A Simple Noninvasive Score Based on Routine Parameters can Predict Liver Cirrhosis in Patients With Chronic Hepatitis (333 views)
Hepat Mon (ISSN: 1735-143xprint, 1735-143xlinking), 2013 May 8; 13(5): e8352-e8352.
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Paper type: Journal Article,
Impact factor: 1.796, 5-year impact factor: 1.601
Url: https://www.scopus.com/inward/record.uri?eid=2-s2.0-84877647206&doi=10.5812%2fhepatmon.8352&partnerID=40&md5=9ed5541c483dc77a668c875d9a7cbbfb
Keywords: Adult, Alanine Transaminase, Blood, Analysis Of Variance, Area Under Curve, Aspartate Aminotransferases, Biological Markers, Female, Hepatitis C, Chronic, Humans, Liver Cirrhosis, Diagnosis, Pathology, Logistic Models, Middle Aged, Platelet Count, Roc Curve, Severity Of Illness Index, Young Adult, Alpha-Fetoproteins, Metabolism, Biopsy, Fibrosis, Noninvasive Ventilation, Prothrombin, Alcohol Consumption, Article, Human Tissue, Liver Biopsy, Major Clinical Study, Predictive Value, Receiver Operating Characteristic, Scoring System, Sensitivity And Specificity, Splenomegaly, Thrombocyte Count,
Affiliations:
*** IBB - CNR ***
Department of Clinical Medicine and Surgery, University of Naples Federico II, via S. Pansini, Naples, Italy.,
Department of Public Medicine, Section of Infectious Disease, Second University of Naples, Via L. Armanni, Naples, Italy
Institute of Biostructure and Bioimaging, National Research Council (CNR), Naples, Italy
Department of Advanced Biomedical Science, University of Naples Federico II, Via S. Pansini, Naples, Italy
References:
Lavanchy, D., The global burden of hepatitis C (2009) Liver Int, 29 (SUPPL. 1), pp. 74-8
Global burden of disease (GBD) for hepatitis C (2004) J Clin Pharmacol, 44 (1), pp. 20-29
Coppola, N., Pisapia, R., Tonziello, G., Masiello, A., Martini, S., Pisaturo, M., Improvement in the aetiological diagnosis of acute hepatitis C: A diagnostic protocol based on the anti-HCV-IgM titre and IgG Avidity Index (2009) J Clin Virol, 46 (3), pp. 222-229
Hoofnagle, J.H., Hepatitis C: The clinical spectrum of disease (1997) Hepatology, 26 (3 SUPPL. 1), pp. 15S-20S
Garcia-Tsao, G., Sanyal, A.J., Grace, N.D., Carey, W., Prevention and management of gastroesophageal varices and variceal hemorrhage in cirrhosis (2007) Hepatology, 46 (3), pp. 922-938
Lok, A.S., Ghany, M.G., Goodman, Z.D., Wright, E.C., Everson, G.T., Sterling, R.K., Predicting cirrhosis in patients with hepatitis C based on standard laboratory tests: Results of the HALT-C cohort (2005) Hepatology, 42 (2), pp. 282-292
Bedossa, P., Dargere, D., Paradis, V., Sampling variability of liver fibrosis in chronic hepatitis C (2003) Hepatology, 38 (6), pp. 1449-1457
Pagliaro, L., Rinaldi, F., Craxi, A., Di Piazza, S., Filippazzo, G., Gatto, G., Percutaneous blind biopsy versus laparoscopy with guided biopsy in diagnosis of cirrhosis. A prospective, randomized trial (1983) Dig Dis Sci, 28 (1), pp. 39-43
Regev, A., Berho, M., Jeffers, L.J., Milikowski, C., Molina, E.G., Pyrsopoulos, N.T., Sampling error and intraobserver variation in liver biopsy in patients with chronic HCV infection (2002) Am J Gastroenterol, 97 (10), pp. 2614-2618
Siddique, I., El-Naga, H.A., Madda, J.P., Memon, A., Hasan, F., Sampling variability on percutaneous liver biopsy in patients with chronic hepatitis C virus infection (2003) Scand J Gastroenterol, 38 (4), pp. 427-432
Cadranel, J.F., Rufat, P., Degos, F., Practices of liver biopsy in France: Results of a prospective nationwide survey. For the Group of Epidemiology of the French Association for the Study of the Liver (AFEF) (2000) Hepatology, 32 (3), pp. 477-481
Janes, C.H., Lindor, K.D., Outcome of patients hospitalized for complications after outpatient liver biopsy (1993) Ann Intern Med, 118 (2), pp. 96-98
Perrault, J., McGill, D.B., Ott, B.J., Taylor, W.F., Liver biopsy: Complications in 1000 inpatients and outpatients (1978) Gastroenterology, 74 (1), pp. 103-106
Sagnelli, E., Sagnelli, C., Pisaturo, M.A., Coppola, N., Pasquale, G., Piccinino, F., Liver biopsy in chronic hepatitis C: The experience of 15 Italian wards of infectious diseases (2012) Infez Med, 20 (1), pp. 31-36
Poynard, T., Morra, R., Ingiliz, P., Imbert-Bismut, F., Thabut, D., Messous, D., Assessment of liver fibrosis: Noninvasive means (2008) Saudi J Gastroenterol, 14 (4), pp. 163-173
Rockey, D.C., Bissell, D.M., Noninvasive measures of liver fibrosis (2006) Hepatology, 43 (2 SUPPL. 1), pp. S113-S120
Ziol, M., Handra-Luca, A., Kettaneh, A., Christidis, C., Mal, F., Kazemi, F., Noninvasive assessment of liver fibrosis by measurement of stiffness in patients with chronic hepatitis C (2005) Hepatology, 41 (1), pp. 48-54
Imbert-Bismut, F., Ratziu, V., Pieroni, L., Charlotte, F., Benhamou, Y., Poynard, T., Biochemical markers of liver fibrosis in patients with hepatitis C virus infection: A prospective study (2001) Lancet, 357 (9262), pp. 1069-1075
Patel, K., Friedrich-Rust, M., Lurie, Y., Grigorescu, M., Stanciu, C., Lee, C.M., FibroSURE and FibroScan in relation to treatment response in chronic hepatitis C virus (2011) World J Gastroenterol, 17 (41), pp. 4581-4589
Berres, M.L., Schlosser, B., Berg, T., Trautwein, C., Wasmuth, H.E., Soluble urokinase plasminogen activator receptor is associated with progressive liver fibrosis in hepatitis C infection (2012) J Clin Gastroenterol, 46 (4), pp. 334-338
Fortunato, G., Castaldo, G., Oriani, G., Cerini, R., Intrieri, M., Molinaro, E., Multivariate discriminant function based on six biochemical markers in blood can predict the cirrhotic evolution of chronic hepatitis (2001) Clin Chem, 47 (9), pp. 1696-1700
Ho, A.S., Cheng, C.C., Lee, S.C., Liu, M.L., Lee, J.Y., Wang, W.M., Novel biomarkers predict liver fibrosis in hepatitis C patients: Alpha 2 macroglobulin, vitamin D binding protein and apolipoprotein AI (2010) J Biomed Sci, 17, p. 58
Kovalenko, E., Tacke, F., Gressner, O.A., Zimmermann, H.W., Lahme, B., Janetzko, A., Validation of connective tissue growth factor (CTGF/CCN2) and its gene polymorphisms as noninvasive biomarkers for the assessment of liver fibrosis (2009) J Viral Hepat, 16 (9), pp. 612-620
