Functional Imaging Of Multidrug Resistant Phenotype By 99mtc-Mibi Scan In Patients With Multiple Myeloma (461 views)
Cancer Biotherapy And Radiopharmaceuticals (ISSN: 1084-9785, 1084-4978), 2004; 19(2): 165-170.
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Paper type: Journal Article,
Impact factor: 1.091, 5-year impact factor: 1.685
Url: http://www.scopus.com/inward/record.url?eid=2-s2.0-2542469508&partnerID=40&md5=fce8e8f5548ab028502de6820a289643
Keywords: 99mtc-Mibi, Multidrug Resistance, Multiple Myeloma, P-Glycoprotein, Washout, Diatrizoate, Ficoll, Methoxy Isobutyl Isonitrile Technetium Tc 99m, Monoclonal Antibody, Monoclonal Antibody C219, Unclassified Drug, Adult, Aged, Article, Bone Marrow Biopsy, Cancer Resistance, Clinical Article, Clinical Trial, Controlled Clinical Trial, Controlled Study, Female, Gene Overexpression, Human, Human Tissue, Immunocytochemistry, Phenotype, Priority Journal, Protein Expression, Radioisotope Distribution, Whole Body Scintiscanning, Diagnostic Imaging, Middle Aged, Sensitivity And Specificity, Technetium Tc 99m Sestamibi,
Affiliations:
*** IBB - CNR ***
CNR, Ist. di Biostrut. /Bioimmagini Naples, Italy
Cattedra di Ematologia, Dipto. di Med. Clin. /Sperim. Naples, Italy
Dipto. Assit. Diagn. Immagini/R., Universit Federico II, Naples, Italy
Piazzetta Mondragone 8, 80132 Naples, Italy
References:
Gottesman, M. M., Fojo, T., Bates, S. E., Multidrug resistance in cancer: Role of ATP-dependent transporters (2002) Nature, 2, p. 4
Tirovola, E. B., Biassoni, L., Britton, K. E., The use of 99mTc-MIBI scanning in multiple myeloma (1996) Br J Cancer, 74, p. 1815
Sonneveld, P., Lokhorst, H. M., Vossebeld, P., Drug resistance in multiple myeloma (1997) Semin Hematol, 34, p. 34
Adams, B. K., Fataar, A., Nizami, M. A., Technetium-99m-sestamibi uptake in myeloma (1996) J Nucl Med, 37, p. 1001
Ei-Shirbiny, A. M., Yeung, H., Imbriaco, M., Technetium-99m-MIBI versus fluorine-18-FDG in diffuse multiple myeloma (1997) J Nucl Med, 38, p. 1208
Pace, L., Catalano, L., Pinto, A. M., Different patterns of technetium-99m-sestamibi uptake in multiple myeloma (1998) Eur J Nucl Med, 25, p. 714
Catalano, L., Pace, L., Califano, C., Detection of focal myeloma lesions by technetium-99m-sestamibi scintigraphy (1999) Haematologica, 84, p. 119
Fonti, R., Del Vecchio, S., Zannetti, A., Bone marrow uptake of 99mTc-MIBI in patients with multiple myeloma (2001) Eur J Nucl Med, 28, p. 214
Piwnica-Worms, D., Kronauge, J. F., Chiu, M. L., Uptake and retention of Hexaxis (2-methoxyisobutyl isonitrile) Technetium (I) in cultured chick myocardial cells: Mitochondrial and plasma membrane potential dependence (1990) Circulation, 82, p. 1826
Delmon-Moingeon, L. I., Piwnica-Worms, D., Van Den Abbeele, A. D., Uptake of the cation Hexaxis (2-methoxyisobutylisonitrile) -technetium-99m by human carcinoma cell lines in vitro (1990) Cancer Res, 50, p. 2198
Chiu, M. L., Kronauge, J. F., Piwnica-Worms, D., Effect of mitochondrial and plasma membrane potentials on accumulation of Hexaxis (2-methoxyisobutylisonitrile) Technetium (I) in cultured mouse fibroblasts (1990) J Nucl Med, 31, p. 1646
Crankshaw, C. L., Marmion, M., Luker, G. D., Novel technetium (III) -Q complexes for functional imaging of multidrug resistance (MDR1) P-glycoprotein (1998) J Nucl Med, 39, p. 77
Del Vecchio, S., Ciarmiello, A., Pace, L., Washout of technetium-99m-sestamibi as an index of P-glycoprotein expression in untreated breast cancer patients (1997) J Nucl Med, 38, p. 1348
Kostakoglu, L., Guc, D., Canpinar, H., P-glycoprotein expression by technetium-99m-MIBI scintigraphy in hematologic malignancy (1998) J Nucl Med, 39, p. 1191
Burak, Z., Ersoy, O., Moretti, J. L., The role of 99mTc-MIBI scintigraphy in the assessment of MDR1 overexpression in patients with musculoskeletal sarcomas: Comparison with therapy response (2001) Eur J Nucl Med, 28, p. 1341
Sun, S. S., Shiau, Y. C., Lin, C. C., Correlation between P-glycoprotein (Pgp) expression in parathyroid and Tc-99m-MIBI parathyroid image findings (2001) Nucl Med Biol, 28, p. 929
Yuksel, M., Cermik, F., Doganay, L., 99mTc-MIBI SPET in non-small cell lung cancer in relationship with Pgp and prognosis (2002) Eur J Nucl Med Mol Imaging, 29, p. 876
Fitzgerald, M. G., Hosking, C. S., Cell structure and percent viability by a slide centrifuge technique (1982) J Clin Pathol, 35, p. 191
Hsu, S. M., Raine, L., Fanger, H., Use of avidin-biotin-peroxidase complex (ABC) in immunoperoxidase techniques: A comparison between ABC and unlabeled antibody (PAP) procedures (1981) Histochem Cytochem, 29, p. 577
Sonneveld, P., Segeren, C. M., Changing concepts in multiple myeloma: From conventional chemotherapy to high-dose treatment (2003) Eur J Cancer, 39, p. 9
Marie, J. P., Zhou, D. C., Gurbuxani, S., MDR1/P-glycoprotein in haematological neoplasms (1996) Eur J Cancer, 32, p. 1034
Mongkonsritragoon, W., Kimlinger, T., Ahmann, G., Is multidrug resistance (P-glycoprotein) an intrinsic characteristic of plasma cells in patients with monoclonal gammopathy of undetermined significance, plasmacytoma, multiple myeloma, and amyloidosis? (1998) Leuk Lymphoma, 29, p. 577
Perez-Simon, J. A., Valverde, B., Martinez, A., Correlation of rhodamine 123 efflux by neoplastic plasma cells with clinical and biological characteristics of multiple myeloma (1999) Cytometry, 38, p. 24
Covelli, A., Modulation of multidrug resistance (MDR) in hematological malignancies (1999) Ann Oncol, 6, p. 53
Sonneveld, P., Suciu, S., Weijermans, P., Cyclosporin A combined with vincristine, doxorubicin, and dexamethasone (VAD) compared with VAD alone in patients with advanced refractory multiple myeloma: An EORTC-HOVON randomized phase III study (2001) Br J Haematol, 115, p. 895
Gottesman, M.M., Fojo, T., Bates, S.E., Multidrug resistance in cancer: Role of ATP-dependent transporters (2002) Nature, 2, p. 4
Tirovola, E.B., Biassoni, L., Britton, K.E., The use of 99mTc-MIBI scanning in multiple myeloma (1996) Br J Cancer, 74, p. 1815
Adams, B.K., Fataar, A., Nizami, M.A., Technetium-99m-sestamibi uptake in myeloma (1996) J Nucl Med, 37, p. 1001
Ei-Shirbiny, A.M., Yeung, H., Imbriaco, M., Technetium-99m-MIBI versus fluorine-18-FDG in diffuse multiple myeloma (1997) J Nucl Med, 38, p. 1208
Chiu, M.L., Kronauge, J.F., Piwnica-Worms, D., Effect of mitochondrial and plasma membrane potentials on accumulation of Hexaxis (2-methoxyisobutylisonitrile) Technetium (I) in cultured mouse fibroblasts (1990) J Nucl Med, 31, p. 1646
Crankshaw, C.L., Marmion, M., Luker, G.D., Novel technetium (III)-Q complexes for functional imaging of multidrug resistance (MDR1) P-glycoprotein (1998) J Nucl Med, 39, p. 77
Sun, S.S., Shiau, Y.C., Lin, C.C., Correlation between P-glycoprotein (Pgp) expression in parathyroid and Tc-99m-MIBI parathyroid image findings (2001) Nucl Med Biol, 28, p. 929
Fitzgerald, M.G., Hosking, C.S., Cell structure and percent viability by a slide centrifuge technique (1982) J Clin Pathol, 35, p. 191
Hsu, S.M., Raine, L., Fanger, H., Use of avidin-biotin-peroxidase complex (ABC) in immunoperoxidase techniques: A comparison between ABC and unlabeled antibody (PAP) procedures (1981) Histochem Cytochem, 29, p. 577
Marie, J.P., Zhou, D.C., Gurbuxani, S., MDR1/P-glycoprotein in haematological neoplasms (1996) Eur J Cancer, 32, p. 1034
Perez-Simon, J.A., Valverde, B., Martinez, A., Correlation of rhodamine 123 efflux by neoplastic plasma cells with clinical and biological characteristics of multiple myeloma (1999) Cytometry, 38, p. 24
Cancer Biotherapy And Radiopharmaceuticals (ISSN: 1084-9785, 1084-4978), 2004; 19(2): 165-170.
