Changes In Magnetic Resonance Imaging Disease Measures Over 3 Years In Mildly Disabled Patients With Relapsing-Remitting Multiple Sclerosis Receiving Interferon Beta-1a In The Cognitive Impairment In Multiple Sclerosis (cogimus) Study (361 views) (PDF public 224 views)
Bmc Neurol (ISSN: 1471-2377, 1471-2377linking), 2011 Oct 14; 11: 125-125.
Export to BibTeX Export to EndNote
Paper type: Abstract, Conference, Journal Article,
Impact factor: 2.167, 5-year impact factor: 2.63
Url: http://www.scopus.com/inward/record.url?eid=2-s2.0-80053964525&partnerID=40&md5=294f6fe80a54c354c1aa65c0008dba77
Keywords: Beta1a Interferon, Beta Interferon, Immunologic Factor, Adult, Article, Brain Damage, Cognitive Defect, Drug Dose Comparison, Human, Major Clinical Study, Multiple Sclerosis, Neuropsychology, Nuclear Magnetic Resonance Imaging, Observational Study, Outcome Assessment, Quality Of Life, Treatment Outcome, Clinical Trial, Dose Response, Drug Effect, Female, Methodology, Multicenter Study, Neuroimaging, Neuropsychological Test, Pathology, Psychological Aspect, Statistics, Cognition Disorders, Dose-Response Relationship, Interferon-Beta, Relapsing-Remitting,
Affiliations:
*** IBB - CNR ***
National Neurological Institute, C Mondino Foundation, IRCCS, Via Ferrata, I-27100, Pavia, Italy
European Biomedical Foundation Onlus, via Nizza 53, 00198, Rome, Italy
Department of Neurology, University of Florence, Viale Morgagni 85, 50134 Florence, Italy
IRCCS Foundazione Santa Lucia, Via Ardeatina 306, 00179 Rome, Italy
Biostructure and Bioimaging Institute, National Research Council, Via Pansini 5, 80131 Naples, Italy
Opera S. r. l., Via Sampierdarena 33, 16149 Genova, Italy
Opera S.r.l., Via Sampierdarena 33, 16149 Genova, Italy
References:
McDonald, W. I., Compston, A., Edan, G., Goodkin, D., Hartung, H. P., Lublin, F. D., McFarland, H. F., Wolinsky, J. S., Recommended diagnostic criteria for multiple sclerosis: guidelines from the International Panel on the Diagnosis of Multiple Sclerosis (2001) Ann Neurol, 50, pp. 121-127. , 10. 1002/ana. 1032, 1145630
Interferon beta-1b is effective in relapsing-remitting multiple sclerosis. I Clinical results of a multicenter, randomized, double-blind, placebo-controlled trial (1993) Neurology, 43, pp. 655-661. , IFNB Multiple Sclerosis Study Group
Johnson, K. P., Brooks, B. R., Cohen, J. A., Ford, C. C., Goldstein, J., Lisak, R. P., Myers, L. W., Schiffer, R. B., Copolymer 1 reduces relapse rate and improves disability in relapsing-remitting multiple sclerosis: results of a phase III multicenter, double-blind placebo-controlled trial (1995) Neurology, 45, pp. 1268-1276
Li, D. K., Paty, D. W., Magnetic resonance imaging results of the PRISMS trial: a randomized, double-blind, placebo-controlled study of interferon-beta1a in relapsing-remitting multiple sclerosis (1999) Ann Neurol, 46, pp. 197-206. , 10. 1002/1531-8249 (199908) 46: 2<197:: AID-ANA9> 3. 0. CO
2-P, 10443885, UBC MS/MRI Analysis Research Group, PRISMS Study Group
Simon, J. H., Jacobs, L. D., Campion, M., Wende, K., Simonian, N., Cookfair, D. L., Rudick, R. A., Whitham, R. H., Magnetic resonance studies of intramuscular interferon beta-1a for relapsing multiple sclerosis (1998) Ann Neurol, 43, pp. 79-87. , 10. 1002/ana. 410430114, 9450771
De Stefano, N., Curtin, F., Stubinski, B., Blevins, G., Drulovic, J., Issard, D., Shotekov, P., Gasperini, C., Rapid benefits of a new formulation of subcutaneous interferon beta-1a in relapsing-remitting multiple sclerosis (2010) Mult Scler, 16, pp. 888-892. , 10. 1177/1352458510362442, 20200197, IMPROVE Study Investigators
Randomised double-blind placebo-controlled study of interferon beta-1a in relapsing/remitting multiple sclerosis (1998) Lancet, 352, pp. 1498-1504. , 10. 1016/S0140-6736 (98) 03334-0, 9820297, PRISMS Study Group
Kappos, L., Traboulsee, A., Constantinescu, C., Er linna, J. P., Forrestal, F., Jongen, P., Pollard, J., Li, D., Long-term subcutaneous interferon beta-1a therapy in patients with relapsing-remitting MS (2006) Neurology, 67, pp. 944-953. , 10. 1212/01. wnl. 0000237994. 95410. ce, 17000959
Barkhof, F., The clinico-radiological paradox in multiple sclerosis revisited (2002) Curr Opin Neurol, 15, pp. 239-245. , 10. 1097/00019052-200206000-00003, 12045719
