NIR Emitting Nanoprobes Based on Cyclic RGD Motif Conjugated PbS Quantum Dots for Integrin-Targeted Optical Bioimaging (416 views) (PDF public 184 views)
Acs Appl Mater Inter (ISSN: 1944-8244), 2017 Dec 13; 9(49): 43113-43126.
Export to BibTeX Export to EndNote
Paper type: Journal Article,
Impact factor: 8.097, 5-year impact factor: 8.284
Url: https://www.scopus.com/inward/record.uri?eid=2-s2.0-85038208885&doi=10.1021%2facsami.7b14155&partnerID=40&md5=d75bf560fca161cb4640e6a8bc3ff9bd
Keywords: Nir Emitting Quantum Dots, Cyclic Rgd Peptide, Silica-Coated Nanoprobes, Targeted Imaging, Alphavbeta3 Integrin Receptor, αvβ3 Integrin Receptor, Amino Acids, Infrared Devices, Lead Compounds, Microemulsions, Nanocrystals, Nanostructures, Semiconducting Lead Compounds, Solutions, Tumors, Arginine-Glycine-Aspartic Acids, Luminescent Nanostructures, Photoluminescence Emission, Silica Coated, Water-In-Oil Microemulsions, Semiconductor Quantum Dots,
Affiliations:
*** IBB - CNR ***
Istituto per i Processi Chimico-Fisici-CNR SS Bari , Via Orabona 4, 70125 Bari, Italy., Istituto di Biostrutture e Bioimmagini-CNR , Via Mezzocannone 16, 80134 Napoli, Italy., Istituto Tumori IRCCS Giovanni Paolo II , Viale Orazio Flacco 65, 70124 Bari, Italy., Istituto di Cristallografia-CNR Bari , Via Amendola 122/O, 70126 Bari, Italy.,
Dipartimento di Chimica, Università degli Studi di Bari Aldo Moro, Via Orabona 4, Bari, 70125, Italy
Dipartimento di Farmacia-Scienze Del Farmaco, Università degli Studi di Bari Aldo Moro, Via Orabona 4, Bari, 70125, Italy
Electron Microscopy Facility, Istituto Italiano di Tecnologia (IIT), via Morego 30, Genova, Italy
References:
Zhang, L., Bhatnagar, S., Deschenes, E., Thurber, G.M., Mechanistic and quantitative insight into cell surface targeted molecular imaging agent design (2016) Sci. Rep., 6, p. 2542
Sun, X., Li, Y., Liu, T., Li, Z., Zhang, X., Chen, X., Peptide-based imaging agents for cancer detection (2017) Adv. Drug Delivery Rev., 110-111, pp. 38-51
Juhl, K., Christensen, A., Persson, M., Ploug, M., Kjaer, A., Peptide-Based Optical uPAR Imaging for Surgery: In Vivo Testing of ICG-Glu-Glu-AE105 (2016) PLoS One, 11, p. e0147428
Fernández, A., Vendrell, M., Smart fluorescent probes for imaging macrophage activity (2016) Chem. Soc. Rev., 45, pp. 1182-1196
Reubi, J.C., Maecke, H.R., Peptide-based probes for cancer imaging (2008) J. Nucl. Med., 49, pp. 1735-1738
Okarvi, S.M., Peptide-based radiopharmaceuticals: Future tools for diagnostic imaging of cancers and other diseases (2004) Med. Res. Rev., 24, pp. 357-397
Stoykow, C., Erbes, T., Maecke, H.R., Bulla, S., Bartholomä, M., Mayer, S., Drendel, V., Meyer, P.T., Gastrin-releasing Peptide Receptor Imaging in Breast Cancer Using the Receptor Antagonist 68Ga-RM2 and PET (2016) Theranostics, 6, pp. 1641-1650
Morgat, C., Mishra, A.K., Varshney, R., Allard, M., Fernandez, P., Hindié, E., Targeting Neuropeptide Receptors for Cancer Imaging and Therapy: Perspectives with Bombesin, Neurotensin, and Neuropeptide-Y Receptors (2014) J. Nucl. Med., 55, pp. 1650-1657
Tang, B., Yong, X., Xie, R., Li, Q.-W., Yang, S.-M., Vasoactive intestinal peptide receptor-based imaging and treatment of tumors (2014) Int. J. Oncol., 44, pp. 1023-1031
Cai, W., Niu, G., Chen, X., Imaging of integrins as biomarkers for tumor angiogenesis (2008) Curr. Pharm. Des., 14, pp. 2943-2973
Reubi, J.C., Targeting CCK receptors in human cancers (2007) Curr. Top. Med. Chem., 7, pp. 1239-1242
Körner, M., Stockli, M., Waser, B., Reubi, J.C., GLP-1 receptor expression in human tumors and human normal tissues: Potential for in vivo targeting (2007) J. Nucl. Med., 48, pp. 736-743
Miao, Y., Quinn, T.P., Alpha-melanocyte stimulating hormone peptide-targeted melanoma imaging (2007) Front Biosci., 12, pp. 4514-4524
Deutscher, S.L., Phage display in molecular imaging and diagnosis of cancer (2010) Chem. Rev., 110, pp. 3196-3211
Li, Z.J., Cho, C.H., Development of peptides as potential drugs for cancer therapy (2010) Curr. Pharm. Des., 16, pp. 1180-1189
Lee, S., Xie, J., Chen, X., Peptide-based probes for targeted molecular imaging (2010) Biochemistry, 49, pp. 1364-1376
