Flip-angle based ratiometric approach for pulsed CEST-MRI pH imaging (322 views)
J Magn Reson (ISSN: 1090-7807, 1090-7807linking), 2017 Dec 11; 287: 1-9.
Export to BibTeX Export to EndNote
Paper type: Journal Article,
Impact factor: 2.586, 5-year impact factor: 2.731
Url: https://www.scopus.com/inward/record.uri?eid=2-s2.0-85038381596&doi=10.1016%2fj.jmr.2017.12.007&partnerID=40&md5=6e6918ba32642d221872a472861009cb
Keywords: Cest, Contrast Media, Iodinated Contrast Media, Pulsed-Cest, Radiographic Agents, Train Pulses, Magnetic Resonance Imaging, Ph Sensors, Chemical Exchange, Chemical Exchange Saturation Transfer, Clinical Scanners, Physiological Range,
Affiliations:
*** IBB - CNR ***
Dipartimento di Biotecnologie Molecolari e Scienze per la Salute, Universita degli Studi di Torino, Torino, Italy., CRB Bracco Imaging S.p.A., Via Ribes 5, Colleretto Giacosa (TO), Italy., Department of High-field Magnetic Resonance, Max Planck Institute for Biological Cybernetics, Tubingen, Germany., Dipartimento di Biotecnologie Molecolari e Scienze per la Salute, Universita degli Studi di Torino, Torino, Italy; Consiglio Nazionale delle Ricerche (CNR), Istituto di Biostrutture e Bioimmagini, Torino, Italy. Electronic address: dario.longo@unito.it.,
References:
van Zijl, P.C., Yadav, N.N., Chemical exchange saturation transfer (CEST): what is in a name and what isn't? (2011) Magn. Reson. Med., 65, pp. 927-94
Liu, G., Song, X., Chan, K.W., McMahon, M.T., Nuts and bolts of chemical exchange saturation transfer MRI (2013) NMR Biomed., 26, pp. 810-828
Vinogradov, E., Sherry, A.D., Lenkinski, R.E., CEST: from basic principles to applications, challenges and opportunities (2013) J. Magn. Reson., 229, pp. 155-172
Jones, C.K., Schlosser, M.J., van Zijl, P.C., Pomper, M.G., Golay, X., Zhou, J., Amide proton transfer imaging of human brain tumors at 3T (2006) Magn. Reson. Med., 56, pp. 585-592
van Zijl, P.C., Jones, C.K., Ren, J., Malloy, C.R., Sherry, A.D., MRI detection of glycogen in vivo by using chemical exchange saturation transfer imaging (glycoCEST) (2007) Proc. Natl. Acad. Sci. USA, 104, pp. 4359-4364
Nasrallah, F.A., Pages, G., Kuchel, P.W., Golay, X., Chuang, K.H., Imaging brain deoxyglucose uptake and metabolism by glucoCEST MRI (2013) J. Cereb. Blood Flow Metab., 33, pp. 1270-1278
Rivlin, M., Horev, J., Tsarfaty, I., Navon, G., Molecular imaging of tumors and metastases using chemical exchange saturation transfer (CEST) MRI (2013) Sci. Rep., 3, p. 3045
Delli Castelli, D., Terreno, E., Aime, S., Yb(III)-HPDO3A: a dual pH- and temperature-responsive CEST agent (2011) Angew. Chem. Int. Ed. Engl., 50, pp. 1798-1800
Dastru, W., Longo, D., Aime, S., Contrast agents and mechanisms (2011) Drug Discov. Today: Technol., 8, pp. e109-e115
Wang, X., Wu, Y., Soesbe, T.C., Yu, J., Zhao, P., Kiefer, G.E., Sherry, A.D., A pH-responsive MRI agent that can be activated beyond the tissue magnetization transfer window (2015) Angew. Chem. Int. Ed. In Engl., 54, pp. 8662-8664
Rivlin, M., Navon, G., Glucosamine and N-acetyl glucosamine as new CEST MRI agents for molecular imaging of tumors (2016) Sci. Rep., 6, p. 32648
Rivlin, M., Tsarfaty, I., Navon, G., Functional molecular imaging of tumors by chemical exchange saturation transfer MRI of 3-O-Methyl-D-glucose (2014) Magn. Reson. Med., 72, pp. 1375-1380
Bar-Shir, A., Bulte, J.W., Gilad, A.A., Molecular engineering of nonmetallic biosensors for CEST MRI (2015) ACS Chem. Biol., 10, pp. 1160-1170
Sun, P.Z., Zhou, J., Huang, J., van Zijl, P., Simplified quantitative description of amide proton transfer (APT) imaging during acute ischemia (2007) Magn. Reson. Med., 57, pp. 405-410
Zaiss, M., Windschuh, J., Paech, D., Meissner, J.E., Burth, S., Schmitt, B., Kickingereder, P., Radbruch, A., Relaxation-compensated CEST-MRI of the human brain at 7T: unbiased insight into NOE and amide signal changes in human glioblastoma (2015) Neuroimage, 112, pp. 180-188
Longo, D.L., Moustaghfir, F.Z., Zerbo, A., Consolino, L., Anemone, A., Bracesco, M., Aime, S., EXCI-CEST: exploiting pharmaceutical excipients as MRI-CEST contrast agents for tumor imaging (2017) Int. J. Pharmaceut., 525, pp. 275-281
Ferrauto, G., Delli Castelli, D., Di Gregorio, E., Langereis, S., Burdinski, D., Grull, H., Terreno, E., Aime, S., Lanthanide-loaded erythrocytes as highly sensitive chemical exchange saturation transfer MRI contrast agents (2014) J. Am. Chem. Soc., 136, pp. 638-641
Liu, G., Bettegowda, C., Qiao, Y., Staedtke, V., Chan, K.W., Bai, R., Li, Y., van Zijl, P.C., Noninvasive imaging of infection after treatment with tumor-homing bacteria using Chemical Exchange Saturation Transfer (CEST) MRI (2013) Magn. Reson. Med., 70, pp. 1690-1698
Longo, D.L., Di Gregorio, E., Abategiovanni, R., Ceccon, A., Assfalg, M., Molinari, H., Aime, S., Chemical exchange saturation transfer (CEST): an efficient tool for detecting molecular information on proteins' behaviour (2014) Analyst, 139, pp. 2687-2690
Ceccon, A., D'Onofrio, M., Zanzoni, S., Longo, D.L., Aime, S., Molinari, H., Assfalg, M., NMR investigation of the equilibrium partitioning of a water-soluble bile salt protein carrier to phospholipid vesicles (2013) Proteins, 81, pp. 1776-1791
Zaiss, M., Kunz, P., Goerke, S., Radbruch, A., Bachert, P., MR imaging of protein folding in vitro employing nuclear-Overhauser-mediated saturation transfer (2013) NMR Biomed., 26, pp. 1815-1822
Cai, K., Haris, M., Singh, A., Kogan, F., Greenberg, J.H., Hariharan, H., Detre, J.A., Reddy, R., Magnetic resonance imaging of glutamate (2012) Nat. Med., 18, pp. 302-306
