Real-life management and outcome of thyroid carcinoma-related bone metastases: results from a nationwide multicenter experience (702 views)
Endocrine (ISSN: 1355-008x, 1355-008xlinking), 2017 Nov 06; 59(1): 90-101.
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Paper type: Journal Article, Multicenter Study, Observational Study,
Impact factor: 3.179, 5-year impact factor: 3.057
Url: https://www.scopus.com/inward/record.uri?eid=2-s2.0-85033432983&doi=10.1007%2fs12020-017-1455-6&partnerID=40&md5=d29ed58e9e27bb8fc9d07f6bdb32f17e
Keywords: Bone Metastases, Denosumab-Radioiodine, Thyroid Carcinoma, Zoledronate, Radioactive Iodine, Zoledronic Acid, Adolescent, Adult, Aged, Article, Bone Biopsy, Cancer Localization, Cancer Mortality, Cancer Surgery, Cause Of Death, Child, Cohort Analysis, Computer Assisted Tomography, Controlled Study, Differentiated Thyroid Cancer, Disease Association, External Beam Radiotherapy, Female, Hazard Ratio, Human, Hypercalcemia, Informed Consent, Major Clinical Study, Multicenter Study, Nuclear Magnetic Resonance Imaging, Observational Study, Pathologic Fracture, Positron Emission Tomography, Practice Guideline, Priority Journal, Retrospective Study, Spinal Cord Compression, Bone Tumor, Clinical Trial, Middle Aged, Prognosis, Secondary, Thyroid Tumor, Treatment Outcome, Very Elderly, Young Adult, 80 And Over, Bone Neoplasms, Retrospective Studies, Thyroid Neoplasms, Diagnosis, Epidemiology, Bone Neoplasms Diagnosis Epidemiology Secondary Therapy , Thyroid Neoplasms Diagnosis Epidemiology Pathology Therapy,
Affiliations:
*** IBB - CNR ***
Endocrine Unit, ASST Carlo Poma, Mantua, Italy., Department of Molecular and Translational Medicine, University of Brescia, Brescia, Italy., Nuclear Medicine, ASST Spedali Civili of Brescia, Brescia, Italy., Nuclear Medicine, University of Brescia, Brescia, Italy., Oncological Endocrinology, University of Turin, Torino, Italy., Nuclear Medicine, Humanitas Research Hospital and Humanitas University, Milan, Italy., Nuclear Medicine, University of Naples Federico II, Napoli, Italy., Nuclear Medicine, "S. Maria della Misericordia" Hospital, Perugia, Italy., Internal Medicine, University Sapienza of Rome, Roma, Italy., Endocrinology Unit, Department of Clinical and Experimental Medicine, University of Pisa, Pisa, Italy., Nuclear Medicine, Azienda Ospedaliera Santa Maria Nuova-IRCCS Reggio Emilia, Reggio Emilia, Italy., Department of Medicine and Surgery, University of Salerno, Fisciano, Italy., Institute of Biostructure and Bioimaging of the National Research Council of Italy-CNR, Naples, Italy., Nuclear Medicine, Catholic University of Sacred Heart, Rome, Italy., San Raffaele Vita-Salute University, Milan, Italy., Medical Oncology, Department of Medical and Surgical Specialties, Radiological Sciences, and Public Health, University of Brescia, Brescia, Italy., San Raffaele Vita-Salute University, Milan, Italy. giustina.andrea@hsr.it.,
Nuclear Medicine, “S. Maria della Misericordia” Hospital, Perugia, Italy
Department of Molecular and Translational Medicine, University of Brescia, Brescia, Italy.
Nuclear Medicine, ASST Spedali Civili of Brescia, Brescia, Italy.
Nuclear Medicine, University of Brescia, Brescia, Italy.
Oncological Endocrinology, University of Turin, Torino, Italy.
Nuclear Medicine, Humanitas Research Hospital and Humanitas University, Milan, Italy.
Nuclear Medicine, "S. Maria della Misericordia" Hospital, Perugia, Italy.
Internal Medicine, University Sapienza of Rome, Roma, Italy.
Endocrinology Unit, Department of Clinical and Experimental Medicine, University of
References:
Not available.
