The role of the transcription factor nuclear factor kappa B in the regulation of cardiac hypertrophy (362 views)
High Blood Press Cardiovasc Prev High Blood Pressure And Cardiovascular Prevention (ISSN: 1120-9879), 2010; 17(4): 209-217.
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Paper type: Journal Article,
Impact factor: 0, 5-year impact factor: 0
Url: http://www.scopus.com/inward/record.url?eid=2-s2.0-79951934004&partnerID=40&md5=096a02a0cd09b432c3365769ca741dc0
Keywords: Cellular Signaling, Gene Expression, Transcription Factors, Captopril, G Protein Coupled Receptor Kinase 5, Hydralazine, I Kappa B Alpha, Immunoglobulin Enhancer Binding Protein, Protein Bcl 2, Protein P50, Synaptotagmin I, Apoptosis, Blood Pressure, Cytokine Release, Diastolic Dysfunction, Disease Course, Gene Deletion, Heart Failure, Heart Muscle Fibrosis, Heart Size, Heart Ventricle Hypertrophy, Nonhuman, Priority Journal, Review, Signal Transduction, Transcription Initiation, Vascular Resistance,
Affiliations:
Department of Clinical Medicine Cadiovascular and Immunological Sciences, University of Napoli Federico II, Napoli, Italy
References:
Berenji, K., Drazner, M.H., Rothermel, B.A., Hill, J.A., Does load-induced ventricular hypertrophy progress to systolic heart failure? (2005) American Journal of Physiology - Heart and Circulatory Physiology, 289, pp. H8-H16. , DOI 10.1152/ajpheart.01303.200
Dorn II, G.W., Force, T., Protein kinase cascades in the regulation of cardiac hypertrophy (2005) Journal of Clinical Investigation, 115 (3), pp. 527-537. , DOI 10.1172/JCI200524178
Van Empel, V.P.M., De Windt, L.J., Myocyte hypertrophy and apoptosis: A balancing act (2004) Cardiovascular Research, 63 (3), pp. 487-499. , DOI 10.1016/j.cardiores.2004.02.013, PII S0008636304001105
Chien, K.R., Knowlton, K.U., Zhu, H., Chien, S., Regulation of cardiac gene expression during myocardial growth and hypertrophy: Molecular studies of an adaptive physiologic response (1991) FASEB Journal, 5 (15), pp. 3037-3046
Morgan, H.E., Gordon, E.E., Kira, Y., Biochemical mechanisms of cardiac hypertrophy (1987) Annual Review of Physiology, 49, pp. 533-543
Wettschureck, N., Rutten, H., Zywietz, A., Gehring, D., Wilkie, T.M., Chen, J., Chien, K.R., Offermanns, S., Absence of pressure overload induced myocardial hypertrophy after conditional inactivation of Gαq/Gα11 in cardiomyocytes (2001) Nature Medicine, 7 (11), pp. 1236-1240. , DOI 10.1038/nm1101-1236
Chen, B.L., Ma, Y.D., Meng, R.S., Activation of AMPK inhibits cardiomyocyte hypertrophy by modulating of the FOXO1/MuRF1 signaling pathway in vitro (2010) Acta Pharmacol Sin, 31 (7), pp. 798-804. , Jul
Puceat, M., Vassort, G., Signalling by protein kinase C isoforms in the heart (1996) Molecular and Cellular Biochemistry, 157 (1-2), pp. 65-72
Wang, M., Wang, T., Liu, L., Expression of mitogen-activated protein kinase in hypertrophic myocardium in SHRsp (1997) Zhonghua Yi Xue Za Zhi, 77 (9), pp. 680-682. , Sep
Nagata, D., Hirata, Y., The role of AMP-activated protein kinase in the cardiovascular system (2010) Hypertens Res, 33 (1), pp. 22-28. , Jan
Palaniyandi, S.S., Sun, L., Ferreira, J.C., Protein kinase C in heart failure: A therapeutic target? (2009) Cardiovasc Res, 82 (2), pp. 229-239. , May 1
Streicher, J.M., Ren, S., Herschman, H., MAPK-activated protein kinase-2 in cardiac hypertrophy and cyclooxygenase-2 regulation in heart (2010) Circ Res, 106 (8), pp. 1434-1443. , Apr 30
Molkentin, J.D., Lu, J.-R., Antos, C.L., Markham, B., Richardson, J., Robbins, J., Grant, S.R., Olson, E.N., A calcineurin-dependent transcriptional pathway for cardiac hypertrophy (1998) Cell, 93 (2), pp. 215-228. , DOI 10.1016/S0092-8674(00)81573-1
Wilkins, B.J., Molkentin, J.D., Calcineurin and cardiac hypertrophy: Where have we been? Where are we going? (2002) Journal of Physiology, 541 (1), pp. 1-8. , DOI 10.1113/jphysiol.2002.017129
Morisco, C., Seta, K., Hardt, S.E., Glycogen synthase kinase 3beta regulates GATA4 in cardiac myocytes (2001) J Biol Chem, 276 (30), pp. 28586-28597. , Jul 27
Czubryt, M.P., Olson, E.N., Balancing contractility and energy production: The role of myocyte enhancer factor 2 (MEF2) in cardiac hypertrophy (2004) Recent Progress in Hormone Research, 59, pp. 105-124. , DOI 10.1210/rp.59.1.105
Diedrichs, H., Hagemeister, J., Chi, M., Boelck, B., Muller-Ehmsen, J., Schneider, C.A., Activation of the calcineurin/NFAT signalling cascade starts early in human hypertrophic myocardium (2007) Journal of International Medical Research, 35 (6), pp. 803-818
Liang, Q., De Windt, L.J., Witt, S.A., The transcription factors GATA4 and GATA6 regulate cardiomyocyte hypertrophy in vitro and in vivo (2001) J Biol Chem, 276 (32), pp. 30245-30253. , Aug 10
Liu, C.J., Cheng, Y.C., Lee, K.W., Lipopolysaccharide induces cellular hypertrophy through calcineurin/NFAT-3 signaling pathway in H9c2 myocardiac cells (2008) Mol Cell Biochem, 313 (1-2), pp. 167-178. , Jun
Purcell, N.H., Molkentin, J.D., Is nuclear factor κB an attractive therapeutic target for treating cardiac hypertrophy? (2003) Circulation, 108 (6), pp. 638-640. , DOI 10.1161/01.CIR.0000085362.40608.DD
Gupta, S., Purcell, N.H., Lin, A., Sen, S., Activation of nuclear factor-κB is necessary for myotrophin-induced cardiac hypertrophy (2002) Journal of Cell Biology, 159 (6), pp. 1019-1028. , DOI 10.1083/jcb.200207149
Han, J., Molkentin, J.D., Regulation of MEF2 by p38 MAPK and its implication in cardiomyocyte biology (2000) Trends in Cardiovascular Medicine, 10 (1), pp. 19-22. , DOI 10.1016/S1050-1738(00)00039-6, PII S1050173800000396
Akira, S., Uematsu, S., Takeuchi, O., Pathogen recognition and innate immunity (2006) Cell, 124 (4), pp. 783-801. , DOI 10.1016/j.cell.2006.02.015, PII S0092867406001905
Baldwin Jr., A.S., Series introduction: The transcription factor NF-kappaB and human disease (2001) J Clin Invest, 107 (1), pp. 3-6. , Jan
Beinke, S., Ley, S.C., Functions of NF-κB1 and NF-κB2 in immune cell biology (2004) Biochemical Journal, 382 (2), pp. 393-409. , DOI 10.1042/BJ20040544
Karin, M., Cao, Y., Greten, F.R., Li, Z.-W., NF-κB in cancer: From innocent bystander to major culprit (2002) Nature Reviews Cancer, 2 (4), pp. 301-310
Li, Q., Verma, I.M., NF-kappaB regulation in the immune system (2002) Nat Rev Immunol, 2 (10), pp. 725-734. , Oct
Silverman, N., Maniatis, T., NF-κB signaling pathways in mammalian and insect innate immunity (2001) Genes and Development, 15 (18), pp. 2321-2342. , DOI 10.1101/gad.909001
Bui, N.T., Livolsi, A., Peyron, J.F., Activation of nuclear factor kappaB and Bcl-x survival gene expression by nerve growth factor requires tyrosine phosphorylation of IkappaBalpha (2001) J Cell Biol, 152 (4), pp. 753-764. , Feb 19
Ghosh, S., May, M.J., Kopp, E.B., NF-κB and rel proteins: Evolutionarily conserved mediators of immune responses (1998) Annual Review of Immunology, 16, pp. 225-260. , DOI 10.1146/annurev.immunol.16.1.225
Schoonbroodt, S., Ferreira, V., Best-Belpomme, M., Boelaert, J.R., Legrand-Poels, S., Korner, M., Piette, J., Crucial role of the amino-terminal tyrosine residue 42 and the carboxyl- terminal PEST domain of IκBα in NF-κB activation by an oxidative stress (2000) Journal of Immunology, 164 (8), pp. 4292-4300
Kopp, E., Ghosh, S., Inhibition of NF-kappa B by sodium salicylate and aspirin (1994) Science, 265 (5174), pp. 956-959. , Aug 12
Traenckner, E.B., Baeuerle, P.A., Appearance of apparently ubiquitin-conjugated i kappa B-alpha during its phosphorylation-induced degradation in intact cells (1995) J Cell Sci Suppl, 19, pp. 79-84
Traenckner, E.B., Pahl, H.L., Henkel, T., Phosphorylation of human i kappa B-alpha on serines 32 and 36 controls i kappa B-alpha proteolysis and NFkappa B activation in response to diverse stimuli (1995) EMBO J, 14 (12), pp. 2876-2883. , Jun 15
Traenckner, E.B.-M., Wilk, S., Baeuerle, P.A., A proteasome inhibitor prevents activation of NF-κB and stabilizes a newly phosphorylated form of IκB-α that is still bound to NF-κB (1994) EMBO Journal, 13 (22), pp. 5433-5441
Johnson, C., Van Antwerp, D., Hope, T.J., An N-terminal nuclear export signal is required for the nucleocytoplasmic shuttling of IkappaBalpha (1999) EMBO J, 18 (23), pp. 6682-6693. , Dec 1
Gao, H., Sun, Y., Wu, Y., Luan, B., Wang, Y., Qu, B., Pei, G., Identification of β-arrestin2 as a G protein-coupled receptor-stimulated regulator of NF-κB pathways (2004) Molecular Cell, 14 (3), pp. 303-317. , DOI 10.1016/S1097-2765(04)00216-3, PII S1097276504002163
Witherow, D.S., Garrison, T.R., Miller, W.E., Lefkowitz, R.J., β-arrestin inhibits NF-κB activity by means of its interaction with the NF-κB inhibitor IκBα (2004) Proceedings of the National Academy of Sciences of the United States of America, 101 (23), pp. 8603-8607. , DOI 10.1073/pnas.0402851101
Parameswaran, N., Pao, C.S., Leonhard, K.S., Dong, S.K., Kratz, M., Ley, S.C., Benovic, J.L., Arrestin-2 and G protein-coupled receptor kinase 5 interact with NFκB1 p105 and negatively regulate lipopolysaccharide-stimulated ERK1/2 activation in macrophages (2006) Journal of Biological Chemistry, 281 (45), pp. 34159-34170. , http://www.jbc.org/cgi/reprint/281/45/34159, DOI 10.1074/jbc.M605376200
Sorriento, D., Ciccarelli, M., Santulli, G., The G-protein-coupled receptor kinase 5 inhibits NFkappaB transcriptional activity by inducing nuclear accumulation of IkappaB alpha (2008) Proc Natl Acad Sci U S A, 105 (46), pp. 17818-17823. , Nov 18
Purcell, N.H., Tang, G., Yu, C., Mercurio, F., DiDonato, J.A., Lin, A., Activation of NF-κB is required for hypertrophic growth of primary rat neonatal ventricular cardiomyocytes (2001) Proceedings of the National Academy of Sciences of the United States of America, 98 (12), pp. 6668-6673. , DOI 10.1073/pnas.111155798
Kawano, S., Kubota, T., Monden, Y., Kawamura, N., Tsutsui, H., Takeshita, A., Sunagawa, K., Blockade of NF-κB ameliorates myocardial hypertrophy in response to chronic infusion of angiotensin II (2005) Cardiovascular Research, 67 (4), pp. 689-698. , DOI 10.1016/j.cardiores.2005.04.030, PII S0008636305002142
Sorriento, D., Santulli, G., Fusco, A., Intracardiac injection of AdGRK5-NT reduces left ventricular hypertrophy by inhibiting NF-kappaB-dependent hypertrophic gene expression (2010) Hypertension, 56 (4), pp. 696-704. , Oct
Bessho, R., Matsubara, K., Kubota, M., Kuwakado, K., Hirota, H., Wakazono, Y., Lin, Y.W., Heike, T., Pyrrolidine dithiocarbamate, a potent inhibitor of nuclear factor κB (NF-κB) activation, prevents apoptosis in human promyelocytic leukemia HL-60 cells and thymocytes (1994) Biochemical Pharmacology, 48 (10), pp. 1883-1889. , DOI 10.1016/0006-2952(94)90586-X
Meiners, S., Hocher, B., Weller, A., Laule, M., Stangl, V., Guenther, C., Godes, M., Stangl, K., Downregulation of matrix metalloproteinases and collagens and suppression of cardiac fibrosis by inhibition of the proteasome (2004) Hypertension, 44 (4), pp. 471-477. , DOI 10.1161/01.HYP.0000142772.71367.65
Meiners, S., Laule, M., Rother, W., Guenther, C., Prauka, I., Muschick, P., Baumann, G., Stangl, K., Ubiquitin-proteasome pathway as a new target for the prevention of restenosis (2002) Circulation, 105 (4), pp. 483-489. , DOI 10.1161/hc0402.102951
Brown, M., McGuinness, M., Wright, T., Ren, X., Wang, Y., Boivin, G.P., Hahn, H., Jones, W.K., Cardiac-specific blockade of NF-κB in cardiac pathophysiology: Differences between acute and chronic stimuli in vivo (2005) American Journal of Physiology - Heart and Circulatory Physiology, 289, pp. H466-H476. , DOI 10.1152/ajpheart.00170.2004
Haudek, S.B., Bryant, D.D., Giroir, B.P., Differential regulation of myocardial NFκB following acute or chronic TNF-α exposure (2001) Journal of Molecular and Cellular Cardiology, 33 (6), pp. 1263-1271. , DOI 10.1006/jmcc.2001.1388
Morishita, R., Sugimoto, T., Aoki, M., Kida, I., Tomita, N., Moriguchi, A., Maeda, K., Ogihara, T., In vivo transfection of cis element 'decoy' against nuclear factor-κB binding site prevents myocardial infarction (1997) Nature Medicine, 3 (8), pp. 894-899. , DOI 10.1038/nm0897-894
Sakaguchi, T., Sawa, Y., Fukushima, N., A novel strategy of decoy transfection against nuclear factor-kappaB in myocardial preservation (2001) Ann Thorac Surg, 71 (2), pp. 624-629. , Feb discussion 9-30
Sawa, Y., Morishita, R., Suzuki, K., A novel strategy for myocardial protection using in vivo transfection of cis element decoy against NFkappaB binding site: Evidence for a role of NFkappaB in ischemia-reperfusion injury (1997) Circulation, 96 (9 SUPPL.), pp. II280-II284. , Nov 4 discussion II-5
Tomita, N., Morishita, R., Tomita, S., Yamamoto, K., Aoki, M., Matsushita, H., Hayashi, S.-I., Ogihara, T., Transcription factor decoy for nuclear factor-κB inhibits tumor necrosis factor-α-induced expression of interleukin-6 and intracellular adhesion molecule-1 in endothelial cells (1998) Journal of Hypertension, 16 (7), pp. 993-1000. , DOI 10.1097/00004872-199816070-00013
Trescher, K., Bernecker, O., Fellner, B., Gyongyosi, M., Krieger, S., DeMartin, R., Wolner, E., Podesser, B.K., Adenovirus-mediated overexpression of inhibitor kappa B-alpha attenuates postinfarct remodeling in the rat heart (2004) European Journal of Cardio-thoracic Surgery, 26 (5), pp. 960-967. , DOI 10.1016/j.ejcts.2004.07.043, PII S1010794004006190
Wang, S., Kotamraju, S., Konorev, E., Kalivendi, S., Joseph, J., Kalyanaraman, B., Activation of nuclear factor-κB during doxorubicin-induced apoptosis in endothelial cells and myocytes is pro-apoptotic: The role of hydrogen peroxide (2002) Biochemical Journal, 367 (3), pp. 729-740. , DOI 10.1042/BJ20020752
Yokoseki, O., Suzuki, J.-I., Kitabayashi, H., Watanabe, N., Wada, Y., Aoki, M., Morishita, R., Isobe, M., Cis Element decoy against nuclear factor-κB attenuates development of experimental autoimmune myocarditis in rats (2001) Circulation Research, 89 (10), pp. 899-906
Singh, S., Aggarwal, B.B., Activation of transcription factor NF-kappa B is suppressed by curcumin (diferuloylmethane) [corrected] (1995) J Biol Chem, 270 (42), pp. 24995-25000. , Oct 20
Matsumori, A., Sasayama, S., The role of inflammatory mediators in the failing heart: Immunomodulation of cytokines in experimental models of heart failure (2001) Heart Failure Reviews, 6 (2), pp. 129-136. , DOI 10.1023/A:1011457910659
Aukrust, P., Gullestad, L., Ueland, T., Damas, J.K., Yndestad, A., Inflammatory and anti-inflammatory cytokines in chronic heart failure: Potential therapeutic implications (2005) Annals of Medicine, 37 (2), pp. 74-85. , DOI 10.1080/07853890510007232
Blum, A., Miller, H., Pathophysiological role of cytokines in congestive heart failure (2001) Annual Review of Medicine, 52, pp. 15-27. , DOI 10.1146/annurev.med.52.1.15
Kukielka, G.L., Smith, C.W., Larosa, G.J., Interleukin-8 gene induction in the myocardium after ischemia and reperfusion in vivo (1995) J Clin Invest, 95 (1), pp. 89-103. , Jan
Sheng, Z., Knowlton, K., Chen, J., Hoshijima, M., Brown, J.H., Chien, K.R., Cardiotrophin 1 (CT-1) inhibition of cardiac myocyte apoptosis via a mitogen-activated protein kinase-dependent pathway. Divergence from downstream CT-1 signals for myocardial cell hypertrophy (1997) Journal of Biological Chemistry, 272 (9), pp. 5783-5791. , DOI 10.1074/jbc.272.9.5783
Kapadia, S., Lee, J., Torre-Amione, G., Tumor necrosis factor-alpha gene and protein expression in adult feline myocardium after endotoxin administration (1995) J Clin Invest, 96 (2), pp. 1042-1052. , Aug
Gwechenberger, M., Mendoza, L.H., Youker, K.A., Frangogiannis, N.G., Wayne Smith, C., Michael, L.H., Entman, M.L., Cardiac myocytes produce interleukin-6 in culture and in viable border zone of reperfused infarctions (1999) Circulation, 99 (4), pp. 546-551
Sivasubramanian, N., Coker, M.L., Kurrelmeyer, K.M., MacLellan, W.R., DeMayo, F.J., Spinale, F.G., Mann, D.L., Left ventricular remodeling in transgenic mice with cardiac restricted overexpression of tumor necrosis factor (2001) Circulation, 104 (7), pp. 826-831
Kubota, T., McTiernan, C.F., Frye, C.S., Demetris, A.J., Feldman, A.M., Cardiac-specific overexpression of tumor necrosis factor-alpha causes lethal myocarditis in transgenic mice (1997) Journal of Cardiac Failure, 3 (2), pp. 117-124
Gupta, S., Maitra, R., Young, D., Silencing the myotrophin gene by RNA interference leads to the regression of cardiac hypertrophy (2009) Am J Physiol Heart Circ Physiol, 297 (2), pp. H627-H636
Martini, J.S., Raake, P., Vinge, L.E., Uncovering G protein-coupled receptor kinase-5 as a histone deacetylase kinase in the nucleus of cardiomyocytes (2008) Proc Natl Acad Sci U S A, 105 (34), pp. 12457-12462. , Aug 26
Sorriento, D., Campanile, A., Santulli, G., Anew synthetic protein TAT-RH inhibits tumor growth through the regulation of NFkappaB activity (2009) Mol Cancer, 8, p. 97
Gupta, S., Young, D., Sen, S., Inhibition of NF-κB induces regression of cardiac hypertrophy, independent of blood pressure control, in spontaneously hypertensive rats (2005) American Journal of Physiology - Heart and Circulatory Physiology, 289, pp. H20-H29. , DOI 10.1152/ajpheart.00082.2005
Ogata, T., Miyauchi, T., Sakai, S., Takanashi, M., Irukayama-Tomobe, Y., Yamaguchi, I., Myocardial fibrosis and diastolic dysfunction in deoxycorticosterone acetate-salt hypertensive rats is ameliorated by the peroxisome proliferator-activated receptor-alpha activator fenofibrate, partly by suppressing inflammatory responses associated with the nuclear factor-kappa-B pathway (2004) Journal of the American College of Cardiology, 43 (8), pp. 1481-1488. , DOI 10.1016/j.jacc.2003.11.043, PII S0735109704001901
Ding, B., Price, R.L., Goldsmith, E.C., Borg, T.K., Yan, X., Douglas, P.S., Weinberg, E.O., Lorell, B.H., Left ventricular hypertrophy in ascending aortic stenosis mice: Anoikis and the progression to early failure (2000) Circulation, 101 (24), pp. 2854-2862
Gottlieb, R.A., Burleson, K.O., Kloner, R.A., Babior, B.M., Engler, R.L., Reperfusion injury induces apoptosis in rabbit cardiomyocytes (1994) Journal of Clinical Investigation, 94 (4), pp. 1621-1628
Kajstura, J., Cheng, W., Reiss, K., Clark, W.A., Sonnenblick, E.H., Krajewski, S., Reed, J.C., Anversa, P., Apoptotic and necrotic myocyte cell deaths are independent contributing variables of infarct size in rats (1996) Laboratory Investigation, 74 (1), pp. 86-107
Kumar, D., Kirshenbaum, L., Li, T., Danelisen, I., Singal, P., Apoptosis in isolated adult cardiomyocytes exposed to adriamycin (1999) Annals of the New York Academy of Sciences, 874, pp. 156-168. , DOI 10.1111/j.1749-6632.1999.tb09233.x
Narula, J., Haider, N., Virmani, R., Disalvo, T.G., Kolodgie, F.D., Hajjar, R.J., Schmidt, U., Khaw, B.-A., Apoptosis in myocytes in end-stage heart failure (1996) New England Journal of Medicine, 335 (16), pp. 1182-1189. , DOI 10.1056/NEJM199610173351603
Olivetti, G., Abbi, R., Quaini, F., Apoptosis in the failing human heart (1997) N Engl J Med, 336 (16), pp. 1131-1141. , Apr 17
Choi, Y.H., Cowan, D.B., Moran, A.M., Myocyte apoptosis occurs early during the development of pressure-overload hypertrophy in infant myocardium (2009) J Thorac Cardiovasc Surg, 137 (6), pp. 1356-1362. , Jun 62 e1-3
Teiger, E., Dam, T.-V., Richard, L., Wisnewsky, C., Tea, B.-S., Gaboury, L., Tremblay, J., Hamet, P., Apoptosis in pressure overload-induced heart hypertrophy in the rat (1996) Journal of Clinical Investigation, 97 (12), pp. 2891-2897
Li, Z., Bing, O.H., Long, X., Increased cardiomyocyte apoptosis during the transition to heart failure in the spontaneously hypertensive rat (1997) AmJ Physiol, 272 (5 PART 2), pp. H2313-H2319. , May
Nitahara, J.A., Cheng, W., Liu, Y., Li, B., Leri, A., Li, P., Mogul, D., Anversa, P., Intracellular calcium, DNase activity and myocyte apoptosis in aging Fischer 344 rats (1998) Journal of Molecular and Cellular Cardiology, 30 (3), pp. 519-535. , DOI 10.1006/jmcc.1997.0616
Fliss, H., Gattinger, D., Apoptosis in ischemic and reperfused rat myocardium (1996) Circulation Research, 79 (5), pp. 949-956
Bialik, S., Geenen, D.L., Sasson, I.E., Cheng, R., Horner, J.W., Evans, S.M., Lord, E.M., Kitsis, R.N., Myocyte apoptosis during acute myocardial infarction in the mouse localizes to hypoxic regions but occurs independently of p53 (1997) Journal of Clinical Investigation, 100 (6), pp. 1363-1372
Condorelli, G., Morisco, C., Stassi, G., Notte, A., Farina, F., Sgaramella, G., De Rienzo, A., Lembo, G., Increased cardiomyocyte apoptosis and changes in proapoptotic and antiapoptotic genes bax and bcl-2 during left ventricular adaptations to chronic pressure overload in the rat (1999) Circulation, 99 (23), pp. 3071-3078
Karin, M., Lin, A., NF-kappaB at the crossroads of life and death (2002) Nat Immunol, 3 (3), pp. 221-227. , Mar
Boland, M.P., Foster, S.J., O'Neill, L.A.J., Daunorubicin activates NFκB and induces κB-dependent gene expression in HL-60 promyelocytic and Jurkat T lymphoma cells (1997) Journal of Biological Chemistry, 272 (20), pp. 12952-12960. , DOI 10.1074/jbc.272.20.12952
Aoki, M., Nata, T., Morishita, R., Matsushita, H., Nakagami, H., Yamamoto, K., Yamazaki, K., Kaneda, Y., Endothelial apoptosis induced by oxidative stress through activation of NF-κB: Antiapoptotic effect of antioxidant agents on endothelial cells (2001) Hypertension, 38 (1), pp. 48-55
Kupatt, C., Wichels, R., Deiss, M., Molnar, A., Lebherz, C., Raake, P., Von Degenfeld, G., Boekstegers, P., Retroinfusion of NFκB decoy oligonucleotide extends cardioprotection achieved by CD18 inhibition in a preclinical study of myocardial ischemia and retroinfusion in pigs (2002) Gene Therapy, 9 (8), pp. 518-526. , DOI 10.1038/sj/gt/3301673
High Blood Press Cardiovasc Prev High Blood Pressure And Cardiovascular Prevention (ISSN: 1120-9879), 2010; 17(4): 209-217.
