Evaluation of LiF: Mg, Ti (TLD-100) for Intraoperative Electron Radiation Therapy Quality Assurance(335 views) Liuzzi R, Savino F, D'Avino V, Pugliese M, Cella L
Plosone (ISSN: 1932-6203, 1932-6203electronic, 1932-6203linking), 2015 Oct 1; 10(10): e0139287-e0139287.
Institute of Biostructure and Bioimaging, National Research Council (CNR), Naples, Italy., Department of Physics, Federico II University, Naples, Italy.,
References: Not available.
Evaluation of LiF: Mg, Ti (TLD-100) for Intraoperative Electron Radiation Therapy Quality Assurance
BACKGROUND: Purpose of the present work was to investigate thermoluminescent dosimeters (TLDs) response to intraoperative electron radiation therapy (IOERT) beams. In an IOERT treatment, a large single radiation dose is delivered with a high dose-per-pulse electron beam (2-12 cGy/pulse) during surgery. To verify and to record the delivered dose, in vivo dosimetry is a mandatory procedure for quality assurance. The TLDs feature many advantages such as a small detector size and close tissue equivalence that make them attractive for IOERT as in vivo dosimeters. METHODS: LiF:Mg,Ti dosimeters (TLD-100) were irradiated with different IOERT electron beam energies (5, 7 and 9 MeV) and with a 6 MV conventional photon beam. For each energy, the TLDs were irradiated in the dose range of 0-10 Gy in step of 2Gy. Regression analysis was performed to establish the response variation of thermoluminescent signals with dose and energy. RESULTS: The TLD-100 dose-response curves were obtained. In the dose range of 0-10 Gy, the calibration curve was confirmed to be linear for the conventional photon beam. In the same dose region, the quadratic model performs better than the linear model when high dose-per-pulse electron beams were used (F test; p<0.05). CONCLUSIONS: This study demonstrates that the TLD dose response, for doses
Evaluation of LiF: Mg, Ti (TLD-100) for Intraoperative Electron Radiation Therapy Quality Assurance