Endocrine (ISSN: 1355-008x, 1355-008xlinking), 2017 Nov 06; 59(1): 90-101.
Export to BibTeX Export to EndNote
Paper type: Journal Article, Multicenter Study, Observational Study,
Impact factor: 3.179, 5-year impact factor: 3.057
Url: https://www.scopus.com/inward/record.uri?eid=2-s2.0-85033432983&doi=10.1007%2fs12020-017-1455-6&partnerID=40&md5=d29ed58e9e27bb8fc9d07f6bdb32f17e
Keywords: Bone Metastases, Denosumab-Radioiodine, Thyroid Carcinoma, Zoledronate, Radioactive Iodine, Zoledronic Acid, Adolescent, Adult, Aged, Article, Bone Biopsy, Cancer Localization, Cancer Mortality, Cancer Surgery, Cause Of Death, Child, Cohort Analysis, Computer Assisted Tomography, Controlled Study, Differentiated Thyroid Cancer, Disease Association, External Beam Radiotherapy, Female, Hazard Ratio, Human, Hypercalcemia, Informed Consent, Major Clinical Study, Multicenter Study, Nuclear Magnetic Resonance Imaging, Observational Study, Pathologic Fracture, Positron Emission Tomography, Practice Guideline, Priority Journal, Retrospective Study, Spinal Cord Compression, Bone Tumor, Clinical Trial, Middle Aged, Prognosis, Secondary, Thyroid Tumor, Treatment Outcome, Very Elderly, Young Adult, 80 And Over, Bone Neoplasms, Retrospective Studies, Thyroid Neoplasms, Diagnosis, Epidemiology, Bone Neoplasms Diagnosis Epidemiology Secondary Therapy , Thyroid Neoplasms Diagnosis Epidemiology Pathology Therapy,
Affiliations:
*** IBB - CNR ***
Endocrine Unit, ASST Carlo Poma, Mantua, Italy., Department of Molecular and Translational Medicine, University of Brescia, Brescia, Italy., Nuclear Medicine, ASST Spedali Civili of Brescia, Brescia, Italy., Nuclear Medicine, University of Brescia, Brescia, Italy., Oncological Endocrinology, University of Turin, Torino, Italy., Nuclear Medicine, Humanitas Research Hospital and Humanitas University, Milan, Italy., Nuclear Medicine, University of Naples Federico II, Napoli, Italy., Nuclear Medicine, "S. Maria della Misericordia" Hospital, Perugia, Italy., Internal Medicine, University Sapienza of Rome, Roma, Italy., Endocrinology Unit, Department of Clinical and Experimental Medicine, University of Pisa, Pisa, Italy., Nuclear Medicine, Azienda Ospedaliera Santa Maria Nuova-IRCCS Reggio Emilia, Reggio Emilia, Italy., Department of Medicine and Surgery, University of Salerno, Fisciano, Italy., Institute of Biostructure and Bioimaging of the National Research Council of Italy-CNR, Naples, Italy., Nuclear Medicine, Catholic University of Sacred Heart, Rome, Italy., San Raffaele Vita-Salute University, Milan, Italy., Medical Oncology, Department of Medical and Surgical Specialties, Radiological Sciences, and Public Health, University of Brescia, Brescia, Italy., San Raffaele Vita-Salute University, Milan, Italy. giustina.andrea@hsr.it.,
Nuclear Medicine, “S. Maria della Misericordia” Hospital, Perugia, Italy
Department of Molecular and Translational Medicine, University of Brescia, Brescia, Italy.
Nuclear Medicine, ASST Spedali Civili of Brescia, Brescia, Italy.
Nuclear Medicine, University of Brescia, Brescia, Italy.
Oncological Endocrinology, University of Turin, Torino, Italy.
Nuclear Medicine, Humanitas Research Hospital and Humanitas University, Milan, Italy.
Nuclear Medicine, "S. Maria della Misericordia" Hospital, Perugia, Italy.
Internal Medicine, University Sapienza of Rome, Roma, Italy.
Endocrinology Unit, Department of Clinical and Experimental Medicine, University of
References:
Not available.