Export to BibTeX Export to EndNote
Paper type: Journal Article,
Impact factor: 0, 5-year impact factor: 0
Url: http://www.scopus.com/inward/record.url?eid=2-s2.0-79951934004&partnerID=40&md5=096a02a0cd09b432c3365769ca741dc0
Keywords: Cellular Signaling, Gene Expression, Transcription Factors, Captopril, G Protein Coupled Receptor Kinase 5, Hydralazine, I Kappa B Alpha, Immunoglobulin Enhancer Binding Protein, Protein Bcl 2, Protein P50, Synaptotagmin I, Apoptosis, Blood Pressure, Cytokine Release, Diastolic Dysfunction, Disease Course, Gene Deletion, Heart Failure, Heart Muscle Fibrosis, Heart Size, Heart Ventricle Hypertrophy, Nonhuman, Priority Journal, Review, Signal Transduction, Transcription Initiation, Vascular Resistance,
Affiliations:
Department of Clinical Medicine Cadiovascular and Immunological Sciences, University of Napoli Federico II, Napoli, Italy
References:
Berenji, K., Drazner, M.H., Rothermel, B.A., Hill, J.A., Does load-induced ventricular hypertrophy progress to systolic heart failure? (2005) American Journal of Physiology - Heart and Circulatory Physiology, 289, pp. H8-H16. , DOI 10.1152/ajpheart.01303.200
Dorn II, G.W., Force, T., Protein kinase cascades in the regulation of cardiac hypertrophy (2005) Journal of Clinical Investigation, 115 (3), pp. 527-537. , DOI 10.1172/JCI200524178
Van Empel, V.P.M., De Windt, L.J., Myocyte hypertrophy and apoptosis: A balancing act (2004) Cardiovascular Research, 63 (3), pp. 487-499. , DOI 10.1016/j.cardiores.2004.02.013, PII S0008636304001105
Chien, K.R., Knowlton, K.U., Zhu, H., Chien, S., Regulation of cardiac gene expression during myocardial growth and hypertrophy: Molecular studies of an adaptive physiologic response (1991) FASEB Journal, 5 (15), pp. 3037-3046
Morgan, H.E., Gordon, E.E., Kira, Y., Biochemical mechanisms of cardiac hypertrophy (1987) Annual Review of Physiology, 49, pp. 533-543
Wettschureck, N., Rutten, H., Zywietz, A., Gehring, D., Wilkie, T.M., Chen, J., Chien, K.R., Offermanns, S., Absence of pressure overload induced myocardial hypertrophy after conditional inactivation of Gαq/Gα11 in cardiomyocytes (2001) Nature Medicine, 7 (11), pp. 1236-1240. , DOI 10.1038/nm1101-1236
Chen, B.L., Ma, Y.D., Meng, R.S., Activation of AMPK inhibits cardiomyocyte hypertrophy by modulating of the FOXO1/MuRF1 signaling pathway in vitro (2010) Acta Pharmacol Sin, 31 (7), pp. 798-804. , Jul
Puceat, M., Vassort, G., Signalling by protein kinase C isoforms in the heart (1996) Molecular and Cellular Biochemistry, 157 (1-2), pp. 65-72
Wang, M., Wang, T., Liu, L., Expression of mitogen-activated protein kinase in hypertrophic myocardium in SHRsp (1997) Zhonghua Yi Xue Za Zhi, 77 (9), pp. 680-682. , Sep
Nagata, D., Hirata, Y., The role of AMP-activated protein kinase in the cardiovascular system (2010) Hypertens Res, 33 (1), pp. 22-28. , Jan
Palaniyandi, S.S., Sun, L., Ferreira, J.C., Protein kinase C in heart failure: A therapeutic target? (2009) Cardiovasc Res, 82 (2), pp. 229-239. , May 1
Streicher, J.M., Ren, S., Herschman, H., MAPK-activated protein kinase-2 in cardiac hypertrophy and cyclooxygenase-2 regulation in heart (2010) Circ Res, 106 (8), pp. 1434-1443. , Apr 30
Molkentin, J.D., Lu, J.-R., Antos, C.L., Markham, B., Richardson, J., Robbins, J., Grant, S.R., Olson, E.N., A calcineurin-dependent transcriptional pathway for cardiac hypertrophy (1998) Cell, 93 (2), pp. 215-228. , DOI 10.1016/S0092-8674(00)81573-1
Wilkins, B.J., Molkentin, J.D., Calcineurin and cardiac hypertrophy: Where have we been? Where are we going? (2002) Journal of Physiology, 541 (1), pp. 1-8. , DOI 10.1113/jphysiol.2002.017129
Morisco, C., Seta, K., Hardt, S.E., Glycogen synthase kinase 3beta regulates GATA4 in cardiac myocytes (2001) J Biol Chem, 276 (30), pp. 28586-28597. , Jul 27
Czubryt, M.P., Olson, E.N., Balancing contractility and energy production: The role of myocyte enhancer factor 2 (MEF2) in cardiac hypertrophy (2004) Recent Progress in Hormone Research, 59, pp. 105-124. , DOI 10.1210/rp.59.1.105
Diedrichs, H., Hagemeister, J., Chi, M., Boelck, B., Muller-Ehmsen, J., Schneider, C.A., Activation of the calcineurin/NFAT signalling cascade starts early in human hypertrophic myocardium (2007) Journal of International Medical Research, 35 (6), pp. 803-818
Liang, Q., De Windt, L.J., Witt, S.A., The transcription factors GATA4 and GATA6 regulate cardiomyocyte hypertrophy in vitro and in vivo (2001) J Biol Chem, 276 (32), pp. 30245-30253. , Aug 10
Liu, C.J., Cheng, Y.C., Lee, K.W., Lipopolysaccharide induces cellular hypertrophy through calcineurin/NFAT-3 signaling pathway in H9c2 myocardiac cells (2008) Mol Cell Biochem, 313 (1-2), pp. 167-178. , Jun
Purcell, N.H., Molkentin, J.D., Is nuclear factor κB an attractive therapeutic target for treating cardiac hypertrophy? (2003) Circulation, 108 (6), pp. 638-640. , DOI 10.1161/01.CIR.0000085362.40608.DD
Gupta, S., Purcell, N.H., Lin, A., Sen, S., Activation of nuclear factor-κB is necessary for myotrophin-induced cardiac hypertrophy (2002) Journal of Cell Biology, 159 (6), pp. 1019-1028. , DOI 10.1083/jcb.200207149
Han, J., Molkentin, J.D., Regulation of MEF2 by p38 MAPK and its implication in cardiomyocyte biology (2000) Trends in Cardiovascular Medicine, 10 (1), pp. 19-22. , DOI 10.1016/S1050-1738(00)00039-6, PII S1050173800000396
Akira, S., Uematsu, S., Takeuchi, O., Pathogen recognition and innate immunity (2006) Cell, 124 (4), pp. 783-801. , DOI 10.1016/j.cell.2006.02.015, PII S0092867406001905
Baldwin Jr., A.S., Series introduction: The transcription factor NF-kappaB and human disease (2001) J Clin Invest, 107 (1), pp. 3-6. , Jan
Beinke, S., Ley, S.C., Functions of NF-κB1 and NF-κB2 in immune cell biology (2004) Biochemical Journal, 382 (2), pp. 393-409. , DOI 10.1042/BJ20040544
Karin, M., Cao, Y., Greten, F.R., Li, Z.-W., NF-κB in cancer: From innocent bystander to major culprit (2002) Nature Reviews Cancer, 2 (4), pp. 301-310
Li, Q., Verma, I.M., NF-kappaB regulation in the immune system (2002) Nat Rev Immunol, 2 (10), pp. 725-734. , Oct
Silverman, N., Maniatis, T., NF-κB signaling pathways in mammalian and insect innate immunity (2001) Genes and Development, 15 (18), pp. 2321-2342. , DOI 10.1101/gad.909001
Bui, N.T., Livolsi, A., Peyron, J.F., Activation of nuclear factor kappaB and Bcl-x survival gene expression by nerve growth factor requires tyrosine phosphorylation of IkappaBalpha (2001) J Cell Biol, 152 (4), pp. 753-764. , Feb 19
Ghosh, S., May, M.J., Kopp, E.B., NF-κB and rel proteins: Evolutionarily conserved mediators of immune responses (1998) Annual Review of Immunology, 16, pp. 225-260. , DOI 10.1146/annurev.immunol.16.1.225
Schoonbroodt, S., Ferreira, V., Best-Belpomme, M., Boelaert, J.R., Legrand-Poels, S., Korner, M., Piette, J., Crucial role of the amino-terminal tyrosine residue 42 and the carboxyl- terminal PEST domain of IκBα in NF-κB activation by an oxidative stress (2000) Journal of Immunology, 164 (8), pp. 4292-4300
Kopp, E., Ghosh, S., Inhibition of NF-kappa B by sodium salicylate and aspirin (1994) Science, 265 (5174), pp. 956-959. , Aug 12
Traenckner, E.B., Baeuerle, P.A., Appearance of apparently ubiquitin-conjugated i kappa B-alpha during its phosphorylation-induced degradation in intact cells (1995) J Cell Sci Suppl, 19, pp. 79-84
Traenckner, E.B., Pahl, H.L., Henkel, T., Phosphorylation of human i kappa B-alpha on serines 32 and 36 controls i kappa B-alpha proteolysis and NFkappa B activation in response to diverse stimuli (1995) EMBO J, 14 (12), pp. 2876-2883. , Jun 15
Traenckner, E.B.-M., Wilk, S., Baeuerle, P.A., A proteasome inhibitor prevents activation of NF-κB and stabilizes a newly phosphorylated form of IκB-α that is still bound to NF-κB (1994) EMBO Journal, 13 (22), pp. 5433-5441
Johnson, C., Van Antwerp, D., Hope, T.J., An N-terminal nuclear export signal is required for the nucleocytoplasmic shuttling of IkappaBalpha (1999) EMBO J, 18 (23), pp. 6682-6693. , Dec 1
Gao, H., Sun, Y., Wu, Y., Luan, B., Wang, Y., Qu, B., Pei, G., Identification of β-arrestin2 as a G protein-coupled receptor-stimulated regulator of NF-κB pathways (2004) Molecular Cell, 14 (3), pp. 303-317. , DOI 10.1016/S1097-2765(04)00216-3, PII S1097276504002163
Witherow, D.S., Garrison, T.R., Miller, W.E., Lefkowitz, R.J., β-arrestin inhibits NF-κB activity by means of its interaction with the NF-κB inhibitor IκBα (2004) Proceedings of the National Academy of Sciences of the United States of America, 101 (23), pp. 8603-8607. , DOI 10.1073/pnas.0402851101
Parameswaran, N., Pao, C.S., Leonhard, K.S., Dong, S.K., Kratz, M., Ley, S.C., Benovic, J.L., Arrestin-2 and G protein-coupled receptor kinase 5 interact with NFκB1 p105 and negatively regulate lipopolysaccharide-stimulated ERK1/2 activation in macrophages (2006) Journal of Biological Chemistry, 281 (45), pp. 34159-34170. , http://www.jbc.org/cgi/reprint/281/45/34159, DOI 10.1074/jbc.M605376200
Sorriento, D., Ciccarelli, M., Santulli, G., The G-protein-coupled receptor kinase 5 inhibits NFkappaB transcriptional activity by inducing nuclear accumulation of IkappaB alpha (2008) Proc Natl Acad Sci U S A, 105 (46), pp. 17818-17823. , Nov 18
Purcell, N.H., Tang, G., Yu, C., Mercurio, F., DiDonato, J.A., Lin, A., Activation of NF-κB is required for hypertrophic growth of primary rat neonatal ventricular cardiomyocytes (2001) Proceedings of the National Academy of Sciences of the United States of America, 98 (12), pp. 6668-6673. , DOI 10.1073/pnas.111155798
Kawano, S., Kubota, T., Monden, Y., Kawamura, N., Tsutsui, H., Takeshita, A., Sunagawa, K., Blockade of NF-κB ameliorates myocardial hypertrophy in response to chronic infusion of angiotensin II (2005) Cardiovascular Research, 67 (4), pp. 689-698. , DOI 10.1016/j.cardiores.2005.04.030, PII S0008636305002142
Sorriento, D., Santulli, G., Fusco, A., Intracardiac injection of AdGRK5-NT reduces left ventricular hypertrophy by inhibiting NF-kappaB-dependent hypertrophic gene expression (2010) Hypertension, 56 (4), pp. 696-704. , Oct
Bessho, R., Matsubara, K., Kubota, M., Kuwakado, K., Hirota, H., Wakazono, Y., Lin, Y.W., Heike, T., Pyrrolidine dithiocarbamate, a potent inhibitor of nuclear factor κB (NF-κB) activation, prevents apoptosis in human promyelocytic leukemia HL-60 cells and thymocytes (1994) Biochemical Pharmacology, 48 (10), pp. 1883-1889. , DOI 10.1016/0006-2952(94)90586-X
Meiners, S., Hocher, B., Weller, A., Laule, M., Stangl, V., Guenther, C., Godes, M., Stangl, K., Downregulation of matrix metalloproteinases and collagens and suppression of cardiac fibrosis by inhibition of the proteasome (2004) Hypertension, 44 (4), pp. 471-477. , DOI 10.1161/01.HYP.0000142772.71367.65
Meiners, S., Laule, M., Rother, W., Guenther, C., Prauka, I., Muschick, P., Baumann, G., Stangl, K., Ubiquitin-proteasome pathway as a new target for the prevention of restenosis (2002) Circulation, 105 (4), pp. 483-489. , DOI 10.1161/hc0402.102951
Brown, M., McGuinness, M., Wright, T., Ren, X., Wang, Y., Boivin, G.P., Hahn, H., Jones, W.K., Cardiac-specific blockade of NF-κB in cardiac pathophysiology: Differences between acute and chronic stimuli in vivo (2005) American Journal of Physiology - Heart and Circulatory Physiology, 289, pp. H466-H476. , DOI 10.1152/ajpheart.00170.2004
Haudek, S.B., Bryant, D.D., Giroir, B.P., Differential regulation of myocardial NFκB following acute or chronic TNF-α exposure (2001) Journal of Molecular and Cellular Cardiology, 33 (6), pp. 1263-1271. , DOI 10.1006/jmcc.2001.1388
Morishita, R., Sugimoto, T., Aoki, M., Kida, I., Tomita, N., Moriguchi, A., Maeda, K., Ogihara, T., In vivo transfection of cis element 'decoy' against nuclear factor-κB binding site prevents myocardial infarction (1997) Nature Medicine, 3 (8), pp. 894-899. , DOI 10.1038/nm0897-894
Sakaguchi, T., Sawa, Y., Fukushima, N., A novel strategy of decoy transfection against nuclear factor-kappaB in myocardial preservation (2001) Ann Thorac Surg, 71 (2), pp. 624-629. , Feb discussion 9-30
Sawa, Y., Morishita, R., Suzuki, K., A novel strategy for myocardial protection using in vivo transfection of cis element decoy against NFkappaB binding site: Evidence for a role of NFkappaB in ischemia-reperfusion injury (1997) Circulation, 96 (9 SUPPL.), pp. II280-II284. , Nov 4 discussion II-5
Tomita, N., Morishita, R., Tomita, S., Yamamoto, K., Aoki, M., Matsushita, H., Hayashi, S.-I., Ogihara, T., Transcription factor decoy for nuclear factor-κB inhibits tumor necrosis factor-α-induced expression of interleukin-6 and intracellular adhesion molecule-1 in endothelial cells (1998) Journal of Hypertension, 16 (7), pp. 993-1000. , DOI 10.1097/00004872-199816070-00013
Trescher, K., Bernecker, O., Fellner, B., Gyongyosi, M., Krieger, S., DeMartin, R., Wolner, E., Podesser, B.K., Adenovirus-mediated overexpression of inhibitor kappa B-alpha attenuates postinfarct remodeling in the rat heart (2004) European Journal of Cardio-thoracic Surgery, 26 (5), pp. 960-967. , DOI 10.1016/j.ejcts.2004.07.043, PII S1010794004006190
Wang, S., Kotamraju, S., Konorev, E., Kalivendi, S., Joseph, J., Kalyanaraman, B., Activation of nuclear factor-κB during doxorubicin-induced apoptosis in endothelial cells and myocytes is pro-apoptotic: The role of hydrogen peroxide (2002) Biochemical Journal, 367 (3), pp. 729-740. , DOI 10.1042/BJ20020752
Yokoseki, O., Suzuki, J.-I., Kitabayashi, H., Watanabe, N., Wada, Y., Aoki, M., Morishita, R., Isobe, M., Cis Element decoy against nuclear factor-κB attenuates development of experimental autoimmune myocarditis in rats (2001) Circulation Research, 89 (10), pp. 899-906
Singh, S., Aggarwal, B.B., Activation of transcription factor NF-kappa B is suppressed by curcumin (diferuloylmethane) [corrected] (1995) J Biol Chem, 270 (42), pp. 24995-25000. , Oct 20
Matsumori, A., Sasayama, S., The role of inflammatory mediators in the failing heart: Immunomodulation of cytokines in experimental models of heart failure (2001) Heart Failure Reviews, 6 (2), pp. 129-136. , DOI 10.1023/A:1011457910659
Aukrust, P., Gullestad, L., Ueland, T., Damas, J.K., Yndestad, A., Inflammatory and anti-inflammatory cytokines in chronic heart failure: Potential therapeutic implications (2005) Annals of Medicine, 37 (2), pp. 74-85. , DOI 10.1080/07853890510007232
Blum, A., Miller, H., Pathophysiological role of cytokines in congestive heart failure (2001) Annual Review of Medicine, 52, pp. 15-27. , DOI 10.1146/annurev.med.52.1.15
Kukielka, G.L., Smith, C.W., Larosa, G.J., Interleukin-8 gene induction in the myocardium after ischemia and reperfusion in vivo (1995) J Clin Invest, 95 (1), pp. 89-103. , Jan
Sheng, Z., Knowlton, K., Chen, J., Hoshijima, M., Brown, J.H., Chien, K.R., Cardiotrophin 1 (CT-1) inhibition of cardiac myocyte apoptosis via a mitogen-activated protein kinase-dependent pathway. Divergence from downstream CT-1 signals for myocardial cell hypertrophy (1997) Journal of Biological Chemistry, 272 (9), pp. 5783-5791. , DOI 10.1074/jbc.272.9.5783
Kapadia, S., Lee, J., Torre-Amione, G., Tumor necrosis factor-alpha gene and protein expression in adult feline myocardium after endotoxin administration (1995) J Clin Invest, 96 (2), pp. 1042-1052. , Aug
Gwechenberger, M., Mendoza, L.H., Youker, K.A., Frangogiannis, N.G., Wayne Smith, C., Michael, L.H., Entman, M.L., Cardiac myocytes produce interleukin-6 in culture and in viable border zone of reperfused infarctions (1999) Circulation, 99 (4), pp. 546-551
Sivasubramanian, N., Coker, M.L., Kurrelmeyer, K.M., MacLellan, W.R., DeMayo, F.J., Spinale, F.G., Mann, D.L., Left ventricular remodeling in transgenic mice with cardiac restricted overexpression of tumor necrosis factor (2001) Circulation, 104 (7), pp. 826-831
Kubota, T., McTiernan, C.F., Frye, C.S., Demetris, A.J., Feldman, A.M., Cardiac-specific overexpression of tumor necrosis factor-alpha causes lethal myocarditis in transgenic mice (1997) Journal of Cardiac Failure, 3 (2), pp. 117-124
Gupta, S., Maitra, R., Young, D., Silencing the myotrophin gene by RNA interference leads to the regression of cardiac hypertrophy (2009) Am J Physiol Heart Circ Physiol, 297 (2), pp. H627-H636
Martini, J.S., Raake, P., Vinge, L.E., Uncovering G protein-coupled receptor kinase-5 as a histone deacetylase kinase in the nucleus of cardiomyocytes (2008) Proc Natl Acad Sci U S A, 105 (34), pp. 12457-12462. , Aug 26
Sorriento, D., Campanile, A., Santulli, G., Anew synthetic protein TAT-RH inhibits tumor growth through the regulation of NFkappaB activity (2009) Mol Cancer, 8, p. 97
Gupta, S., Young, D., Sen, S., Inhibition of NF-κB induces regression of cardiac hypertrophy, independent of blood pressure control, in spontaneously hypertensive rats (2005) American Journal of Physiology - Heart and Circulatory Physiology, 289, pp. H20-H29. , DOI 10.1152/ajpheart.00082.2005
