In vivo labeling of B16 melanoma tumor xenograft with a thiol-reactive gadolinium based MRI contrast agent(690 views) Menchise V, Digilio G, Gianolio E, Cittadino E, Catanzaro V, Carrera C, Aime S
Institute for Biostructures and Bioimages (CNR), C/o Molecular Biotechnology Center (University of Turin), Via Nizza 52, I-10126 Torino, Italy
Department of Environmental and Life Sciences, Università Del Piemonte Orientale A. Avogadro, Viale T. Michel 11, I-15121 Alessandria, Italy
Department of Chemisty, IFM and Center for Molecular Imaging, University of Turin, Via Nizza 52, I-10126 Torino, Italy
References: Gatenby, R.A., Gillies, R.J., Why do cancers have high aerobic glycolysis? (2004) Nature Reviews Cancer, 4 (11), pp. 891-899. , DOI 10.1038/nrc147
Rofstad, E.K., Microenvironment-induced cancer metastasis (2000) International Journal of Radiation Biology, 76 (5), pp. 589-605
Raghunand, N., Jagadish, B., Trouard, T.P., Galons, J.-P., Gillies, R.J., Mash, E.A., Redox-sensitive contrast agents for MRI based on reversible binding of thiols to serum albumin (2006) Magnetic Resonance in Medicine, 55 (6), pp. 1272-1280. , DOI 10.1002/mrm.20904
Jonas, C.R., Ziegler, T.R., Gu, L.H., Jones, D.P., Extracellular thiol/disulfide redox state affects proliferation rate in a human colon carcinoma (Caco2) cell line (2002) Free Radical Biology and Medicine, 33 (11), pp. 1499-1506. , DOI 10.1016/S0891-5849(02)01081-X, PII S089158490201081X
Jonas, C.R., Gu, L.H., Nkabyo, Y.S., Mannery, Y.O., Avissar, N.E., Sax, H.C., Jones, D.P., Ziegler, T.R., Glutamine and KGF each regulate extracellular thiol/disulfide redox and enhance proliferation in Caco-2 cells (2003) Am. J. Physiol., 285, pp. 1421-R1429
Rehman, F., Shanmugasundaram, P., Schrey, M.P., Fenretinide stimulates redox-sensitive ceramide production in breast cancer cells: Potential role in drug-induced cytotoxicity (2004) British Journal of Cancer, 91 (10), pp. 1821-1828. , DOI 10.1038/sj.bjc.6602212
Prezioso, J.A., Shields, D., Wang, N., Rosenstein, M., Role of gamma-glutamyltranspeptidase-mediated glutathione transport on the radiosensitivity of B16 melanoma variant cell lines (1994) Int. J. Radiat. Oncol. Biol. Phys., 30, pp. 373-381
Paolicchi, A., Lorenzini, E., Perego, P., Supino, R., Zunino, F., Comporti, M., Pompella, A., Extra-cellular thiol metabolism in clones of human metastatic melanoma with different gamma-glutamyl transpeptidase expression: Implications for cell response to platinum-based drugs (2002) International Journal of Cancer, 97 (6), pp. 740-745. , DOI 10.1002/ijc.10110
Glunde, K., Gillies, R.J., Neeman, M., Bhujwalla, Z.M., (2010) Molecular Imaging: Principles and Practice, pp. 844-863. , Weissleder, R. Ross, B. D. Rehemtulla, A. Gambhir, S. S. Eds. PMPH-USA: Beijing
Glunde, K., Pathak, A.P., Bhujwalla, Z.M., Molecular-functional imaging of cancer: To image and imagine (2007) Trends in Molecular Medicine, 13 (7), pp. 287-297. , DOI 10.1016/j.molmed.2007.05.002, PII S147149140700086X
Penet, M.-F., Pathak, A.P., Raman, V., Ballesteros, P., Artemov, D., Bhujwalla, Z.M., Noninvasive Multiparametric Imaging of Metastasis-Permissive Microenvironments in a Human Prostate Cancer Xenograft (2009) Cancer Res., 69 (22), pp. 8822-8829
Neeman, M., Provenzale, J.M., Dewhirst, M.W., Magnetic resonance imaging applications in the evaluation of tumor angiogenesis (2001) Seminars in Radiation Oncology, 11 (1), pp. 70-82