Kogan, F., Haris, M., Singh, A., Cai, K., Debrosse, C., Nanga, R.P., Hariharan, H., Reddy, R., Method for high-resolution imaging of creatine in vivo using chemical exchange saturation transfer (2014) Magn. Reson. Med., 71, pp. 164-172
Tsitovich, P.B., Burns, P.J., McKay, A.M., Morrow, J.R., Redox-activated MRI contrast agents based on lanthanide and transition metal ions (2014) J. Inorgan. Biochem., 133, pp. 143-154
Funk, A.M., Clavijo Jordan, V., Sherry, A.D., Ratnakar, S.J., Kovacs, Z., Oxidative conversion of a Europium(II)-based T1 agent into a Europium(III)-Based paraCEST agent that can be detected in vivo by magnetic resonance imaging (2016) Angew. Chem. Int. Ed. In Engl., 55, pp. 5024-5027
Bar-Shir, A., Liu, G., Greenberg, M.M., Bulte, J.W., Gilad, A.A., Synthesis of a probe for monitoring HSV1-tk reporter gene expression using chemical exchange saturation transfer MRI (2013) Nat. Protoc., 8, pp. 2380-2391
Liu, G., Liang, Y., Bar-Shir, A., Chan, K.W., Galpoththawela, C.S., Bernard, S.M., Tse, T., Gilad, A.A., Monitoring enzyme activity using a diamagnetic chemical exchange saturation transfer magnetic resonance imaging contrast agent (2011) J. Am. Chem. Soc., 133, pp. 16326-16329
Aime, S., Delli Castelli, D., Terreno, E., Novel pH-reporter MRI contrast agents (2002) Angew. Chem. Int. Ed. Engl., 41, pp. 4334-4336
Geraldes, C.F., Laurent, S., Classification and basic properties of contrast agents for magnetic resonance imaging (2009) Contrast Media Mol. Imag., 4, pp. 1-23
Hingorani, D.V., Bernstein, A.S., Pagel, M.D., A review of responsive MRI contrast agents: 2005–2014 (2015) Contrast Media Mol. Imag., 10, pp. 245-265
Longo, D.L., Dastru, W., Digilio, G., Keupp, J., Langereis, S., Lanzardo, S., Prestigio, S., Aime, S., Iopamidol as a responsive MRI-chemical exchange saturation transfer contrast agent for pH mapping of kidneys: In vivo studies in mice at 7 T (2011) Magn. Reson. Med., 65, pp. 202-211
Longo, D.L., Busato, A., Lanzardo, S., Antico, F., Aime, S., Imaging the pH evolution of an acute kidney injury model by means of iopamidol, a MRI-CEST pH-responsive contrast agent (2013) Magn. Reson. Med., 70, pp. 859-864
Longo, D.L., Bartoli, A., Consolino, L., Bardini, P., Arena, F., Schwaiger, M., Aime, S., In vivo imaging of tumor metabolism and acidosis by combining PET and MRI-CEST pH imaging (2016) Cancer Res., 76, pp. 6463-6470
Longo, D.L., Cutrin, J.C., Michelotti, F., Irrera, P., Aime, S., Noninvasive evaluation of renal pH homeostasis after ischemia reperfusion injury by CEST-MRI (2017) NMR Biomed., 30
Chen, L.Q., Howison, C.M., Jeffery, J.J., Robey, I.F., Kuo, P.H., Pagel, M.D., Evaluations of extracellular pH within in vivo tumors using acidoCEST MRI (2014) Magn. Reson. Med., 72, pp. 1408-1417
Yang, X., Song, X., Ray Banerjee, S., Li, Y., Byun, Y., Liu, G., Bhujwalla, Z.M., McMahon, M.T., Developing imidazoles as CEST MRI pH sensors (2016) Contrast Media Mol. Imag., 11, pp. 304-312
Ward, K.M., Balaban, R.S., Determination of pH using water protons and chemical exchange dependent saturation transfer (CEST) (2000) Magn. Reson. Med., 44, pp. 799-802
Longo, D.L., Sun, P.Z., Consolino, L., Michelotti, F.C., Uggeri, F., Aime, S., A general MRI-CEST ratiometric approach for pH imaging: demonstration of in vivo pH mapping with lobitridol (2014) J. Am. Chem. Soc., 136, pp. 14333-14336
Sun, P.Z., Benner, T., Kumar, A., Sorensen, A.G., Investigation of optimizing and translating pH-sensitive pulsed-chemical exchange saturation transfer (CEST) imaging to a 3T clinical scanner (2008) Magn. Reson. Med., 60, pp. 834-841
Schmitt, B., Zaiss, M., Zhou, J., Bachert, P., Optimization of pulse train presaturation for CEST imaging in clinical scanners (2011) Magn. Reson. Med., 65, pp. 1620-1629
Sun, P.Z., Wang, E., Cheung, J.S., Zhang, X., Benner, T., Sorensen, A.G., Simulation and optimization of pulsed radio frequency irradiation scheme for chemical exchange saturation transfer (CEST) MRI-demonstration of pH-weighted pulsed-amide proton CEST MRI in an animal model of acute cerebral ischemia (2011) Magn. Reson. Med., 66, pp. 1042-1048
Meissner, J.E., Goerke, S., Rerich, E., Klika, K.D., Radbruch, A., Ladd, M.E., Bachert, P., Zaiss, M., Quantitative pulsed CEST-MRI using Omega-plots (2015) NMR Biomed., 28, pp. 1196-1208
Yoshimaru, E.S., Randtke, E.A., Pagel, M.D., Cardenas-Rodriguez, J., Design and optimization of pulsed Chemical Exchange Saturation Transfer MRI using a multiobjective genetic algorithm (2016) J. Magn. Reson., 263, pp. 184-192
Tee, Y.K., Khrapitchev, A.A., Sibson, N.R., Payne, S.J., Chappell, M.A., Evaluating the use of a continuous approximation for model-based quantification of pulsed chemical exchange saturation transfer (CEST) (2012) J. Magn. Reson., 222, pp. 88-95
Desmond, K.L., Stanisz, G.J., Understanding quantitative pulsed CEST in the presence of MT (2012) Magn. Reson. Med., 67, pp. 979-990
Roeloffs, V., Meyer, C., Bachert, P., Zaiss, M., Towards quantification of pulsed spinlock and CEST at clinical MR scanners: an analytical interleaved saturation-relaxation (ISAR) approach (2015) NMR Biomed., 28, pp. 40-53
Jones, C.K., Polders, D., Hua, J., Zhu, H., Hoogduin, H.J., Zhou, J., Luijten, P., van Zijl, P.C., In vivo three-dimensional whole-brain pulsed steady-state chemical exchange saturation transfer at 7 T (2012) Magn. Reson. Med., 67, pp. 1579-1589
Desmond, K.L., Mehrabian, H., Chavez, S., Sahgal, A., Soliman, H., Rola, R., Stanisz, G.J., Chemical exchange saturation transfer for predicting response to stereotactic radiosurgery in human brain metastasis (2016) Magn. Reson. Med.