Zivadinov, R., Leist, T. P., Clinical-magnetic resonance imaging correlations in multiple sclerosis (2005) J Neuroimaging, 15 (4 SUPPL.), pp. 10S-21S
Amato, M. P., Zipoli, V., Portaccio, E., Multiple sclerosis-related cognitive changes: a review of cross-sectional and longitudinal studies (2006) J Neurol Sci, 245, pp. 41-46. , 10. 1016/j. jns. 2005. 08. 019, 16643953
Glanz, B. I., Healy, B. C., Rintell, D. J., Jaffin, S. K., Bakshi, R., Weiner, H. L., The association between cognitive impairment and quality of life in patients with early multiple sclerosis (2010) J Neurol Sci, 290, pp. 75-79. , 10. 1016/j. jns. 2009. 11. 004, 19944429
Rao, S. M., Leo, G. J., Ellington, L., Nauertz, T., Bernardin, L., Unverzagt, F., Cognitive dysfunction in multiple sclerosis. II. Impact on employment and social functioning (1991) Neurology, 41, pp. 692-696
Lazeron, R. H., de Sonneville, L. M., Scheltens, P., Polman, C. H., Barkhof, F., Cognitive slowing in multiple sclerosis is strongly associated with brain volume reduction (2006) Mult Scler, 12, pp. 760-768. , 10. 1177/1352458506070924, 17263004
Rovaris, M., Filippi, M., MRI correlates of cognitive dysfunction in multiple sclerosis patients (2000) J Neurovirol, 6 (SUPPL. 2), pp. S172-S175
Patti, F., Amato, M., Trojano, M., Bastianello, S., Tola, M. R., Goretti, B., Caniatti, L., Luccichenti, G., Cognitive impairment and its relation with disease measures in mildly disabled patients with relapsing-remitting multiple sclerosis: baseline results from the Cognitive Impairment in Multiple Sclerosis (COGIMUS) study (2009) Mult Scler, 15, pp. 779-788. , 10. 1177/1352458509105544, 19542262, COGIMUS Study Group
Amato, M. P., Portaccio, E., Goretti, B., Zipoli, V., Ricchiuti, L., De Caro, M. F., Patti, F., Trojano, M., The Rao's Brief Repeatable Battery and Stroop Test: normative values with age, education and gender corrections in an Italian population (2006) Mult Scler, 12, pp. 787-793. , 10. 1177/1352458506070933, 17263008
Colombo, L., Sartori, G., Brivio, C., La stima del quoziente intellettivo tramite l'Applicazione del TIB (Test di Intelligenza Breve) (2002) G Ital Psicol, 3, pp. 613-637
Fisk, J. D., Ritvo, P. G., Ross, L., Haase, D. A., Marrie, T. J., Schlech, W. F., Measuring the functional impact of fatigue: initial validation of the fatigue impact scale (1994) Clin Infect Dis, 18 (SUPPL. 1), pp. S79-S83
Hamilton, M., A rating scale for depression (1960) J Neurol Neurosurg Psychiatry, 23, pp. 56-62. , 10. 1136/jnnp. 23. 1. 56, 495331, 14399272
Mellerup, E., Fog, T., Raun, N., Colville, P., De Rham, B., Hannah, B., Kurtzke, J., The socio-economic scale (1981) Acta Neurol Scand, 64, pp. 130-138
Rudick, R. A., Miller, D., Hass, S., Hutchinson, M., Calabresi, P. A., Confavreux, C., Galetta, S. L., Panzara, M. A., Health-related quality of life in multiple sclerosis: effects of natalizumab (2007) Ann Neurol, 62, pp. 335-346. , 10. 1002/ana. 21163, 17696126, AFFIRM and SENTINEL Investigators
Summers, M., Swanton, J., Fernando, K., Dalton, C., Miller, D. H., Cipolotti, L., Ron, M. A., Cognitive impairment in multiple sclerosis can be predicted by imaging early in the disease (2008) J Neurol Neurosurg Psychiatry, 79, pp. 955-958. , 10. 1136/jnnp. 2007. 138685, 18339729
Deloire, M. S., Salort, E., Bonnet, M., Arimone, Y., Boudineau, M., Amieva, H., Barroso, B., Brochet, B., Cognitive impairment as marker of diffuse brain abnormalities in early relapsing remitting multiple sclerosis (2005) J Neurol Neurosurg Psychiatry, 76, pp. 519-526. , 10. 1136/jnnp. 2004. 045872, 1739602, 15774439
Patti, F., Failla, G., Ciancio, M. R., L'Episcopo, M. R., Reggio, A., Neuropsychological, neuroradiological and clinical findings in multiple sclerosis. A 3 year follow-up study (1998) Eur J Neurol, 5, pp. 283-286. , 10. 1046/j. 1468-1331. 1998. 530283. x, 10210843
Rudick, R. A., Lee, J. C., Simon, J., Fisher, E., Significance of T2 lesions in multiple sclerosis: a 13-year longitudinal study (2006) Ann Neurol, 60, pp. 236-242. , 10. 1002/ana. 20883, 16786526
Blinkenberg, M., Rune, K., Jensen, C. V., Ravnborg, M., Kyllingsbaek, S., Holm, S., Paulson, O. B., S rensen, P. S., Cortical cerebral metabolism correlates with MRI lesion load and cognitive dysfunction in MS (2000) Neurology, 54, pp. 558-564