Bhujwalla, Z.M., Artemov, D., Ballesteros, P., Cerdan, S., Gillies, R.J., Solaiyappan, M., Combined vascular and extracellular pH imaging of solid tumors (2002) NMR in Biomedicine, 15 (2), pp. 114-119. , DOI 10.1002/nbm.743
Garcia-Espinosa, M.A., Rodrigues, T.B., Sierra, A., Benito, M., Fonseca, C., Gray, H.L., Bartnik, B.L., Cerdan, S., Cerebral glucose metabolism and the glutamine cycle as detected by in vivo and in vitro 13C NMR spectroscopy (2004) Neurochemistry International, 45 (2-3), pp. 297-303. , DOI 10.1016/j.neuint.2003.08.014, PII S0197018603002845
Manzoor, A.A., Yuan, H., Palmer, G.M., Viglianti, B.L., Dewhirst, M.K., (2010) Molecular Imaging: Principles and Practice, pp. 756-780. , Weissleder, R. Ross, B. D. Rehemtulla, A. Gambhir, S. S. PMPH-USA: Beijing
Cook, J.A., Gius, D., Wink, D.A., Krishna, M.C., Russo, A., Mitchell, J.B., Oxidative stress, redox, and the tumor microenvironment (2004) Seminars in Radiation Oncology, 14 (3), pp. 259-266. , DOI 10.1016/j.semradonc.2004.04.001, PII S1053429604000529
Groves, A.M., Win, T., Ben Haim, S., Ell, P.J., Non-[18F]FDG PET in clinical oncology (2007) Lancet Oncol., 8, pp. 822-830
Rischin, D., Hicks, R.J., Fisher, R., Binns, D., Corry, J., Porceddu, S., Peters, L.J., Prognostic significance of [ 18F]-misonidazole positron emission tomography-detected tumor hypoxia in patients with advanced head and neck cancer randomly assigned to chemoradiation with or without tirapazamine: A substudy of Trans-Tasman Radiation Oncology Group study 98.02 (2006) Journal of Clinical Oncology, 24 (13), pp. 2098-2104. , DOI 10.1200/JCO.2005.05.2878
Eschmann, S.-M., Paulsen, F., Reimold, M., Dittmann, H., Welz, S., Reischl, G., MacHulla, H.-J., Bares, R., Prognostic impact of hypoxia imaging with 18F-misonidazole PET in non-small cell lung cancer and head and neck cancer before radiotherapy (2005) Journal of Nuclear Medicine, 46 (2), pp. 253-260
Hyodo, F., Soule, B.P., Matsumoto, K.-I., Matsumoto, S., Cook, J.A., Hyodo, E., Sowers, A.L., Mitchell, J.B., Assessment of tissue redox status using metabolic responsive contrast agents and magnetic resonance Imaging (2008) J. Pharm. Pharmacol., 60 (8), pp. 1049-1060
Aime, S., Botta, M., Gianolio, E., Terreno, E., A p(O 2)-responsive MRI contrast agent based on the redox switch of manganese(II/III) - Porphyrin complexes (2000) Angewandte Chemie - International Edition, 39 (4), pp. 747-750. , DOI 10.1002/(SICI)1521-3773(20000218)39:4<747::AID-ANIE747>
3.0. CO
Moriarty-Craige, S.E., Jones, D.P., Extracellular thiols and thiol/disulfide redox in metabolism (2004) Annual Review of Nutrition, 24, pp. 481-509. , DOI 10.1146/annurev.nutr.24.012003.132208
Schafer, F.Q., Buettner, G.R., Redox environment of the cell as viewed through the redox state of the glutathione disulfide/glutathione couple (2001) Free Radical Biology and Medicine, 30 (11), pp. 1191-1212. , DOI 10.1016/S0891-5849(01)00480-4, PII S0891584901004804
Ghezzi, P., Oxidoreduction of protein thiols in redox regulation (2005) Biochemical Society Transactions, 33 (6), pp. 1378-1381. , DOI 10.1042/BST20051378
Sahaf, B., Heydari, K., Herzenberg, L.A., Herzenberg, L.A., Lymphocyte surface thiol levels (2003) Proceedings of the National Academy of Sciences of the United States of America, 100 (7), pp. 4001-4005. , DOI 10.1073/pnas.2628032100