Stabinska, J., Cronenberg, T., Wittsack, H.J., Lanzman, R.S., Muller-Lutz, A., Quantitative pulsed CEST-MRI at a clinical 3T MRI system (2017) MAGMA
Zu, Z., Li, K., Janve, V.A., Does, M.D., Gochberg, D.F., Optimizing pulsed-chemical exchange saturation transfer imaging sequences (2011) Magn. Reson. Med., 66, pp. 1100-1108
Zu, Z., Janve, V.A., Li, K., Does, M.D., Gore, J.C., Gochberg, D.F., Multi-angle ratiometric approach to measure chemical exchange in amide proton transfer imaging (2012) Magn. Reson. Med., 68, pp. 711-719
Sun, P.Z., Simplified and scalable numerical solution for describing multi-pool chemical exchange saturation transfer (CEST) MRI contrast (2010) J. Magn. Reson., 205, pp. 235-241
Woessner, D.E., Zhang, S., Merritt, M.E., Sherry, A.D., Numerical solution of the Bloch equations provides insights into the optimum design of PARACEST agents for MRI (2005) Magn. Reson. Med., 53, pp. 790-799
Sun, P.Z., Longo, D.L., Hu, W., Xiao, G., Wu, R., Quantification of iopamidol multi-site chemical exchange properties for ratiometric chemical exchange saturation transfer (CEST) imaging of pH (2014) Phys. Med. Biol., 59, pp. 4493-4504
Longo, D.L., Michelotti, F., Consolino, L., Bardini, P., Digilio, G., Xiao, G., Sun, P.Z., Aime, S., In vitro and in vivo assessment of nonionic iodinated radiographic molecules as chemical exchange saturation transfer magnetic resonance imaging tumor perfusion agents (2016) Invest. Radiol., 51, pp. 155-162
Ramani, A., Dalton, C., Miller, D.H., Tofts, P.S., Barker, G.J., Precise estimate of fundamental in-vivo MT parameters in human brain in clinically feasible times (2002) Magn. Reson. Imag., 20, pp. 721-731
Stancanello, J., Terreno, E., Castelli, D.D., Cabella, C., Uggeri, F., Aime, S., Development and validation of a smoothing-splines-based correction method for improving the analysis of CEST-MR images (2008) Contrast Media Mol. Imag., 3, pp. 136-149
Anemone, A., Consolino, L., Longo, D.L., MRI-CEST assessment of tumour perfusion using X-ray iodinated agents: comparison with a conventional Gd-based agent (2017) Eur. Radiol., 27, pp. 2170-2179
Woods, M., Woessner, D.E., Sherry, A.D., Paramagnetic lanthanide complexes as PARACEST agents for medical imaging (2006) Chem. Soc. Rev., 35, pp. 500-511
Sherry, A.D., Wu, Y., The importance of water exchange rates in the design of responsive agents for MRI (2013) Curr. Opin. Chem. Biol, 17, pp. 167-174
Khlebnikov, V., Geades, N., Klomp, D.W.J., Hoogduin, H., Gowland, P., Mougin, O., Comparison of pulsed three-dimensional CEST acquisition schemes at 7 tesla: steady state versus pseudosteady state (2017) Magn. Reson. Med., 77, pp. 2280-2287
Ward, K.M., Aletras, A.H., Balaban, R.S., A new class of contrast agents for MRI based on proton chemical exchange dependent saturation transfer (CEST) (2000) J. Magn. Reson., 143, pp. 79-87
Moon, B.F., Jones, K.M., Chen, L.Q., Liu, P., Randtke, E.A., Howison, C.M., Pagel, M.D., A comparison of iopromide and iopamidol, two acidoCEST MRI contrast media that measure tumor extracellular pH (2015) Contrast Media Mol. Imag., 10, pp. 446-455
Wu, R., Longo, D.L., Aime, S., Sun, P.Z., Quantitative description of radiofrequency (RF) power-based ratiometric chemical exchange saturation transfer (CEST) pH imaging (2015) NMR Biomed., 28, pp. 555-565
Wu, Y., Zhang, S., Soesbe, T.C., Yu, J., Vinogradov, E., Lenkinski, R.E., Sherry, A.D., pH imaging of mouse kidneys in vivo using a frequency-dependent paraCEST agent (2016) Magn. Reson. Med., 75, pp. 2432-2441
Tsitovich, P.B., Cox, J.M., Spernyak, J.A., Morrow, J.R., Gear up for a pH shift: a responsive Iron(II) 2-amino-6-picolyl-appended macrocyclic paraCEST agent that protonates at a pendent group (2016) Inorg. Chem., 55, pp. 12001-12010
Muller-Lutz, A., Khalil, N., Schmitt, B., Jellus, V., Pentang, G., Oeltzschner, G., Antoch, G., Wittsack, H.J., Pilot study of Iopamidol-based quantitative pH imaging on a clinical 3T MR scanner (2014) MAGMA, 27, pp. 477-485
Jones, K.M., Randtke, E.A., Yoshimaru, E.S., Howison, C.M., Chalasani, P., Klein, R.R., Chambers, S.K., Pagel, M.D., Clinical translation of tumor acidosis measurements with AcidoCEST MRI (2017) Mol. Imag. Biol., 19, pp. 617-625
Xu, X., Yadav, N.N., Song, X., McMahon, M.T., Jerschow, A., van Zijl, P.C., Xu, J., Screening CEST contrast agents using ultrafast CEST imaging (2016) J. Magn. Reson., 265, pp. 224-229
Dopfert, J., Zaiss, M., Witte, C., Schroder, L., Ultrafast CEST imaging (2014) J. Magn. Reson., 243, pp. 47-53
Varma, G., Lenkinski, R.E., Vinogradov, E., Keyhole chemical exchange saturation transfer (2012) Magn. Reson. Med., 68, pp. 1228-1233
Windschuh, J., Zaiss, M., Meissner, J.E., Paech, D., Radbruch, A., Ladd, M.E., Bachert, P., Correction of B1-inhomogeneities for relaxation-compensated CEST imaging at 7 T (2015) NMR Biomed., 28, pp. 529-537
Tse, D.H.Y., da Silva, N.A., Poser, B.A., Shah, N.J., B1+ inhomogeneity mitigation in CEST using parallel transmission (2017) Magn. Reson. Med., 78, pp. 2216-2225
J Magn Reson (ISSN: 1090-7807, 1090-7807linking), 2017 Dec 11; 287: 1-9.
Export to BibTeX Export to EndNote
Paper type: Journal Article,
Impact factor: 2.586, 5-year impact factor: 2.731
Url: https://www.scopus.com/inward/record.uri?eid=2-s2.0-85038381596&doi=10.1016%2fj.jmr.2017.12.007&partnerID=40&md5=6e6918ba32642d221872a472861009cb
Keywords: Cest, Contrast Media, Iodinated Contrast Media, Pulsed-Cest, Radiographic Agents, Train Pulses, Magnetic Resonance Imaging, Ph Sensors, Chemical Exchange, Chemical Exchange Saturation Transfer, Clinical Scanners, Physiological Range,
Affiliations:
*** IBB - CNR ***
Dipartimento di Biotecnologie Molecolari e Scienze per la Salute, Universita degli Studi di Torino, Torino, Italy., CRB Bracco Imaging S.p.A., Via Ribes 5, Colleretto Giacosa (TO), Italy., Department of High-field Magnetic Resonance, Max Planck Institute for Biological Cybernetics, Tubingen, Germany., Dipartimento di Biotecnologie Molecolari e Scienze per la Salute, Universita degli Studi di Torino, Torino, Italy; Consiglio Nazionale delle Ricerche (CNR), Istituto di Biostrutture e Bioimmagini, Torino, Italy. Electronic address: dario.longo@unito.it.,
References:
van Zijl, P.C., Yadav, N.N., Chemical exchange saturation transfer (CEST): what is in a name and what isn't? (2011) Magn. Reson. Med., 65, pp. 927-94
Liu, G., Song, X., Chan, K.W., McMahon, M.T., Nuts and bolts of chemical exchange saturation transfer MRI (2013) NMR Biomed., 26, pp. 810-828
Vinogradov, E., Sherry, A.D., Lenkinski, R.E., CEST: from basic principles to applications, challenges and opportunities (2013) J. Magn. Reson., 229, pp. 155-172
Jones, C.K., Schlosser, M.J., van Zijl, P.C., Pomper, M.G., Golay, X., Zhou, J., Amide proton transfer imaging of human brain tumors at 3T (2006) Magn. Reson. Med., 56, pp. 585-592
van Zijl, P.C., Jones, C.K., Ren, J., Malloy, C.R., Sherry, A.D., MRI detection of glycogen in vivo by using chemical exchange saturation transfer imaging (glycoCEST) (2007) Proc. Natl. Acad. Sci. USA, 104, pp. 4359-4364
Nasrallah, F.A., Pages, G., Kuchel, P.W., Golay, X., Chuang, K.H., Imaging brain deoxyglucose uptake and metabolism by glucoCEST MRI (2013) J. Cereb. Blood Flow Metab., 33, pp. 1270-1278
Rivlin, M., Horev, J., Tsarfaty, I., Navon, G., Molecular imaging of tumors and metastases using chemical exchange saturation transfer (CEST) MRI (2013) Sci. Rep., 3, p. 3045