Real-life management and outcome of thyroid carcinoma-related bone metastases: results from a nationwide multicenter experience
Purpose and Patients: The M.O.S.CA.TI. (Metastases of the Skeleton from CArcinoma of the ThyroId) is a multicenter, retrospective study investigating the real-life outcome and management of bone metastases (BM) in 143 patients (63 M, 80 F; median age 64 years, range 11–87) with differentiated thyroid carcinoma (DTC). Results: Radio-active iodine (RAI) treatment was performed in 131 patients (91.6%), surgical approach and/or external radiotherapy in 68 patients (47.6%), and anti-resorptive bone-active drugs in 32 patients (22.4%; in 31 zoledronate and in one denosumab). At the start of treatment, 24 patients (75.0%) receiving anti-resorptive bone-active drugs had at least one clinical skeletal-related event (SRE) (p < 0.001). One or more clinical SREs (pathological fractures and/or malignant hypercalcemia and/or spinal cord compression) developed in 53 patients (37.1%). Development of SREs was significantly associated with metachronous BM (hazard ratio (HR) 2.04; p = 0.04), localization of BM to cervical spine (HR 3.89; p = 0.01), and lack of avid RAI uptake (HR 2.66; p = 0.02). Thirty-nine patients (27.3%) died in correlation with development of SREs (HR 6.97; p = 0.006) and localization of BM to the hip (HR 3.86; p = 0.02). Moreover, overall mortality was significantly decreased by RAI therapy (HR 0.10; p = 0.02), whereas no significant effects were induced by bone-active drugs (p = 0.36), external radiotherapy (p = 0.54), and surgery (p = 0.43) of BM. Conclusions: SREs are very frequent in BM from DTC and they impact patient survival. In the real life, the use of bone-active drugs is currently limited to zoledronate in patients with pre-existing SREs. In this clinical setting, RAI therapy, but not zoledronate, decreased mortality. © 2017, Springer Science+Business Media, LLC.
Purpose and Patients: The M.O.S.CA.TI. (Metastases of the Skeleton from CArcinoma of the ThyroId) is a multicenter, retrospective study investigating the real-life outcome and management of bone metastases (BM) in 143 patients (63 M, 80 F; median age 64 years, range 11–87) with differentiated thyroid carcinoma (DTC). Results: Radio-active iodine (RAI) treatment was performed in 131 patients (91.6%), surgical approach and/or external radiotherapy in 68 patients (47.6%), and anti-resorptive bone-active drugs in 32 patients (22.4%; in 31 zoledronate and in one denosumab). At the start of treatment, 24 patients (75.0%) receiving anti-resorptive bone-active drugs had at least one clinical skeletal-related event (SRE) (p < 0.001). One or more clinical SREs (pathological fractures and/or malignant hypercalcemia and/or spinal cord compression) developed in 53 patients (37.1%). Development of SREs was significantly associated with metachronous BM (hazard ratio (HR) 2.04; p = 0.04), localization of BM to cervical spine (HR 3.89; p = 0.01), and lack of avid RAI uptake (HR 2.66; p = 0.02). Thirty-nine patients (27.3%) died in correlation with development of SREs (HR 6.97; p = 0.006) and localization of BM to the hip (HR 3.86; p = 0.02). Moreover, overall mortality was significantly decreased by RAI therapy (HR 0.10; p = 0.02), whereas no significant effects were induced by bone-active drugs (p = 0.36), external radiotherapy (p = 0.54), and surgery (p = 0.43) of BM. Conclusions: SREs are very frequent in BM from DTC and they impact patient survival. In the real life, the use of bone-active drugs is currently limited to zoledronate in patients with pre-existing SREs. In this clinical setting, RAI therapy, but not zoledronate, decreased mortality. © 2017, Springer Science+Business Media, LLC.
Real-life management and outcome of thyroid carcinoma-related bone metastases: results from a nationwide multicenter experience
| ▼ Clinical Oncology |
Real-life management and outcome of thyroid carcinoma-related bone metastases: results from a nationwide multicenter experience
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Maurea S, Cuocolo A, Reynolds J, Keiser H, Neumann R, Salvatore M
Iodine-131 metaiodobenzylguanidine scintigraphy in the evaluation of paragangliomas. Comparison between benign and malignant tumors (604 views)
Radiol Med (ISSN: 0033-8362, 1826-6983, 1826-6983electronic), 1994; 87(5): 688-693.