Ogata, T., Miyauchi, T., Sakai, S., Takanashi, M., Irukayama-Tomobe, Y., Yamaguchi, I., Myocardial fibrosis and diastolic dysfunction in deoxycorticosterone acetate-salt hypertensive rats is ameliorated by the peroxisome proliferator-activated receptor-alpha activator fenofibrate, partly by suppressing inflammatory responses associated with the nuclear factor-kappa-B pathway (2004) Journal of the American College of Cardiology, 43 (8), pp. 1481-1488. , DOI 10.1016/j.jacc.2003.11.043, PII S0735109704001901
Ding, B., Price, R.L., Goldsmith, E.C., Borg, T.K., Yan, X., Douglas, P.S., Weinberg, E.O., Lorell, B.H., Left ventricular hypertrophy in ascending aortic stenosis mice: Anoikis and the progression to early failure (2000) Circulation, 101 (24), pp. 2854-2862
Gottlieb, R.A., Burleson, K.O., Kloner, R.A., Babior, B.M., Engler, R.L., Reperfusion injury induces apoptosis in rabbit cardiomyocytes (1994) Journal of Clinical Investigation, 94 (4), pp. 1621-1628
Kajstura, J., Cheng, W., Reiss, K., Clark, W.A., Sonnenblick, E.H., Krajewski, S., Reed, J.C., Anversa, P., Apoptotic and necrotic myocyte cell deaths are independent contributing variables of infarct size in rats (1996) Laboratory Investigation, 74 (1), pp. 86-107
Kumar, D., Kirshenbaum, L., Li, T., Danelisen, I., Singal, P., Apoptosis in isolated adult cardiomyocytes exposed to adriamycin (1999) Annals of the New York Academy of Sciences, 874, pp. 156-168. , DOI 10.1111/j.1749-6632.1999.tb09233.x
Narula, J., Haider, N., Virmani, R., Disalvo, T.G., Kolodgie, F.D., Hajjar, R.J., Schmidt, U., Khaw, B.-A., Apoptosis in myocytes in end-stage heart failure (1996) New England Journal of Medicine, 335 (16), pp. 1182-1189. , DOI 10.1056/NEJM199610173351603
Olivetti, G., Abbi, R., Quaini, F., Apoptosis in the failing human heart (1997) N Engl J Med, 336 (16), pp. 1131-1141. , Apr 17
Choi, Y.H., Cowan, D.B., Moran, A.M., Myocyte apoptosis occurs early during the development of pressure-overload hypertrophy in infant myocardium (2009) J Thorac Cardiovasc Surg, 137 (6), pp. 1356-1362. , Jun 62 e1-3
Teiger, E., Dam, T.-V., Richard, L., Wisnewsky, C., Tea, B.-S., Gaboury, L., Tremblay, J., Hamet, P., Apoptosis in pressure overload-induced heart hypertrophy in the rat (1996) Journal of Clinical Investigation, 97 (12), pp. 2891-2897
Li, Z., Bing, O.H., Long, X., Increased cardiomyocyte apoptosis during the transition to heart failure in the spontaneously hypertensive rat (1997) AmJ Physiol, 272 (5 PART 2), pp. H2313-H2319. , May
Nitahara, J.A., Cheng, W., Liu, Y., Li, B., Leri, A., Li, P., Mogul, D., Anversa, P., Intracellular calcium, DNase activity and myocyte apoptosis in aging Fischer 344 rats (1998) Journal of Molecular and Cellular Cardiology, 30 (3), pp. 519-535. , DOI 10.1006/jmcc.1997.0616
Fliss, H., Gattinger, D., Apoptosis in ischemic and reperfused rat myocardium (1996) Circulation Research, 79 (5), pp. 949-956
Bialik, S., Geenen, D.L., Sasson, I.E., Cheng, R., Horner, J.W., Evans, S.M., Lord, E.M., Kitsis, R.N., Myocyte apoptosis during acute myocardial infarction in the mouse localizes to hypoxic regions but occurs independently of p53 (1997) Journal of Clinical Investigation, 100 (6), pp. 1363-1372
Condorelli, G., Morisco, C., Stassi, G., Notte, A., Farina, F., Sgaramella, G., De Rienzo, A., Lembo, G., Increased cardiomyocyte apoptosis and changes in proapoptotic and antiapoptotic genes bax and bcl-2 during left ventricular adaptations to chronic pressure overload in the rat (1999) Circulation, 99 (23), pp. 3071-3078
Karin, M., Lin, A., NF-kappaB at the crossroads of life and death (2002) Nat Immunol, 3 (3), pp. 221-227. , Mar
Boland, M.P., Foster, S.J., O'Neill, L.A.J., Daunorubicin activates NFκB and induces κB-dependent gene expression in HL-60 promyelocytic and Jurkat T lymphoma cells (1997) Journal of Biological Chemistry, 272 (20), pp. 12952-12960. , DOI 10.1074/jbc.272.20.12952
Aoki, M., Nata, T., Morishita, R., Matsushita, H., Nakagami, H., Yamamoto, K., Yamazaki, K., Kaneda, Y., Endothelial apoptosis induced by oxidative stress through activation of NF-κB: Antiapoptotic effect of antioxidant agents on endothelial cells (2001) Hypertension, 38 (1), pp. 48-55
Kupatt, C., Wichels, R., Deiss, M., Molnar, A., Lebherz, C., Raake, P., Von Degenfeld, G., Boekstegers, P., Retroinfusion of NFκB decoy oligonucleotide extends cardioprotection achieved by CD18 inhibition in a preclinical study of myocardial ischemia and retroinfusion in pigs (2002) Gene Therapy, 9 (8), pp. 518-526. , DOI 10.1038/sj/gt/3301673
The role of the transcription factor nuclear factor kappa B in the regulation of cardiac hypertrophy
Cardiac hypertrophy is a maladaptive response to an injury, characterized by an increase in cell size, expression of fetal genes, fibrosis and apoptosis. Several signalling transduction pathways have been identified so far that are involved in this response and all of them converge on transcription factors that are the main regulator of the expression of hypertrophic genes. Among these, nuclear factor kappa B (NF-κB) is a key transcription factor regulating the expression of several genes involved in human inflammation and disease. Several reports have demonstrated the involvement of NF-κB in the regulation of cardiac hypertrophy, and different inhibitors of NF-κB activity have been described so far that are able to block NF-κB at different levels of its signalling transduction pathway. NF-κB inhibition is an effective strategy to reduce multiple aspects of cardiac hypertrophy such as cardiomyocyte size, fibrosis, inflammatory cytokines expression and apoptosis. This article focuses on recently described mechanisms of inhibition of NF-κB activity and their application to animal models of cardiac hypertrophy. All these reports add to the knowledge of NF-κB signalling and could be helpful for future studies that will be focused on the research of specific and non-toxic inhibitors of NF-κB activity to regulate cardiac hypertrophy and its evolution towards heart failure. © 2010 Adis Data Information BV. All rights reserved.
Cardiac hypertrophy is a maladaptive response to an injury, characterized by an increase in cell size, expression of fetal genes, fibrosis and apoptosis. Several signalling transduction pathways have been identified so far that are involved in this response and all of them converge on transcription factors that are the main regulator of the expression of hypertrophic genes. Among these, nuclear factor kappa B (NF-κB) is a key transcription factor regulating the expression of several genes involved in human inflammation and disease. Several reports have demonstrated the involvement of NF-κB in the regulation of cardiac hypertrophy, and different inhibitors of NF-κB activity have been described so far that are able to block NF-κB at different levels of its signalling transduction pathway. NF-κB inhibition is an effective strategy to reduce multiple aspects of cardiac hypertrophy such as cardiomyocyte size, fibrosis, inflammatory cytokines expression and apoptosis. This article focuses on recently described mechanisms of inhibition of NF-κB activity and their application to animal models of cardiac hypertrophy. All these reports add to the knowledge of NF-κB signalling and could be helpful for future studies that will be focused on the research of specific and non-toxic inhibitors of NF-κB activity to regulate cardiac hypertrophy and its evolution towards heart failure. © 2010 Adis Data Information BV. All rights reserved.
The role of the transcription factor nuclear factor kappa B in the regulation of cardiac hypertrophy
The role of the transcription factor nuclear factor kappa B in the regulation of cardiac hypertrophy
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Int J Mol Sc (ISSN: 1422-0067linking, 1661-6596, 1422-0067electronic), 2019 Jul 31; 20(15): N/D-N/D.
Impact Factor: 4.183
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Pirone L, Caldinelli L, Di Lascio S, Di Girolamo R, Di Gaetano S, Fornasari D, Pollegioni L, Benfante R, Pedone E
* Molecular insights into the role of the polyalanine region in mediating PHOX2B aggregation (278 views) (PDF 52 views)
Febs J (ISSN: 1742-464xlinking), 2019 Apr 7; 286(13): 2505-2521.
Impact Factor: 3.129
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Korotkyi OH, Vovk AA, Dranitsina AS, Falalyeyeva TM, Dvorshchenko KO, Fagoonee S, Ostapchenko LI
* The influence of probiotic diet and chondroitin sulfate administration on Ptgs2, Tgfb1 and Col2a1 expression in rat knee cartilage during monoiodoacetate-induced osteoarthritis (237 views)
Hepatology (ISSN: 0026-4806linking, 1827-1669electronic), 2019 Apr 1; 110(5): 419-424.
Impact Factor: 2.863
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Foca G, Iaccarino E, Foca A, Sanguigno L, Untiveros G, Cuevas-nunez M, Strizzi L, Leonardi A, Ruvo M, Sandomenico A
* Development of conformational antibodies targeting Cripto-1 with neutralizing effects in vitro (519 views)
Biochimie (ISSN: 0300-9084linking, 1638-6183electronic), 2019 Mar; 158: 246-256.
Impact Factor: 3.787
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Tito A, Barbulova A, Zappelli C, Leone M, Ruvo M, Mercurio FA, Chambery A, Russo R, Colucci MG, Apone F
* The Growth Differentiation Factor 11 is Involved in Skin Fibroblast Ageing and is Induced by a Preparation of Peptides and Sugars Derived from Plant Cell Cultures (280 views)
Mol Biotechnol (ISSN: 1073-6085linking, 1559-0305electronic), 2019 Mar; 61 (3 ): 209-220.
Impact Factor: 2.275
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Pirone L, Pitzer JE, D'Abrosca G, Fattorusso R, Malgieri G, Pedone EM, Pedone PV, Roop RM, Baglivo I
* Identifying the region responsible for Brucella abortus MucR higher-order oligomer formation and examining its role in gene regulation (160 views)
Sci Rep (ISSN: 2045-2322electronic, 2045-2322linking), 2018 Nov 22; 8(1): 17238-17238.
Impact Factor: 5.078
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Calvanese L, D'Auria G, Vangone A, Falcigno L, Oliva R
* Structural Basis for Mutations of Human Aquaporins Associated to Genetic Diseases (215 views)
Int J Mol Sc (ISSN: 1422-0067linking, 1422-0067electronic, 1661-6596), 2018 May 25; 19(6): N/D-N/D.
Impact Factor: 3.687
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Ferrucci V, De Antonellis P, Pennino FP, Asadzadeh F, Virgilio A, Montanaro D, Galeone A, Boffa I, Pisano I, Scognamiglio I, Navas L, Diana D, Pedone E, Gargiulo S, Gramanzini M, Brunetti A, Danielson L, Carotenuto M, Liguori L, Verrico A, Quaglietta L, Errico ME, Del Monaco V, D'Argenio V, Tirone F, Mastronuzzi A, Donofrio V, Giangaspero F, Picard D, Remke M, Garzia L, Daniels C, Delattre O, Swartling FJ, Weiss WA, Salvatore F, Fattorusso R, Chesler L, Taylor MD, Cinalli G, Zollo M
* Metastatic group 3 medulloblastoma is driven by PRUNE1 targeting NME1-TGF-beta-OTX2-SNAIL via PTEN inhibition (540 views)
Brain (ISSN: 1460-2156electronic, 0006-8950linking), 2018 May 1; 141(5): 1300-1319.
Impact Factor: 9.915
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Leggio L, Guarino F, Magrì A, Accardi-gheit R, Reina S, Specchia V, Damiano F, Tomasello MF, Tommasino M, Messina A
* Mechanism of translation control of the alternative Drosophila melanogaster Voltage Dependent Anion-selective Channel 1 mRNAs (231 views)
Sci Rep (ISSN: 2045-2322, 2045-2322electronic, 2045-2322linking), 2018 Mar 28; 8(1): 5347-5347.
Impact Factor: 4.259
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Buonanno M, Coppola M, Di Lelio I, Molisso D, Leone M, Pennacchio F, Langella E, Rao R, Monti SM
* Prosystemin, a prohormone that modulates plant defense barriers, is an intrinsically disordered protein (334 views)
Protein Sci (ISSN: 1469-896xelectronic, 0961-8368linking), 2018 Mar; 27(3): 620-632.
Impact Factor: 2.937
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Pelagalli A, Nardelli A, Lucarelli E, Zannetti A, Brunetti A
* Autocrine signals increase Ovine Mesenchymal Stem Cells migration through Aquaporin-1 and CXCR4 overexpression (625 views)
J Cell Physiol (ISSN: 1097-4652electronic, 0021-9541linking), 2018 Jan 18; 233(8): 6241-6249.
Impact Factor: 5.546
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Di Menna L, Joffe ME, Iacovelli L, Orlando R, Lindsley CW, Mairesse J, Gressèns P, Cannella M, Caraci F, Copani A, Bruno V, Battaglia G, Conn PJ, Nicoletti F
* Functional partnership between mGlu3 and mGlu5 metabotropic glutamate receptors in the central nervous system (374 views)
Neuropharm (ISSN: 0028-3908linking, 1873-7064electronic), 2018 Jan; 128: 301-313.
Impact Factor: 3.383
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Deiana M, Mettra B, Martinez-fernandez L, Mazur LM, Pawlik K, Andraud C, Samoc M, Improta R, Monnereau C, Matczyszyn K
* Specific Recognition of G-Quadruplexes Over Duplex-DNA by a Macromolecular NIR Two-Photon Fluorescent Probe (393 views)
J Phys Chem Lett (ISSN: 1948-7185, 1948-7185electronic, 1948-7185linking), 2017 Dec 7; 8(23): 5915-5920.
Impact Factor: 8.709
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Baglivo I, Pirone L, Pedone E, Pitzer JE, Muscariello L, Marino MM, Malgieri G, Freschi A, Chambery A, Roop Ii RM, Pedone PV
* Ml proteins from Mesorhizobium loti and MucR from Brucella abortus: an AT-rich core DNA-target site and oligomerization ability (231 views)
Sci Rep (ISSN: 2045-2322, 2045-2322electronic, 2045-2322linking), 2017 Nov 17; 7(1): 15805-15805.
Impact Factor: 4.122
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Zimbone S, Monaco I, Giani F, Pandini G, Copani AG, Giuffrida ML, Rizzarelli E
* Amyloid Beta monomers regulate cyclic adenosine monophosphate response element binding protein functions by activating type-1 insulin-like growth factor receptors in neuronal cells (705 views) (PDF 195 views)
Aging Cell (ISSN: 1474-9726, 1474-9718linking), 2017 Nov 01; 17(1): N/D-N/D.
Impact Factor: 7.627
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Santagata S, Portella L, Napolitano M, Greco A, D'Alterio C, Barone MV, Luciano A, Gramanzini M, Auletta L, Arra C, Zannetti A, Scala S
* A novel CXCR4-targeted near-infrared (NIR) fluorescent probe (Peptide R-NIR750) specifically detects CXCR4 expressing tumors (359 views) (PDF 203 views)
Sci Rep (ISSN: 2045-2322, 2045-2322electronic, 2045-2322linking), 2017 May 31; 7(1): 2554-2554.
Impact Factor: 4.122
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Fagoonee S, Picco G, Orso F, Arrigoni A, Longo DL, Forni M, Scarfo I, Cassenti A, Piva R, Cassoni P, Silengo L, Tolosano E, Aime S, Taverna D, Pandolfi PP, Brancaccio M, Medico E, Altruda F
* The RNA-binding protein ESRP1 promotes human colorectal cancer progression (338 views)
Oncotarget (ISSN: 1949-2553electronic, 1949-2553linking), 2016 Dec 28; 8(6): 10007-10024.
Impact Factor: 5.168
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Majkowska-skrobek G, Latka A, Berisio R, Maciejewska B, Squeglia F, RomanoM, Lavigne R, Struve C, Drulis-kawa Z
* Capsule-Targeting Depolymerase, Derived from Klebsiella KP36 Phage, as a Tool for the Development of Anti-Virulent Strategy (339 views)
Viruses-Basel (ISSN: 1999-4915), 2016 Dec 1; 8(12): N/D-N/D.
Impact Factor: 3.465
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Magri A, Di Rosa MC, Tomasello MF, Guarino F, Reina S, Messina A, De Pinto V
* Overexpression of human SOD1 in VDAC1-less yeast restores mitochondrial functionality modulating beta-barrel outer membrane protein genes (341 views)
Bba-Gen Subjects (ISSN: 0005-2728, 0006-3002print, 1570-9639print), 2016 Mar 4; 1857(6): 789-798.
Impact Factor: 4.932
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Gargiulo S, Anzilotti S, Coda AR, Gramanzini M, Greco A, Panico M, Vinciguerra A, Zannetti A, Vicidomini C, Dolle F, Pignataro G, Quarantelli M, Annunziato L, Brunetti A, Salvatore M, Pappata S
* Imaging of brain TSPO expression in a mouse model of amyotrophic lateral sclerosis with (18)F-DPA-714 and micro-PET/CT (773 views) (PDF 297 views)
Eur J Nucl Med (ISSN: 1619-7070, 1619-7089, 1619-7070print), 2016 Jan 27; 43(7): 1348-1359.
Impact Factor: 7.277
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Foca A, Sanguigno L, Foca G, Strizzi L, Iannitti R, Palumbo R, Hendrix MJ, Leonardi A, Ruvo M, Sandomenico A
* New Anti-Nodal Monoclonal Antibodies Targeting the Nodal Pre-Helix Loop Involved in Cripto-1 Binding (667 views) (PDF 261 views)
Int J Mol Sc (ISSN: 1422-0067, 1661-6596, 1422-0067linking), 2015 Sep 7; 16(9): 21342-21362.
