Altered processing of rewarding and aversive basic taste stimuli in symptomatic women with anorexia nervosa and bulimia nervosa: An fMRI study (263 views)
J Psychiatr Res (ISSN: 0022-3956), 2017 Feb 21; 90: 94-101.
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Paper type: Journal Article,
Impact factor: 4, 5-year impact factor: 4.437
Url: https://www.scopus.com/inward/record.uri?eid=2-s2.0-85013944232&doi=10.1016%2fj.jpsychires.2017.02.013&partnerID=40&md5=069c2ef479de3467c8bfe702fe86292b
Keywords: Anorexia Nervosa, Bulimia Nervosa, Disgust, Reward, Taste, Fmri,
Affiliations:
*** IBB - CNR ***
Department of Psychiatry, University of Naples SUN, Naples, Italy., Department of Psychiatry, University of Naples SUN, Naples, Italy; Department of Medicine, Surgery and Dentistry "Scuola Medica Salernitana", Section of Neurosciences, University of Salerno, Salerno, Italy. Electronic address: monteri@tin.it., Department of Medicine, Surgery and Dentistry "Scuola Medica Salernitana", Section of Neurosciences, University of Salerno, Salerno, Italy., Biostructure and Bioimaging Institute, National Research Council, Naples, Italy., Department of Neuroscience, Reproductive and Dentistry Science, ENT Unit; "Federico II" University, Naples, Italy., Department of Mental Health, A.S.L. NA1, Naples, Italy., IRCCS SDN Istituto di Ricerca, Naples, Italy.,
References:
Not available.
J Psychiatr Res (ISSN: 0022-3956), 2017 Feb 21; 90: 94-101.
Export to BibTeX Export to EndNote
Paper type: Journal Article,
Impact factor: 4, 5-year impact factor: 4.437
Url: https://www.scopus.com/inward/record.uri?eid=2-s2.0-85013944232&doi=10.1016%2fj.jpsychires.2017.02.013&partnerID=40&md5=069c2ef479de3467c8bfe702fe86292b
Keywords: Anorexia Nervosa, Bulimia Nervosa, Disgust, Reward, Taste, Fmri,
Affiliations:
*** IBB - CNR ***
Department of Psychiatry, University of Naples SUN, Naples, Italy., Department of Psychiatry, University of Naples SUN, Naples, Italy; Department of Medicine, Surgery and Dentistry "Scuola Medica Salernitana", Section of Neurosciences, University of Salerno, Salerno, Italy. Electronic address: monteri@tin.it., Department of Medicine, Surgery and Dentistry "Scuola Medica Salernitana", Section of Neurosciences, University of Salerno, Salerno, Italy., Biostructure and Bioimaging Institute, National Research Council, Naples, Italy., Department of Neuroscience, Reproductive and Dentistry Science, ENT Unit; "Federico II" University, Naples, Italy., Department of Mental Health, A.S.L. NA1, Naples, Italy., IRCCS SDN Istituto di Ricerca, Naples, Italy.,
References:
Not available.
Altered processing of rewarding and aversive basic taste stimuli in symptomatic women with anorexia nervosa and bulimia nervosa: An fMRI study
Functional magnetic resonance imaging (fMRI) studies have displayed a dysregulation in the way in which the brain processes pleasant taste stimuli in patients with anorexia nervosa (AN) and bulimia nervosa (BN). However, exactly how the brain processes disgusting basic taste stimuli has never been investigated, even though disgust plays a role in food intake modulation and AN and BN patients exhibit high disgust sensitivity. Therefore, we investigated the activation of brain areas following the administration of pleasant and aversive basic taste stimuli in symptomatic AN and BN patients compared to healthy subjects. Twenty underweight AN women, 20 symptomatic BN women and 20 healthy women underwent fMRI while tasting 0.292 M sucrose solution (sweet taste), 0.5 mM quinine hydrochloride solution (bitter taste) and water as a reference taste. In symptomatic AN and BN patients the pleasant sweet stimulus induced a higher activation in several brain areas than that induced by the aversive bitter taste. The opposite occurred in healthy controls. Moreover, compared to healthy controls, AN patients showed a decreased response to the bitter stimulus in the right amygdala and left anterior cingulate cortex, while BN patients showed a decreased response to the bitter stimulus in the right amygdala and left insula. These results show an altered processing of rewarding and aversive taste stimuli in ED patients, which may be relevant for understanding the pathophysiology of AN and BN.