Impact Factor: 0.967
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Maurea S, Maurelli L, Lastoria S, Cuocolo A, Brunetti A, Pace L, Caracò C, Klain M, Lupoli G, Salvatore M
Familial pheochromocytoma in Sipple's syndrome. A comparison between scintigraphy with 131I-meta-iodobenzylguanidine, computed tomography and echography (516 views)
Radiol Med (ISSN: 0033-8362, 1826-6983, 1826-6983electronic), 1992; 83(4): 486-490.
Impact Factor: 0.967
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Maurelli L, Cuocolo A, Lastoria S, Brunetti A, Maurea S, Lembo G, Klain M, Carac C, Salvatore M
131I-meta-iodobenzylguanidine scintigraphy in patients with a suspected pheochromocytoma. A comparison with CT and biohumoral parameters (1270 views)
Radiol Med (ISSN: 0033-8362, 1826-6983, 1826-6983electronic), 1991; 82(6): 839-843.
Impact Factor: 0.967
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Marchetti P, Benzi L, Trischitta V, Brunetti A, Cecchetti P, Ciccarone AM, Pezzino V, Vigneri R, Navalesi R
Complementary use of gel permeation and reversed-phase liquid chromatography for the analysis of A14-[125I]insulin and its degradation products in isolated human monocytes (2025 views)
J Chromatogr B Biomed Sci Appl (ISSN: 0378-4347), 1986 Apr 25; 377(C): 339-344.
Impact Factor: 1.588
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* Radium-223 for the treatment of bone metastases in castration-resistant prostate cancer: when and why (463 views)
Tumori (ISSN: 0300-8916linking, 0300-8916print), 2019 May 16; N/D: 300891619851376-300891619851376.
Impact Factor: 1.304
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Orlandella FM, Mariniello RM, Iervolino PLC, Auletta L, De Stefano AE, Ugolini C, Greco A, Mirabelli P, Pane K, Franzese M, Denaro M, Basolo F, Salvatore G
* Junctional adhesion molecule-A is down-regulated in anaplastic thyroid carcinomas and reduces cancer cell aggressiveness by modulating p53 and GSK3 alpha/beta pathways (445 views)
Mol Carcinog (ISSN: 0899-1987linking), 2019 Mar 4; 58(7): 1181-1193.
Impact Factor: 3.851
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Russo M, Malandrino P, Moleti M, Vermiglio F, Violi MA, Marturano I, Minaldi E, Vigneri R, Pellegriti G, Regalbuto C
* Tall cell and diffuse sclerosing variants of papillary thyroid cancer: outcome and predicting value of risk stratification methods (613 views)
J Endocrinol Invest (ISSN: 1720-8386, 0391-4097, 1720-8386electronic), 2017 May 20; 40(11): 1235-1241.
Impact Factor: 3.166
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Greco A, Albanese S, Auletta L, Mirabelli P, Zannetti A, D'Alterio C, Di Maro G, Orlandella FM, Salvatore G, Soricelli A, Salvatore M
* High-frequency ultrasound-guided injection for the generation of a novel orthotopic mouse model of human thyroid carcinoma (1013 views)
Thyroid (ISSN: 1050-7256, 1050-7256linking), 2016 Feb 4; 26(4): 552-558.
Impact Factor: 5.515
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De Luca S, Fonti R, Camera L, Salvatore B, Faggiano A, Ciarmiello A, Segreto S, Colao A, Salvatore M, Del Vecchio S
* Multimodal imaging with (18)F-FDG-PET/CT and (111)In-Octreotide SPECT in patients with metastatic medullary thyroid carcinoma (699 views)
Ann Nucl Med (ISSN: 0914-7187, 1864-6433, 0914-7187linking), 2016 Jan 11; 30(3): 1-8.
Impact Factor: 1.396
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Albanese S, Auletta L, Zannetti A, Di Maro G, Mirabelli P, D'Alterio C, Salvatore G, Soricelli A, Salvatore M, Greco A
* High Frequency Ultrasound for the development of an Orthotopic mouse model of Human Follicular Thyroid Carcinoma (614 views)
Eur J Nucl Med (ISSN: 1619-7070, 1619-7089, 1619-7070print), 2015; 42: S416-S416.
