Comparison of left ventricular shape by gated SPECT imaging in diabetic and nondiabetic patients with normal myocardial perfusion: A propensity score analysis (592 views)
J Nucl Cardiol (ISSN: 1071-3581, 1532-6551, 1532-6551electronic), 2017 Aug 14; 25(2): 394-403.
Export to BibTeX Export to EndNote
Paper type: Journal Article,
Impact factor: 4.011, 5-year impact factor: 3.456
Url: https://www.scopus.com/inward/record.uri?eid=2-s2.0-85028568975&doi=10.1007%2fs12350-017-1009-6&partnerID=40&md5=6a222d8d60e9f43cf6e5d83e98e647df
Keywords: Diabetes Mellitus, Cardiovascular Risk Factors, Gated Spect, Left Ventricular Shape Index, Adult, Article, Body Mass, Cardiac Gated Imaging, Cohort Analysis, Controlled Study, Coronary Artery Disease, Coronary Risk, Diabetic Patient, Female, Gated Single Photon Emission Computed Tomography, Heart Left Ventricle Ejection Fraction, Heart Left Ventricle Enddiastolic Volume, Heart Left Ventricle Endsystolic Volume, Heart Muscle Perfusion, Human, Hypercholesterolemia, Hypertension, Major Clinical Study, Middle Aged, Priority Journal, Propensity Score, Stress Radiography,
Affiliations:
*** IBB - CNR ***
Department of Advanced Biomedical Sciences, University Federico II, Via Pansini 5, 80131, Naples, Italy., Institute of Biostructure and Bioimaging, National Council of Research, Naples, Italy., Department of Translational Medical Sciences, University Federico II, Naples, Italy., Department of Medicine, Cedars-Sinai Medical Center, Los Angeles, CA, USA., David Geffen School of Medicine, UCLA, Los Angeles, CA, USA., Department of Advanced Biomedical Sciences, University Federico II, Via Pansini 5, 80131, Naples, Italy. cuocolo@unina.it.,
References:
Koitabashi, N., Kass, D.A., Reverse remodeling in heart failure-mechanisms and therapeutic opportunities (2011) Nat Rev Cardiol, 9, pp. 147-157. , PID: 2214307
Heusch, G., Libby, P., Gersh, B., Yellon, D., Böhm, M., Lopaschuk, G., Cardiovascular remodelling in coronary artery disease and heart failure (2014) Lancet, 383, pp. 1933-1943. , PID: 24831770
Udelson, J.E., Left ventricular shape: the forgotten stepchild of remodeling parameters (2017) JACC Heart Fail, 5, pp. 179-181. , PID: 28254123
Levelt, E., Mahmod, M., Piechnik, S.K., Ariga, R., Francis, J.M., Rodgers, C.T., Relationship between left ventricular structural and metabolic remodeling in type 2 diabetes (2016) Diabetes, 65, pp. 44-52. , COI: 1:CAS:528:DC%2BC28XjtF2iu7k%3D, PID: 26438611
Chong, C.R., Clarke, K., Levelt, E., Metabolic remodeling in diabetic cardiomyopathy (2017) Cardiovasc Res, 113, pp. 422-430
Walker, A.M., Patel, P.A., Rajwani, A., Groves, D., Denby, C., Kearney, L., Diabetes mellitus is associated with adverse structural and functional cardiac remodelling in chronic heart failure with reduced ejection fraction (2016) Diab Vasc Dis Res, 13, pp. 331-340. , COI: 1:CAS:528:DC%2BC2sXhtl2ntbzK, PID: 27334485
Germano, G., Kavanagh, P.B., Waechter, P., Areeda, J., Van Kriekinge, S., Sharir, T., A new algorithm for the quantitation of myocardial perfusion SPECT. I: Technical principles and reproducibility (2000) J Nucl Med, 41, pp. 712-719. , COI: 1:STN:280:DC%2BD3c3ivFSlsw%3D%3D, PID: 10768574
Abidov, A., Slomka, P.J., Nishina, H., Hayes, S.W., Kang, X., Yoda, S., Left ventricular shape index assessed by gated stress myocardial perfusion SPECT: Initial description of a new variable (2006) J Nucl Cardiol, 13, pp. 652-659. , PID: 16945745
Rosendorff, C., Black, H.R., Cannon, C.P., Gersh, B.J., Gore, J., Izzo, J.L., Jr., Treatment of hypertension in the prevention and management of ischemic heart disease: a scientific statement from the American Heart Association Council for High Blood Pressure Research and the Councils on Clinical Cardiology and Epidemiology and Prevention (2007) Circulation, 115, pp. 2761-2788. , PID: 17502569
Verberne, H.J., Acampa, W., Anagnostopoulos, C., Ballinger, J., Bengel, F., De Bondt, P., EANM procedural guidelines for radionuclide myocardial perfusion imaging with SPECT and SPECT, CT: 2015 revision (2015) Eur J Nucl Med Mol Imaging, 2015 (42), pp. 1929-1940
Petretta, M., Acampa, W., Evangelista, L., Daniele, S., Ferro, A., Cuocolo, A., Impact of inducible ischemia by stress SPECT (IDIS) investigators. Impact of inducible ischemia by stress SPECT in cardiac risk assessment in diabetic patients: Rationale and design of a prospective, multicenter trial (2008) J Nucl Cardiol, 15, pp. 100-104. , PID: 18242486
Acampa, W., Petretta, M., Evangelista, L., Daniele, S., Xhoxhi, E., De Rimini, M.L., Myocardial perfusion imaging and risk classification for coronary heart disease in diabetic patients. The IDIS study: A prospective, multicentre trial (2012) Eur J Nucl Med Mol Imaging, 39, pp. 387-395. , PID: 22109666
Akincioglu, C., Berman, D.S., Nishina, H., Kavanagh, P.B., Slomka, P.J., Abidov, A., Assessment of diastolic function using 16-frame 99mtc-sestamibi gated myocardial perfusion SPECT: Normal values (2005) J Nucl Med, 46, pp. 1102-1108. , PID: 16000278
Germano, G., Kiat, H., Kavanagh, P.B., Moriel, M., Mazzanti, M., Su, H.T., Automatic quantification of ejection fraction from gated myocardial perfusion SPECT (1995) J Nucl Med, 36, pp. 2138-2147. , COI: 1:STN:280:DyaK28%2FkvFWiuw%3D%3D, PID: 7472611
Germano, G., Berman, D.S., On the accuracy and reproducibility of quantitative gated myocardial perfusion SPECT (1999) J Nucl Med, 40, pp. 810-813. , COI: 1:STN:280:DyaK1M3ltFCksQ%3D%3D, PID: 10319755
Leuven, E., Sianesi, B., Stata Module to Perform Full Mahalanobis and Propensity Score Matching, Common Support Graphing, and Covariate Imbalance Testing, , http://ideas.repec.org/c/boc/bocode/s432001.html, version 4.0.11, Oct. 22, 2014. Statistical Software Components (SSC), Boston College Department of Economics
Austin, P.C., Balance diagnostics for comparing the distribution of baseline covariates between treatment groups in propensity-score matched samples (2009) Stat Med, 28, pp. 3083-3107. , PID: 19757444
DiPrete, T.A., Gangl, M., Assessing bias in the estimation of causal effects: Rosenbaum bounds on matching estimators and instrumental variables estimation with imperfect instruments (2004) Sociol Methodol, 34, pp. 271-310
Hölscher, M.E., Bode, C., Bugger, H., Diabetic cardiomyopathy: does the type of diabetes matter? (2016) Int J Mol Sci, 17, p. 2036
Lombardi, C., Spigoni, V., Gorga, E., Dei, C.A., Novel insight into the dangerous connection between diabetes and heart failure (2016) Herz., 41, pp. 201-207. , COI: 1:STN:280:DC%2BC28fptlOlsw%3D%3D, PID: 27071966
Boudina, S., Abel, E.D., Diabetic cardiomyopathy revisited (2007) Circulation, 115, pp. 3213-3223. , PID: 17592090
An, D., Rodrigues, B., Role of changes in cardiac metabolism in development of diabetic cardiomyopathy (2006) Am J Physiol Heart Circ Physiol, 291, pp. H1489-H1506. , COI: 1:CAS:528:DC%2BD28XhtFegtrjO, PID: 16751293
Nichols, G.A., Gullion, C.M., Koro, C.E., Ephross, S.A., Brown, J.B., The incidence of congestive heart failure in type 2 diabetes: an update (2004) Diab Care, 27, pp. 1879-1884
Douglas, P.S., Morrow, R., Ioli, A., Reichek, N., Left ventricular shape, afterload and survival in idiopathic dilated cardiomyopathy (1989) J Am Coll Cardiol, 13, pp. 311-315. , COI: 1:STN:280:DyaL1M7gvFyntA%3D%3D, PID: 2913109
Maffessanti, F., Caiani, E.G., Tamborini, G., Muratori, M., Sugeng, L., Weinert, L., Serial changes in left ventricular shape following early mitral valve repair (2010) Am J Cardiol, 106, pp. 836-842. , PID: 20816125
St John Sutton, M., Linde, C., Gold, M.R., Abraham, W.T., Ghio, S., Cerkvenik, J., Left ventricular architecture, long-term reverse remodeling, and clinical outcome in mild heart failure with cardiac resynchronization: results from the REVERSE trial (2017) JACC Heart Fail, 5, pp. 169-178. , PID: 28254122
Lorenzo-Almorós, A., Tuñón, J., Orejas, M., Cortés, M., Egido, J., Lorenzo, Ó., Diagnostic approaches for diabetic cardiomyopathy (2017) Cardiovasc Diabetol, 16, p. 28. , PID: 28231848
Assante, R., Acampa, W., Zampella, E., Arumugam, P., Nappi, C., Gaudieri, V., Coronary atherosclerotic burden vs. coronary vascular function in diabetic and nondiabetic patients with normal myocardial perfusion: A propensity score analysis (2017) Eur J Nucl Med Mol Imaging, 44 (7), pp. 1129-1135. , PID: 28293706
Ernande, L., Rietzschel, E.R., Bergerot, C., De Buyzere, M.L., Schnell, F., Groisne, L., Impaired myocardial radial function in asymptomatic patients with type 2 diabetes mellitus: A speckle-tracking imaging study (2010) J Am Soc Echocardiogr, 23, pp. 1266-1272. , PID: 20932716
Ernande, L., Bergerot, C., Girerd, N., Thibault, H., Davidsen, E.S., Gautier Pignon-Blanc, P., Longitudinal myocardial strain alteration is associated with left ventricular remodeling in asymptomatic patients with type 2 diabetes mellitus (2014) J Am Soc Echocardiogr, 27, pp. 479-488. , PID: 24508363
Gimelli, A., Liga, R., Clemente, A., Marras, G., Kusch, A., Marzullo, P., Left ventricular eccentricity index measured with SPECT myocardial perfusion imaging: An additional parameter of adverse cardiac remodeling (2017) J Nucl Cardiol
Medrano-Gracia, P., Cowan, B.R., Ambale-Venkatesh, B., Bluemke, D.A., Eng, J., Finn, J.P., (2014) J Cardiovasc Magn Reson, 16, p. 56. , PID: 25160814
Heagerty, A.M., Aalkjaer, C., Bund, S.J., Korsgaard, N., Mulvany, M.J., Small artery structure in hypertension: Dual process of remodeling and growth (1993) Hypertension, 21, pp. 391-397. , COI: 1:STN:280:DyaK3s3gvFKrsQ%3D%3D, PID: 8458640
Aquaro, G.D., Camastra, G., Monti, L., Lombardi, M., Pepe, A., Castelletti, S., Reference values of cardiac volumes, dimensions, and new functional parameters by MR: A multicenter, multivendor study (2017) J Magn Reson Imaging, 45, pp. 1055-1067. , PID: 27571232
Muraru, D., Badano, L.P., Peluso, D., Dal Bianco, L., Casablanca, S., Kocabay, G., Comprehensive analysis of left ventricular geometry and function by three-dimensional echocardiography in healthy adults (2013) J Am Soc Echocardiogr, 26, pp. 618-628. , PID: 23611056
J Nucl Cardiol (ISSN: 1071-3581, 1532-6551, 1532-6551electronic), 2017 Aug 14; 25(2): 394-403.
