Naples, Italy
Institute of Biostructure and Bioimages, National Council of Research, Naples, Italy
SDN Foundation, Institute of Diagnostic and Nuclear Development, Naples, Italy
References:
Grundy, S.M., Benjamin, I.J., Burke, G.L., Chait, A., Eckel, R.H., Howard, B.V., Diabetes and cardiovascular disease: a statement for healthcare professionals from the American Heart Association (1999) Circulation, 100, pp. 1134-114
Laakso, M., Glycemic control and the risk for coronary heart disease in patients with non-insulin-dependent diabetes mellitus. The Finnish studies (1996) Ann Intern Med, 124, pp. 127-130
Nitenberg, A., Valensi, P., Sachs, R., Dalim, M., Aptecar, E., Attali, J.R., Impairment of coronary vascular reserve and Ach-induced coronary vasodilatation in diabetic patients with angiographically normal coronary arteries and normal ventricular systolic function (1993) Diabetes, 32, pp. 1017-1023
Nahser, P.J., Brown, R.E., Oskarsson, H., Winnifold, M.D., Rossen, J.D., Maximal coronary flow reserve and metabolic coronary vasodilatation in patients with diabetes mellitus (1995) Circulation, 91, pp. 635-640
Mintz, G.S., Painter, J.A., Pichard, A.D., Kent, K.M., Satler, L.F., Popma, J.J., Atherosclerosis in angiographically "normal" coronary artery reference segments: an intravascular ultrasound study with clinical correlations (1995) J Am Coll Cardiol, 25, pp. 1479-1485
Yarom, R., Zirkin, H., Stammler, G., Rose, A.G., Human coronary microvessels in diabetes and ischaemia. Morphometric study of autopsy material (1992) J Pathol, 166, pp. 265-270
Meyer, C., Schwaiger, M., Myocardial blood flow and glucose metabolism in diabetes mellitus (1997) Am J Cardiol, 80, pp. 94A-101A
Di Carli, M.F., Janisse, J., Grunberger, G., Ager, J., Role of chronic hyperglycemia in the pathogenesis of coronary microvascular dysfunction in diabetes (2003) J Am Coll Cardiol, 41, pp. 1387-1393
Pitkanen, O.P., Nuutila, P., Raitakari, O.T., Ronnemaa, T., Koskinen, P.J., Iida, H., Coronary flow reserve is reduced in young men with IDDM (1998) Diabetes, 47, pp. 248-254
Srinivasan, M., Herrero, P., McGill, J.B., Bennik, J., Heere, B., Lesniak, D., The effects of plasma insulin and glucose on myocardial blood flow in patients with type 1 diabetes mellitus (2005) J Am Coll Cardiol, 46, pp. 42-48
Yokoyama, I., Yonekura, K., Ohtake, T., Yang, W., Shin, W.S., Yamada, N., Coronary microangiopathy in type 2 diabetic patients: relation to glycemic control, sex, and microvascular angina rather than to coronary artery disease (2000) J Nucl Med, 41, pp. 978-985
Bergmann, S.R., Fox, K.A., Rand, A.L., McElvany, K.D., Welch, M.J., Markham, J., Quantification of regional myocardial blood flow in vivo with H2-15O (1984) Circulation, 70, pp. 724-733
Araujo, L.I., Lammertsma, A.A., Rhodes, C.G., McFalls, E.O., Iida, H., Rechavia, E., Noninvasive quantification of regional myocardial blood flow in coronary artery disease with oxygen-15-labeled carbon dioxide inhalation and positron emission tomography (1991) Circulation, 83, pp. 875-885
Hutchins, G., Schwaiger, M., Rosenspire, K.C., Krivokapitch, J., Schelbert, H.R., Kuhl, D.E., Noninvasive quantification of regional myocardial blood flow with N-13 ammonia and dynamic positron emission tomographic imaging (1990) J Am Coll Cardiol, 15, pp. 1032-1042
Schelbert, H.R., Phelps, M.E., Huang SC MacDonald, N.S., Hansen, H., Selin, C., N-13 ammonia as an indicator of myocardial blood flow (1981) Circulation, 63, pp. 1259-1272
Sugihara, H., Yonekura, Y., Kataoka, K., Fukai, D., Kitamura, N., Taniguchi, Y., Estimation of coronary flow reserve with the use of dynamic planar and SPECT images of Tc-99m tetrofosmin (2001) J Nucl Cardiol, 8, pp. 575-579
Storto, G., Cirillo, P., Vicario, M.L., Pellegrino, T., Sorrentino, A.R., Petretta, M., Estimation of coronary flow reserve by Tc-99m sestamibi imaging in patients with coronary artery disease: comparison with the results of intracoronary Doppler technique (2004) J Nucl Cardiol, 11, pp. 682-688
Devereux, R.B., Reichek, N., Echocardiographic determination of left ventricular mass in man. Anatomic validation of the method (1977) Circulation, 55, pp. 613-618
Vicario, M.L., Cirillo, L., Storto, G., Pellegrino, T., Ragone, N., Fontanella, L., Influence of risk factors on coronary flow reserve in patients with 1-vessel coronary artery disease (2005) J Nucl Med, 46, pp. 1438-1443
Acampa, W., Spinelli, L., Petretta, M., De Lauro, F., Ibello, F., Cuocolo, A., Prognostic value of myocardial ischemia in patients with uncomplicated acute myocardial infarction: direct comparison of stress echocardiography and myocardial perfusion imaging (2005) J Nucl Med, 46, pp. 417-423
Sundell, J., Janatuinen, T., Ronnemaa, T., Raitakari, O.T., Toikka, J., Nuutila, P., Diabetic background retinopathy is associated with impaired coronary vasoreactivity in people with Type 1 diabetes (2004) Diabetologia, 47, pp. 725-731
de Silva, R., Camici, P.G., Role of positron emission tomography in the investigation of human coronary circulatory function (1994) Cardiovasc Res, 28, pp. 1595-1612
Taki, J., Fujino, S., Nakajima, K., Matsunari, I., Okazaki, H., Saga, T., Tc-99m sestamibi retention characteristics during pharmacological hyperemia in human myocardium: comparison with coronary flow reserve measured by Doppler flowire (2001) J Nucl Med, 42, pp. 1457-1463
Ito, Y., Katoh, C., Noriyasu, K., Kuge, Y., Furuyama, H., Morita, K., Estimation of myocardial blood flow and myocardial flow reserve by 99mTc-sestamibi imaging: comparison with the results of O-15 H2O PET (2003) Eur J Nucl Med Mol Imaging, 30, pp. 281-287
Smits, P., Williams, S.B., Lipson, D.E., Banitt, P., Rongen, G.A., Creager, M.A., Endothelial release of nitric oxide contributes to the vasodilator effect of adenosine in humans (1995) Circulation, 92, pp. 2135-2141
Buus, N.H., Bottcher, M., Hermansen, F., Sander, M., Nielsen, T.T., Mulvany, M.J., Influence of nitric oxide synthase and adrenergic inhibition on adenosine-induced myocardial hyperemia (2001) Circulation, 104, pp. 2305-2310
Czernin, J., Porenta, G., Brunken, R., Krivokapich, J., Chen, K., Bennett, R., Influence of age and hemodynamics on myocardial blood flow and flow reserve (1993) Circulation, 88, pp. 62-69
J Nucl Cardiol (ISSN: 1532-6551, 1071-3581, 1532-6551electronic), 2007 Apr; 14(2): 194-199.