Mowry, E. M., Beheshtian, A., Waubant, E., Goodin, D. S., Cree, B. A., Qualley, P., Lincoln, R., Pelletier, D., Quality of life in multiple sclerosis is associated with lesion burden and brain volume measures (2009) Neurology, 72, pp. 1760-1765. , 10. 1212/WNL. 0b013e3181a609f8, 2683738, 19451531
Calabrese, M., Filippi, M., Gallo, P., Cortical lesions in multiple sclerosis (2010) Nat Rev Neurol, 6, pp. 438-444. , 10. 1038/nrneurol. 2010. 93, 20625376
Calabrese, M., Rinaldi, F., Grossi, P., Gallo, P., Cortical pathology and cognitive impairment in multiple sclerosis (2011) Expert Rev Neurother, 11, pp. 425-432. , 10. 1586/ern. 10. 155, 21375447
McDonald, W.I., Compston, A., Edan, G., Goodkin, D., Hartung, H.P., Lublin, F.D., McFarland, H.F., Wolinsky, J.S., Recommended diagnostic criteria for multiple sclerosis: guidelines from the International Panel on the Diagnosis of Multiple Sclerosis (2001) Ann Neurol, 50, pp. 121-127. , 10.1002/ana.1032, 1145630
Johnson, K.P., Brooks, B.R., Cohen, J.A., Ford, C.C., Goldstein, J., Lisak, R.P., Myers, L.W., Schiffer, R.B., Copolymer 1 reduces relapse rate and improves disability in relapsing-remitting multiple sclerosis: results of a phase III multicenter, double-blind placebo-controlled trial (1995) Neurology, 45, pp. 1268-1276
Li, D.K., Paty, D.W., Magnetic resonance imaging results of the PRISMS trial: a randomized, double-blind, placebo-controlled study of interferon-beta1a in relapsing-remitting multiple sclerosis (1999) Ann Neurol, 46, pp. 197-206. , 10.1002/1531-8249(199908)46:2<197::AID-ANA9> 3.0.CO
Simon, J.H., Jacobs, L.D., Campion, M., Wende, K., Simonian, N., Cookfair, D.L., Rudick, R.A., Whitham, R.H., Magnetic resonance studies of intramuscular interferon beta-1a for relapsing multiple sclerosis (1998) Ann Neurol, 43, pp. 79-87. , 10.1002/ana.410430114, 9450771
Amato, M.P., Zipoli, V., Portaccio, E., Multiple sclerosis-related cognitive changes: a review of cross-sectional and longitudinal studies (2006) J Neurol Sci, 245, pp. 41-46. , 10.1016/j.jns.2005.08.019, 16643953
Glanz, B.I., Healy, B.C., Rintell, D.J., Jaffin, S.K., Bakshi, R., Weiner, H.L., The association between cognitive impairment and quality of life in patients with early multiple sclerosis (2010) J Neurol Sci, 290, pp. 75-79. , 10.1016/j.jns.2009.11.004, 19944429
Rao, S.M., Leo, G.J., Ellington, L., Nauertz, T., Bernardin, L., Unverzagt, F., Cognitive dysfunction in multiple sclerosis. II. Impact on employment and social functioning (1991) Neurology, 41, pp. 692-696
Lazeron, R.H., de Sonneville, L.M., Scheltens, P., Polman, C.H., Barkhof, F., Cognitive slowing in multiple sclerosis is strongly associated with brain volume reduction (2006) Mult Scler, 12, pp. 760-768. , 10.1177/1352458506070924, 17263004
Amato, M.P., Portaccio, E., Goretti, B., Zipoli, V., Ricchiuti, L., De Caro, M.F., Patti, F., Trojano, M., The Rao's Brief Repeatable Battery and Stroop Test: normative values with age, education and gender corrections in an Italian population (2006) Mult Scler, 12, pp. 787-793. , 10.1177/1352458506070933, 17263008
Fisk, J.D., Ritvo, P.G., Ross, L., Haase, D.A., Marrie, T.J., Schlech, W.F., Measuring the functional impact of fatigue: initial validation of the fatigue impact scale (1994) Clin Infect Dis, 18 (SUPPL. 1), pp. S79-S83
Rudick, R.A., Miller, D., Hass, S., Hutchinson, M., Calabresi, P.A., Confavreux, C., Galetta, S.L., Panzara, M.A., Health-related quality of life in multiple sclerosis: effects of natalizumab (2007) Ann Neurol, 62, pp. 335-346. , 10.1002/ana.21163, 17696126, AFFIRM and SENTINEL Investigators
Deloire, M.S., Salort, E., Bonnet, M., Arimone, Y., Boudineau, M., Amieva, H., Barroso, B., Brochet, B., Cognitive impairment as marker of diffuse brain abnormalities in early relapsing remitting multiple sclerosis (2005) J Neurol Neurosurg Psychiatry, 76, pp. 519-526. , 10.1136/jnnp.2004.045872, 1739602, 15774439
Rudick, R.A., Lee, J.C., Simon, J., Fisher, E., Significance of T2 lesions in multiple sclerosis: a 13-year longitudinal study (2006) Ann Neurol, 60, pp. 236-242. , 10.1002/ana.20883, 16786526
Mowry, E.M., Beheshtian, A., Waubant, E., Goodin, D.S., Cree, B.A., Qualley, P., Lincoln, R., Pelletier, D., Quality of life in multiple sclerosis is associated with lesion burden and brain volume measures (2009) Neurology, 72, pp. 1760-1765. , 10.1212/WNL.0b013e3181a609f8, 2683738, 19451531
Bmc Neurol (ISSN: 1471-2377, 1471-2377linking), 2011 Oct 14; 11: 125-125.