Export to BibTeX Export to EndNote
Paper type: Journal Article,
Impact factor: 4.011, 5-year impact factor: 3.456
Url: https://www.scopus.com/inward/record.uri?eid=2-s2.0-85028568975&doi=10.1007%2fs12350-017-1009-6&partnerID=40&md5=6a222d8d60e9f43cf6e5d83e98e647df
Keywords: Diabetes Mellitus, Cardiovascular Risk Factors, Gated Spect, Left Ventricular Shape Index, Adult, Article, Body Mass, Cardiac Gated Imaging, Cohort Analysis, Controlled Study, Coronary Artery Disease, Coronary Risk, Diabetic Patient, Female, Gated Single Photon Emission Computed Tomography, Heart Left Ventricle Ejection Fraction, Heart Left Ventricle Enddiastolic Volume, Heart Left Ventricle Endsystolic Volume, Heart Muscle Perfusion, Human, Hypercholesterolemia, Hypertension, Major Clinical Study, Middle Aged, Priority Journal, Propensity Score, Stress Radiography,
Affiliations:
*** IBB - CNR ***
Department of Advanced Biomedical Sciences, University Federico II, Via Pansini 5, 80131, Naples, Italy., Institute of Biostructure and Bioimaging, National Council of Research, Naples, Italy., Department of Translational Medical Sciences, University Federico II, Naples, Italy., Department of Medicine, Cedars-Sinai Medical Center, Los Angeles, CA, USA., David Geffen School of Medicine, UCLA, Los Angeles, CA, USA., Department of Advanced Biomedical Sciences, University Federico II, Via Pansini 5, 80131, Naples, Italy. cuocolo@unina.it.,
References:
Koitabashi, N., Kass, D.A., Reverse remodeling in heart failure-mechanisms and therapeutic opportunities (2011) Nat Rev Cardiol, 9, pp. 147-157. , PID: 2214307
Heusch, G., Libby, P., Gersh, B., Yellon, D., Böhm, M., Lopaschuk, G., Cardiovascular remodelling in coronary artery disease and heart failure (2014) Lancet, 383, pp. 1933-1943. , PID: 24831770
Udelson, J.E., Left ventricular shape: the forgotten stepchild of remodeling parameters (2017) JACC Heart Fail, 5, pp. 179-181. , PID: 28254123
Levelt, E., Mahmod, M., Piechnik, S.K., Ariga, R., Francis, J.M., Rodgers, C.T., Relationship between left ventricular structural and metabolic remodeling in type 2 diabetes (2016) Diabetes, 65, pp. 44-52. , COI: 1:CAS:528:DC%2BC28XjtF2iu7k%3D, PID: 26438611
Chong, C.R., Clarke, K., Levelt, E., Metabolic remodeling in diabetic cardiomyopathy (2017) Cardiovasc Res, 113, pp. 422-430
Walker, A.M., Patel, P.A., Rajwani, A., Groves, D., Denby, C., Kearney, L., Diabetes mellitus is associated with adverse structural and functional cardiac remodelling in chronic heart failure with reduced ejection fraction (2016) Diab Vasc Dis Res, 13, pp. 331-340. , COI: 1:CAS:528:DC%2BC2sXhtl2ntbzK, PID: 27334485
Germano, G., Kavanagh, P.B., Waechter, P., Areeda, J., Van Kriekinge, S., Sharir, T., A new algorithm for the quantitation of myocardial perfusion SPECT. I: Technical principles and reproducibility (2000) J Nucl Med, 41, pp. 712-719. , COI: 1:STN:280:DC%2BD3c3ivFSlsw%3D%3D, PID: 10768574
Abidov, A., Slomka, P.J., Nishina, H., Hayes, S.W., Kang, X., Yoda, S., Left ventricular shape index assessed by gated stress myocardial perfusion SPECT: Initial description of a new variable (2006) J Nucl Cardiol, 13, pp. 652-659. , PID: 16945745
Rosendorff, C., Black, H.R., Cannon, C.P., Gersh, B.J., Gore, J., Izzo, J.L., Jr., Treatment of hypertension in the prevention and management of ischemic heart disease: a scientific statement from the American Heart Association Council for High Blood Pressure Research and the Councils on Clinical Cardiology and Epidemiology and Prevention (2007) Circulation, 115, pp. 2761-2788. , PID: 17502569
Verberne, H.J., Acampa, W., Anagnostopoulos, C., Ballinger, J., Bengel, F., De Bondt, P., EANM procedural guidelines for radionuclide myocardial perfusion imaging with SPECT and SPECT, CT: 2015 revision (2015) Eur J Nucl Med Mol Imaging, 2015 (42), pp. 1929-1940
Petretta, M., Acampa, W., Evangelista, L., Daniele, S., Ferro, A., Cuocolo, A., Impact of inducible ischemia by stress SPECT (IDIS) investigators. Impact of inducible ischemia by stress SPECT in cardiac risk assessment in diabetic patients: Rationale and design of a prospective, multicenter trial (2008) J Nucl Cardiol, 15, pp. 100-104. , PID: 18242486
Acampa, W., Petretta, M., Evangelista, L., Daniele, S., Xhoxhi, E., De Rimini, M.L., Myocardial perfusion imaging and risk classification for coronary heart disease in diabetic patients. The IDIS study: A prospective, multicentre trial (2012) Eur J Nucl Med Mol Imaging, 39, pp. 387-395. , PID: 22109666
Akincioglu, C., Berman, D.S., Nishina, H., Kavanagh, P.B., Slomka, P.J., Abidov, A., Assessment of diastolic function using 16-frame 99mtc-sestamibi gated myocardial perfusion SPECT: Normal values (2005) J Nucl Med, 46, pp. 1102-1108. , PID: 16000278
Germano, G., Kiat, H., Kavanagh, P.B., Moriel, M., Mazzanti, M., Su, H.T., Automatic quantification of ejection fraction from gated myocardial perfusion SPECT (1995) J Nucl Med, 36, pp. 2138-2147. , COI: 1:STN:280:DyaK28%2FkvFWiuw%3D%3D, PID: 7472611
Germano, G., Berman, D.S., On the accuracy and reproducibility of quantitative gated myocardial perfusion SPECT (1999) J Nucl Med, 40, pp. 810-813. , COI: 1:STN:280:DyaK1M3ltFCksQ%3D%3D, PID: 10319755
Leuven, E., Sianesi, B., Stata Module to Perform Full Mahalanobis and Propensity Score Matching, Common Support Graphing, and Covariate Imbalance Testing, , http://ideas.repec.org/c/boc/bocode/s432001.html, version 4.0.11, Oct. 22, 2014. Statistical Software Components (SSC), Boston College Department of Economics
Austin, P.C., Balance diagnostics for comparing the distribution of baseline covariates between treatment groups in propensity-score matched samples (2009) Stat Med, 28, pp. 3083-3107. , PID: 19757444
DiPrete, T.A., Gangl, M., Assessing bias in the estimation of causal effects: Rosenbaum bounds on matching estimators and instrumental variables estimation with imperfect instruments (2004) Sociol Methodol, 34, pp. 271-310
Hölscher, M.E., Bode, C., Bugger, H., Diabetic cardiomyopathy: does the type of diabetes matter? (2016) Int J Mol Sci, 17, p. 2036
Lombardi, C., Spigoni, V., Gorga, E., Dei, C.A., Novel insight into the dangerous connection between diabetes and heart failure (2016) Herz., 41, pp. 201-207. , COI: 1:STN:280:DC%2BC28fptlOlsw%3D%3D, PID: 27071966
Boudina, S., Abel, E.D., Diabetic cardiomyopathy revisited (2007) Circulation, 115, pp. 3213-3223. , PID: 17592090
An, D., Rodrigues, B., Role of changes in cardiac metabolism in development of diabetic cardiomyopathy (2006) Am J Physiol Heart Circ Physiol, 291, pp. H1489-H1506. , COI: 1:CAS:528:DC%2BD28XhtFegtrjO, PID: 16751293
Nichols, G.A., Gullion, C.M., Koro, C.E., Ephross, S.A., Brown, J.B., The incidence of congestive heart failure in type 2 diabetes: an update (2004) Diab Care, 27, pp. 1879-1884
Douglas, P.S., Morrow, R., Ioli, A., Reichek, N., Left ventricular shape, afterload and survival in idiopathic dilated cardiomyopathy (1989) J Am Coll Cardiol, 13, pp. 311-315. , COI: 1:STN:280:DyaL1M7gvFyntA%3D%3D, PID: 2913109
Maffessanti, F., Caiani, E.G., Tamborini, G., Muratori, M., Sugeng, L., Weinert, L., Serial changes in left ventricular shape following early mitral valve repair (2010) Am J Cardiol, 106, pp. 836-842. , PID: 20816125
St John Sutton, M., Linde, C., Gold, M.R., Abraham, W.T., Ghio, S., Cerkvenik, J., Left ventricular architecture, long-term reverse remodeling, and clinical outcome in mild heart failure with cardiac resynchronization: results from the REVERSE trial (2017) JACC Heart Fail, 5, pp. 169-178. , PID: 28254122
Lorenzo-Almorós, A., Tuñón, J., Orejas, M., Cortés, M., Egido, J., Lorenzo, Ó., Diagnostic approaches for diabetic cardiomyopathy (2017) Cardiovasc Diabetol, 16, p. 28. , PID: 28231848
Assante, R., Acampa, W., Zampella, E., Arumugam, P., Nappi, C., Gaudieri, V., Coronary atherosclerotic burden vs. coronary vascular function in diabetic and nondiabetic patients with normal myocardial perfusion: A propensity score analysis (2017) Eur J Nucl Med Mol Imaging, 44 (7), pp. 1129-1135. , PID: 28293706
Ernande, L., Rietzschel, E.R., Bergerot, C., De Buyzere, M.L., Schnell, F., Groisne, L., Impaired myocardial radial function in asymptomatic patients with type 2 diabetes mellitus: A speckle-tracking imaging study (2010) J Am Soc Echocardiogr, 23, pp. 1266-1272. , PID: 20932716
Ernande, L., Bergerot, C., Girerd, N., Thibault, H., Davidsen, E.S., Gautier Pignon-Blanc, P., Longitudinal myocardial strain alteration is associated with left ventricular remodeling in asymptomatic patients with type 2 diabetes mellitus (2014) J Am Soc Echocardiogr, 27, pp. 479-488. , PID: 24508363
Gimelli, A., Liga, R., Clemente, A., Marras, G., Kusch, A., Marzullo, P., Left ventricular eccentricity index measured with SPECT myocardial perfusion imaging: An additional parameter of adverse cardiac remodeling (2017) J Nucl Cardiol
Medrano-Gracia, P., Cowan, B.R., Ambale-Venkatesh, B., Bluemke, D.A., Eng, J., Finn, J.P., (2014) J Cardiovasc Magn Reson, 16, p. 56. , PID: 25160814
Heagerty, A.M., Aalkjaer, C., Bund, S.J., Korsgaard, N., Mulvany, M.J., Small artery structure in hypertension: Dual process of remodeling and growth (1993) Hypertension, 21, pp. 391-397. , COI: 1:STN:280:DyaK3s3gvFKrsQ%3D%3D, PID: 8458640
Aquaro, G.D., Camastra, G., Monti, L., Lombardi, M., Pepe, A., Castelletti, S., Reference values of cardiac volumes, dimensions, and new functional parameters by MR: A multicenter, multivendor study (2017) J Magn Reson Imaging, 45, pp. 1055-1067. , PID: 27571232
Muraru, D., Badano, L.P., Peluso, D., Dal Bianco, L., Casablanca, S., Kocabay, G., Comprehensive analysis of left ventricular geometry and function by three-dimensional echocardiography in healthy adults (2013) J Am Soc Echocardiogr, 26, pp. 618-628. , PID: 23611056
Comparison of left ventricular shape by gated SPECT imaging in diabetic and nondiabetic patients with normal myocardial perfusion: A propensity score analysis
Background: Diabetes mellitus induces structural and functional cardiac alterations that can result in heart failure. Left ventricular (LV) shape is a dynamic component of cardiac geometry influencing its contractile function. However, few data are available comparing LV shape index in diabetic and nondiabetic patients without overt coronary artery disease after balancing for coronary risk factors. Methods: We studied 1168 patients with normal myocardial perfusion and normal LV ejection fraction on stress gated single-photon emission computed tomography (SPECT) imaging. To account for differences in baseline characteristics between diabetic and nondiabetic patients, we created a propensity score-matched cohort considering clinical variables, coronary risk factors, and stress type. Results: Before matching, diabetic patients were older, had higher prevalence of male gender and coronary risk factors, and higher end-diastolic and end-systolic LV shape index. After matching, all clinical characteristics were comparable between diabetic and nondiabetic patients, but diabetic patients still had higher end-diastolic and end-systolic LV shape index (both P < .001). At multivariable linear regression analysis, diabetes was a strong predictor of end-systolic LV shape index in the overall study population and in the propensity-matched cohort. Conclusions: Diabetic patients have higher values of LV shape index compared to nondiabetic patients also after balancing clinical characteristics by propensity score analysis. Shape indexes assessment by gated SPECT may be useful for identifying early LV remodeling in patients with diabetes. © 2017, American Society of Nuclear Cardiology.