Impact Factor: 3.257
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Cipolletta E, Rusciano MR, Maione AS, Santulli G, Sorriento D, Del Giudice C, Ciccarelli M, Franco A, Crola C, Campiglia P, Sala M, Gomez-Monterrey I, De Luca N, Trimarco B, Iaccarino G, Illario M
* Targeting the CaMKII/ERK Interaction in the Heart Prevents Cardiac Hypertrophy (260 views)
Plosone (ISSN: 1932-6203, 1932-6203electronic, 1932-6203linking), 2015 Jun 25; 10(6): e0130477-e0130477.
Impact Factor: 3.057
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Kim YH, Shin SW, Pellicano R, Fagoonee S, Choi IJ, Kim YI, Park B, Choi JM, Kim SG, Choi J, Park JY, Oh S, Yang HJ, Lim JH, Im JP, Kim JS, Jung HC, Ponzetto A, Figura N, Malfertheiner P, Choi IJ, Kook MC, Kim YI, Cho SJ, Lee JY, Kim CG, Park B, Nam BH, Bae SE, Choi KD, Choe J, Kim SO, Na HK, Choi JY, Ahn JY, Jung KW, Lee J, Kim DH, Chang HS, Song HJ, Lee GH, Jung HY, Seta T, Takahashi Y, Noguchi Y, Shikata S, Sakai T, Sakai K, Yamashita Y, Nakayama T, Leja M, Park JY, Murillo R, Liepniece-karele I, Isajevs S, Kikuste I, Rudzite D, Krike P, Parshutin S, Polaka I, Kirsners A, Santare D, Folkmanis V, Daugule I, Plummer M, Herrero R, Tsukamoto T, Nakagawa M, Kiriyama Y, Toyoda T, Cao X, Corral JE, Mera R, Dye CW, Morgan DR, Lee YC, Lin JT, Garcia Martin R, Matia Cubillo A, Lee SH, Park JM, Han YM, Ko WJ, Hahm KB, Leontiadis GI, Ford AC, Ichinose M, Sugano K, Jeong M, Park JM, Han YM, Park KY, Lee DH, Yoo JH, Cho JY, Hahm KB, Bang CS, Baik GH, Shin IS, Kim JB, Suk KT, Yoon JH, Kim YS, Kim DJ
* Helicobacter pylori Eradication for Prevention of Metachronous Recurrence after Endoscopic Resection of Early Gastric Cancer (282 views)
N Engl J Med (ISSN: 0028-4793, 0028-4793linking, 1533-4406electronic), 2015 Jun; 30642104201566393291: 749-756.
Impact Factor: 59.558
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Giacomelli C, Trincavelli ML, Satriano C, Hansson O, La Mendola D, Rizzarelli E, Martini C
* Copper (II) ions modulate Angiogenin activity in human endothelial cells (404 views)
Int J Biochem Cell B (ISSN: 1357-2725), 2015 Mar; 60: 185-196.
Impact Factor: 3.905
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Antonini D, Sirico A, Aberdam E, Ambrosio R, Campanile C, Fagoonee S, Altruda F, Aberdam D, Brissette JL, Missero C
* A composite enhancer regulates p63 gene expression in epidermal morphogenesis and in keratinocyte differentiation by multiple mechanisms (812 views)
Nucleic Acids Res (ISSN: 0305-1048, 1362-4962), 2015 Jan; 43(2): 862-874.
Impact Factor: 9.202
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Neve Polimeno M, Ierano C, D'Alterio C, Simona Losito N, Napolitano M, Portella L, Scognamiglio G, Tatangelo F, Maria Trotta A, Curley S, Costantini S, Liuzzi R, Izzo F, Scala S
* CXCR4 expression affects overall survival of HCC patients whereas CXCR7 expression does not (523 views)
Cell Mol Immunol (ISSN: 1672-7681), 2014 Nov 3; 12(4): 474-482.
Impact Factor: 4.112
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Forzati F, Federico A, Pallante P, Colamaio M, Esposito F, Sepe R, Gargiulo S, Luciano A, Arra C, Palma G, Bon G, Bucher S, Falcioni R, Brunetti A, Battista S, Fedele M, Fusco A
* CBX7 gene expression plays a negative role in adipocyte cell growth and differentiation (252 views)
Biol Open (ISSN: 2046-6390), 2014 Sep 15; 3(9): 871-879.
Impact Factor: 2.416
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Gargiulo S, Petretta MP, Greco A, Panico M, Larobina M, Gramanzini M, Schiattarella GG, Esposito G, Petretta M, Brunetti A, Cuocolo A
* Genetic deletion in uncoupling protein 3 augments 18F-fluorodeoxyglucose cardiac uptake in the ischemic heart (429 views)
Bmc Cardiovasc Disor (ISSN: 1471-2261), 2014 Sep 8; 14(1): 98-98.
Impact Factor: 1.878
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Antoniali G, Lirussi L, D'Ambrosio C, Dal Piaz F, Vascotto C, Casarano E, Marasco D, Scaloni A, Fogolari F, Tell G
* SIRT1 gene expression upon genotoxic damage is regulated by APE1 through nCaRE-promoter elements (503 views)
Mol Biol Cell (ISSN: 1059-1524), 2014 Feb 15; 25(4): 532-547.
Impact Factor: 4.466
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De Chiara L, Fagoonee S, Ranghino A, Bruno S, Camussi G, Tolosano E, Silengo L, Altruda F
* Renal cells from spermatogonial germline stem cells protect against kidney injury (326 views)
J Am Soc Nephrol (ISSN: 1046-6673), 2014 Feb; 25(2): 316-328.
Impact Factor: 9.343
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D'Ambrosio K, Lopez M, Dathan NA, Ouahrani-bettache S, Köhler S, Ascione G, Monti SM, Winum JY, De Simone G
* Structural basis for the rational design of new anti-Brucella agents: The crystal structure of the C366S mutant of l-histidinol dehydrogenase from Brucella suis (421 views)
Biochimie (ISSN: 0300-9084, 1638-6183, 0300-9084linking), 2014 Feb; 97(1): 114-120.
Impact Factor: 2.963
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Doti N, Reuther C, Scognamiglio PL, Dolga AM, Plesnila N, Ruvo M, Culmsee C
* Inhibition of the AIF/CypA complex protects against intrinsic death pathways induced by oxidative stress (532 views)
Cell Death & (ISSN: 2041-4889, 2041-4889electronic), 2014 Jan 16; 5(1): e993-e993.
Impact Factor: 5.014
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Contursi P, Farina B, Pirone L, Fusco S, Russo L, Bartolucci S, Fattorusso R, Pedone E
* Structural and functional studies of Stf76 from the Sulfolobus islandicus plasmid-virus pSSVx: a novel peculiar member of the winged helix-turn-helix transcription factor family (359 views)
Nucleic Acids Res (ISSN: 0305-1048, 1362-4962), 2014; 42(9): 5993-6011.
Impact Factor: 9.112
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Bergamo P, Cocca E, Palumbo R, Gogliettino M, Rossi M, Palmieri G
* RedOx status, proteasome and APEH: Insights into anticancer mechanisms of t10, c12-conjugated linoleic acid isomer on A375 melanoma cells (693 views)
Plosone (ISSN: 1932-6203, 1932-6203electronic, 1932-6203linking), 2013 Nov 19; 8(11): N/D-N/D.
Impact Factor: 3.534
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Del Giudice I, Limauro D, Pedone E, Bartolucci S, Fiorentino G
* A novel arsenate reductase from the bacterium Thermus thermophilus HB27: Its role in arsenic detoxification (377 views)
Bba-Gen Subjects (ISSN: 1570-9639, 0006-3002, 0925-4439), 2013 Oct; 1834(10): 2071-2079.
Impact Factor: 3.191
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Squeglia F, Bachert B, Romano M, Lukomski S, Berisio R
* Crystallization and preliminary X-ray crystallographic analysis of the variable domain of Scl2. 3, a streptococcal collagen-like protein from invasive M3-type Streptococcus pyogenes (346 views)
Nucleosides Nucleotides Nucleic Acids (ISSN: 1744-3091, 1744-4309), 2013 Sep; 69(9): 1023-1025.
Impact Factor: 0.568
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Farina B, Doti N, Pirone L, Malgieri G, Pedone E, Ruvo M, Fattorusso R
* Molecular basis of the PED/PEA15 interaction with the C-terminal fragment of phospholipase D1 revealed by NMR spectroscopy (445 views)
Bba-Gen Subjects (ISSN: 1570-9639, 0006-3002, 0925-4439), 2013 Sep; 1834(8): 1572-1580.
Impact Factor: 3.191
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Nande R, Greco A, Gossman MS, Lopez JP, Claudio L, Salvatore M, Brunetti A, Denvir J, Howard CM, Claudio PP
* Microbubble-assisted p53, RB, and p130 gene transfer in combination with radiation therapy in prostate cancer (436 views)
Current Gene Therapy (ISSN: 1875-5631, 1566-5232), 2013 Jun 1; 13(3): 163-174.
Impact Factor: 4.906
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Lombardo B, Rocco T, Esposito MT, Cantilena B, Gargiulo S, Greco A, Montanaro D, Brunetti A, Pastore L
* Thymidine Kinase-Mediated Shut Down of Bone Morphogenetic Protein-4 Expression Allows Regulated Bone Production (328 views)
Current Gene Therapy (ISSN: 1566-5232, 1875-5631), 2013 Jun 1; 13(3): 202-210.
Impact Factor: 4.906
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Romano S, Staibano S, Greco A, Brunetti A, Nappo G, Ilardi G, Martinelli R, Sorrentino A, Di Pace A, Mascolo M, Bisogni R, Scalvenzi M, Alfano B, Romano M
* FK506 binding protein 51 positively regulates melanoma stemness and metastatic potential (413 views) (PDF 240 views)
Cell Death & (ISSN: 2041-4889, 2041-4889electronic), 2013 Apr 4; 4(6): e578-e578.
Impact Factor: 5.333
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Carotenuto M, Pedone E, Diana D, de Antonellis P, Džeroski S, Marino N, Navas L, Di Dato V, Scoppettuolo MN, Cimmino F, Correale S, Pirone L, Monti SM, Bruder E, Zenko B, Slavkov I, Pastorino F, Ponzoni M, Schulte JH, Schramm A, Eggert A, Westermann F, Arrigoni G, Accordi B, Basso G, Saviano M, Fattorusso R, Zollo M
* Neuroblastoma tumorigenesis is regulated through the Nm23-H1/h-Prune C-terminal interaction (470 views)
Sci Rep (ISSN: 2045-2322, 2045-2322electronic, 2045-2322linking), 2013 Mar 1; 3: 1351-1351.
Impact Factor: 5.078
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D'Angelo D, Borbone E, Palmieri D, Uboldi S, Esposito F, Frapolli R, Pacelli R, D'Incalci M, Fusco A
* The impairment of the High Mobility Group A (HMGA) protein function contributes to the anticancer activity of trabectedin (388 views)
European Journal Of Cancer (ISSN: 0959-8049), 2013 Mar; 49(5): 1142-1151.
Impact Factor: 4.819
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Rosa R, Marciano R, Malapelle U, Formisano L, Nappi L, D'Amato C, D'Amato V, Damiano V, Marf G, Del Vecchio S, Zannetti A, Greco A, De Stefano A, Carlomagno C, Veneziani BM, Troncone G, De Placido S, Bianco R
* Sphingosine Kinase 1 Overexpression Contributes to Cetuximab Resistance in Human Colorectal Cancer Models (630 views)
Clin Cancer Res (ISSN: 1078-0432, 1078-0432linking, 1078-0432print), 2013 Jan 1; 19(1): 138-147.
Impact Factor: 8.193
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Buanne P, Renzone G, Monteleone F, Vitale M, Monti SM, Sandomenico A, Garbi C, Montanaro D, Accardo M, Troncone G, Zatovicova M, Csaderova L, Supuran CT, Pastorekova S, Scaloni A, De Simone G, Zambrano N
* Characterization of carbonic anhydrase ix interactome reveals proteins assisting its nuclear localization in hypoxic cells (363 views)
J Proteome Res (ISSN: 1535-3893), 2013 Jan; 12(1): 282-292.
Impact Factor: 5.001
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Costa B, Bendinelli S, Gabelloni P, Da Pozzo E, Daniele S, Scatena F, Vanacore R, Campiglia P, Bertamino A, Gomez-Monterrey I, Sorriento D, Del Giudice C, Iaccarino G, Novellino E, Martini C
* Human glioblastoma multiforme: p53 reactivation by a novel MDM2 inhibitor (327 views)
Plosone (ISSN: 1932-6203, 1932-6203electronic, 1932-6203linking), 2013; 8(8): e72281-e72281.
Impact Factor: 3.534
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Sorriento D, Fusco A, Ciccarelli M, Rungi A, Anastasio A, Carillo A, Dorn II GW, Trimarco B, Iaccarino G
* Mitochondrial G protein coupled receptor kinase 2 regulates proinflammatory responses in macrophages (368 views)
Febs Lett (ISSN: 0014-5793, 0014-5793print, 1873-3468electronic), 2013; 587(21): 3487-3494.
Impact Factor: 3.341
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Berisio R
* Learning from pathogens: Exploiting host-pathogen liaison for therapeutic development (365 views)
Curr Protein Pept Sci (ISSN: 1389-2037, 1389-2037linking), 2012 Dec; 13(8): 697-698.
Impact Factor: 2.326
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Forestier A, Douki T, Sauvaigo S, De Rosa V, Demeilliers C, Rachidi W
* Alzheimer's disease-associated neurotoxic peptide amyloid-beta impairs base excision repair in human neuroblastoma cells (441 views)
Int J Mol Sc (ISSN: 1422-0067linking, 1422-0067electronic, 1661-6596), 2012 Nov 13; 13(11): 14766-14787.
Impact Factor: 2.464
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Sorriento D, Illario M, Finelli R, Iaccarino G
* To NFkappaB or not to NFkappaB: The Dilemma on How to Inhibit a Cancer Cell Fate Regulator (246 views)
Transl Med Unisa (ISSN: 2239-9747electronic, 2239-9747linking), 2012 Oct 11; 4: 73-85.
Impact Factor: 2.256
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Finetti F, Basile A, Capasso D, Di Gaetano S, Di Stasi R, Pascale M, Turco CM, Ziche M, Morbidelli L, D'Andrea LD
* Functional and pharmacological characterization of a VEGF mimetic peptide on reparative angiogenesis (562 views)
Biochem Pharmacol Biochemical Pharmacology (ISSN: 0006-2952, 1873-2968), 2012 Sep 1; 84(3): 303-311.
Impact Factor: 4.576
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Riccio A, Cubellis MV
* Gain of function in CDKN1C (495 views)
Nature Genetics (ISSN: 1061-4036), 2012 Jul; 44(7): 737-738.
Impact Factor: 35.209
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Pedicini P, Caivano R, Jereczek-Fossa BA, Strigari L, Vischioni B, Alterio D, Cremonesi M, Botta F, Nappi A, Improta G, Storto G, Benassi M, Orecchia R
* Modelling the correlation between EGFr expression and tumour cell radiosensitivity, and combined treatments of radiation and monoclonal antibody EGFr inhibitors (364 views)
Theor Biol Med Model (ISSN: 1742-4682), 2012 Jun 19; 9(1): 23-23.
Impact Factor: 1.461
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Avitabile C, Moggio L, Malgieri G, Capasso D, Di Gaetano S, Saviano M, Pedone C, Romanelli A
* Gamma Sulphate Pna (pna S): Highly Selective Dna Binding Molecule Showing Promising Antigene Activity (425 views)
Plosone (ISSN: 1932-6203, 1932-6203electronic, 1932-6203linking), 2012 May 7; 7(5): e35774-e35774.
Impact Factor: 3.73
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Calafiore M, Copani A, Deng W
* DNA polymerase-β mediates the neurogenic effect of β-amyloid protein in cultured subventricular zone neurospheres (557 views)
Journal Of Neuroscience Research (ISSN: 0360-4012), 2012 Mar; 90(3): 559-567.
Impact Factor: 2.974
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Langlois C, Del Gatto A, Arseneault G, Lafrance-vanasse J, De Simone M, Morse T, De Paola I, Lussier-price M, Legault P, Pedone C, Zaccaro L, Omichinski JG
* Structure-based design of a potent artificial transactivation domain based on p53 (398 views)
J Am Chem Soc (ISSN: 1520-5126, 0002-2786, 0002-7863), 2012 Jan 25; 134(3): 1715-1723.
Impact Factor: 5.65
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Caraci F, Spampinato S, Sortino MA, Bosco P, Battaglia G, Bruno V, Drago F, Nicoletti F, Copani A
* Dysfunction of TGF-β1 signaling in Alzheimer's disease: Perspectives for neuroprotection (819 views)
Cell Tissue Res (ISSN: 0302-766x), 2012 Jan; 347(1): 291-301.
Impact Factor: 3.677
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Gargiulo S, Greco A, Gramanzini M, Petretta MP, Ferro A, Larobina M, Panico M, Brunetti A, Cuocolo A
* PET/CT imaging in mouse models of myocardial ischemia (647 views)
J Biomed Biotechnol (ISSN: 1110-7251, 1110-7243), 2012; 2012: 541872-541872.
Impact Factor: 2.88
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Viparelli F, Doti N, Sandomenico A, Marasco D, Dathan NA, Miele C, Beguinot F, Monti SM, Ruvo M
* GSM48878: CD8 IL2-D2 (378 views)
Gene Expression Omnibus, 2011 Dec 2; 59(2): 302-308.
Impact Factor: 2.082
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Di Paola R, Impellizzeri D, Salinaro AT, Mazzon E, Bellia F, Cavallaro M, Cornelius C, Vecchio G, Calabrese V, Rizzarelli E, Cuzzocrea S
* Administration of carnosine in the treatment of acute spinal cord injury (562 views)
Biochem Pharmacol Biochemical Pharmacology (ISSN: 1873-2968, 0006-2952), 2011 Nov 15; 82(10): 1478-1489.
Impact Factor: 4.705
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Malgieri G, Zaccaro L, Leone M, Bucci E, Esposito S, Baglivo I, Del Gatto A, Russo L, Scandurra R, Pedone PV, Fattorusso R, Isernia C
* Zinc to Cadmium Replacement in the A. thaliana SUPERMAN Cys(2)His(2) Zinc Finger Induces Structural Rearrangements of Typical DNA Base Determinant Positions (423 views)
Biopolymers (ISSN: 0006-3525, 0006-6352, 0006-3525print), 2011 Nov; 95(11): 801-810.
Impact Factor: 2.87
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Palmieri D, Valentino T, D'Angelo D, De Martino I, Postiglione I, Pacelli R, Croce CM, Fedele M, Fusco A
* HMGA proteins promote ATM expression and enhance cancer cell resistance to genotoxic agents (765 views)
Oncogene (ISSN: 0950-9232, 1476-5594), 2011 Jul 7; 30(27): 3024-3035.
Impact Factor: 6.373
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Scognamiglio PL, Doti N, Grieco P, Pedone C, Ruvo M, Marasco D
* Discovery Of Small Peptide Antagonists Of Ped/Pea15-D4alpha Interaction From Simplified Combinatorial Libraries (447 views)
Chem Biol Drug Des (ISSN: 1747-0277, 1747-0285), 2011 May; 77(5): 319-327.
Impact Factor: 2.282
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Caraci F, Molinaro G, Battaglia G, Giuffrida ML, Riozzi B, Traficante A, Bruno V, Cannella M, Merlo S, Wang X, Heinz BA, Nisenbaum ES, Britton TC, Drago F, Sortino MA, Copani A, Nicoletti F
* Targeting group II Metabotropic Glutamate (mGlu) receptors for the treatment of psychosis associated with alzheimer's disease: Selective activation of mGlu2 receptors amplifies β-amyloid toxicity in cultured neurons, whereas dual activation of mGlu2 and mGlu3 receptors is neuroprotective (715 views)
Mol Pharmacol (ISSN: 0026-895x), 2011 Mar; 79(3): 618-626.
Impact Factor: 4.883
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Pizzo E, Merlino A, Turano M, Russo Krauss I, Coscia F, Zanfardino A, Varcamonti M, Furia A, Giancola C, Mazzarella L, Sica F, D'Alessio G
* A new RNase sheds light on the RNase/angiogenin subfamily from zebrafish (741 views)
Biochem J (ISSN: 1470-8728electronic, 0264-6021linking, 0264-6021print), 2011 Jan 15; 433(2): 345-355.
Impact Factor: 4.897
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Ruggiero A, Squeglia F, Pirone L, Correale S, Berisio R
* Expression, purification, crystallization and preliminary X-ray crystallographic analysis of a major fragment of the resuscitation-promoting factor RpfB from Mycobacterium tuberculosis (374 views)
Nucleosides Nucleotides Nucleic Acids (ISSN: 1744-3091, 1744-4309), 2011 Jan 1; 67(1): 164-168.
Impact Factor: 0.506
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Ciccarelli M, Sorriento D, Cipolletta E, Santulli G, Fusco A, Zhou R-H, Eckhart AD, Peppel K, Koch WJ, Trimarco B, Iaccarino G
* Impaired neoangiogenesis in β2-adrenoceptor gene-deficient mice: Restoration by intravascular human β2-adrenoceptor gene transfer and role of NFkB and CREB transcription factors (352 views)
Br J Pharmacol British Journal Of Pharmacology (ISSN: 0007-1188), 2011; 162(3): 712-721.
