Effect of cisplatin containing liposomes formulated by unsaturated chain-containing lipids on gynecological tumor cells
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Effect of cisplatin containing liposomes formulated by unsaturated chain-containing lipids on gynecological tumor cells
(
337 views
)
Ringhieri P, Pannunzio A, Boccarelli A,
Morelli G
, Coluccia M,
Tesauro D
J Liposome Res (ISSN: 0898-2104)
,
2016;
N/D: 1-6.
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Paper type:
Journal Article,
Impact factor:
1.971,
5-year impact factor:
2.038
Url:
https://www2.scopus.com/inward/record.uri?eid=2-s2.0-84958039992&partnerID=40&md5=1e546c8bb56a0425795098d212649968
Keywords:
Cddp, Cisplatin, Drug Delivery, Gynecological Tumors, Liposomes,
Affiliations:
*** IBB - CNR ***
Department of Pharmacy and CIRPeB, University of Naples “Federico II”, Naples, Italy
Istituto Di Biostrutture E Bioimmagini – CNR, Naples, Italy
References:
Not available.
Effect of cisplatin containing liposomes formulated by unsaturated chain-containing lipids on gynecological tumor cells
Gynecological tumors are major therapeutic areas of platinum-based anticancer drugs. Here, we report the characterization and in vitro biological assays of cisplatin-containing Egg L-α-phosphatidylcholine liposomes with different amounts of cholesterol. Dynamic light scattering estimated sizes of all obtained liposomes in the 100 nm range that are suitable for in vivo use. On the basis of these data and of the drug loading values, the best formulation has been selected. Stability and drug release properties of platinum-containing liposomes have been verified in serum. The growth inhibitory effects of both liposomal and free drug in a panel of ovarian and breast human cancer cell lines, characterized by a different drug sensitivity, give comparable or better results with respect to free cisplatin drug. © 2016 Taylor & Francis
Effect of cisplatin containing liposomes formulated by unsaturated chain-containing lipids on gynecological tumor cells
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Targeted Drug Delivery by integrin avb3 antagonist
Panico Mariarosaria
Zaccaro Laura
Zannetti Antonella
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Chemical modification of natural molecules, such as peptides and polysaccharides, to be employed as therapeutic agents as well as sensor diagnostic tools
De Luca Stefania
▼
Biomolecular NMR: structural studies of proteins and peptides and drug discovery applications
Maglio Ornella
Diana Donatella
Leone Marilisa
Effect of cisplatin containing liposomes formulated by unsaturated chain-containing lipids on gynecological tumor cells
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1653 views
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Curr Med Chem (ISSN: 0929-8673, 1875-533x, 1875-533xelectronic)
,
2009 Mar;
16(7): 780-795.
Impact Factor:
4.708
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Accardo A
,
Tesauro D
,
Morelli G
, Del Pozzo L,
Pedone C
, Tornesello AL, Benedetti E
*
Supramolecular aggregates derivatized by CCK8 peptide as selective nanocarriers for drug delivery
(
443 views
)
Adv Exp Med Biol (ISSN: 0065-2598, 0065-2598print)
,
2009;
611: 603-604.
Impact Factor:
2.02
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Marasco D
, Perretta G, Sabatella M,
Ruvo M
*
Past and Future Perspectives of Synthetic Peptide Libraries
(
747 views
)
Curr Protein Pept Sci (ISSN: 1389-2037, 1389-2037linking)
,
2008 Oct;
9(5): 447-467.
Impact Factor:
3.011
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Accardo A
,
Tesauro D
, Aloj L, Tarallo L, Arra C, Mangiapia G, Vaccaro M,
Pedone C
, Paduano L,
Morelli G
*
Peptide-containing aggregates as selective nanocarriers for therapeutics
(
490 views
)
Chemmedchem (ISSN: 1860-7179, 1860-7187, 1860-7187electronic)
,
2008 Apr;
3(4): 594-602.
Impact Factor:
3.15
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Zeni O,
Palumbo R
, Bernini R, Zeni L, Sarti M, Scarfi MR
*
Cytotoxicity investigation on cultured human blood cells treated with single-wall carbon nanotubes
(
446 views
)
Sensors (ISSN: 1424-3210, 1424-8220, 1424-8220electronic)
,
2008 Jan;
8(1): 488-499.
Impact Factor:
1.87
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Maggi A,
Salvatore M
Molecular imaging
(
378 views
)
Q J Nucl Med Mol Im (ISSN: 1824-4785, 1824-4478, 1824-4785linking)
,
2007 Jun;
51(2): 95-95.
Impact Factor:
1.724
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Del Vecchio S
,
Zannetti A
,
Fonti R
, Pace L,
Salvatore M
*
Nuclear imaging in cancer theranostics
(
844 views
)
Q J Nucl Med Mol Im (ISSN: 1824-4785, 1824-4478, 1824-4785linking)
,
2007 Jun;
51(2): 152-163.
Impact Factor:
1.724
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Accardo A
,
Tesauro D
, Mangiapia G,
Pedone C
,
Morelli G
*
Nanostructures by self-assembling peptide amphiphile as potential selective drug carriers
(
554 views
)
Biopolymers (ISSN: 0006-3525, 0006-6352, 0006-3525print)
,
2007;
88(2): 115-121.
Impact Factor:
2.389
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Pappalardo M, Milardi D, Grasso D, La Rosa C
*
Phase behaviour of polymer-grafted DPPC membranes for drug delivery systems design
(
459 views
)
Journal Of Thermal Analysis And Calorimetry (ISSN: 1388-6150)
,
2005 May;
80(2): 413-418.
Impact Factor:
1.425
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Cortesi R, Mischiati C, Borgatti M, Breda L,
Romanelli A
, Saviano M,
Pedone C
, Gambari R, Nastruzzi C
*
Formulations for natural and peptide nucleic acids based on cationic polymeric submicron particles
(
473 views
)
The Aaps Journal (ISSN: 1522-1059, 1550-7416)
,
2004 Jan 20;
6(1): N/D-N/D.
Impact Factor:
1.938
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Borgatti M, Breda L, Cortesi R, Nastruzzi C,
Romanelli A
, Saviano M, Bianchi N, Mischiati C,
Pedone C
, Gambari R
*
Cationic Liposomes As Delivery Systems For Double-Stranded Pna-Dna Chimeras Exhibiting Decoy Activity Against Nf-Kappab Transcription Factors
(
576 views
)
Biochem Pharmacol Biochemical Pharmacology (ISSN: 1873-2968, 0006-2952)
,
2002 Sep 15;
64(4): 609-616.
Impact Factor:
3.542
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58
Records (
54
excluding Abstracts).
Total impact factor:
196.793
(
185.638
excluding Abstracts).
Total 5 year impact factor:
193.193
(
177.722
excluding Abstracts).
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