Export to BibTeX Export to EndNote
Paper type: Journal Article,
Impact factor: 2.359, 5-year impact factor: 2.269
Url: http://www.scopus.com/inward/record.url?eid=2-s2.0-33947434096&partnerID=40&md5=cab1729deb7066ce61067b74a337f9ff
Keywords: Coronary Flow Reserve, Single Photon Emission Computed Tomography Imaging, Type 2 Diabetes Mellitus, Angiotensin 2 Receptor Antagonist, Antidiabetic Agent, Dipeptidyl Carboxypeptidase Inhibitor, Dipyridamole, Methoxy Isobutyl Isonitrile Technetium Tc 99m, Adult, Angiocardiography, Article, Blood Flow Velocity, Clinical Article, Controlled Study, Coronary Artery Blood Flow, Coronary Artery Disease, Coronary Artery Pressure, Diabetic Patient, Diagnostic Value, Exercise Test, Female, Human, Image Analysis, Image Display, Image Quality, Non Insulin Dependent Diabetes Mellitus, Priority Journal, Pulmonary Artery, Single Photon Emission Computer Tomography, Coronary Arteriosclerosis, Coronary Vessels, Diabetic Angiopathies, Image Interpretation, Computer-Assisted, Middle Aged, Radiopharmaceuticals, Risk Assessment, Technetium Tc 99m Sestamibi, Vasodilator Agents,
Affiliations:
*** IBB - CNR ***
Department of Biomorphological and Functional Sciences, University Federico II, Naples, Italy.
Department of Clinical Medicine, Cardiovascular and Immunological Sciences, University Federico II, Naples, Italy
Institute of Biostructure and Bioimages, National Council of Research, Naples, Italy
SDN Foundation, Institute of Diagnostic and Nuclear Development, Naples, Italy
References:
Grundy, S.M., Benjamin, I.J., Burke, G.L., Chait, A., Eckel, R.H., Howard, B.V., Diabetes and cardiovascular disease: a statement for healthcare professionals from the American Heart Association (1999) Circulation, 100, pp. 1134-114
Laakso, M., Glycemic control and the risk for coronary heart disease in patients with non-insulin-dependent diabetes mellitus. The Finnish studies (1996) Ann Intern Med, 124, pp. 127-130
Nitenberg, A., Valensi, P., Sachs, R., Dalim, M., Aptecar, E., Attali, J.R., Impairment of coronary vascular reserve and Ach-induced coronary vasodilatation in diabetic patients with angiographically normal coronary arteries and normal ventricular systolic function (1993) Diabetes, 32, pp. 1017-1023
Nahser, P.J., Brown, R.E., Oskarsson, H., Winnifold, M.D., Rossen, J.D., Maximal coronary flow reserve and metabolic coronary vasodilatation in patients with diabetes mellitus (1995) Circulation, 91, pp. 635-640
Mintz, G.S., Painter, J.A., Pichard, A.D., Kent, K.M., Satler, L.F., Popma, J.J., Atherosclerosis in angiographically "normal" coronary artery reference segments: an intravascular ultrasound study with clinical correlations (1995) J Am Coll Cardiol, 25, pp. 1479-1485
Yarom, R., Zirkin, H., Stammler, G., Rose, A.G., Human coronary microvessels in diabetes and ischaemia. Morphometric study of autopsy material (1992) J Pathol, 166, pp. 265-270
Meyer, C., Schwaiger, M., Myocardial blood flow and glucose metabolism in diabetes mellitus (1997) Am J Cardiol, 80, pp. 94A-101A
Di Carli, M.F., Janisse, J., Grunberger, G., Ager, J., Role of chronic hyperglycemia in the pathogenesis of coronary microvascular dysfunction in diabetes (2003) J Am Coll Cardiol, 41, pp. 1387-1393
Pitkanen, O.P., Nuutila, P., Raitakari, O.T., Ronnemaa, T., Koskinen, P.J., Iida, H., Coronary flow reserve is reduced in young men with IDDM (1998) Diabetes, 47, pp. 248-254
Srinivasan, M., Herrero, P., McGill, J.B., Bennik, J., Heere, B., Lesniak, D., The effects of plasma insulin and glucose on myocardial blood flow in patients with type 1 diabetes mellitus (2005) J Am Coll Cardiol, 46, pp. 42-48
Yokoyama, I., Yonekura, K., Ohtake, T., Yang, W., Shin, W.S., Yamada, N., Coronary microangiopathy in type 2 diabetic patients: relation to glycemic control, sex, and microvascular angina rather than to coronary artery disease (2000) J Nucl Med, 41, pp. 978-985
Bergmann, S.R., Fox, K.A., Rand, A.L., McElvany, K.D., Welch, M.J., Markham, J., Quantification of regional myocardial blood flow in vivo with H2-15O (1984) Circulation, 70, pp. 724-733
Araujo, L.I., Lammertsma, A.A., Rhodes, C.G., McFalls, E.O., Iida, H., Rechavia, E., Noninvasive quantification of regional myocardial blood flow in coronary artery disease with oxygen-15-labeled carbon dioxide inhalation and positron emission tomography (1991) Circulation, 83, pp. 875-885
Hutchins, G., Schwaiger, M., Rosenspire, K.C., Krivokapitch, J., Schelbert, H.R., Kuhl, D.E., Noninvasive quantification of regional myocardial blood flow with N-13 ammonia and dynamic positron emission tomographic imaging (1990) J Am Coll Cardiol, 15, pp. 1032-1042