Delli Castelli, D., Terreno, E., Aime, S., Yb(III)-HPDO3A: a dual pH- and temperature-responsive CEST agent (2011) Angew. Chem. Int. Ed. Engl., 50, pp. 1798-1800
Dastru, W., Longo, D., Aime, S., Contrast agents and mechanisms (2011) Drug Discov. Today: Technol., 8, pp. e109-e115
Wang, X., Wu, Y., Soesbe, T.C., Yu, J., Zhao, P., Kiefer, G.E., Sherry, A.D., A pH-responsive MRI agent that can be activated beyond the tissue magnetization transfer window (2015) Angew. Chem. Int. Ed. In Engl., 54, pp. 8662-8664
Rivlin, M., Navon, G., Glucosamine and N-acetyl glucosamine as new CEST MRI agents for molecular imaging of tumors (2016) Sci. Rep., 6, p. 32648
Rivlin, M., Tsarfaty, I., Navon, G., Functional molecular imaging of tumors by chemical exchange saturation transfer MRI of 3-O-Methyl-D-glucose (2014) Magn. Reson. Med., 72, pp. 1375-1380
Bar-Shir, A., Bulte, J.W., Gilad, A.A., Molecular engineering of nonmetallic biosensors for CEST MRI (2015) ACS Chem. Biol., 10, pp. 1160-1170
Sun, P.Z., Zhou, J., Huang, J., van Zijl, P., Simplified quantitative description of amide proton transfer (APT) imaging during acute ischemia (2007) Magn. Reson. Med., 57, pp. 405-410
Zaiss, M., Windschuh, J., Paech, D., Meissner, J.E., Burth, S., Schmitt, B., Kickingereder, P., Radbruch, A., Relaxation-compensated CEST-MRI of the human brain at 7T: unbiased insight into NOE and amide signal changes in human glioblastoma (2015) Neuroimage, 112, pp. 180-188
Longo, D.L., Moustaghfir, F.Z., Zerbo, A., Consolino, L., Anemone, A., Bracesco, M., Aime, S., EXCI-CEST: exploiting pharmaceutical excipients as MRI-CEST contrast agents for tumor imaging (2017) Int. J. Pharmaceut., 525, pp. 275-281
Ferrauto, G., Delli Castelli, D., Di Gregorio, E., Langereis, S., Burdinski, D., Grull, H., Terreno, E., Aime, S., Lanthanide-loaded erythrocytes as highly sensitive chemical exchange saturation transfer MRI contrast agents (2014) J. Am. Chem. Soc., 136, pp. 638-641
Liu, G., Bettegowda, C., Qiao, Y., Staedtke, V., Chan, K.W., Bai, R., Li, Y., van Zijl, P.C., Noninvasive imaging of infection after treatment with tumor-homing bacteria using Chemical Exchange Saturation Transfer (CEST) MRI (2013) Magn. Reson. Med., 70, pp. 1690-1698
Longo, D.L., Di Gregorio, E., Abategiovanni, R., Ceccon, A., Assfalg, M., Molinari, H., Aime, S., Chemical exchange saturation transfer (CEST): an efficient tool for detecting molecular information on proteins' behaviour (2014) Analyst, 139, pp. 2687-2690
Ceccon, A., D'Onofrio, M., Zanzoni, S., Longo, D.L., Aime, S., Molinari, H., Assfalg, M., NMR investigation of the equilibrium partitioning of a water-soluble bile salt protein carrier to phospholipid vesicles (2013) Proteins, 81, pp. 1776-1791
Zaiss, M., Kunz, P., Goerke, S., Radbruch, A., Bachert, P., MR imaging of protein folding in vitro employing nuclear-Overhauser-mediated saturation transfer (2013) NMR Biomed., 26, pp. 1815-1822
Cai, K., Haris, M., Singh, A., Kogan, F., Greenberg, J.H., Hariharan, H., Detre, J.A., Reddy, R., Magnetic resonance imaging of glutamate (2012) Nat. Med., 18, pp. 302-306
Kogan, F., Haris, M., Singh, A., Cai, K., Debrosse, C., Nanga, R.P., Hariharan, H., Reddy, R., Method for high-resolution imaging of creatine in vivo using chemical exchange saturation transfer (2014) Magn. Reson. Med., 71, pp. 164-172
Tsitovich, P.B., Burns, P.J., McKay, A.M., Morrow, J.R., Redox-activated MRI contrast agents based on lanthanide and transition metal ions (2014) J. Inorgan. Biochem., 133, pp. 143-154
Funk, A.M., Clavijo Jordan, V., Sherry, A.D., Ratnakar, S.J., Kovacs, Z., Oxidative conversion of a Europium(II)-based T1 agent into a Europium(III)-Based paraCEST agent that can be detected in vivo by magnetic resonance imaging (2016) Angew. Chem. Int. Ed. In Engl., 55, pp. 5024-5027
Bar-Shir, A., Liu, G., Greenberg, M.M., Bulte, J.W., Gilad, A.A., Synthesis of a probe for monitoring HSV1-tk reporter gene expression using chemical exchange saturation transfer MRI (2013) Nat. Protoc., 8, pp. 2380-2391
Liu, G., Liang, Y., Bar-Shir, A., Chan, K.W., Galpoththawela, C.S., Bernard, S.M., Tse, T., Gilad, A.A., Monitoring enzyme activity using a diamagnetic chemical exchange saturation transfer magnetic resonance imaging contrast agent (2011) J. Am. Chem. Soc., 133, pp. 16326-16329
Aime, S., Delli Castelli, D., Terreno, E., Novel pH-reporter MRI contrast agents (2002) Angew. Chem. Int. Ed. Engl., 41, pp. 4334-4336
Geraldes, C.F., Laurent, S., Classification and basic properties of contrast agents for magnetic resonance imaging (2009) Contrast Media Mol. Imag., 4, pp. 1-23
Hingorani, D.V., Bernstein, A.S., Pagel, M.D., A review of responsive MRI contrast agents: 2005–2014 (2015) Contrast Media Mol. Imag., 10, pp. 245-265
Longo, D.L., Dastru, W., Digilio, G., Keupp, J., Langereis, S., Lanzardo, S., Prestigio, S., Aime, S., Iopamidol as a responsive MRI-chemical exchange saturation transfer contrast agent for pH mapping of kidneys: In vivo studies in mice at 7 T (2011) Magn. Reson. Med., 65, pp. 202-211
Longo, D.L., Busato, A., Lanzardo, S., Antico, F., Aime, S., Imaging the pH evolution of an acute kidney injury model by means of iopamidol, a MRI-CEST pH-responsive contrast agent (2013) Magn. Reson. Med., 70, pp. 859-864
Longo, D.L., Bartoli, A., Consolino, L., Bardini, P., Arena, F., Schwaiger, M., Aime, S., In vivo imaging of tumor metabolism and acidosis by combining PET and MRI-CEST pH imaging (2016) Cancer Res., 76, pp. 6463-6470
Longo, D.L., Cutrin, J.C., Michelotti, F., Irrera, P., Aime, S., Noninvasive evaluation of renal pH homeostasis after ischemia reperfusion injury by CEST-MRI (2017) NMR Biomed., 30
Chen, L.Q., Howison, C.M., Jeffery, J.J., Robey, I.F., Kuo, P.H., Pagel, M.D., Evaluations of extracellular pH within in vivo tumors using acidoCEST MRI (2014) Magn. Reson. Med., 72, pp. 1408-1417
Yang, X., Song, X., Ray Banerjee, S., Li, Y., Byun, Y., Liu, G., Bhujwalla, Z.M., McMahon, M.T., Developing imidazoles as CEST MRI pH sensors (2016) Contrast Media Mol. Imag., 11, pp. 304-312
Ward, K.M., Balaban, R.S., Determination of pH using water protons and chemical exchange dependent saturation transfer (CEST) (2000) Magn. Reson. Med., 44, pp. 799-802
Longo, D.L., Sun, P.Z., Consolino, L., Michelotti, F.C., Uggeri, F., Aime, S., A general MRI-CEST ratiometric approach for pH imaging: demonstration of in vivo pH mapping with lobitridol (2014) J. Am. Chem. Soc., 136, pp. 14333-14336
Sun, P.Z., Benner, T., Kumar, A., Sorensen, A.G., Investigation of optimizing and translating pH-sensitive pulsed-chemical exchange saturation transfer (CEST) imaging to a 3T clinical scanner (2008) Magn. Reson. Med., 60, pp. 834-841
Schmitt, B., Zaiss, M., Zhou, J., Bachert, P., Optimization of pulse train presaturation for CEST imaging in clinical scanners (2011) Magn. Reson. Med., 65, pp. 1620-1629
Sun, P.Z., Wang, E., Cheung, J.S., Zhang, X., Benner, T., Sorensen, A.G., Simulation and optimization of pulsed radio frequency irradiation scheme for chemical exchange saturation transfer (CEST) MRI-demonstration of pH-weighted pulsed-amide proton CEST MRI in an animal model of acute cerebral ischemia (2011) Magn. Reson. Med., 66, pp. 1042-1048
Meissner, J.E., Goerke, S., Rerich, E., Klika, K.D., Radbruch, A., Ladd, M.E., Bachert, P., Zaiss, M., Quantitative pulsed CEST-MRI using Omega-plots (2015) NMR Biomed., 28, pp. 1196-1208