Impact Factor: 5.537
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Formicola F, Riccardi A, Vigliar E, Biondi B, Accurso A, Del Vecchio W, Imbriaco M
* Multimetastatic medullary thyroid carcinoma to the breast: PET/CT--mammographic-US and MR findings (665 views)
Breast J (ISSN: 1075-122x), 2014 Nov; 20(6): 653-654.
Impact Factor: 1.411
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Gallicchio R, Giacomobono S, Nardelli A, Pellegrino T, Simeon V, Gattozzi D, Maddalena F, Mainenti PP, Storto G
* Palliative Treatment Of Bone Metastases With Samarium-153 Edtmp At Onset Of Pain (876 views)
J Bone Miner Metab (ISSN: 0914-8779), 2014 Jul; 32(4): 434-440.
Impact Factor: 2.46
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Fonti R, Mainolfi C, Anzivino A, Camera L, Faggiano A, Colao A, Salvatore M, Del Vecchio S
* 18F-FDG-PET/CT and 111In-Octreotide SPECT in Patients with Metastatic Medullary Thyroid Carcinoma (590 views)
Eur J Nucl Med (ISSN: 1619-7070, 1619-7089, 0340-6997), 2013 Oct; 40: N/D-N/D.
Impact Factor: 5.217
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D'Antuono F, Nardelli A, Gallicchio R, Giacomobono S, Venetucci A, Pellegrino T, Leggiadro F, D'Errico N, Gattozzi D, Mainenti PP, Storto G
* Palliative Treatment of Bone Metastases with Sm-153 EDTMP at Pain Onset (492 views)
Eur J Nucl Med (ISSN: 1619-7070, 1619-7089, 0340-6997), 2013 Oct; 40: N/D-N/D.
Impact Factor: 5.217
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Gallicchio R, Giacomobono S, Capacchione D, Nardelli A, Barbato F, Nappi A, Pellegrino T, Storto G
* Should patients with remnants from thyroid microcarcinoma really not be treated with iodine-131 ablation? (769 views)
Endocrine (ISSN: 1355-008x, 1355-008xlinking), 2013 Oct; 44(2): 426-433.
Impact Factor: 3.527
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Passaro C, Abagnale A, Libertini S, Volpe M, Botta G, Cella L, Pacelli R, Halldèn G, Gillespie D, Portella G
* Ionizing radiation enhances dl922-947-mediated cell death of anaplastic thyroid carcinoma cells (912 views)
Endocr Relat Cancerendocrine Related Cancer (ISSN: 1351-0088), 2013 Sep 19; 20(5): 633-647.
Impact Factor: 4.907
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Storto G, Gallicchio R, Pellegrino T, Nardelli A, Capacchione D, Sirignano C, Pace L
* Impact of F-18-fluoride PET-CT on implementing early treatment of painful bone metastases with Sm-153 EDTMP (678 views) (PDF 70 views)
Nucl Med Biol (ISSN: 0969-8051, 0883-2897, 0969-8051linking), 2013 May; 40(4): 518-523.
Impact Factor: 2.408
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Marotta V, Ramundo V, Camera L, Del Prete M, Fonti R, Esposito R, Palmieri G, Salvatore M, Vitale M, Colao A, Faggiano A
* Sorafenib in advanced iodine-refractory differentiated thyroid cancer: Efficacy, safety and exploratory analysis of role of serum thyroglobulin and FDG-PET (758 views)
Clin Endocrinol (ISSN: 0300-0664, 1365-2265, 1365-2265electronic), 2013 May; 78(5): 760-767.
Impact Factor: 3.353
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D'Angelo D, Borbone E, Palmieri D, Uboldi S, Esposito F, Frapolli R, Pacelli R, D'Incalci M, Fusco A
* The impairment of the High Mobility Group A (HMGA) protein function contributes to the anticancer activity of trabectedin (614 views)
European Journal Of Cancer (ISSN: 0959-8049), 2013 Mar; 49(5): 1142-1151.
Impact Factor: 4.819
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Bombardieri E, Ambrosini V, Aktolun C, Baum RP, Bishof-delaloye A, Del Vecchio S, Maffioli L, Mortelmans L, Oyen W, Pepe G, Chiti A
* In-111-pentetreotide scintigraphy: procedure guidelines for tumour imaging (887 views)
Eur J Nucl Med (ISSN: 1619-7070, 1619-7089, 0340-6997), 2010 Jul; 37(7): 1441-1448.