Mehta, P., Ploutz-Snyder, R., Nandi, J., Rawlins, S.R., Sanderson, S.O., Levine, R.A., Diagnostic accuracy of serum hyaluronic acid, FIBROSpect II, and YKL-40 for discriminating fibrosis stages in chronic hepatitis C (2008) Am J Gastroenterol, 103 (4), pp. 928-936
Saitou, Y., Shiraki, K., Yamanaka, Y., Yamaguchi, Y., Kawakita, T., Yamamoto, N., Noninvasive estimation of liver fibrosis and response to interferon therapy by a serum fibrogenesis marker, YKL-40, in patients with HCV-associated liver disease (2005) World J Gastroenterol, 11 (4), pp. 476-481
Selim, H.S., El-Barrawy, M.A., Taha, H.A., Abd El-Hafiz, D.A., Evaluation of Interleukin-18 as a Non Invasive Marker of Liver Fibrosis among Chronic Hepatitis C Virus Patients (2009) J Egypt Public Health Assoc, 84 (5-6), pp. 391-403
Valva, P., Casciato, P., Diaz Carrasco, J.M., Gadano, A., Galdame, O., Galoppo, M.C., The role of serum biomarkers in predicting fibrosis progression in pediatric and adult hepatitis C virus chronic infection (2011) PLoS One, 6 (8), pp. e23218
Bonacini, M., Hadi, G., Govindarajan, S., Lindsay, K.L., Utility of a discriminant score for diagnosing advanced fibrosis or cirrhosis in patients with chronic hepatitis C virus infection (1997) Am J Gastroenterol, 92 (8), pp. 1302-1304
Cross, T.J., Rizzi, P., Berry, P.A., Bruce, M., Portmann, B., Harrison, P.M., King's Score: An accurate marker of cirrhosis in chronic hepatitis C (2009) Eur J Gastroenterol Hepatol, 21 (7), pp. 730-738
Forns, X., Ampurdanes, S., Llovet, J.M., Aponte, J., Quinto, L., Martinez-Bauer, E., Identification of chronic hepatitis C patients without hepatic fibrosis by a simple predictive model (2002) Hepatology, 36 (4 Pt 1), pp. 986-992
Giannini, E., Risso, D., Botta, F., Chiarbonello, B., Fasoli, A., Malfatti, F., Validity and clinical utility of the aspartate aminotransferase-alanine aminotransferase ratio in assessing disease severity and prognosis in patients with hepatitis C virus-related chronic liver disease (2003) Arch Intern Med, 163 (2), pp. 218-224
Imperiale, T.F., Said, A.T., Cummings, O.W., Born, L.J., Need for validation of clinical decision aids: Use of the AST/ALT ratio in predicting cirrhosis in chronic hepatitis C (2000) Am J Gastroenterol, 95 (9), pp. 2328-2332
Islam, S., Antonsson, L., Westin, J., Lagging, M., Cirrhosis in hepatitis C virus-infected patients can be excluded using an index of standard biochemical serum markers (2005) Scand J Gastroenterol, 40 (7), pp. 867-872
Kim, B.K., do, Y.K., Park, J.Y., Ahn, S.H., Chon, C.Y., Kim, J.K., Validation of FIB-4 and comparison with other simple noninvasive indices for predicting liver fibrosis and cirrhosis in hepatitis B virus-infected patients (2010) Liver Int, 30 (4), pp. 546-553
Lackner, C., Struber, G., Liegl, B., Leibl, S., Ofner, P., Bankuti, C., Comparison and validation of simple noninvasive tests for prediction of fibrosis in chronic hepatitis C (2005) Hepatology, 41 (6), pp. 1376-1382
Luo, J.C., Hwang, S.J., Chang, F.Y., Chu, C.W., Lai, C.R., Wang, Y.J., Simple blood tests can predict compensated liver cirrhosis in patients with chronic hepatitis C (2002) Hepatogastroenterology, 49 (44), pp. 478-481
Park, G.J., Lin, B.P., Ngu, M.C., Jones, D.B., Katelaris, P.H., Aspartate aminotransferase: Alanine aminotransferase ratio in chronic hepatitis C infection: Is it a useful predictor of cirrhosis? (2000) J Gastroenterol Hepatol, 15 (4), pp. 386-390
Pohl, A., Behling, C., Oliver, D., Kilani, M., Monson, P., Hassanein, T., Serum aminotransferase levels and platelet counts as predictors of degree of fibrosis in chronic hepatitis C virus infection (2001) Am J Gastroenterol, 96 (11), pp. 3142-3146
Sheth, S.G., Flamm, S.L., Gordon, F.D., Chopra, S., AST/ALT ratio predicts cirrhosis in patients with chronic hepatitis C virus infection (1998) Am J Gastroenterol, 93 (1), pp. 44-48
Wai, C.T., Greenson, J.K., Fontana, R.J., Kalbfleisch, J.D., Marrero, J.A., Conjeevaram, H.S., A simple noninvasive index can predict both significant fibrosis and cirrhosis in patients with chronic hepatitis C (2003) Hepatology, 38 (2), pp. 518-526
Kaul, V., Friedenberg, F.K., Braitman, L.E., Anis, U., Zaeri, N., Fazili, J., Development and validation of a model to diagnose cirrhosis in patients with hepatitis C (2002) Am J Gastroenterol, 97 (10), pp. 2623-2628
Ishak, K., Baptista, A., Bianchi, L., Callea, F., de Groote, J., Gudat, F., Histological grading and staging of chronic hepatitis (1995) J Hepatol, 22 (6), pp. 696-699
Frank, K., Linhart, P., Kortsik, C., Wohlenberg H. [Sonographic determination of spleen size: Normal dimensions in adults with a healthy spleen] (1986) Ultraschall Med, 7 (3), pp. 134-137
Hanley, J.A., McNeil, B.J., The meaning and use of the area under a receiver operating characteristic (ROC) curve (1982) Radiology, 143 (1), pp. 29-36
Delong, E.R., Delong, D.M., Clarke-Pearson, D.L., Comparing the areas under two or more correlated receiver operating characteristic curves: A nonparametric approach (1988) Biometrics, 44 (3), pp. 837-845
Gentile, I., Viola, C., Graf, M., Liuzzi, R., Quarto, M., Cerini, R., A simple noninvasive score predicts gastroesophageal varices in patients with chronic viral hepatitis (2009) J Clin Gastroenterol, 43 (1), pp. 81-87
Pradat, P., Voirin, N., Tillmann, H.L., Chevallier, M., Trepo, C., Progression to cirrhosis in hepatitis C patients: An age-dependent process (2007) Liver Int, 27 (3), pp. 335-339
Peck-Radosavljevic, M., Zacherl, J., Meng, Y.G., Pidlich, J., Lipinski, E., Langle, F., Is inadequate thrombopoietin production a major cause of thrombocytopenia in cirrhosis of the liver? (1997) J Hepatol, 27 (1), pp. 127-131
Gentile, I., Thabut, D., Noninvasive prediction of oesophageal varices: As simple as blood count? (2010) Liver Int, 30 (8), pp. 1091-1093
Hepat Mon (ISSN: 1735-143xprint, 1735-143xlinking), 2013 May 8; 13(5): e8352-e8352.