Yoshimaru, E.S., Randtke, E.A., Pagel, M.D., Cardenas-Rodriguez, J., Design and optimization of pulsed Chemical Exchange Saturation Transfer MRI using a multiobjective genetic algorithm (2016) J. Magn. Reson., 263, pp. 184-192
Tee, Y.K., Khrapitchev, A.A., Sibson, N.R., Payne, S.J., Chappell, M.A., Evaluating the use of a continuous approximation for model-based quantification of pulsed chemical exchange saturation transfer (CEST) (2012) J. Magn. Reson., 222, pp. 88-95
Desmond, K.L., Stanisz, G.J., Understanding quantitative pulsed CEST in the presence of MT (2012) Magn. Reson. Med., 67, pp. 979-990
Roeloffs, V., Meyer, C., Bachert, P., Zaiss, M., Towards quantification of pulsed spinlock and CEST at clinical MR scanners: an analytical interleaved saturation-relaxation (ISAR) approach (2015) NMR Biomed., 28, pp. 40-53
Jones, C.K., Polders, D., Hua, J., Zhu, H., Hoogduin, H.J., Zhou, J., Luijten, P., van Zijl, P.C., In vivo three-dimensional whole-brain pulsed steady-state chemical exchange saturation transfer at 7 T (2012) Magn. Reson. Med., 67, pp. 1579-1589
Desmond, K.L., Mehrabian, H., Chavez, S., Sahgal, A., Soliman, H., Rola, R., Stanisz, G.J., Chemical exchange saturation transfer for predicting response to stereotactic radiosurgery in human brain metastasis (2016) Magn. Reson. Med.
Stabinska, J., Cronenberg, T., Wittsack, H.J., Lanzman, R.S., Muller-Lutz, A., Quantitative pulsed CEST-MRI at a clinical 3T MRI system (2017) MAGMA
Zu, Z., Li, K., Janve, V.A., Does, M.D., Gochberg, D.F., Optimizing pulsed-chemical exchange saturation transfer imaging sequences (2011) Magn. Reson. Med., 66, pp. 1100-1108
Zu, Z., Janve, V.A., Li, K., Does, M.D., Gore, J.C., Gochberg, D.F., Multi-angle ratiometric approach to measure chemical exchange in amide proton transfer imaging (2012) Magn. Reson. Med., 68, pp. 711-719
Sun, P.Z., Simplified and scalable numerical solution for describing multi-pool chemical exchange saturation transfer (CEST) MRI contrast (2010) J. Magn. Reson., 205, pp. 235-241
Woessner, D.E., Zhang, S., Merritt, M.E., Sherry, A.D., Numerical solution of the Bloch equations provides insights into the optimum design of PARACEST agents for MRI (2005) Magn. Reson. Med., 53, pp. 790-799
Sun, P.Z., Longo, D.L., Hu, W., Xiao, G., Wu, R., Quantification of iopamidol multi-site chemical exchange properties for ratiometric chemical exchange saturation transfer (CEST) imaging of pH (2014) Phys. Med. Biol., 59, pp. 4493-4504
Longo, D.L., Michelotti, F., Consolino, L., Bardini, P., Digilio, G., Xiao, G., Sun, P.Z., Aime, S., In vitro and in vivo assessment of nonionic iodinated radiographic molecules as chemical exchange saturation transfer magnetic resonance imaging tumor perfusion agents (2016) Invest. Radiol., 51, pp. 155-162
Ramani, A., Dalton, C., Miller, D.H., Tofts, P.S., Barker, G.J., Precise estimate of fundamental in-vivo MT parameters in human brain in clinically feasible times (2002) Magn. Reson. Imag., 20, pp. 721-731
Stancanello, J., Terreno, E., Castelli, D.D., Cabella, C., Uggeri, F., Aime, S., Development and validation of a smoothing-splines-based correction method for improving the analysis of CEST-MR images (2008) Contrast Media Mol. Imag., 3, pp. 136-149
Anemone, A., Consolino, L., Longo, D.L., MRI-CEST assessment of tumour perfusion using X-ray iodinated agents: comparison with a conventional Gd-based agent (2017) Eur. Radiol., 27, pp. 2170-2179
Woods, M., Woessner, D.E., Sherry, A.D., Paramagnetic lanthanide complexes as PARACEST agents for medical imaging (2006) Chem. Soc. Rev., 35, pp. 500-511
Sherry, A.D., Wu, Y., The importance of water exchange rates in the design of responsive agents for MRI (2013) Curr. Opin. Chem. Biol, 17, pp. 167-174
Khlebnikov, V., Geades, N., Klomp, D.W.J., Hoogduin, H., Gowland, P., Mougin, O., Comparison of pulsed three-dimensional CEST acquisition schemes at 7 tesla: steady state versus pseudosteady state (2017) Magn. Reson. Med., 77, pp. 2280-2287
Ward, K.M., Aletras, A.H., Balaban, R.S., A new class of contrast agents for MRI based on proton chemical exchange dependent saturation transfer (CEST) (2000) J. Magn. Reson., 143, pp. 79-87
Moon, B.F., Jones, K.M., Chen, L.Q., Liu, P., Randtke, E.A., Howison, C.M., Pagel, M.D., A comparison of iopromide and iopamidol, two acidoCEST MRI contrast media that measure tumor extracellular pH (2015) Contrast Media Mol. Imag., 10, pp. 446-455
Wu, R., Longo, D.L., Aime, S., Sun, P.Z., Quantitative description of radiofrequency (RF) power-based ratiometric chemical exchange saturation transfer (CEST) pH imaging (2015) NMR Biomed., 28, pp. 555-565
Wu, Y., Zhang, S., Soesbe, T.C., Yu, J., Vinogradov, E., Lenkinski, R.E., Sherry, A.D., pH imaging of mouse kidneys in vivo using a frequency-dependent paraCEST agent (2016) Magn. Reson. Med., 75, pp. 2432-2441
Tsitovich, P.B., Cox, J.M., Spernyak, J.A., Morrow, J.R., Gear up for a pH shift: a responsive Iron(II) 2-amino-6-picolyl-appended macrocyclic paraCEST agent that protonates at a pendent group (2016) Inorg. Chem., 55, pp. 12001-12010
Muller-Lutz, A., Khalil, N., Schmitt, B., Jellus, V., Pentang, G., Oeltzschner, G., Antoch, G., Wittsack, H.J., Pilot study of Iopamidol-based quantitative pH imaging on a clinical 3T MR scanner (2014) MAGMA, 27, pp. 477-485
Jones, K.M., Randtke, E.A., Yoshimaru, E.S., Howison, C.M., Chalasani, P., Klein, R.R., Chambers, S.K., Pagel, M.D., Clinical translation of tumor acidosis measurements with AcidoCEST MRI (2017) Mol. Imag. Biol., 19, pp. 617-625
Xu, X., Yadav, N.N., Song, X., McMahon, M.T., Jerschow, A., van Zijl, P.C., Xu, J., Screening CEST contrast agents using ultrafast CEST imaging (2016) J. Magn. Reson., 265, pp. 224-229
Dopfert, J., Zaiss, M., Witte, C., Schroder, L., Ultrafast CEST imaging (2014) J. Magn. Reson., 243, pp. 47-53
Varma, G., Lenkinski, R.E., Vinogradov, E., Keyhole chemical exchange saturation transfer (2012) Magn. Reson. Med., 68, pp. 1228-1233
Windschuh, J., Zaiss, M., Meissner, J.E., Paech, D., Radbruch, A., Ladd, M.E., Bachert, P., Correction of B1-inhomogeneities for relaxation-compensated CEST imaging at 7 T (2015) NMR Biomed., 28, pp. 529-537
Tse, D.H.Y., da Silva, N.A., Poser, B.A., Shah, N.J., B1+ inhomogeneity mitigation in CEST using parallel transmission (2017) Magn. Reson. Med., 78, pp. 2216-2225
Flip-angle based ratiometric approach for pulsed CEST-MRI pH imaging
Several molecules have been exploited for developing MRI pH sensors based on the chemical exchange saturation transfer (CEST) technique. A ratiometric approach, based on the saturation of two exchanging pools at the same saturation power, or by varying the saturation power levels on the same pool, is usually needed to rule out the concentration term from the pH measurement. However, all these methods have been demonstrated by using a continuous wave saturation scheme that limits its translation to clinical scanners. This study shows a new ratiometric CEST-MRI pH-mapping approach based on a pulsed CEST saturation scheme for a radiographic contrast agent (iodixanol) possessing a single chemical exchange site. This approach is based on the ratio of the CEST contrast effects at two different flip angles combinations (180 degrees /360 degrees and 180 degrees /720 degrees ), keeping constant the mean irradiation RF power (Bavg power). The proposed ratiometric approach index is concentration independent and it showed good pH sensitivity and accuracy in the physiological range between 6.0 and 7.4.