Impact Factor: 5.036
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Caleo O, Maurea S, Klain M, Salvatore B, Storto G, Mancini M, Pace L, Salvatore M
* Postsurgical diagnostic evaluation of patients with differentiated thyroid carcinoma: Comparison of ultrasound, iodine-131 scintigraphy and PET with fluorine-18 fluorodeoxyglucose (482 views)
Radiol Med (ISSN: 0033-8362, 1826-6983, 1826-6983electronic), 2009 Dec; 114(8): 1385-1385.
Impact Factor: 1.454
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Pace L, Nicolai E, Klain M, Salvatore M
* Diagnostic value of FDG PET/CT imaging (680 views)
Q J Nucl Med Mol Im (ISSN: 1824-4785, 1824-4478, 1824-4785linking), 2009; 53(5): 503-512.
Impact Factor: 1.724
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Storto G, Pellegrino T, Nardelli A, De Falco T, Castaldi E, Ortosecco G, Capasso E, Erra P, Speranza A, Klain M, Molino L, Di Nuzzo C, Pace L, Salvatore M
* Impact of PET-CT with F-18 Fluoride in Implementing Treatment of Painful Bone Metastases with Sm-153 EDTMP (497 views)
Eur J Nucl Med (ISSN: 1619-7070, 1619-7089, 0340-6997), 2008 Oct; 35: N/D-N/D.
Impact Factor: 4.532
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Salvatore B, Paone G, Klain M, Storto G, Nicolai E, D'Amico D, Della Morte AM, Pace L, Salvatore M
* Fluorodeoxyglucose PET/CT in patients with differentiated thyroid cancer and elevated thyroglobulin after total thyroidectomy and 131I ablation (1015 views)
Q J Nucl Med Mol Im (ISSN: 1824-4785, 1824-4478, 1824-4785linking), 2008 Mar; 52(1): 2-8.
Impact Factor: 1.724
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Caleo O, Maurea S, Klain M, Salvatore B, Storto G, Mancini M, Pace L, Salvatore M
* Postsurgical diagnostic evaluation of patients with differentiated thyroid carcinoma: Comparison of ultrasound, iodine-131 scintigraphy and PET with fluorine-18 fluorodeoxyglucose (747 views)
Radiol Med (ISSN: 0033-8362, 1826-6983, 1826-6983electronic), 2008 Mar; 113(2): 278-288.
Impact Factor: 0.955
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Storto G, Klain M, Paone G, Liuzzi R, Molino L, Marinelli A, Soricelli A, Pace L, Salvatore M
* Combined therapy of Sr-89 and zoledronic acid in patients with painful bone metastases (683 views)
Bone (ISSN: 8756-3282), 2006 Jul; 39(1): 35-41.
Impact Factor: 3.829
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Iommelli F, Zannetti A, Pepe S, Sabbatino F, Laus G, Ghidelli L, Solla R, Scala S, Del Vecchio S, Salvatore M, Pacelli R
* Inhibition of NF-kappa B activity potentiates ionizing radiation and cisplatin induced cell killing of anaplastic thyroid carcinoma cells (792 views)
Meetingproceedings Of The American Association For Cancer Research Annual (ISSN: 0197-016x), 2006 Apr; 47: N/D-N/D.
Impact Factor: 0
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Pace L, Klain M, Albanese C, Salvatore B, Storto G, Soricelli A, Salvatore M
* Short-term outcome of differentiated thyroid cancer patients receiving a second iodine-131 therapy on the basis of a detectable serum thyroglobulin level after initial treatment (602 views)
Eur J Nucl Med (ISSN: 1619-7070, 1619-7089, 0340-6997), 2006 Feb; 33(2): 179-183.
Impact Factor: 4.041
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Storto G, Paone G, Klain M, Salvatore B, Capacchione D, Soricelli A, Pace L, Salvatore M
* Hematological Toxicity in Patients with Painful Bone Metastases Treated with Sr-89 and Zoledronic Acid (417 views)
Eur J Nucl Med (ISSN: 1619-7070, 1619-7089, 0340-6997), 2005 Sep; 32: N/D-N/D.