Background: Diabetes mellitus induces structural and functional cardiac alterations that can result in heart failure. Left ventricular (LV) shape is a dynamic component of cardiac geometry influencing its contractile function. However, few data are available comparing LV shape index in diabetic and nondiabetic patients without overt coronary artery disease after balancing for coronary risk factors. Methods: We studied 1168 patients with normal myocardial perfusion and normal LV ejection fraction on stress gated single-photon emission computed tomography (SPECT) imaging. To account for differences in baseline characteristics between diabetic and nondiabetic patients, we created a propensity score-matched cohort considering clinical variables, coronary risk factors, and stress type. Results: Before matching, diabetic patients were older, had higher prevalence of male gender and coronary risk factors, and higher end-diastolic and end-systolic LV shape index. After matching, all clinical characteristics were comparable between diabetic and nondiabetic patients, but diabetic patients still had higher end-diastolic and end-systolic LV shape index (both P < .001). At multivariable linear regression analysis, diabetes was a strong predictor of end-systolic LV shape index in the overall study population and in the propensity-matched cohort. Conclusions: Diabetic patients have higher values of LV shape index compared to nondiabetic patients also after balancing clinical characteristics by propensity score analysis. Shape indexes assessment by gated SPECT may be useful for identifying early LV remodeling in patients with diabetes. © 2017, American Society of Nuclear Cardiology.
Comparison of left ventricular shape by gated SPECT imaging in diabetic and nondiabetic patients with normal myocardial perfusion: A propensity score analysis
| ▼ Animal Care, interventional procedures, anesthesia and analgesia of murine models in preclinical imaging |
| ▼ Comparison of noninvasive cardiac imaging modalities in patients with myocardial infarction |
Comparison of left ventricular shape by gated SPECT imaging in diabetic and nondiabetic patients with normal myocardial perfusion: A propensity score analysis
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Gaudieri V, Nappi C, Acampa W, Zampella E, Assante R, Mannarino T, Genova A, De Simini G, Klain M, Germano G, Petretta M, Cuocolo A
* Added prognostic value of left ventricular shape by gated SPECT imaging in patients with suspected coronary artery disease and normal myocardial perfusion (287 views)
J Nucl Cardiol (ISSN: 1071-3581, 1532-6551, 1532-6551electronic), 2017 Oct 25; N/D: N/D-N/D.
Impact Factor: 4.011
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Tumminia A, Milluzzo A, Cinti F, Parisi M, Tata F, Frasca F, Frittitta L, Vigneri R, Sciacca L
* Abnormal 1-hour post-load glycemia during pregnancy impairs post-partum metabolic status: a single-center experience (171 views)
J Endocrinol Invest (ISSN: 1720-8386, 0391-4097, 1720-8386electronic), 2017 Oct 24; N/D: N/D-N/D.
Impact Factor: 3.166
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Assante R, Acampa W, Zampella E, Arumugam P, Nappi C, Gaudieri V, Panico M, Magliulo M, Tonge CM, Petretta M, Cuocolo A
* Coronary atherosclerotic burden vs. coronary vascular function in diabetic and nondiabetic patients with normal myocardial perfusion: a propensity score analysis (348 views)
Eur J Nucl Med (ISSN: 1619-7070, 1619-7089, 1619-7070print), 2017 Mar 14; N/D: N/D-N/D.
Impact Factor: 7.704
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Monti SM, Supuran CT, De Simone G
* DPP-4 inhibitors: a patent review (2012 - 2014) (574 views)
Expert Opin Ther Pat (ISSN: 1354-3776, 1744-7674electronic), 2015 Feb; 25(2): 209-236.
Impact Factor: 4.626
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Tomasello MF, Sinopoli A, Pappalardo G
* On the Environmental Factors Affecting the Structural and Cytotoxic Properties of IAPP Peptides (443 views)
J Diabetes Res (ISSN: 2314-6745, 2314-6745print), 2015; articleID918573: 918573-918573.
Impact Factor: 2.431
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Coppo C, Bonfanti D, Bo S, Giordanino C, Gallo M, Cococcia S, Ciccone G, Smedile A, Ciancio A, Bugianesi E, Fagoonee S, Pellicano R, Rizzetto M, Saracco GM
* Risk of microangiopathy in type 2 diabetes mellitus patients with or without chronic hepatitis C: Results of a retrospective long-term controlled cohort study (303 views)
Dig Liver Dis (ISSN: 1590-8658, 1590-8658linking), 2015; 47(5): 405-410.
Impact Factor: 2.719
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Le Moli R, Muscia V, Tumminia A, Frittitta L, Buscema M, Palermo F, Sciacca L, Squatrito S, Vigneri R
* Type 2 diabetic patients with Graves' disease have more frequent and severe Graves' orbitopathy (896 views)
Nutrition (ISSN: 0939-4753, 1590-3729electronic), 2015; 25(5): 452-457.
Impact Factor: 3.39
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Petretta M, Acampa W, Cuocolo A
* Cardiovascular risk stratification in diabetic patients: is all in METS? (474 views)
J Nucl Cardiol (ISSN: 1071-3581, 1532-6551, 1532-6551electronic), 2014 Dec; 21(6): 1144-1147.
Impact Factor: 2.942
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Acampa W, Cantoni V, Green R, Maio F, Daniele S, Nappi C, Gaudieri V, Punzo G, Petretta M, Cuocolo A
* Prognostic value of normal stress myocardial perfusion imaging in diabetic patients: a meta-analysis (459 views)
J Nucl Cardiol (ISSN: 1071-3581, 1071-3581linking, 1532-6551), 2014 Oct; 21(5): 893-902.
Impact Factor: 2.942
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Acampa W, Petretta M, Cuocolo R, Daniele S, Cantoni V, Cuocolo A
* Warranty period of normal stress myocardial perfusion imaging in diabetic patients: A propensity score analysis (414 views)
J Nucl Cardiol (ISSN: 1071-3581, 1532-6551, 1532-6551electronic), 2014 Feb; 21(1): 50-56.
Impact Factor: 2.942
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Petretta M, Acampa W, Evangelista L, Daniele S, Zampella E, Assante R, Nappi C, Cantoni V, Fiumara G, Cuocolo A
* Reclassification of cardiovascular risk by myocardial perfusion imaging in diabetic patients with abnormal resting electrocardiogram (492 views)
Nutrition (ISSN: 0939-4753, 1590-3729electronic), 2014; 24(6): 588-593.
Impact Factor: 3.323
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Milardi D, Sciacca MF, Randazzo L, Raudino A, La Rosa C
* The role of calcium, lipid membranes and islet amyloid polypeptide in the onset of type 2 diabetes: Innocent bystanders or partners in a crime? (586 views)
Front Endocrinol (ISSN: 1664-2392, 1664-2392linking, 1664-2392print), 2014; 5(DEC): 216-216.
Impact Factor: 3.675
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Bellia F, GrassoG
* The role of copper(II) and zinc(II) in the degradation of human and murine IAPP by insulin-degrading enzyme (579 views)
J Mass Spectrom (ISSN: 1076-5174, 1096-9888), 2014; 49(4): 274-279.
Impact Factor: 2.379
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Ferro A, Petretta M, Acampa W, Fiumara G, Daniele S, Petretta MP, Cantoni V, Cuocolo A
* Post-stress left ventricular ejection fraction drop in patients with diabetes: A gated myocardial perfusion imaging study (436 views)
Bmc Cardiovasc Disor (ISSN: 1471-2261), 2013 Nov 14; 13: 99-99.
Impact Factor: 1.5
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Petretta M, Acampa W, Daniele S, Petretta MP, Plaitano M, Cuocolo A
* Transient ischemic dilation in patients with diabetes mellitus: prognostic value and effect on clinical outcome after coronary revascularization (346 views)
Circ Cardiovasc Imaging (ISSN: 1942-0080, 1941-9651), 2013 Nov; 6(6): 908-915.
Impact Factor: 1.783
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Petretta M, Fiumara G, Petretta MP, Cuocolo A
* Detection of silent myocardial ischemia: is it clinically relevant? (285 views)
J Nucl Cardiol (ISSN: 1532-6551, 1071-3581, 1532-6551electronic), 2013 Oct; 20(5): 707-710.
Impact Factor: 2.645
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Paolillo S, Rengo G, Pagano G, Pellegrino T, Savarese G, Femminella GD, Tuccillo M, Boemio A, Attena E, Formisano R, Petraglia L, Scopacasa F, Galasso G, Leosco D, Trimarco B, Cuocolo A, Perrone-Filardi P
* Impact of diabetes on cardiac sympathetic innervation in patients with heart failure: a 123I meta-iodobenzylguanidine (123I MIBG) scintigraphic study (314 views)
Diabetes Care (ISSN: 1935-5548, 0149-5992), 2013 Sep; 36(8): 2395-2401.
Impact Factor: 8.57
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Vitale M, Luongo D, Naviglio D, Bozzetto L, Mirabella M, Rivieccio AM, Giacco A, Rivellese AA
* Trans fatty acids consumption in type 1 diabetic patients: evaluation by dietary records and measurement in serum phospholipids (390 views)
Acta Diabetol (ISSN: 0940-5429, 1432-5233electronic), 2013 Aug; 50(4): 651-654.
Impact Factor: 3.679
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Mancini M, Masulli M, Liuzzi R, Mainenti PP, Ragucci M, Maurea S, Riccardi G, Vaccaro O
* Renal duplex sonographic evaluation of type 2 diabetic patients (453 views)
J Ultrasound Med (ISSN: 1550-9613, 0278-4297), 2013 Jun; 32(6): 1033-1040.
Impact Factor: 1.532
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Acampa W, Petretta M, Daniele S, Del Prete G, Assante R, Zampella E, Cuocolo A
* Incremental prognostic value of stress myocardial perfusion imaging in asymptomatic diabetic patients (453 views)
Atherosclerosis (ISSN: 0021-9150, 1879-1484), 2013 Apr; 227(2): 307-312.
Impact Factor: 3.971
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Paolillo S, Rengo G, Pagano G, Pellegrino T, Savarese G, Femminella GD, Tuccillo M, Boemio A, Attena E, Formisano R, Petraglia L, Scopacasa F, Galasso G, Leosco D, Trimarco B, Cuocolo A, Perrone-Filardi P
* IMPACT OF DIABETES MELLITUS IN IODINE-123 META-IODOBENZYLGUANIDINE (I123MIBG) CARDIAC UPTAKE IN PATIENTS WITH HEART FAILURE (263 views)
Journal Of The American College Of Cardiology (ISSN: 0735-1097), 2013 Mar 12; 61(10): 2395-2401.
Impact Factor: 15.343
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Petretta M, Acampa W, Daniele S, Petretta MP, Nappi C, Assante R, Zampella E, Costanzo P, Perrone-Filardi P, Cuocolo A
* Transient ischemic dilation in SPECT myocardial perfusion imaging for prediction of severe coronary artery disease in diabetic patients (703 views)
J Nucl Cardiol (ISSN: 1071-3581, 1532-6551, 1532-6551electronic), 2013 Feb; 20(1): 45-52.
Impact Factor: 2.645
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Petretta M, Acampa W, Fiumara G, Cuocolo A
* Cardiovascular risk stratification in diabetic patients (396 views)
Clin Transl Imaging (ISSN: 2281-5872, 2281-5872print, 2281-7565online), 2013; 1(5): 325-339.
Impact Factor: 0
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Bellia F, Pietropaolo A, Grasso G
* Formation of insulin fragments by insulin-degrading enzyme: The role of zinc(II) and cystine bridges (461 views)
J Mass Spectrom (ISSN: 1076-5174, 1096-9888), 2013; 48(2): 135-140.
