Synthesis, spectroscopic studies and biological activity of a novel nucleopeptide with Moloney murine leukemia virus reverse transcriptase inhibitory activity
Synthesis, spectroscopic studies and biological activity of a novel nucleopeptide with Moloney murine leukemia virus reverse transcriptase inhibitory activity(443 views) Roviello GN, Di Gaetano S, Capasso D, Cesarani A, Bucci EM, Pedone C
Keywords: Pna, Reverse Transcriptase, Virus, Alpha, Epsilon Lysine Peptide Nucleic Acid, Messenger Rna, Nucleotide, Oligomer, Rna Directed Dna Polymerase, Rna Directed Dna Polymerase Inhibitor, Unclassified Drug, Primer Dna, Antiviral Activity, Article, Biological Activity, Circular Dichroism, Competitive Inhibition, Concentration Response, Controlled Study, Drug Protein Binding, Drug Stability, Drug Structure, Electrospray Mass Spectrometry, Enzyme Assay, Enzyme Inhibition, Hela Cell, Human, In Vitro Study, Moloney Leukemia Oncovirus, Oligomerization, Priority Journal, Reverse Transcription, Reversed Phase High Performance Liquid Chromatography, Solid Phase Synthesis, Ultraviolet Spectroscopy, Agar Gel Electrophoresis, Chemistry, Enzymology, Nucleotide Sequence, Reverse Transcription Polymerase Chain Reaction, Ultraviolet Spectrophotometry, Eukaryota, Moloney Murine Leukemia Virus, Base Sequence, High Pressure Liquid, Dna Primers, Reverse Transcriptase Inhibitors, Reverse Transcriptase Polymerase Chain Reaction, Electrospray Ionization,
Affiliations: *** IBB - CNR ***
Istituto di Biostrutture e Bioimmagini, CNR, via Mezzocannone 16, 80134 Naples, Italy
Dipartimento Delle Scienze Biologiche, Università di Napoli Federico II, 80134 Naples, Italy
References: Boiziau, C., Thuong, N.T., Toulmé, J.J., Mechanisms of the inhibition of reverse transcription by antisense oligonucleotides (1992) Proc Natl Acad Sci USA, 89, pp. 768-77
Briones, C., Martin-Gago, J.A., Nucleic acids and their analogs as nanomaterials for biosensor development (2006) Curr Nanosci, 2, pp. 257-273
Chan, E.W., Lee, C.K., Dale, P.J., Antiviral properties of polyinosinic acids containing thio and methyl substitutions (1981) Journal of General Virology, 52 (2), pp. 291-299
Fukui, T., De Clercq, E., Inhibition of murine leukaemia virus reverse transcriptase by 2-halogenated polyadenylic acids (1982) Biochemical Journal, 203 (3), pp. 755-760
Gangamani, B.P., Kumar, V.A., Ganesh, K.N., Chiral analogues of peptide nucleic acids: Synthesis of 4-aminoprolyl nucleic acids and DNA complementation studies using UV/CD spectroscopy (1999) Tetrahedron, 55 (1), pp. 177-192. , DOI 10.1016/S0040-4020(98)01024-2, PII S0040402098010242
Georgiadis, M.M., Jessen, S.M., Ogata, C.M., Telesnitsky, A., Goff, S.P., Mechanistic implications from the structure of a catalytic fragment of Moloney murine leukemia virus reverse transcriptase (1995) Structure, 3, pp. 879-892. , Hendrickson WA
Haimaa, G., Lohse, A., Buchardt, O., Nielsen, P.E., Peptide nucleic acids (PNAs) containing thymine monomers derived from chiral amino acids: Hybridization and solubility properties of D-lysine PNA (1996) Angew Chem Int Ed Engl, 35, pp. 1939-1942
Helene, C., Le Doan, T., Oligonucleotides: Problems and frontiers of practical applications (1991) Trends Biotechnol, 9, pp. 339-340