Export to BibTeX Export to EndNote
Paper type: Abstract, Conference, Journal Article,
Impact factor: 2.167, 5-year impact factor: 2.63
Url: http://www.scopus.com/inward/record.url?eid=2-s2.0-80053964525&partnerID=40&md5=294f6fe80a54c354c1aa65c0008dba77
Keywords: Beta1a Interferon, Beta Interferon, Immunologic Factor, Adult, Article, Brain Damage, Cognitive Defect, Drug Dose Comparison, Human, Major Clinical Study, Multiple Sclerosis, Neuropsychology, Nuclear Magnetic Resonance Imaging, Observational Study, Outcome Assessment, Quality Of Life, Treatment Outcome, Clinical Trial, Dose Response, Drug Effect, Female, Methodology, Multicenter Study, Neuroimaging, Neuropsychological Test, Pathology, Psychological Aspect, Statistics, Cognition Disorders, Dose-Response Relationship, Interferon-Beta, Relapsing-Remitting,
Affiliations:
*** IBB - CNR ***
National Neurological Institute, C Mondino Foundation, IRCCS, Via Ferrata, I-27100, Pavia, Italy
European Biomedical Foundation Onlus, via Nizza 53, 00198, Rome, Italy
Department of Neurology, University of Florence, Viale Morgagni 85, 50134 Florence, Italy
IRCCS Foundazione Santa Lucia, Via Ardeatina 306, 00179 Rome, Italy
Biostructure and Bioimaging Institute, National Research Council, Via Pansini 5, 80131 Naples, Italy
Opera S. r. l., Via Sampierdarena 33, 16149 Genova, Italy
Opera S.r.l., Via Sampierdarena 33, 16149 Genova, Italy
References:
McDonald, W. I., Compston, A., Edan, G., Goodkin, D., Hartung, H. P., Lublin, F. D., McFarland, H. F., Wolinsky, J. S., Recommended diagnostic criteria for multiple sclerosis: guidelines from the International Panel on the Diagnosis of Multiple Sclerosis (2001) Ann Neurol, 50, pp. 121-127. , 10. 1002/ana. 1032, 1145630
Interferon beta-1b is effective in relapsing-remitting multiple sclerosis. I Clinical results of a multicenter, randomized, double-blind, placebo-controlled trial (1993) Neurology, 43, pp. 655-661. , IFNB Multiple Sclerosis Study Group
Johnson, K. P., Brooks, B. R., Cohen, J. A., Ford, C. C., Goldstein, J., Lisak, R. P., Myers, L. W., Schiffer, R. B., Copolymer 1 reduces relapse rate and improves disability in relapsing-remitting multiple sclerosis: results of a phase III multicenter, double-blind placebo-controlled trial (1995) Neurology, 45, pp. 1268-1276
Li, D. K., Paty, D. W., Magnetic resonance imaging results of the PRISMS trial: a randomized, double-blind, placebo-controlled study of interferon-beta1a in relapsing-remitting multiple sclerosis (1999) Ann Neurol, 46, pp. 197-206. , 10. 1002/1531-8249 (199908) 46: 2<197:: AID-ANA9> 3. 0. CO
2-P, 10443885, UBC MS/MRI Analysis Research Group, PRISMS Study Group
Simon, J. H., Jacobs, L. D., Campion, M., Wende, K., Simonian, N., Cookfair, D. L., Rudick, R. A., Whitham, R. H., Magnetic resonance studies of intramuscular interferon beta-1a for relapsing multiple sclerosis (1998) Ann Neurol, 43, pp. 79-87. , 10. 1002/ana. 410430114, 9450771
De Stefano, N., Curtin, F., Stubinski, B., Blevins, G., Drulovic, J., Issard, D., Shotekov, P., Gasperini, C., Rapid benefits of a new formulation of subcutaneous interferon beta-1a in relapsing-remitting multiple sclerosis (2010) Mult Scler, 16, pp. 888-892. , 10. 1177/1352458510362442, 20200197, IMPROVE Study Investigators
Randomised double-blind placebo-controlled study of interferon beta-1a in relapsing/remitting multiple sclerosis (1998) Lancet, 352, pp. 1498-1504. , 10. 1016/S0140-6736 (98) 03334-0, 9820297, PRISMS Study Group
Kappos, L., Traboulsee, A., Constantinescu, C., Er linna, J. P., Forrestal, F., Jongen, P., Pollard, J., Li, D., Long-term subcutaneous interferon beta-1a therapy in patients with relapsing-remitting MS (2006) Neurology, 67, pp. 944-953. , 10. 1212/01. wnl. 0000237994. 95410. ce, 17000959
Barkhof, F., The clinico-radiological paradox in multiple sclerosis revisited (2002) Curr Opin Neurol, 15, pp. 239-245. , 10. 1097/00019052-200206000-00003, 12045719
Zivadinov, R., Leist, T. P., Clinical-magnetic resonance imaging correlations in multiple sclerosis (2005) J Neuroimaging, 15 (4 SUPPL.), pp. 10S-21S
Amato, M. P., Zipoli, V., Portaccio, E., Multiple sclerosis-related cognitive changes: a review of cross-sectional and longitudinal studies (2006) J Neurol Sci, 245, pp. 41-46. , 10. 1016/j. jns. 2005. 08. 019, 16643953
Glanz, B. I., Healy, B. C., Rintell, D. J., Jaffin, S. K., Bakshi, R., Weiner, H. L., The association between cognitive impairment and quality of life in patients with early multiple sclerosis (2010) J Neurol Sci, 290, pp. 75-79. , 10. 1016/j. jns. 2009. 11. 004, 19944429
Rao, S. M., Leo, G. J., Ellington, L., Nauertz, T., Bernardin, L., Unverzagt, F., Cognitive dysfunction in multiple sclerosis. II. Impact on employment and social functioning (1991) Neurology, 41, pp. 692-696
Lazeron, R. H., de Sonneville, L. M., Scheltens, P., Polman, C. H., Barkhof, F., Cognitive slowing in multiple sclerosis is strongly associated with brain volume reduction (2006) Mult Scler, 12, pp. 760-768. , 10. 1177/1352458506070924, 17263004
Rovaris, M., Filippi, M., MRI correlates of cognitive dysfunction in multiple sclerosis patients (2000) J Neurovirol, 6 (SUPPL. 2), pp. S172-S175
Patti, F., Amato, M., Trojano, M., Bastianello, S., Tola, M. R., Goretti, B., Caniatti, L., Luccichenti, G., Cognitive impairment and its relation with disease measures in mildly disabled patients with relapsing-remitting multiple sclerosis: baseline results from the Cognitive Impairment in Multiple Sclerosis (COGIMUS) study (2009) Mult Scler, 15, pp. 779-788. , 10. 1177/1352458509105544, 19542262, COGIMUS Study Group