Several molecules have been exploited for developing MRI pH sensors based on the chemical exchange saturation transfer (CEST) technique. A ratiometric approach, based on the saturation of two exchanging pools at the same saturation power, or by varying the saturation power levels on the same pool, is usually needed to rule out the concentration term from the pH measurement. However, all these methods have been demonstrated by using a continuous wave saturation scheme that limits its translation to clinical scanners. This study shows a new ratiometric CEST-MRI pH-mapping approach based on a pulsed CEST saturation scheme for a radiographic contrast agent (iodixanol) possessing a single chemical exchange site. This approach is based on the ratio of the CEST contrast effects at two different flip angles combinations (180 degrees /360 degrees and 180 degrees /720 degrees ), keeping constant the mean irradiation RF power (Bavg power). The proposed ratiometric approach index is concentration independent and it showed good pH sensitivity and accuracy in the physiological range between 6.0 and 7.4.
Flip-angle based ratiometric approach for pulsed CEST-MRI pH imaging
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Flip-angle based ratiometric approach for pulsed CEST-MRI pH imaging
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Impact Factor: 4.782
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Terreno E, Boffa C, Menchise V, Fedeli F, Carrera C, Castelli DD, Digilio G, Aime S
* Gadolinium-doped LipoCEST agents: A potential novel class of dual 1H-MRI probes (345 views)
Chem Commun (ISSN: 1359-7345, 1364-548x, 1364-548xelectronic), 2011 Apr 28; 47(16): 4667-4669.
Impact Factor: 6.169
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Accardo A, Morisco A, Tesauro D, Pedone C, Morelli G
* Naposomes: A new class of peptide-derivatized, target-selective multimodal nanoparticles for imaging and therapeutic applications (409 views)
Ther Deliv (ISSN: 2041-5990), 2011 Feb; 2(2): 235-257.
Impact Factor: 0
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Casciaro S, Conversano F, Ragusa A, Malvindi MA, Franchini R, Greco A, Pellegrino T, Gigli G
* Optimal enhancement configuration of silica nanoparticles for ultrasound imaging and automatic detection at conventional diagnostic frequencies (403 views)
Invest Radiol (ISSN: 0020-9996, 1536-0210, 1536-0210electronic), 2010 Nov; 45(11): 715-724.
Impact Factor: 4.67
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Maurea S, Mollica C, Imbriaco M, Fusari M, Camera L, Salvatore M
* Magnetic resonance cholangiography with mangafodipir trisodium in Caroli's disease with pancreas involvement (391 views)
Jop (ISSN: 1590-8577, 1590-0857), 2010 Sep 06; 11(5): 460-463.
Impact Factor: 0
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Digilio G, Menchise V, Gianolio E, Catanzaro V, Carrera C, Napolitano R, Fedeli F, Aime S
* Exofacial protein thiols as a route for the internalization of Gd(III)-based complexes for magnetic resonance imaging cell labeling (455 views)
J Med Chem (ISSN: 0022-2623, 1520-4804, 0022-2623print), 2010 Jul 8; 53(13): 4877-4890.
Impact Factor: 5.207
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Lanzillo R, Orefice G, Quarantelli M, Rinaldi C, Prinster A, Ventrella G, Spitaleri D, Lus G, Vacca G, Carotenuto B, Salvatore E, Brunetti A, Tedeschi G, Brescia Morra V
* Atorvastatin combined to interferon to verify the efficacy (ACTIVE) in relapsing-remitting active multiple sclerosis patients: A longitudinal controlled trial of combination therapy (561 views)
Mult Scler (ISSN: 1352-4585, 1477-0970, 1352-4585linking), 2010 Apr; 16(4): 450-454.
Impact Factor: 4.23
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Digilio G, Catanzaro V, Fedeli F, Gianolio E, Menchise V, Napolitano R, Gringeri C, Aime S
* Targeting exofacial protein thiols with Gd-III complexes. An efficient procedure for MRI cell labelling (345 views)
Chem Commun (ISSN: 1359-7345, 1364-548x, 1364-548xelectronic), 2009 Feb 28; (8): 893-895.
Impact Factor: 5.504
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Lapi F, Cecchi E, Pedone C, Attanasio F, Banchelli G, Vannacci A, Di Pirro M, Moschini M, Berni V, Matucci R, Cini E, Scalia A, Tendi E, Mugelli A
* Safety aspects of iodinated contrast media related to their physicochemical properties: A pharmacoepidemiology study in two Tuscany hospitals (494 views)
Eur J Clin Pharmacol Springer Verlag (ISSN: 0031-6970, 1432-1041), 2008 Jul; 64(7): 723-737.
Impact Factor: 2.497
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Ragozzino A, Lassandro F, De Ritis R, Imbriaco M
* Value of MRI in three patients with major vascular injuries after laparoscopic cholecystectomy (250 views)
Emergency Radiology (ISSN: 1070-3004), 2007 Nov; 14(6): 443-447.
Impact Factor: 6.214
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Berkouk K, Quarantelli M, Prinster A, Landeau B, Alfano B, Baron JC
* Mapping The Relative Contribution Of Gray Matter Activity Versus Volume In Brain Pet. A New Approach (390 views) (PDF 231 views)
J Neuroimaging (ISSN: 1051-2284, 1051-2284linking), 2006 Jul; 16(3): 224-235.
Impact Factor: 1.298
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Imbriaco M, Smeraldo D, Liuzzi R, Carrillo F, Cacace G, Vecchione D, Diglio A, Salvatore M
* Multislice CT with single-phase technique in patients with suspected pancreatic cancer (245 views)
Radiol Med (ISSN: 0033-8362, 1826-6983, 1826-6983electronic), 2006 Mar; 111(2): 159-166.