Impact Factor: 2.709
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Giallauria F, Acampa W, Ricci F, Gallicchio R, Xhoxhi E, Vitelli A, D'Agostino M, Lucci R, Vigorito C, Cuocolo A
* Effects of exercise training started within 2 weeks after acute myocardial infarction on myocardial perfusion and left ventricular function: A gated SPECT imaging study (442 views)
Eur J Prev Cardiol (ISSN: 2047-4873, 2047-4881), 2012 Dec; 19(6): 1410-1419.
Impact Factor: 2.675
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Grasso G, Salomone F, Tundo GR, Pappalardo G, Ciaccio C, Spoto G, Pietropaolo A, Coletta M, Rizzarelli E
* Metal ions affect insulin-degrading enzyme activity (495 views)
J Chem Res (ISSN: 1873-3344, 0162-0134, 0162-0134print), 2012 Dec; 117: 351-358.
Impact Factor: 3.197
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Assante R, Petretta M, Acampa W, Daniele S, Nappi C, Zampella E, Perrone-Filardi P, Cuocolo A
* Prediction of Severe Coronary Artery Disease in Diabetic Patients with Gated SPECT Myocardial Perfusion Imaging (241 views)
Eur J Nucl Med (ISSN: 1619-7070, 1619-7089, 0340-6997), 2012 Oct; 39: N/D-N/D.
Impact Factor: 5.114
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Stanzione F, De Simone A, Esposito L, Vitagliano L
* Dynamical Properties of Steric Zipper Polymorphs Formed by a IAPP-Derived Peptide (462 views)
Protein Pept Lett (ISSN: 0929-8665, 1875-5305), 2012 Sep; 19(8): 846-851.
Impact Factor: 1.994
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Marciano C, Galderisi M, Gargiulo P, Acampa W, D'Amore C, Esposito R, Capasso E, Savarese G, Casaretti L, Lo Iudice F, Esposito G, Rengo G, Leosco D, Cuocolo A, Perrone-Filardi P
* Effects of type 2 diabetes mellitus on coronary microvascular function and myocardial perfusion in patients without obstructive coronary artery disease (932 views)
Eur J Nucl Med (ISSN: 1619-7070, 1619-7089, 0340-6997), 2012 Jul; 39(7): 1199-1206.
Impact Factor: 5.114
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Bozzetto L, Prinster A, Annuzzi G, Costagliola L, Mangione A, Vitelli A, Mazzarella R, Longobardo M, Mancini M, Vigorito C, Riccardi G, Rivellese AA
* Liver fat is reduced by an isoenergetic MUFA diet in a controlled randomized study in type 2 diabetic patients (940 views)
Diabetes Care (ISSN: 1935-5548, 0149-5992, 1935-5548electronic), 2012 Jul; 35(7): 1429-1435.
Impact Factor: 7.735
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Perrone-Filardi P, Musella F, Savarese G, Cecere M, Marciano C, Scala O, Rengo G, Dellegrottaglie S, Cuocolo A, Leosco D
* Coronary computed tomography: current role and future perspectives for cardiovascular risk stratification (482 views)
Eur Heart J-Card Img (ISSN: 2047-2412, 2047-2404, 2047-2412electronic), 2012 Jun; 13(6): 453-458.
Impact Factor: 3.669
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Franchin A, Corradin ML, Giantin V, Rossi F, Zanatta F, Attanasio F, Toffanello ED, Manzato E
* Diabetes in a geriatric ward: Efficacy and safety of new insulin analogs in very old inpatients (292 views)
Aging Clin Exp Res (ISSN: 1594-0667, 1720-8319), 2012 Jun; 24(SUPPL.3): 17-19.
Impact Factor: 1.006
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Acampa W, Petretta M, Evangelista L, Daniele S, Xhoxhi E, De Rimini ML, Cittanti C, Marranzano F, Spadafora M, Baldari S, Mansi L, Cuocolo A
* Myocardial perfusion imaging and risk classification for coronary heart disease in diabetic patients. The IDIS study: A prospective, multicentre trial (477 views)
Eur J Nucl Med (ISSN: 1619-7070, 1619-7089, 0340-6997), 2012 Mar; 39(3): 387-395.
Impact Factor: 5.114
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Berti V, Sciagrà R, Acampa W, Ricci F, Cerisano G, Gallicchio R, Vigorito C, Pupi A, Cuocolo A
* Relationship between infarct size and severity measured by gated SPECT and long-term left ventricular remodelling after acute myocardial infarction (548 views)
Eur J Nucl Med (ISSN: 1619-7070, 1619-7089, 0340-6997), 2011 Jun; 38(6): 1124-1131.
Impact Factor: 4.991
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Acampa W, Di Taranto MD, Morgante A, Salvatore B, Evangelista L, Ricci F, Costanzo P, De Sisto E, Filardi PP, Petretta M, Fortunato G, Cuocolo A
* C-reactive protein levels are associated with paraoxonase polymorphism L55M in patients undergoing cardiac SPECT imaging (387 views)
Scand J Clin Lab Invest (ISSN: 0036-5513, 1502-7686), 2011 May; 71(3): 179-184.
Impact Factor: 1.156
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Scognamiglio PL, Doti N, Grieco P, Pedone C, Ruvo M, Marasco D
* Discovery Of Small Peptide Antagonists Of Ped/Pea15-D4alpha Interaction From Simplified Combinatorial Libraries (504 views)
Chem Biol Drug Des (ISSN: 1747-0277, 1747-0285), 2011 May; 77(5): 319-327.
Impact Factor: 2.282
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Striano P, Caranci F, Pappata S, Zara F, Striano S
* Hemidystonia in uncontrolled type 2 diabetes mellitus (291 views)
Arch Neurol (ISSN: 1538-3687electronic, 0003-9942linking), 2011 May; 68(5): 674-675.
Impact Factor: 7.584
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Berti V, Ricci F, Gallicchio R, Acampa W, Cerisano G, Vigorito C, Sciagra'R, Pupi A, Cuocolo A
* Infarct Size And Severity Measured By Gated Spect For Predicting The Long-Term Left Ventricular Remodelling After Acute Myocardial Infarction (241 views)
European Heart Journal Supplements, 2011 Apr; 4: N/D-N/D.
Impact Factor: 14.723
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Bozzetto L, Prinster A, Mancini M, Giacco R, De Natale C, Salvatore M, Riccardi G, Rivellese AA, Annuzzi G
* Liver fat in obesity: role of type 2 diabetes mellitus and adipose tissue distribution (461 views)
Eur J Clin Invest (ISSN: 0014-2972, 1365-2362, 0014-2972linking), 2011 Jan; 41(1): 39-44.
Impact Factor: 3.018
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Milardi D, Sciacca MFM, Pappalardo M, Grasso DM, La Rosa C
* The Role Of Aromatic Side-Chains In Amyloid Growth And Membrane Interaction Of The Islet Amyloid Polypeptide Fragment Lanflvh (458 views)
Eur Biophys J, 2011 Jan; 40(1): 1-12.
Impact Factor: 3.832
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Spadafora M, Varrella P, Acampa W, Spirito M, Nappi C, Mansi L, Miletto P, Rosato G, Cuocolo A
* Direct imaging of viable myocardium by gated SPECT in patients with ischaemic left ventricular dysfunction (417 views)
Eur J Nucl Med (ISSN: 1619-7070, 1619-7089, 0340-6997), 2010 Sep; 37(9): 1730-1735.
Impact Factor: 5.036
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Bombardieri E, Ambrosini V, Aktolun C, Baum RP, Bishof-delaloye A, Del Vecchio S, Maffioli L, Mortelmans L, Oyen W, Pepe G, Chiti A
* In-111-pentetreotide scintigraphy: procedure guidelines for tumour imaging (479 views)
Eur J Nucl Med (ISSN: 1619-7070, 1619-7089, 0340-6997), 2010 Jul; 37(7): 1441-1448.
Impact Factor: 5.036
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Cuocolo A, Petretta M, Acampa W, De Falco T
* Gated SPECT myocardial perfusion imaging: The further improvements of an excellent tool (376 views)
Q J Nucl Med Mol Im (ISSN: 1824-4785, 1824-4478, 1824-4785linking), 2010 Apr; 54(2): 129-144.
Impact Factor: 1.724
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Giacco R, Clemente G, Cipriano D, Luongo D, Viscovo D, Patti L, Di Marino L, Giacco A, Naviglio D, Bianchi MA, Ciati R, Brighenti F, Rivellese AA, Riccardi G
* Effects of the regular consumption of wholemeal wheat foods on cardiovascular risk factors in healthy people (950 views)
Nutrition (ISSN: 0939-4753, 1590-3729electronic), 2010 Mar; 20(3): 186-194.
Impact Factor: 3.438
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Acampa W, Caprio MG, Nicolai E, Liuzzi R, Capasso E, Luongo L, Petretta M, Cuocolo A
* Assessment of poststress left ventricular ejection fraction by gated SPECT: Comparison with equilibrium radionuclide angiocardiography (475 views)
Eur J Nucl Med (ISSN: 1619-7070, 1619-7089, 0340-6997), 2010 Feb; 37(2): 349-356.
Impact Factor: 5.036
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Capaccio D, Ciccodicola A, Sabatino L, Casamassimi A, Pancione M, Fucci A, Febbraro, Merlino A, Graziano G, Colantuoni V
* A novel germline mutation in Peroxisome Proliferator-Activated Receptor γ gene associated with large intestine polyp formation and dyslipidemia (431 views)
Bba-Gen Subjects (ISSN: 0925-4439, 0006-3002, 1570-9639), 2010; 1802(6): 572-581.
Impact Factor: 2.773
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Cuocolo A, Concilio C, Acampa W, Ferro A, Evangelista L, Daniele S, Petretta M
* Cardiovascular risk stratification of diabetic patients (591 views)
Minerva Endocrinol (ISSN: 0391-1977, 1827-1634electronic, 0391-1977linking), 2009 Sep; 34(3): 205-221.
Impact Factor: 1.464
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Palladino P, Ronga L, Benedetti E, Rossi F, Ragone R
* Peptide Fragment Approach to Prion Misfolding: The Alpha-2 Domain (402 views)
Int J Pept Res Ther (ISSN: 1573-3149, 0929-5666), 2009 Sep; 15(3): 165-176.
Impact Factor: 0.869
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Masulli M, Mancini M, Liuzzi R, Daniele S, Mainenti PP, Vergara E, Genovese S, Salvatore M, Vaccaro O
* Measurement of the intrarenal arterial resistance index for the identification and prediction of diabetic nephropathy (700 views)
Nutrition (ISSN: 0939-4753, 1590-3729electronic, 0939-4753linking), 2009 Jun; 19(5): 358-364.
Impact Factor: 3.517
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Sandomenico A, Monti SM, Sabatella M, De Capua A, Tornatore L, Doti N, Viparelli F, Dathan NA, Pedone C, Ruvo M, Marasco D
* Protein-protein interactions: a simple strategy to identify binding sites and peptide antagonists (607 views)
Chem Biol Drug Des (ISSN: 1747-0285, 1747-0277), 2009 May; 73(5): 483-493.
Impact Factor: 2.473
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De Simone G, Supuran CT
* Drug Design of Antiobesity Carbonic Anhydrase Inhibitors (336 views)
Drug Des Of Zinc Enzyme Inhibitors (ISSN: 9780-4702, 9780-470275009), 2009; 66(DECEMBERSPEC.I): 241-254.
Impact Factor: 1.156
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Milardi D, Pappalardo M, Pannuzzo M, Grasso DM, Rosa CL
* The role of the Cys2-Cys7 disulfide bridge in the early steps of Islet amyloid polypeptide aggregation: A molecular dynamics study (447 views)
Chem Phys Lett (ISSN: 0009-2614), 2008 Oct 1; 463(4-6): 396-399.
Impact Factor: 2.169
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Ferro A, Costanzo P, Acampa W, Daniele S, Evangelista L, De Marino M, Ricci F, Vassallo S, Petretta M, Cuocolo A
* The IDIS Investigators: Combined Evaluation of Myocardial Perfusion and Left Ventricular Function by Gated SPECT Predicts Severe Coronary Artery Disease in Diabetic Patients (253 views)
Eur J Nucl Med (ISSN: 1619-7070, 1619-7089, 0340-6997), 2008 Oct; 35: N/D-N/D.