Export to BibTeX Export to EndNote
Paper type: Journal Article,
Impact factor: 1.796, 5-year impact factor: 1.601
Url: https://www.scopus.com/inward/record.uri?eid=2-s2.0-84877647206&doi=10.5812%2fhepatmon.8352&partnerID=40&md5=9ed5541c483dc77a668c875d9a7cbbfb
Keywords: Adult, Alanine Transaminase, Blood, Analysis Of Variance, Area Under Curve, Aspartate Aminotransferases, Biological Markers, Female, Hepatitis C, Chronic, Humans, Liver Cirrhosis, Diagnosis, Pathology, Logistic Models, Middle Aged, Platelet Count, Roc Curve, Severity Of Illness Index, Young Adult, Alpha-Fetoproteins, Metabolism, Biopsy, Fibrosis, Noninvasive Ventilation, Prothrombin, Alcohol Consumption, Article, Human Tissue, Liver Biopsy, Major Clinical Study, Predictive Value, Receiver Operating Characteristic, Scoring System, Sensitivity And Specificity, Splenomegaly, Thrombocyte Count,
Affiliations:
*** IBB - CNR ***
Department of Clinical Medicine and Surgery, University of Naples Federico II, via S. Pansini, Naples, Italy.,
Department of Public Medicine, Section of Infectious Disease, Second University of Naples, Via L. Armanni, Naples, Italy
Institute of Biostructure and Bioimaging, National Research Council (CNR), Naples, Italy
Department of Advanced Biomedical Science, University of Naples Federico II, Via S. Pansini, Naples, Italy
References:
Lavanchy, D., The global burden of hepatitis C (2009) Liver Int, 29 (SUPPL. 1), pp. 74-8
Global burden of disease (GBD) for hepatitis C (2004) J Clin Pharmacol, 44 (1), pp. 20-29
Coppola, N., Pisapia, R., Tonziello, G., Masiello, A., Martini, S., Pisaturo, M., Improvement in the aetiological diagnosis of acute hepatitis C: A diagnostic protocol based on the anti-HCV-IgM titre and IgG Avidity Index (2009) J Clin Virol, 46 (3), pp. 222-229
Hoofnagle, J.H., Hepatitis C: The clinical spectrum of disease (1997) Hepatology, 26 (3 SUPPL. 1), pp. 15S-20S
Garcia-Tsao, G., Sanyal, A.J., Grace, N.D., Carey, W., Prevention and management of gastroesophageal varices and variceal hemorrhage in cirrhosis (2007) Hepatology, 46 (3), pp. 922-938
Lok, A.S., Ghany, M.G., Goodman, Z.D., Wright, E.C., Everson, G.T., Sterling, R.K., Predicting cirrhosis in patients with hepatitis C based on standard laboratory tests: Results of the HALT-C cohort (2005) Hepatology, 42 (2), pp. 282-292
Bedossa, P., Dargere, D., Paradis, V., Sampling variability of liver fibrosis in chronic hepatitis C (2003) Hepatology, 38 (6), pp. 1449-1457
Pagliaro, L., Rinaldi, F., Craxi, A., Di Piazza, S., Filippazzo, G., Gatto, G., Percutaneous blind biopsy versus laparoscopy with guided biopsy in diagnosis of cirrhosis. A prospective, randomized trial (1983) Dig Dis Sci, 28 (1), pp. 39-43
Regev, A., Berho, M., Jeffers, L.J., Milikowski, C., Molina, E.G., Pyrsopoulos, N.T., Sampling error and intraobserver variation in liver biopsy in patients with chronic HCV infection (2002) Am J Gastroenterol, 97 (10), pp. 2614-2618
Siddique, I., El-Naga, H.A., Madda, J.P., Memon, A., Hasan, F., Sampling variability on percutaneous liver biopsy in patients with chronic hepatitis C virus infection (2003) Scand J Gastroenterol, 38 (4), pp. 427-432
Cadranel, J.F., Rufat, P., Degos, F., Practices of liver biopsy in France: Results of a prospective nationwide survey. For the Group of Epidemiology of the French Association for the Study of the Liver (AFEF) (2000) Hepatology, 32 (3), pp. 477-481
Janes, C.H., Lindor, K.D., Outcome of patients hospitalized for complications after outpatient liver biopsy (1993) Ann Intern Med, 118 (2), pp. 96-98
Perrault, J., McGill, D.B., Ott, B.J., Taylor, W.F., Liver biopsy: Complications in 1000 inpatients and outpatients (1978) Gastroenterology, 74 (1), pp. 103-106
Sagnelli, E., Sagnelli, C., Pisaturo, M.A., Coppola, N., Pasquale, G., Piccinino, F., Liver biopsy in chronic hepatitis C: The experience of 15 Italian wards of infectious diseases (2012) Infez Med, 20 (1), pp. 31-36
Poynard, T., Morra, R., Ingiliz, P., Imbert-Bismut, F., Thabut, D., Messous, D., Assessment of liver fibrosis: Noninvasive means (2008) Saudi J Gastroenterol, 14 (4), pp. 163-173
Rockey, D.C., Bissell, D.M., Noninvasive measures of liver fibrosis (2006) Hepatology, 43 (2 SUPPL. 1), pp. S113-S120
Ziol, M., Handra-Luca, A., Kettaneh, A., Christidis, C., Mal, F., Kazemi, F., Noninvasive assessment of liver fibrosis by measurement of stiffness in patients with chronic hepatitis C (2005) Hepatology, 41 (1), pp. 48-54
Imbert-Bismut, F., Ratziu, V., Pieroni, L., Charlotte, F., Benhamou, Y., Poynard, T., Biochemical markers of liver fibrosis in patients with hepatitis C virus infection: A prospective study (2001) Lancet, 357 (9262), pp. 1069-1075
Patel, K., Friedrich-Rust, M., Lurie, Y., Grigorescu, M., Stanciu, C., Lee, C.M., FibroSURE and FibroScan in relation to treatment response in chronic hepatitis C virus (2011) World J Gastroenterol, 17 (41), pp. 4581-4589
Berres, M.L., Schlosser, B., Berg, T., Trautwein, C., Wasmuth, H.E., Soluble urokinase plasminogen activator receptor is associated with progressive liver fibrosis in hepatitis C infection (2012) J Clin Gastroenterol, 46 (4), pp. 334-338
Fortunato, G., Castaldo, G., Oriani, G., Cerini, R., Intrieri, M., Molinaro, E., Multivariate discriminant function based on six biochemical markers in blood can predict the cirrhotic evolution of chronic hepatitis (2001) Clin Chem, 47 (9), pp. 1696-1700
Ho, A.S., Cheng, C.C., Lee, S.C., Liu, M.L., Lee, J.Y., Wang, W.M., Novel biomarkers predict liver fibrosis in hepatitis C patients: Alpha 2 macroglobulin, vitamin D binding protein and apolipoprotein AI (2010) J Biomed Sci, 17, p. 58
