Institute of Biostructures and Bioimaging-National Research Council (CNR), Via Mezzocannone 16, I-80134 Naples, Italy. vincenzo.alterio@cnr.it., Institute of Biostructures and Bioimaging-National Research Council (CNR), Via Mezzocannone 16, I-80134 Naples, Italy. emma.langella@cnr.it., Institute of Biostructures and Bioimaging-National Research Council (CNR), Via Mezzocannone 16, I-80134 Naples, Italy. gdesimon@unina.it., Institute of Biostructures and Bioimaging-National Research Council (CNR), Via Mezzocannone 16, I-80134 Naples, Italy. marmonti@unina.it.,
References: Lane, T.W., Morel, F.M., A biological function for cadmium in marine diatoms (2000) Proc. Natl. Acad. Sci. USA, 97, pp. 4627-463
Boyle, E.A., Sclater, F., Edmond, J.M., Marine geochemistry of cadmium (1976) Nat. Chem. Biol., 263, p. 3
Xu, Y., Feng, L., Jeffrey, P.D., Shi, Y., Morel, F.M., Structure and metal exchange in the cadmium carbonic anhydrase of marine diatoms (2008) Nature, 452, pp. 56-61
Falkowski, P.G., Katz, M.E., Knoll, A.H., Quigg, A., Raven, J.A., Schofield, O., Taylor, F.J., The evolution of modern eukaryotic phytoplankton (2004) Science, 305, pp. 354-360
Krishnamurthy, V.M., Kaufman, G.K., Urbach, A.R., Gitlin, I., Gudiksen, K.L., Weibel, D.B., Whitesides, G.M., Carbonic anhydrase as a model for biophysical and physical-organic studies of proteins and protein-ligand binding (2008) Chem. Rev., 108, pp. 946-1051
Supuran, C.T., Carbonic anhydrases: Novel therapeutic applications for inhibitors and activators (2008) Nat. Rev. Drug Discov., 7, pp. 168-181
Supuran, C.T., Winum, J.-Y., (2009) Drug Design of Zinc-Enzyme Inhibitors: Functional, Structural, and Disease Applications, 10. , Wiley: Hoboken, NJ, USA
Maren, T.H., Carbonic anhydrase: Chemistry, physiology, and inhibition (1967) Physiol. Rev., 47, pp. 595-781
Beauchemin, M., Morse, D., Delta carbonic anhydrases: Structure, distribution and potential roles (2015) Carbonic Anhydrases as Biocatalysts from Theory to Medical and Industrial Applications, pp. 337-349. , Supuran, C.T., De Simone, G., Eds. Elsevier: Amsterdam, The Netherlands
Xu, Y., Morel, F.M., Cadmium in marine phytoplankton (2013) Met. Ions Life Sci., 11, pp. 509-528
Chmielowska-Bak, J., Izbianska, K., Deckert, J., The toxic doppelganger: On the ionic and molecular mimicry of cadmium (2013) Acta Biochim. Pol., 60, pp. 369-374
Belyaeva, E.A., Dymkowska, D., Wieckowski, M.R., Wojtczak, L., Mitochondria as an important target in heavy metal toxicity in rat hepatoma as-30d cells (2008) Toxicol. Appl. Pharmacol., 231, pp. 34-42
Goncalves, J.F., Antes, F.G., Maldaner, J., Pereira, L.B., Tabaldi, L.A., Rauber, R., Rossato, L.V., Flores, E.M., Cadmium and mineral nutrient accumulation in potato plantlets grown under cadmium stress in two different experimental culture conditions (2009) Plant Physiol. Biochem., 47, pp. 814-821
Kippler, M., Hoque, A.M., Raqib, R., Ohrvik, H., Ekstrom, E.C., Vahter, M., Accumulation of cadmium in human placenta interacts with the transport of micronutrients to the fetus (2010) Toxicol. Lett., 192, pp. 162-168
Matovic, V., Buha, A., Bulat, Z., Dukic-Cosic, D., Cadmium toxicity revisited: Focus on oxidative stress induction and interactions with zinc and magnesium (2011) Arh. Hig. Rada Toksikol., 62, pp. 65-76
Pytharopoulou, S., Grintzalis, K., Sazakli, E., Leotsinidis, M., Georgiou, C.D., Kalpaxis, D.L., Translational responses and oxidative stress of mussels experimentally exposed to hg, cu and cd: One pattern does not fit at all (2011) Aquat. Toxicol., 105, pp. 157-165
Wang, L., Wang, H., Li, J., Chen, D., Liu, Z., Simultaneous effects of lead and cadmium on primary cultures of rat proximal tubular cells: Interaction of apoptosis and oxidative stress (2011) Arch. Environ. Contam. Toxicol., 61, pp. 500-511
