Keywords: 18f-Dpa-714, Sod1g93a, Tspo, Mice, Pet Ct, Carrier Protein, N Diethyl 2 [2 (4 (2fluoroethoxy)phenyl) 5, 7 Dimethylpyrazolo[1, 5 A]pyrimidin 3 Yl]acetamide F 18, Tracer, Translocator Protein 18, Unclassified Drug, 4 Aminobutyric Acid Receptor, Bzrp Protein, Mouse, N-Diethyl-2-(2-(4-(2-Fluoroethoxy)phenyl)-5, 7-Dimethylpyrazolo(1, 5-A)pyrimidin-3-Yl)acetamide, Pyrazole Derivative, Pyrimidine Derivative, Amyotrophic Lateral Sclerosis, Animal Care, Animal Experiment, Animal Model, Article, Association Cortex, Body Constitution, Body Weight, Brain Stem, Cervical Spinal Cord, Computer Assisted Emission Tomography, Controlled Study, Frontal Cortex, Histocompatibility Complex, Immunofluorescence, Immunohistochemistry, Motor Cortex, Neuroimaging, Nonhuman, Protein Expression, Diagnostic Imaging, Disease Model, Gene Expression Regulation, Metabolism, Positron Emission Tomography-Computed Tomography, Transport At The Cellular Level, Biological Transport, Positron Emission Tomography Computed Tomography, Gaba, Amyotrophic Lateral Sclerosis Diagnostic Imaging Metabolism
, Brain Diagnostic Imaging Metabolism
, Pyrazoles Metabolism
, Pyrimidines Metabolism
, Gaba Metabolism,
Affiliations: *** IBB - CNR ***
Institute of Biostructure and Bioimaging, National Research Council, Via T. De Amicis 95, 80145, Naples, Italy., Ceinge Biotecnologie Avanzate s. c. a r. l., Via G. Salvatore 486, 80145, Naples, Italy., IRCCS SDN, Via E. Gianturco 113, 80143, Naples, Italy., Department of Advanced Biomedical Sciences, University "Federico II", Via S. Pansini 5, 80131, Naples, Italy., Division of Pharmacology, Department of Neuroscience, Reproductive and Dentistry Sciences, School of Medicine, University "Federico II", Via S. Pansini 5, 80131, Naples, Italy., CEA, Institute for Biomedical Imaging, 4 Place du General Leclerc, 91401, Orsay, France., Institute of Biostructure and Bioimaging, National Research Council, Via T. De Amicis 95, 80145, Naples, Italy. sabina.pappata@ibb.cnr.it.,
Ceinge Biotecnologie Avanzate s. c. a r. l., Via G. Salvatore 486, 80145, Naples, Italy.
IRCCS SDN, Via E. Gianturco 113, 80143, Naples, Italy.
Department of Advanced Biomedical Sciences, University "Federico II", Via S. Pansini 5, 80131, Naples, Italy.
Division of Pharmacology, Department of Neuroscience, Reproductive and Dentistry Sciences, School of Medicine, University "Federico II", Via S. Pansini 5, 80131, Naples, Italy.
CEA, Institute for Biomedical Imaging, 4 Place du Général Leclerc, 91401, Orsay, France.
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Imaging of brain TSPO expression in a mouse model of amyotrophic lateral sclerosis with (18)F-DPA-714 and micro-PET/CT