Impact Factor: 1.368
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Cuocolo A, Acampa W, Imbriaco M, De Luca N, Iovino GL, Salvatore M
* The many ways to myocardial perfusion imaging (478 views)
Q J Nucl Med Mol Im (ISSN: 1824-4785, 1824-4478, 1824-4785linking), 2005 Mar; 49(1): 4-18.
Impact Factor: 1.724
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Cirillo LC, Camera L, Della Noce M, Castiglione F, Mazzacca G, Salvatore M
Accuracy of enteroclysis in Crohn's disease of the small bowel: A retrospective study (472 views)
Eur Radiol (ISSN: 0938-7994, 1432-1084electronic, 0938-7994linking), 2000; 10(12): 1894-1898.
Impact Factor: 1.119
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Salvatore M, Del Vecchio S
Dynamic imaging: Scintimammography (383 views)
Eur J Radiol Elsevier Sci Ireland Ltd (ISSN: 0720-048x), 1998 May; 27(SUPPL.2): S259-S259.
Impact Factor: 0.537
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Maurea S, Cuocolo A, Reynolds JC, Neumann RD, Salvatore M
Diagnostic imaging in patients with paragangliomas. Computer tomography, magnetic resonance and MIBG scintigraphy comparison (316 views)
Q J Nucl Med (ISSN: 1124-3937, 1125-0135), 1996; 40(4): 365-371.
Impact Factor: 2.125
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Maurea S, Lastoria S, Klain M, Brunetti A, Boscaino A, Lupoli G, Salvatore M
Diagnostic evaluation of thyroid involvement by histiocytosis (296 views)
J Nucl Med (ISSN: 0161-5505, 1535-5667, 1535-5667electronic), 1994 Feb; 35(2): 263-265.
Impact Factor: 3.491
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* Investigating plasma volume expanders as novel macromolecular MRI-CEST contrast agents for tumor contrast-enhanced imaging (20 views)
Magn Reson Med (ISSN: 0740-3194linking, 1522-2594electronic), 2021 Aug; 86(2): 995-1007.
Impact Factor: 3.635
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Stanzione A, Maurea S, Danzi R, Cuocolo R, Galatola R, Romeo V, Raffone A, Travaglino A, Di Spiezio Sardo A, Insabato L, Pace L, Scaglione M, Brunetti A, Mainenti PP
* MRI to assess deep myometrial invasion in patients with endometrial cancer: A multi-reader study to evaluate the diagnostic role of different sequences (17 views)
Eur J Radiol (ISSN: 0720-048xlinking), 2021 May; 138: 109629-109629.
Impact Factor: 2.687
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Zöllner FG, Dastrù W, Irrera P, Longo DL, Bennett KM, Beeman SC, Bretthorst GL, Garbow JR
* Analysis Protocol for Dynamic Contrast Enhanced (DCE) MRI of Renal Perfusion and Filtration (19 views)
Methods Mol Biol (ISSN: 1064-3745linking, 1940-6029electronic), 2021; 2216: 637-653.
Impact Factor: 1.17
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Kim H, Wu Y, Villano D, Longo DL, Mcmahon MT, Sun PZ
* Analysis Protocol for the Quantification of Renal pH Using Chemical Exchange Saturation Transfer (CEST) MRI (23 views)
Methods Mol Biol (ISSN: 1064-3745linking, 1940-6029electronic), 2021; 2216: 667-688.
Impact Factor: 1.17
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Irrera P, Consolino L, Dastrù W, Pedersen M, Zöllner FG, Longo DL
* Dynamic Contrast Enhanced (DCE) MRI-Derived Renal Perfusion and Filtration: Experimental Protocol (16 views)
Methods Mol Biol (ISSN: 1064-3745linking, 1940-6029electronic), 2021; 2216: 429-441.
Impact Factor: 1.17
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Pedersen M, Irrera P, Dastrù W, Zöllner FG, Bennett KM, Beeman SC, Bretthorst GL, Garbow JR, Longo DL
* Dynamic Contrast Enhancement (DCE) MRI-Derived Renal Perfusion and Filtration: Basic Concepts (28 views)
Methods Mol Biol (ISSN: 1064-3745linking, 1940-6029electronic), 2021; 2216: 205-227.
Impact Factor: 1.17
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Longo DL, Irrera P, Consolino L, Sun PZ, Mcmahon MT
* Renal pH Imaging Using Chemical Exchange Saturation Transfer (CEST) MRI: Basic Concept (39 views)
Methods Mol Biol (ISSN: 1064-3745linking, 1940-6029electronic), 2021; 2216: 241-256.
Impact Factor: 1.17
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Pavuluri KD, Consolino L, Longo DL, Irrera P, Sun PZ, Mcmahon MT
* Renal pH Mapping Using Chemical Exchange Saturation Transfer (CEST) MRI: Experimental Protocol (11 views)
Methods Mol Biol (ISSN: 1064-3745linking, 1940-6029electronic), 2021; 2216: 455-471.
Impact Factor: 1.17
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Tear LR, Carrera C, Gianolio E, Aime S
* Towards an Improved Design of MRI Contrast Agents: Synthesis and Relaxometric Characterisation of Gd-HPDO3A Analogues (74 views)
Chemistry (ISSN: 0947-6539linking, 1521-3765electronic), 2020 May 12; 26(27): 6056-6063.
Impact Factor: 4.857
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Monti S, Paganelli C, Buizza G, Preda L, Valvo F, Baroni G, Palma G, Cella L
* A novel framework for spatial normalization of dose distributions in voxel-based analyses of brain irradiation outcomes (48 views)
Phys Med (ISSN: 1120-1797linking), 2020 Jan; 69: 164-169.
Impact Factor: 2.485
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Camera L, Pezzullo F, Acampora A, Liuzzi R, Rispo A, Nardone OM, Luglio G, Bucci L, Castiglione F, Brunetti A
* Multi-detector CT enterography in active inflammatory bowel disease: Image quality and diagnostic efficacy of a low-radiation high contrast protocol (117 views)
Clin Imaging (ISSN: 0899-7071linking, 1873-4499), 2019 Nov; 58: 27-33.
Impact Factor: 0.658
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Granato L, Longo D, Boutry S, Vander Elst L, Henoumont C, Aime S, Muller RN, Laurent S
* Synthesis and Relaxometric Characterization of New Poly[N, N-bis(3-aminopropyl)glycine] (PAPGly) Dendrons Gd-Based Contrast Agents and Their in Vivo Study by Using the Dynamic Contrast-Enhanced MRI Technique at Low Field (1 T) (135 views)
Chem Biodivers (ISSN: 1612-1872linking), 2019 Nov; 16(11): e1900322-e1900322.
Impact Factor: 1.449
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Romeo V, Sarno L, Volpe A, Ginocchio MI, Esposito R, Mainenti PP, Petretta M, Liuzzi R, D'Armiento M, Martinelli P, Brunetti A, Maurea S
* US and MR imaging findings to detect placental adhesion spectrum (PAS) in patients with placenta previa: a comparative systematic study (97 views)
Abdom Radiol (ISSN: 2366-0058electronic, 2366-004xprint), 2019 Oct; 44(10): 3398-3407.
Impact Factor: 2.147
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Greco A, Ragucci M, Liuzzi R, Prota M, Cocchia N, Fatone G, Mancini M, Brunetti A, Meomartino L
* Noninvasive Ultrasound Monitoring of Embryonic and Fetal Development in Chinchilla lanigera to Predict Gestational Age: Preliminary Evaluation of This Species as a Novel Animal Model of Human Pregnancy (196 views)
Contrast Media Mol Imaging (ISSN: 1555-4309linking, 1555-4317electronic), 2019 May 27; 2019: 6319476-6319476.