Arasimowicz-Jelonek, M., Floryszak-Wieczorek, J., Deckert, J., Rucinska-Sobkowiak, R., Gzyl, J., Pawlak-Sprada, S., Abramowski, D., Gwozdz, E.A., Nitric oxide implication in cadmium-induced programmed cell death in roots and signaling response of yellow lupine plants (2012) Plant Physiol. Biochem., 58, pp. 124-134
Filipic, M., Mechanisms of cadmium induced genomic instability (2012) Mutat. Res., 733, pp. 69-77
Lane, T.W., Saito, M.A., George, G.N., Pickering, I.J., Prince, R.C., Morel, F.M., Biochemistry: A cadmium enzyme from a marine diatom (2005) Nature, 435, p. 42
Park, H., Song, B., Morel, F.M., Diversity of the cadmium-containing carbonic anhydrase in marine diatoms and natural waters (2007) Environ. Microbiol., 9, pp. 403-413
Viparelli, F., Monti, S.M., De Simone, G., Innocenti, A., Scozzafava, A., Xu, Y., Morel, F.M., Supuran, C.T., Inhibition of the r1 fragment of the cadmium-containing zeta-class carbonic anhydrase from the diatom thalassiosira weissflogii with anions (2010) Bioorganic Med. Chem. Lett., 20, pp. 4745-4748
Xu, Y., Supuran, C.T., Morel, F.M.M., Cadmium-Carbonic Anhydrase (2011) Encyclopedia of Inorganic and Bioinorganic Chemistry, , Scott, R.A., Ed. John Wiley and Sons, Ltd.: Hoboken, NJ, USA
Alterio, V., Langella, E., Viparelli, F., Vullo, D., Ascione, G., Dathan, N.A., Morel, F.M., Monti, S.M., Structural and inhibition insights into carbonic anhydrase cdca1 from the marine diatom thalassiosira weissflogii (2012) Biochimie, 94, pp. 1232-1241
Rosati, A.M., Traversa, U., Mechanisms of inhibitory effects of zinc and cadmium ions on agonist binding to adenosine a1 receptors in rat brain (1999) Biochem. Pharmacol., 58, pp. 623-632
Singh, R., Gautam, N., Mishra, A., Gupta, R., Heavy metals and living systems: An overview (2011) Indian J. Pharmacol., 43, pp. 246-253
Wang, J., Pantopoulos, K., Regulation of cellular iron metabolism (2011) Biochem. J., 434, pp. 365-381
Simonsen, L.O., Harbak, H., Bennekou, P., Cobalt metabolism and toxicology-A brief update (2012) Sci. Total Environ., 432, pp. 210-215
Arredondo, M., Nunez, M.T., Iron and copper metabolism (2005) Mol. Asp. Med., 26, pp. 313-327
Luevano, J., Damodaran, C., A review of molecular events of cadmium-induced carcinogenesis (2014) J. Environ. Pathol. Toxicol. Oncol., 33, pp. 183-194
Jarup, L., Hazards of heavy metal contamination (2003) Br. Med. Bull., 68, pp. 167-182
Lim, S.R., Schoenung, J.M., Human health and ecological toxicity potentials due to heavy metal content in waste electronic devices with flat panel displays (2010) J. Hazard. Mater., 177, pp. 251-259
Thompson, R.B., Maliwal, B.P., Feliccia, V.L., Fierke, C.A., McCall, K., Determination of picomolar concentrations of metal ions using fluorescence anisotropy: Biosensing with a "reagentless" enzyme transducer (1998) Anal. Chem., 70, pp. 4717-4723
Zeng, H.H., Thompson, R.B., Maliwal, B.P., Fones, G.R., Moffett, J.W., Fierke, C.A., Real-time determination of picomolar free cu(ii) in seawater using a fluorescence-based fiber optic biosensor (2003) Anal. Chem., 75, pp. 6807-6812
Hunt, J.A., Lesburg, C.A., Christianson, D.W., Thompson, R.B., Fierke, C.A., Active-site engineering of carbonic anhydrase and its application to biosensors (2000) The Carbonic Anhydrases: New Horizons, 90, pp. 221-240. , Chegwidden, W.R., Carter, N.D., Edwards, Y.H., Eds. Springer, Birkhäuser Verlag: Basel, Switzerland
Boone, C.D., Habibzadegan, A., Gill, S., McKenna, R., Carbonic anhydrases and their biotechnological applications (2013) Biomolecules, 3, pp. 553-562
Hurst, T.K., Wang, D., Thompson, R.B., Fierke, C.A., Carbonic anhydrase ii-based metal ion sensing: Advances and new perspectives (2010) Biochim. Biophys. Acta, 1804, pp. 393-403