Huang, H., Chopra, R., Verdine, G.L., Harrison, S.C., Structure of a covalently trapped catalytic complex of HIV-1 reverse transcriptase: Implications for drug resistance (1998) Science, 282 (5394), pp. 1669-1675
Kotewicz, M.L., Sampson, C.M., D'Alessio, J.M., Gerard, G.F., Isolation of cloned Moloney murine leukemia virus reverse transcriptase lacking ribonuclease H activity (1988) Nucleic Acids Res, 16, pp. 265-277
Krzyzanowska, D., Lisowski, M., Kochman, M., UV-difference and CD spectroscopy studies on juvenile hormone binding to its carrier protein (1998) Journal of Peptide Research, 51 (2), pp. 96-102
Kurreck, J., Antisense technologies: Improvement through novel chemical modifications (2003) European Journal of Biochemistry, 270 (8), pp. 1628-1644. , DOI 10.1046/j.1432-1033.2003.03555.x
Maga, G., Ubiali, D., Salvetti, R., Pregnolato, M., Spadari, S., Selective interaction of the human immunodeficiency virus type 1 reverse transcriptase nonnucleoside inhibitor efavirenz and its thio-substituted analog with different enzyme-substrate complexes (2000) Antimicrobial Agents and Chemotherapy, 44 (5), pp. 1186-1194. , DOI 10.1128/AAC.44.5.1186-1194.2000
Molling, K., Bolognesi, D.P., Bauer, H., Busen, W., Plassmann, H.W., Hausen, P., Association of viral reverse transcriptase with an enzyme degrading the RNA moiety of RNA-DNA hybrids (1971) Nat New Biol, 234, pp. 240-243
Motakis, D., Parniak, M.A., A tight-binding mode of inhibition is essential for anti-human immunodeficiency virus type 1 virucidal activity of nonnucleoside reverse transcriptase inhibitors (2002) Antimicrobial Agents and Chemotherapy, 46 (6), pp. 1851-1856. , DOI 10.1128/AAC.46.6.1851-1856.2002
Nielsen, P.E., Egholm, M., Berg, R.H., Buchardt, O., Sequence-selective recognition of DNA by strand displacement with a thymine-substituted polyamide (1991) Science, 254 (5037), pp. 1497-1500
Ray, A., Norden, B., Peptide nucleic acid (PNA): Its medical and biotechnical applications and promise for the future (2000) FASEB Journal, 14 (9), pp. 1041-1060
Rittinger, K., Divita, G., Goody, R.S., Human immunodeficiency virus reverse transcriptase substrate-induced conformational changes and the mechanism of inhibition by nonnucleoside inhibitors (1995) Proc Natl Acad Sci USA, 92, pp. 8046-8049
Rocchi, R., Borin, G., Marchiori, F., Moroder, L., Peggion, E., Scoffone, E., Crescenzi, V., Quadrifoglio, F., Interaction of S-protein with S-peptide and with synthetic S-peptide analogs. A spectroscopic and calorimetric investigation (1972) Biochemistry, 11, pp. 50-57
Roviello, G.N., Moccia, M., Sapio, R., Valente, M., Bucci, E.M., Castiglione, M., Pedone, C., Musumeci, D., Synthesis, characterization and hybridization studies of new nucleo-γ-peptides based on diaminobutyric acid (2006) Journal of Peptide Science, 12 (12), pp. 829-835. , DOI 10.1002/psc.819
Roviello, G.N., Musumeci, D., Moccia, M., Castiglione, M., Sapio, R., Valente, M., Bucci, E.M., Pedone, C., DabPNA: Design, synthesis, and DNA binding studies (2007) Nucleosides, Nucleotides and Nucleic Acids, 26 (10-12), pp. 1307-1310. , DOI 10.1080/15257770701530640, PII 788145344
Sforza, S., Haaima, G., Marchelli, R., Nielsen, P.E., Chiral peptide nucleic acids (PNAs): Helix handedness and DNA recognition (1999) Eur J Org Chem, 1, pp. 197-204