Schelbert, H.R., Phelps, M.E., Huang SC MacDonald, N.S., Hansen, H., Selin, C., N-13 ammonia as an indicator of myocardial blood flow (1981) Circulation, 63, pp. 1259-1272
Sugihara, H., Yonekura, Y., Kataoka, K., Fukai, D., Kitamura, N., Taniguchi, Y., Estimation of coronary flow reserve with the use of dynamic planar and SPECT images of Tc-99m tetrofosmin (2001) J Nucl Cardiol, 8, pp. 575-579
Storto, G., Cirillo, P., Vicario, M.L., Pellegrino, T., Sorrentino, A.R., Petretta, M., Estimation of coronary flow reserve by Tc-99m sestamibi imaging in patients with coronary artery disease: comparison with the results of intracoronary Doppler technique (2004) J Nucl Cardiol, 11, pp. 682-688
Devereux, R.B., Reichek, N., Echocardiographic determination of left ventricular mass in man. Anatomic validation of the method (1977) Circulation, 55, pp. 613-618
Vicario, M.L., Cirillo, L., Storto, G., Pellegrino, T., Ragone, N., Fontanella, L., Influence of risk factors on coronary flow reserve in patients with 1-vessel coronary artery disease (2005) J Nucl Med, 46, pp. 1438-1443
Acampa, W., Spinelli, L., Petretta, M., De Lauro, F., Ibello, F., Cuocolo, A., Prognostic value of myocardial ischemia in patients with uncomplicated acute myocardial infarction: direct comparison of stress echocardiography and myocardial perfusion imaging (2005) J Nucl Med, 46, pp. 417-423
Sundell, J., Janatuinen, T., Ronnemaa, T., Raitakari, O.T., Toikka, J., Nuutila, P., Diabetic background retinopathy is associated with impaired coronary vasoreactivity in people with Type 1 diabetes (2004) Diabetologia, 47, pp. 725-731
de Silva, R., Camici, P.G., Role of positron emission tomography in the investigation of human coronary circulatory function (1994) Cardiovasc Res, 28, pp. 1595-1612
Taki, J., Fujino, S., Nakajima, K., Matsunari, I., Okazaki, H., Saga, T., Tc-99m sestamibi retention characteristics during pharmacological hyperemia in human myocardium: comparison with coronary flow reserve measured by Doppler flowire (2001) J Nucl Med, 42, pp. 1457-1463
Ito, Y., Katoh, C., Noriyasu, K., Kuge, Y., Furuyama, H., Morita, K., Estimation of myocardial blood flow and myocardial flow reserve by 99mTc-sestamibi imaging: comparison with the results of O-15 H2O PET (2003) Eur J Nucl Med Mol Imaging, 30, pp. 281-287
Smits, P., Williams, S.B., Lipson, D.E., Banitt, P., Rongen, G.A., Creager, M.A., Endothelial release of nitric oxide contributes to the vasodilator effect of adenosine in humans (1995) Circulation, 92, pp. 2135-2141
Buus, N.H., Bottcher, M., Hermansen, F., Sander, M., Nielsen, T.T., Mulvany, M.J., Influence of nitric oxide synthase and adrenergic inhibition on adenosine-induced myocardial hyperemia (2001) Circulation, 104, pp. 2305-2310
Czernin, J., Porenta, G., Brunken, R., Krivokapich, J., Chen, K., Bennett, R., Influence of age and hemodynamics on myocardial blood flow and flow reserve (1993) Circulation, 88, pp. 62-69
Estimation of coronary flow reserve by sestamibi imaging in type 2 diabetic patients with normal coronary arteries
BACKGROUND: We assessed coronary flow reserve (CFR) by sestamibi imaging in patients with type 2 diabetes without coronary artery disease and normal coronary vessels.; METHODS AND RESULTS: Dipyridamole/rest technetium 99m sestamibi imaging was performed in 33 patients with type 2 diabetes without a history of coronary artery disease and normal coronary vessels at angiography and in 12 control subjects. Myocardial blood flow (MBF) was estimated by measuring first-transit counts in the pulmonary artery and myocardial counts from tomographic images. Estimated CFR was expressed as the ratio of stress MBF to rest MBF. Rest MBF and CFR were corrected for rate-pressure product and expressed as normalized MBF and normalized CFR. At rest, estimated MBF and normalized MBF were not different in control subjects versus patients (0.98 +/- 0.4 counts x pixel(-1) x s(-1) vs 1.42 +/- 0.9 counts x pixel(-1) x s(-1) and 1.14 +/- 0.5 counts x pixel(-1) x s(-1) vs 1.61 +/- 0.9 counts x pixel(-1) x s(-1), respectively). Conversely, stress MBF was higher in control subjects than in patients (2.34 +/- 0.8 counts x pixel(-1) x s(-1) vs 1.55 +/- 0.8 counts.pixel(-1) x s(-1), P < .01). Thus estimated CFR was higher in control subjects than in patients (2.40 +/- 0.3 vs 1.36 +/- 0.8, P < .0001). After correction for the rate-pressure product, normalized CFR was still higher in control subjects than in patients (2.10 +/- 0.5 vs 1.28 +/- 0.8, P < .001).; CONCLUSIONS: Sestamibi imaging may detect impaired coronary vascular function in response to dipyridamole in type 2 diabetic patients without a history of coronary artery disease and with normal coronary arteries.