Export to BibTeX Export to EndNote
Paper type: Journal Article,
Impact factor: 1.091, 5-year impact factor: 1.685
Url: http://www.scopus.com/inward/record.url?eid=2-s2.0-2542469508&partnerID=40&md5=fce8e8f5548ab028502de6820a289643
Keywords: 99mtc-Mibi, Multidrug Resistance, Multiple Myeloma, P-Glycoprotein, Washout, Diatrizoate, Ficoll, Methoxy Isobutyl Isonitrile Technetium Tc 99m, Monoclonal Antibody, Monoclonal Antibody C219, Unclassified Drug, Adult, Aged, Article, Bone Marrow Biopsy, Cancer Resistance, Clinical Article, Clinical Trial, Controlled Clinical Trial, Controlled Study, Female, Gene Overexpression, Human, Human Tissue, Immunocytochemistry, Phenotype, Priority Journal, Protein Expression, Radioisotope Distribution, Whole Body Scintiscanning, Diagnostic Imaging, Middle Aged, Sensitivity And Specificity, Technetium Tc 99m Sestamibi,
Affiliations:
*** IBB - CNR ***
CNR, Ist. di Biostrut. /Bioimmagini Naples, Italy
Cattedra di Ematologia, Dipto. di Med. Clin. /Sperim. Naples, Italy
Dipto. Assit. Diagn. Immagini/R., Universit Federico II, Naples, Italy
Piazzetta Mondragone 8, 80132 Naples, Italy
References:
Gottesman, M. M., Fojo, T., Bates, S. E., Multidrug resistance in cancer: Role of ATP-dependent transporters (2002) Nature, 2, p. 4
Tirovola, E. B., Biassoni, L., Britton, K. E., The use of 99mTc-MIBI scanning in multiple myeloma (1996) Br J Cancer, 74, p. 1815
Sonneveld, P., Lokhorst, H. M., Vossebeld, P., Drug resistance in multiple myeloma (1997) Semin Hematol, 34, p. 34
Adams, B. K., Fataar, A., Nizami, M. A., Technetium-99m-sestamibi uptake in myeloma (1996) J Nucl Med, 37, p. 1001
Ei-Shirbiny, A. M., Yeung, H., Imbriaco, M., Technetium-99m-MIBI versus fluorine-18-FDG in diffuse multiple myeloma (1997) J Nucl Med, 38, p. 1208
Pace, L., Catalano, L., Pinto, A. M., Different patterns of technetium-99m-sestamibi uptake in multiple myeloma (1998) Eur J Nucl Med, 25, p. 714
Catalano, L., Pace, L., Califano, C., Detection of focal myeloma lesions by technetium-99m-sestamibi scintigraphy (1999) Haematologica, 84, p. 119
Fonti, R., Del Vecchio, S., Zannetti, A., Bone marrow uptake of 99mTc-MIBI in patients with multiple myeloma (2001) Eur J Nucl Med, 28, p. 214
Piwnica-Worms, D., Kronauge, J. F., Chiu, M. L., Uptake and retention of Hexaxis (2-methoxyisobutyl isonitrile) Technetium (I) in cultured chick myocardial cells: Mitochondrial and plasma membrane potential dependence (1990) Circulation, 82, p. 1826
Delmon-Moingeon, L. I., Piwnica-Worms, D., Van Den Abbeele, A. D., Uptake of the cation Hexaxis (2-methoxyisobutylisonitrile) -technetium-99m by human carcinoma cell lines in vitro (1990) Cancer Res, 50, p. 2198
Chiu, M. L., Kronauge, J. F., Piwnica-Worms, D., Effect of mitochondrial and plasma membrane potentials on accumulation of Hexaxis (2-methoxyisobutylisonitrile) Technetium (I) in cultured mouse fibroblasts (1990) J Nucl Med, 31, p. 1646
Crankshaw, C. L., Marmion, M., Luker, G. D., Novel technetium (III) -Q complexes for functional imaging of multidrug resistance (MDR1) P-glycoprotein (1998) J Nucl Med, 39, p. 77
Del Vecchio, S., Ciarmiello, A., Pace, L., Washout of technetium-99m-sestamibi as an index of P-glycoprotein expression in untreated breast cancer patients (1997) J Nucl Med, 38, p. 1348
Kostakoglu, L., Guc, D., Canpinar, H., P-glycoprotein expression by technetium-99m-MIBI scintigraphy in hematologic malignancy (1998) J Nucl Med, 39, p. 1191
Burak, Z., Ersoy, O., Moretti, J. L., The role of 99mTc-MIBI scintigraphy in the assessment of MDR1 overexpression in patients with musculoskeletal sarcomas: Comparison with therapy response (2001) Eur J Nucl Med, 28, p. 1341
Sun, S. S., Shiau, Y. C., Lin, C. C., Correlation between P-glycoprotein (Pgp) expression in parathyroid and Tc-99m-MIBI parathyroid image findings (2001) Nucl Med Biol, 28, p. 929
Yuksel, M., Cermik, F., Doganay, L., 99mTc-MIBI SPET in non-small cell lung cancer in relationship with Pgp and prognosis (2002) Eur J Nucl Med Mol Imaging, 29, p. 876
Fitzgerald, M. G., Hosking, C. S., Cell structure and percent viability by a slide centrifuge technique (1982) J Clin Pathol, 35, p. 191
Hsu, S. M., Raine, L., Fanger, H., Use of avidin-biotin-peroxidase complex (ABC) in immunoperoxidase techniques: A comparison between ABC and unlabeled antibody (PAP) procedures (1981) Histochem Cytochem, 29, p. 577
Sonneveld, P., Segeren, C. M., Changing concepts in multiple myeloma: From conventional chemotherapy to high-dose treatment (2003) Eur J Cancer, 39, p. 9
Marie, J. P., Zhou, D. C., Gurbuxani, S., MDR1/P-glycoprotein in haematological neoplasms (1996) Eur J Cancer, 32, p. 1034
Mongkonsritragoon, W., Kimlinger, T., Ahmann, G., Is multidrug resistance (P-glycoprotein) an intrinsic characteristic of plasma cells in patients with monoclonal gammopathy of undetermined significance, plasmacytoma, multiple myeloma, and amyloidosis? (1998) Leuk Lymphoma, 29, p. 577
Perez-Simon, J. A., Valverde, B., Martinez, A., Correlation of rhodamine 123 efflux by neoplastic plasma cells with clinical and biological characteristics of multiple myeloma (1999) Cytometry, 38, p. 24
Covelli, A., Modulation of multidrug resistance (MDR) in hematological malignancies (1999) Ann Oncol, 6, p. 53
Sonneveld, P., Suciu, S., Weijermans, P., Cyclosporin A combined with vincristine, doxorubicin, and dexamethasone (VAD) compared with VAD alone in patients with advanced refractory multiple myeloma: An EORTC-HOVON randomized phase III study (2001) Br J Haematol, 115, p. 895
Gottesman, M.M., Fojo, T., Bates, S.E., Multidrug resistance in cancer: Role of ATP-dependent transporters (2002) Nature, 2, p. 4
Tirovola, E.B., Biassoni, L., Britton, K.E., The use of 99mTc-MIBI scanning in multiple myeloma (1996) Br J Cancer, 74, p. 1815
Adams, B.K., Fataar, A., Nizami, M.A., Technetium-99m-sestamibi uptake in myeloma (1996) J Nucl Med, 37, p. 1001
Ei-Shirbiny, A.M., Yeung, H., Imbriaco, M., Technetium-99m-MIBI versus fluorine-18-FDG in diffuse multiple myeloma (1997) J Nucl Med, 38, p. 1208
Chiu, M.L., Kronauge, J.F., Piwnica-Worms, D., Effect of mitochondrial and plasma membrane potentials on accumulation of Hexaxis (2-methoxyisobutylisonitrile) Technetium (I) in cultured mouse fibroblasts (1990) J Nucl Med, 31, p. 1646
Crankshaw, C.L., Marmion, M., Luker, G.D., Novel technetium (III)-Q complexes for functional imaging of multidrug resistance (MDR1) P-glycoprotein (1998) J Nucl Med, 39, p. 77
Sun, S.S., Shiau, Y.C., Lin, C.C., Correlation between P-glycoprotein (Pgp) expression in parathyroid and Tc-99m-MIBI parathyroid image findings (2001) Nucl Med Biol, 28, p. 929
Fitzgerald, M.G., Hosking, C.S., Cell structure and percent viability by a slide centrifuge technique (1982) J Clin Pathol, 35, p. 191
Hsu, S.M., Raine, L., Fanger, H., Use of avidin-biotin-peroxidase complex (ABC) in immunoperoxidase techniques: A comparison between ABC and unlabeled antibody (PAP) procedures (1981) Histochem Cytochem, 29, p. 577
Marie, J.P., Zhou, D.C., Gurbuxani, S., MDR1/P-glycoprotein in haematological neoplasms (1996) Eur J Cancer, 32, p. 1034
Perez-Simon, J.A., Valverde, B., Martinez, A., Correlation of rhodamine 123 efflux by neoplastic plasma cells with clinical and biological characteristics of multiple myeloma (1999) Cytometry, 38, p. 24
Functional Imaging Of Multidrug Resistant Phenotype By 99mtc-Mibi Scan In Patients With Multiple Myeloma