Impact Factor: 3.883
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Pace L, Klain M, Soricelli A, Albanese C, Salvatore B, Storto G, Salvatore M
* Short Term Outcome of Differentiated Thyroid Cancer Patients with Detectable Serum Thyroglobulin after Initial Treatment Receiving a Second 131-IODINE Therapy (685 views)
Eur J Nucl Med (ISSN: 1619-7070, 1619-7089, 0340-6997), 2005 Sep; 32: 179-183.
Impact Factor: 3.883
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Cozzolino R, Palladino P, Rossi F, Cali G, Benedetti E, Laccetti P
* Antineoplastic cyclic astin analogues kill tumour cells via caspase-mediated induction of apoptosis (778 views)
Carcinogenesis (ISSN: 0143-3334), 2005 Apr; 26(4): 733-739.
Impact Factor: 5.108
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Tauchmanovà L, Pensabene M, Capuano I, Spagnoletti I, Zeppa P, Del Vecchio S, Mainenti PP, De Rosa G, Colao A, Contegiacomo A
* Poorly differentiated small cell neuroendocrine carcinoma localized in three different endocrine glands: Response to chemotherapy and octreotide LAR (579 views)
J Endocrinol Invest (ISSN: 0391-4097, 1720-8386electronic), 2005 Apr; 28(4): 371-378.
Impact Factor: 1.496
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Storto G, Paone G, Ibello F, Klain M, Liuzzi R, Marinelli A, Soricelli A, Pace L, Salvatore M
* Combined therapy of Sr-89 and zoledronic acid in patients with painful bone metastases (569 views)
Eur J Nucl Med (ISSN: 1619-7070, 1619-7089, 0340-6997), 2004 Sep; 31: N/D-N/D.
Impact Factor: 3.935
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Portella G, Pacelli R, Libertini S, Cella L, Vecchio G, Salvatore M, Fusco A
* ONYX-015 Enhances Radiation-Induced Death of Human Anaplastic Thyroid Carcinoma Cells (829 views)
J Clin Endocrinol Metab Journal Of Clinical Endocrinology And Metabolism (ISSN: 0021-972x), 2003 Oct 1; 88(10): 5027-5032.
Impact Factor: 5.873
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Spalletti-cernia D, Sorrentino R, Di Gaetano S, Arciello A, Garbi C, Piccoli R, D'Alessio G, Vecchio G, Laccetti P, Santoro M
* Antineoplastic ribonucleases selectively kill thyroid carcinoma cells via caspase-mediated induction of apoptosis (703 views)
Journal Of Clinical Endocrinology & Metabolism (ISSN: 0021-972x), 2003 Jun; 88(6): 2900-2907.
Impact Factor: 5.873
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Kim KM, Varrone A, Watabe H, Shidahara M, Fujita M, Innis RB, Iida H
* Contribution of scatter and attenuation compensation to SPECT images of nonuniformly distributed brain activities (552 views)
J Nucl Med (ISSN: 0161-5505, 1535-5667, 1535-5667electronic), 2003 Apr; 44(4): 512-519.
Impact Factor: 4.899
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Colao A, Lastoria S, Ferone D, Varrella P, Marzullo P, Pivonello R, Cerbone G, Acampa W, Salvatore M, Lombardi G
The pituitary uptake of In-111-DTPA-D-Phe(1)-octreotide in the normal pituitary and in pituitary adenomas (672 views)
J Endocrinol Invest (ISSN: 0391-4097, 1720-8386electronic), 1999 Mar; 22(3): 176-183.
Impact Factor: 0.957
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Fonti R, Cheung N-KV, Bridger GJ, Guo H-F, Abrams MJ, Larson SM
99mTc-monoclonal antibody radiolabeled via hydrazino nicotinamide derivative for imaging disialoganglioside G(D2)-positive tumors (831 views)
Nucl Med Biol (ISSN: 0969-8051, 0883-2897), 1999; 26(6): 681-686.