Thakur, M.S., Ragavan, K.V., Biosensors in food processing (2013) J. Food Sci. Technol., 50, pp. 625-641
Kumar, H., Rani, R., Development of biosensors for the detection of biological warfare agents: Its issues and challenges (2013) Sci. Prog., 96, pp. 294-308
Bozym, R., Hurst, T.K., Westerberg, N., Stoddard, A., Fierke, C.A., Frederickson, C.J., Thompson, R.B., Determination of zinc using carbonic anhydrase-based fluorescence biosensors (2008) Methods Enzymol., 450, pp. 287-309
Fierke, C.A., Thompson, R.B., Fluorescence-based biosensing of zinc using carbonic anhydrase (2001) Biometals, 14, pp. 205-222
Lindskog, S., Nyman, P.O., Metal-binding properties of human erythrocyte carbonic anhydrases (1964) Biochim. Biophys. Acta, 85, pp. 462-474
Chen, R.F., Kernohan, J.C., Combination of bovine carbonic anhydrase with a fluorescent sulfonamide (1967) J. Biol. Chem., 242, pp. 5813-5823
Nair, S.K., Elbaum, D., Christianson, D.W., Unexpected binding mode of the sulfonamide fluorophore 5-dimethylamino-1-naphthalene sulfonamide to human carbonic anhydrase ii. Implications for the development of a zinc biosensor (1996) J. Biol. Chem., 271, pp. 1003-1007
Avvaru, B.S., Busby, S.A., Chalmers, M.J., Griffin, P.R., Venkatakrishnan, B., Agbandje-McKenna, M., Silverman, D.N., McKenna, R., Apo-human carbonic anhydrase ii revisited: Implications of the loss of a metal in protein structure, stability, and solvent network (2009) Biochemistry, 48, pp. 7365-7372
Hunt, J.A., Ahmed, M., Fierke, C.A., Metal binding specificity in carbonic anhydrase is influenced by conserved hydrophobic core residues (1999) Biochemistry, 38, pp. 9054-9062
DiTusa, C.A., McCall, K.A., Christensen, T., Mahapatro, M., Fierke, C.A., Toone, E.J., Thermodynamics of metal ion binding. 2. Metal ion binding by carbonic anhydrase variants (2001) Biochemistry, 40, pp. 5345-5351
McCall, K.A., Fierke, C.A., Probing determinants of the metal ion selectivity in carbonic anhydrase using mutagenesis (2004) Biochemistry, 43, pp. 3979-3986
Burton, R.E., Hunt, J.A., Fierke, C.A., Oas, T.G., Novel disulfide engineering in human carbonic anhydrase ii using the pairwise side-chain geometry database (2000) Protein Sci., 9, pp. 776-785
Mei, Y., Frederickson, C.J., Giblin, L.J., Weiss, J.H., Medvedeva, Y., Bentley, P.A., Sensitive and selective detection of zinc ions in neuronal vesicles using pydpy1, a simple turn-on dipyrrin (2011) Chem. Commun. (Camb.), 47, pp. 7107-7109
Thompson, R.B., Peterson, D., Mahoney, W., Cramer, M., Maliwal, B.P., Suh, S.W., Frederickson, C., Herman, P., Fluorescent zinc indicators for neurobiology (2002) J. Neurosci. Methods, 118, pp. 63-75
Thompson, R.B., Patchan, M.W., Lifetime-based fluorescence energy transfer biosensing of zinc (1995) Anal. Biochem., 227, pp. 123-128
Maret, W., Moulis, J.M., The bioinorganic chemistry of cadmium in the context of its toxicity (2013) Met. Ions Life Sci., 11, pp. 1-29
Cadmium-containing carbonic anhydrase CDCA1 in marine diatom Thalassiosira weissflogii
Petraglia F, Singh AA, Carafa V, Nebbioso A, Conte M, Scisciola L, Valente S, Baldi A, Mandoli A, Petrizzi VB, Ingenito C, De Falco S, Cicatiello V, Apicella I, Janssen-megens EM, Kim B, Yi G, Logie C, Heath S, Ruvo M, Wierenga ATJ, Flicek P, Yaspo ML, Della Valle V, Bernard O, Tomassi S, Novellino E, Feoli A, Sbardella G, Gut I, Vellenga E, Stunnenberg HG, Mai A, Martens JHA, Altucci L * Combined HAT/EZH2 modulation leads to cancer-selective cell death(284 views) Oncotarget (ISSN: 1949-2553electronic, 1949-2553linking), 2018 May 22; 9(39): 25630-25646. Impact Factor:5.008 ViewExport to BibTeXExport to EndNote