Eco-friendly microwave-assisted protocol to prepare hyaluronan-fatty acid conjugates and to induce their self-assembly process
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Eco-friendly microwave-assisted protocol to prepare hyaluronan-fatty acid conjugates and to induce their self-assembly process (476 views)

Calce E, Mercurio F, Leone M, Saviano M, De Luca S

Carbohyd Polym (ISSN: 0144-8617), 2016 Feb; 143: 84-89.

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Paper type: Journal Article

Impact factor: 4.811, 5-year impact factor: 5.13

Url: https://www2.scopus.com/inward/record.uri?eid=2-s2.0-84961655051&partnerID=40&md5=6254d7a7c72598f7e4a72f09cb2baf4f

Keywords: Biocompatible Process, Hyaluronan-Based Material, Microwave Activation, Nanoparticle Preparation, Renewable Sources, Solvent-Free Synthesis

Affiliations:
*** IBB - CNR ***

Institute of Biostructures and Bioimaging, National Research Council, Naples, Italy
Institute of Crystallography, National Research Council, Bari, Italy


References:
Not available.
Eco-friendly microwave-assisted protocol to prepare hyaluronan-fatty acid conjugates and to induce their self-assembly process

An environmentally sustainable and energy-efficient synthetic process has been developed to prepare hyaluronan-based nano-sized material. It consists in a microwave-promoted acylation of the hydroxyl function of the polysaccharide with natural fatty acids, performed under solvent-free conditions. The efficient interaction of the solid reagents with the MW radiation accounts for the obtained high yielded products. The self-assembly process of the obtained compounds very fast occurred in an aqueous medium under MW-radiation, thus allowing the development of a green protocol for the nano-particles preparation. © 2016 Elsevier Ltd. All rights reserved.
Eco-friendly microwave-assisted protocol to prepare hyaluronan-fatty acid conjugates and to induce their self-assembly process

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Eco-friendly microwave-assisted protocol to prepare hyaluronan-fatty acid conjugates and to induce their self-assembly process

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Calce E, Ringhieri P, Mercurio FA, Leone M, Bugatti V, Saviano M, Vittoria V, De Luca S
* A biocompatible process to prepare hyaluronan-based material able to self-assemble into stable nano-particles (502 views)
Rsc Adv (ISSN: 2046-2069, 2046-2069electronic), 2015; 5(37): 29573-29576.
Impact Factor: 3.289
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1 Records (1 excluding Abstracts).
Total impact factor: 3.289 (3.289 excluding Abstracts).
Total 5 year impact factor: 3.485 (3.485 excluding Abstracts).

Last modified by Marco Comerci on Tuesday 09 April 2024, 12:56:55
476 views. Last view on Tuesday 10 December 2024, 9:02:01