Overexpression of P-glycoprotein (Pgp) is one of the primary mechanisms of multidrug resistance (MDR) in several diseases, including multiple myeloma. The aim of this study was to investigate whether the washout of Tc-99m-MIBI, a transport substrate of Pgp, is enhanced in the bone marrow of patients with multiple myeloma overexpressing Pgp. Seventeen (17) patients were i. v. injected with 555 MBq of Tc-99m-MIBI, and whole-body scans were performed at 10 and 60 minutes. A region of interest (ROI) was drawn over the thoracic spine of each scan, and the washout of 99mTc-MIBI was calculated, after decay correction, as: (10-minute counts/pixel minus 60-minute counts/pixel) divided by 10-minute counts/pixel. Pgp expression was determined in 17 bone marrow samples obtained from the same patients immediately before the Tc-99m-MIBI scan. Following centrifugation over the Ficoll-Hypaque gradient, cytospins were obtained and immunostained with C219 monoclonal antibody. The immunostaining of Pgp was graded as 1, 2, or 3 when a faint, moderate, or intense reaction, respectively, was observed in infiltrating plasma cells. Washout of Tc-99m-MIBI ranged between 5% and 26%. A statistically significant direct correlation was found between the washout of the tracer and Pgp expression (Spearman rank correlation coefficient r = 0. 74, p < 0. 001). A partial overlap of washout values was observed in different classes of Pgp expression, thus preventing the discrimination of individual patients. Washout of Tc-99m-MIBI, expressed as the percentage of radioactivity cleared from the bone marrow over a 1-hour period, may be used as a noninvasive tool for in vivo whole-body imaging of Pgp expression and function in multiple myeloma patients
Overexpression of P-glycoprotein (Pgp) is one of the primary mechanisms of multidrug resistance (MDR) in several diseases, including multiple myeloma. The aim of this study was to investigate whether the washout of Tc-99m-MIBI, a transport substrate of Pgp, is enhanced in the bone marrow of patients with multiple myeloma overexpressing Pgp. Seventeen (17) patients were i. v. injected with 555 MBq of Tc-99m-MIBI, and whole-body scans were performed at 10 and 60 minutes. A region of interest (ROI) was drawn over the thoracic spine of each scan, and the washout of 99mTc-MIBI was calculated, after decay correction, as: (10-minute counts/pixel minus 60-minute counts/pixel) divided by 10-minute counts/pixel. Pgp expression was determined in 17 bone marrow samples obtained from the same patients immediately before the Tc-99m-MIBI scan. Following centrifugation over the Ficoll-Hypaque gradient, cytospins were obtained and immunostained with C219 monoclonal antibody. The immunostaining of Pgp was graded as 1, 2, or 3 when a faint, moderate, or intense reaction, respectively, was observed in infiltrating plasma cells. Washout of Tc-99m-MIBI ranged between 5% and 26%. A statistically significant direct correlation was found between the washout of the tracer and Pgp expression (Spearman rank correlation coefficient r = 0. 74, p < 0. 001). A partial overlap of washout values was observed in different classes of Pgp expression, thus preventing the discrimination of individual patients. Washout of Tc-99m-MIBI, expressed as the percentage of radioactivity cleared from the bone marrow over a 1-hour period, may be used as a noninvasive tool for in vivo whole-body imaging of Pgp expression and function in multiple myeloma patients
Functional Imaging Of Multidrug Resistant Phenotype By 99mtc-Mibi Scan In Patients With Multiple Myeloma
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Functional Imaging Of Multidrug Resistant Phenotype By 99mtc-Mibi Scan In Patients With Multiple Myeloma
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Fonti R, Salvatore B, Quarantelli M, Sirignano C, Segreto S, Petruzziello F, Catalano L, Liuzzi R, Rotoli B, Del Vecchio S, Pace L, Salvatore M
* F-18-FDG PET/CT, Tc-99m-MIBI, and MRI in evaluation of patients with multiple myeloma (544 views)
J Nucl Med (ISSN: 0161-5505, 0161-1550, 1535-5667), 2008 Feb; 49(2): 195-200.
Impact Factor: 6.662
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Fonti R, Salvatore B, Ricci F, Petruzziello F, Catalano L, Rotoli B, Del Vecchio S, Pace L, Salvatore M
* 18F-FDG-PET/CT in the evaluation of bone marrow infiltration in patients with multiple myeloma (288 views)
Eur J Nucl Med (ISSN: 1619-7070, 1619-7089, 0340-6997), 2007 Oct; 34: N/D-N/D.
Impact Factor: 4.101
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Fonti R, Salvatore B, Ricci F, Petruzziello F, Catalano L, Del Vecchio S, Pace L, Salvatore M, Rotoli B
* F-18-FDG-PET/CT in the evaluation of bone marrow infiltration in patients with multiple myeloma (235 views)
Haematologica (ISSN: 0390-6078, 0006-4971, 0006-6497), 2007 Oct; 92: N/D-N/D.
Impact Factor: 5.516
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Fonti R, Salvatore B, Ricci F, Petruzziello F, Catalano L, Del Vecchio S, Pace L, Salvatore M, Rotoli B
* F-18-FDG-PET/CT, 99mTC-MIBI and MRI in the evaluation of patients with multiple myeloma (350 views)
Haematologica (ISSN: 0390-6078, 0006-4971, 0006-6497), 2007 Oct; 92: N/D-N/D.
Impact Factor: 5.516
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Del Vecchio S, Zannetti A, Fonti R, Pace L, Salvatore M
* Nuclear imaging in cancer theranostics (615 views)
Q J Nucl Med Mol Im (ISSN: 1824-4785, 1824-4478, 1824-4785linking), 2007 Jun; 51(2): 152-163.
Impact Factor: 1.724
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Catalano L, Del Vecchio S, Petruzziello F, Fonti R, Salvatore B, Martorelli C, Califano C, Caparrotti G, Segreto S, Pace L, Rotoli B
* Sestamibi and FDG-PET scans to support diagnosis of jaw osteonecrosis (407 views)
Ann Hematol (ISSN: 0939-5555, 0939-5555linking), 2007 Jun; 86(6): 415-423.
Impact Factor: 2.342
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Fonti R, Salvatore B, Quarantelli M, Sirignano C, Segreto S, Petruzziello F, Catalano L, Rotoli B, Del Vecchio S, Pace L, Salvatore M
* Multimodality Imaging With 18f-Fdg-Pet/Ct, 99mtc-Mibi And Mri Of Multiple Myeloma (321 views)
Proceedings Of The 2nd International Conference Of The European Society For Molecular Imaging Naples Italy, 2007; N/D: 56-56.
Impact Factor: 0
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Fonti R, Salvatore B, Quarantelli M, Sirignano C, Cammarano F, Segreto S, Petruzziello F, Catalano L, Rotoli B, Del Vecchio S, Pace L, Salvatore M
* 18F-FDG-PET/CT, 99mTc-MIBI and MRI in the evaluation of patients with multiple myeloma (397 views)
Eur J Nucl Med (ISSN: 1619-7070, 1619-7089, 0340-6997), 2006 Sep; 33: N/D-N/D.
Impact Factor: 4.041
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Del Vecchio S, Zannetti A, Iommelli F, Papaccioli A, Sommella J, Ferraro P, Baiano A, Salvatore M
* In vivo detection of early tumor response to tyrosine kinase inhibitors by microSPECT with 99mTc-MIBI (403 views)
Eur J Nucl Med (ISSN: 1619-7070, 1619-7089, 0340-6997), 2006 Sep; 33: N/D-N/D.
Impact Factor: 4.041
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Pace L, Salvatore M, Del Vecchio S
* Use of Tc-99m-Sestamibi scintigraphy in multiple myeloma (241 views)
J Nucl Med (ISSN: 1535-5667, 0161-5505, 1535-5667electronic), 2006 Mar; 47(3): 555-555.
Impact Factor: 4.986
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Fonti R, Salvatore B, Quarantelli M, Sirignano C, Cammarano F, Segreto S, Petruzziello F, Catalano L, Martinelli V, Rotoli B, Del Vecchio S, Pace L, Salvatore M
* 18f-Fdg-Pet/Ct, 99mtc-Mibi And Mri Inpatients With Multiple Myeloma (352 views)
Multimodality Imaging With Proceedings Of The Ix Congress Of The Italian Society Of Experimental Hematology, 2006; PO164: 53-53.
Impact Factor: 0
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Del Vecchio S, Zannetti A, Salvatore B, Paone G, Fonti R, Salvatore M
* Functional imaging of multidrug resistance in breast cancer (408 views)
Phys Med (ISSN: 1120-1797, 1120-1797linking), 2006; 21(SUPPL.1): 24-27.
