Thyroid Cancer in the Pediatric Age in Sicily: Influence of the Volcanic Environment(502 views) Russo M, Malandrino P, Moleti M, D'Angelo A, Tavarelli M, Sapuppo G, Giani F, Richiusa P, Squatrito S, Vigneri R, Pellegriti G
Anticancer Res (ISSN: 0250-7005, 0250-0700, 0250-7005linking), 2017 Mar; 37(3): 1515-1522.
Department of Clinical and Experimental Medicine, University of Messina, Messina, Italy., Endocrinology, Department of Clinical and Experimental Medicine, University of Catania, Garibaldi-Nesima Medical Center, Catania, Italy., Endocrinology, Di.Bi.M.I.S University of Palermo, Palermo, Italy., Endocrinology, Department of Clinical and Experimental Medicine, University of Catania, Garibaldi-Nesima Medical Center, Catania, Italy vigneri@unict.it., Institute of Biostructures and Bioimaging, CNR, Catania, Italy.,
Endocrinology, Department of Clinical and Experimental Medicine, University of Catania, Garibaldi-Nesima Medical Center, Catania, Italy.
Endocrinology, Di.Bi.M.I.S University of Palermo, Palermo, Italy.
Institute of Biostructures and Bioimaging, CNR, Catania, Italy.
References: Not available.
Thyroid Cancer in the Pediatric Age in Sicily: Influence of the Volcanic Environment
BACKGROUND/AIM: Pediatric thyroid cancer (TC) is rare but its incidence is increasing. We analyzed incidence and characteristics of pediatric TC in Sicily and comparatively evaluated data from the volcanic and non-volcanic areas. MATERIALS AND METHODS: All incident pediatric (0-19 years) TCs in Sicily between 2002-2009 were analyzed for the area of residence and compared to data for adults. RESULTS: A total of 54 differentiated TCs (DTC) and nine medullary TCs were diagnosed in Sicily in children between 2002-2009. DTC age standardized rate for the world population (ASRw) was 0.8/10(5) in females and 0.2/10(5) in males, with a higher incidence in the volcanic area (ASRw=1.4/10(5) in females, 0.5/10(5) in males) vs. the rest of Sicily (ASRw=0.6/10(5) in females, 0.1/10(5) in males). Pediatric TCs were larger in size and more frequently with extrathyroid extension and lymph-node involvement in comparison to TCs in adults. CONCLUSION: In the volcanic environment of Sicily, TC incidence is markedly increased in children, suggesting a short-term effect of unidentified carcinogens of volcanic origin.
Thyroid Cancer in the Pediatric Age in Sicily: Influence of the Volcanic Environment
No results.
Thyroid Cancer in the Pediatric Age in Sicily: Influence of the Volcanic Environment
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