Digilio, G., Menchise, V., Gianolio, E., Catanzaro, V., Carrera, C., Napolitano, R., Fedeli, F., Aime, S., Exofacial protein thiols as a route for the internalization of Gd(III)-based complexes for MRI cell labelling (2010) J. Med. Chem., 53, pp. 4877-4890
Laragione, T., Gianazza, E., Tonelli, R., Bigini, P., Mennini, T., Casoni, F., Massignan, T., Ghezzi, P., Regulation of redox-sensitive exofacial protein thiols in CHO cells (2006) Biological Chemistry, 387 (10-11), pp. 1371-1376. , DOI 10.1515/BC.2006.172, PII BCHM38710111371
Jiang, X.-M., Fitzgerald, M., Grant, C.M., Hogg, P.J., Redox Control of Exofacial Protein Thiols/Disulfides by Protein Disulfide Isomerase (1999) J. Biol. Chem., 274, pp. 2416-2423
Laragione, T., Bonetto, V., Casoni, F., Massignan, T., Bianchi, G., Gianazza, E., Ghezzi, P., Redox regulation of surface protein thiols: Identification of integrin α-4 as a molecular target by using redox proteomics (2003) Proceedings of the National Academy of Sciences of the United States of America, 100 (25), pp. 14737-14741. , DOI 10.1073/pnas.2434516100
Digilio, G., Catanzaro, V., Fedeli, F., Gianolio, E., Menchise, V., Napolitano, R., Gringeri, C., Aime, S., Targeting exofacial protein thiols with GdIII complexes. An efficient procedure for MRI cell labelling (2009) Chem. Commun., pp. 893-895
Carrera, C., Digilio, G., Baroni, S., Burgio, D., Consol, S., Fedeli, F., Longo, D., Aime, S., Synthesis and characterization of a Gd(III) based contrast agent responsive to thiol containing compounds (2007) Dalton Transactions, (43), pp. 4980-4987. , DOI 10.1039/b705088g
Bradford, M.M., A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding (1976) Anal. Biochem., 72, pp. 248-254
Crich, S.G., Biancone, L., Cantaluppi, V., Duo, D., Esposito, G., Russo, S., Camussi, G., Aime, S., Improved Route for the Visualization of Stem Cells Labeled with a Gd-/Eu-Chelate as Dual (MRI and Fluorescence) Agent (2004) Magnetic Resonance in Medicine, 51 (5), pp. 938-944. , DOI 10.1002/mrm.20072
Crich, S.G., Cabella, C., Barge, A., Belfiore, S., Ghirelli, C., Lattuada, L., Lanzardo, S., Aime, S., In vitro and in vivo magnetic resonance detection of tumor cells by targeting glutamine transporters with Gd-based probes (2006) Journal of Medicinal Chemistry, 49 (16), pp. 4926-4936. , DOI 10.1021/jm0601093
Andersson, A., Lendgren, A., Hultberg, B., Effect of thiol oxidation and thiol export from erythrocytes on determination of redox status of homocysteine and other thiols in plasma from healthy subjects and patients with cerebral infarction (1995) Clin. Chem., 41, pp. 361-366
Peters Jr., T., (1996) All about Albumin
Biochemistry, Genetics and Medical Applications, , Academic Press: London
Raghunand, N., Guntle, G.P., Gokhale, V., Nichol, G.S., Mash, E.A., Jagadish, B., Design, synthesis, and evaluation of 1,4,7,10-tetraazacyclododecane-1,4, 7-triacetic acid derived, redox-sensitive contrast agents for magnetic resonance imaging (2010) J. Med. Chem., 53, pp. 6747-6757
In vivo labeling of B16 melanoma tumor xenograft with a thiol-reactive gadolinium based MRI contrast agent
Malvindi MA, Greco A, Conversano F, Figuerola A, Corti M, Bonora M, Lascialfari A, Doumari HA, Moscardini M, Cingolani R, Gigli G, Casciaro S, Pellegrino T, Ragusa A * MR Contrast Agents(292 views) Small Animal Imaging, 2011 Jul 8; 21(13): 2548-2555. Impact Factor:1.784 ViewExport to BibTeXExport to EndNote