Impact Factor: 4.532
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Sciacca MFM, Pappalardo M, Milardi D, Grasso DM, La Rosa C
* Calcium-Activated Membrane Interaction Of The Islet Amyloid Polypeptide: Implications In The Pathogenesis Of Type Ii Diabetes Mellitus (1045 views)
Arch Biochem Biophys, 2008 Sep 15; 65(1-2): 291-298.
Impact Factor: 3.043
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Viparelli F, Cassese A, Doti N, Paturzo F, Marasco D, Dathan NA, Monti SM, Basile G, Ungaro P, Sabatella M, Miele C, Teperino R, Consiglio E, Pedone C, Beguinot F, Formisano P, Ruvo M
* Targeting of PED/PEA-15 molecular interaction with phospholipase D1 enhances insulin sensitivity in skeletal muscle cells (437 views)
Jbc Papers (ISSN: 0021-9258, 1083-351x, 0021-9258linking), 2008 Sep 1; 283(31): 21769-21778.
Impact Factor: 5.52
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Acampa W, Petretta M, Evangelista L, Nappi G, Luongo L, Petretta MP, Cuocolo A
* Stress cardiac single-photon emission computed tomographic imaging late after coronary artery bypass surgery for risk stratification and estimation of time to cardiac events (325 views)
J Thorac Cardiovasc Surg (ISSN: 0022-5223, 1097-685x), 2008 Jul; 136(1): 46-51.
Impact Factor: 3.037
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Petretta M, Soricelli A, Storto G, Cuocolo A
* Assessment of coronary flow reserve using single photon emission computed tomography with technetium 99m-labeled tracers (587 views)
J Nucl Cardiol (ISSN: 1532-6551, 1071-3581, 1532-6551electronic), 2008 May; 15(3): 456-465.
Impact Factor: 2.442
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Goldfine ID, Maddux BA, Youngren JF, Reaven G, Accili D, Trischitta V, Vigneri R, Frittitta L
* The role of membrane glycoprotein plasma cell antigen 1 ectonucleotide pyrophosphatase phosphodiesterase 1 in the pathogenesis of insulin resistance and related abnormalities (1197 views)
Endocrine Reviews (ISSN: 0163-769x), 2008 Feb; 29(1): 62-75.
Impact Factor: 18.562
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Petretta M, Acampa W, Evangelista L, Daniele S, Ferro A, Cuocolo A
* Impact of inducible ischemia by stress SPECT in cardiac risk assessment in diabetic patients: Rationale and design of a prospective, multicenter trial (310 views)
J Nucl Cardiol (ISSN: 1071-3581, 1532-6551, 1532-6551electronic), 2008 Jan; 15(1): 100-104.
Impact Factor: 2.442
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Sorrentino AR, Acampa W, Petretta M, Mainolfi C, Salvatore M, Cuocolo A
* Comparison of the prognostic value of SPECT after nitrate administration and metabolic imaging by PET in patients with ischaemic left ventricular dysfunction (337 views)
Eur J Nucl Med (ISSN: 1619-7070, 1619-7089, 0340-6997), 2007 Apr; 34(4): 558-562.
Impact Factor: 4.101
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Storto G, Pellegrino T, Sorrentino AR, Luongo L, Petretta M, Cuocolo A
* Estimation of coronary flow reserve by sestamibi imaging in type 2 diabetic patients with normal coronary arteries (398 views)
J Nucl Cardiol (ISSN: 1532-6551, 1071-3581, 1532-6551electronic), 2007 Apr; 14(2): 194-199.
Impact Factor: 2.359
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Evangelista L, Ferro A, Acampa W, Capasso R, De Rimini ML, Cittanti C, Marranzano F, Spadafora M, Baldari S, Mansi L, Petretta M, Cuocolo A
* A prospective, multi-center trial to assess the prevalence and the clinical predictors of myocardial ischemia in patients presenting with diabetes mellitus and suspected or documented coronary artery disease (237 views)
Eur J Nucl Med (ISSN: 1619-7070, 1619-7089, 0340-6997), 2006 Sep; 33: N/D-N/D.
Impact Factor: 4.041
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Di Bonito P, Rinaldi M, Genovese S, Parillo M, Gruppo di studio regionale FADOI, Lucibelli L, Miano P, Piantadosi S, Sassi G, Caiazzo G, Marrone G, De Feo EM, Piscopo G, Di Domenico A, Visconti M, Nicoletti A, Luca S, Cunzolo D, Cianciullo M, Tortora A, Zinno A, D’Auria S, Rinaldi C, Pascucci D, Gennaro MD, Zerella F, Forte R, Grimaldi U, Foschi A, Boniello B, Garrulo A, Pontieri A, Dello Iacono N, Mancini M, D’avanzo A, Di Guglielmo G, Sossio F
* Known And Unknown Diabetes Mellitus Among Patients Hositalized In Internal Medicine Units Of The Campania Region (southern Italy) (237 views)
G It Diabetol Metab, 2006; 26: 5-9.
Impact Factor: 0
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Colao A, Di Somma C, Cuocolo A, Spinelli L, Acampa W, Spiezia S, Rota F, Savanelli MC, Lombardi G
* Does a gender-related effect of growth hormone (GH) replacement exist on cardiovascular risk factors, cardiac morphology, and performance and atherosclerosis? Results of a two-year open, prospective study in young adult men and women with severe GH deficiency (450 views)
J Clin Endocrinol Metab (ISSN: 0021-972x), 2005 Sep; 90(9): 5146-5155.
Impact Factor: 6.02
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Vicario MLE, Cirillo L, Storto G, Pellegrino T, Ragone N, Fontanella L, Petretta M, Bonaduce D, Cuocolo A
* Influence of risk factors on coronary flow reserve in patients with 1-vessel coronary artery disease (365 views)
J Nucl Med (ISSN: 0161-5505, 1535-5667, 1535-5667electronic), 2005 Sep; 46(9): 1438-1443.
Impact Factor: 4.684
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Foti D, Chiefari E, Fedele M, Iuliano R, Brunetti L, Paonessa F, Manfioletti G, Barbetti F, Brunetti A, Croce CM, Fusco A, Brunetti A
* Lack of the architectural factor HMGA1 causes insulin resistance and diabetes in humans and mice (391 views)
Nat Med (ISSN: 1078-8956, 0034-7264), 2005 Jul; 11(7): 765-773.
Impact Factor: 28.878
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Petretta M, Storto G, Acampa W, Sansone V, Evangelista L, Spinelli L, Cuocolo A
* Relation between wall thickening on gated perfusion SPECT and functional recovery after coronary revascularization in patients with previous myocardial infarction (372 views)
Eur J Nucl Med (ISSN: 1619-7070, 1619-7089, 0340-6997), 2004 Dec; 31(12): 1599-1605.
Impact Factor: 3.935
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Clemente G, Mancini M, Nazzaro F, Lasorella G, Rivieccio A, Palumbo AM, Rivellese AA, Ferrara L, Giacco R
* Effects of different dairy products on postprandial lipemia (1088 views)
Nutrition (ISSN: 0939-4753, 1590-3729electronic), 2003 Dec; 13(6): 377-383.
Impact Factor: 2.148
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Spinelli L, Petretta M, Acampa W, He W, Petretta A, Bonaduce D, Cuocolo A
* Prognostic value of combined assessment of regional left ventricular function and myocardial perfusion by dobutamine and rest gated SPECT in patients with uncomplicated acute myocardial infarction (429 views)
J Nucl Med (ISSN: 0161-5505, 1535-5667, 1535-5667electronic), 2003 Jul; 44(7): 1023-1029.
Impact Factor: 4.899
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Pauciullo P, Giannino A, De Michele M, Gentile M, Liguori R, Argiriou A, Carlotto A, Faccenda F, Mancini M, Bond MG, De Simone V, Rubba P
* Increased carotid artery intima-media thickness is associated with a novel mutation of low-density lipoprotein receptor independently of major cardiovascular risk factors (735 views)
Metab Clin Exp (ISSN: 0026-0495, 1532-8600), 2003; 52(11): 1433-1438.
Impact Factor: 2.013
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Colao A, Di Somma C, Cuocolo A, Spinelli L, Tedesco N, Pivonello R, Bonaduce D, Salvatore M, Lombardi G
* Improved cardiovascular risk factors and cardiac performance after 12 months of growth hormone (GH) replacement in young adult patients, with GH deficiency (634 views)
J Clin Endocrinol Metab (ISSN: 0021-972x), 2001 May; 86(5): 1874-1881.
Impact Factor: 5.16
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Tedeschi E, Marano I, Savarese F, Olibet G, Di Salvo E, Brunetti A, Sodano A
Neurological deficit following spinal anaesthesia: MRI and CT evidence of spinal cord gas embolism (371 views)
Neuroradiology (ISSN: 0028-3940, 1432-1920electronic, 0028-3940linking), 1999 Apr; 41(4): 275-278.
Impact Factor: 1.287
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Giacco R, Mancini M, Clemente G, Coppola S, Lasorella G, D’Avanzo G, Rivieccio A M, Ruffa G, Brighenti F, Rivellese AA, Riccardi G
Metabolic effects of resistant starch in patients with Type 2 diabetes (527 views)
Diabetes Nutr Metab Clin Exp (ISSN: 0394-3402), 1998; 11(6): 330-335.
Impact Factor: 0.629
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Ferrara LA, Iannuzzi R, Gaeta I, Mancini M, Guida L, Marotta T
Left ventricular hypertrophy and hypertension (369 views)
Clin Exp Hypertens Informa Healthcare, 1996 Jul; 15(6): 1025-1032.
Impact Factor: 0
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Ferrara LA, Mancini M, Celentano A, Galderisi M, Iannuzzi R, Marotta T, Gaeta I
Early changes of the arterial carotid wall in uncomplicated primary hypertensive patients: Study by ultrasound high-resolution B-mode imaging (284 views)
Arterioscler Thromb Vasc Biol Arteriosclerosis Thrombosis And Vascular Biology (ISSN: 1079-5642, 1049-8834), 1994 Sep; 14(8): 1290-1296.
Impact Factor: 5.317
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Manna R, Salvatore M, Di Leo MA, Scuderi F, Greco AV, Ghirlanda G, Gambassi G
Relationship between urinary neopterin excretion and islet cell antibodies in type 1 (insulin-dependent) diabetes (432 views)
Diabetes Res (ISSN: 0265-5985), 1991 May; 17(1): 33-36.
Impact Factor: 0
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Benzi L, Trischitta V, Ciccarone A, Cecchetti P, Brunetti A, Squatrito S, Marchetti P, Vigneri R, Navalesi R
Improvement with metformin in insulin internalization and processing in monocytes from NIDDM patients (254 views)
Diabetesdiabetes (ISSN: 0012-1797), 1990 Jul; 39(7): 844-849.
Impact Factor: 8.675
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Ferrara LA, Iannuzzi R, Mancini M, Iannuzzi A, Celentano A, Galderisi M
Peripheral Arterial Haemodinamics In Primary Hypertension: Influences Of Other Cardiovascular Risk Factors (303 views)
American Journal Of Hypertension 3, 1990; N/D: 110A-110A.
Impact Factor: 0
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Trischitta V, Brunetti A, Chiavetta A, Benzi L, Papa V, Vigneri R
Defects in insulin-receptor internalization and processing in monocytes of obese subjects and obese NIDDM patients (314 views)
Diabetesdiabetes (ISSN: 0012-1797), 1989 Dec; 38(12): 1579-1584.
Impact Factor: 8.675
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Manna R, Salvatore M, Scuderi F, Papa G, Marietti G, Greco AV, Ghirlanda G, Gambassi G
Negative correlation between ICA persistence and beta cell restoration after IDDM diagnosis (318 views)
Diabetes Res (ISSN: 0265-5985), 1988 Nov; 9(3): 101-103.
Impact Factor: 0
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Trischitta V, Benzi L, Brunetti A, Cecchetti P, Marchetti P, Vigneri R, Navalesi R
Intracellular insulin processing is altered in monocytes from patients with type II diabetes mellitus (971 views)
J Clin Endocrinol Metab (ISSN: 0021-972x), 1987 May; 64(5): 914-920.
Impact Factor: 4.575
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* Effectiveness on major cardiovascular risk factors of an educational program to promote a Mediterranean type of diet among the employees of the company FCA Italia S. p (0 views)
Diabetes Res Clin Pract (ISSN: 0168-8227linking), 2021 Sep; 179: 109009-109009.