BACKGROUND: We assessed coronary flow reserve (CFR) by sestamibi imaging in patients with type 2 diabetes without coronary artery disease and normal coronary vessels.; METHODS AND RESULTS: Dipyridamole/rest technetium 99m sestamibi imaging was performed in 33 patients with type 2 diabetes without a history of coronary artery disease and normal coronary vessels at angiography and in 12 control subjects. Myocardial blood flow (MBF) was estimated by measuring first-transit counts in the pulmonary artery and myocardial counts from tomographic images. Estimated CFR was expressed as the ratio of stress MBF to rest MBF. Rest MBF and CFR were corrected for rate-pressure product and expressed as normalized MBF and normalized CFR. At rest, estimated MBF and normalized MBF were not different in control subjects versus patients (0.98 +/- 0.4 counts x pixel(-1) x s(-1) vs 1.42 +/- 0.9 counts x pixel(-1) x s(-1) and 1.14 +/- 0.5 counts x pixel(-1) x s(-1) vs 1.61 +/- 0.9 counts x pixel(-1) x s(-1), respectively). Conversely, stress MBF was higher in control subjects than in patients (2.34 +/- 0.8 counts x pixel(-1) x s(-1) vs 1.55 +/- 0.8 counts.pixel(-1) x s(-1), P < .01). Thus estimated CFR was higher in control subjects than in patients (2.40 +/- 0.3 vs 1.36 +/- 0.8, P < .0001). After correction for the rate-pressure product, normalized CFR was still higher in control subjects than in patients (2.10 +/- 0.5 vs 1.28 +/- 0.8, P < .001).; CONCLUSIONS: Sestamibi imaging may detect impaired coronary vascular function in response to dipyridamole in type 2 diabetic patients without a history of coronary artery disease and with normal coronary arteries.
Estimation of coronary flow reserve by sestamibi imaging in type 2 diabetic patients with normal coronary arteries
| ▼ Noninvasive techniques for coronary flow reserve assessment |
Estimation of coronary flow reserve by sestamibi imaging in type 2 diabetic patients with normal coronary arteries
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Eur J Nucl Med (ISSN: 1619-7070, 1619-7089, 0340-6997), 2010 Oct; 37: N/D-N/D.
Impact Factor: 5.036
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Cuocolo A, Petretta M, Soricelli A
* Measurement of coronary flow reserve by noninvasive cardiac imaging (248 views)
Eur J Nucl Med (ISSN: 1619-7089, 1619-7070, 0340-6997), 2010 Jun; 37(6): 1198-1202.
Impact Factor: 5.036
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Storto G, Soricelli A, Pellegrino T, Petretta M, Cuocolo A
* Assessment of the arterial input function for estimation of coronary flow reserve by single photon emission computed tomography: comparison of two different approaches (1958 views)
Eur J Nucl Med (ISSN: 1619-7089, 1619-7070, 0340-6997), 2009 Dec; 36(12): 2034-2041.
Impact Factor: 4.531
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Storto G, Mainolfi C, Caprio MG, Pellegrino T, Cicala S, Grieco M, De Leva F, Cuocolo A
* Noninvasive Measurement of Coronary Flow Reserve by Tc-99m Sestamibi Imaging in Children With Kawasaki Disease (267 views)
Eur J Nucl Med (ISSN: 1619-7070, 1619-7089, 0340-6997), 2009 Sep; 36: N/D-N/D.
Impact Factor: 4.531
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Storto G, Pellegrino T, Vassallo S, De Marino M, De Falco T, Punzo G, Petretta A, Cuocolo A
* Assessment of the Arterial Input Function for the Estimation of Coronary Flow Reserve by SPECT Imaging: Comparison of Two Different Methods (321 views)
Eur J Nucl Med (ISSN: 1619-7070, 1619-7089, 0340-6997), 2008 Oct; 35: N/D-N/D.
Impact Factor: 4.532
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Petretta M, Costanzo P, Acampa W, Imbriaco M, Ferro A, Filardi PP, Cuocolo A
* Noninvasive assessment of coronary anatomy and myocardial perfusion: Going toward an integrated imaging approach (343 views)
J Cardiovasc Med (ISSN: 1558-2027, 1558-2035), 2008 Oct; 9(10): 977-986.
Impact Factor: 1.407
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Sciacca MFM, Pappalardo M, Milardi D, Grasso DM, La Rosa C
* Calcium-Activated Membrane Interaction Of The Islet Amyloid Polypeptide: Implications In The Pathogenesis Of Type Ii Diabetes Mellitus (962 views)
Arch Biochem Biophys, 2008 Sep 15; 65(1-2): 291-298.
Impact Factor: 3.043
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Storto G, Sorrentino AR, Pellegrino T, Liuzzi R, Petretta M, Cuocolo A
* Assessment of coronary flow reserve by sestamibi imaging in patients with typical chest pain and normal coronary arteries (vol 34, pg 1156, 2007) (284 views)
Eur J Nucl Med (ISSN: 1619-7070, 1619-7089, 0340-6997), 2008 Sep; 35(9): N/D-N/D.