Fani, M., Maecke, H.R., Okarvi, S.M., Radiolabeled Peptides: Valuable Tools for the Detection and Treatment of Cancer (2012) Theranostics, 2, pp. 481-501
Zhu, D., Qin, Y., Wang, J., Zhang, L., Zou, S., Zhu, X., Zhu, L., Novel Glypican-3-Binding Peptide for in Vivo Hepatocellular Carcinoma Fluorescent Imaging (2016) Bioconjugate Chem., 27, pp. 831-839
Maschauer, S., Einsiedel, J., Hübner, H., Gmeiner, P., Prante, O., (18)F- and (68)Ga-Labeled Neurotensin Peptides for PET Imaging of Neurotensin Receptor 1 (2016) J. Med. Chem., 59, pp. 6480-6492
Li, L., Wu, Y., Wang, Z., Jia, B., Hu, Z., Dong, C., Wang, F., SPECT/CT Imaging of the Novel HER2-Targeted Peptide Probe 99mTc-HYNIC-H6F in Breast Cancer Mouse Models (2017) J. Nucl. Med., 58, pp. 821-826
Preslar, A.T., Tantakitti, F., Park, K., Zhang, S., Stupp, S.I., Meade, T.J., 19F Magnetic Resonance Imaging Signals from Peptide Amphiphile Nanostructures Are Strongly Affected by Their Shape (2016) ACS Nano, 10, pp. 7376-7384
Valente, G., Depalo, N., De Paola, I., Iacobazzi, R.M., Denora, N., Laquintana, V., Comparelli, R., Curri, M.L., Integrin-targeting with peptide-bioconjugated semiconductor-magnetic nanocrystalline heterostructures (2016) Nano Res., 9, pp. 644-662
Escobedo, J.O., Rusin, O., Lim, S., Strongin, R.M., NIR dyes for bioimaging applications (2010) Curr. Opin. Chem. Biol., 14, pp. 64-70
Bouccara, S., Sitbon, G., Fragola, A., Loriette, V., Lequeux, N., Pons, T., Enhancing fluorescence in vivo imaging using inorganic nanoprobes (2015) Curr. Opin. Biotechnol., 34, pp. 65-72
Depalo, N., De Leo, V., Corricelli, M., Gristina, R., Valente, G., Casamassima, E., Comparelli, R., Curri, M.L., Lipid-based systems loaded with PbS nanocrystals: Near infrared emitting trackable nanovectors (2017) J. Mater. Chem. B, 5, pp. 1471-1481
Corricelli, M., Depalo, N., Di Carlo, E., Fanizza, E., Laquintana, V., Denora, N., Agostiano, A., Curri, M.L., Biotin-decorated silica coated PbS nanocrystals emitting in the second biological near infrared window for bioimaging (2014) Nanoscale, 6, pp. 7924-7933
Kim, D., Lee, N., Park, Y., Hyeon, T., Recent Advances in Inorganic Nanoparticle-Based NIR Luminescence Imaging: Semiconductor Nanoparticles and Lanthanide Nanoparticles (2017) Bioconjugate Chem., 28, pp. 115-123
Fanizza, E., Urso, C., Iacobazzi, R.M., Depalo, N., Corricelli, M., Panniello, A., Agostiano, A., Curri, M.L., Fabrication of Photoactive Heterostructures based on Quantum Dots Decorated with Au Nanoparticles (2016) Sci. Technol. Adv. Mater., 17, pp. 98-108
Fanizza, E., Iacobazzi, R.M., Laquintana, V., Valente, G., Caliandro, G., Striccoli, M., Agostiano, A., Denora, N., Highly selective luminescent nanostructures for mitochondrial imaging and targeting (2016) Nanoscale, 8, pp. 3350-3361
Bilan, R., Fleury, F., Nabiev, I., Sukhanova, A., Quantum Dot Surface Chemistry and Functionalization for Cell Targeting and Imaging (2015) Bioconjugate Chem., 26, pp. 609-624
Wang, L.W., Peng, C.W., Chen, C., Li, Y., Quantum dots-based tissue and in vivo imaging in breast cancer researches: Current status and future perspectives (2015) Breast Cancer Res. Treat., 151, pp. 7-17
Alibolandi, M., Abnous, K., Sadeghi, F., Hosseinkhani, H., Ramezani, M., Hadizadeh, F., Folate receptor-targeted multimodal polymersomes for delivery of quantum dots and doxorubicin to breast adenocarcinoma: In vitro and in vivo evaluation (2016) Int. J. Pharm., 500, pp. 162-178
Latronico, T., Depalo, N., Valente, G., Fanizza, E., Laquintana, V., Denora, N., Fasano, A., Liuzzi, G.M., Cytotoxicity Study on Luminescent Nanocrystals Containing Phospholipid Micelles in Primary Cultures of Rat Astrocytes (2016) PLoS One, 11, p. e0153451
Bilan, R., Nabiev, I., Sukhanova, A., Quantum Dot-Based Nanotools for Bioimaging, Diagnostics, and Drug Delivery (2016) ChemBioChem, 17, pp. 2103-2114
Cai, W., Chen, X., Nanoplatforms for targeted molecular imaging in living subjects (2007) Small, 3, pp. 1840-1854
Smith, A.M., Duan, H., Mohs, A.M., Nie, S., Bioconjugated quantum dots for in vivo molecular and cellular imaging (2008) Adv. Drug Delivery Rev., 60, pp. 1226-1240