Impact Factor: 4.409
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Spina-Purrello V, Giliberto S, Barresi V, Nicoletti VG, Giuffrida Stella AM, Rizzarelli E
* Modulation of PARP-1 and PARP-2 expression by L-carnosine and trehalose after LPS and INFγ-induced oxidative stress (420 views)
Neurochemical Research (ISSN: 0364-3190, 1573-6903), 2010 Dec; 35(12): 2144-2153.
Impact Factor: 2.608
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Amorosi S, Vigliano I, Del Giudice E, Panico L, Maruotti GM, Fusco A, Quarantelli M, Ciccone C, Ursini MV, Martinelli P, Pignata C
* Brain alteration in a Nude/SCID fetus carrying FOXN1 homozygous mutation (393 views)
J Neurol Sci (ISSN: 0022-510x), 2010 Nov 15; 298(1-2): 121-123.
Impact Factor: 2.167
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Calvanese L, Marasco D, Doti N, Saporito A, D'Auria G, Paolillo L, Ruvo M, Falcigno L
* Structural Investigations on the Nodal-Cripto Binding: A Theoretical and Experimental Approach (485 views)
Biopolymers (ISSN: 0006-3525, 0006-6352, 0006-3525print), 2010 Nov; 93(11): 1011-1021.
Impact Factor: 2.572
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Farina B, Pirone L, Russo L, Viparelli F, Doti N, Pedone C, Pedone E, Fattorusso R
* NMR backbone dynamics studies of human PED/PEA-15 outline protein functional sites (641 views)
Febs J (ISSN: 1742-4658, 1742-464x, 1742-4658electronic), 2010 Oct; 277(20): 4229-4240.
Impact Factor: 3.129
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Doti N, Cassese A, Marasco D, Paturzo F, Sabatella M, Viparelli F, Dathan N, Monti SM, Miele C, Formisano P, Beguinot F, Ruvo M
* Residues 762-801 of PLD1 mediate the interaction with PED/PEA15 (457 views)
Mol Biosyst (ISSN: 1742-206x), 2010 Oct; 6(10): 2039-2048.
Impact Factor: 3.825
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Alterio V, Aurilia V, Romanelli A, Parracino A, Saviano M, D'Auria S, De Simone G
* Crystal structure of an S-formylglutathione hydrolase from pseudoalteromonas haloplanktis TAC125 (354 views)
Biopolymers (ISSN: 0006-3525, 0006-6352, 0006-3525print), 2010 Sep; 93(8): 669-677.
Impact Factor: 2.572
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Pensato S, Saviano M, Bianchi N, Borgatti M, Fabbri E, Gambari R, Romanelli A
* Gamma-Hydroxymethyl Pnas: Synthesis, Interaction With Dna And Inhibition Of Protein/Dna Interactions (350 views)
Bioorg Chem, 2010 Sep; 38(5): 196-201.
Impact Factor: 2.141
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Bombardieri E, Ambrosini V, Aktolun C, Baum RP, Bishof-delaloye A, Del Vecchio S, Maffioli L, Mortelmans L, Oyen W, Pepe G, Chiti A
* In-111-pentetreotide scintigraphy: procedure guidelines for tumour imaging (467 views)
Eur J Nucl Med (ISSN: 1619-7070, 1619-7089, 0340-6997), 2010 Jul; 37(7): 1441-1448.
Impact Factor: 5.036
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Pensato S, Renda M, Leccia F, Saviano M, D'Andrea LD, Pedone C, Pedone PV, Romanelli A
* PNA zipper as a dimerization tool: development of a bZip mimic (477 views)
Biopolymers (ISSN: 0006-3525, 0006-6352, 0006-3525print), 2010 May; 93(5): 434-441.
Impact Factor: 2.572
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Canettieri G, Di Marcotullio L, Greco A, Coni S, Antonucci L, Infante P, Pietrosanti L, De Smaele E, Ferretti E, Miele E, Pelloni M, De Simone G, Pedone E, Gallinari P, Giorgi A, Steinkuhler C, Vitagliano L, Pedone C, Schinin ME, Screpanti I, Gulino A
* Histone deacetylase and Cullin3-REN(KCTD11) ubiquitin ligase interplay regulates Hedgehog signalling through Gli acetylation (575 views)
Nature Cell Biol Nature Cell Biology (ISSN: 1476-4679, 1465-7392), 2010 Feb; 12(2): 132-142.
Impact Factor: 19.407
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Orsi S, De Capua A, Guarnieri D, Marasco D, Netti PA
* Cell recruitment and transfection in gene activated collagen matrix (371 views)
Biomaterials (ISSN: 0142-9612, 1878-5905electronic, 0142-9612linking), 2010 Jan; 31(3): 570-576.
Impact Factor: 7.883
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Sorriento D, Santulli G, Fusco A, Anastasio A, Trimarco B, Iaccarino G
* Intracardiac injection of AdGRK5-NT reduces left ventricular hypertrophy by inhibiting NF-κB-Dependent hypertrophic gene expression (378 views)
Hypertensionhypertension (ISSN: 0194-911x), 2010; 56(4): 696-704.
Impact Factor: 6.908
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Galasso G, De Rosa R, Piscione F, Iaccarino G, Vosa C, Sorriento D, Piccolo R, Rapacciuolo A, Walsh K, Chiariello M
* Myocardial expression of FOXO3a-Atrogin-1 pathway in human heart failure (246 views)
Eur J Heart Fail European Journal Of Heart Failure (ISSN: 1388-9842), 2010; 12(12): 1290-1296.
Impact Factor: 4.512
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D'Antò V, Michelotti A, Esposito L, Zagari A, Liguori R, Sacchetti L
* Nonsynonimous mutation of catechol-O-methyl-transferase (COMT) gene in a patient with temporomandibular disorder (332 views)
J Sci Med Sport (ISSN: 1440-2440), 2010; 13(6): 174-179.
Impact Factor: 3.194
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Calabrese V, Cornelius C, Rizzarelli E, Owen JB, Dinkova-Kostova AT, Butterfield DA
* Nitric oxide in cell survival: a janus molecule (593 views)
Antioxid Redox Signal (ISSN: 1557-7716, 1523-0864, 1523-0864linking), 2009 Nov; 11(11): 2717-2739.
Impact Factor: 7.581
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Marasco D, Stilo R, Sandomenico A, Monti SM, Tizzano B, De Capua A, Varricchio E, Liguoro D, Zotti T, Formisano S, Ruvo M, Vito P
* Generation And Functional Characterization Of A Bcl10-Inhibitory Peptide That Represses Nf-Kappa B Activation (379 views)
Biochem J (ISSN: 0264-6021, 1470-8728electronic, 0264-6021linking), 2009 Sep 15; 422(3): 553-561.
Impact Factor: 5.155
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D'Andrea LD, Del Gatto A, De Rosa L, Romanelli A, Pedone C
* Peptides targeting angiogenesis related growth factor receptors (14425 views)
Curr Pharm Des Current Pharmaceutical Design (ISSN: 1873-4286, 1381-6128), 2009 Jul; 15(21): 2414-2429.
Impact Factor: 4.414
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Sandomenico A, Monti SM, Sabatella M, De Capua A, Tornatore L, Doti N, Viparelli F, Dathan NA, Pedone C, Ruvo M, Marasco D
* Protein-protein interactions: a simple strategy to identify binding sites and peptide antagonists (439 views)
Chem Biol Drug Des (ISSN: 1747-0285, 1747-0277), 2009 May; 73(5): 483-493.
Impact Factor: 2.473
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Ierano C, Giuliano P, D'Alterio C, Cioffi M, Mettivier V, Portella L, Napolitano M, Barbieri A, Arra C, Liguori G, Franco R, Palmieri G, Rozzo C, Pacelli R, Castello G, Scala S
* A point mutation (G574A) in the chemokine receptor CXCR4 detected in human cancer cells enhances migration (375 views)
Cell Cycle (ISSN: 1538-4101), 2009 Apr 15; 8(8): 1228-1237.
Impact Factor: 4.087
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Garzia L, Andolfo I, Cusanelli E, Marino N, Petrosino G, De Martino D, Esposito V, Galeone A, Navas L, Esposito S, Gargiulo S, Fattet S, Donofrio V, Cinalli G, Brunetti A, Del Vecchio L, Northcott PA, Delattre O, Taylor MD, Iolascon A, Zollo M
* MicroRNA-199b-5p Impairs Cancer Stem Cells through Negative Regulation of HES1 in Medulloblastoma (426 views)
Plosone (ISSN: 1932-6203, 1932-6203electronic, 1932-6203linking), 2009 Mar 24; 4(3): e4998-e4998.
Impact Factor: 4.351
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Calvanese L, Saporito A, Oliva R, D'Auria G, Pedone C, Paolillo L, Ruvo M, Marasco D, Falcigno L
* Structural insights into the interaction between the Cripto CFC domain and the ALK4 receptor (443 views)
J Pept Sci (ISSN: 1075-2617, 1099-1387, 1075-2617print), 2009 Mar; 15(3): 175-183.
Impact Factor: 1.807
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Francalanci F, Avolio M, De Luca E, Longo DL, Menchise V, Guazzi P, Sgro F, Marino M, Goitre L, Balzac F, Trabalzini L, Retta SF
* Structural and functional differences between KRIT1A and KRIT1B isoforms: A framework for understanding CCM pathogenesis (485 views)
Exp Cell Res (ISSN: 0014-4827), 2009 Jan 15; 315(2): 285-303.
Impact Factor: 3.589
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Sorriento D, Campanile A, Santulli G, Leggiero E, Pastore L, Trimarco B, Iaccarino G
* A new synthetic protein, TAT-RH, inhibits tumor growth through the regulation of NFκB activity (341 views)
Mol Cancermolecular Cancer (ISSN: 1476-4598), 2009; 8: N/D-N/D.
Impact Factor: 4.16
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Arpaia P, Clemente F, Manna C, Montenero G
* Automatic modeling based on cultural programming for osseointegration diagnosis (275 views)
Vols 1 3i2mtc (ISSN: 1091-5281), 2009; N/D: 1278-1283.
Impact Factor: 0
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Lucignani G, Salvatore M
* Biotechnology in molecular and cellular imaging (262 views)
Minerva Biotecnol (ISSN: 1120-4826), 2009; 21(1): 1-3.
Impact Factor: 0.268
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Ponticelli S, Marasco D, Tarallo V, Albuquerque RJC, Mitola S, Takeda A, Stassen J, Presta M, Ambati J, Ruvo M, De Falco S
* Modulation of Angiogenesis by a Tetrameric Tripeptide That Antagonizes Vascular Endothelial Growth Factor Receptor (465 views)
Jbc Papers (ISSN: 0021-9258, 1083-351x, 0021-9258linking), 2008 Dec 5; 283(49): 34250-34259.
Impact Factor: 5.52
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Caraci F, Busceti C, Biagioni F, Aronica E, Mastroiacovo F, Cappuccio I, Battaglia G, Bruno V, Caricasole A, Copani A, Nicoletti
* The Wnt antagonist, Dickkopf-1, as a target for the treatment of neurodegenerative disorders (362 views)
Neurochemical Research (ISSN: 0364-3190, 1573-6903), 2008 Dec; 33(12): 2401-2406.
Impact Factor: 2.26
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Galdiero S, Falanga A, Vitiello M, Raiola L, Fattorusso R, Browne H, Pedone C, Isernia C, Galdiero M
* Analysis of a membrane interacting region of herpes simplex virus type 1 glycoprotein (538 views)
Jbc Papers (ISSN: 0021-9258, 1083-351x, 0021-9258linking), 2008 Oct 31; 283(44): 29993-30009.
Impact Factor: 5.52
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Castiglione M, Calafiore M, Costa L, Sortino MA, Nicoletti F, Copani A
* Group I metabotropic glutamate receptors control proliferation, survival and differentiation of cultured neural progenitor cells isolated from the subventricular zone of adult mice (416 views)
Neuropharm (ISSN: 0028-3908, 1873-7064electronic, 0028-3908linking), 2008 Sep; 55(4): 560-567.
Impact Factor: 3.383
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Viparelli F, Doti N, Sandomenico A, Marasco D, Dathan NA, Miele C, Beguinot F, Monti SM, Ruvo M
* Expression and purification of the D4 region of PLD1 and characterization of its interaction with PED-PEA15 (421 views)
Protein Expr Purif (ISSN: 1046-5928), 2008 Jun; 59(2): 302-308.
Impact Factor: 1.621
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Sbardella G, Castellano S, Vicidomini C, Rotili D, Nebbioso A, Miceli M, Altucci L, Mai A
* Identification of long chain alkylidenemalonates as novel small molecule modulators of histone acetyltransferases (285 views)
Bioorganic & Medicinal Chemistry Letters (ISSN: 0960-894x), 2008 May 1; 18(9): 2788-2792.
Impact Factor: 2.531
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Limauro D, Pedone E, Galdi I, Bartolucci S
* Peroxiredoxins as cellular guardians in Sulfolobus solfataricus - characterization of Bcp1, Bcp3 and Bcp4 (354 views)
Febs Journal (ISSN: 1742-464x), 2008 May; 275(9): 2067-2077.
Impact Factor: 3.139
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Goldfine ID, Maddux BA, Youngren JF, Reaven G, Accili D, Trischitta V, Vigneri R, Frittitta L
* The role of membrane glycoprotein plasma cell antigen 1 ectonucleotide pyrophosphatase phosphodiesterase 1 in the pathogenesis of insulin resistance and related abnormalities (629 views)
Endocrine Reviews (ISSN: 0163-769x), 2008 Feb; 29(1): 62-75.
Impact Factor: 18.562
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Marchelli R, Saviano M, Licandro E, Spoto G, Borgatti M, Gambari R
* PNAs targeting the "RNA world": Micro RNA next? (384 views)
Minerva Biotecnol (ISSN: 1120-4826), 2008; 20(4): 183-188.
Impact Factor: 0.1
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Malaguarnera R, Vella V, Pandini G, Sanfilippo M, Pezzino V, Vigneri R, Frasca F
* TAp73α increases p53 tumor suppressor activity in thyroid cancer cells via the inhibition of Mdm2-mediated degradation (411 views)
Mol Cancer Res (ISSN: 1541-7786), 2008; 6(1): 64-77.
Impact Factor: 4.533
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Sorriento D, Ciccarelli M, Santulli G, Campanile A, Altobelli GG, Cimini V, Galasso G, Astone D, Piscione F, Pastore L, Trimarco B, Iaccarino G
* The G-protein-coupled receptor kinase 5 inhibits NFκB transcriptional activity by inducing nuclear accumulation of IκBα (419 views)
P Natl Acad Sci Usa (ISSN: 0027-8424, 1091-6490, 0027-8424print), 2008; 105(46): 17818-17823.
Impact Factor: 9.38
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Ruggiero A, Tizzano B, Geerlof A, Pedone E, Pedone C, Wilmanns M, Berisio R
* Expression, purification, crystallization and preliminary X-ray crystallographic analysis of a resuscitation-promoting factor from Mycobacterium tuberculosis (363 views)
Nucleosides Nucleotides Nucleic Acids (ISSN: 1744-3091, 1744-4309), 2007 Oct 1; 63(10): 870-873.
Impact Factor: 0.645
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Pensato S, Saviano M, Romanelli A
* New peptide nucleic acid analogues: synthesis and applications (457 views)
Expert Opinion On Biological Therapy (ISSN: 1471-2598), 2007 Sep; 7(8): 1219-1232.
Impact Factor: 2.815
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Limauro D, Pedone E, Pirone L, Bartolucci S
* Identification and characterization of 1-Cys peroxiredoxin from Sulfolobus solfataricus and its involvement in the response to oxidative stress (332 views)
Febs Journal (ISSN: 1742-464x), 2006 Feb; 273(4): 721-731.
Impact Factor: 3.033
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Copani A, Hoozemans JJM, Caraci F, Calafiore M, Van Haastert ES, Veerhuis R, Rozemuller AJM, Aronica E, Sortino MA, Nicoletti F
* Dna Polymerase-Beta Is Expressed Early In Neurons Of Alzheimer'S Disease Brain And Is Loaded Into Dna Replication Forks In Neurons Challenged With Beta-Amyloid (461 views)
J Neurosci (ISSN: 0270-6474, 0361-803x, 1529-2401), 2006; 26(43): 10949-10957.
Impact Factor: 2.117
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Fiory F, Alberobello AT, Miele C, Oriente F, Esposito I, Corbo V, Ruvo M, Tizzano B, Rasmussen TE, Gammeltoft S, Formisano P, Beguinot F
* Tyrosine phosphorylation of phosphoinositide-dependent kinase 1 by the insulin receptor is necessary for insulin metabolic signaling (450 views)
Mol Cell Biol (ISSN: 0270-7306, 1098-5549), 2005 Dec; 25(24): 10803-10814.
Impact Factor: 7.093
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Foti D, Chiefari E, Fedele M, Iuliano R, Brunetti L, Paonessa F, Manfioletti G, Barbetti F, Brunetti A, Croce CM, Fusco A, Brunetti A
* Lack of the architectural factor HMGA1 causes insulin resistance and diabetes in humans and mice (375 views)
Nat Med (ISSN: 1078-8956, 0034-7264), 2005 Jul; 11(7): 765-773.
Impact Factor: 28.878
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Saviano M, Isernia C, Bassarello C, Di Lello P, Galdiero S, Mierke DF, Benedetti E, Pedone C
* Conformational analysis by NMR and distance geometry techniques of a peptide mimetic of the third helix of the Antennapedia homeodomain (429 views)
J Pept Res (ISSN: 1397-002x), 2005 Feb; 65(2): 200-208.
Impact Factor: 1.741
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Borgatti M, Boyd DD, Lampronti I, Bianchi N, Fabbri E, Saviano M, Romanelli A, Pedone C, Gambari R
* Decoy molecules based on PNA-DNA chimeras and targeting Sp1 transcription factors inhibit the activity of urokinase-type plasminogen activator receptor (uPAR) promoter (384 views)
Oncology Research (ISSN: 0965-0407), 2005; 15(7-8): 373-383.
Impact Factor: 1.844
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Rivieccio V, Mannini R, Concilio L, D'Auria S, Pedone C, Grimaldi G
* Expression, purification and partial characterization of the Krüppel-associated box (KRAB) from the human ZNF2 protein (278 views)
Protein Pept Lett (ISSN: 0929-8665, 1875-5305), 2005; 12(6): 527-532.
Impact Factor: 0.84
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Borgatti M, Finotti A, Romanelli A, Saviano M, Bianchi N, Lampronti I, Lambertini E, Penolazzi L, Nastruzzi C, Mischiati C, Piva R, Pedone C, Gambari R
* Peptide nucleic acids (PNA)-DNA chimeras targeting transcription factors as a tool to modify gene expression (470 views)
Curr Drug Targets (ISSN: 1389-4501), 2004 Nov; 5(8): 735-744.
Impact Factor: 4.104
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Penolazzi L, Borgatti M, Lambertini E, Mischiati C, Finotti A, Romanelli A, Saviano M, Pedone C, Piva R, Gambari R
* Peptide nucleic acid-DNA decoy chimeras targeting NF-kappa B transcription factors: Induction of apoptosis in human primary osteoclasts (306 views)
International Journal Of Molecular Medicine (ISSN: 1107-3756), 2004 Sep; 14(2): 145-152.
Impact Factor: 3.19
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Caricasole A, Copani A, Caraci F, Aronica E, Rozemuller AJ, Caruso A, Storto M, Gaviraghi G, Terstappen GC, Nicoletti F
* Induction of Dickkopf-1, a negative modulator of the Wnt pathway, is associated with neuronal degeneration in Alzheimer's brain (498 views)
J Neurosci (ISSN: 0270-6474, 0361-803x, 1529-2401), 2004 Jun 30; 24(26): 6021-6027.
Impact Factor: 2.384
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Isernia C, Bucci E, Leone M, Zaccaro L, Di Lello P, Digilio G, Esposito S, Saviano M, Di Blasio B, Pedone C, Pedone PV, Fattorusso R
* NMR structure of the single QALGGH zinc finger domain from the Arabidopsis thaliana SUPERMAN protein (412 views)
Chembiochem (ISSN: 1439-4227, 1439-7633, 1439-7633electronic), 2003 Mar 3; 4(2-3): 171-180.
Impact Factor: 3.992
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Esposito G, Ligresti A, Izzo AA, Bisogno T, Ruvo M, Di Rosa M, Di Marzo V, Iuvone T
* The endocannabinoid system protects rat glioma cells against HIV-1 Tat protein-induced cytotoxicity: Mechanism and regulation (459 views)
Jbc Papers (ISSN: 0021-9258, 1083-351x, 0021-9258linking), 2002 Dec 27; 277(52): 50348-50354.
Impact Factor: 6.696
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Dathan N, Zaccaro L, Esposito S, Isernia C, Omichinski JG, Riccio A, Pedone C, Di Blasio B, Fattorusso R, Pedone PV
* The Arabidopsis SUPERMAN protein is able to specifically bind DNA through its single Cys(2)-His(2) zinc finger motif (550 views)
Nucleic Acids Res (ISSN: 0305-1048, 1362-4962, 1362-4962electronic), 2002 Nov 15; 30(22): 4945-4951.
Impact Factor: 7.051
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Borgatti M, Breda L, Cortesi R, Nastruzzi C, Romanelli A, Saviano M, Bianchi N, Mischiati C, Pedone C, Gambari R
* Cationic Liposomes As Delivery Systems For Double-Stranded Pna-Dna Chimeras Exhibiting Decoy Activity Against Nf-Kappab Transcription Factors (395 views)
Biochem Pharmacol Biochemical Pharmacology (ISSN: 1873-2968, 0006-2952), 2002 Sep 15; 64(4): 609-616.