Kovalenko, E., Tacke, F., Gressner, O.A., Zimmermann, H.W., Lahme, B., Janetzko, A., Validation of connective tissue growth factor (CTGF/CCN2) and its gene polymorphisms as noninvasive biomarkers for the assessment of liver fibrosis (2009) J Viral Hepat, 16 (9), pp. 612-620
Mehta, P., Ploutz-Snyder, R., Nandi, J., Rawlins, S.R., Sanderson, S.O., Levine, R.A., Diagnostic accuracy of serum hyaluronic acid, FIBROSpect II, and YKL-40 for discriminating fibrosis stages in chronic hepatitis C (2008) Am J Gastroenterol, 103 (4), pp. 928-936
Saitou, Y., Shiraki, K., Yamanaka, Y., Yamaguchi, Y., Kawakita, T., Yamamoto, N., Noninvasive estimation of liver fibrosis and response to interferon therapy by a serum fibrogenesis marker, YKL-40, in patients with HCV-associated liver disease (2005) World J Gastroenterol, 11 (4), pp. 476-481
Selim, H.S., El-Barrawy, M.A., Taha, H.A., Abd El-Hafiz, D.A., Evaluation of Interleukin-18 as a Non Invasive Marker of Liver Fibrosis among Chronic Hepatitis C Virus Patients (2009) J Egypt Public Health Assoc, 84 (5-6), pp. 391-403
Valva, P., Casciato, P., Diaz Carrasco, J.M., Gadano, A., Galdame, O., Galoppo, M.C., The role of serum biomarkers in predicting fibrosis progression in pediatric and adult hepatitis C virus chronic infection (2011) PLoS One, 6 (8), pp. e23218
Bonacini, M., Hadi, G., Govindarajan, S., Lindsay, K.L., Utility of a discriminant score for diagnosing advanced fibrosis or cirrhosis in patients with chronic hepatitis C virus infection (1997) Am J Gastroenterol, 92 (8), pp. 1302-1304
Cross, T.J., Rizzi, P., Berry, P.A., Bruce, M., Portmann, B., Harrison, P.M., King's Score: An accurate marker of cirrhosis in chronic hepatitis C (2009) Eur J Gastroenterol Hepatol, 21 (7), pp. 730-738
Forns, X., Ampurdanes, S., Llovet, J.M., Aponte, J., Quinto, L., Martinez-Bauer, E., Identification of chronic hepatitis C patients without hepatic fibrosis by a simple predictive model (2002) Hepatology, 36 (4 Pt 1), pp. 986-992
Giannini, E., Risso, D., Botta, F., Chiarbonello, B., Fasoli, A., Malfatti, F., Validity and clinical utility of the aspartate aminotransferase-alanine aminotransferase ratio in assessing disease severity and prognosis in patients with hepatitis C virus-related chronic liver disease (2003) Arch Intern Med, 163 (2), pp. 218-224
Imperiale, T.F., Said, A.T., Cummings, O.W., Born, L.J., Need for validation of clinical decision aids: Use of the AST/ALT ratio in predicting cirrhosis in chronic hepatitis C (2000) Am J Gastroenterol, 95 (9), pp. 2328-2332
Islam, S., Antonsson, L., Westin, J., Lagging, M., Cirrhosis in hepatitis C virus-infected patients can be excluded using an index of standard biochemical serum markers (2005) Scand J Gastroenterol, 40 (7), pp. 867-872
Kim, B.K., do, Y.K., Park, J.Y., Ahn, S.H., Chon, C.Y., Kim, J.K., Validation of FIB-4 and comparison with other simple noninvasive indices for predicting liver fibrosis and cirrhosis in hepatitis B virus-infected patients (2010) Liver Int, 30 (4), pp. 546-553
Lackner, C., Struber, G., Liegl, B., Leibl, S., Ofner, P., Bankuti, C., Comparison and validation of simple noninvasive tests for prediction of fibrosis in chronic hepatitis C (2005) Hepatology, 41 (6), pp. 1376-1382
Luo, J.C., Hwang, S.J., Chang, F.Y., Chu, C.W., Lai, C.R., Wang, Y.J., Simple blood tests can predict compensated liver cirrhosis in patients with chronic hepatitis C (2002) Hepatogastroenterology, 49 (44), pp. 478-481
Park, G.J., Lin, B.P., Ngu, M.C., Jones, D.B., Katelaris, P.H., Aspartate aminotransferase: Alanine aminotransferase ratio in chronic hepatitis C infection: Is it a useful predictor of cirrhosis? (2000) J Gastroenterol Hepatol, 15 (4), pp. 386-390
Pohl, A., Behling, C., Oliver, D., Kilani, M., Monson, P., Hassanein, T., Serum aminotransferase levels and platelet counts as predictors of degree of fibrosis in chronic hepatitis C virus infection (2001) Am J Gastroenterol, 96 (11), pp. 3142-3146
Sheth, S.G., Flamm, S.L., Gordon, F.D., Chopra, S., AST/ALT ratio predicts cirrhosis in patients with chronic hepatitis C virus infection (1998) Am J Gastroenterol, 93 (1), pp. 44-48
Wai, C.T., Greenson, J.K., Fontana, R.J., Kalbfleisch, J.D., Marrero, J.A., Conjeevaram, H.S., A simple noninvasive index can predict both significant fibrosis and cirrhosis in patients with chronic hepatitis C (2003) Hepatology, 38 (2), pp. 518-526
Kaul, V., Friedenberg, F.K., Braitman, L.E., Anis, U., Zaeri, N., Fazili, J., Development and validation of a model to diagnose cirrhosis in patients with hepatitis C (2002) Am J Gastroenterol, 97 (10), pp. 2623-2628
Ishak, K., Baptista, A., Bianchi, L., Callea, F., de Groote, J., Gudat, F., Histological grading and staging of chronic hepatitis (1995) J Hepatol, 22 (6), pp. 696-699
Frank, K., Linhart, P., Kortsik, C., Wohlenberg H. [Sonographic determination of spleen size: Normal dimensions in adults with a healthy spleen] (1986) Ultraschall Med, 7 (3), pp. 134-137
Hanley, J.A., McNeil, B.J., The meaning and use of the area under a receiver operating characteristic (ROC) curve (1982) Radiology, 143 (1), pp. 29-36
Delong, E.R., Delong, D.M., Clarke-Pearson, D.L., Comparing the areas under two or more correlated receiver operating characteristic curves: A nonparametric approach (1988) Biometrics, 44 (3), pp. 837-845
Gentile, I., Viola, C., Graf, M., Liuzzi, R., Quarto, M., Cerini, R., A simple noninvasive score predicts gastroesophageal varices in patients with chronic viral hepatitis (2009) J Clin Gastroenterol, 43 (1), pp. 81-87