Impact Factor: 1.623
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Ferone D, Lastoria S, Colao A, Varrella P, Cerbone G, Acampa W, Merola B, Salvatore M, Lombardi G
Correlation of scintigraphic results using 123I-methoxybenzamide with hormone levels and tumor size response to quinagolide in patients with pituitary adenomas (731 views)
J Clin Endocrinol Metab (ISSN: 0021-972x), 1998 Jan; 83(1): 248-252.
Impact Factor: 5.641
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Postiglione A, Soricelli, Salvatore M, Lassen NA
123I-iomazenil as a clinical tool for studying neuronal loss [4] (695 views)
J Am Geriatr Soc (ISSN: 0002-8614), 1997 Apr; 45(4): 534-536.
Impact Factor: 2.806
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Biondi B, Fazio S, Cuocolo A, Sabatini D, Nicolai E, Lombardi G, Salvatore M, Sacca L
Impaired cardiac reserve and exercise capacity in patients receiving long-term thyrotropin suppressive therapy with levothyroxine (600 views)
J Clin Endocrinol Metab (ISSN: 0021-972x), 1996 Dec; 81(12): 4224-4228.
Impact Factor: 4.575
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Li PY, Del Vecchio S, Fonti R, Carriero MV, Potena MI, Botti G, Miotti S, Lastoria S, Menard S, Colnaghi MI, Salvatore M
Local concentration of folate binding protein GP38 in sections of human ovarian carcinoma by in vitro quantitative autoradiography (736 views)
J Nucl Med (ISSN: 0161-5505, 1535-5667, 1535-5667electronic), 1996 Apr; 37(4-6): 665-672.
Impact Factor: 3.491
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Lastoria S, Maurea S, Vergara E, Acampa W, Varrella P, Klain M, Muto P, Bernardy JD, Salvatore M
Comparison of labeled MIBG and somatostatin analogs in imaging neuroendocrine tumors (648 views)
Q J Nucl Med (ISSN: 1125-0135, 1124-3937), 1995 Dec; 39(4Suppl1): 145-149.
Impact Factor: 2.125
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Maurea S, Cuocolo A, Reynolds J, Keiser H, Neumann R, Salvatore M
Iodine-131 metaiodobenzylguanidine scintigraphy in the evaluation of paragangliomas. Comparison between benign and malignant tumors (604 views)
Radiol Med (ISSN: 0033-8362, 1826-6983, 1826-6983electronic), 1994; 87(5): 688-693.
Impact Factor: 0.967
View Export to BibTeX Export to EndNote
Maurea S, Maurelli L, Lastoria S, Cuocolo A, Brunetti A, Pace L, Caracò C, Klain M, Lupoli G, Salvatore M
Familial pheochromocytoma in Sipple's syndrome. A comparison between scintigraphy with 131I-meta-iodobenzylguanidine, computed tomography and echography (516 views)
Radiol Med (ISSN: 0033-8362, 1826-6983, 1826-6983electronic), 1992; 83(4): 486-490.
Impact Factor: 0.967
View Export to BibTeX Export to EndNote
Maurelli L, Cuocolo A, Lastoria S, Brunetti A, Maurea S, Lembo G, Klain M, Carac C, Salvatore M
131I-meta-iodobenzylguanidine scintigraphy in patients with a suspected pheochromocytoma. A comparison with CT and biohumoral parameters (1270 views)
Radiol Med (ISSN: 0033-8362, 1826-6983, 1826-6983electronic), 1991; 82(6): 839-843.
Impact Factor: 0.967
View Export to BibTeX Export to EndNote
Marchetti P, Benzi L, Trischitta V, Brunetti A, Cecchetti P, Ciccarone AM, Pezzino V, Vigneri R, Navalesi R
Complementary use of gel permeation and reversed-phase liquid chromatography for the analysis of A14-[125I]insulin and its degradation products in isolated human monocytes (2025 views)
J Chromatogr B Biomed Sci Appl (ISSN: 0378-4347), 1986 Apr 25; 377(C): 339-344.
Impact Factor: 1.588
View Export to BibTeX Export to EndNote
43 Records (35 excluding Abstracts).
Total impact factor: 138.04 (111.394 excluding Abstracts).
Total 5 year impact factor: 134.992 (107.527 excluding Abstracts).
Total impact factor: 138.04 (111.394 excluding Abstracts).
Total 5 year impact factor: 134.992 (107.527 excluding Abstracts).
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