Impact Factor:
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Ciancio A, Ribaldone DG, Dotta A, Giordanino C, Sacco M, Fagoonee S, Pellicano R, Saracco GM
* Long-term follow-up of diabetic and non-diabetic patients with chronic hepatitis C successfully treated with direct-acting antiviral agents (51 views)
Liver Int (ISSN: 1478-3223linking), 2021 Feb; 41(2): 276-287.
Impact Factor: 5.175
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Megna R, Zampella E, Assante R, Nappi C, Gaudieri V, Mannarino T, Cantoni V, Green R, Daniele S, Mainolfi CG, Acampa W, Petretta M, Cuocolo A
* Temporal trends of abnormal myocardial perfusion imaging in a cohort of Italian subjects: Relation with cardiovascular risk factors (311 views)
J Nucl Cardiol (ISSN: 1071-3581linking, 1532-6551electronic), 2020 Dec; 27(6): 2167-2177.
Impact Factor: 3.847
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Clemente G, Giorgini M, Mancini M, Gallo M, Amd-associazione Medici Diabetologi ‘diabetes Cancer’ worki
* Diabetologists and Oncologists attitudes towards treating diabetes in the oncologic patient: Insights from an exploratory survey (256 views)
Diabetes Res Clin Pract (ISSN: 0168-8227linking), 2018 Sep; 143: 420-427.
Impact Factor: 3.639
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Sciacca MFM, Tempra C, Scollo F, Milardi D, La Rosa C
* Amyloid growth and membrane damage: Current themes and emerging perspectives from theory and experiments on Abeta and hIAPP (232 views) (PDF 107 views)
Bba-Gen Subjects (ISSN: 0005-2736print, 0005-2736linking), 2018 Mar 1; N/D: 1625-1638.
Impact Factor: 4.647
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Zampella E, Acampa W, Assante R, Nappi C, Gaudieri V, Mainolfi CG, Green R, Cantoni V, Panico M, Klain M, Petretta M, Slomka PJ, Cuocolo A
* Combined evaluation of regional coronary artery calcium and myocardial perfusion by (82)Rb PET/CT in the identification of obstructive coronary artery disease (525 views)
Eur J Nucl Med (ISSN: 1619-7089electronic, 1619-7070linking, 1619-7070print), 2018 Jan 25; 45(4): 521-529.
Impact Factor: 5.036
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Petretta M, Acampa W, Assante R, Zampella E, Nappi C, Petretta A, Cuocolo A
* My warranty has expired: I need to be retested (199 views)
J Nucl Cardiol (ISSN: 1532-6551electronic, 1071-3581linking), 2018 Jan 11; N/D: 1-9.
Impact Factor: 2.811
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Gaudieri V, Nappi C, Acampa W, Zampella E, Assante R, Mannarino T, Genova A, De Simini G, Klain M, Germano G, Petretta M, Cuocolo A
* Added prognostic value of left ventricular shape by gated SPECT imaging in patients with suspected coronary artery disease and normal myocardial perfusion (287 views)
J Nucl Cardiol (ISSN: 1071-3581, 1532-6551, 1532-6551electronic), 2017 Oct 25; N/D: N/D-N/D.
Impact Factor: 4.011
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Tumminia A, Milluzzo A, Cinti F, Parisi M, Tata F, Frasca F, Frittitta L, Vigneri R, Sciacca L
* Abnormal 1-hour post-load glycemia during pregnancy impairs post-partum metabolic status: a single-center experience (171 views)
J Endocrinol Invest (ISSN: 1720-8386, 0391-4097, 1720-8386electronic), 2017 Oct 24; N/D: N/D-N/D.
Impact Factor: 3.166
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Assante R, Acampa W, Zampella E, Arumugam P, Nappi C, Gaudieri V, Panico M, Magliulo M, Tonge CM, Petretta M, Cuocolo A
* Coronary atherosclerotic burden vs. coronary vascular function in diabetic and nondiabetic patients with normal myocardial perfusion: a propensity score analysis (348 views)
Eur J Nucl Med (ISSN: 1619-7070, 1619-7089, 1619-7070print), 2017 Mar 14; N/D: N/D-N/D.
Impact Factor: 7.704
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Monti SM, Supuran CT, De Simone G
* DPP-4 inhibitors: a patent review (2012 - 2014) (574 views)
Expert Opin Ther Pat (ISSN: 1354-3776, 1744-7674electronic), 2015 Feb; 25(2): 209-236.
Impact Factor: 4.626
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Tomasello MF, Sinopoli A, Pappalardo G
* On the Environmental Factors Affecting the Structural and Cytotoxic Properties of IAPP Peptides (443 views)
J Diabetes Res (ISSN: 2314-6745, 2314-6745print), 2015; articleID918573: 918573-918573.
Impact Factor: 2.431
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Coppo C, Bonfanti D, Bo S, Giordanino C, Gallo M, Cococcia S, Ciccone G, Smedile A, Ciancio A, Bugianesi E, Fagoonee S, Pellicano R, Rizzetto M, Saracco GM
* Risk of microangiopathy in type 2 diabetes mellitus patients with or without chronic hepatitis C: Results of a retrospective long-term controlled cohort study (303 views)
Dig Liver Dis (ISSN: 1590-8658, 1590-8658linking), 2015; 47(5): 405-410.
Impact Factor: 2.719
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Le Moli R, Muscia V, Tumminia A, Frittitta L, Buscema M, Palermo F, Sciacca L, Squatrito S, Vigneri R
* Type 2 diabetic patients with Graves' disease have more frequent and severe Graves' orbitopathy (896 views)
Nutrition (ISSN: 0939-4753, 1590-3729electronic), 2015; 25(5): 452-457.
Impact Factor: 3.39
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Petretta M, Acampa W, Cuocolo A
* Cardiovascular risk stratification in diabetic patients: is all in METS? (474 views)
J Nucl Cardiol (ISSN: 1071-3581, 1532-6551, 1532-6551electronic), 2014 Dec; 21(6): 1144-1147.
Impact Factor: 2.942
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Acampa W, Cantoni V, Green R, Maio F, Daniele S, Nappi C, Gaudieri V, Punzo G, Petretta M, Cuocolo A
* Prognostic value of normal stress myocardial perfusion imaging in diabetic patients: a meta-analysis (459 views)
J Nucl Cardiol (ISSN: 1071-3581, 1071-3581linking, 1532-6551), 2014 Oct; 21(5): 893-902.
Impact Factor: 2.942
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Acampa W, Petretta M, Cuocolo R, Daniele S, Cantoni V, Cuocolo A
* Warranty period of normal stress myocardial perfusion imaging in diabetic patients: A propensity score analysis (414 views)
J Nucl Cardiol (ISSN: 1071-3581, 1532-6551, 1532-6551electronic), 2014 Feb; 21(1): 50-56.
Impact Factor: 2.942
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Petretta M, Acampa W, Evangelista L, Daniele S, Zampella E, Assante R, Nappi C, Cantoni V, Fiumara G, Cuocolo A
* Reclassification of cardiovascular risk by myocardial perfusion imaging in diabetic patients with abnormal resting electrocardiogram (492 views)
Nutrition (ISSN: 0939-4753, 1590-3729electronic), 2014; 24(6): 588-593.
Impact Factor: 3.323
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Milardi D, Sciacca MF, Randazzo L, Raudino A, La Rosa C
* The role of calcium, lipid membranes and islet amyloid polypeptide in the onset of type 2 diabetes: Innocent bystanders or partners in a crime? (586 views)
Front Endocrinol (ISSN: 1664-2392, 1664-2392linking, 1664-2392print), 2014; 5(DEC): 216-216.
Impact Factor: 3.675
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Bellia F, GrassoG
* The role of copper(II) and zinc(II) in the degradation of human and murine IAPP by insulin-degrading enzyme (579 views)
J Mass Spectrom (ISSN: 1076-5174, 1096-9888), 2014; 49(4): 274-279.
Impact Factor: 2.379
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Ferro A, Petretta M, Acampa W, Fiumara G, Daniele S, Petretta MP, Cantoni V, Cuocolo A
* Post-stress left ventricular ejection fraction drop in patients with diabetes: A gated myocardial perfusion imaging study (436 views)
Bmc Cardiovasc Disor (ISSN: 1471-2261), 2013 Nov 14; 13: 99-99.
Impact Factor: 1.5
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Petretta M, Acampa W, Daniele S, Petretta MP, Plaitano M, Cuocolo A
* Transient ischemic dilation in patients with diabetes mellitus: prognostic value and effect on clinical outcome after coronary revascularization (346 views)
Circ Cardiovasc Imaging (ISSN: 1942-0080, 1941-9651), 2013 Nov; 6(6): 908-915.
Impact Factor: 1.783
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Petretta M, Fiumara G, Petretta MP, Cuocolo A
* Detection of silent myocardial ischemia: is it clinically relevant? (285 views)
J Nucl Cardiol (ISSN: 1532-6551, 1071-3581, 1532-6551electronic), 2013 Oct; 20(5): 707-710.
Impact Factor: 2.645
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Paolillo S, Rengo G, Pagano G, Pellegrino T, Savarese G, Femminella GD, Tuccillo M, Boemio A, Attena E, Formisano R, Petraglia L, Scopacasa F, Galasso G, Leosco D, Trimarco B, Cuocolo A, Perrone-Filardi P
* Impact of diabetes on cardiac sympathetic innervation in patients with heart failure: a 123I meta-iodobenzylguanidine (123I MIBG) scintigraphic study (314 views)
Diabetes Care (ISSN: 1935-5548, 0149-5992), 2013 Sep; 36(8): 2395-2401.
Impact Factor: 8.57
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Vitale M, Luongo D, Naviglio D, Bozzetto L, Mirabella M, Rivieccio AM, Giacco A, Rivellese AA
* Trans fatty acids consumption in type 1 diabetic patients: evaluation by dietary records and measurement in serum phospholipids (390 views)
Acta Diabetol (ISSN: 0940-5429, 1432-5233electronic), 2013 Aug; 50(4): 651-654.
Impact Factor: 3.679
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Mancini M, Masulli M, Liuzzi R, Mainenti PP, Ragucci M, Maurea S, Riccardi G, Vaccaro O
* Renal duplex sonographic evaluation of type 2 diabetic patients (453 views)
J Ultrasound Med (ISSN: 1550-9613, 0278-4297), 2013 Jun; 32(6): 1033-1040.
Impact Factor: 1.532
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Acampa W, Petretta M, Daniele S, Del Prete G, Assante R, Zampella E, Cuocolo A
* Incremental prognostic value of stress myocardial perfusion imaging in asymptomatic diabetic patients (453 views)
Atherosclerosis (ISSN: 0021-9150, 1879-1484), 2013 Apr; 227(2): 307-312.
Impact Factor: 3.971
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Paolillo S, Rengo G, Pagano G, Pellegrino T, Savarese G, Femminella GD, Tuccillo M, Boemio A, Attena E, Formisano R, Petraglia L, Scopacasa F, Galasso G, Leosco D, Trimarco B, Cuocolo A, Perrone-Filardi P
* IMPACT OF DIABETES MELLITUS IN IODINE-123 META-IODOBENZYLGUANIDINE (I123MIBG) CARDIAC UPTAKE IN PATIENTS WITH HEART FAILURE (263 views)
Journal Of The American College Of Cardiology (ISSN: 0735-1097), 2013 Mar 12; 61(10): 2395-2401.
Impact Factor: 15.343
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Petretta M, Acampa W, Daniele S, Petretta MP, Nappi C, Assante R, Zampella E, Costanzo P, Perrone-Filardi P, Cuocolo A
* Transient ischemic dilation in SPECT myocardial perfusion imaging for prediction of severe coronary artery disease in diabetic patients (703 views)
J Nucl Cardiol (ISSN: 1071-3581, 1532-6551, 1532-6551electronic), 2013 Feb; 20(1): 45-52.
Impact Factor: 2.645
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Petretta M, Acampa W, Fiumara G, Cuocolo A
* Cardiovascular risk stratification in diabetic patients (396 views)
Clin Transl Imaging (ISSN: 2281-5872, 2281-5872print, 2281-7565online), 2013; 1(5): 325-339.
Impact Factor: 0
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Bellia F, Pietropaolo A, Grasso G
* Formation of insulin fragments by insulin-degrading enzyme: The role of zinc(II) and cystine bridges (461 views)
J Mass Spectrom (ISSN: 1076-5174, 1096-9888), 2013; 48(2): 135-140.