Amato, M. P., Portaccio, E., Goretti, B., Zipoli, V., Ricchiuti, L., De Caro, M. F., Patti, F., Trojano, M., The Rao's Brief Repeatable Battery and Stroop Test: normative values with age, education and gender corrections in an Italian population (2006) Mult Scler, 12, pp. 787-793. , 10. 1177/1352458506070933, 17263008
Colombo, L., Sartori, G., Brivio, C., La stima del quoziente intellettivo tramite l'Applicazione del TIB (Test di Intelligenza Breve) (2002) G Ital Psicol, 3, pp. 613-637
Fisk, J. D., Ritvo, P. G., Ross, L., Haase, D. A., Marrie, T. J., Schlech, W. F., Measuring the functional impact of fatigue: initial validation of the fatigue impact scale (1994) Clin Infect Dis, 18 (SUPPL. 1), pp. S79-S83
Hamilton, M., A rating scale for depression (1960) J Neurol Neurosurg Psychiatry, 23, pp. 56-62. , 10. 1136/jnnp. 23. 1. 56, 495331, 14399272
Mellerup, E., Fog, T., Raun, N., Colville, P., De Rham, B., Hannah, B., Kurtzke, J., The socio-economic scale (1981) Acta Neurol Scand, 64, pp. 130-138
Rudick, R. A., Miller, D., Hass, S., Hutchinson, M., Calabresi, P. A., Confavreux, C., Galetta, S. L., Panzara, M. A., Health-related quality of life in multiple sclerosis: effects of natalizumab (2007) Ann Neurol, 62, pp. 335-346. , 10. 1002/ana. 21163, 17696126, AFFIRM and SENTINEL Investigators
Summers, M., Swanton, J., Fernando, K., Dalton, C., Miller, D. H., Cipolotti, L., Ron, M. A., Cognitive impairment in multiple sclerosis can be predicted by imaging early in the disease (2008) J Neurol Neurosurg Psychiatry, 79, pp. 955-958. , 10. 1136/jnnp. 2007. 138685, 18339729
Deloire, M. S., Salort, E., Bonnet, M., Arimone, Y., Boudineau, M., Amieva, H., Barroso, B., Brochet, B., Cognitive impairment as marker of diffuse brain abnormalities in early relapsing remitting multiple sclerosis (2005) J Neurol Neurosurg Psychiatry, 76, pp. 519-526. , 10. 1136/jnnp. 2004. 045872, 1739602, 15774439
Patti, F., Failla, G., Ciancio, M. R., L'Episcopo, M. R., Reggio, A., Neuropsychological, neuroradiological and clinical findings in multiple sclerosis. A 3 year follow-up study (1998) Eur J Neurol, 5, pp. 283-286. , 10. 1046/j. 1468-1331. 1998. 530283. x, 10210843
Rudick, R. A., Lee, J. C., Simon, J., Fisher, E., Significance of T2 lesions in multiple sclerosis: a 13-year longitudinal study (2006) Ann Neurol, 60, pp. 236-242. , 10. 1002/ana. 20883, 16786526
Blinkenberg, M., Rune, K., Jensen, C. V., Ravnborg, M., Kyllingsbaek, S., Holm, S., Paulson, O. B., S rensen, P. S., Cortical cerebral metabolism correlates with MRI lesion load and cognitive dysfunction in MS (2000) Neurology, 54, pp. 558-564
Mowry, E. M., Beheshtian, A., Waubant, E., Goodin, D. S., Cree, B. A., Qualley, P., Lincoln, R., Pelletier, D., Quality of life in multiple sclerosis is associated with lesion burden and brain volume measures (2009) Neurology, 72, pp. 1760-1765. , 10. 1212/WNL. 0b013e3181a609f8, 2683738, 19451531
Calabrese, M., Filippi, M., Gallo, P., Cortical lesions in multiple sclerosis (2010) Nat Rev Neurol, 6, pp. 438-444. , 10. 1038/nrneurol. 2010. 93, 20625376
Calabrese, M., Rinaldi, F., Grossi, P., Gallo, P., Cortical pathology and cognitive impairment in multiple sclerosis (2011) Expert Rev Neurother, 11, pp. 425-432. , 10. 1586/ern. 10. 155, 21375447
McDonald, W.I., Compston, A., Edan, G., Goodkin, D., Hartung, H.P., Lublin, F.D., McFarland, H.F., Wolinsky, J.S., Recommended diagnostic criteria for multiple sclerosis: guidelines from the International Panel on the Diagnosis of Multiple Sclerosis (2001) Ann Neurol, 50, pp. 121-127. , 10.1002/ana.1032, 1145630
Johnson, K.P., Brooks, B.R., Cohen, J.A., Ford, C.C., Goldstein, J., Lisak, R.P., Myers, L.W., Schiffer, R.B., Copolymer 1 reduces relapse rate and improves disability in relapsing-remitting multiple sclerosis: results of a phase III multicenter, double-blind placebo-controlled trial (1995) Neurology, 45, pp. 1268-1276
Li, D.K., Paty, D.W., Magnetic resonance imaging results of the PRISMS trial: a randomized, double-blind, placebo-controlled study of interferon-beta1a in relapsing-remitting multiple sclerosis (1999) Ann Neurol, 46, pp. 197-206. , 10.1002/1531-8249(199908)46:2<197::AID-ANA9> 3.0.CO
Simon, J.H., Jacobs, L.D., Campion, M., Wende, K., Simonian, N., Cookfair, D.L., Rudick, R.A., Whitham, R.H., Magnetic resonance studies of intramuscular interferon beta-1a for relapsing multiple sclerosis (1998) Ann Neurol, 43, pp. 79-87. , 10.1002/ana.410430114, 9450771
Amato, M.P., Zipoli, V., Portaccio, E., Multiple sclerosis-related cognitive changes: a review of cross-sectional and longitudinal studies (2006) J Neurol Sci, 245, pp. 41-46. , 10.1016/j.jns.2005.08.019, 16643953
Glanz, B.I., Healy, B.C., Rintell, D.J., Jaffin, S.K., Bakshi, R., Weiner, H.L., The association between cognitive impairment and quality of life in patients with early multiple sclerosis (2010) J Neurol Sci, 290, pp. 75-79. , 10.1016/j.jns.2009.11.004, 19944429
Rao, S.M., Leo, G.J., Ellington, L., Nauertz, T., Bernardin, L., Unverzagt, F., Cognitive dysfunction in multiple sclerosis. II. Impact on employment and social functioning (1991) Neurology, 41, pp. 692-696
Lazeron, R.H., de Sonneville, L.M., Scheltens, P., Polman, C.H., Barkhof, F., Cognitive slowing in multiple sclerosis is strongly associated with brain volume reduction (2006) Mult Scler, 12, pp. 760-768. , 10.1177/1352458506070924, 17263004