Impact Factor: 0.313
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Del Vecchio S, Zannetti A, Fonti R, Iommelli F, Sommella I, Potena A, Salvatore M
* 99mTc-MIBI uptake in Bcl-2 overexpressing breast cancer cells during treatment with gefitinib, a selective tyrosine kinase inhibitor (380 views)
Eur J Nucl Med (ISSN: 1619-7070, 1619-7089, 0340-6997), 2005 Sep; 32: N/D-N/D.
Impact Factor: 3.883
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Catalano L, Andretta C, Pace L, Del Vecchio S, Salvatore B, De Rosa G, Buonanno MT, Paone G, Rotoli B
* Tc 99-Sesta Mibi Uptake In Nonsecretory Multiple Myeloma (354 views)
Hematology (ISSN: 1024-5332), 2005 Sep; 10(4): 335-338.
Impact Factor: 1.189
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Pace L, Catalano L, Del Vecchio S, De Renzo A, Fonti R, Salvatore B, Andretta C, Di Nuzzo C, Rotoli B, Salvatore M
* Washout of [99mTc] sestamibi in predicting response to chemotherapy in patients with multiple myeloma (381 views)
Q J Nucl Med Mol Im (ISSN: 1824-4785, 1824-4478, 1824-4785linking), 2005 Sep; 49(3): 281-285.
Impact Factor: 1.724
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Pace L, Del Vecchio S, Salvatore M
* Technetium 99m sestamibi in multiple myeloma (272 views)
Radiology (ISSN: 0033-8419, 1527-1315, 1527-1315electronic), 2005 Jan; 234(1): 312-313.
Impact Factor: 5.377
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Zannetti A, Del Vecchio S, Fonti R, Iommelli F, Sommella J, Potena A, Salvatore M
* Gefitinib, A Selective, Tyrosine Kinase Inhibitor Increases 99mtc-Mibi Uptake In Bcl-2 Overexpressing Breast Cancer Cells (380 views)
Mol Immunol, 2005; 4: 355-355.
Impact Factor: 3.003
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Pace L, Del Vecchio S, Salvatore M, Walker RC, Angtuaco E, Sethi R, Fassas A, Barlogie B
* Technetium 99m sestamibi in multiple myeloma [3] (multiple letters) (339 views)
Radiology (ISSN: 0033-8419, 1527-1315, 1527-1315electronic), 2005; 234(1): 312-313.
Impact Factor: 5.377
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Del Vecchio S, Zannetti A, Salvatore B, Paone G, Fonti R, Iommelli F, De Renzo A, Rotoli B, Salvatore M
* 99mTc-MIBI uptake in Bcl-2 overexpressing non-Hodgkin's lymphoma patients during drug-induced apoptosis (353 views)
Eur J Nucl Med (ISSN: 1619-7070, 1619-7089, 0340-6997), 2004 Sep; 31: N/D-N/D.
Impact Factor: 3.935
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Del Vecchio S, Salvatore M
* Tc-99m-MIBI in the evaluation of breast cancer biology (598 views) (PDF 182 views)
Eur J Nucl Med (ISSN: 1619-7070, 1619-7089, 0340-6997), 2004 Jun; 31(SUPPL.1): S88-S88.
Impact Factor: 3.935
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Aloj L, Zannetti A, Caracó C, Del Vecchio S, Salvatore M
* Bcl-2 overexpression prevents 99mTc-MIBI uptake in breast cancer cell lines (555 views)
Eur J Nucl Med (ISSN: 1619-7070, 1619-7089, 0340-6997), 2004; 31(4): 521-527.
Impact Factor: 3.935
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Pace L, Salvatore M, Del Vecchio S
* A new role for nuclear medicine in multiple Myeloma (321 views)
J Nucl Med (ISSN: 0161-5505, 1535-5667, 1535-5667electronic), 2003 Sep; 44(8): 1369-1369.
Impact Factor: 4.899
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Andretta C, Catalano L, Pace L, Fonti R, Annunziata G, Rotoli B
* 99mTc-sestaMIBI scintigraphy in thalidomide-treated refractory or relapsed multiple myeloma patients [2] (290 views)
Leuk Lymphoma (ISSN: 1042-8194, 1026-8022linking), 2003 Jun; 44(6): 1081-1082.
Impact Factor: 1.163
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Del Vecchio S, Zannetti A, Aloj L, Caracò C, Ciarmiello A, Salvatore M
* Inhibition of early Tc-99m-MIBI uptake by Bcl-2 anti-apoptotic protein overexpression in untreated breast carcinoma (524 views)
Eur J Nucl Med (ISSN: 1619-7070, 1619-7089, 0340-6997), 2003 Jun; 30(6): 879-887.
Impact Factor: 3.324
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Del Vecchio S, Zannetti A, Aloj L, Salvatore M
* MIBI as prognostic factor in breast cancer (459 views)
Q J Nucl Med (ISSN: 1124-3937, 1125-0135), 2003 Mar; 47(1): 46-50.
Impact Factor: 2.222
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Del Vecchio S, Zannetti A, Ciarmiello A, Aloj L, Caracò C, Fonti R, Botti G, D'Aiuto G, Salvatore M
* Dynamic coupling of Tc-99m-MIBI efflux and apoptotic pathway activation in untreated breast cancer patients (481 views)
Eur J Nucl Med (ISSN: 1619-7070, 0340-6997, 1619-7089), 2002 Jun; 29(6): 809-814.
Impact Factor: 3.568
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Marino M, Rossi M, Ruvo M, Fassina G
* Novel molecular targets for systemic lupus erythematosus (369 views)
Curr Drug Targets (ISSN: 1389-4501), 2002 Jun; 3(3): 223-228.
Impact Factor: 3.597
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Del Vecchio S, Zannetti A, Ciarmiello A, Aloj L, Fonti R, Caraco C, Salvatore M
* 99mTc-MIBI uptake and Bcl-2 overexpression in untreated breast cancer patients (368 views)
Eur J Nucl Med (ISSN: 0340-6997, 1619-7070, 1619-7089), 2001 Sep; 28(8): N/D-N/D.
Impact Factor: 3.464
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Aloj L, Zannetti A, Caraco C, Fonti R, Del Vecchio S, Salvatore M
* 99mTc-MIBI uptake in breast cancer cells during early phases of apoptosis induction with Staurosporine (370 views)
Eur J Nucl Med (ISSN: 0340-6997, 1619-7070, 1619-7089), 2001 Sep; 28(8): N/D-N/D.
Impact Factor: 3.464
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Aloj L, Del Vecchio S, Zannetti A, Caracò C, Salvatore M
* 99mTc-MIBI uptake is reduced in Bcl-2 overexpressing MCF-7 breast cancer cells (357 views)
Eur J Nucl Med (ISSN: 0340-6997, 1619-7070, 1619-7089), 2001 Sep; 28(8): N/D-N/D.
Impact Factor: 3.464
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Pace L, Catalano L, Del Vecchio S, De Renzo A, Fonti R, Sica G, Annunziata G, Califano C, Rotoli B, Salvatore M
* Wash-out of 99mTc-sestamibi (99mTc-MIBI) in evaluating response to chemotherapy in patients with multiple myeloma (MM) (305 views)
Eur J Nucl Med (ISSN: 0340-6997, 1619-7070, 1619-7089), 2001 Sep; 28(8): N/D-N/D.
Impact Factor: 3.464
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Pace L, Catalano L, Del Vecchio S, Di Gennaro F, De Renzo A, Sica G, Califano C, Tedesco N, Borrelli G, Rotoli B, Salvatore M
* Predictive value of technetium-99m sestamibi in patients with multiple myeloma and potential role in the follow-up (410 views)
Eur J Nucl Med (ISSN: 0340-6997, 1619-7070, 1619-7089), 2001 Mar; 28(3): 304-312.
Impact Factor: 3.464
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Imbriaco M, Del Vecchio S, Riccardi A, Pace L, Di Salle F, Di Gennaro F, Salvatore M, Sodano A
* Scintimammography with Tc-99m-MIBI versus dynamic MRI for non-invasive characterization of breast masses (525 views)
Eur J Nucl Med (ISSN: 1619-7070, 1619-7089, 0340-6997), 2001 Jan; 28(1): 56-63.
Impact Factor: 3.464
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Fonti R, Del Vecchio S, Zannetti A, De Renzo A, Di Gennaro F, Catalano L, Califano C, Pace L, Rotoli B, Salvatore M
* Bone marrow uptake of 99mTc-MIBI in patients with multiple myeloma (428 views)
Eur J Nucl Med (ISSN: 0340-6997, 1619-7070, 1619-7089), 2001; 28(2): 214-220.
Impact Factor: 3.464
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Blocklet D, Schoutens A, Kentos A, Feremans W, Fonti R, Del Vecchio S, Pace L
* Bone marrow uptake of 99mTc-MIBI in patients with multiple myeloma [1] (multiple letters) (304 views)
Eur J Nucl Med (ISSN: 0340-6997, 1619-7070, 1619-7089), 2001; 28(9): 1430-1432.