Impact Factor: 2.709
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Giallauria F, Acampa W, Ricci F, Gallicchio R, Xhoxhi E, Vitelli A, D'Agostino M, Lucci R, Vigorito C, Cuocolo A
* Effects of exercise training started within 2 weeks after acute myocardial infarction on myocardial perfusion and left ventricular function: A gated SPECT imaging study (442 views)
Eur J Prev Cardiol (ISSN: 2047-4873, 2047-4881), 2012 Dec; 19(6): 1410-1419.
Impact Factor: 2.675
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Grasso G, Salomone F, Tundo GR, Pappalardo G, Ciaccio C, Spoto G, Pietropaolo A, Coletta M, Rizzarelli E
* Metal ions affect insulin-degrading enzyme activity (495 views)
J Chem Res (ISSN: 1873-3344, 0162-0134, 0162-0134print), 2012 Dec; 117: 351-358.
Impact Factor: 3.197
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Assante R, Petretta M, Acampa W, Daniele S, Nappi C, Zampella E, Perrone-Filardi P, Cuocolo A
* Prediction of Severe Coronary Artery Disease in Diabetic Patients with Gated SPECT Myocardial Perfusion Imaging (241 views)
Eur J Nucl Med (ISSN: 1619-7070, 1619-7089, 0340-6997), 2012 Oct; 39: N/D-N/D.
Impact Factor: 5.114
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Stanzione F, De Simone A, Esposito L, Vitagliano L
* Dynamical Properties of Steric Zipper Polymorphs Formed by a IAPP-Derived Peptide (462 views)
Protein Pept Lett (ISSN: 0929-8665, 1875-5305), 2012 Sep; 19(8): 846-851.
Impact Factor: 1.994
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Marciano C, Galderisi M, Gargiulo P, Acampa W, D'Amore C, Esposito R, Capasso E, Savarese G, Casaretti L, Lo Iudice F, Esposito G, Rengo G, Leosco D, Cuocolo A, Perrone-Filardi P
* Effects of type 2 diabetes mellitus on coronary microvascular function and myocardial perfusion in patients without obstructive coronary artery disease (932 views)
Eur J Nucl Med (ISSN: 1619-7070, 1619-7089, 0340-6997), 2012 Jul; 39(7): 1199-1206.
Impact Factor: 5.114
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Bozzetto L, Prinster A, Annuzzi G, Costagliola L, Mangione A, Vitelli A, Mazzarella R, Longobardo M, Mancini M, Vigorito C, Riccardi G, Rivellese AA
* Liver fat is reduced by an isoenergetic MUFA diet in a controlled randomized study in type 2 diabetic patients (940 views)
Diabetes Care (ISSN: 1935-5548, 0149-5992, 1935-5548electronic), 2012 Jul; 35(7): 1429-1435.
Impact Factor: 7.735
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Perrone-Filardi P, Musella F, Savarese G, Cecere M, Marciano C, Scala O, Rengo G, Dellegrottaglie S, Cuocolo A, Leosco D
* Coronary computed tomography: current role and future perspectives for cardiovascular risk stratification (482 views)
Eur Heart J-Card Img (ISSN: 2047-2412, 2047-2404, 2047-2412electronic), 2012 Jun; 13(6): 453-458.
Impact Factor: 3.669
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Franchin A, Corradin ML, Giantin V, Rossi F, Zanatta F, Attanasio F, Toffanello ED, Manzato E
* Diabetes in a geriatric ward: Efficacy and safety of new insulin analogs in very old inpatients (292 views)
Aging Clin Exp Res (ISSN: 1594-0667, 1720-8319), 2012 Jun; 24(SUPPL.3): 17-19.
Impact Factor: 1.006
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Acampa W, Petretta M, Evangelista L, Daniele S, Xhoxhi E, De Rimini ML, Cittanti C, Marranzano F, Spadafora M, Baldari S, Mansi L, Cuocolo A
* Myocardial perfusion imaging and risk classification for coronary heart disease in diabetic patients. The IDIS study: A prospective, multicentre trial (477 views)
Eur J Nucl Med (ISSN: 1619-7070, 1619-7089, 0340-6997), 2012 Mar; 39(3): 387-395.
Impact Factor: 5.114
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Berti V, Sciagrà R, Acampa W, Ricci F, Cerisano G, Gallicchio R, Vigorito C, Pupi A, Cuocolo A
* Relationship between infarct size and severity measured by gated SPECT and long-term left ventricular remodelling after acute myocardial infarction (548 views)
Eur J Nucl Med (ISSN: 1619-7070, 1619-7089, 0340-6997), 2011 Jun; 38(6): 1124-1131.
Impact Factor: 4.991
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Acampa W, Di Taranto MD, Morgante A, Salvatore B, Evangelista L, Ricci F, Costanzo P, De Sisto E, Filardi PP, Petretta M, Fortunato G, Cuocolo A
* C-reactive protein levels are associated with paraoxonase polymorphism L55M in patients undergoing cardiac SPECT imaging (387 views)
Scand J Clin Lab Invest (ISSN: 0036-5513, 1502-7686), 2011 May; 71(3): 179-184.
Impact Factor: 1.156
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Scognamiglio PL, Doti N, Grieco P, Pedone C, Ruvo M, Marasco D
* Discovery Of Small Peptide Antagonists Of Ped/Pea15-D4alpha Interaction From Simplified Combinatorial Libraries (504 views)
Chem Biol Drug Des (ISSN: 1747-0277, 1747-0285), 2011 May; 77(5): 319-327.
Impact Factor: 2.282
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Striano P, Caranci F, Pappata S, Zara F, Striano S
* Hemidystonia in uncontrolled type 2 diabetes mellitus (291 views)
Arch Neurol (ISSN: 1538-3687electronic, 0003-9942linking), 2011 May; 68(5): 674-675.
Impact Factor: 7.584
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Berti V, Ricci F, Gallicchio R, Acampa W, Cerisano G, Vigorito C, Sciagra'R, Pupi A, Cuocolo A
* Infarct Size And Severity Measured By Gated Spect For Predicting The Long-Term Left Ventricular Remodelling After Acute Myocardial Infarction (241 views)
European Heart Journal Supplements, 2011 Apr; 4: N/D-N/D.
Impact Factor: 14.723
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Bozzetto L, Prinster A, Mancini M, Giacco R, De Natale C, Salvatore M, Riccardi G, Rivellese AA, Annuzzi G
* Liver fat in obesity: role of type 2 diabetes mellitus and adipose tissue distribution (461 views)
Eur J Clin Invest (ISSN: 0014-2972, 1365-2362, 0014-2972linking), 2011 Jan; 41(1): 39-44.
Impact Factor: 3.018
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Milardi D, Sciacca MFM, Pappalardo M, Grasso DM, La Rosa C
* The Role Of Aromatic Side-Chains In Amyloid Growth And Membrane Interaction Of The Islet Amyloid Polypeptide Fragment Lanflvh (458 views)
Eur Biophys J, 2011 Jan; 40(1): 1-12.
Impact Factor: 3.832
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Spadafora M, Varrella P, Acampa W, Spirito M, Nappi C, Mansi L, Miletto P, Rosato G, Cuocolo A
* Direct imaging of viable myocardium by gated SPECT in patients with ischaemic left ventricular dysfunction (417 views)
Eur J Nucl Med (ISSN: 1619-7070, 1619-7089, 0340-6997), 2010 Sep; 37(9): 1730-1735.
Impact Factor: 5.036
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Bombardieri E, Ambrosini V, Aktolun C, Baum RP, Bishof-delaloye A, Del Vecchio S, Maffioli L, Mortelmans L, Oyen W, Pepe G, Chiti A
* In-111-pentetreotide scintigraphy: procedure guidelines for tumour imaging (479 views)
Eur J Nucl Med (ISSN: 1619-7070, 1619-7089, 0340-6997), 2010 Jul; 37(7): 1441-1448.
Impact Factor: 5.036
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Cuocolo A, Petretta M, Acampa W, De Falco T
* Gated SPECT myocardial perfusion imaging: The further improvements of an excellent tool (376 views)
Q J Nucl Med Mol Im (ISSN: 1824-4785, 1824-4478, 1824-4785linking), 2010 Apr; 54(2): 129-144.
Impact Factor: 1.724
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Giacco R, Clemente G, Cipriano D, Luongo D, Viscovo D, Patti L, Di Marino L, Giacco A, Naviglio D, Bianchi MA, Ciati R, Brighenti F, Rivellese AA, Riccardi G
* Effects of the regular consumption of wholemeal wheat foods on cardiovascular risk factors in healthy people (950 views)
Nutrition (ISSN: 0939-4753, 1590-3729electronic), 2010 Mar; 20(3): 186-194.
Impact Factor: 3.438
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Acampa W, Caprio MG, Nicolai E, Liuzzi R, Capasso E, Luongo L, Petretta M, Cuocolo A
* Assessment of poststress left ventricular ejection fraction by gated SPECT: Comparison with equilibrium radionuclide angiocardiography (475 views)
Eur J Nucl Med (ISSN: 1619-7070, 1619-7089, 0340-6997), 2010 Feb; 37(2): 349-356.
Impact Factor: 5.036
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Capaccio D, Ciccodicola A, Sabatino L, Casamassimi A, Pancione M, Fucci A, Febbraro, Merlino A, Graziano G, Colantuoni V
* A novel germline mutation in Peroxisome Proliferator-Activated Receptor γ gene associated with large intestine polyp formation and dyslipidemia (431 views)
Bba-Gen Subjects (ISSN: 0925-4439, 0006-3002, 1570-9639), 2010; 1802(6): 572-581.
Impact Factor: 2.773
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Cuocolo A, Concilio C, Acampa W, Ferro A, Evangelista L, Daniele S, Petretta M
* Cardiovascular risk stratification of diabetic patients (591 views)
Minerva Endocrinol (ISSN: 0391-1977, 1827-1634electronic, 0391-1977linking), 2009 Sep; 34(3): 205-221.
Impact Factor: 1.464
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Palladino P, Ronga L, Benedetti E, Rossi F, Ragone R
* Peptide Fragment Approach to Prion Misfolding: The Alpha-2 Domain (402 views)
Int J Pept Res Ther (ISSN: 1573-3149, 0929-5666), 2009 Sep; 15(3): 165-176.
Impact Factor: 0.869
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Masulli M, Mancini M, Liuzzi R, Daniele S, Mainenti PP, Vergara E, Genovese S, Salvatore M, Vaccaro O
* Measurement of the intrarenal arterial resistance index for the identification and prediction of diabetic nephropathy (700 views)
Nutrition (ISSN: 0939-4753, 1590-3729electronic, 0939-4753linking), 2009 Jun; 19(5): 358-364.
Impact Factor: 3.517
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Sandomenico A, Monti SM, Sabatella M, De Capua A, Tornatore L, Doti N, Viparelli F, Dathan NA, Pedone C, Ruvo M, Marasco D
* Protein-protein interactions: a simple strategy to identify binding sites and peptide antagonists (607 views)
Chem Biol Drug Des (ISSN: 1747-0285, 1747-0277), 2009 May; 73(5): 483-493.
Impact Factor: 2.473
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De Simone G, Supuran CT
* Drug Design of Antiobesity Carbonic Anhydrase Inhibitors (336 views)
Drug Des Of Zinc Enzyme Inhibitors (ISSN: 9780-4702, 9780-470275009), 2009; 66(DECEMBERSPEC.I): 241-254.
Impact Factor: 1.156
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Milardi D, Pappalardo M, Pannuzzo M, Grasso DM, Rosa CL
* The role of the Cys2-Cys7 disulfide bridge in the early steps of Islet amyloid polypeptide aggregation: A molecular dynamics study (447 views)
Chem Phys Lett (ISSN: 0009-2614), 2008 Oct 1; 463(4-6): 396-399.
Impact Factor: 2.169
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Ferro A, Costanzo P, Acampa W, Daniele S, Evangelista L, De Marino M, Ricci F, Vassallo S, Petretta M, Cuocolo A
* The IDIS Investigators: Combined Evaluation of Myocardial Perfusion and Left Ventricular Function by Gated SPECT Predicts Severe Coronary Artery Disease in Diabetic Patients (253 views)
Eur J Nucl Med (ISSN: 1619-7070, 1619-7089, 0340-6997), 2008 Oct; 35: N/D-N/D.