Sforza, S., Galaverna, G., Dossena, A., Corradini, R., Marchelli, R., Role of chirality and optical purity in nucleic acid recognition by PNA and PNA analogs (2002) Chirality, 14 (7), pp. 591-598. , DOI 10.1002/chir.10087
Uhlmann, E., Peyman, A., Breipohl, G., Will, D.W., PNA: Synthetic polyamide nucleic acids with unusual binding properties (1998) Angewandte Chemie - International Edition, 37 (20), pp. 2796-2823. , DOI 10.1002/(SICI)1521-3773(19981102)37:20<2796::AID-ANIE2796>
3.0. CO
Williams, K.J., Loeb, L.A., Fry, M., Synthesis of DNA by human immunodeficiency virus reverse transcriptase is preferentially blocked at template oligo(deoxyadenosine) tracts (1990) J Biol Chem, 265, pp. 18682-18689
Wu, L., Huang, M.-H., Zhao, J.-L., Yang, M.-S., Study of MMLV RT- binding with DNA using surface plasmon resonance biosensor (2005) Acta Biochimica et Biophysica Sinica, 37 (9), pp. 634-642. , DOI 10.1111/j.1745-7270.2005.00088.x
Yang, S.S., Cragg, G.M., Newman, D.J., Bader, J.P., Natural product-based anti-HIV drug discovery and development facilitated by the NCI Developmental Therapeutics Program (2001) Journal of Natural Products, 64 (2), pp. 265-277. , DOI 10.1021/np0003995
Synthesis, spectroscopic studies and biological activity of a novel nucleopeptide with Moloney murine leukemia virus reverse transcriptase inhibitory activity
Synthesis, spectroscopic studies and biological activity of a novel nucleopeptide with Moloney murine leukemia virus reverse transcriptase inhibitory activity
No results.
Synthesis, spectroscopic studies and biological activity of a novel nucleopeptide with Moloney murine leukemia virus reverse transcriptase inhibitory activity
Kim YH, Shin SW, Pellicano R, Fagoonee S, Choi IJ, Kim YI, Park B, Choi JM, Kim SG, Choi J, Park JY, Oh S, Yang HJ, Lim JH, Im JP, Kim JS, Jung HC, Ponzetto A, Figura N, Malfertheiner P, Choi IJ, Kook MC, Kim YI, Cho SJ, Lee JY, Kim CG, Park B, Nam BH, Bae SE, Choi KD, Choe J, Kim SO, Na HK, Choi JY, Ahn JY, Jung KW, Lee J, Kim DH, Chang HS, Song HJ, Lee GH, Jung HY, Seta T, Takahashi Y, Noguchi Y, Shikata S, Sakai T, Sakai K, Yamashita Y, Nakayama T, Leja M, Park JY, Murillo R, Liepniece-karele I, Isajevs S, Kikuste I, Rudzite D, Krike P, Parshutin S, Polaka I, Kirsners A, Santare D, Folkmanis V, Daugule I, Plummer M, Herrero R, Tsukamoto T, Nakagawa M, Kiriyama Y, Toyoda T, Cao X, Corral JE, Mera R, Dye CW, Morgan DR, Lee YC, Lin JT, Garcia Martin R, Matia Cubillo A, Lee SH, Park JM, Han YM, Ko WJ, Hahm KB, Leontiadis GI, Ford AC, Ichinose M, Sugano K, Jeong M, Park JM, Han YM, Park KY, Lee DH, Yoo JH, Cho JY, Hahm KB, Bang CS, Baik GH, Shin IS, Kim JB, Suk KT, Yoon JH, Kim YS, Kim DJ * Helicobacter pylori Eradication for Prevention of Metachronous Recurrence after Endoscopic Resection of Early Gastric Cancer(297 views) N Engl J Med (ISSN: 0028-4793, 0028-4793linking, 1533-4406electronic), 2015 Jun; 30642104201566393291: 749-756. Impact Factor:59.558 ViewExport to BibTeXExport to EndNote
Santulli G, Cipolletta E, Sorriento D, Del Giudice C, Anastasio A, Monaco S, Maione AS, Condorelli G, Puca A, Trimarco B, Illario M, Iaccarino G * CaMK4 gene deletion induces hypertension(349 views) J Am Heart Assoc Journal Of The American Heart Association (ISSN: 2047-9980), 2012; 1(4): N/D-N/D. Impact Factor:2.882 ViewExport to BibTeXExport to EndNote