Impact Factor: 4.532
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Petretta M, Soricelli A, Storto G, Cuocolo A
* Assessment of coronary flow reserve using single photon emission computed tomography with technetium 99m-labeled tracers (416 views)
J Nucl Cardiol (ISSN: 1532-6551, 1071-3581, 1532-6551electronic), 2008 May; 15(3): 456-465.
Impact Factor: 2.442
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Petretta M, Acampa W, Evangelista L, Daniele S, Ferro A, Cuocolo A
* Impact of inducible ischemia by stress SPECT in cardiac risk assessment in diabetic patients: Rationale and design of a prospective, multicenter trial (308 views)
J Nucl Cardiol (ISSN: 1071-3581, 1532-6551, 1532-6551electronic), 2008 Jan; 15(1): 100-104.
Impact Factor: 2.442
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Storto G, Sorrentino AR, Pellegrino T, Liuzzi R, Petretta M, Cuocolo A
* Assessment of coronary flow reserve by sestamibi imaging in patients with typical chest pain and normal coronary arteries (355 views)
Eur J Nucl Med (ISSN: 1619-7070, 1619-7089, 0340-6997), 2007 Sep; 34(8): 1156-1161.
Impact Factor: 4.101
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Storto G, Sorrentino AR, Pellegrino T, Liuzzi R, Peretta M, Cuocolo A
* Coronary Flow Reserve By Sistemibi Imaging In Patients With Typical Chest Pain And Normal Coronary Arteries (255 views)
European Journal Of Nuclear Medicine And Molecular Imaging, 2006; 0: N/D-N/D.
Impact Factor: 5.217
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Palmieri V, Storto G, Arezzi E, Pellegrino T, Mancini M, Di Minno G, Ferrara AL, Cuocolo A, Celentano A
* Relations of left ventricular mass and systolic function to endothelial function and coronary flow reserve in healthy, new discovered hypertensive subjects (311 views)
J Hum Hypertens (ISSN: 0950-9240), 2005 Dec; 19(12): 941-950.
Impact Factor: 2.405
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Pellegrino T, Storto G, Filardi PP, Sorrentino AR, Silvestro A, Petretta M, Brevetti G, Chiariello M, Salvatore M, Cuocolo A
* Relationship between brachial artery flow-mediated dilation and coronary flow reserve in patients with peripheral artery disease (330 views)
J Nucl Med (ISSN: 0161-5505, 1535-5667, 1535-5667electronic), 2005 Dec; 46(12): 1997-2002.
Impact Factor: 4.684
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Vicario MLE, Cirillo L, Storto G, Pellegrino T, Ragone N, Fontanella L, Petretta M, Bonaduce D, Cuocolo A
* Influence of risk factors on coronary flow reserve in patients with 1-vessel coronary artery disease (350 views)
J Nucl Med (ISSN: 0161-5505, 1535-5667, 1535-5667electronic), 2005 Sep; 46(9): 1438-1443.
Impact Factor: 4.684
View Export to BibTeX Export to EndNote
Storto G, Vicario MLE, Pellegrino T, Cirillo L, Ragone N, Fontanella L, Petretta M, Bonaduce D, Cuocolo A
* Influence of Risk Factors on Tc-99m Sestamibi Estimated Coronary Flow Reserve in Patients with One-vessel Coronary Artery Disease (227 views)
Eur J Nucl Med (ISSN: 1619-7070, 1619-7089, 0340-6997), 2005 Sep; 32: N/D-N/D.
Impact Factor: 3.883
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Perrone-Filardi P, Silvestro A, Pellegrino T, Brevetti G, Corrado L, Cafiero M, Chiariello M, Cuocolo A
* Relation between coronary flow reserve and flow mediated dilation index in patients with peripheral artery disease (237 views)
European Heart Journal (ISSN: 0195-668x), 2005 Sep; 26: N/D-N/D.
Impact Factor: 7.341
View Export to BibTeX Export to EndNote
Pellegrino T, Storto G, Sorrentino AR, Filardi PP, Silvestri A, Petretta M, Brevetti G, Cuocolo A
* Relation Between Tc-99m Sestamibi Estimated Coronary Flow Reserve and Flow Mediated Dilation Index in Patients with Peripheral Artery Disease (238 views)
Eur J Nucl Med (ISSN: 1619-7070, 1619-7089, 0340-6997), 2005 Sep; 32: N/D-N/D.
Impact Factor: 3.883
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Storto G, Cirillo P, Eufrasia Vicario ML, Pellegrino T, Sorrentino AR, Petretta M, Galasso G, De Sanctis V, Piscione F, Cuocolo A
* Estimation of coronary flow reserve by Tc-99m sestamibi imaging in patients with coronary artery disease: Comparison with the results of intracoronary Doppler technique (421 views)
J Nucl Cardiol (ISSN: 1071-3581, 1532-6551, 1532-6551electronic), 2004 Nov; 11(6): 682-688.
Impact Factor: 1.849
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Storto G, Pellegrino T, Cirillo P, Sorrentino A, Galasso G, Piscione F, Salvatore M, Cuocolo A
* Estimation of coronary flow reserve by Tc-99m sestamibi imaging in patients with coronary artery disease: Comparison with the results of intracoronary Doppler technique (265 views)
Eur J Nucl Med (ISSN: 1619-7070, 1619-7089, 0340-6997), 2004 Sep; 31: N/D-N/D.
Impact Factor: 3.935
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* Prognostic value of coronary flow reserve in patients with suspected or known coronary artery disease referred to PET myocardial perfusion imaging: A meta-analysis (101 views)
J Nucl Cardiol (ISSN: 1071-3581linking, 1532-6551electronic), 2021 Jun; 28(3): 904-918.