Pradat, P., Voirin, N., Tillmann, H.L., Chevallier, M., Trepo, C., Progression to cirrhosis in hepatitis C patients: An age-dependent process (2007) Liver Int, 27 (3), pp. 335-339
Peck-Radosavljevic, M., Zacherl, J., Meng, Y.G., Pidlich, J., Lipinski, E., Langle, F., Is inadequate thrombopoietin production a major cause of thrombocytopenia in cirrhosis of the liver? (1997) J Hepatol, 27 (1), pp. 127-131
Gentile, I., Thabut, D., Noninvasive prediction of oesophageal varices: As simple as blood count? (2010) Liver Int, 30 (8), pp. 1091-1093
A Simple Noninvasive Score Based on Routine Parameters can Predict Liver Cirrhosis in Patients With Chronic Hepatitis
BACKGROUND: Liver biopsy has remained the gold standard for the diagnosis of chronic hepatitis C; even though, it has a low but non-negligible rate of both false negative and complications. Several authors have proposed noninvasive tools to diagnose cirrhosis. But none of them showed complete concordance with liver biopsy. OBJECTIVES: To devise a score based on noninvasive routine parameters that discriminate between patients with a high risk, and those with a low risk of cirrhosis among patients with chronic hepatitis C without performing liver biopsy, and to compare this score with other ones using routine parameters devoted to this aim. PATIENTS AND METHODS: We reviewed the charts of patients with chronic hepatitis C who performed a liver biopsy between 2000 and 2004. Multivariate analysis was used to identify independent predictors of cirrhosis. An independent group of patients with chronic hepatitis C admitted for a liver biopsy between 2007 and 2012 constituted the validation set. RESULTS: We enrolled 249 patients who had complete laboratoristic data, and sufficient liver tissue for fibrosis staging. Age, AST, prothrombin activity, and platelets were identified as independent predictors of histological cirrhosis. We categorized these variables, and devised a novel score called CISCUN (Cirrhosis Score University of Naples), giving one point to each of the following predictors: age > 40 years; AST > 2 upper normal values; platelet count < 160.000/mmc; prothrombin activity < 100%. Cirrhosis rate was 2.9% for the 103 patients with a CISCUN = 0 or 1, 23.4% for the 124 patients with a CISCUN of 2 or 3, and 86.4% for the 22 patients with a CISCUN = 4. These results were confirmed in the independent validation group of 285 patients with similar characteristics. CONCLUSIONS: Patients with chronic hepatitis C and with a CISCUN
BACKGROUND: Liver biopsy has remained the gold standard for the diagnosis of chronic hepatitis C; even though, it has a low but non-negligible rate of both false negative and complications. Several authors have proposed noninvasive tools to diagnose cirrhosis. But none of them showed complete concordance with liver biopsy. OBJECTIVES: To devise a score based on noninvasive routine parameters that discriminate between patients with a high risk, and those with a low risk of cirrhosis among patients with chronic hepatitis C without performing liver biopsy, and to compare this score with other ones using routine parameters devoted to this aim. PATIENTS AND METHODS: We reviewed the charts of patients with chronic hepatitis C who performed a liver biopsy between 2000 and 2004. Multivariate analysis was used to identify independent predictors of cirrhosis. An independent group of patients with chronic hepatitis C admitted for a liver biopsy between 2007 and 2012 constituted the validation set. RESULTS: We enrolled 249 patients who had complete laboratoristic data, and sufficient liver tissue for fibrosis staging. Age, AST, prothrombin activity, and platelets were identified as independent predictors of histological cirrhosis. We categorized these variables, and devised a novel score called CISCUN (Cirrhosis Score University of Naples), giving one point to each of the following predictors: age > 40 years; AST > 2 upper normal values; platelet count < 160.000/mmc; prothrombin activity < 100%. Cirrhosis rate was 2.9% for the 103 patients with a CISCUN = 0 or 1, 23.4% for the 124 patients with a CISCUN of 2 or 3, and 86.4% for the 22 patients with a CISCUN = 4. These results were confirmed in the independent validation group of 285 patients with similar characteristics. CONCLUSIONS: Patients with chronic hepatitis C and with a CISCUN
A Simple Noninvasive Score Based on Routine Parameters can Predict Liver Cirrhosis in Patients With Chronic Hepatitis
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A Simple Noninvasive Score Based on Routine Parameters can Predict Liver Cirrhosis in Patients With Chronic Hepatitis
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* Acute and chronic improvement in postprandial glucose metabolism by a diet resembling the traditional Mediterranean dietary pattern: Can SCFAs play a role? (49 views)
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Impact Factor: 6.36
View Export to BibTeX Export to EndNote
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* Daily Fructose Traces Intake and Liver Injury in Children with Hereditary Fructose Intolerance (189 views) (PDF 90 views)
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Impact Factor: 4.171
View Export to BibTeX Export to EndNote
Mancini M, Salomone Megna A, Ragucci M, De Luca M, Marino Marsilia G, Nardone G, Coccoli P, Prinster A, Mannelli L, Vergara E, Monti S, Liuzzi R, Incoronato M
* Reproducibility of shear wave elastography (SWE) in patients with chronic liver disease (234 views)
Plosone (ISSN: 1932-6203, 1932-6203electronic, 1932-6203linking), 2017 Oct 12; 12(10): e0185391-e0185391.