Impact Factor: 3.542
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Zell R, Sidigi K, Bucci E, Stelzner A, Goerlach M
* Determinants of the recognition of enteroviral cloverleaf RNA by coxsackievirus B3 proteinase 3C (389 views)
Rna (ISSN: 1355-8382), 2002; 8(2): 188-201.
Impact Factor: 5.099
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Romanelli A, Pedone C, Saviano M, Bianchi N, Borgatti M, Mischiati C, Gambari R
* Molecular interactions between nuclear factor κB (NF-κB) transcription factors and a PNA-DNA chimera mimicking NF-κB binding sites (403 views)
Eur J Biochem (ISSN: 0014-2956, 0014-2956print, 0014-2956linking), 2001 Dec; 268(23): 6066-6075.
Impact Factor: 2.849
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Romanelli A, Pedone C, Saviano M, Bianchi N, Borgatti M, Mischiati C, Gambari R
* Molecular interactions with nuclear factor kappaB (NF-kappaB) transcription factors of a PNA-DNA chimera mimicking NF-kappaB binding sites (409 views)
Eur J Biochem (ISSN: 0014-2956print, 0014-2956linking), 2001 Dec; 268(23): 6066-6075.
Impact Factor: 4.779
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Del Vecchio S, Ciarmiello A, Salvatore M
Clinical imaging of multidrug resistance in cancer (352 views)
Q J Nucl Med (ISSN: 1124-3937, 1125-0135), 1999 Jun; 43(2): 125-131.
Impact Factor: 2.125
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Levchenko A, Mehta B, Spengler BA, Narkar A, Fonti R, Biedler JL, Tsuruo T, Larson SM
Measurement of P-glycoprotein expression in multidrug-resistant human neuroblastoma cell lines using self-competitive binding assay (252 views)
Anal Biochem (ISSN: 0003-2697, 1096-0309electronic, 0003-2697linking), 1996 May 1; 236(2): 338-343.
Impact Factor: 2.017
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Marotta T, Ferrara LA, Di Marino L, Mancini M, Annuzzi G, Russo O, D'Orta G, Lucarelli C, Rossi F
Factors affecting lipoprotein lipase in hypertensive patients (316 views)
Metab Clin Exp (ISSN: 0026-0495, 1532-8600), 1995 Jun; 44(6): 712-718.
Impact Factor: 1.681
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Oliva A, Della Ragione F, Fratta M, Marrone G, Palumbo R, Zappia V
Effect of retinoic acid on osteocalcin gene expression in human osteoblasts (252 views)
Biochem Biophys Res Commun (ISSN: 0006-291xprint, 0006-291xlinking), 1993 Mar 31; 191(3): 908-914.
Impact Factor: 2.671
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Maglione D, Guerriero V, Viglietto G, Ferraro MG, Aprelikova O, Alitalo K, Del Vecchio S, Lei KJ, Chou JY, Persico MG
Two alternative mRNAs coding for the angiogenic factor, placenta growth factor (PlGF), are transcribed from a single gene of chromosome 14 (417 views)
Oncogene (ISSN: 0950-9232, 1476-5594), 1993; 8(4): 925-931.
Impact Factor: 6.772
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Scala S, Pacelli R, Iaffaioli RV, Normanno N, Pepe S, Frasci G, Genua G, Tsuruo T, Tagliaferri P, Bianco AR
Reversal of adriamycin resistance by recombinant α-interferon in multidrug-resistant human colon carcinoma LoVo-doxorubicin cells (553 views)
Cancer Res (ISSN: 0008-5472, 1538-7445, 1538-7445electronic), 1991 Sep 15; 51(18): 4898-4902.
Impact Factor: 8.426
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* Biochemical and Structural Insights into the Winged Helix Domain of P150, the Largest Subunit of the Chromatin Assembly Factor (8 views)
Int J Mol Sci (ISSN: 1422-0067linking), 2022 Feb 15; 23(4): 2160-2160.
Impact Factor: 6.208
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Urbański LJ, Angeli A, Hytönen VP, Di Fiore A, De Simone G, Parkkila S, Supuran CT
* Inhibition of the β-carbonic anhydrase from the protozoan pathogen Trichomonas vaginalis with sulphonamides (138 views)
J Enzym Inhib Med Ch (ISSN: 1475-6366linking, 1475-6374electronic), 2021 Dec; 36(1): 329-334.
Impact Factor: 4.673
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Smaldone G, Caruso D, Sandomenico A, Iaccarino E, Focà A, Ruggiero A, Ruvo M, Vitagliano L
* Members of the GADD45 Protein Family Show Distinct Propensities to form Toxic Amyloid-Like Aggregates in Physiological Conditions (15 views)
Int J Mol Sci (ISSN: 1422-0067linking), 2021 Oct 2; 22 (19 ): N/D-N/D.
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Ngoc B, Vu Hoa T, N , Palumbo R, Rinaldo P, Fagoonee S, Phuc V
* Stem cell-derived exosomes for wound healing: current status and promising directions (53 views)
Minerva Med, 2021 Jun; 112(3): 384-400.
Impact Factor: 4.806
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Di Giovannantonio LG, Acampora D, Omodei D, Nigro V, Barba P, Barbieri E, Chambers I, Simeone A
* Direct repression of Nanog and Oct4 by OTX2 modulates the contribution of epiblast-derived cells to germline and somatic lineage (11 views)
Development (ISSN: 0950-1991linking), 2021 May 15; 148(10): N/D-N/D.
Impact Factor: 5.611
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Grund ME, Choi SJ, Mcnitt DH, Barbier M, Hu G, Lasala PR, Cote CK, Berisio R, Lukomski S
* Burkholderia collagen-like protein 8, Bucl8, is a unique outer membrane component of a putative tetrapartite efflux pump in Burkholderia pseudomallei and Burkholderia mallei (54 views)
Plosone (ISSN: 1932-6203linking, 1932-6203electronic), 2020 Nov 23; 15(11): e0242593-N/D.
Impact Factor: 2.74
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Pelliccia S, Amato J, Capasso D, Di Gaetano S, Massarotti A, Piccolo M, Irace C, Tron GC, Pagano B, Randazzo A, Novellino E, Giustiniano M
* Bio-Inspired Dual-Selective BCL-2/c-MYC G-Quadruplex Binders: Design, Synthesis, and Anticancer Activity of Drug-like Imidazo[2, 1-i]purine Derivatives (89 views)
J Med Chem (ISSN: 0022-2623linking, 0022-2623print), 2020 Mar 12; 63(5): 2035-2050.
Impact Factor: 6.205
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Ala U, Manco M, Mandili G, Tolosano E, Novelli F, Provero P, Altruda F, Fagoonee S
* Proteomics-Based Evidence for a Pro-Oncogenic Role of ESRP1 in Human Colorectal Cancer Cells (119 views)
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Impact Factor: 2.598
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Smaldone G, Beneduce G, Incoronato M, Pane K, Franzese M, Coppola L, Cordella A, Parasole R, Ripaldi M, Nassa G, Soricelli A, Vitagliano L, Mirabelli P, Salvatore M
* KCTD15 is overexpressed in human childhood B-cell acute lymphoid leukemia (78 views)
Sci Rep (ISSN: 2045-2322linking, 2045-2322electronic), 2019 Dec 27; 9(1): 20108-20108.
Impact Factor: 4.122
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Cimmino I, Margheri F, Prisco F, Perruolo G, D'Esposito V, Laurenzana A, Fibbi G, Paciello O, Doti N, Ruvo M, Miele C, Beguinot F, Formisano P, Oriente F
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Faseb J (ISSN: 0892-6638linking), 2019 Oct 15; 33(12): 13893-13904.
Impact Factor: 5.391
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Iaccarino E, Sandomenico A, Corvino G, Foca G, Severino V, Russo R, Caporale A, Raimondo D, D'Abramo M, Alba J, Chambery A, Ruvo M
* Investigating the oxidative refolding mechanism of Cripto-1 CFC domain (297 views)
Int J Biol Macromol (ISSN: 0141-8130linking, 1879-0003electronic), 2019 Sep 15; 137: 1179-1189.
Impact Factor: 4.784
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Russi S, Verma HK, Laurino S, Mazzone P, Storto G, Nardelli A, Zoppoli P, Calice G, La Rocca F, Sgambato A, Lucci V, Falco G, Ruggieri V
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Impact Factor: 4.183
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Pirone L, Caldinelli L, Di Lascio S, Di Girolamo R, Di Gaetano S, Fornasari D, Pollegioni L, Benfante R, Pedone E
* Molecular insights into the role of the polyalanine region in mediating PHOX2B aggregation (278 views) (PDF 52 views)
Febs J (ISSN: 1742-464xlinking), 2019 Apr 7; 286(13): 2505-2521.
Impact Factor: 3.129
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Korotkyi OH, Vovk AA, Dranitsina AS, Falalyeyeva TM, Dvorshchenko KO, Fagoonee S, Ostapchenko LI
* The influence of probiotic diet and chondroitin sulfate administration on Ptgs2, Tgfb1 and Col2a1 expression in rat knee cartilage during monoiodoacetate-induced osteoarthritis (237 views)
Hepatology (ISSN: 0026-4806linking, 1827-1669electronic), 2019 Apr 1; 110(5): 419-424.
Impact Factor: 2.863
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Foca G, Iaccarino E, Foca A, Sanguigno L, Untiveros G, Cuevas-nunez M, Strizzi L, Leonardi A, Ruvo M, Sandomenico A
* Development of conformational antibodies targeting Cripto-1 with neutralizing effects in vitro (519 views)
Biochimie (ISSN: 0300-9084linking, 1638-6183electronic), 2019 Mar; 158: 246-256.
Impact Factor: 3.787
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Tito A, Barbulova A, Zappelli C, Leone M, Ruvo M, Mercurio FA, Chambery A, Russo R, Colucci MG, Apone F
* The Growth Differentiation Factor 11 is Involved in Skin Fibroblast Ageing and is Induced by a Preparation of Peptides and Sugars Derived from Plant Cell Cultures (280 views)
Mol Biotechnol (ISSN: 1073-6085linking, 1559-0305electronic), 2019 Mar; 61 (3 ): 209-220.
Impact Factor: 2.275
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Pirone L, Pitzer JE, D'Abrosca G, Fattorusso R, Malgieri G, Pedone EM, Pedone PV, Roop RM, Baglivo I
* Identifying the region responsible for Brucella abortus MucR higher-order oligomer formation and examining its role in gene regulation (160 views)
Sci Rep (ISSN: 2045-2322electronic, 2045-2322linking), 2018 Nov 22; 8(1): 17238-17238.
Impact Factor: 5.078
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Calvanese L, D'Auria G, Vangone A, Falcigno L, Oliva R
* Structural Basis for Mutations of Human Aquaporins Associated to Genetic Diseases (215 views)
Int J Mol Sc (ISSN: 1422-0067linking, 1422-0067electronic, 1661-6596), 2018 May 25; 19(6): N/D-N/D.
Impact Factor: 3.687
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Ferrucci V, De Antonellis P, Pennino FP, Asadzadeh F, Virgilio A, Montanaro D, Galeone A, Boffa I, Pisano I, Scognamiglio I, Navas L, Diana D, Pedone E, Gargiulo S, Gramanzini M, Brunetti A, Danielson L, Carotenuto M, Liguori L, Verrico A, Quaglietta L, Errico ME, Del Monaco V, D'Argenio V, Tirone F, Mastronuzzi A, Donofrio V, Giangaspero F, Picard D, Remke M, Garzia L, Daniels C, Delattre O, Swartling FJ, Weiss WA, Salvatore F, Fattorusso R, Chesler L, Taylor MD, Cinalli G, Zollo M
* Metastatic group 3 medulloblastoma is driven by PRUNE1 targeting NME1-TGF-beta-OTX2-SNAIL via PTEN inhibition (540 views)
Brain (ISSN: 1460-2156electronic, 0006-8950linking), 2018 May 1; 141(5): 1300-1319.
Impact Factor: 9.915
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Leggio L, Guarino F, Magrì A, Accardi-gheit R, Reina S, Specchia V, Damiano F, Tomasello MF, Tommasino M, Messina A
* Mechanism of translation control of the alternative Drosophila melanogaster Voltage Dependent Anion-selective Channel 1 mRNAs (231 views)
Sci Rep (ISSN: 2045-2322, 2045-2322electronic, 2045-2322linking), 2018 Mar 28; 8(1): 5347-5347.
Impact Factor: 4.259
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Buonanno M, Coppola M, Di Lelio I, Molisso D, Leone M, Pennacchio F, Langella E, Rao R, Monti SM
* Prosystemin, a prohormone that modulates plant defense barriers, is an intrinsically disordered protein (334 views)
Protein Sci (ISSN: 1469-896xelectronic, 0961-8368linking), 2018 Mar; 27(3): 620-632.
Impact Factor: 2.937
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Pelagalli A, Nardelli A, Lucarelli E, Zannetti A, Brunetti A
* Autocrine signals increase Ovine Mesenchymal Stem Cells migration through Aquaporin-1 and CXCR4 overexpression (625 views)
J Cell Physiol (ISSN: 1097-4652electronic, 0021-9541linking), 2018 Jan 18; 233(8): 6241-6249.
Impact Factor: 5.546
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Di Menna L, Joffe ME, Iacovelli L, Orlando R, Lindsley CW, Mairesse J, Gressèns P, Cannella M, Caraci F, Copani A, Bruno V, Battaglia G, Conn PJ, Nicoletti F
* Functional partnership between mGlu3 and mGlu5 metabotropic glutamate receptors in the central nervous system (374 views)
Neuropharm (ISSN: 0028-3908linking, 1873-7064electronic), 2018 Jan; 128: 301-313.
Impact Factor: 3.383
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Deiana M, Mettra B, Martinez-fernandez L, Mazur LM, Pawlik K, Andraud C, Samoc M, Improta R, Monnereau C, Matczyszyn K
* Specific Recognition of G-Quadruplexes Over Duplex-DNA by a Macromolecular NIR Two-Photon Fluorescent Probe (393 views)
J Phys Chem Lett (ISSN: 1948-7185, 1948-7185electronic, 1948-7185linking), 2017 Dec 7; 8(23): 5915-5920.
Impact Factor: 8.709
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Baglivo I, Pirone L, Pedone E, Pitzer JE, Muscariello L, Marino MM, Malgieri G, Freschi A, Chambery A, Roop Ii RM, Pedone PV
* Ml proteins from Mesorhizobium loti and MucR from Brucella abortus: an AT-rich core DNA-target site and oligomerization ability (231 views)
Sci Rep (ISSN: 2045-2322, 2045-2322electronic, 2045-2322linking), 2017 Nov 17; 7(1): 15805-15805.
Impact Factor: 4.122
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Zimbone S, Monaco I, Giani F, Pandini G, Copani AG, Giuffrida ML, Rizzarelli E
* Amyloid Beta monomers regulate cyclic adenosine monophosphate response element binding protein functions by activating type-1 insulin-like growth factor receptors in neuronal cells (705 views) (PDF 195 views)
Aging Cell (ISSN: 1474-9726, 1474-9718linking), 2017 Nov 01; 17(1): N/D-N/D.
Impact Factor: 7.627
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Santagata S, Portella L, Napolitano M, Greco A, D'Alterio C, Barone MV, Luciano A, Gramanzini M, Auletta L, Arra C, Zannetti A, Scala S
* A novel CXCR4-targeted near-infrared (NIR) fluorescent probe (Peptide R-NIR750) specifically detects CXCR4 expressing tumors (359 views) (PDF 203 views)
Sci Rep (ISSN: 2045-2322, 2045-2322electronic, 2045-2322linking), 2017 May 31; 7(1): 2554-2554.
Impact Factor: 4.122
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Fagoonee S, Picco G, Orso F, Arrigoni A, Longo DL, Forni M, Scarfo I, Cassenti A, Piva R, Cassoni P, Silengo L, Tolosano E, Aime S, Taverna D, Pandolfi PP, Brancaccio M, Medico E, Altruda F
* The RNA-binding protein ESRP1 promotes human colorectal cancer progression (338 views)
Oncotarget (ISSN: 1949-2553electronic, 1949-2553linking), 2016 Dec 28; 8(6): 10007-10024.
Impact Factor: 5.168
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Majkowska-skrobek G, Latka A, Berisio R, Maciejewska B, Squeglia F, RomanoM, Lavigne R, Struve C, Drulis-kawa Z
* Capsule-Targeting Depolymerase, Derived from Klebsiella KP36 Phage, as a Tool for the Development of Anti-Virulent Strategy (339 views)
Viruses-Basel (ISSN: 1999-4915), 2016 Dec 1; 8(12): N/D-N/D.
Impact Factor: 3.465
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Magri A, Di Rosa MC, Tomasello MF, Guarino F, Reina S, Messina A, De Pinto V
* Overexpression of human SOD1 in VDAC1-less yeast restores mitochondrial functionality modulating beta-barrel outer membrane protein genes (341 views)
Bba-Gen Subjects (ISSN: 0005-2728, 0006-3002print, 1570-9639print), 2016 Mar 4; 1857(6): 789-798.
Impact Factor: 4.932
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Gargiulo S, Anzilotti S, Coda AR, Gramanzini M, Greco A, Panico M, Vinciguerra A, Zannetti A, Vicidomini C, Dolle F, Pignataro G, Quarantelli M, Annunziato L, Brunetti A, Salvatore M, Pappata S
* Imaging of brain TSPO expression in a mouse model of amyotrophic lateral sclerosis with (18)F-DPA-714 and micro-PET/CT (773 views) (PDF 297 views)
Eur J Nucl Med (ISSN: 1619-7070, 1619-7089, 1619-7070print), 2016 Jan 27; 43(7): 1348-1359.
Impact Factor: 7.277
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Foca A, Sanguigno L, Foca G, Strizzi L, Iannitti R, Palumbo R, Hendrix MJ, Leonardi A, Ruvo M, Sandomenico A
* New Anti-Nodal Monoclonal Antibodies Targeting the Nodal Pre-Helix Loop Involved in Cripto-1 Binding (667 views) (PDF 261 views)
Int J Mol Sc (ISSN: 1422-0067, 1661-6596, 1422-0067linking), 2015 Sep 7; 16(9): 21342-21362.
Impact Factor: 3.257
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Cipolletta E, Rusciano MR, Maione AS, Santulli G, Sorriento D, Del Giudice C, Ciccarelli M, Franco A, Crola C, Campiglia P, Sala M, Gomez-Monterrey I, De Luca N, Trimarco B, Iaccarino G, Illario M
* Targeting the CaMKII/ERK Interaction in the Heart Prevents Cardiac Hypertrophy (260 views)
Plosone (ISSN: 1932-6203, 1932-6203electronic, 1932-6203linking), 2015 Jun 25; 10(6): e0130477-e0130477.
Impact Factor: 3.057
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Kim YH, Shin SW, Pellicano R, Fagoonee S, Choi IJ, Kim YI, Park B, Choi JM, Kim SG, Choi J, Park JY, Oh S, Yang HJ, Lim JH, Im JP, Kim JS, Jung HC, Ponzetto A, Figura N, Malfertheiner P, Choi IJ, Kook MC, Kim YI, Cho SJ, Lee JY, Kim CG, Park B, Nam BH, Bae SE, Choi KD, Choe J, Kim SO, Na HK, Choi JY, Ahn JY, Jung KW, Lee J, Kim DH, Chang HS, Song HJ, Lee GH, Jung HY, Seta T, Takahashi Y, Noguchi Y, Shikata S, Sakai T, Sakai K, Yamashita Y, Nakayama T, Leja M, Park JY, Murillo R, Liepniece-karele I, Isajevs S, Kikuste I, Rudzite D, Krike P, Parshutin S, Polaka I, Kirsners A, Santare D, Folkmanis V, Daugule I, Plummer M, Herrero R, Tsukamoto T, Nakagawa M, Kiriyama Y, Toyoda T, Cao X, Corral JE, Mera R, Dye CW, Morgan DR, Lee YC, Lin JT, Garcia Martin R, Matia Cubillo A, Lee SH, Park JM, Han YM, Ko WJ, Hahm KB, Leontiadis GI, Ford AC, Ichinose M, Sugano K, Jeong M, Park JM, Han YM, Park KY, Lee DH, Yoo JH, Cho JY, Hahm KB, Bang CS, Baik GH, Shin IS, Kim JB, Suk KT, Yoon JH, Kim YS, Kim DJ
* Helicobacter pylori Eradication for Prevention of Metachronous Recurrence after Endoscopic Resection of Early Gastric Cancer (282 views)
N Engl J Med (ISSN: 0028-4793, 0028-4793linking, 1533-4406electronic), 2015 Jun; 30642104201566393291: 749-756.
Impact Factor: 59.558
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Giacomelli C, Trincavelli ML, Satriano C, Hansson O, La Mendola D, Rizzarelli E, Martini C
* Copper (II) ions modulate Angiogenin activity in human endothelial cells (404 views)
Int J Biochem Cell B (ISSN: 1357-2725), 2015 Mar; 60: 185-196.
Impact Factor: 3.905
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Antonini D, Sirico A, Aberdam E, Ambrosio R, Campanile C, Fagoonee S, Altruda F, Aberdam D, Brissette JL, Missero C
* A composite enhancer regulates p63 gene expression in epidermal morphogenesis and in keratinocyte differentiation by multiple mechanisms (812 views)
Nucleic Acids Res (ISSN: 0305-1048, 1362-4962), 2015 Jan; 43(2): 862-874.