Impact Factor: 2.811
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Clemente G, Giorgini M, Mancini M, Gallo M, Amd-associazione Medici Diabetologi ‘diabetes Cancer’ worki
* Diabetologists and Oncologists attitudes towards treating diabetes in the oncologic patient: Insights from an exploratory survey (245 views)
Diabetes Res Clin Pract (ISSN: 0168-8227linking), 2018 Sep; 143: 420-427.
Impact Factor: 3.639
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Zampella E, Acampa W, Assante R, Nappi C, Gaudieri V, Mainolfi CG, Green R, Cantoni V, Panico M, Klain M, Petretta M, Slomka PJ, Cuocolo A
* Combined evaluation of regional coronary artery calcium and myocardial perfusion by (82)Rb PET/CT in the identification of obstructive coronary artery disease (460 views)
Eur J Nucl Med (ISSN: 1619-7089electronic, 1619-7070linking, 1619-7070print), 2018 Jan 25; 45(4): 521-529.
Impact Factor: 5.036
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Tumminia A, Milluzzo A, Cinti F, Parisi M, Tata F, Frasca F, Frittitta L, Vigneri R, Sciacca L
* Abnormal 1-hour post-load glycemia during pregnancy impairs post-partum metabolic status: a single-center experience (171 views)
J Endocrinol Invest (ISSN: 1720-8386, 0391-4097, 1720-8386electronic), 2017 Oct 24; N/D: N/D-N/D.
Impact Factor: 3.166
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Assante R, Acampa W, Zampella E, Arumugam P, Nappi C, Gaudieri V, Mainolfi CG, Panico M, Magliulo M, Tonge CM, Petretta M, Cuocolo A
* Prognostic value of atherosclerotic burden and coronary vascular function in patients with suspected coronary artery disease (216 views)
Eur J Nucl Med (ISSN: 1619-7070, 1619-7089, 1619-7070print), 2017 Aug 16; N/D: N/D-N/D.
Impact Factor: 7.704
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Assante R, Acampa W, Zampella E, Arumugam P, Nappi C, Gaudieri V, Panico M, Magliulo M, Tonge CM, Petretta M, Cuocolo A
* Coronary atherosclerotic burden vs. coronary vascular function in diabetic and nondiabetic patients with normal myocardial perfusion: a propensity score analysis (333 views)
Eur J Nucl Med (ISSN: 1619-7070, 1619-7089, 1619-7070print), 2017 Mar 14; N/D: N/D-N/D.
Impact Factor: 7.704
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Assante R, Zampella E, Arumugam P, Acampa W, Imbriaco M, Tout D, Petretta M, Tonge C, Cuocolo A
* Quantitative relationship between coronary artery calcium and myocardial blood flow by hybrid rubidium-82 PET/CT imaging in patients with suspected coronary artery disease (432 views)
J Nucl Cardiol (ISSN: 1071-3581, 1532-6551, 1532-6551electronic), 2017; 24(2): 494-501.
Impact Factor: 4.011
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Monti SM, Supuran CT, De Simone G
* DPP-4 inhibitors: a patent review (2012 - 2014) (573 views)
Expert Opin Ther Pat (ISSN: 1354-3776, 1744-7674electronic), 2015 Feb; 25(2): 209-236.
Impact Factor: 4.626
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Petretta M, Storto G, Pellegrino T, Bonaduce D, Cuocolo A
* Quantitative Assessment of Myocardial Blood Flow with SPECT (380 views)
Prog Cardiovasc Dis (ISSN: 0033-0620), 2015 Jan 3; 57(6): 607-614.
Impact Factor: 4.635
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Coppo C, Bonfanti D, Bo S, Giordanino C, Gallo M, Cococcia S, Ciccone G, Smedile A, Ciancio A, Bugianesi E, Fagoonee S, Pellicano R, Rizzetto M, Saracco GM
* Risk of microangiopathy in type 2 diabetes mellitus patients with or without chronic hepatitis C: Results of a retrospective long-term controlled cohort study (300 views)
Dig Liver Dis (ISSN: 1590-8658, 1590-8658linking), 2015; 47(5): 405-410.
Impact Factor: 2.719
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Storto G, Gallicchio R, Maddalena F, Pellegrino T, Petretta M, Fiumara G, Cuocolo A
* Estimation of coronary flow reserve by sestamibi imaging in patients with mild hypertension and normal coronary arteries (478 views)
Q J Nucl Med Mol Im (ISSN: 1824-4785, 1824-4478, 1827-1936), 2014 Mar 14; 59(3): 336-341.
Impact Factor: 2.033
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Paolillo S, Rengo G, Pagano G, Pellegrino T, Savarese G, Femminella GD, Tuccillo M, Boemio A, Attena E, Formisano R, Petraglia L, Scopacasa F, Galasso G, Leosco D, Trimarco B, Cuocolo A, Perrone-Filardi P
* Impact of diabetes on cardiac sympathetic innervation in patients with heart failure: a 123I meta-iodobenzylguanidine (123I MIBG) scintigraphic study (313 views)
Diabetes Care (ISSN: 1935-5548, 0149-5992), 2013 Sep; 36(8): 2395-2401.
Impact Factor: 8.57
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Marciano C, Galderisi M, Gargiulo P, Acampa W, D'Amore C, Esposito R, Capasso E, Savarese G, Casaretti L, Lo Iudice F, Esposito G, Rengo G, Leosco D, Cuocolo A, Perrone-Filardi P
* Effects of type 2 diabetes mellitus on coronary microvascular function and myocardial perfusion in patients without obstructive coronary artery disease (708 views)
Eur J Nucl Med (ISSN: 1619-7070, 1619-7089, 0340-6997), 2012 Jul; 39(7): 1199-1206.