Wang, Z., Chui, W.K., Ho, P.C., Integrin targeted drug and gene delivery (2010) Expert Opin. Drug Delivery, 7, pp. 159-171
Zhang, Y., Yang, Y., Cai, W., Multimodality Imaging of Integrin αvβ3 Expression (2011) Theranostics, 1, pp. 135-148
Choi, N., Kim, S.-M., Hong, K.S., Cho, G., Cho, J.-H., Lee, C., Ryu, E.K., The use of the fusion protein RGD-HSA-TIMP2 as a tumor targeting imaging probe for SPECT and PET (2011) Biomaterials, 32, pp. 7151-7158
Danhier, F., Le Breton, A., Préat, V., RGD-Based Strategies to Target Alpha(v) Beta(3) Integrin in Cancer Therapy and Diagnosis (2012) Mol. Pharmaceutics, 9, pp. 2961-2973
Ma, Y., Ai, G., Zhang, C., Zhao, M., Dong, X., Han, Z., Wang, Z., Gu, Y., Novel Linear Peptides with High Affinity to αvβ3 Integrin for Precise Tumor Identification (2017) Theranostics, 7, pp. 1511-1523
Zannetti, A., Del Vecchio, S., Iommelli, F., Del Gatto, A., De Luca, S., Zaccaro, L., Papaccioli, A., Salvatore, M., Imaging ofαvβ3Expression by a Bifunctional Chimeric RGD Peptidenot Cross-Reacting withαvβ5 (2009) Clin. Cancer Res., 15, pp. 5224-5233
Arosio, D., Manzoni, L., Araldi, E.M.V., Scolastico, C., Cyclic RGD Functionalized Gold Nanoparticles for Tumor Targeting (2011) Bioconjugate Chem., 22, pp. 664-672
Farina, B., De Paola, I., Russo, L., Capasso, D., Liguoro, A., Del Gatto, A., Saviano, M., Fattorusso, R., A Combined NMR and Computational Approach to Determine the RGDechi-hCit-α v β 3 Integrin Recognition Mode in Isolated Cell Membranes (2016) Chem. - Eur. J., 22, pp. 681-693
Corricelli, M., Enrichi, F., Altamura, D., De Caro, L., Giannini, C., Falqui, A., Agostiano, A., Striccoli, M., Near infrared emission from monomodal and bimodal PbS nanocrystal superlattices (2012) J. Phys. Chem. C, 116, pp. 6143-6152
Fanizza, E., Depalo, N., Clary, L., Agostiano, A., Striccoli, M., Curri, M.L., A combined size sorting strategy for monodisperse plasmonic nanostructures (2013) Nanoscale, 5, pp. 3272-3282
Depalo, N., Iacobazzi, R.M., Valente, G., Arduino, I., Villa, S., Canepa, F., Laquintana, V., Denora, N., Sorafenib delivery nanoplatform based on superparamagnetic iron oxide nanoparticles magnetically targets hepatocellular carcinoma (2017) Nano Res., 10, pp. 2431-2448
Scarì, G., Porta, F., Fascio, U., Avvakumova, S., Dal Santo, V., De Simone, M., Saviano, M., Zaccaro, L., Gold Nanoparticles Capped by a GC-Containing Peptide Functionalized with an RGD Motif for Integrin Targeting (2012) Bioconjugate Chem., 23, pp. 340-349
Krpetić, Z., Nativo, P., Porta, F., Brust, M., A multidentate peptide for stabilization and facile bioconjugation of gold nanoparticles (2009) Bioconjugate Chem., 20, pp. 619-624
Porta, F., Speranza, G., Krpetić, Ž., Dal Santo, V., Francescato, P., Scarì, G., Gold nanoparticles capped by peptides (2007) Mater. Sci. Eng., B, 140, pp. 187-194
Shuhendler, A.J., Prasad, P., Leung, M., Rauth, A.M., Da Costa, R.S., Wu, X.Y., A Novel Solid Lipid Nanoparticle Formulation for Active Targeting to Tumor αvβ3 Integrin Receptors Reveals Cyclic RGD as A Double-Edged Sword (2012) Adv. Healthcare Mater., 1, pp. 600-608
Gentilcore, G., Madonna, G., Mozzillo, N., Ribas, A., Cossu, A., Palmieri, G., Ascierto, P.A., Effect of dabrafenib on melanoma cell lines harbouring the BRAF V600D/R mutations (2013) BMC Cancer, 13, p. 17
Capasso, D., De Paola, I., Liguoro, A., Del Gatto, A., Di Gaetano, S., Guarnieri, D., Saviano, M., Zaccaro, L., RGDechi-hCit: αvβ3 selective pro-apoptotic peptide as potential carrier for drug delivery into melanoma metastatic cells (2014) PLoS One, 9, p. e106441
Lim, E.H., Danthi, N., Bednarski, M., Li, K.C.P., A review: Integrin αvβ3-targeted molecular imaging and therapy in angiogenesis (2005) Nanomed.: Nanotechnol., Biol., Med., 1, pp. 110-114
Jia, Z., Song, L., Zang, F., Song, J., Zhang, W., Yan, C., Xie, J., Zhang, Y., Active-target T1-weighted MR Imaging of Tiny Hepatic Tumor via RGD Modified Ultra-small Fe3O4 Nanoprobes (2016) Theranostics, 6, pp. 1780-1791
Acs Appl Mater Inter (ISSN: 1944-8244), 2017 Dec 13; 9(49): 43113-43126.