Impact Factor: 3.464
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Del Vecchio S, Ciarmiello A, Salvatore M
Scintigraphic detection of multidrug resistance in cancer (457 views)
Cancer Biotherapy And Radiopharmaceuticals (ISSN: 1084-9785, 1084-4978), 2000 Sep; 15(4): 327-337.
Impact Factor: 0.989
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Fonti R, Del Vecchio S, Zannetti A, De Renzo A, Di Gennaro F, Catalano L, Califano C, Pace L, Rotoli B, Salvatore M
Bone marrow uptake of 99mTc-MIBI in patients with multiple myeloma (379 views)
Eur J Nucl Med (ISSN: 0340-6997, 1619-7070, 1619-7089), 1999 Sep; 26(9): N/D-N/D.
Impact Factor: 3.239
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Aloj L, Del Vecchio S, Damiano M, Zannetti A, Di Gennaro F, Imbriaco M, Salvatore M
Fractional retention of 99mTc-MIBI and proliferation in untreated breast cancer (332 views)
Eur J Nucl Med (ISSN: 0340-6997, 1619-7070, 1619-7089), 1999 Sep; 26(9): N/D-N/D.
Impact Factor: 3.239
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Del Vecchio S, Fonti R, Zannetti A, De Renzo A, Di Gennaro F, Catalano L, Califano C, Pace L, Rotoli B, Salvatore M
Functional imaging of multidrug resistant phenotype by 99mTc-MIBI scan in patients with multiple myeloma (354 views)
Eur J Nucl Med (ISSN: 0340-6997, 1619-7070, 1619-7089), 1999 Sep; 26(9): N/D-N/D.
Impact Factor: 3.239
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Del Vecchio S, Ciarmiello A, Salvatore M
Clinical imaging of multidrug resistance in cancer (360 views)
Q J Nucl Med (ISSN: 1124-3937, 1125-0135), 1999 Jun; 43(2): 125-131.
Impact Factor: 2.125
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Di Gennaro F, Catalano L, Pace L, de Renzo A, Pinto AM, del Vecchio S, Rotoli B, Salvatore M
Tc-99m sestamibi scintigraphy in multiple myeloma (271 views)
Clin Nucl Med (ISSN: 0363-9762, 1536-0229, 1536-0229electronic), 1999 Feb; 24(2): 115-116.
Impact Factor: 0.253
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Fonti R, Levchenko A, Mehta BM, Zhang J, Tsuruo T, Larson SM
Measurement of P-glycoprotein expression in human neuroblastoma xenografts using in vitro quantitative autoradiography (284 views)
Nucl Med Biol (ISSN: 0969-8051, 0883-2897), 1999 Jan; 26(1): 35-41.
Impact Factor: 1.623
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Catalano L, Pace L, Califano C, Pinto AM, De Renzo A, Di Gennaro F, Del Vecchio S, Fonti R, Salvatore M, Rotoli B
Detection of focal myeloma lesions by technetium-99m-sestaMIBI scintigraphy (358 views)
Haematologica (ISSN: 0390-6078, 0006-4971, 0006-6497), 1998 Nov 15; 92(10): 119-124.
Impact Factor: 1.876
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Pace L, Catalano L, Pinto A, De Renzo A, Di Gennaro F, Califano C, Del Vecchio S, Rotoli B, Salvatore M
Different patterns of technetium-99m sestamibi uptake in multiple myeloma (344 views)
Eur J Nucl Med (ISSN: 0340-6997, 1619-7070, 1619-7089), 1998 Jul; 25(7): 714-720.
Impact Factor: 2.564
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Salvatore M, Del Vecchio S
Dynamic imaging: Scintimammography (383 views)
Eur J Radiol Elsevier Sci Ireland Ltd (ISSN: 0720-048x), 1998 May; 27(SUPPL.2): S259-S259.
Impact Factor: 0.537
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Mansi L, Rambaldi PF, Cuccurullo V, Pecori B, Quarantelli M, Fallanca F, Del Vecchio E
Diagnostic and prognostic role of 99mTc-Tetrofosmin in breast cancer (295 views)
Q J Nucl Med (ISSN: 1124-3937, 1125-0135), 1997 Sep; 41(3): 239-250.
Impact Factor: 2.125
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Del Vecchio S, Ciarmiello A, Pace L, Potena MI, Carriero MV, Mainolfi C, Thomas R, D'Aiuto G, Tsuruo T, Salvatore M
Fractional retention of technetium-99m-sestamibi as an index of P- glycoprotein expression in untreated breast cancer patients (908 views)
J Nucl Med (ISSN: 0161-5505, 1535-5667, 1535-5667electronic), 1997 Sep; 38(9): 1348-1351.
Impact Factor: 3.491
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Iaffaioli RV, Facchini G, Tortoriello A, Scala S, Pacelli R, La Mura G, Pagliarulo C, Palmieri G, Caponigro F
Modulation of chemosensitivity by alpha interferon in multiple myeloma and non-Hodgkin's lymphoma (462 views)
J Exp Ther Oncol (ISSN: 1359-4117), 1996 Jul; 1(4): 226-230.
Impact Factor: 0
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Levchenko A, Mehta B, Spengler BA, Narkar A, Fonti R, Biedler JL, Tsuruo T, Larson SM
Measurement of P-glycoprotein expression in multidrug-resistant human neuroblastoma cell lines using self-competitive binding assay (283 views)
Anal Biochem (ISSN: 0003-2697, 1096-0309electronic, 0003-2697linking), 1996 May 1; 236(2): 338-343.
Impact Factor: 2.017
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Maurea S, Cuocolo A, Soricelli A, Castelli L, Nappi A, Trimarco B, Salvatore M
Technetium-99m MIBI SPECT to identify viable myocardium in patients with chronic coronary artery disease and left ventricular dysfunction (296 views)
Radiol Med (ISSN: 0033-8362, 1826-6983, 1826-6983electronic), 1996; 92(3): 289-296.
Impact Factor: 0.967
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Del Vecchio S, Ciarmiello A, Potena MI, Carriero MV, Mainolfi C, Botti G, Tsuruo T, Salvatore M
Quantitation of P-glycoprotein in sections of human breast carcinoma (298 views)
J Nucl Med (ISSN: 0161-5505, 1535-5667, 1535-5667electronic), 1995; 36(5SUPPL.): N/D-N/D.
Impact Factor: 3.491
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Ciarmiello A, Del Vecchio S, Potena MI, Mainolfi C, Carriero MV, Tsuruo T, Marone A, Salvatore M
Tc-99m-SESTAMIBI efflux and P-glycoprotein expression in human breast carcinoma (261 views)
J Nucl Med (ISSN: 0161-5505, 1535-5667, 1535-5667electronic), 1995; 36(5SUPPL.): N/D-N/D.
Impact Factor: 3.491
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Correale P, Caraglia M, Pepe S, Ricciardi B, Barile C, Montagnani S, Pacelli R, Bianco A, Tagliaferri P
PHORBOL 12-MYRISTATE 13-ACETATE (PMA) INDUCES NEUROENDOCRINE-LIKE DIFFERENTIATION AND REVERSES DOXORUBICIN-RESISTANCE OF HUMAN COLON-CARCINOMA CELLS IN-VITRO (299 views)
Int J Oncol (ISSN: 1019-6439, 1791-2423electronic, 1019-6439linking), 1994 Feb; 4(2): 423-427.
Impact Factor: 1.181
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* F-18 FDG PET/CT and F-18 FLT PET/CT as predictors of outcome in patients with multiple myeloma. A pilot study (25 views)
Eur J Radiol (ISSN: 0720-048xlinking), 2021 Mar; 136: 109564-109564.
Impact Factor: 3.528
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Fonti R, Pellegrino S, Catalano L, Pane F, Del Vecchio S, Pace L
* Visual and volumetric parameters by 18F-FDG-PET/CT: a head to head comparison for the prediction of outcome in patients with multiple myeloma (117 views)
Ann Hematol (ISSN: 0939-5555linking), 2020 Jan; 99(1): 127-135.
Impact Factor: 2.342
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Tornatore L, Capece D, D'Andrea D, Begalli F, Verzella D, Bennett J, Acton G, Campbell EA, Kelly J, Tarbit M, Adams N, Bannoo S, Leonardi A, Sandomenico A, Raimondo D, Ruvo M, Chambery A, Oblak M, Al-obaidi MJ, Kaczmarski RS, Gabriel I, Oakervee HE, Kaiser MF, Wechalekar A, Benjamin R, Apperley JF, Auner HW, Franzoso G
* Preclinical toxicology and safety pharmacology of the first-in-class GADD45beta/MKK7 inhibitor and clinical candidate, DTP3 (141 views)
Toxicol Rep (ISSN: 2214-7500linking), 2019 Apr 19; 6: 369-379.
Impact Factor: 1.161
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Tornatore L, Capece D, D'Andrea D, Begalli F, Verzella D, Bennett J, Acton G, Campbell EA, Kelly J, Tarbit M, Adams N, Bannoo S, Leonardi A, Sandomenico A, Raimondo D, Ruvo M, Chambery A, Oblak M, Al-obaidi MJ, Kaczmarski RS, Gabriel I, Oakervee HE, Kaiser MF, Wechalekar A, Benjamin R, Apperley JF, Auner HW, Franzoso G
* Clinical proof of concept for a safe and effective NF-kappaB-targeting strategy in multiple myeloma (236 views)
Br J Haematol (ISSN: 1365-2141electronic, 0007-1048linking), 2018 Sep 26; N/D: N/D-N/D.