Impact Factor: 5.114
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Petretta M, Acampa W, Zampella E, Assante R, Petretta MP, Cuocolo R, Fabiani I, Della Rattal GL, Perrone-Filardi P, Cuocolo A
* Imaging techniques for assessment of coronary flow reserve (400 views)
Monaldi Arch Chest Dis Card Ser (ISSN: 1122-0643, 1122-0643print), 2011 Dec; 76(4): 192-197.
Impact Factor: 7.132
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Daniele S, Nappi C, Acampa W, Storto G, Pellegrino T, Ricci F, Xhoxhi E, Porcaro F, Petretta M, Cuocolo A
* Incremental prognostic value of coronary flow reserve assessed with single-photon emission computed tomography (427 views)
J Nucl Cardiol (ISSN: 1071-3581, 1532-6551, 1532-6551electronic), 2011 Sep; 18(4): 612-619.
Impact Factor: 2.668
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Striano P, Caranci F, Pappata S, Zara F, Striano S
* Hemidystonia in uncontrolled type 2 diabetes mellitus (275 views)
Arch Neurol (ISSN: 1538-3687electronic, 0003-9942linking), 2011 May; 68(5): 674-675.
Impact Factor: 7.584
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Bozzetto L, Prinster A, Mancini M, Giacco R, De Natale C, Salvatore M, Riccardi G, Rivellese AA, Annuzzi G
* Liver fat in obesity: role of type 2 diabetes mellitus and adipose tissue distribution (418 views)
Eur J Clin Invest (ISSN: 0014-2972, 1365-2362, 0014-2972linking), 2011 Jan; 41(1): 39-44.
Impact Factor: 3.018
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Cuocolo A, Cittanti C, Acampa W, Larobina M, Petretta M
* Current and Future Status of Blood Flow Tracers (280 views)
Curr Cardiovasc Imaging Rep (ISSN: 1941-9066), 2011; 4(3): 227-236.
Impact Factor: 0
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Pellegrino T, Daniele S, Acampa W, Storto G, Petretta MP, Xhoxhi E, Gallicchio R, Nappi C, Petretta M, Cuocolo A
* Long-Term Prognostic Value of Single-Photon Emission Computed Tomography: Added Value of Coronary Flow Reserve (281 views)
Eur J Nucl Med (ISSN: 1619-7070, 1619-7089, 0340-6997), 2010 Oct; 37: N/D-N/D.
Impact Factor: 5.036
View Export to BibTeX Export to EndNote
Cuocolo A, Petretta M, Soricelli A
* Measurement of coronary flow reserve by noninvasive cardiac imaging (248 views)
Eur J Nucl Med (ISSN: 1619-7089, 1619-7070, 0340-6997), 2010 Jun; 37(6): 1198-1202.
Impact Factor: 5.036
View Export to BibTeX Export to EndNote
Storto G, Soricelli A, Pellegrino T, Petretta M, Cuocolo A
* Assessment of the arterial input function for estimation of coronary flow reserve by single photon emission computed tomography: comparison of two different approaches (1958 views)
Eur J Nucl Med (ISSN: 1619-7089, 1619-7070, 0340-6997), 2009 Dec; 36(12): 2034-2041.
Impact Factor: 4.531
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Storto G, Mainolfi C, Caprio MG, Pellegrino T, Cicala S, Grieco M, De Leva F, Cuocolo A
* Noninvasive Measurement of Coronary Flow Reserve by Tc-99m Sestamibi Imaging in Children With Kawasaki Disease (267 views)
Eur J Nucl Med (ISSN: 1619-7070, 1619-7089, 0340-6997), 2009 Sep; 36: N/D-N/D.
Impact Factor: 4.531
View Export to BibTeX Export to EndNote
Storto G, Pellegrino T, Vassallo S, De Marino M, De Falco T, Punzo G, Petretta A, Cuocolo A
* Assessment of the Arterial Input Function for the Estimation of Coronary Flow Reserve by SPECT Imaging: Comparison of Two Different Methods (321 views)
Eur J Nucl Med (ISSN: 1619-7070, 1619-7089, 0340-6997), 2008 Oct; 35: N/D-N/D.
Impact Factor: 4.532
View Export to BibTeX Export to EndNote
Petretta M, Costanzo P, Acampa W, Imbriaco M, Ferro A, Filardi PP, Cuocolo A
* Noninvasive assessment of coronary anatomy and myocardial perfusion: Going toward an integrated imaging approach (343 views)
J Cardiovasc Med (ISSN: 1558-2027, 1558-2035), 2008 Oct; 9(10): 977-986.
Impact Factor: 1.407
View Export to BibTeX Export to EndNote
Sciacca MFM, Pappalardo M, Milardi D, Grasso DM, La Rosa C
* Calcium-Activated Membrane Interaction Of The Islet Amyloid Polypeptide: Implications In The Pathogenesis Of Type Ii Diabetes Mellitus (962 views)
Arch Biochem Biophys, 2008 Sep 15; 65(1-2): 291-298.
Impact Factor: 3.043
View Export to BibTeX Export to EndNote
Storto G, Sorrentino AR, Pellegrino T, Liuzzi R, Petretta M, Cuocolo A
* Assessment of coronary flow reserve by sestamibi imaging in patients with typical chest pain and normal coronary arteries (vol 34, pg 1156, 2007) (284 views)
Eur J Nucl Med (ISSN: 1619-7070, 1619-7089, 0340-6997), 2008 Sep; 35(9): N/D-N/D.
Impact Factor: 4.532
View Export to BibTeX Export to EndNote
Petretta M, Soricelli A, Storto G, Cuocolo A
* Assessment of coronary flow reserve using single photon emission computed tomography with technetium 99m-labeled tracers (416 views)
J Nucl Cardiol (ISSN: 1532-6551, 1071-3581, 1532-6551electronic), 2008 May; 15(3): 456-465.