Impact Factor: 9.202
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Neve Polimeno M, Ierano C, D'Alterio C, Simona Losito N, Napolitano M, Portella L, Scognamiglio G, Tatangelo F, Maria Trotta A, Curley S, Costantini S, Liuzzi R, Izzo F, Scala S
* CXCR4 expression affects overall survival of HCC patients whereas CXCR7 expression does not (523 views)
Cell Mol Immunol (ISSN: 1672-7681), 2014 Nov 3; 12(4): 474-482.
Impact Factor: 4.112
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Forzati F, Federico A, Pallante P, Colamaio M, Esposito F, Sepe R, Gargiulo S, Luciano A, Arra C, Palma G, Bon G, Bucher S, Falcioni R, Brunetti A, Battista S, Fedele M, Fusco A
* CBX7 gene expression plays a negative role in adipocyte cell growth and differentiation (252 views)
Biol Open (ISSN: 2046-6390), 2014 Sep 15; 3(9): 871-879.
Impact Factor: 2.416
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Gargiulo S, Petretta MP, Greco A, Panico M, Larobina M, Gramanzini M, Schiattarella GG, Esposito G, Petretta M, Brunetti A, Cuocolo A
* Genetic deletion in uncoupling protein 3 augments 18F-fluorodeoxyglucose cardiac uptake in the ischemic heart (429 views)
Bmc Cardiovasc Disor (ISSN: 1471-2261), 2014 Sep 8; 14(1): 98-98.
Impact Factor: 1.878
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Antoniali G, Lirussi L, D'Ambrosio C, Dal Piaz F, Vascotto C, Casarano E, Marasco D, Scaloni A, Fogolari F, Tell G
* SIRT1 gene expression upon genotoxic damage is regulated by APE1 through nCaRE-promoter elements (503 views)
Mol Biol Cell (ISSN: 1059-1524), 2014 Feb 15; 25(4): 532-547.
Impact Factor: 4.466
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De Chiara L, Fagoonee S, Ranghino A, Bruno S, Camussi G, Tolosano E, Silengo L, Altruda F
* Renal cells from spermatogonial germline stem cells protect against kidney injury (326 views)
J Am Soc Nephrol (ISSN: 1046-6673), 2014 Feb; 25(2): 316-328.
Impact Factor: 9.343
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D'Ambrosio K, Lopez M, Dathan NA, Ouahrani-bettache S, Köhler S, Ascione G, Monti SM, Winum JY, De Simone G
* Structural basis for the rational design of new anti-Brucella agents: The crystal structure of the C366S mutant of l-histidinol dehydrogenase from Brucella suis (421 views)
Biochimie (ISSN: 0300-9084, 1638-6183, 0300-9084linking), 2014 Feb; 97(1): 114-120.
Impact Factor: 2.963
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Doti N, Reuther C, Scognamiglio PL, Dolga AM, Plesnila N, Ruvo M, Culmsee C
* Inhibition of the AIF/CypA complex protects against intrinsic death pathways induced by oxidative stress (532 views)
Cell Death & (ISSN: 2041-4889, 2041-4889electronic), 2014 Jan 16; 5(1): e993-e993.
Impact Factor: 5.014
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Contursi P, Farina B, Pirone L, Fusco S, Russo L, Bartolucci S, Fattorusso R, Pedone E
* Structural and functional studies of Stf76 from the Sulfolobus islandicus plasmid-virus pSSVx: a novel peculiar member of the winged helix-turn-helix transcription factor family (359 views)
Nucleic Acids Res (ISSN: 0305-1048, 1362-4962), 2014; 42(9): 5993-6011.
Impact Factor: 9.112
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Bergamo P, Cocca E, Palumbo R, Gogliettino M, Rossi M, Palmieri G
* RedOx status, proteasome and APEH: Insights into anticancer mechanisms of t10, c12-conjugated linoleic acid isomer on A375 melanoma cells (693 views)
Plosone (ISSN: 1932-6203, 1932-6203electronic, 1932-6203linking), 2013 Nov 19; 8(11): N/D-N/D.
Impact Factor: 3.534
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Del Giudice I, Limauro D, Pedone E, Bartolucci S, Fiorentino G
* A novel arsenate reductase from the bacterium Thermus thermophilus HB27: Its role in arsenic detoxification (377 views)
Bba-Gen Subjects (ISSN: 1570-9639, 0006-3002, 0925-4439), 2013 Oct; 1834(10): 2071-2079.
Impact Factor: 3.191
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Squeglia F, Bachert B, Romano M, Lukomski S, Berisio R
* Crystallization and preliminary X-ray crystallographic analysis of the variable domain of Scl2. 3, a streptococcal collagen-like protein from invasive M3-type Streptococcus pyogenes (346 views)
Nucleosides Nucleotides Nucleic Acids (ISSN: 1744-3091, 1744-4309), 2013 Sep; 69(9): 1023-1025.
Impact Factor: 0.568
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Farina B, Doti N, Pirone L, Malgieri G, Pedone E, Ruvo M, Fattorusso R
* Molecular basis of the PED/PEA15 interaction with the C-terminal fragment of phospholipase D1 revealed by NMR spectroscopy (445 views)
Bba-Gen Subjects (ISSN: 1570-9639, 0006-3002, 0925-4439), 2013 Sep; 1834(8): 1572-1580.
Impact Factor: 3.191
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Nande R, Greco A, Gossman MS, Lopez JP, Claudio L, Salvatore M, Brunetti A, Denvir J, Howard CM, Claudio PP
* Microbubble-assisted p53, RB, and p130 gene transfer in combination with radiation therapy in prostate cancer (436 views)
Current Gene Therapy (ISSN: 1875-5631, 1566-5232), 2013 Jun 1; 13(3): 163-174.
Impact Factor: 4.906
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Lombardo B, Rocco T, Esposito MT, Cantilena B, Gargiulo S, Greco A, Montanaro D, Brunetti A, Pastore L
* Thymidine Kinase-Mediated Shut Down of Bone Morphogenetic Protein-4 Expression Allows Regulated Bone Production (328 views)
Current Gene Therapy (ISSN: 1566-5232, 1875-5631), 2013 Jun 1; 13(3): 202-210.
Impact Factor: 4.906
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Romano S, Staibano S, Greco A, Brunetti A, Nappo G, Ilardi G, Martinelli R, Sorrentino A, Di Pace A, Mascolo M, Bisogni R, Scalvenzi M, Alfano B, Romano M
* FK506 binding protein 51 positively regulates melanoma stemness and metastatic potential (413 views) (PDF 240 views)
Cell Death & (ISSN: 2041-4889, 2041-4889electronic), 2013 Apr 4; 4(6): e578-e578.
Impact Factor: 5.333
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Carotenuto M, Pedone E, Diana D, de Antonellis P, Džeroski S, Marino N, Navas L, Di Dato V, Scoppettuolo MN, Cimmino F, Correale S, Pirone L, Monti SM, Bruder E, Zenko B, Slavkov I, Pastorino F, Ponzoni M, Schulte JH, Schramm A, Eggert A, Westermann F, Arrigoni G, Accordi B, Basso G, Saviano M, Fattorusso R, Zollo M
* Neuroblastoma tumorigenesis is regulated through the Nm23-H1/h-Prune C-terminal interaction (470 views)
Sci Rep (ISSN: 2045-2322, 2045-2322electronic, 2045-2322linking), 2013 Mar 1; 3: 1351-1351.
Impact Factor: 5.078
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D'Angelo D, Borbone E, Palmieri D, Uboldi S, Esposito F, Frapolli R, Pacelli R, D'Incalci M, Fusco A
* The impairment of the High Mobility Group A (HMGA) protein function contributes to the anticancer activity of trabectedin (388 views)
European Journal Of Cancer (ISSN: 0959-8049), 2013 Mar; 49(5): 1142-1151.
Impact Factor: 4.819
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Rosa R, Marciano R, Malapelle U, Formisano L, Nappi L, D'Amato C, D'Amato V, Damiano V, Marf G, Del Vecchio S, Zannetti A, Greco A, De Stefano A, Carlomagno C, Veneziani BM, Troncone G, De Placido S, Bianco R
* Sphingosine Kinase 1 Overexpression Contributes to Cetuximab Resistance in Human Colorectal Cancer Models (630 views)
Clin Cancer Res (ISSN: 1078-0432, 1078-0432linking, 1078-0432print), 2013 Jan 1; 19(1): 138-147.
Impact Factor: 8.193
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Buanne P, Renzone G, Monteleone F, Vitale M, Monti SM, Sandomenico A, Garbi C, Montanaro D, Accardo M, Troncone G, Zatovicova M, Csaderova L, Supuran CT, Pastorekova S, Scaloni A, De Simone G, Zambrano N
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J Proteome Res (ISSN: 1535-3893), 2013 Jan; 12(1): 282-292.
Impact Factor: 5.001
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Costa B, Bendinelli S, Gabelloni P, Da Pozzo E, Daniele S, Scatena F, Vanacore R, Campiglia P, Bertamino A, Gomez-Monterrey I, Sorriento D, Del Giudice C, Iaccarino G, Novellino E, Martini C
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Impact Factor: 3.534
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Sorriento D, Fusco A, Ciccarelli M, Rungi A, Anastasio A, Carillo A, Dorn II GW, Trimarco B, Iaccarino G
* Mitochondrial G protein coupled receptor kinase 2 regulates proinflammatory responses in macrophages (368 views)
Febs Lett (ISSN: 0014-5793, 0014-5793print, 1873-3468electronic), 2013; 587(21): 3487-3494.
Impact Factor: 3.341
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Berisio R
* Learning from pathogens: Exploiting host-pathogen liaison for therapeutic development (365 views)
Curr Protein Pept Sci (ISSN: 1389-2037, 1389-2037linking), 2012 Dec; 13(8): 697-698.
Impact Factor: 2.326
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Forestier A, Douki T, Sauvaigo S, De Rosa V, Demeilliers C, Rachidi W
* Alzheimer's disease-associated neurotoxic peptide amyloid-beta impairs base excision repair in human neuroblastoma cells (441 views)
Int J Mol Sc (ISSN: 1422-0067linking, 1422-0067electronic, 1661-6596), 2012 Nov 13; 13(11): 14766-14787.
Impact Factor: 2.464
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Sorriento D, Illario M, Finelli R, Iaccarino G
* To NFkappaB or not to NFkappaB: The Dilemma on How to Inhibit a Cancer Cell Fate Regulator (246 views)
Transl Med Unisa (ISSN: 2239-9747electronic, 2239-9747linking), 2012 Oct 11; 4: 73-85.
Impact Factor: 2.256
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Finetti F, Basile A, Capasso D, Di Gaetano S, Di Stasi R, Pascale M, Turco CM, Ziche M, Morbidelli L, D'Andrea LD
* Functional and pharmacological characterization of a VEGF mimetic peptide on reparative angiogenesis (562 views)
Biochem Pharmacol Biochemical Pharmacology (ISSN: 0006-2952, 1873-2968), 2012 Sep 1; 84(3): 303-311.
Impact Factor: 4.576
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Riccio A, Cubellis MV
* Gain of function in CDKN1C (495 views)
Nature Genetics (ISSN: 1061-4036), 2012 Jul; 44(7): 737-738.
Impact Factor: 35.209
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Pedicini P, Caivano R, Jereczek-Fossa BA, Strigari L, Vischioni B, Alterio D, Cremonesi M, Botta F, Nappi A, Improta G, Storto G, Benassi M, Orecchia R
* Modelling the correlation between EGFr expression and tumour cell radiosensitivity, and combined treatments of radiation and monoclonal antibody EGFr inhibitors (364 views)
Theor Biol Med Model (ISSN: 1742-4682), 2012 Jun 19; 9(1): 23-23.
Impact Factor: 1.461
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Avitabile C, Moggio L, Malgieri G, Capasso D, Di Gaetano S, Saviano M, Pedone C, Romanelli A
* Gamma Sulphate Pna (pna S): Highly Selective Dna Binding Molecule Showing Promising Antigene Activity (425 views)
Plosone (ISSN: 1932-6203, 1932-6203electronic, 1932-6203linking), 2012 May 7; 7(5): e35774-e35774.
Impact Factor: 3.73
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Calafiore M, Copani A, Deng W
* DNA polymerase-β mediates the neurogenic effect of β-amyloid protein in cultured subventricular zone neurospheres (557 views)
Journal Of Neuroscience Research (ISSN: 0360-4012), 2012 Mar; 90(3): 559-567.
Impact Factor: 2.974
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Langlois C, Del Gatto A, Arseneault G, Lafrance-vanasse J, De Simone M, Morse T, De Paola I, Lussier-price M, Legault P, Pedone C, Zaccaro L, Omichinski JG
* Structure-based design of a potent artificial transactivation domain based on p53 (398 views)
J Am Chem Soc (ISSN: 1520-5126, 0002-2786, 0002-7863), 2012 Jan 25; 134(3): 1715-1723.
Impact Factor: 5.65
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Caraci F, Spampinato S, Sortino MA, Bosco P, Battaglia G, Bruno V, Drago F, Nicoletti F, Copani A
* Dysfunction of TGF-β1 signaling in Alzheimer's disease: Perspectives for neuroprotection (819 views)
Cell Tissue Res (ISSN: 0302-766x), 2012 Jan; 347(1): 291-301.
Impact Factor: 3.677
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Gargiulo S, Greco A, Gramanzini M, Petretta MP, Ferro A, Larobina M, Panico M, Brunetti A, Cuocolo A
* PET/CT imaging in mouse models of myocardial ischemia (647 views)
J Biomed Biotechnol (ISSN: 1110-7251, 1110-7243), 2012; 2012: 541872-541872.
Impact Factor: 2.88
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Viparelli F, Doti N, Sandomenico A, Marasco D, Dathan NA, Miele C, Beguinot F, Monti SM, Ruvo M
* GSM48878: CD8 IL2-D2 (378 views)
Gene Expression Omnibus, 2011 Dec 2; 59(2): 302-308.
Impact Factor: 2.082
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Di Paola R, Impellizzeri D, Salinaro AT, Mazzon E, Bellia F, Cavallaro M, Cornelius C, Vecchio G, Calabrese V, Rizzarelli E, Cuzzocrea S
* Administration of carnosine in the treatment of acute spinal cord injury (562 views)
Biochem Pharmacol Biochemical Pharmacology (ISSN: 1873-2968, 0006-2952), 2011 Nov 15; 82(10): 1478-1489.
Impact Factor: 4.705
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Malgieri G, Zaccaro L, Leone M, Bucci E, Esposito S, Baglivo I, Del Gatto A, Russo L, Scandurra R, Pedone PV, Fattorusso R, Isernia C
* Zinc to Cadmium Replacement in the A. thaliana SUPERMAN Cys(2)His(2) Zinc Finger Induces Structural Rearrangements of Typical DNA Base Determinant Positions (423 views)
Biopolymers (ISSN: 0006-3525, 0006-6352, 0006-3525print), 2011 Nov; 95(11): 801-810.
Impact Factor: 2.87
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Palmieri D, Valentino T, D'Angelo D, De Martino I, Postiglione I, Pacelli R, Croce CM, Fedele M, Fusco A
* HMGA proteins promote ATM expression and enhance cancer cell resistance to genotoxic agents (765 views)
Oncogene (ISSN: 0950-9232, 1476-5594), 2011 Jul 7; 30(27): 3024-3035.
Impact Factor: 6.373
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Scognamiglio PL, Doti N, Grieco P, Pedone C, Ruvo M, Marasco D
* Discovery Of Small Peptide Antagonists Of Ped/Pea15-D4alpha Interaction From Simplified Combinatorial Libraries (447 views)
Chem Biol Drug Des (ISSN: 1747-0277, 1747-0285), 2011 May; 77(5): 319-327.
Impact Factor: 2.282
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Caraci F, Molinaro G, Battaglia G, Giuffrida ML, Riozzi B, Traficante A, Bruno V, Cannella M, Merlo S, Wang X, Heinz BA, Nisenbaum ES, Britton TC, Drago F, Sortino MA, Copani A, Nicoletti F
* Targeting group II Metabotropic Glutamate (mGlu) receptors for the treatment of psychosis associated with alzheimer's disease: Selective activation of mGlu2 receptors amplifies β-amyloid toxicity in cultured neurons, whereas dual activation of mGlu2 and mGlu3 receptors is neuroprotective (715 views)
Mol Pharmacol (ISSN: 0026-895x), 2011 Mar; 79(3): 618-626.
Impact Factor: 4.883
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Pizzo E, Merlino A, Turano M, Russo Krauss I, Coscia F, Zanfardino A, Varcamonti M, Furia A, Giancola C, Mazzarella L, Sica F, D'Alessio G
* A new RNase sheds light on the RNase/angiogenin subfamily from zebrafish (741 views)
Biochem J (ISSN: 1470-8728electronic, 0264-6021linking, 0264-6021print), 2011 Jan 15; 433(2): 345-355.
Impact Factor: 4.897
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Ruggiero A, Squeglia F, Pirone L, Correale S, Berisio R
* Expression, purification, crystallization and preliminary X-ray crystallographic analysis of a major fragment of the resuscitation-promoting factor RpfB from Mycobacterium tuberculosis (374 views)
Nucleosides Nucleotides Nucleic Acids (ISSN: 1744-3091, 1744-4309), 2011 Jan 1; 67(1): 164-168.
Impact Factor: 0.506
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Ciccarelli M, Sorriento D, Cipolletta E, Santulli G, Fusco A, Zhou R-H, Eckhart AD, Peppel K, Koch WJ, Trimarco B, Iaccarino G
* Impaired neoangiogenesis in β2-adrenoceptor gene-deficient mice: Restoration by intravascular human β2-adrenoceptor gene transfer and role of NFkB and CREB transcription factors (352 views)
Br J Pharmacol British Journal Of Pharmacology (ISSN: 0007-1188), 2011; 162(3): 712-721.
Impact Factor: 4.409
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Spina-Purrello V, Giliberto S, Barresi V, Nicoletti VG, Giuffrida Stella AM, Rizzarelli E
* Modulation of PARP-1 and PARP-2 expression by L-carnosine and trehalose after LPS and INFγ-induced oxidative stress (420 views)
Neurochemical Research (ISSN: 0364-3190, 1573-6903), 2010 Dec; 35(12): 2144-2153.
Impact Factor: 2.608
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Amorosi S, Vigliano I, Del Giudice E, Panico L, Maruotti GM, Fusco A, Quarantelli M, Ciccone C, Ursini MV, Martinelli P, Pignata C
* Brain alteration in a Nude/SCID fetus carrying FOXN1 homozygous mutation (393 views)
J Neurol Sci (ISSN: 0022-510x), 2010 Nov 15; 298(1-2): 121-123.
Impact Factor: 2.167
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Calvanese L, Marasco D, Doti N, Saporito A, D'Auria G, Paolillo L, Ruvo M, Falcigno L
* Structural Investigations on the Nodal-Cripto Binding: A Theoretical and Experimental Approach (485 views)
Biopolymers (ISSN: 0006-3525, 0006-6352, 0006-3525print), 2010 Nov; 93(11): 1011-1021.
Impact Factor: 2.572
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Farina B, Pirone L, Russo L, Viparelli F, Doti N, Pedone C, Pedone E, Fattorusso R
* NMR backbone dynamics studies of human PED/PEA-15 outline protein functional sites (641 views)
Febs J (ISSN: 1742-4658, 1742-464x, 1742-4658electronic), 2010 Oct; 277(20): 4229-4240.
Impact Factor: 3.129
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Doti N, Cassese A, Marasco D, Paturzo F, Sabatella M, Viparelli F, Dathan N, Monti SM, Miele C, Formisano P, Beguinot F, Ruvo M
* Residues 762-801 of PLD1 mediate the interaction with PED/PEA15 (457 views)
Mol Biosyst (ISSN: 1742-206x), 2010 Oct; 6(10): 2039-2048.
Impact Factor: 3.825
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Alterio V, Aurilia V, Romanelli A, Parracino A, Saviano M, D'Auria S, De Simone G
* Crystal structure of an S-formylglutathione hydrolase from pseudoalteromonas haloplanktis TAC125 (354 views)
Biopolymers (ISSN: 0006-3525, 0006-6352, 0006-3525print), 2010 Sep; 93(8): 669-677.
Impact Factor: 2.572
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Pensato S, Saviano M, Bianchi N, Borgatti M, Fabbri E, Gambari R, Romanelli A
* Gamma-Hydroxymethyl Pnas: Synthesis, Interaction With Dna And Inhibition Of Protein/Dna Interactions (350 views)
Bioorg Chem, 2010 Sep; 38(5): 196-201.
Impact Factor: 2.141
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Bombardieri E, Ambrosini V, Aktolun C, Baum RP, Bishof-delaloye A, Del Vecchio S, Maffioli L, Mortelmans L, Oyen W, Pepe G, Chiti A
* In-111-pentetreotide scintigraphy: procedure guidelines for tumour imaging (467 views)
Eur J Nucl Med (ISSN: 1619-7070, 1619-7089, 0340-6997), 2010 Jul; 37(7): 1441-1448.
Impact Factor: 5.036
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Pensato S, Renda M, Leccia F, Saviano M, D'Andrea LD, Pedone C, Pedone PV, Romanelli A
* PNA zipper as a dimerization tool: development of a bZip mimic (477 views)
Biopolymers (ISSN: 0006-3525, 0006-6352, 0006-3525print), 2010 May; 93(5): 434-441.
Impact Factor: 2.572
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Canettieri G, Di Marcotullio L, Greco A, Coni S, Antonucci L, Infante P, Pietrosanti L, De Smaele E, Ferretti E, Miele E, Pelloni M, De Simone G, Pedone E, Gallinari P, Giorgi A, Steinkuhler C, Vitagliano L, Pedone C, Schinin ME, Screpanti I, Gulino A
* Histone deacetylase and Cullin3-REN(KCTD11) ubiquitin ligase interplay regulates Hedgehog signalling through Gli acetylation (575 views)
Nature Cell Biol Nature Cell Biology (ISSN: 1476-4679, 1465-7392), 2010 Feb; 12(2): 132-142.