Impact Factor: 2.766
View Export to BibTeX Export to EndNote
Filippi M, Boido M, Pasquino C, Garello F, Boffa C, Terreno E
* Successful in vivo MRI tracking of MSCs labeled with Gadoteridol in a Spinal Cord Injury experimental model (277 views)
Exp Neurol (ISSN: 0014-4886), 2016 Aug; 282: 66-77.
Impact Factor: 4.706
View Export to BibTeX Export to EndNote
Mainenti PP, Pizzuti LM, Segreto S, Comerci M, Fronzo SD, Romano F, Crisci V, Smaldone M, Laccetti E, Storto G, Alfano B, Maurea S, Salvatore M, Pace L
* Diffusion volume (DV) measurement in endometrial and cervical cancer: A new MRI parameter in the evaluation of the tumor grading and the risk classification (918 views) (PDF 238 views)
Eur J Radiol (ISSN: 0720-048x, 0720-048xlinking), 2016 Jan; 85(1): 113-124.
Impact Factor: 2.462
View Export to BibTeX Export to EndNote
Lanzillo R, Chiodi A, Carotenuto A, Magri V, Napolitano A, Liuzzi R, Costabile T, Rainone N, Freda MF, Valerio P, Brescia Morra V
* Quality of life and cognitive functions in early onset multiple sclerosis (636 views)
Eur J Paediatr Neuro (ISSN: 1090-3798, 1532-2130), 2016 Jan; 20(1): 158-163.
Impact Factor: 2.013
View Export to BibTeX Export to EndNote
Cella L, Oh JH, Deasy JO, Palma G, Liuzzi R, D'Avino V, Conson M, Picardi M, Salvatore M, Pacelli R
* Predicting radiation-induced valvular heart damage (331 views)
Acta Oncol (ISSN: 0284-186x, 0284-186xlinking), 2015 Mar 24; 54(10): 1796-1804.
Impact Factor: 3.73
View Export to BibTeX Export to EndNote
D'Alterio C, Avallone A, Tatangelo F, Delrio P, Pecori B, Cella L, Pelella A, D'Armiento FP, Carlomagno C, Bianco F, Silvestro L, Pacelli R, Napolitano M, Iaffaioli RV, Scala S
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Impact Factor: 5.085
View Export to BibTeX Export to EndNote
Cella L, Liuzzi R, D'Avino V, Conson M, Di Biase A, Picardi M, Pugliese N, Solla R, Salvatore M, Pacelli R
* Pulmonary damage in Hodgkin's lymphoma patients treated with sequential chemo-radiotherapy: Predictors of radiation-induced lung injury (378 views)
Acta Oncol (ISSN: 0284-186x), 2014 May; 53(5): 613-619.
Impact Factor: 2.997
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De Chiara L, Fagoonee S, Ranghino A, Bruno S, Camussi G, Tolosano E, Silengo L, Altruda F
* Renal cells from spermatogonial germline stem cells protect against kidney injury (354 views)
J Am Soc Nephrol (ISSN: 1046-6673), 2014 Feb; 25(2): 316-328.
Impact Factor: 9.343
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Cella L, Liuzzi R, Conson M, D'Avino V, Salvatore M, Pacelli R
* Multivariate normal tissue complication probability modeling of heart valve dysfunction in Hodgkin lymphoma survivors (405 views)
Int J Radiat Oncol (ISSN: 0360-3016, 1879-355x, 1879-355xelectronic), 2013 Oct 1; 87(2): 304-310.
Impact Factor: 4.176
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Cella L, D'Avino V, Liuzzi R, Conson M, Doria F, Faiella A, Loffredo F, Salvatore M, Pacelli R
* Multivariate normal tissue complication probability modeling of gastrointestinal toxicity after external beam radiotherapy for localized prostate cancer (389 views)
Radiation Oncology (ISSN: 1748-717x), 2013 Sep 23; 8(1): 221-221.
Impact Factor: 2.36
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Maffei E, Midiri M, Russo V, Rengo M, Tedeschi C, Spagnolo P, Seitun S, Francone M, Guaricci AI, Carrabba N, Malagò R, Cuocolo A, Arcadi T, Catalano OA, Cademartiri F
* Rationale, design and methods of CTCA-PRORECAD (Computed Tomography Coronary Angiography Prognostic Registry for Coronary Artery Disease): A multicentre and multivendor registry (332 views)
Radiol Med (ISSN: 0033-8362, 1826-6983, 1826-6983electronic), 2013 Jun; 118(4): 591-607.
Impact Factor: 1.368
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Strianese D, Piscopo R, Elefante A, Napoli M, Comune C, Baronissi I, Liuzzi R, Ferrara M, D'Alessandro A, Ruggiero P, Napolitano P, Grassi P, Iuliano A, Russo C, Brunetti A, Bonavolontà G
* Unilateral Proptosis In Thyroid Eye Disease With Subsequent Contralateral Involvement: Retrospective Follow-Up Study (384 views)
Bmc Ophthalmol (ISSN: 1471-2415), 2013 May 30; 13(1): 21-21.
Impact Factor: 1.075
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Romano S, Staibano S, Greco A, Brunetti A, Nappo G, Ilardi G, Martinelli R, Sorrentino A, Di Pace A, Mascolo M, Bisogni R, Scalvenzi M, Alfano B, Romano M
* FK506 binding protein 51 positively regulates melanoma stemness and metastatic potential (430 views) (PDF 242 views)
Cell Death & (ISSN: 2041-4889, 2041-4889electronic), 2013 Apr 4; 4(6): e578-e578.
Impact Factor: 5.333
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Scalia M, Satriano C, Greca R, Stella AM, Rizzarelli E, Spina-Purrello V
* PARP-1 inhibitors DPQ and PJ-34 negatively modulate proinflammatory commitment of human glioblastoma cells (422 views)
Neurochemical Research (ISSN: 1573-6903, 0364-3190), 2013 Jan; 38(1): 50-58.
Impact Factor: 2.551
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Petretta M, Cuocolo A
In search of a marker of vulnerable carotid plaque: is the key in the heart? (307 views)
Atherosclerosis (ISSN: 1879-1484, 0021-9150), 2012 Jul; 223(1): 95-97.
