Prognostic value of normal stress myocardial perfusion imaging in diabetic patients: a meta-analysis(603 views) Acampa W, Cantoni V, Green R, Maio F, Daniele S, Nappi C, Gaudieri V, Punzo G, Petretta M, Cuocolo A
Institute of Biostructure and Bioimaging, National Council of Research, Naples, Italy
SDN Foundation, Institute of Diagnostic and Nuclear Development, Naples, Italy
Department of Advanced Biomedical Sciences, University Federico II, Via Pansini 5, Naples, 80131, Italy
Department of Translational Medicine, University Federico II, Naples, Italy
References: Not available.
Prognostic value of normal stress myocardial perfusion imaging in diabetic patients: a meta-analysis
Background The prognostic value of normal stress myocardial perfusion single-photon emission computed tomography (MPS) in patients with diabetes has only been evaluated in single-center studies of relatively limited sample size. We performed a meta-analysis of published studies, including diabetic patients with known or suspected coronary artery disease (CAD), to assess the predictive value for adverse cardiac ischemic events of normal stress MPS. Methods and Results Studies published between January 1990 and December 2013 were identified by database search. We included studies using stress MPS to evaluate diabetic patients with known or suspected CAD and providing data on clinical outcomes of non-fatal myocardial infarction or cardiac death with a follow-up time 12 months. A total of 14 studies were finally included, recruiting 13, 493 patients. The negative predictive value (NPV) for non-fatal myocardial infarction and cardiac death of normal MPS was 94. 92% (95% confidence interval 93. 67-96. 05), during a weighted mean follow-up of 36. 24 months, resulting in estimated event rate after a negative test equal to 5. 08% (95% confidence interval 3. 95-6. 33). The corresponding annualized event rate after a negative test was 1. 60% (95% confidence interval 1. 21-2. 04). Conclusions Stress MPS has a high NPV for adverse cardiac events in diabetic patients with known or suspected CAD leading to define a "relatively low-risk" patients category. 2014 American Society of Nuclear Cardiology
Prognostic value of normal stress myocardial perfusion imaging in diabetic patients: a meta-analysis
Kim YH, Shin SW, Pellicano R, Fagoonee S, Choi IJ, Kim YI, Park B, Choi JM, Kim SG, Choi J, Park JY, Oh S, Yang HJ, Lim JH, Im JP, Kim JS, Jung HC, Ponzetto A, Figura N, Malfertheiner P, Choi IJ, Kook MC, Kim YI, Cho SJ, Lee JY, Kim CG, Park B, Nam BH, Bae SE, Choi KD, Choe J, Kim SO, Na HK, Choi JY, Ahn JY, Jung KW, Lee J, Kim DH, Chang HS, Song HJ, Lee GH, Jung HY, Seta T, Takahashi Y, Noguchi Y, Shikata S, Sakai T, Sakai K, Yamashita Y, Nakayama T, Leja M, Park JY, Murillo R, Liepniece-karele I, Isajevs S, Kikuste I, Rudzite D, Krike P, Parshutin S, Polaka I, Kirsners A, Santare D, Folkmanis V, Daugule I, Plummer M, Herrero R, Tsukamoto T, Nakagawa M, Kiriyama Y, Toyoda T, Cao X, Corral JE, Mera R, Dye CW, Morgan DR, Lee YC, Lin JT, Garcia Martin R, Matia Cubillo A, Lee SH, Park JM, Han YM, Ko WJ, Hahm KB, Leontiadis GI, Ford AC, Ichinose M, Sugano K, Jeong M, Park JM, Han YM, Park KY, Lee DH, Yoo JH, Cho JY, Hahm KB, Bang CS, Baik GH, Shin IS, Kim JB, Suk KT, Yoon JH, Kim YS, Kim DJ * Helicobacter pylori Eradication for Prevention of Metachronous Recurrence after Endoscopic Resection of Early Gastric Cancer(588 views) N Engl J Med (ISSN: 0028-4793, 0028-4793linking, 1533-4406electronic), 2015 Jun; 30642104201566393291: 749-756. Impact Factor:59.558 ViewExport to BibTeXExport to EndNote