Impact Factor: 2.442
View Export to BibTeX Export to EndNote
Petretta M, Acampa W, Evangelista L, Daniele S, Ferro A, Cuocolo A
* Impact of inducible ischemia by stress SPECT in cardiac risk assessment in diabetic patients: Rationale and design of a prospective, multicenter trial (308 views)
J Nucl Cardiol (ISSN: 1071-3581, 1532-6551, 1532-6551electronic), 2008 Jan; 15(1): 100-104.
Impact Factor: 2.442
View Export to BibTeX Export to EndNote
Storto G, Sorrentino AR, Pellegrino T, Liuzzi R, Petretta M, Cuocolo A
* Assessment of coronary flow reserve by sestamibi imaging in patients with typical chest pain and normal coronary arteries (355 views)
Eur J Nucl Med (ISSN: 1619-7070, 1619-7089, 0340-6997), 2007 Sep; 34(8): 1156-1161.
Impact Factor: 4.101
View Export to BibTeX Export to EndNote
Storto G, Sorrentino AR, Pellegrino T, Liuzzi R, Peretta M, Cuocolo A
* Coronary Flow Reserve By Sistemibi Imaging In Patients With Typical Chest Pain And Normal Coronary Arteries (255 views)
European Journal Of Nuclear Medicine And Molecular Imaging, 2006; 0: N/D-N/D.
Impact Factor: 5.217
View Export to BibTeX Export to EndNote
Palmieri V, Storto G, Arezzi E, Pellegrino T, Mancini M, Di Minno G, Ferrara AL, Cuocolo A, Celentano A
* Relations of left ventricular mass and systolic function to endothelial function and coronary flow reserve in healthy, new discovered hypertensive subjects (311 views)
J Hum Hypertens (ISSN: 0950-9240), 2005 Dec; 19(12): 941-950.
Impact Factor: 2.405
View Export to BibTeX Export to EndNote
Pellegrino T, Storto G, Filardi PP, Sorrentino AR, Silvestro A, Petretta M, Brevetti G, Chiariello M, Salvatore M, Cuocolo A
* Relationship between brachial artery flow-mediated dilation and coronary flow reserve in patients with peripheral artery disease (330 views)
J Nucl Med (ISSN: 0161-5505, 1535-5667, 1535-5667electronic), 2005 Dec; 46(12): 1997-2002.
Impact Factor: 4.684
View Export to BibTeX Export to EndNote
Vicario MLE, Cirillo L, Storto G, Pellegrino T, Ragone N, Fontanella L, Petretta M, Bonaduce D, Cuocolo A
* Influence of risk factors on coronary flow reserve in patients with 1-vessel coronary artery disease (350 views)
J Nucl Med (ISSN: 0161-5505, 1535-5667, 1535-5667electronic), 2005 Sep; 46(9): 1438-1443.
Impact Factor: 4.684
View Export to BibTeX Export to EndNote
Storto G, Vicario MLE, Pellegrino T, Cirillo L, Ragone N, Fontanella L, Petretta M, Bonaduce D, Cuocolo A
* Influence of Risk Factors on Tc-99m Sestamibi Estimated Coronary Flow Reserve in Patients with One-vessel Coronary Artery Disease (227 views)
Eur J Nucl Med (ISSN: 1619-7070, 1619-7089, 0340-6997), 2005 Sep; 32: N/D-N/D.
Impact Factor: 3.883
View Export to BibTeX Export to EndNote
Perrone-Filardi P, Silvestro A, Pellegrino T, Brevetti G, Corrado L, Cafiero M, Chiariello M, Cuocolo A
* Relation between coronary flow reserve and flow mediated dilation index in patients with peripheral artery disease (237 views)
European Heart Journal (ISSN: 0195-668x), 2005 Sep; 26: N/D-N/D.
Impact Factor: 7.341
View Export to BibTeX Export to EndNote
Pellegrino T, Storto G, Sorrentino AR, Filardi PP, Silvestri A, Petretta M, Brevetti G, Cuocolo A
* Relation Between Tc-99m Sestamibi Estimated Coronary Flow Reserve and Flow Mediated Dilation Index in Patients with Peripheral Artery Disease (238 views)
Eur J Nucl Med (ISSN: 1619-7070, 1619-7089, 0340-6997), 2005 Sep; 32: N/D-N/D.
Impact Factor: 3.883
View Export to BibTeX Export to EndNote
Storto G, Cirillo P, Eufrasia Vicario ML, Pellegrino T, Sorrentino AR, Petretta M, Galasso G, De Sanctis V, Piscione F, Cuocolo A
* Estimation of coronary flow reserve by Tc-99m sestamibi imaging in patients with coronary artery disease: Comparison with the results of intracoronary Doppler technique (421 views)
J Nucl Cardiol (ISSN: 1071-3581, 1532-6551, 1532-6551electronic), 2004 Nov; 11(6): 682-688.
Impact Factor: 1.849
View Export to BibTeX Export to EndNote
Storto G, Pellegrino T, Cirillo P, Sorrentino A, Galasso G, Piscione F, Salvatore M, Cuocolo A
* Estimation of coronary flow reserve by Tc-99m sestamibi imaging in patients with coronary artery disease: Comparison with the results of intracoronary Doppler technique (265 views)
Eur J Nucl Med (ISSN: 1619-7070, 1619-7089, 0340-6997), 2004 Sep; 31: N/D-N/D.
Impact Factor: 3.935
View Export to BibTeX Export to EndNote
38 Records (26 excluding Abstracts).
Total impact factor: 161.684 (109.407 excluding Abstracts).
Total 5 year impact factor: 163.869 (104.884 excluding Abstracts).
Total impact factor: 161.684 (109.407 excluding Abstracts).
Total 5 year impact factor: 163.869 (104.884 excluding Abstracts).
322 views. Last view on Saturday 14 January 2023, 17:53:58
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