Functional magnetic resonance imaging (fMRI) studies have displayed a dysregulation in the way in which the brain processes pleasant taste stimuli in patients with anorexia nervosa (AN) and bulimia nervosa (BN). However, exactly how the brain processes disgusting basic taste stimuli has never been investigated, even though disgust plays a role in food intake modulation and AN and BN patients exhibit high disgust sensitivity. Therefore, we investigated the activation of brain areas following the administration of pleasant and aversive basic taste stimuli in symptomatic AN and BN patients compared to healthy subjects. Twenty underweight AN women, 20 symptomatic BN women and 20 healthy women underwent fMRI while tasting 0.292 M sucrose solution (sweet taste), 0.5 mM quinine hydrochloride solution (bitter taste) and water as a reference taste. In symptomatic AN and BN patients the pleasant sweet stimulus induced a higher activation in several brain areas than that induced by the aversive bitter taste. The opposite occurred in healthy controls. Moreover, compared to healthy controls, AN patients showed a decreased response to the bitter stimulus in the right amygdala and left anterior cingulate cortex, while BN patients showed a decreased response to the bitter stimulus in the right amygdala and left insula. These results show an altered processing of rewarding and aversive taste stimuli in ED patients, which may be relevant for understanding the pathophysiology of AN and BN.
Altered processing of rewarding and aversive basic taste stimuli in symptomatic women with anorexia nervosa and bulimia nervosa: An fMRI study
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Altered processing of rewarding and aversive basic taste stimuli in symptomatic women with anorexia nervosa and bulimia nervosa: An fMRI study
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* Cortical thickness, local gyrification index and fractal dimensionality in people with acute and recovered Anorexia Nervosa and in people with Bulimia Nervosa (92 views)
Psychiatry Res Neuroimaging (ISSN: 0925-4927linking), 2020 May 30; 299: 111069-111069.
Impact Factor: 2.063
View Export to BibTeX Export to EndNote
Canna A, Prinster A, Monteleone AM, Cantone E, Monteleone P, Volpe U, Maj M, Di Salle F, Esposito F
* Interhemispheric Functional Connectivity in Anorexia and Bulimia Nervosa (327 views)
Eur J Neurosci (ISSN: 0953-816x), 2017 May; 45(9): 1129-1140.
Impact Factor: 2.832
View Export to BibTeX Export to EndNote
Monteleone AM, Monteleone P, Esposito F, Prinster A, Ruzzi V, Canna A, Aiello M, Di Salle F, Maj M
* The Effects of Childhood Maltreatment on Brain Structure in Adults with Eating Disorders (439 views)
World J Biol Psychia (ISSN: 1562-2975), 2017; N/D: 1-26.
Impact Factor: 3.713
View Export to BibTeX Export to EndNote
Pasanisi F, Pace L, Fonti R, Marra M, Sgambati D, De Caprio C, De Filippo E, Vaccaro A, Salvatore M, Contaldo F
* Evidence of brown fat activity in constitutional leanness (598 views)
J Clin Endocrinol Metab (ISSN: 1945-7197, 0021-972x, 0021-972xlinking), 2013 Mar; 98(3): 1214-1218.
Impact Factor: 6.31
View Export to BibTeX Export to EndNote
De Simone G, Di Fiore A, Supuran CT
* Are carbonic anhydrase inhibitors suitable for obtaining antiobesity drugs? (579 views)
Curr Pharm Des Current Pharmaceutical Design (ISSN: 1381-6128, 1873-4286), 2008 Mar; 14(7): 655-660.
Impact Factor: 4.399
View Export to BibTeX Export to EndNote
5 Records (5 excluding Abstracts).
Total impact factor: 19.317 (19.317 excluding Abstracts).
Total 5 year impact factor: 17.814 (17.814 excluding Abstracts).
Total impact factor: 19.317 (19.317 excluding Abstracts).
Total 5 year impact factor: 17.814 (17.814 excluding Abstracts).
263 views. Last view on Thursday 12 September 2024, 10:26:15
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