Amato, M.P., Portaccio, E., Goretti, B., Zipoli, V., Ricchiuti, L., De Caro, M.F., Patti, F., Trojano, M., The Rao's Brief Repeatable Battery and Stroop Test: normative values with age, education and gender corrections in an Italian population (2006) Mult Scler, 12, pp. 787-793. , 10.1177/1352458506070933, 17263008
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Changes In Magnetic Resonance Imaging Disease Measures Over 3 Years In Mildly Disabled Patients With Relapsing-Remitting Multiple Sclerosis Receiving Interferon Beta-1a In The Cognitive Impairment In Multiple Sclerosis (cogimus) Study
Background: Conventional magnetic resonance imaging (MRI) has improved the diagnosis and monitoring of multiple sclerosis (MS). In clinical trials, MRI has been found to detect treatment effects with greater sensitivity than clinical measures; however, clinical and MRI outcomes tend to correlate poorly.Methods: In this observational study, patients (n = 550; 18-50 years; relapsing-remitting MS [Expanded Disability Status Scale score ≤4.0]) receiving interferon (IFN) β-1a therapy (44 or 22 μg subcutaneously [sc] three times weekly [tiw]) underwent standardized MRI, neuropsychological and quality-of-life (QoL) assessments over 3 years. In this post hoc analysis, MRI outcomes and correlations between MRI parameters and clinical and functional outcomes were analysed.Results: MRI data over 3 years were available for 164 patients. T2 lesion and T1 gadolinium-enhancing (Gd+) lesion volumes, but not black hole (BH) volumes, decreased significantly from baseline to Year 3 (P < 0.0001). Percentage decreases (baseline to Year 3) were greater with the 44 μg dose than with the 22 μg dose for T2 lesion volume (-10.2% vs -4.5%, P = 0.025) and T1 BH volumes (-7.8% vs +10.3%, P = 0.002). A decrease in T2 lesion volume over 3 years predicted stable QoL over the same time period. Treatment with IFN β-1a, 44 μg sc tiw, predicted an absence of cognitive impairment at Year 3.Conclusion: Subcutaneous IFN β-1a significantly decreased MRI measures of disease, with a significant benefit shown for the 44 μg over the 22 μg dose; higher-dose treatment also predicted better cognitive outcomes over 3 years. © 2011 Bastianello et al; licensee BioMed Central Ltd.
Background: Conventional magnetic resonance imaging (MRI) has improved the diagnosis and monitoring of multiple sclerosis (MS). In clinical trials, MRI has been found to detect treatment effects with greater sensitivity than clinical measures; however, clinical and MRI outcomes tend to correlate poorly.Methods: In this observational study, patients (n = 550; 18-50 years; relapsing-remitting MS [Expanded Disability Status Scale score ≤4.0]) receiving interferon (IFN) β-1a therapy (44 or 22 μg subcutaneously [sc] three times weekly [tiw]) underwent standardized MRI, neuropsychological and quality-of-life (QoL) assessments over 3 years. In this post hoc analysis, MRI outcomes and correlations between MRI parameters and clinical and functional outcomes were analysed.Results: MRI data over 3 years were available for 164 patients. T2 lesion and T1 gadolinium-enhancing (Gd+) lesion volumes, but not black hole (BH) volumes, decreased significantly from baseline to Year 3 (P < 0.0001). Percentage decreases (baseline to Year 3) were greater with the 44 μg dose than with the 22 μg dose for T2 lesion volume (-10.2% vs -4.5%, P = 0.025) and T1 BH volumes (-7.8% vs +10.3%, P = 0.002). A decrease in T2 lesion volume over 3 years predicted stable QoL over the same time period. Treatment with IFN β-1a, 44 μg sc tiw, predicted an absence of cognitive impairment at Year 3.Conclusion: Subcutaneous IFN β-1a significantly decreased MRI measures of disease, with a significant benefit shown for the 44 μg over the 22 μg dose; higher-dose treatment also predicted better cognitive outcomes over 3 years. © 2011 Bastianello et al; licensee BioMed Central Ltd.
Changes In Magnetic Resonance Imaging Disease Measures Over 3 Years In Mildly Disabled Patients With Relapsing-Remitting Multiple Sclerosis Receiving Interferon Beta-1a In The Cognitive Impairment In Multiple Sclerosis (cogimus) Study
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Changes In Magnetic Resonance Imaging Disease Measures Over 3 Years In Mildly Disabled Patients With Relapsing-Remitting Multiple Sclerosis Receiving Interferon Beta-1a In The Cognitive Impairment In Multiple Sclerosis (cogimus) Study
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Impact Factor: 3.408
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Patti F, De Stefano M, Lavorgna L, Messina S, Chisari CG, Ippolito D, Lanzillo R, Vacchiano V, Realmuto S, Valentino P, Coniglio G, Buccafusca M, Paolicelli D, D'Ambrosio A, Montella P, Morra VB, Savettieri G, Alfano B, Gallo A, Simone I, Viterbo R, Zappia M, Bonavita S, Tedeschi G
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Giua R, Pedone C, Scarlata S, Carrozzo I, Rossi FF, Valiani V, Incalzi RA
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Squeglia F, Bachert B, De Simone A, Lukomski S, Berisio R
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Impact Factor: 8.185
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Molino I, Cavaliere C, Salvatore E, Quarantelli M, Colucci L, Fasanaro AM
* Is anterior communicating artery syndrome related to fornix lesions? (289 views)
J Alzheimers Dis (ISSN: 1387-2877, 1387-2877linking), 2014; 42Suppl3: S199-S199.