Impact Factor: 19.407
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Orsi S, De Capua A, Guarnieri D, Marasco D, Netti PA
* Cell recruitment and transfection in gene activated collagen matrix (371 views)
Biomaterials (ISSN: 0142-9612, 1878-5905electronic, 0142-9612linking), 2010 Jan; 31(3): 570-576.
Impact Factor: 7.883
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Sorriento D, Santulli G, Fusco A, Anastasio A, Trimarco B, Iaccarino G
* Intracardiac injection of AdGRK5-NT reduces left ventricular hypertrophy by inhibiting NF-κB-Dependent hypertrophic gene expression (378 views)
Hypertensionhypertension (ISSN: 0194-911x), 2010; 56(4): 696-704.
Impact Factor: 6.908
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Galasso G, De Rosa R, Piscione F, Iaccarino G, Vosa C, Sorriento D, Piccolo R, Rapacciuolo A, Walsh K, Chiariello M
* Myocardial expression of FOXO3a-Atrogin-1 pathway in human heart failure (246 views)
Eur J Heart Fail European Journal Of Heart Failure (ISSN: 1388-9842), 2010; 12(12): 1290-1296.
Impact Factor: 4.512
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D'Antò V, Michelotti A, Esposito L, Zagari A, Liguori R, Sacchetti L
* Nonsynonimous mutation of catechol-O-methyl-transferase (COMT) gene in a patient with temporomandibular disorder (332 views)
J Sci Med Sport (ISSN: 1440-2440), 2010; 13(6): 174-179.
Impact Factor: 3.194
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Calabrese V, Cornelius C, Rizzarelli E, Owen JB, Dinkova-Kostova AT, Butterfield DA
* Nitric oxide in cell survival: a janus molecule (593 views)
Antioxid Redox Signal (ISSN: 1557-7716, 1523-0864, 1523-0864linking), 2009 Nov; 11(11): 2717-2739.
Impact Factor: 7.581
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Marasco D, Stilo R, Sandomenico A, Monti SM, Tizzano B, De Capua A, Varricchio E, Liguoro D, Zotti T, Formisano S, Ruvo M, Vito P
* Generation And Functional Characterization Of A Bcl10-Inhibitory Peptide That Represses Nf-Kappa B Activation (379 views)
Biochem J (ISSN: 0264-6021, 1470-8728electronic, 0264-6021linking), 2009 Sep 15; 422(3): 553-561.
Impact Factor: 5.155
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D'Andrea LD, Del Gatto A, De Rosa L, Romanelli A, Pedone C
* Peptides targeting angiogenesis related growth factor receptors (14425 views)
Curr Pharm Des Current Pharmaceutical Design (ISSN: 1873-4286, 1381-6128), 2009 Jul; 15(21): 2414-2429.
Impact Factor: 4.414
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Sandomenico A, Monti SM, Sabatella M, De Capua A, Tornatore L, Doti N, Viparelli F, Dathan NA, Pedone C, Ruvo M, Marasco D
* Protein-protein interactions: a simple strategy to identify binding sites and peptide antagonists (439 views)
Chem Biol Drug Des (ISSN: 1747-0285, 1747-0277), 2009 May; 73(5): 483-493.
Impact Factor: 2.473
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Ierano C, Giuliano P, D'Alterio C, Cioffi M, Mettivier V, Portella L, Napolitano M, Barbieri A, Arra C, Liguori G, Franco R, Palmieri G, Rozzo C, Pacelli R, Castello G, Scala S
* A point mutation (G574A) in the chemokine receptor CXCR4 detected in human cancer cells enhances migration (375 views)
Cell Cycle (ISSN: 1538-4101), 2009 Apr 15; 8(8): 1228-1237.
Impact Factor: 4.087
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Garzia L, Andolfo I, Cusanelli E, Marino N, Petrosino G, De Martino D, Esposito V, Galeone A, Navas L, Esposito S, Gargiulo S, Fattet S, Donofrio V, Cinalli G, Brunetti A, Del Vecchio L, Northcott PA, Delattre O, Taylor MD, Iolascon A, Zollo M
* MicroRNA-199b-5p Impairs Cancer Stem Cells through Negative Regulation of HES1 in Medulloblastoma (426 views)
Plosone (ISSN: 1932-6203, 1932-6203electronic, 1932-6203linking), 2009 Mar 24; 4(3): e4998-e4998.
Impact Factor: 4.351
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Calvanese L, Saporito A, Oliva R, D'Auria G, Pedone C, Paolillo L, Ruvo M, Marasco D, Falcigno L
* Structural insights into the interaction between the Cripto CFC domain and the ALK4 receptor (443 views)
J Pept Sci (ISSN: 1075-2617, 1099-1387, 1075-2617print), 2009 Mar; 15(3): 175-183.
Impact Factor: 1.807
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Francalanci F, Avolio M, De Luca E, Longo DL, Menchise V, Guazzi P, Sgro F, Marino M, Goitre L, Balzac F, Trabalzini L, Retta SF
* Structural and functional differences between KRIT1A and KRIT1B isoforms: A framework for understanding CCM pathogenesis (485 views)
Exp Cell Res (ISSN: 0014-4827), 2009 Jan 15; 315(2): 285-303.
Impact Factor: 3.589
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Sorriento D, Campanile A, Santulli G, Leggiero E, Pastore L, Trimarco B, Iaccarino G
* A new synthetic protein, TAT-RH, inhibits tumor growth through the regulation of NFκB activity (341 views)
Mol Cancermolecular Cancer (ISSN: 1476-4598), 2009; 8: N/D-N/D.
Impact Factor: 4.16
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Arpaia P, Clemente F, Manna C, Montenero G
* Automatic modeling based on cultural programming for osseointegration diagnosis (275 views)
Vols 1 3i2mtc (ISSN: 1091-5281), 2009; N/D: 1278-1283.
Impact Factor: 0
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Lucignani G, Salvatore M
* Biotechnology in molecular and cellular imaging (262 views)
Minerva Biotecnol (ISSN: 1120-4826), 2009; 21(1): 1-3.
Impact Factor: 0.268
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Ponticelli S, Marasco D, Tarallo V, Albuquerque RJC, Mitola S, Takeda A, Stassen J, Presta M, Ambati J, Ruvo M, De Falco S
* Modulation of Angiogenesis by a Tetrameric Tripeptide That Antagonizes Vascular Endothelial Growth Factor Receptor (465 views)
Jbc Papers (ISSN: 0021-9258, 1083-351x, 0021-9258linking), 2008 Dec 5; 283(49): 34250-34259.
Impact Factor: 5.52
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Caraci F, Busceti C, Biagioni F, Aronica E, Mastroiacovo F, Cappuccio I, Battaglia G, Bruno V, Caricasole A, Copani A, Nicoletti
* The Wnt antagonist, Dickkopf-1, as a target for the treatment of neurodegenerative disorders (362 views)
Neurochemical Research (ISSN: 0364-3190, 1573-6903), 2008 Dec; 33(12): 2401-2406.
Impact Factor: 2.26
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Galdiero S, Falanga A, Vitiello M, Raiola L, Fattorusso R, Browne H, Pedone C, Isernia C, Galdiero M
* Analysis of a membrane interacting region of herpes simplex virus type 1 glycoprotein (538 views)
Jbc Papers (ISSN: 0021-9258, 1083-351x, 0021-9258linking), 2008 Oct 31; 283(44): 29993-30009.
Impact Factor: 5.52
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Castiglione M, Calafiore M, Costa L, Sortino MA, Nicoletti F, Copani A
* Group I metabotropic glutamate receptors control proliferation, survival and differentiation of cultured neural progenitor cells isolated from the subventricular zone of adult mice (416 views)
Neuropharm (ISSN: 0028-3908, 1873-7064electronic, 0028-3908linking), 2008 Sep; 55(4): 560-567.
Impact Factor: 3.383
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Viparelli F, Doti N, Sandomenico A, Marasco D, Dathan NA, Miele C, Beguinot F, Monti SM, Ruvo M
* Expression and purification of the D4 region of PLD1 and characterization of its interaction with PED-PEA15 (421 views)
Protein Expr Purif (ISSN: 1046-5928), 2008 Jun; 59(2): 302-308.
Impact Factor: 1.621
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Sbardella G, Castellano S, Vicidomini C, Rotili D, Nebbioso A, Miceli M, Altucci L, Mai A
* Identification of long chain alkylidenemalonates as novel small molecule modulators of histone acetyltransferases (285 views)
Bioorganic & Medicinal Chemistry Letters (ISSN: 0960-894x), 2008 May 1; 18(9): 2788-2792.
Impact Factor: 2.531
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Limauro D, Pedone E, Galdi I, Bartolucci S
* Peroxiredoxins as cellular guardians in Sulfolobus solfataricus - characterization of Bcp1, Bcp3 and Bcp4 (354 views)
Febs Journal (ISSN: 1742-464x), 2008 May; 275(9): 2067-2077.
Impact Factor: 3.139
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Goldfine ID, Maddux BA, Youngren JF, Reaven G, Accili D, Trischitta V, Vigneri R, Frittitta L
* The role of membrane glycoprotein plasma cell antigen 1 ectonucleotide pyrophosphatase phosphodiesterase 1 in the pathogenesis of insulin resistance and related abnormalities (629 views)
Endocrine Reviews (ISSN: 0163-769x), 2008 Feb; 29(1): 62-75.
Impact Factor: 18.562
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Marchelli R, Saviano M, Licandro E, Spoto G, Borgatti M, Gambari R
* PNAs targeting the "RNA world": Micro RNA next? (384 views)
Minerva Biotecnol (ISSN: 1120-4826), 2008; 20(4): 183-188.
Impact Factor: 0.1
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Malaguarnera R, Vella V, Pandini G, Sanfilippo M, Pezzino V, Vigneri R, Frasca F
* TAp73α increases p53 tumor suppressor activity in thyroid cancer cells via the inhibition of Mdm2-mediated degradation (411 views)
Mol Cancer Res (ISSN: 1541-7786), 2008; 6(1): 64-77.
Impact Factor: 4.533
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Sorriento D, Ciccarelli M, Santulli G, Campanile A, Altobelli GG, Cimini V, Galasso G, Astone D, Piscione F, Pastore L, Trimarco B, Iaccarino G
* The G-protein-coupled receptor kinase 5 inhibits NFκB transcriptional activity by inducing nuclear accumulation of IκBα (419 views)
P Natl Acad Sci Usa (ISSN: 0027-8424, 1091-6490, 0027-8424print), 2008; 105(46): 17818-17823.
Impact Factor: 9.38
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Ruggiero A, Tizzano B, Geerlof A, Pedone E, Pedone C, Wilmanns M, Berisio R
* Expression, purification, crystallization and preliminary X-ray crystallographic analysis of a resuscitation-promoting factor from Mycobacterium tuberculosis (363 views)
Nucleosides Nucleotides Nucleic Acids (ISSN: 1744-3091, 1744-4309), 2007 Oct 1; 63(10): 870-873.
Impact Factor: 0.645
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Pensato S, Saviano M, Romanelli A
* New peptide nucleic acid analogues: synthesis and applications (457 views)
Expert Opinion On Biological Therapy (ISSN: 1471-2598), 2007 Sep; 7(8): 1219-1232.
Impact Factor: 2.815
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Limauro D, Pedone E, Pirone L, Bartolucci S
* Identification and characterization of 1-Cys peroxiredoxin from Sulfolobus solfataricus and its involvement in the response to oxidative stress (332 views)
Febs Journal (ISSN: 1742-464x), 2006 Feb; 273(4): 721-731.
Impact Factor: 3.033
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Copani A, Hoozemans JJM, Caraci F, Calafiore M, Van Haastert ES, Veerhuis R, Rozemuller AJM, Aronica E, Sortino MA, Nicoletti F
* Dna Polymerase-Beta Is Expressed Early In Neurons Of Alzheimer'S Disease Brain And Is Loaded Into Dna Replication Forks In Neurons Challenged With Beta-Amyloid (461 views)
J Neurosci (ISSN: 0270-6474, 0361-803x, 1529-2401), 2006; 26(43): 10949-10957.
Impact Factor: 2.117
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Fiory F, Alberobello AT, Miele C, Oriente F, Esposito I, Corbo V, Ruvo M, Tizzano B, Rasmussen TE, Gammeltoft S, Formisano P, Beguinot F
* Tyrosine phosphorylation of phosphoinositide-dependent kinase 1 by the insulin receptor is necessary for insulin metabolic signaling (450 views)
Mol Cell Biol (ISSN: 0270-7306, 1098-5549), 2005 Dec; 25(24): 10803-10814.
Impact Factor: 7.093
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Foti D, Chiefari E, Fedele M, Iuliano R, Brunetti L, Paonessa F, Manfioletti G, Barbetti F, Brunetti A, Croce CM, Fusco A, Brunetti A
* Lack of the architectural factor HMGA1 causes insulin resistance and diabetes in humans and mice (375 views)
Nat Med (ISSN: 1078-8956, 0034-7264), 2005 Jul; 11(7): 765-773.
Impact Factor: 28.878
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Saviano M, Isernia C, Bassarello C, Di Lello P, Galdiero S, Mierke DF, Benedetti E, Pedone C
* Conformational analysis by NMR and distance geometry techniques of a peptide mimetic of the third helix of the Antennapedia homeodomain (429 views)
J Pept Res (ISSN: 1397-002x), 2005 Feb; 65(2): 200-208.
Impact Factor: 1.741
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Borgatti M, Boyd DD, Lampronti I, Bianchi N, Fabbri E, Saviano M, Romanelli A, Pedone C, Gambari R
* Decoy molecules based on PNA-DNA chimeras and targeting Sp1 transcription factors inhibit the activity of urokinase-type plasminogen activator receptor (uPAR) promoter (384 views)
Oncology Research (ISSN: 0965-0407), 2005; 15(7-8): 373-383.
Impact Factor: 1.844
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Rivieccio V, Mannini R, Concilio L, D'Auria S, Pedone C, Grimaldi G
* Expression, purification and partial characterization of the Krüppel-associated box (KRAB) from the human ZNF2 protein (278 views)
Protein Pept Lett (ISSN: 0929-8665, 1875-5305), 2005; 12(6): 527-532.
Impact Factor: 0.84
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Borgatti M, Finotti A, Romanelli A, Saviano M, Bianchi N, Lampronti I, Lambertini E, Penolazzi L, Nastruzzi C, Mischiati C, Piva R, Pedone C, Gambari R
* Peptide nucleic acids (PNA)-DNA chimeras targeting transcription factors as a tool to modify gene expression (470 views)
Curr Drug Targets (ISSN: 1389-4501), 2004 Nov; 5(8): 735-744.
Impact Factor: 4.104
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Penolazzi L, Borgatti M, Lambertini E, Mischiati C, Finotti A, Romanelli A, Saviano M, Pedone C, Piva R, Gambari R
* Peptide nucleic acid-DNA decoy chimeras targeting NF-kappa B transcription factors: Induction of apoptosis in human primary osteoclasts (306 views)
International Journal Of Molecular Medicine (ISSN: 1107-3756), 2004 Sep; 14(2): 145-152.
Impact Factor: 3.19
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Caricasole A, Copani A, Caraci F, Aronica E, Rozemuller AJ, Caruso A, Storto M, Gaviraghi G, Terstappen GC, Nicoletti F
* Induction of Dickkopf-1, a negative modulator of the Wnt pathway, is associated with neuronal degeneration in Alzheimer's brain (498 views)
J Neurosci (ISSN: 0270-6474, 0361-803x, 1529-2401), 2004 Jun 30; 24(26): 6021-6027.
Impact Factor: 2.384
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Isernia C, Bucci E, Leone M, Zaccaro L, Di Lello P, Digilio G, Esposito S, Saviano M, Di Blasio B, Pedone C, Pedone PV, Fattorusso R
* NMR structure of the single QALGGH zinc finger domain from the Arabidopsis thaliana SUPERMAN protein (412 views)
Chembiochem (ISSN: 1439-4227, 1439-7633, 1439-7633electronic), 2003 Mar 3; 4(2-3): 171-180.
Impact Factor: 3.992
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Esposito G, Ligresti A, Izzo AA, Bisogno T, Ruvo M, Di Rosa M, Di Marzo V, Iuvone T
* The endocannabinoid system protects rat glioma cells against HIV-1 Tat protein-induced cytotoxicity: Mechanism and regulation (459 views)
Jbc Papers (ISSN: 0021-9258, 1083-351x, 0021-9258linking), 2002 Dec 27; 277(52): 50348-50354.
Impact Factor: 6.696
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Dathan N, Zaccaro L, Esposito S, Isernia C, Omichinski JG, Riccio A, Pedone C, Di Blasio B, Fattorusso R, Pedone PV
* The Arabidopsis SUPERMAN protein is able to specifically bind DNA through its single Cys(2)-His(2) zinc finger motif (550 views)
Nucleic Acids Res (ISSN: 0305-1048, 1362-4962, 1362-4962electronic), 2002 Nov 15; 30(22): 4945-4951.
Impact Factor: 7.051
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Borgatti M, Breda L, Cortesi R, Nastruzzi C, Romanelli A, Saviano M, Bianchi N, Mischiati C, Pedone C, Gambari R
* Cationic Liposomes As Delivery Systems For Double-Stranded Pna-Dna Chimeras Exhibiting Decoy Activity Against Nf-Kappab Transcription Factors (395 views)
Biochem Pharmacol Biochemical Pharmacology (ISSN: 1873-2968, 0006-2952), 2002 Sep 15; 64(4): 609-616.
Impact Factor: 3.542
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Zell R, Sidigi K, Bucci E, Stelzner A, Goerlach M
* Determinants of the recognition of enteroviral cloverleaf RNA by coxsackievirus B3 proteinase 3C (389 views)
Rna (ISSN: 1355-8382), 2002; 8(2): 188-201.
Impact Factor: 5.099
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Romanelli A, Pedone C, Saviano M, Bianchi N, Borgatti M, Mischiati C, Gambari R
* Molecular interactions between nuclear factor κB (NF-κB) transcription factors and a PNA-DNA chimera mimicking NF-κB binding sites (403 views)
Eur J Biochem (ISSN: 0014-2956, 0014-2956print, 0014-2956linking), 2001 Dec; 268(23): 6066-6075.
Impact Factor: 2.849
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Romanelli A, Pedone C, Saviano M, Bianchi N, Borgatti M, Mischiati C, Gambari R
* Molecular interactions with nuclear factor kappaB (NF-kappaB) transcription factors of a PNA-DNA chimera mimicking NF-kappaB binding sites (409 views)
Eur J Biochem (ISSN: 0014-2956print, 0014-2956linking), 2001 Dec; 268(23): 6066-6075.
Impact Factor: 4.779
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Del Vecchio S, Ciarmiello A, Salvatore M
Clinical imaging of multidrug resistance in cancer (352 views)
Q J Nucl Med (ISSN: 1124-3937, 1125-0135), 1999 Jun; 43(2): 125-131.
Impact Factor: 2.125
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Levchenko A, Mehta B, Spengler BA, Narkar A, Fonti R, Biedler JL, Tsuruo T, Larson SM
Measurement of P-glycoprotein expression in multidrug-resistant human neuroblastoma cell lines using self-competitive binding assay (252 views)
Anal Biochem (ISSN: 0003-2697, 1096-0309electronic, 0003-2697linking), 1996 May 1; 236(2): 338-343.
Impact Factor: 2.017
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Marotta T, Ferrara LA, Di Marino L, Mancini M, Annuzzi G, Russo O, D'Orta G, Lucarelli C, Rossi F
Factors affecting lipoprotein lipase in hypertensive patients (316 views)
Metab Clin Exp (ISSN: 0026-0495, 1532-8600), 1995 Jun; 44(6): 712-718.
Impact Factor: 1.681
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Oliva A, Della Ragione F, Fratta M, Marrone G, Palumbo R, Zappia V
Effect of retinoic acid on osteocalcin gene expression in human osteoblasts (252 views)
Biochem Biophys Res Commun (ISSN: 0006-291xprint, 0006-291xlinking), 1993 Mar 31; 191(3): 908-914.
Impact Factor: 2.671
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Maglione D, Guerriero V, Viglietto G, Ferraro MG, Aprelikova O, Alitalo K, Del Vecchio S, Lei KJ, Chou JY, Persico MG
Two alternative mRNAs coding for the angiogenic factor, placenta growth factor (PlGF), are transcribed from a single gene of chromosome 14 (417 views)
Oncogene (ISSN: 0950-9232, 1476-5594), 1993; 8(4): 925-931.
Impact Factor: 6.772
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Scala S, Pacelli R, Iaffaioli RV, Normanno N, Pepe S, Frasci G, Genua G, Tsuruo T, Tagliaferri P, Bianco AR
Reversal of adriamycin resistance by recombinant α-interferon in multidrug-resistant human colon carcinoma LoVo-doxorubicin cells (553 views)
Cancer Res (ISSN: 0008-5472, 1538-7445, 1538-7445electronic), 1991 Sep 15; 51(18): 4898-4902.
Impact Factor: 8.426
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138 Records (127 excluding Abstracts).
Total impact factor: 697.034 (645.23 excluding Abstracts).
Total 5 year impact factor: 683.369 (630.41 excluding Abstracts).
Total impact factor: 697.034 (645.23 excluding Abstracts).
Total 5 year impact factor: 683.369 (630.41 excluding Abstracts).
362 views. Last view on Friday 07 October 2022, 20:07:14
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