Export to BibTeX Export to EndNote
Paper type: Journal Article,
Impact factor: 8.097, 5-year impact factor: 8.284
Url: https://www.scopus.com/inward/record.uri?eid=2-s2.0-85038208885&doi=10.1021%2facsami.7b14155&partnerID=40&md5=d75bf560fca161cb4640e6a8bc3ff9bd
Keywords: Nir Emitting Quantum Dots, Cyclic Rgd Peptide, Silica-Coated Nanoprobes, Targeted Imaging, Alphavbeta3 Integrin Receptor, αvβ3 Integrin Receptor, Amino Acids, Infrared Devices, Lead Compounds, Microemulsions, Nanocrystals, Nanostructures, Semiconducting Lead Compounds, Solutions, Tumors, Arginine-Glycine-Aspartic Acids, Luminescent Nanostructures, Photoluminescence Emission, Silica Coated, Water-In-Oil Microemulsions, Semiconductor Quantum Dots,
Affiliations:
*** IBB - CNR ***
Istituto per i Processi Chimico-Fisici-CNR SS Bari , Via Orabona 4, 70125 Bari, Italy., Istituto di Biostrutture e Bioimmagini-CNR , Via Mezzocannone 16, 80134 Napoli, Italy., Istituto Tumori IRCCS Giovanni Paolo II , Viale Orazio Flacco 65, 70124 Bari, Italy., Istituto di Cristallografia-CNR Bari , Via Amendola 122/O, 70126 Bari, Italy.,
Dipartimento di Chimica, Università degli Studi di Bari Aldo Moro, Via Orabona 4, Bari, 70125, Italy
Dipartimento di Farmacia-Scienze Del Farmaco, Università degli Studi di Bari Aldo Moro, Via Orabona 4, Bari, 70125, Italy
Electron Microscopy Facility, Istituto Italiano di Tecnologia (IIT), via Morego 30, Genova, Italy
References:
Zhang, L., Bhatnagar, S., Deschenes, E., Thurber, G.M., Mechanistic and quantitative insight into cell surface targeted molecular imaging agent design (2016) Sci. Rep., 6, p. 2542
Sun, X., Li, Y., Liu, T., Li, Z., Zhang, X., Chen, X., Peptide-based imaging agents for cancer detection (2017) Adv. Drug Delivery Rev., 110-111, pp. 38-51
Juhl, K., Christensen, A., Persson, M., Ploug, M., Kjaer, A., Peptide-Based Optical uPAR Imaging for Surgery: In Vivo Testing of ICG-Glu-Glu-AE105 (2016) PLoS One, 11, p. e0147428
Fernández, A., Vendrell, M., Smart fluorescent probes for imaging macrophage activity (2016) Chem. Soc. Rev., 45, pp. 1182-1196
Reubi, J.C., Maecke, H.R., Peptide-based probes for cancer imaging (2008) J. Nucl. Med., 49, pp. 1735-1738
Okarvi, S.M., Peptide-based radiopharmaceuticals: Future tools for diagnostic imaging of cancers and other diseases (2004) Med. Res. Rev., 24, pp. 357-397
Stoykow, C., Erbes, T., Maecke, H.R., Bulla, S., Bartholomä, M., Mayer, S., Drendel, V., Meyer, P.T., Gastrin-releasing Peptide Receptor Imaging in Breast Cancer Using the Receptor Antagonist 68Ga-RM2 and PET (2016) Theranostics, 6, pp. 1641-1650
Morgat, C., Mishra, A.K., Varshney, R., Allard, M., Fernandez, P., Hindié, E., Targeting Neuropeptide Receptors for Cancer Imaging and Therapy: Perspectives with Bombesin, Neurotensin, and Neuropeptide-Y Receptors (2014) J. Nucl. Med., 55, pp. 1650-1657
Tang, B., Yong, X., Xie, R., Li, Q.-W., Yang, S.-M., Vasoactive intestinal peptide receptor-based imaging and treatment of tumors (2014) Int. J. Oncol., 44, pp. 1023-1031
Cai, W., Niu, G., Chen, X., Imaging of integrins as biomarkers for tumor angiogenesis (2008) Curr. Pharm. Des., 14, pp. 2943-2973
Reubi, J.C., Targeting CCK receptors in human cancers (2007) Curr. Top. Med. Chem., 7, pp. 1239-1242
Körner, M., Stockli, M., Waser, B., Reubi, J.C., GLP-1 receptor expression in human tumors and human normal tissues: Potential for in vivo targeting (2007) J. Nucl. Med., 48, pp. 736-743
Miao, Y., Quinn, T.P., Alpha-melanocyte stimulating hormone peptide-targeted melanoma imaging (2007) Front Biosci., 12, pp. 4514-4524
Deutscher, S.L., Phage display in molecular imaging and diagnosis of cancer (2010) Chem. Rev., 110, pp. 3196-3211
Li, Z.J., Cho, C.H., Development of peptides as potential drugs for cancer therapy (2010) Curr. Pharm. Des., 16, pp. 1180-1189