Impact Factor: 4.498
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Fonti R, Pace L, Cerchione C, Catalano L, Salvatore B, Pane F, Salvatore M, Del Vecchio S
* 18F-FDG PET/CT, 99mTc-MIBI, and MRI in the prediction of outcome of patients with multiple myeloma: a comparative study (432 views) (PDF 255 views)
Clin Nucl Med (ISSN: 0363-9762, 1536-0229, 1536-0229electronic), 2015 Apr; 40(4): 303-308.
Impact Factor: 4.278
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Fonti R, Pace L, Cerchione C, Catalano L, Pane F, Salvatore M, Del Vecchio S
* 18F-FDG-PET/CT, 99mTc-MIBI and MRI in the Prediction of Outcome of Patients with Multiple Myeloma (310 views)
Eur J Nucl Med (ISSN: 1619-7070, 1619-7089, 1619-7070print), 2015 Jan 20; 40: 303-308.
Impact Factor: 5.537
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Berisio R
* Editorial: Molecular determinants of bacterial diseases (354 views)
Curr Med Chem (ISSN: 0929-8673, 1875-533x, 1875-533xelectronic), 2015; 22(14): 1640-1641.
Impact Factor: 3.455
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Tornatore L, Sandomenico A, Raimondo D, Low C, Rocci A, Tralau-Stewart C, Capece D, D'Andrea D, Bua M, Boyle E, van Duin M, Zoppoli P, Jaxa-Chamiec A, Thotakura AK, Dyson J, Walker BA, Leonardi A, Chambery A, Driessen C, Sonneveld P, Morgan G, Palumbo A, Tramontano A, Rahemtulla A, Ruvo M, Franzoso G
* Cancer-selective targeting of the NF-kappaB survival pathway with GADD45beta/MKK7 inhibitors (622 views)
Cancer Cell (ISSN: 1535-6108), 2014 Oct 13; 26(4): 495-508.
Impact Factor: 23.523
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Camera L, Sagnelli M, Guadagno P, Mainenti PP, Marra T, Scotto di Santolo M, Fei L, Salvatore M
* Colonic perforation by a transmural and transvalvular migrated retained sponge: Multi-detector computed tomography findings (358 views)
World J Gastroentero (ISSN: 1007-9327, 2219-2840, 1007-9327linking), 2014 Apr 21; 20(15): 4457-4461.
Impact Factor: 2.369
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Camera L, Calabrese M, Romeo V, Scordino F, Mainenti PP, Clemente M, Rapicano G, Salvatore M
* Perforated duodenal ulcer presenting with a subphrenic abscess revealed by plain abdominal X-ray films and confirmed by multi-detector computed tomography: A case report (333 views)
J Med Case Rep (ISSN: 1752-1947, 1752-1947linking), 2013 Nov 11; 7: 257-257.
Impact Factor: 0.895
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Bartolucci S, Contursi P, Fiorentino G, Limauro D, Pedone E
* Responding to toxic compounds: a genomic and functional overview of Archaea (693 views)
Frontiers In Bioscience (ISSN: 1093-9946, 1093-4715), 2013 Jan 1; 18: 165-189.
Impact Factor: 4.249
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Fonti R, Larobina M, Del Vecchio S, Fabbricini R, Catalano L, Pane F, Salvatore M, Pace L
* Metabolic tumor volume assessed by 18F-FDG PET/CT for the prediction of outcome in patients with multiple myeloma (546 views)
J Nucl Med (ISSN: 1535-5667, 0161-5505, 1535-5667electronic), 2012 Dec; 53(12): 1829-1835.
Impact Factor: 5.774
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Mainenti PP
* Imaging features of small bowel amyloidosis at PET/CT (237 views)
Abdom Imaging (ISSN: 0942-8925, 1432-0509), 2012 Oct; 37(5): 911-911.
Impact Factor: 1.905
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Pier PM
* RE: Imaging Features of Hepato-Splenic Amyloidosis at PET/CT (293 views)
Korean Journal Of Radiology (ISSN: 1229-6929), 2012 May; 13(3): 368-369.
Impact Factor: 1.555
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Fonti R, Larobina M, Fabbricini R, Catalano L, Pace L, Del Vecchio S, Salvatore M
* Metabolic Tumor Volume assessed by 18F-FDG-PET/CT in the evaluation of plasma cell mass and prediction of outcome in patients with multiple myeloma (312 views)
Eur J Nucl Med (ISSN: 1619-7070, 1619-7089, 0340-6997), 2010 Oct; 37: N/D-N/D.
Impact Factor: 5.036
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Di Fiore A, Fiorentino G, Vitale RM, Ronca R, Amodeo P, Pedone C, Bartolucci S, De Simone G
* Structural analysis of BldR from Sulfolobus solfataricus provides insights into the molecular basis of transcriptional activation in Archaea by MarR family proteins (470 views)
J Mol Biol (ISSN: 1089-8638, 0022-2836, 1089-8638electronic), 2009 May 8; 388(3): 559-569.
Impact Factor: 3.871
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Del Vecchio S, Zannetti A, Fonti R, Iommelli F, Lettieri A, Salvatore M
* Molecular imaging of drug resistance in cancer (436 views)
Minerva Biotecnol (ISSN: 1120-4826), 2009 Mar; 21(1): 31-36.
Impact Factor: 0.268
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Fonti R, Salvatore B, Quarantelli M, Sirignano C, Segreto S, Petruzziello F, Catalano L, Liuzzi R, Rotoli B, Del Vecchio S, Pace L, Salvatore M
* F-18-FDG PET/CT, Tc-99m-MIBI, and MRI in evaluation of patients with multiple myeloma (544 views)
J Nucl Med (ISSN: 0161-5505, 0161-1550, 1535-5667), 2008 Feb; 49(2): 195-200.
Impact Factor: 6.662
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Fonti R, Salvatore B, Ricci F, Petruzziello F, Catalano L, Rotoli B, Del Vecchio S, Pace L, Salvatore M
* 18F-FDG-PET/CT in the evaluation of bone marrow infiltration in patients with multiple myeloma (288 views)
Eur J Nucl Med (ISSN: 1619-7070, 1619-7089, 0340-6997), 2007 Oct; 34: N/D-N/D.
Impact Factor: 4.101
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Fonti R, Salvatore B, Ricci F, Petruzziello F, Catalano L, Del Vecchio S, Pace L, Salvatore M, Rotoli B
* F-18-FDG-PET/CT in the evaluation of bone marrow infiltration in patients with multiple myeloma (235 views)
Haematologica (ISSN: 0390-6078, 0006-4971, 0006-6497), 2007 Oct; 92: N/D-N/D.
Impact Factor: 5.516
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Fonti R, Salvatore B, Ricci F, Petruzziello F, Catalano L, Del Vecchio S, Pace L, Salvatore M, Rotoli B
* F-18-FDG-PET/CT, 99mTC-MIBI and MRI in the evaluation of patients with multiple myeloma (350 views)
Haematologica (ISSN: 0390-6078, 0006-4971, 0006-6497), 2007 Oct; 92: N/D-N/D.
Impact Factor: 5.516
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Del Vecchio S, Zannetti A, Fonti R, Pace L, Salvatore M
* Nuclear imaging in cancer theranostics (615 views)
Q J Nucl Med Mol Im (ISSN: 1824-4785, 1824-4478, 1824-4785linking), 2007 Jun; 51(2): 152-163.
Impact Factor: 1.724
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Catalano L, Del Vecchio S, Petruzziello F, Fonti R, Salvatore B, Martorelli C, Califano C, Caparrotti G, Segreto S, Pace L, Rotoli B
* Sestamibi and FDG-PET scans to support diagnosis of jaw osteonecrosis (407 views)
Ann Hematol (ISSN: 0939-5555, 0939-5555linking), 2007 Jun; 86(6): 415-423.
Impact Factor: 2.342
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Fonti R, Salvatore B, Quarantelli M, Sirignano C, Segreto S, Petruzziello F, Catalano L, Rotoli B, Del Vecchio S, Pace L, Salvatore M
* Multimodality Imaging With 18f-Fdg-Pet/Ct, 99mtc-Mibi And Mri Of Multiple Myeloma (321 views)
Proceedings Of The 2nd International Conference Of The European Society For Molecular Imaging Naples Italy, 2007; N/D: 56-56.
Impact Factor: 0
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Fonti R, Salvatore B, Quarantelli M, Sirignano C, Cammarano F, Segreto S, Petruzziello F, Catalano L, Rotoli B, Del Vecchio S, Pace L, Salvatore M
* 18F-FDG-PET/CT, 99mTc-MIBI and MRI in the evaluation of patients with multiple myeloma (397 views)
Eur J Nucl Med (ISSN: 1619-7070, 1619-7089, 0340-6997), 2006 Sep; 33: N/D-N/D.