Impact Factor: 4.151
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Quadri M, Fang M, Picillo M, Olgiati S, Breedveld Gj Graafland J, Wu B, Xu F, Erro R, Amboni M, Pappata S, Quarantelli M, Annesi G, Quattrone A, Chien Hf Barbosa ER, International Parkinsonism Genetics Network Oostra Ba Barone P, Wang J, Bonifati V
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Impact Factor: 5.122
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Lanzillo R, Bonavita S, Quarantelli M, Vacca G, Lus G, Amato L, Carotenuto A, Tedeschi G, Orefice G, Brescia Morra V
* Natalizumab is effective in multiple sclerosis patients switching from other disease modifying therapies in clinical practice (312 views)
Neurol Sci (ISSN: 1590-1874, 1590-0187, 1590-3478), 2013 Apr; 34(4): 521-528.
Impact Factor: 0.38
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Lanzillo R, Quarantelli M, Bonavita S, Ventrella G, Lus G, Vacca G, Prinster A, Orefice G, Tedeschi G, Brescia Morra V
* Natalizumab vs interferon beta 1a in relapsing-remitting multiple sclerosis: A head-to-head retrospective study (400 views)
Acta Neurol Scand (ISSN: 0001-6314, 1600-0404), 2012 Nov; 126(5): 306-314.
Impact Factor: 2.474
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Caraci F, Battaglia G, Sortino MA, Spampinato S, Molinaro G, Copani A, Nicoletti F, Bruno V
* Metabotropic glutamate receptors in neurodegeneration/neuroprotection: Still a hot topic? (626 views)
Neurochem Int (ISSN: 0197-0186), 2012 Sep; 61(4): 559-565.
Impact Factor: 2.659
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Caraci F, Spampinato S, Sortino MA, Bosco P, Battaglia G, Bruno V, Drago F, Nicoletti F, Copani A
* Dysfunction of TGF-β1 signaling in Alzheimer's disease: Perspectives for neuroprotection (972 views)
Cell Tissue Res (ISSN: 0302-766x), 2012 Jan; 347(1): 291-301.
Impact Factor: 3.677
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Pappata S, Santangelo G, Aarsland D, Vicidomini C, Longo K, Bronnick K, Amboni M, Erro R, Vitale C, Caprio MG, Pellecchia MT, Brunetti A, De Michele G, Salvatore M, Barone P
* Mild cognitive impairment in drug-naive patients with PD is associated with cerebral hypometabolism (486 views)
Neurology (ISSN: 0028-3878, 1526-632x, 1526-632xelectronic), 2011 Oct 4; 77(14): 1357-1362.
Impact Factor: 8.312
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Bellia F, Vecchio G, Cuzzocrea S, Calabrese V, Rizzarelli E
* Neuroprotective features of carnosine in oxidative driven diseases (424 views)
Molecular Aspects Of Medicine (ISSN: 1872-9452, 0098-2997), 2011 Sep; 32(4-6): 258-266.
Impact Factor: 9.97
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Lanzillo R, Orefice G, Prinster A, Ventrella G, Liuzzi R, Scarano V, Florio C, Vacca G, Brunetti A, Alfano B, Brescia Morra V, Bonavita V
* Predictive factors of neutralizing antibodies development in relapsing-remitting multiple sclerosis patients on interferon Beta-1b therapy (314 views) (PDF 221 views)
Neurol Sci (ISSN: 1590-1874, 1590-3478, 1590-1874linking), 2011 Apr; 32(2): 287-292.
Impact Factor: 1.315
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Corona C, Frazzini V, Silvestri E, Lattanzio R, La Sorda R, Piantelli M, Canzoniero LM, Ciavardelli D, Rizzarelli E, Sensi SL
* Effects of dietary supplementation of carnosine on mitochondrial dysfunction, amyloid pathology, and cognitive deficits in 3xTg-AD mice (553 views)
Plosone (ISSN: 1932-6203, 1932-6203electronic, 1932-6203linking), 2011 Mar 15; 6(3): e17971-e17971.
Impact Factor: 4.092
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Santoro L, Breedveld GJ, Manganelli F, Iodice R, Pisciotta C, Nolano M, Punzo F, Quarantelli M, Pappata S, Di Fonzo A, Oostra BA, Bonifati V
* Novel ATP13A2 (PARK9) homozygous mutation in a family with marked phenotype variability (368 views)
Neurogenetics (ISSN: 1364-6745, 1364-6753, 1364-6753electronic), 2011 Feb; 12(1): 33-39.
Impact Factor: 3.354
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Salvatore E, Di Maio L, Filla A, Ferrara AM, Rinaldi C, Sacca F, Peluso S, Macchia PE, Pappata S, De Michele G
* Benign hereditary chorea: Clinical and neuroimaging features in an Italian family (356 views)
Mov Disord (ISSN: 0885-3185, 1531-8257, 0885-3185linking), 2010 Jul 30; 25(10): 1491-1496.
Impact Factor: 4.48
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Lanzillo R, Orefice G, Quarantelli M, Rinaldi C, Prinster A, Ventrella G, Spitaleri D, Lus G, Vacca G, Carotenuto B, Salvatore E, Brunetti A, Tedeschi G, Brescia Morra V
* Atorvastatin combined to interferon to verify the efficacy (ACTIVE) in relapsing-remitting active multiple sclerosis patients: A longitudinal controlled trial of combination therapy (559 views)
Mult Scler (ISSN: 1352-4585, 1477-0970, 1352-4585linking), 2010 Apr; 16(4): 450-454.
Impact Factor: 4.23
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Vitiello M, Finamore E, Falanga A, Raieta K, Cantisani M, Galdiero F, Pedone C, Galdiero M, Galdiero S
* Viral fusion peptides induce several signal transduction pathway activations that are essential for interleukin-10 and beta-interferon production (476 views)
Intervirology (ISSN: 1423-0100, 0300-5526), 2010; 53(6): 381-389.