Lee, S., Xie, J., Chen, X., Peptide-based probes for targeted molecular imaging (2010) Biochemistry, 49, pp. 1364-1376
Fani, M., Maecke, H.R., Okarvi, S.M., Radiolabeled Peptides: Valuable Tools for the Detection and Treatment of Cancer (2012) Theranostics, 2, pp. 481-501
Zhu, D., Qin, Y., Wang, J., Zhang, L., Zou, S., Zhu, X., Zhu, L., Novel Glypican-3-Binding Peptide for in Vivo Hepatocellular Carcinoma Fluorescent Imaging (2016) Bioconjugate Chem., 27, pp. 831-839
Maschauer, S., Einsiedel, J., Hübner, H., Gmeiner, P., Prante, O., (18)F- and (68)Ga-Labeled Neurotensin Peptides for PET Imaging of Neurotensin Receptor 1 (2016) J. Med. Chem., 59, pp. 6480-6492
Li, L., Wu, Y., Wang, Z., Jia, B., Hu, Z., Dong, C., Wang, F., SPECT/CT Imaging of the Novel HER2-Targeted Peptide Probe 99mTc-HYNIC-H6F in Breast Cancer Mouse Models (2017) J. Nucl. Med., 58, pp. 821-826
Preslar, A.T., Tantakitti, F., Park, K., Zhang, S., Stupp, S.I., Meade, T.J., 19F Magnetic Resonance Imaging Signals from Peptide Amphiphile Nanostructures Are Strongly Affected by Their Shape (2016) ACS Nano, 10, pp. 7376-7384
Valente, G., Depalo, N., De Paola, I., Iacobazzi, R.M., Denora, N., Laquintana, V., Comparelli, R., Curri, M.L., Integrin-targeting with peptide-bioconjugated semiconductor-magnetic nanocrystalline heterostructures (2016) Nano Res., 9, pp. 644-662
Escobedo, J.O., Rusin, O., Lim, S., Strongin, R.M., NIR dyes for bioimaging applications (2010) Curr. Opin. Chem. Biol., 14, pp. 64-70
Bouccara, S., Sitbon, G., Fragola, A., Loriette, V., Lequeux, N., Pons, T., Enhancing fluorescence in vivo imaging using inorganic nanoprobes (2015) Curr. Opin. Biotechnol., 34, pp. 65-72
Depalo, N., De Leo, V., Corricelli, M., Gristina, R., Valente, G., Casamassima, E., Comparelli, R., Curri, M.L., Lipid-based systems loaded with PbS nanocrystals: Near infrared emitting trackable nanovectors (2017) J. Mater. Chem. B, 5, pp. 1471-1481
Corricelli, M., Depalo, N., Di Carlo, E., Fanizza, E., Laquintana, V., Denora, N., Agostiano, A., Curri, M.L., Biotin-decorated silica coated PbS nanocrystals emitting in the second biological near infrared window for bioimaging (2014) Nanoscale, 6, pp. 7924-7933
Kim, D., Lee, N., Park, Y., Hyeon, T., Recent Advances in Inorganic Nanoparticle-Based NIR Luminescence Imaging: Semiconductor Nanoparticles and Lanthanide Nanoparticles (2017) Bioconjugate Chem., 28, pp. 115-123
Fanizza, E., Urso, C., Iacobazzi, R.M., Depalo, N., Corricelli, M., Panniello, A., Agostiano, A., Curri, M.L., Fabrication of Photoactive Heterostructures based on Quantum Dots Decorated with Au Nanoparticles (2016) Sci. Technol. Adv. Mater., 17, pp. 98-108
Fanizza, E., Iacobazzi, R.M., Laquintana, V., Valente, G., Caliandro, G., Striccoli, M., Agostiano, A., Denora, N., Highly selective luminescent nanostructures for mitochondrial imaging and targeting (2016) Nanoscale, 8, pp. 3350-3361
Bilan, R., Fleury, F., Nabiev, I., Sukhanova, A., Quantum Dot Surface Chemistry and Functionalization for Cell Targeting and Imaging (2015) Bioconjugate Chem., 26, pp. 609-624
Wang, L.W., Peng, C.W., Chen, C., Li, Y., Quantum dots-based tissue and in vivo imaging in breast cancer researches: Current status and future perspectives (2015) Breast Cancer Res. Treat., 151, pp. 7-17
Alibolandi, M., Abnous, K., Sadeghi, F., Hosseinkhani, H., Ramezani, M., Hadizadeh, F., Folate receptor-targeted multimodal polymersomes for delivery of quantum dots and doxorubicin to breast adenocarcinoma: In vitro and in vivo evaluation (2016) Int. J. Pharm., 500, pp. 162-178
Latronico, T., Depalo, N., Valente, G., Fanizza, E., Laquintana, V., Denora, N., Fasano, A., Liuzzi, G.M., Cytotoxicity Study on Luminescent Nanocrystals Containing Phospholipid Micelles in Primary Cultures of Rat Astrocytes (2016) PLoS One, 11, p. e0153451
