Impact of obesity and acquisition protocol on (123)I-metaiodobenzylguanidine indexes of cardiac sympathetic innervation (677 views)
Quant Imaging Med Surg (ISSN: 2223-4292print, 2223-4306linking), 2015 Dec; 5(6): 822-828.
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Paper type: Journal Article,
Impact factor: 3.105, 5-year impact factor: 3.545
Url: Not available.
Keywords: Metaiodobenzylguanidine Cardiac Imaging (mibg Cardiac Imaging), Heart-To-Mediastinum Ratios (h, Obesity, Prone-Position Acquisition, Washout Rate,
Affiliations:
*** IBB - CNR ***
1 Institute of Biostructure and Bioimaging, National Council of Research, Via De Amicis 95, 80145 Naples, Italy ; 2 Department of Advanced Biomedical Sciences, 3 Department of Translational Medical Sciences, University Federico II, Via Pansini 5, 80131 Naples, Italy.,
References:
Not available.
Quant Imaging Med Surg (ISSN: 2223-4292print, 2223-4306linking), 2015 Dec; 5(6): 822-828.
Export to BibTeX Export to EndNote
Paper type: Journal Article,
Impact factor: 3.105, 5-year impact factor: 3.545
Url: Not available.
Keywords: Metaiodobenzylguanidine Cardiac Imaging (mibg Cardiac Imaging), Heart-To-Mediastinum Ratios (h, Obesity, Prone-Position Acquisition, Washout Rate,
Affiliations:
*** IBB - CNR ***
1 Institute of Biostructure and Bioimaging, National Council of Research, Via De Amicis 95, 80145 Naples, Italy ; 2 Department of Advanced Biomedical Sciences, 3 Department of Translational Medical Sciences, University Federico II, Via Pansini 5, 80131 Naples, Italy.,
References:
Not available.
Impact of obesity and acquisition protocol on (123)I-metaiodobenzylguanidine indexes of cardiac sympathetic innervation
BACKGROUND: This study was designed to assess the impact of obesity and acquisition protocol on (123)I-metaiodobenzylguanidine (MIBG) indexes of cardiac sympathetic innervation. METHODS: Forty-five patients with heart failure (HF) (38 men, age 58+/-15 years) underwent (123)I-MIBG cardiac imaging. Of these patients, 10 were obese [body mass index (BMI) >/=30 kg/m(2)]. Ten-minute planar images of the thorax in anterior view were performed 15 minutes ("early" image) and 3 hours and 50 minutes ("late" image) after tracer administration in both supine- and prone-position. Early and late (123)I-MIBG heart-to-mediastinum (H/M) ratios and washout rate were computed. RESULTS: In overall study population, early and late (123)I-MIBG H/M ratios and washout rate were comparable between supine- and prone-position acquisitions. Obese patients had a lower early and late (123)I-MIBG H/M ratios both in supine (P<0.01) and prone (P<0.05) positions compared to non-obese subjects. CONCLUSIONS: Our results indicate that in HF patients, obesity has a significant impact on (123)I-MIBG indexes of cardiac sympathetic innervation. Prone-position did not change early and late (123)I-MIBG H/M ratios and washout rate compared to supine position both in obese and non-obese HF patients.
BACKGROUND: This study was designed to assess the impact of obesity and acquisition protocol on (123)I-metaiodobenzylguanidine (MIBG) indexes of cardiac sympathetic innervation. METHODS: Forty-five patients with heart failure (HF) (38 men, age 58+/-15 years) underwent (123)I-MIBG cardiac imaging. Of these patients, 10 were obese [body mass index (BMI) >/=30 kg/m(2)]. Ten-minute planar images of the thorax in anterior view were performed 15 minutes ("early" image) and 3 hours and 50 minutes ("late" image) after tracer administration in both supine- and prone-position. Early and late (123)I-MIBG heart-to-mediastinum (H/M) ratios and washout rate were computed. RESULTS: In overall study population, early and late (123)I-MIBG H/M ratios and washout rate were comparable between supine- and prone-position acquisitions. Obese patients had a lower early and late (123)I-MIBG H/M ratios both in supine (P<0.01) and prone (P<0.05) positions compared to non-obese subjects. CONCLUSIONS: Our results indicate that in HF patients, obesity has a significant impact on (123)I-MIBG indexes of cardiac sympathetic innervation. Prone-position did not change early and late (123)I-MIBG H/M ratios and washout rate compared to supine position both in obese and non-obese HF patients.
Impact of obesity and acquisition protocol on (123)I-metaiodobenzylguanidine indexes of cardiac sympathetic innervation
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Impact of obesity and acquisition protocol on (123)I-metaiodobenzylguanidine indexes of cardiac sympathetic innervation
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De Rosa A, Pappata S, Pellegrino T, De Leva MF, Maddaluno G, Fiumara G, Carotenuto R, Petretta M, Filla A, De Michele G, Cuocolo A
* Reduced Cardiac 123i-Metaiodobenzylguanidine Uptake In Patients With Spinocerebellar Ataxia Type 2: A Comparative Study With Parkinson'S Disease (1024 views)
Eur J Nucl Med (ISSN: 1619-7089, 1619-7070, 0340-6997), 2013 Dec; 40(12): 1914-1921.
Impact Factor: 2.692
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* Reduced Cardiac 123i-Metaiodobenzylguanidine Uptake In Patients With Spinocerebellar Ataxia Type 2: A Comparative Study With Parkinson'S Disease (1024 views)
Eur J Nucl Med (ISSN: 1619-7089, 1619-7070, 0340-6997), 2013 Dec; 40(12): 1914-1921.
Impact Factor: 2.692
View Export to BibTeX Export to EndNote
1 Records (1 excluding Abstracts).
Total impact factor: 2.692 (2.692 excluding Abstracts).
Total 5 year impact factor: 3.983 (3.983 excluding Abstracts).
Total impact factor: 2.692 (2.692 excluding Abstracts).
Total 5 year impact factor: 3.983 (3.983 excluding Abstracts).
677 views. Last view on Sunday 27 April 2025, 23:13:35
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