Impact Factor: 3.706
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Mancini M, Morra VB, Di Donato O, Maglio V, Lanzillo R, Liuzzi R, Salvatore E, Brunetti A, Iaccarino V, Salvatore M
* Multiple sclerosis: cerebral circulation time (403 views)
Radiology (ISSN: 1527-1315, 0033-8419, 1527-1315electronic), 2012 Mar; 262(3): 947-955.
Impact Factor: 6.339
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Pappata S, Santangelo G, Aarsland D, Vicidomini C, Longo K, Bronnick K, Amboni M, Erro R, Vitale C, Caprio MG, Pellecchia MT, Brunetti A, De Michele G, Salvatore M, Barone P
* Mild cognitive impairment in drug-naive patients with PD is associated with cerebral hypometabolism (486 views)
Neurology (ISSN: 0028-3878, 1526-632x, 1526-632xelectronic), 2011 Oct 4; 77(14): 1357-1362.
Impact Factor: 8.312
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Dinacci D, Tessitore A, Russo AA, De Bonis ML, Lavorgna L, Picconi O, Sacco R, Bonavita S, Gallo A, Servillo G, Marcuccio L, Comerci M, Galletti P, Alfano B, Tedeschi G
* BDNF Val66Met polymorphism and brain volumes in multiple sclerosis (437 views) (PDF 233 views)
Neurol Sci (ISSN: 1590-1874, 1590-3478, 1590-1874linking), 2011 Feb; 32(1): 117-123.
Impact Factor: 1.315
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Varnäs K, Nyberg S, Halldin C, Varrone A, Takano A, Karlsson P, Andersson J, McCarthy D, Smith M, Pierson ME, Söderström J, Farde L
* Quantitative analysis of [11C]AZ10419369 binding to 5-HT 1B receptors in human brain (414 views)
J Cereb Blood Flow Metab (ISSN: 0271-678x), 2011 Jan; 31(1): 113-123.
Impact Factor: 5.008
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Storto G, De Renzo A, Pellegrino T, Perna F, De Falco T, Erra P, Nardelli A, Speranza A, Klain M, Rotoli B, Pace L
* Assessment of Metabolic Response to Radioimmunotherapy with (90)Y-Ibritumomab Tiuxetan in Patients with Relapsed or Refractory B-Cell Non-Hodgkin Lymphoma (399 views)
Radiology (ISSN: 0033-8419, 1527-1315, 0033-8419linking), 2010 Jan; 254(1): 245-252.
Impact Factor: 6.069
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Giuffrida ML, Caraci F, Pignataro B, Cataldo S, De Bona P, Bruno V, Molinaro G, Pappalardo G, Messina A, Palmigiano A, Garozzo D, Nicoletti F, Rizzarelli E, Copani A
* Beta-Amyloid Monomers Are Neuroprotective (659 views)
J Neurosci (ISSN: 1529-2401, 0270-6474), 2009 Sep 26; 29(34): 10582-10587.
Impact Factor: 3.669
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Pellecchia MT, Barone PB, Mollica C, Salvatore E, Ianniciello M, Longo K, Varrone A, Vicidomini C, Picillo M, De Michele G, Filla A, Salvatore M, Pappata S
* Diffusion-weighted imaging in multiple system atrophy: a comparison between clinical subtypes (487 views)
Mov Disord (ISSN: 1531-8257, 0885-3185, 0885-3185linking), 2009 Apr 15; 24(5): 689-696.
Impact Factor: 4.014
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Gallotta G, Palmieri V, Piedimonte V, Rendina D, De Bonis S, Russo V, Celentano A, Di Minno M, Postiglione A, Di Minno G
* Increased troponin I predicts in-hospital occurrence of hemodynamic instability in patients with sub-massive or non-massive pulmonary embolism independent to clinical, echocardiographic and laboratory information (317 views)
Int J Cardiol (ISSN: 0167-5273, 1874-1754electronic, 0167-5273linking), 2008 Mar 14; 124(3): 351-357.
Impact Factor: 3.121
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Jovanovic H, Lundberg J, Karlsson P, Cerin A, Saijo T, Varrone A, Halldin C, Nordstrom AL
* Sex differences in the serotonin 1A receptor and serotonin transporter binding in the human brain measured by PET (493 views)
Neuroimage (ISSN: 1053-8119, 1053-8119linking), 2008 Feb 1; 39(3): 1408-1419.
Impact Factor: 5.694
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Migliore T, Parrella LS, Caputi A, Silvestri N, Romano R, Pace L, Imbriaco M, Losi MA, Betocchi S
* Pathogenesis of hypertrophic cardiomyopathy. Impact of growth factors on left ventricular anatomy (367 views)
Minerva Cardioangiol (ISSN: 0026-4725), 2008 Feb; 56(1): 13-20.
Impact Factor: 0.481
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Tedeschi G, Dinacci D, Lavorgna L, Prinster A, Savettieri G, Quattrone A, Livrea P, Messina C, Reggio A, Servillo G, Bresciamorra V, Orefice G, Paciello M, Brunetti A, Paolillo A, Coniglio G, Bonavita S, Di Costanzo A, Bellacosa A, Valentino P, Quarantelli M, Patti F, Salemi G, Cammarata E, Simone I, Salvatore M, Bonavita V, Alfano B
* Correlation between fatigue and brain atrophy and lesion load in multiple sclerosis patients independent of disability (544 views) (PDF 240 views)
J Neurol Sci (ISSN: 0022-510x), 2007 Dec 15; 263(1-2): 15-19.
Impact Factor: 2.315
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Maestri R, Pinna G, Accardo A, Allegrini P, Balocchi R, D'ADDIO G, Ferrario M, Menicucci D, Porta A, Sassi R
* Nonlinear indices of heart rate variability in chronic heart failure patients: Redundancy and comparative clinical value (374 views)
J Cardiovasc Electrophysiol (ISSN: 1045-3873), 2007; 18(4): 425-433.
Impact Factor: 3.475
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Tauchmanovà L, Pivonello R, Di Somma C, Rossi R, De Martino MC, Camera L, Klain M, Salvatore M, Lombardi G, Colao A
* Bone demineralization and vertebral fractures in endogenous cortisol excess: Role of disease etiology and gonadal status (356 views)
J Clin Endocrinol Metab (ISSN: 0021-972x), 2006 May; 91(5): 1779-1784.
Impact Factor: 5.799
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Clemente G, Mancini M, Nazzaro F, Lasorella G, Rivieccio A, Palumbo AM, Rivellese AA, Ferrara L, Giacco R
* Effects of different dairy products on postprandial lipemia (918 views)
Nutrition (ISSN: 0939-4753, 1590-3729electronic), 2003 Dec; 13(6): 377-383.