Bilan, R., Nabiev, I., Sukhanova, A., Quantum Dot-Based Nanotools for Bioimaging, Diagnostics, and Drug Delivery (2016) ChemBioChem, 17, pp. 2103-2114
Cai, W., Chen, X., Nanoplatforms for targeted molecular imaging in living subjects (2007) Small, 3, pp. 1840-1854
Smith, A.M., Duan, H., Mohs, A.M., Nie, S., Bioconjugated quantum dots for in vivo molecular and cellular imaging (2008) Adv. Drug Delivery Rev., 60, pp. 1226-1240
Wang, Z., Chui, W.K., Ho, P.C., Integrin targeted drug and gene delivery (2010) Expert Opin. Drug Delivery, 7, pp. 159-171
Zhang, Y., Yang, Y., Cai, W., Multimodality Imaging of Integrin αvβ3 Expression (2011) Theranostics, 1, pp. 135-148
Choi, N., Kim, S.-M., Hong, K.S., Cho, G., Cho, J.-H., Lee, C., Ryu, E.K., The use of the fusion protein RGD-HSA-TIMP2 as a tumor targeting imaging probe for SPECT and PET (2011) Biomaterials, 32, pp. 7151-7158
Danhier, F., Le Breton, A., Préat, V., RGD-Based Strategies to Target Alpha(v) Beta(3) Integrin in Cancer Therapy and Diagnosis (2012) Mol. Pharmaceutics, 9, pp. 2961-2973
Ma, Y., Ai, G., Zhang, C., Zhao, M., Dong, X., Han, Z., Wang, Z., Gu, Y., Novel Linear Peptides with High Affinity to αvβ3 Integrin for Precise Tumor Identification (2017) Theranostics, 7, pp. 1511-1523
Zannetti, A., Del Vecchio, S., Iommelli, F., Del Gatto, A., De Luca, S., Zaccaro, L., Papaccioli, A., Salvatore, M., Imaging ofαvβ3Expression by a Bifunctional Chimeric RGD Peptidenot Cross-Reacting withαvβ5 (2009) Clin. Cancer Res., 15, pp. 5224-5233
Arosio, D., Manzoni, L., Araldi, E.M.V., Scolastico, C., Cyclic RGD Functionalized Gold Nanoparticles for Tumor Targeting (2011) Bioconjugate Chem., 22, pp. 664-672
Farina, B., De Paola, I., Russo, L., Capasso, D., Liguoro, A., Del Gatto, A., Saviano, M., Fattorusso, R., A Combined NMR and Computational Approach to Determine the RGDechi-hCit-α v β 3 Integrin Recognition Mode in Isolated Cell Membranes (2016) Chem. - Eur. J., 22, pp. 681-693
Corricelli, M., Enrichi, F., Altamura, D., De Caro, L., Giannini, C., Falqui, A., Agostiano, A., Striccoli, M., Near infrared emission from monomodal and bimodal PbS nanocrystal superlattices (2012) J. Phys. Chem. C, 116, pp. 6143-6152
Fanizza, E., Depalo, N., Clary, L., Agostiano, A., Striccoli, M., Curri, M.L., A combined size sorting strategy for monodisperse plasmonic nanostructures (2013) Nanoscale, 5, pp. 3272-3282
Depalo, N., Iacobazzi, R.M., Valente, G., Arduino, I., Villa, S., Canepa, F., Laquintana, V., Denora, N., Sorafenib delivery nanoplatform based on superparamagnetic iron oxide nanoparticles magnetically targets hepatocellular carcinoma (2017) Nano Res., 10, pp. 2431-2448
Scarì, G., Porta, F., Fascio, U., Avvakumova, S., Dal Santo, V., De Simone, M., Saviano, M., Zaccaro, L., Gold Nanoparticles Capped by a GC-Containing Peptide Functionalized with an RGD Motif for Integrin Targeting (2012) Bioconjugate Chem., 23, pp. 340-349
Krpetić, Z., Nativo, P., Porta, F., Brust, M., A multidentate peptide for stabilization and facile bioconjugation of gold nanoparticles (2009) Bioconjugate Chem., 20, pp. 619-624
Porta, F., Speranza, G., Krpetić, Ž., Dal Santo, V., Francescato, P., Scarì, G., Gold nanoparticles capped by peptides (2007) Mater. Sci. Eng., B, 140, pp. 187-194
Shuhendler, A.J., Prasad, P., Leung, M., Rauth, A.M., Da Costa, R.S., Wu, X.Y., A Novel Solid Lipid Nanoparticle Formulation for Active Targeting to Tumor αvβ3 Integrin Receptors Reveals Cyclic RGD as A Double-Edged Sword (2012) Adv. Healthcare Mater., 1, pp. 600-608
Gentilcore, G., Madonna, G., Mozzillo, N., Ribas, A., Cossu, A., Palmieri, G., Ascierto, P.A., Effect of dabrafenib on melanoma cell lines harbouring the BRAF V600D/R mutations (2013) BMC Cancer, 13, p. 17