Impact Factor: 4.041
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Del Vecchio S, Zannetti A, Iommelli F, Papaccioli A, Sommella J, Ferraro P, Baiano A, Salvatore M
* In vivo detection of early tumor response to tyrosine kinase inhibitors by microSPECT with 99mTc-MIBI (403 views)
Eur J Nucl Med (ISSN: 1619-7070, 1619-7089, 0340-6997), 2006 Sep; 33: N/D-N/D.
Impact Factor: 4.041
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Pace L, Salvatore M, Del Vecchio S
* Use of Tc-99m-Sestamibi scintigraphy in multiple myeloma (241 views)
J Nucl Med (ISSN: 1535-5667, 0161-5505, 1535-5667electronic), 2006 Mar; 47(3): 555-555.
Impact Factor: 4.986
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Fonti R, Salvatore B, Quarantelli M, Sirignano C, Cammarano F, Segreto S, Petruzziello F, Catalano L, Martinelli V, Rotoli B, Del Vecchio S, Pace L, Salvatore M
* 18f-Fdg-Pet/Ct, 99mtc-Mibi And Mri Inpatients With Multiple Myeloma (352 views)
Multimodality Imaging With Proceedings Of The Ix Congress Of The Italian Society Of Experimental Hematology, 2006; PO164: 53-53.
Impact Factor: 0
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Del Vecchio S, Zannetti A, Salvatore B, Paone G, Fonti R, Salvatore M
* Functional imaging of multidrug resistance in breast cancer (408 views)
Phys Med (ISSN: 1120-1797, 1120-1797linking), 2006; 21(SUPPL.1): 24-27.
Impact Factor: 0.313
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Del Vecchio S, Zannetti A, Fonti R, Iommelli F, Sommella I, Potena A, Salvatore M
* 99mTc-MIBI uptake in Bcl-2 overexpressing breast cancer cells during treatment with gefitinib, a selective tyrosine kinase inhibitor (380 views)
Eur J Nucl Med (ISSN: 1619-7070, 1619-7089, 0340-6997), 2005 Sep; 32: N/D-N/D.
Impact Factor: 3.883
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Catalano L, Andretta C, Pace L, Del Vecchio S, Salvatore B, De Rosa G, Buonanno MT, Paone G, Rotoli B
* Tc 99-Sesta Mibi Uptake In Nonsecretory Multiple Myeloma (354 views)
Hematology (ISSN: 1024-5332), 2005 Sep; 10(4): 335-338.
Impact Factor: 1.189
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Pace L, Catalano L, Del Vecchio S, De Renzo A, Fonti R, Salvatore B, Andretta C, Di Nuzzo C, Rotoli B, Salvatore M
* Washout of [99mTc] sestamibi in predicting response to chemotherapy in patients with multiple myeloma (381 views)
Q J Nucl Med Mol Im (ISSN: 1824-4785, 1824-4478, 1824-4785linking), 2005 Sep; 49(3): 281-285.
Impact Factor: 1.724
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Pace L, Del Vecchio S, Salvatore M
* Technetium 99m sestamibi in multiple myeloma (272 views)
Radiology (ISSN: 0033-8419, 1527-1315, 1527-1315electronic), 2005 Jan; 234(1): 312-313.
Impact Factor: 5.377
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Zannetti A, Del Vecchio S, Fonti R, Iommelli F, Sommella J, Potena A, Salvatore M
* Gefitinib, A Selective, Tyrosine Kinase Inhibitor Increases 99mtc-Mibi Uptake In Bcl-2 Overexpressing Breast Cancer Cells (380 views)
Mol Immunol, 2005; 4: 355-355.
Impact Factor: 3.003
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Pace L, Del Vecchio S, Salvatore M, Walker RC, Angtuaco E, Sethi R, Fassas A, Barlogie B
* Technetium 99m sestamibi in multiple myeloma [3] (multiple letters) (339 views)
Radiology (ISSN: 0033-8419, 1527-1315, 1527-1315electronic), 2005; 234(1): 312-313.
Impact Factor: 5.377
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Del Vecchio S, Zannetti A, Salvatore B, Paone G, Fonti R, Iommelli F, De Renzo A, Rotoli B, Salvatore M
* 99mTc-MIBI uptake in Bcl-2 overexpressing non-Hodgkin's lymphoma patients during drug-induced apoptosis (353 views)
Eur J Nucl Med (ISSN: 1619-7070, 1619-7089, 0340-6997), 2004 Sep; 31: N/D-N/D.
Impact Factor: 3.935
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Del Vecchio S, Salvatore M
* Tc-99m-MIBI in the evaluation of breast cancer biology (598 views) (PDF 182 views)
Eur J Nucl Med (ISSN: 1619-7070, 1619-7089, 0340-6997), 2004 Jun; 31(SUPPL.1): S88-S88.
Impact Factor: 3.935
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Aloj L, Zannetti A, Caracó C, Del Vecchio S, Salvatore M
* Bcl-2 overexpression prevents 99mTc-MIBI uptake in breast cancer cell lines (555 views)
Eur J Nucl Med (ISSN: 1619-7070, 1619-7089, 0340-6997), 2004; 31(4): 521-527.
Impact Factor: 3.935
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Pace L, Salvatore M, Del Vecchio S
* A new role for nuclear medicine in multiple Myeloma (321 views)
J Nucl Med (ISSN: 0161-5505, 1535-5667, 1535-5667electronic), 2003 Sep; 44(8): 1369-1369.
Impact Factor: 4.899
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Andretta C, Catalano L, Pace L, Fonti R, Annunziata G, Rotoli B
* 99mTc-sestaMIBI scintigraphy in thalidomide-treated refractory or relapsed multiple myeloma patients [2] (290 views)
Leuk Lymphoma (ISSN: 1042-8194, 1026-8022linking), 2003 Jun; 44(6): 1081-1082.
Impact Factor: 1.163
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Del Vecchio S, Zannetti A, Aloj L, Caracò C, Ciarmiello A, Salvatore M
* Inhibition of early Tc-99m-MIBI uptake by Bcl-2 anti-apoptotic protein overexpression in untreated breast carcinoma (524 views)
Eur J Nucl Med (ISSN: 1619-7070, 1619-7089, 0340-6997), 2003 Jun; 30(6): 879-887.
Impact Factor: 3.324
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Del Vecchio S, Zannetti A, Aloj L, Salvatore M
* MIBI as prognostic factor in breast cancer (459 views)
Q J Nucl Med (ISSN: 1124-3937, 1125-0135), 2003 Mar; 47(1): 46-50.
Impact Factor: 2.222
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Del Vecchio S, Zannetti A, Ciarmiello A, Aloj L, Caracò C, Fonti R, Botti G, D'Aiuto G, Salvatore M
* Dynamic coupling of Tc-99m-MIBI efflux and apoptotic pathway activation in untreated breast cancer patients (481 views)
Eur J Nucl Med (ISSN: 1619-7070, 0340-6997, 1619-7089), 2002 Jun; 29(6): 809-814.
Impact Factor: 3.568
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Marino M, Rossi M, Ruvo M, Fassina G
* Novel molecular targets for systemic lupus erythematosus (369 views)
Curr Drug Targets (ISSN: 1389-4501), 2002 Jun; 3(3): 223-228.
Impact Factor: 3.597
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Del Vecchio S, Zannetti A, Ciarmiello A, Aloj L, Fonti R, Caraco C, Salvatore M
* 99mTc-MIBI uptake and Bcl-2 overexpression in untreated breast cancer patients (368 views)
Eur J Nucl Med (ISSN: 0340-6997, 1619-7070, 1619-7089), 2001 Sep; 28(8): N/D-N/D.
Impact Factor: 3.464
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Aloj L, Zannetti A, Caraco C, Fonti R, Del Vecchio S, Salvatore M
* 99mTc-MIBI uptake in breast cancer cells during early phases of apoptosis induction with Staurosporine (370 views)
Eur J Nucl Med (ISSN: 0340-6997, 1619-7070, 1619-7089), 2001 Sep; 28(8): N/D-N/D.
Impact Factor: 3.464
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Aloj L, Del Vecchio S, Zannetti A, Caracò C, Salvatore M
* 99mTc-MIBI uptake is reduced in Bcl-2 overexpressing MCF-7 breast cancer cells (357 views)
Eur J Nucl Med (ISSN: 0340-6997, 1619-7070, 1619-7089), 2001 Sep; 28(8): N/D-N/D.
Impact Factor: 3.464
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Pace L, Catalano L, Del Vecchio S, De Renzo A, Fonti R, Sica G, Annunziata G, Califano C, Rotoli B, Salvatore M
* Wash-out of 99mTc-sestamibi (99mTc-MIBI) in evaluating response to chemotherapy in patients with multiple myeloma (MM) (305 views)
Eur J Nucl Med (ISSN: 0340-6997, 1619-7070, 1619-7089), 2001 Sep; 28(8): N/D-N/D.
Impact Factor: 3.464
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Pace L, Catalano L, Del Vecchio S, Di Gennaro F, De Renzo A, Sica G, Califano C, Tedesco N, Borrelli G, Rotoli B, Salvatore M
* Predictive value of technetium-99m sestamibi in patients with multiple myeloma and potential role in the follow-up (410 views)
Eur J Nucl Med (ISSN: 0340-6997, 1619-7070, 1619-7089), 2001 Mar; 28(3): 304-312.