Impact Factor: 2.148
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Di Somma C, Pivonello R, Loche S, Faggiano A, Klain M, Salvatore M, Lombardi G, Colao A
* Effect of 2 years of cortisol normalization on the impaired bone mass and turnover in adolescent and adult patients with Cushing's disease: A prospective study (459 views)
Clin Endocrinol (ISSN: 0300-0664, 1365-2265, 1365-2265electronic), 2003 Mar; 58(3): 302-308.
Impact Factor: 2.767
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Petretta M, Vicario ML, Spinelli L, Ferro A, Cuocolo A, Condorelli M, Bonaduce D
* Combined effect of the force-frequency and length-tension mechanisms on left ventricular function in patients with dilated cardiomyopathy (315 views)
Eur J Heart Fail European Journal Of Heart Failure (ISSN: 1388-9842), 2002 Dec; 4(6): 727-735.
Impact Factor: 2.134
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Ciampi Q, Betocchi S, Lombardi R, Manganelli F, Storto G, Losi MA, Pezzella E, Finizio F, Cuocolo A, Chiariello M
* Hemodynamic determinants of exercise-induced abnormal blood pressure response in hypertrophic cardiomyopathy (289 views)
Journal Of The American College Of Cardiology (ISSN: 0735-1097), 2002 Jul 17; 40(2): 278-284.
Impact Factor: 6.278
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Manganelli F, Betocchi S, Ciampi Q, Storto G, Losi MA, Violante A, Briguori C, Tocchetti CG, Lombardi R, Cuocolo A, Chiariello M
* Myopia and IOP (416 views)
Ann Ottalmol Clin Ocul, 2002 Jun 15; 115(10): 1053-1058.
Impact Factor: 0
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Molko N, Pappata S, Mangin JF, Poupon C, Vahedi K, Jobert A, LeBihan D, Bousser MG, Chabriat H
* Diffusion tensor imaging study of subcortical gray matter in CADASIL (563 views)
Stroke (ISSN: 0039-2499), 2001 Sep; 32(9): 2049-2054.
Impact Factor: 5.33
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Colao A, Cuocolo A, Di Somma C, Cerbone G, Della Morte A, Pivonello R, Nicolai E, Salvatore M, Lombardi G
Does the age of onset of growth hormone deficiency affect cardiac performance? A radionuclide angiography study (303 views)
Clin Endocrinol (ISSN: 0300-0664, 1365-2265, 1365-2265electronic), 2000 Apr; 52(4): 447-455.
Impact Factor: 2.922
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Longobardi S, Cuocolo A, Merola B, Di Rella F, Colao A, Nicolai E, Cardei S, Salvatore M, Lombardi G
Left ventricular function in young adults with childhood and adulthood onset growth hormone deficiency (434 views)
Clin Endocrinol (ISSN: 0300-0664, 1365-2265, 1365-2265electronic), 1998 Feb; 48(2): 137-143.
Impact Factor: 3.101
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Petretta M, Cuocolo A, Bonaduce D, Nicolai E, Cardei S, Berardino S, Ianniciello A, Apicella C, Bianchi V, Salvatore M
Incremental prognostic value of thallium reinjection after stress- redistribution imaging in patients with previous myocardial infarction and left ventricular dysfunction (329 views)
J Nucl Med (ISSN: 0161-5505, 1535-5667, 1535-5667electronic), 1997 Feb; 38(2): 195-200.
Impact Factor: 3.491
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Marcassa C, Galli M, Cuocolo A, Scappellato F, Maurea S, Salvatore M
Rest-redistribution thallium-201 and rest technetium-99m-sestamibi SPECT in patients with stable coronary artery disease and ventricular dysfunction (286 views)
J Nucl Med (ISSN: 0161-5505, 1535-5667, 1535-5667electronic), 1997; 38(3): 419-424.
Impact Factor: 3.491
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Ferraro S, Cuocolo A, Nappi A, Trimigliozzi P, D'Alto M, Storto G, Sullo P, Salvatore M, Chiariello M
The short- and medium-term ambulatory radionuclide study of left ventricular function (VEST) after aortocoronary bypass (212 views)
Cardiologia (ISSN: 0393-1978), 1995 Sep; 40(9): 659-665.
Impact Factor: 0
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Miletich RS, Bankiewicz KS, Quarantelli M, Plunkett RJ, Frank J, Kopin IJ, Di Chiro G
MRI detects acute degeneration of the nigrostriatal dopamine system after MPTP exposure in hemiparkinsonian monkeys (334 views)
Ann Neurol (ISSN: 0364-5134), 1994 Jun; 35(6): 689-697.
Impact Factor: 9.513
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Cuocolo A, Nappi A, Nicolai E, Pace L, Imbriaco M, Morisco C, Chiariello M, Trimarco B, Salvatore M
Ambulatory monitoring of left ventricular function: the assessment of transient episodes of ventricular dysfunction in patients with ischemic cardiopathy (347 views)
G Ital Cardiol (ISSN: 0046-5968), 1992; 22(7): 813-824.
Impact Factor: 0
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Testino G, Leone S, Fagoonee S, Del Bas JM, Rodriguez B, Puiggros F, Marine S, Rodriguez MA, Morina D, Armengol L, Caimari A, Arola L, Cimini FA, Barchetta I, Carotti S, Bertoccini L, Baroni MG, Vespasiani-gentilucci U, Cavallo MG, Morini S, Nelson JE, Roth CL, Wilson LA, Yates KP, Aouizerat B, Morgan-stevenson V, Whalen E, Hoofnagle A, Mason M, Gersuk V, Yeh MM, Kowdley KV, Lee SM, Jun DW, Cho YK, Jang KS, Kucukazman M, Ata N, Dal K, Yeniova AO, Kefeli A, Basyigit S, Aktas B, Akin KO, Agladioglu K, Ure OS, Topal F, Nazligul Y, Beyan E, Ertugrul DT, Catena C, Cosma C, Camozzi V, Plebani M, Ermani M, Sechi LA, Fallo F, Goto Y, Ray MB, Mendenhall CL, French SW, Gartside PS
Serum vitamin A deficiency and increased intrahepatic expression of cytokeratin antigen in alcoholic liver disease (600 views)
Hepatology (ISSN: 1827-1669electronic, 0026-4806linking), 1988 Sep; 83120693611123109(5): 1019-1026.
Impact Factor: 0.913
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44 Records (42 excluding Abstracts).
Total impact factor: 161.901 (147.225 excluding Abstracts).
Total 5 year impact factor: 179.147 (164.193 excluding Abstracts).
Total impact factor: 161.901 (147.225 excluding Abstracts).
Total 5 year impact factor: 179.147 (164.193 excluding Abstracts).
333 views. Last view on Saturday 11 March 2023, 14:05:38
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