Capasso, D., De Paola, I., Liguoro, A., Del Gatto, A., Di Gaetano, S., Guarnieri, D., Saviano, M., Zaccaro, L., RGDechi-hCit: αvβ3 selective pro-apoptotic peptide as potential carrier for drug delivery into melanoma metastatic cells (2014) PLoS One, 9, p. e106441
Lim, E.H., Danthi, N., Bednarski, M., Li, K.C.P., A review: Integrin αvβ3-targeted molecular imaging and therapy in angiogenesis (2005) Nanomed.: Nanotechnol., Biol., Med., 1, pp. 110-114
Jia, Z., Song, L., Zang, F., Song, J., Zhang, W., Yan, C., Xie, J., Zhang, Y., Active-target T1-weighted MR Imaging of Tiny Hepatic Tumor via RGD Modified Ultra-small Fe3O4 Nanoprobes (2016) Theranostics, 6, pp. 1780-1791
NIR Emitting Nanoprobes Based on Cyclic RGD Motif Conjugated PbS Quantum Dots for Integrin-Targeted Optical Bioimaging
Here, silica-coated PbS quantum dots (QDs) with photoluminescence emission properties in the near-infrared (NIR) region are proposed as potential effective single particle optical nanoprobes for future in vivo imaging of tumors. The dispersibility in aqueous medium of hydrophobic PbS QDs was accomplished by growing a silica shell on their surface by exploiting a base assisted water-in-oil microemulsion method. The silica-coated PbS QDs were then conjugated with a specifically designed cyclic arginine-glycine-aspartic acid (cRGD) peptide that is able to specifically recognize αvβ3 integrins, which are overexpressed in angiogenic tumor-induced vasculatures and on some solid tumors, to achieve tumor-specific targeting. The cRGD peptide PbS silica-coated QDs were systematically characterized, at each step of their preparation, by means of complementary optical and structural techniques, demonstrating appropriate colloidal stability and the maintenance of their optical futures in aqueous solutions. The cellular uptake of cRGD peptide functionalized luminescent nanostructures in human melanoma cells, where overexpression of αvβ3 was observed, was assessed by means of confocal microscopy analysis and cytometric study. The selectivity of the cRGD peptide PbS silica-coated QDs for the αvβ3 integrin was established, consequently highlighting the significant potential of the developed NIR emitting nanostructures as optically traceable nanoprobes for future αvβ3 integrin receptor in vivo targeting in the NIR region. © 2017 American Chemical Society.
Here, silica-coated PbS quantum dots (QDs) with photoluminescence emission properties in the near-infrared (NIR) region are proposed as potential effective single particle optical nanoprobes for future in vivo imaging of tumors. The dispersibility in aqueous medium of hydrophobic PbS QDs was accomplished by growing a silica shell on their surface by exploiting a base assisted water-in-oil microemulsion method. The silica-coated PbS QDs were then conjugated with a specifically designed cyclic arginine-glycine-aspartic acid (cRGD) peptide that is able to specifically recognize αvβ3 integrins, which are overexpressed in angiogenic tumor-induced vasculatures and on some solid tumors, to achieve tumor-specific targeting. The cRGD peptide PbS silica-coated QDs were systematically characterized, at each step of their preparation, by means of complementary optical and structural techniques, demonstrating appropriate colloidal stability and the maintenance of their optical futures in aqueous solutions. The cellular uptake of cRGD peptide functionalized luminescent nanostructures in human melanoma cells, where overexpression of αvβ3 was observed, was assessed by means of confocal microscopy analysis and cytometric study. The selectivity of the cRGD peptide PbS silica-coated QDs for the αvβ3 integrin was established, consequently highlighting the significant potential of the developed NIR emitting nanostructures as optically traceable nanoprobes for future αvβ3 integrin receptor in vivo targeting in the NIR region. © 2017 American Chemical Society.