Impact Factor: 4.532
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Sciacca MFM, Pappalardo M, Milardi D, Grasso DM, La Rosa C
* Calcium-Activated Membrane Interaction Of The Islet Amyloid Polypeptide: Implications In The Pathogenesis Of Type Ii Diabetes Mellitus (1045 views)
Arch Biochem Biophys, 2008 Sep 15; 65(1-2): 291-298.
Impact Factor: 3.043
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Viparelli F, Cassese A, Doti N, Paturzo F, Marasco D, Dathan NA, Monti SM, Basile G, Ungaro P, Sabatella M, Miele C, Teperino R, Consiglio E, Pedone C, Beguinot F, Formisano P, Ruvo M
* Targeting of PED/PEA-15 molecular interaction with phospholipase D1 enhances insulin sensitivity in skeletal muscle cells (437 views)
Jbc Papers (ISSN: 0021-9258, 1083-351x, 0021-9258linking), 2008 Sep 1; 283(31): 21769-21778.
Impact Factor: 5.52
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Acampa W, Petretta M, Evangelista L, Nappi G, Luongo L, Petretta MP, Cuocolo A
* Stress cardiac single-photon emission computed tomographic imaging late after coronary artery bypass surgery for risk stratification and estimation of time to cardiac events (325 views)
J Thorac Cardiovasc Surg (ISSN: 0022-5223, 1097-685x), 2008 Jul; 136(1): 46-51.
Impact Factor: 3.037
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Petretta M, Soricelli A, Storto G, Cuocolo A
* Assessment of coronary flow reserve using single photon emission computed tomography with technetium 99m-labeled tracers (587 views)
J Nucl Cardiol (ISSN: 1532-6551, 1071-3581, 1532-6551electronic), 2008 May; 15(3): 456-465.
Impact Factor: 2.442
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Goldfine ID, Maddux BA, Youngren JF, Reaven G, Accili D, Trischitta V, Vigneri R, Frittitta L
* The role of membrane glycoprotein plasma cell antigen 1 ectonucleotide pyrophosphatase phosphodiesterase 1 in the pathogenesis of insulin resistance and related abnormalities (1197 views)
Endocrine Reviews (ISSN: 0163-769x), 2008 Feb; 29(1): 62-75.
Impact Factor: 18.562
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Petretta M, Acampa W, Evangelista L, Daniele S, Ferro A, Cuocolo A
* Impact of inducible ischemia by stress SPECT in cardiac risk assessment in diabetic patients: Rationale and design of a prospective, multicenter trial (310 views)
J Nucl Cardiol (ISSN: 1071-3581, 1532-6551, 1532-6551electronic), 2008 Jan; 15(1): 100-104.
Impact Factor: 2.442
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Sorrentino AR, Acampa W, Petretta M, Mainolfi C, Salvatore M, Cuocolo A
* Comparison of the prognostic value of SPECT after nitrate administration and metabolic imaging by PET in patients with ischaemic left ventricular dysfunction (337 views)
Eur J Nucl Med (ISSN: 1619-7070, 1619-7089, 0340-6997), 2007 Apr; 34(4): 558-562.
Impact Factor: 4.101
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Storto G, Pellegrino T, Sorrentino AR, Luongo L, Petretta M, Cuocolo A
* Estimation of coronary flow reserve by sestamibi imaging in type 2 diabetic patients with normal coronary arteries (398 views)
J Nucl Cardiol (ISSN: 1532-6551, 1071-3581, 1532-6551electronic), 2007 Apr; 14(2): 194-199.
Impact Factor: 2.359
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Evangelista L, Ferro A, Acampa W, Capasso R, De Rimini ML, Cittanti C, Marranzano F, Spadafora M, Baldari S, Mansi L, Petretta M, Cuocolo A
* A prospective, multi-center trial to assess the prevalence and the clinical predictors of myocardial ischemia in patients presenting with diabetes mellitus and suspected or documented coronary artery disease (237 views)
Eur J Nucl Med (ISSN: 1619-7070, 1619-7089, 0340-6997), 2006 Sep; 33: N/D-N/D.
Impact Factor: 4.041
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Di Bonito P, Rinaldi M, Genovese S, Parillo M, Gruppo di studio regionale FADOI, Lucibelli L, Miano P, Piantadosi S, Sassi G, Caiazzo G, Marrone G, De Feo EM, Piscopo G, Di Domenico A, Visconti M, Nicoletti A, Luca S, Cunzolo D, Cianciullo M, Tortora A, Zinno A, D’Auria S, Rinaldi C, Pascucci D, Gennaro MD, Zerella F, Forte R, Grimaldi U, Foschi A, Boniello B, Garrulo A, Pontieri A, Dello Iacono N, Mancini M, D’avanzo A, Di Guglielmo G, Sossio F
* Known And Unknown Diabetes Mellitus Among Patients Hositalized In Internal Medicine Units Of The Campania Region (southern Italy) (237 views)
G It Diabetol Metab, 2006; 26: 5-9.
Impact Factor: 0
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Colao A, Di Somma C, Cuocolo A, Spinelli L, Acampa W, Spiezia S, Rota F, Savanelli MC, Lombardi G
* Does a gender-related effect of growth hormone (GH) replacement exist on cardiovascular risk factors, cardiac morphology, and performance and atherosclerosis? Results of a two-year open, prospective study in young adult men and women with severe GH deficiency (450 views)
J Clin Endocrinol Metab (ISSN: 0021-972x), 2005 Sep; 90(9): 5146-5155.
Impact Factor: 6.02
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Vicario MLE, Cirillo L, Storto G, Pellegrino T, Ragone N, Fontanella L, Petretta M, Bonaduce D, Cuocolo A
* Influence of risk factors on coronary flow reserve in patients with 1-vessel coronary artery disease (365 views)
J Nucl Med (ISSN: 0161-5505, 1535-5667, 1535-5667electronic), 2005 Sep; 46(9): 1438-1443.
Impact Factor: 4.684
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Foti D, Chiefari E, Fedele M, Iuliano R, Brunetti L, Paonessa F, Manfioletti G, Barbetti F, Brunetti A, Croce CM, Fusco A, Brunetti A
* Lack of the architectural factor HMGA1 causes insulin resistance and diabetes in humans and mice (391 views)
Nat Med (ISSN: 1078-8956, 0034-7264), 2005 Jul; 11(7): 765-773.
Impact Factor: 28.878
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Petretta M, Storto G, Acampa W, Sansone V, Evangelista L, Spinelli L, Cuocolo A
* Relation between wall thickening on gated perfusion SPECT and functional recovery after coronary revascularization in patients with previous myocardial infarction (372 views)
Eur J Nucl Med (ISSN: 1619-7070, 1619-7089, 0340-6997), 2004 Dec; 31(12): 1599-1605.
Impact Factor: 3.935
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Clemente G, Mancini M, Nazzaro F, Lasorella G, Rivieccio A, Palumbo AM, Rivellese AA, Ferrara L, Giacco R
* Effects of different dairy products on postprandial lipemia (1088 views)
Nutrition (ISSN: 0939-4753, 1590-3729electronic), 2003 Dec; 13(6): 377-383.
Impact Factor: 2.148
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Spinelli L, Petretta M, Acampa W, He W, Petretta A, Bonaduce D, Cuocolo A
* Prognostic value of combined assessment of regional left ventricular function and myocardial perfusion by dobutamine and rest gated SPECT in patients with uncomplicated acute myocardial infarction (429 views)
J Nucl Med (ISSN: 0161-5505, 1535-5667, 1535-5667electronic), 2003 Jul; 44(7): 1023-1029.
Impact Factor: 4.899
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Pauciullo P, Giannino A, De Michele M, Gentile M, Liguori R, Argiriou A, Carlotto A, Faccenda F, Mancini M, Bond MG, De Simone V, Rubba P
* Increased carotid artery intima-media thickness is associated with a novel mutation of low-density lipoprotein receptor independently of major cardiovascular risk factors (735 views)
Metab Clin Exp (ISSN: 0026-0495, 1532-8600), 2003; 52(11): 1433-1438.
Impact Factor: 2.013
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Colao A, Di Somma C, Cuocolo A, Spinelli L, Tedesco N, Pivonello R, Bonaduce D, Salvatore M, Lombardi G
* Improved cardiovascular risk factors and cardiac performance after 12 months of growth hormone (GH) replacement in young adult patients, with GH deficiency (634 views)
J Clin Endocrinol Metab (ISSN: 0021-972x), 2001 May; 86(5): 1874-1881.
Impact Factor: 5.16
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Tedeschi E, Marano I, Savarese F, Olibet G, Di Salvo E, Brunetti A, Sodano A
Neurological deficit following spinal anaesthesia: MRI and CT evidence of spinal cord gas embolism (371 views)
Neuroradiology (ISSN: 0028-3940, 1432-1920electronic, 0028-3940linking), 1999 Apr; 41(4): 275-278.
Impact Factor: 1.287
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Giacco R, Mancini M, Clemente G, Coppola S, Lasorella G, D’Avanzo G, Rivieccio A M, Ruffa G, Brighenti F, Rivellese AA, Riccardi G
Metabolic effects of resistant starch in patients with Type 2 diabetes (527 views)
Diabetes Nutr Metab Clin Exp (ISSN: 0394-3402), 1998; 11(6): 330-335.
Impact Factor: 0.629
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Ferrara LA, Iannuzzi R, Gaeta I, Mancini M, Guida L, Marotta T
Left ventricular hypertrophy and hypertension (369 views)
Clin Exp Hypertens Informa Healthcare, 1996 Jul; 15(6): 1025-1032.
Impact Factor: 0
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Ferrara LA, Mancini M, Celentano A, Galderisi M, Iannuzzi R, Marotta T, Gaeta I
Early changes of the arterial carotid wall in uncomplicated primary hypertensive patients: Study by ultrasound high-resolution B-mode imaging (284 views)
Arterioscler Thromb Vasc Biol Arteriosclerosis Thrombosis And Vascular Biology (ISSN: 1079-5642, 1049-8834), 1994 Sep; 14(8): 1290-1296.
Impact Factor: 5.317
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Manna R, Salvatore M, Di Leo MA, Scuderi F, Greco AV, Ghirlanda G, Gambassi G
Relationship between urinary neopterin excretion and islet cell antibodies in type 1 (insulin-dependent) diabetes (432 views)
Diabetes Res (ISSN: 0265-5985), 1991 May; 17(1): 33-36.
Impact Factor: 0
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Benzi L, Trischitta V, Ciccarone A, Cecchetti P, Brunetti A, Squatrito S, Marchetti P, Vigneri R, Navalesi R
Improvement with metformin in insulin internalization and processing in monocytes from NIDDM patients (254 views)
Diabetesdiabetes (ISSN: 0012-1797), 1990 Jul; 39(7): 844-849.
Impact Factor: 8.675
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Ferrara LA, Iannuzzi R, Mancini M, Iannuzzi A, Celentano A, Galderisi M
Peripheral Arterial Haemodinamics In Primary Hypertension: Influences Of Other Cardiovascular Risk Factors (303 views)
American Journal Of Hypertension 3, 1990; N/D: 110A-110A.
Impact Factor: 0
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Trischitta V, Brunetti A, Chiavetta A, Benzi L, Papa V, Vigneri R
Defects in insulin-receptor internalization and processing in monocytes of obese subjects and obese NIDDM patients (314 views)
Diabetesdiabetes (ISSN: 0012-1797), 1989 Dec; 38(12): 1579-1584.
Impact Factor: 8.675
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Manna R, Salvatore M, Scuderi F, Papa G, Marietti G, Greco AV, Ghirlanda G, Gambassi G
Negative correlation between ICA persistence and beta cell restoration after IDDM diagnosis (318 views)
Diabetes Res (ISSN: 0265-5985), 1988 Nov; 9(3): 101-103.
Impact Factor: 0
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Trischitta V, Benzi L, Brunetti A, Cecchetti P, Marchetti P, Vigneri R, Navalesi R
Intracellular insulin processing is altered in monocytes from patients with type II diabetes mellitus (971 views)
J Clin Endocrinol Metab (ISSN: 0021-972x), 1987 May; 64(5): 914-920.
Impact Factor: 4.575
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88 Records (80 excluding Abstracts).
Total impact factor: 360.651 (324.347 excluding Abstracts).
Total 5 year impact factor: 347.812 (315.725 excluding Abstracts).
Total impact factor: 360.651 (324.347 excluding Abstracts).
Total 5 year impact factor: 347.812 (315.725 excluding Abstracts).
592 views. Last view on Sunday 07 May 2023, 11:21:34
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