Impact Factor: 1.756
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Postiglione A, Milan G, Pappata S, De Falco C, Lamenza F, Schiattarella V, Gallotta G, Sorrentino P, Striano S
* Fronto-temporal dementia presenting as Geschwind's syndrome (475 views)
Neurocase (ISSN: 1355-4794, 1465-3656), 2008; 14(3): 264-270.
Impact Factor: 0.918
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Tedeschi G, Dinacci D, Lavorgna L, Prinster A, Savettieri G, Quattrone A, Livrea P, Messina C, Reggio A, Servillo G, Bresciamorra V, Orefice G, Paciello M, Brunetti A, Paolillo A, Coniglio G, Bonavita S, Di Costanzo A, Bellacosa A, Valentino P, Quarantelli M, Patti F, Salemi G, Cammarata E, Simone I, Salvatore M, Bonavita V, Alfano B
* Correlation between fatigue and brain atrophy and lesion load in multiple sclerosis patients independent of disability (544 views) (PDF 240 views)
J Neurol Sci (ISSN: 0022-510x), 2007 Dec 15; 263(1-2): 15-19.
Impact Factor: 2.315
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Calabrese V, Mancuso C, Calvani M, Rizzarelli E, Butterfield DA, Stella AM
* Nitric oxide in the central nervous system: neuroprotection versus neurotoxicity (752 views)
Nature Reviews Neuroscience (ISSN: 1471-0048), 2007 Oct; 8(10): 766-775.
Impact Factor: 24.52
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Merolla F, Pentimalli F, Pacelli R, Vecchio G, Fusco A, Grieco M, Celetti A
* Involvement of H4(D10S170) protein in ATM-dependent response to DNA damage (606 views)
Oncogene (ISSN: 0950-9232, 1476-5594), 2007 Sep 13; 26(42): 6167-6175.
Impact Factor: 6.44
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Minopoli G, Stante M, Napolitano F, Telese F, Aloia L, De Felice M, Di Lauro R, Pacelli R, Brunetti A, Zambrano N, Russo T
* Essential roles for Fe65, Alzheimer amyloid precursor-binding protein, in the cellular response to DNA damage (522 views)
Jbc Papers (ISSN: 0021-9258, 1083-351x, 0021-9258linking), 2007 Jan 12; 282(2): 831-835.
Impact Factor: 5.581
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Serrano CM, Allegri RF, Caramelli P, Taragano FE, Camera L
* Mild cognitive impairment. Survey of attitudes of specialists and general physicians (615 views)
Medicina (ISSN: 0025-7680), 2007; 67(1): 19-25.
Impact Factor: 0.193
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Lanzillo R, Prinster A, Scarano V, Liuzzi R, Coppola G, Florio C, Salvatore E, Schiavone V, Brunetti A, Muto M, Orefice G, Alfano B, Bonavita V, Brescia Morra V
* Neuropsychological assessment, quantitative MRI and ApoE gene polymorphisms in a series of MS patients treated with IFN beta-1b (334 views) (PDF 210 views)
J Neurol Sci (ISSN: 0022-510x), 2006 Jun 15; 245(1-2): 141-145.
Impact Factor: 2.412
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Prinster A, Quarantelli M, Orefice G, Lanzillo R, Brunetti A, Mollica C, Salvatore E, Morra VB, Coppola G, Vacca G, Alfano B, Salvatore M
* Grey matter loss in relapsing-remitting multiple sclerosis: A voxel-based morphometry study (452 views) (PDF 226 views)
Neuroimage (ISSN: 1053-8119, 1053-8119linking), 2006 Feb 1; 29(3): 859-867.
Impact Factor: 5.559
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Filippo C, Mariangela C, Giuseppina F, Pier Luigi C, Angelo B, Marco C, Giuseppe B, Paolo B, Ferdinando N, Agata C, Maria Angela S
* Nicergoline, a drug used for age-dependent cognitive impairment, protects cultured neurons against β-amyloid toxicity (797 views)
Brain Res (ISSN: 0006-8993), 2005; 1047(1): 30-37.
Impact Factor: 2.296
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Varrone A, Pappata S, Caracò C, Soricelli A, Milan G, Quarantelli M, Alfano B, Postiglione A, Salvatore M
* Voxel-based comparison of rCBF SPET images in frontotemporal dementia and Alzheimer's disease highlights the involvement of different cortical networks (443 views) (PDF 309 views)
Eur J Nucl Med (ISSN: 0340-6997, 1619-7070, 1619-7089), 2002 Nov; 29(11): 1447-1454.
Impact Factor: 3.568
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Vitiello M, Finamore E, Falanga A, Raieta K, Cantisani M, Galdiero F, Pedone C, Galdiero M, Galdiero S
* Fusion in Coq (479 views)
Lecture Notes In Computer Science (ISSN: 0302-9743, 0302-974335404636319783540463634, 0302-974335402975459783540297543), 2001; 2178LNCS: 583-596.
Impact Factor: 0.415
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Renda A, Iovino F, Capasso L, Ricciardelli L, Tammaro V, Acampa W
Radioimmunoguided surgery in colorectal cancer: A 6-year experience with four different technical solutions (314 views)
Semin Surg Oncol Wiley Liss Inc (ISSN: 8756-0437), 1998 Dec; 15(4): 226-230.
Impact Factor: 1.045
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36 Records (34 excluding Abstracts).
Total impact factor: 149.812 (141.569 excluding Abstracts).
Total 5 year impact factor: 151.873 (142.971 excluding Abstracts).
Total impact factor: 149.812 (141.569 excluding Abstracts).
Total 5 year impact factor: 151.873 (142.971 excluding Abstracts).
361 views. Last view on Saturday 14 January 2023, 17:59:07
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