NIR Emitting Nanoprobes Based on Cyclic RGD Motif Conjugated PbS Quantum Dots for Integrin-Targeted Optical Bioimaging
No results. |
NIR Emitting Nanoprobes Based on Cyclic RGD Motif Conjugated PbS Quantum Dots for Integrin-Targeted Optical Bioimaging
Other filter: ([btitle,keywords] "Nir Emitting Quantum ...
Camorani S, Fedele M, Zannetti A, Cerchia L
* TNBC Challenge: Oligonucleotide Aptamers for New Imaging and Therapy Modalities (339 views) (PDF 121 views)
Pharmaceuticals (ISSN: 1424-8247print, 1424-8247linking), 2018 Nov 13; 11(4): N/D-N/D.
Impact Factor: 4.286
View Export to BibTeX Export to EndNote
Camorani S, Hill B, Collina F, Gargiulo S, Napolitano M, Cantile M, Di Bonito M, Botti G, Fedele M, Zannetti A, Cerchia L
* Targeted imaging and inhibition of triple-negative breast cancer metastases by a PDGFRβ aptamer (619 views) (PDF 136 views)
Theranostics (ISSN: 1838-7640, 1838-7640electronic, 1838-7640linking), 2018 Oct 6; 8(18): 5178-5199.
Impact Factor: 8.537
View Export to BibTeX Export to EndNote
Di Pietro P, Zaccaro L, Comegna D, Del Gatto A, Saviano M, Snyders R, Cossement D, Satriano C, Rizzarelli E
* Silver nanoparticles functionalized with a fluorescent cyclic RGD peptide: a versatile integrin targeting platform for cells and bacteria (311 views) (PDF 162 views)
The Royal Society Of Chemistry, 2016 Jan 01; 6: N/D-N/D.
Impact Factor: 3.564
View Export to BibTeX Export to EndNote
Valente G, Depalo N, De Paola I, Iacobazzi RM, Denora N, Laquintana V, Comparelli R, Altamura E, Latronico T, Altomare M, Fanizza E, Striccoli M, Agostiano A, Saviano M, Del Gatto A, Zaccaro L, Curri ML
* Integrin-targeting with peptide-bioconjugated semiconductor-magnetic nanocrystalline heterostructures (387 views)
Nano Res (ISSN: 1998-0124), 2016; 9(3): 644-662.
Impact Factor: 7.354
View Export to BibTeX Export to EndNote
* TNBC Challenge: Oligonucleotide Aptamers for New Imaging and Therapy Modalities (339 views) (PDF 121 views)
Pharmaceuticals (ISSN: 1424-8247print, 1424-8247linking), 2018 Nov 13; 11(4): N/D-N/D.
Impact Factor: 4.286
View Export to BibTeX Export to EndNote
Camorani S, Hill B, Collina F, Gargiulo S, Napolitano M, Cantile M, Di Bonito M, Botti G, Fedele M, Zannetti A, Cerchia L
* Targeted imaging and inhibition of triple-negative breast cancer metastases by a PDGFRβ aptamer (619 views) (PDF 136 views)
Theranostics (ISSN: 1838-7640, 1838-7640electronic, 1838-7640linking), 2018 Oct 6; 8(18): 5178-5199.
Impact Factor: 8.537
View Export to BibTeX Export to EndNote
Di Pietro P, Zaccaro L, Comegna D, Del Gatto A, Saviano M, Snyders R, Cossement D, Satriano C, Rizzarelli E
* Silver nanoparticles functionalized with a fluorescent cyclic RGD peptide: a versatile integrin targeting platform for cells and bacteria (311 views) (PDF 162 views)
The Royal Society Of Chemistry, 2016 Jan 01; 6: N/D-N/D.
Impact Factor: 3.564
View Export to BibTeX Export to EndNote
Valente G, Depalo N, De Paola I, Iacobazzi RM, Denora N, Laquintana V, Comparelli R, Altamura E, Latronico T, Altomare M, Fanizza E, Striccoli M, Agostiano A, Saviano M, Del Gatto A, Zaccaro L, Curri ML
* Integrin-targeting with peptide-bioconjugated semiconductor-magnetic nanocrystalline heterostructures (387 views)
Nano Res (ISSN: 1998-0124), 2016; 9(3): 644-662.
Impact Factor: 7.354
View Export to BibTeX Export to EndNote
4 Records (4 excluding Abstracts).
Total impact factor: 23.741 (23.741 excluding Abstracts).
Total 5 year impact factor: 16.901 (16.901 excluding Abstracts).
Total impact factor: 23.741 (23.741 excluding Abstracts).
Total 5 year impact factor: 16.901 (16.901 excluding Abstracts).
416 views. Last view on Friday 17 February 2023, 8:16:55
ibb.cnr.it
