Lipidated Peptides Via Post-Synthetic Thioalkylation Promoted By Molecular Sieves
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Lipidated Peptides Via Post-Synthetic Thioalkylation Promoted By Molecular Sieves (527 views)

Calce E, Leone M, Monfregola L, De Luca S

Amino Acids (ISSN: 0939-4451, 1438-2199, 1438-2199electronic), 2014; 46(8): 1899-1905.

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Paper type: Journal Article,

Impact factor: 3.293, 5-year impact factor: 3.269

Url: http://www.scopus.com/inward/record.url?eid=2-s2.0-84904755178&partnerID=40&md5=afc5736dff40098990e9075c761805c8

Keywords: Farnesylation, Lipidation, Molecular Sieves, Multi Derivatization, Peptide Thioalkylation, Lipidated Peptide, Peptide Derivative, Ras Protein, Unclassified Drug, Amino Acid Sequence, Analytical Equipment, Article, One Pot Synthesis, Priority Journal, Protein Processing, Protein Synthesis, Protein Thioalkylation,

Affiliations:
*** IBB - CNR ***

Institute of Biostructures and Bioimaging, National Research Council, 80134 Naples, Italy
Department of Chemistry and Biochemistry, University of Colorado, Boulder, CO 80309, United States


References:
Not available.
Lipidated Peptides Via Post-Synthetic Thioalkylation Promoted By Molecular Sieves

A thioalkylation procedure, which uses molecular sieves to promote the reaction, was exploited to provide peptides with useful functional groups (lipidic moieties), naturally occurring on proteins as post-translational modifications. The procedure was further implemented to synthesize tailor-made lipidated peptides, interesting tools to investigate biological processes involving their Ras parent proteins. Moreover, the one-pot preparation of multi-alkylated peptides confirms the versatility and flexibility of the employed methodology. 2014 Springer-Verlag
Lipidated Peptides Via Post-Synthetic Thioalkylation Promoted By Molecular Sieves

▼    Chemical modification of natural molecules, such as peptides and polysaccharides, to be employed as therapeutic agents as well as sensor diagnostic tools
Lipidated Peptides Via Post-Synthetic Thioalkylation Promoted By Molecular Sieves

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Verdoliva V, Digilio G, Saviano M, De Luca S
* Microwave Heating Promotes the S-Alkylation of Aziridine Catalyzed by Molecular Sieves: A Post-Synthetic Approach to Lanthionine-Containing Peptides (32 views)
Molecules (ISSN: 1420-3049linking, 1420-3049electronic), 2021 Oct 11; 26(20): 1-9.
Impact Factor: 4.411
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Verdoliva V, Digilio G, Saviano M, De Luca S
* Thio-conjugation of substituted benzofurazans to peptides: molecular sieves catalyze nucleophilic attack on unsaturated fused rings (14 views)
Catalysis Science & Technology, 2020; 11: 1067-1076.
Impact Factor: 6.119
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De Luca S, Digilio G, Verdoliva V, Tovillas P, Jimenez-oses G, Peregrina JM
* Lanthionine Peptides by S-Alkylation with Substituted Cyclic Sulfamidates promoted by Activated Molecular Sieves: Effects of the Sulfamidate Structure on the Yield (243 views)
J Org Chem (ISSN: 0022-3263linking), 2019 Nov 15; 84(22): 14957-14964.
Impact Factor: 4.745
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De Luca S, Digilio G, Verdoliva V, Saviano M, Menchise V, Tovillas P, Jimenez-oses G, Peregrina JM
* A Late-Stage Synthetic Approach to Lanthionine-Containing Peptides via S-Alkylation on Cyclic Sulfamidates Promoted by Molecular Sieves (317 views)
Org Lett (ISSN: 1523-7052electronic, 1523-7052linking, 1523-7060), 2018 Nov 14; N/D: N/D-N/D.
Impact Factor: 6.492
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Calce E, De Luca S
* Microwave heating in peptide side chain modification via cysteine alkylation (351 views)
Amino Acids (ISSN: 0939-4451, 1438-2199, 1438-2199electronic), 2016 Jun 28; 48: 2267-2271.
Impact Factor: 3.173
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Calce E, Leone M, Mercurio FA, Monfregola L, De Luca S
* Solid-Phase S-Alkylation Promoted by Molecular Sieves (275 views)
Org Lett (ISSN: 1523-7060, 1523-7052, 1523-7052electronic), 2015 Nov 20; 17(22): 5646-5649.
Impact Factor: 6.732
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Monfregola L, De Luca S
* Synthetic strategy for side chain mono-N-alkylation of Fmoc-amino acids promoted by molecular sieves (560 views)
Amino Acids (ISSN: 0939-4451, 1438-2199, 1438-2199electronic), 2011 Oct; 41(4): 981-990.
Impact Factor: 3.248
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7 Records (7 excluding Abstracts).
Total impact factor: 34.92 (34.92 excluding Abstracts).
Total 5 year impact factor: 25.597 (25.597 excluding Abstracts).

Last modified by Stefania De Luca on Sunday 12 July 2020, 13:14:52
527 views. Last view on Monday 06 November 2023, 11:26:01