Impact Factor: 3.464
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Imbriaco M, Del Vecchio S, Riccardi A, Pace L, Di Salle F, Di Gennaro F, Salvatore M, Sodano A
* Scintimammography with Tc-99m-MIBI versus dynamic MRI for non-invasive characterization of breast masses (525 views)
Eur J Nucl Med (ISSN: 1619-7070, 1619-7089, 0340-6997), 2001 Jan; 28(1): 56-63.
Impact Factor: 3.464
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Fonti R, Del Vecchio S, Zannetti A, De Renzo A, Di Gennaro F, Catalano L, Califano C, Pace L, Rotoli B, Salvatore M
* Bone marrow uptake of 99mTc-MIBI in patients with multiple myeloma (428 views)
Eur J Nucl Med (ISSN: 0340-6997, 1619-7070, 1619-7089), 2001; 28(2): 214-220.
Impact Factor: 3.464
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Blocklet D, Schoutens A, Kentos A, Feremans W, Fonti R, Del Vecchio S, Pace L
* Bone marrow uptake of 99mTc-MIBI in patients with multiple myeloma [1] (multiple letters) (304 views)
Eur J Nucl Med (ISSN: 0340-6997, 1619-7070, 1619-7089), 2001; 28(9): 1430-1432.
Impact Factor: 3.464
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Del Vecchio S, Ciarmiello A, Salvatore M
Scintigraphic detection of multidrug resistance in cancer (457 views)
Cancer Biotherapy And Radiopharmaceuticals (ISSN: 1084-9785, 1084-4978), 2000 Sep; 15(4): 327-337.
Impact Factor: 0.989
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Fonti R, Del Vecchio S, Zannetti A, De Renzo A, Di Gennaro F, Catalano L, Califano C, Pace L, Rotoli B, Salvatore M
Bone marrow uptake of 99mTc-MIBI in patients with multiple myeloma (379 views)
Eur J Nucl Med (ISSN: 0340-6997, 1619-7070, 1619-7089), 1999 Sep; 26(9): N/D-N/D.
Impact Factor: 3.239
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Aloj L, Del Vecchio S, Damiano M, Zannetti A, Di Gennaro F, Imbriaco M, Salvatore M
Fractional retention of 99mTc-MIBI and proliferation in untreated breast cancer (332 views)
Eur J Nucl Med (ISSN: 0340-6997, 1619-7070, 1619-7089), 1999 Sep; 26(9): N/D-N/D.
Impact Factor: 3.239
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Del Vecchio S, Fonti R, Zannetti A, De Renzo A, Di Gennaro F, Catalano L, Califano C, Pace L, Rotoli B, Salvatore M
Functional imaging of multidrug resistant phenotype by 99mTc-MIBI scan in patients with multiple myeloma (354 views)
Eur J Nucl Med (ISSN: 0340-6997, 1619-7070, 1619-7089), 1999 Sep; 26(9): N/D-N/D.
Impact Factor: 3.239
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Del Vecchio S, Ciarmiello A, Salvatore M
Clinical imaging of multidrug resistance in cancer (360 views)
Q J Nucl Med (ISSN: 1124-3937, 1125-0135), 1999 Jun; 43(2): 125-131.
Impact Factor: 2.125
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Di Gennaro F, Catalano L, Pace L, de Renzo A, Pinto AM, del Vecchio S, Rotoli B, Salvatore M
Tc-99m sestamibi scintigraphy in multiple myeloma (271 views)
Clin Nucl Med (ISSN: 0363-9762, 1536-0229, 1536-0229electronic), 1999 Feb; 24(2): 115-116.
Impact Factor: 0.253
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Fonti R, Levchenko A, Mehta BM, Zhang J, Tsuruo T, Larson SM
Measurement of P-glycoprotein expression in human neuroblastoma xenografts using in vitro quantitative autoradiography (284 views)
Nucl Med Biol (ISSN: 0969-8051, 0883-2897), 1999 Jan; 26(1): 35-41.
Impact Factor: 1.623
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Catalano L, Pace L, Califano C, Pinto AM, De Renzo A, Di Gennaro F, Del Vecchio S, Fonti R, Salvatore M, Rotoli B
Detection of focal myeloma lesions by technetium-99m-sestaMIBI scintigraphy (358 views)
Haematologica (ISSN: 0390-6078, 0006-4971, 0006-6497), 1998 Nov 15; 92(10): 119-124.
Impact Factor: 1.876
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Pace L, Catalano L, Pinto A, De Renzo A, Di Gennaro F, Califano C, Del Vecchio S, Rotoli B, Salvatore M
Different patterns of technetium-99m sestamibi uptake in multiple myeloma (344 views)
Eur J Nucl Med (ISSN: 0340-6997, 1619-7070, 1619-7089), 1998 Jul; 25(7): 714-720.
Impact Factor: 2.564
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Salvatore M, Del Vecchio S
Dynamic imaging: Scintimammography (383 views)
Eur J Radiol Elsevier Sci Ireland Ltd (ISSN: 0720-048x), 1998 May; 27(SUPPL.2): S259-S259.
Impact Factor: 0.537
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Mansi L, Rambaldi PF, Cuccurullo V, Pecori B, Quarantelli M, Fallanca F, Del Vecchio E
Diagnostic and prognostic role of 99mTc-Tetrofosmin in breast cancer (295 views)
Q J Nucl Med (ISSN: 1124-3937, 1125-0135), 1997 Sep; 41(3): 239-250.
Impact Factor: 2.125
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Del Vecchio S, Ciarmiello A, Pace L, Potena MI, Carriero MV, Mainolfi C, Thomas R, D'Aiuto G, Tsuruo T, Salvatore M
Fractional retention of technetium-99m-sestamibi as an index of P- glycoprotein expression in untreated breast cancer patients (908 views)
J Nucl Med (ISSN: 0161-5505, 1535-5667, 1535-5667electronic), 1997 Sep; 38(9): 1348-1351.
Impact Factor: 3.491
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Iaffaioli RV, Facchini G, Tortoriello A, Scala S, Pacelli R, La Mura G, Pagliarulo C, Palmieri G, Caponigro F
Modulation of chemosensitivity by alpha interferon in multiple myeloma and non-Hodgkin's lymphoma (462 views)
J Exp Ther Oncol (ISSN: 1359-4117), 1996 Jul; 1(4): 226-230.
Impact Factor: 0
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Levchenko A, Mehta B, Spengler BA, Narkar A, Fonti R, Biedler JL, Tsuruo T, Larson SM
Measurement of P-glycoprotein expression in multidrug-resistant human neuroblastoma cell lines using self-competitive binding assay (283 views)
Anal Biochem (ISSN: 0003-2697, 1096-0309electronic, 0003-2697linking), 1996 May 1; 236(2): 338-343.
Impact Factor: 2.017
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Maurea S, Cuocolo A, Soricelli A, Castelli L, Nappi A, Trimarco B, Salvatore M
Technetium-99m MIBI SPECT to identify viable myocardium in patients with chronic coronary artery disease and left ventricular dysfunction (296 views)
Radiol Med (ISSN: 0033-8362, 1826-6983, 1826-6983electronic), 1996; 92(3): 289-296.
Impact Factor: 0.967
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Del Vecchio S, Ciarmiello A, Potena MI, Carriero MV, Mainolfi C, Botti G, Tsuruo T, Salvatore M
Quantitation of P-glycoprotein in sections of human breast carcinoma (298 views)
J Nucl Med (ISSN: 0161-5505, 1535-5667, 1535-5667electronic), 1995; 36(5SUPPL.): N/D-N/D.
Impact Factor: 3.491
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Ciarmiello A, Del Vecchio S, Potena MI, Mainolfi C, Carriero MV, Tsuruo T, Marone A, Salvatore M
Tc-99m-SESTAMIBI efflux and P-glycoprotein expression in human breast carcinoma (261 views)
J Nucl Med (ISSN: 0161-5505, 1535-5667, 1535-5667electronic), 1995; 36(5SUPPL.): N/D-N/D.
Impact Factor: 3.491
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Correale P, Caraglia M, Pepe S, Ricciardi B, Barile C, Montagnani S, Pacelli R, Bianco A, Tagliaferri P
PHORBOL 12-MYRISTATE 13-ACETATE (PMA) INDUCES NEUROENDOCRINE-LIKE DIFFERENTIATION AND REVERSES DOXORUBICIN-RESISTANCE OF HUMAN COLON-CARCINOMA CELLS IN-VITRO (299 views)
Int J Oncol (ISSN: 1019-6439, 1791-2423electronic, 1019-6439linking), 1994 Feb; 4(2): 423-427.
Impact Factor: 1.181
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70 Records (42 excluding Abstracts).
Total impact factor: 228.776 (134.342 excluding Abstracts).
Total 5 year impact factor: 271.301 (156.426 excluding Abstracts).
Total impact factor: 228.776 (134.342 excluding Abstracts).
Total 5 year impact factor: 271.301 (156.426 excluding Abstracts).
461 views. Last view on Friday 27 January 2023, 16:39:11
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