Impact Factor: 4.02
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Cocozza S, Pontillo G, Lanzillo R, Russo C, Petracca M, Di Stasi M, Paolella C, Vola EA, Criscuolo C, Moccia M, Lamberti A, Monti S, Brescia Morra V, Elefante A, Palma G, Tedeschi E, Brunetti A
* MRI features suggestive of gadolinium retention do not correlate with Expanded Disability Status Scale worsening in Multiple Sclerosis (283 views)
Neuroradiology (ISSN: 0028-3940linking, 1432-1920electronic), 2019 Feb; 61(2): 155-162.
Impact Factor: 1.287
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Romeo V, Maurea S, Cuocolo R, Petretta M, Mainenti PP, Verde F, Coppola M, Dell'Aversana S, Brunetti A
* Characterization of Adrenal Lesions on Unenhanced MRI Using Texture Analysis: A Machine-Learning Approach (195 views)
J Magn Reson Imaging (ISSN: 1522-2586electronic, 1053-1807linking), 2018 Jul; 48(1): 198-204.
Impact Factor: 1.302
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Tedeschi E, Cocozza S, Borrelli P, Ugga L, Morra VB, Palma G
* Longitudinal assessment of dentate nuclei relaxometry during massive gadobutrol exposure (312 views)
Magn Reson Med Sci (ISSN: 1347-3182), 2018; 17(1): 100-104.
Impact Factor: 0
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Gianolio E, Bardini P, Arena F, Stefania R, Di Gregorio E, Iani R, Aime S
* Gadolinium Retention in the Rat Brain: Assessment of the Amounts of Insoluble Gadolinium-containing Species and Intact Gadolinium Complexes after Repeated Administration of Gadolinium-based Contrast Agents (320 views)
Radiology (ISSN: 0033-8419, 1527-1315), 2017 Dec; 285(3): 839-849.
Impact Factor: 7.469
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Longo DL, Aime S
* A generalized ratiometric chemical exchange saturation transfer (CEST) MRI approach for mapping renal pH using iopamidol (229 views)
Magn Reson Med (ISSN: 0740-3194, 1522-2594electronic, 0740-3194linking), 2017 Jul 07; 79(3): 1553-1558.
Impact Factor: 4.082
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Filippi M, Catanzaro V, Patrucco D, Botta M, Tei L, Terreno E
* First in vivo MRI study on theranostic dendrimersomes (280 views)
J Control Release (ISSN: 0168-3659), 2017 Feb 28; 248: 45-52.
Impact Factor: 7.877
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Imbriaco M, De LucaS, Coppola M, Fusari M, Klain M, Puglia M, Mainenti P, Liuzzi R, Maurea S
* Diagnostic Accuracy of Gd-EOB-DTPA for Detection Hepatocellular Carcinoma (HCC): A Comparative Study with Dynamic Contrast Enhanced Magnetic Resonance Imaging (MRI) and Dynamic Contrast Enhanced Computed Tomography (CT) (253 views)
Pol J Radiol (ISSN: 1733-134xprint, 1733-134xlinking, 1899-0967electronic), 2017 Feb 01; 82: 50-57.
Impact Factor: 0.567
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Anemone A, Consolino L, Longo DL
* MRI-CEST assessment of tumour perfusion using X-ray iodinated agents: comparison with a conventional Gd-based agent (211 views)
Eur Radiol (ISSN: 0938-7994, 1432-1084electronic, 0938-7994linking), 2017; 27(5): 2170-2179.
Impact Factor: 4.027
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Consolino L, Longo DL, Sciortino M, Dastru W, Cabodi S, Giovenzana GB, Aime S
* Assessing tumor vascularization as a potential biomarker of imatinib resistance in gastrointestinal stromal tumors by dynamic contrast-enhanced magnetic resonance imaging (263 views)
Gastric Cancer (ISSN: 1436-3291, 1436-3291linking), 2016 Dec 19; 20(4): 629-639.
Impact Factor: 5.454
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Filippi M, Boido M, Pasquino C, Garello F, Boffa C, Terreno E
* Successful in vivo MRI tracking of MSCs labeled with Gadoteridol in a Spinal Cord Injury experimental model (279 views)
Exp Neurol (ISSN: 0014-4886), 2016 Aug; 282: 66-77.
Impact Factor: 4.706
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Ferrauto G, Delli Castelli D, Di Gregorio E, Terreno E, Aime S
* LipoCEST and cellCEST imaging agents: opportunities and challenges (363 views)
Wires Nanomed Nanobi (ISSN: 1939-5116), 2016 Jul; 8(4): 602-618.
Impact Factor: 4.761
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Tedeschi E, Palma G, Canna A, Cocozza S, Russo C, Borrelli P, Lanzillo R, Angelini V, Postiglione E, Morra VB, Salvatore M, Brunetti A, Quarantelli M
* In vivo dentate nucleus MRI relaxometry correlates with previous administration of Gadolinium-based contrast agents (455 views)
Eur Radiol (ISSN: 0938-7994, 1432-1084electronic, 0938-7994linking), 2016 Feb 23; 26(12): 4577-4584.
Impact Factor: 3.967
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Camera L, Romano F, Liccardo I, Liuzzi R, Imbriaco M, Mainenti PP, Pizzuti LM, Segreto S, Maurea S, Brunetti A
* Balancing Radiation and Contrast Media Dose in Single-Pass Abdominal Multidetector CT: Prospective Evaluation of Image Quality (380 views)
Acad Radiol (ISSN: 1076-6332, 1878-4046electronic, 1076-6332linking), 2015 Nov; 22(11): 1419-1426.
Impact Factor: 1.966
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Loewe C, Arnaiz J, Krause D, Marti-bonmati L, Haneder S, Kramer U, Dalia Study Group , Lell M, Lonjedo E, Tartaro A, Aschauer M, Burrel M, Lombardi M, Izzillo R, Mainenti PP, Heautot JF, Leicher-düber A, Krug B, Arteaga C
* MR Angiography at 3 T of Peripheral Arterial Disease: A Randomized Prospective Comparison of Gadoterate Meglumine and Gadobutrol (284 views)
Am J Roentgenol (ISSN: 0361-803x), 2015 Jun; 204(6): 1311-1321.
Impact Factor: 2.66
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Longo DL, Sun PZ, Consolino L, Michelotti FC, Uggeri F, Aime S
* A general MRI-CEST ratiometric approach for pH imaging: demonstration of in vivo pH mapping with iobitridol (418 views)
J Am Chem Soc (ISSN: 0002-7863, 0002-2786, 0002-7863print), 2014 Oct 15; 136(41): 14333-14336.
Impact Factor: 12.113
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Maurea S, Mainenti PP, Tambasco A, Imbriaco M, Mollica C, Laccetti E, Camera L, Liuzzi R, Salvatore M
* Diagnostic accuracy of MR imaging to identify and characterize focal liver lesions: comparison between gadolinium and superparamagnetic iron oxide contrast media (292 views)
Quant Imaging Med Surg (ISSN: 2223-4292, 2223-4292print, 2223-4306linking), 2014 Jun; 4(3): 181-189.
Impact Factor: 3.105
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Camera L, Sagnelli M, Guadagno P, Mainenti PP, Marra T, Scotto di Santolo M, Fei L, Salvatore M
* Colonic perforation by a transmural and transvalvular migrated retained sponge: Multi-detector computed tomography findings (358 views)
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Impact Factor: 2.369
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Iodice D, Di Donato O, Liccardo I, Lamanna L, Segreto S, Salvatore M, Imbriaco M
* Prevalence of extramammary findings on breast MRI: a large retrospective single-centre study (380 views)
Radiol Med (ISSN: 1826-6983, 0033-8362, 1826-6983electronic), 2013 Oct; 118(7): 1109-1118.
Impact Factor: 1.368
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Mancini M, Greco A, Salvatore G, Liuzzi R, Di Maro G, Vergara E, Chiappetta G, Pasquinelli R, Brunetti A, Salvatore M
* Imaging of thyroid tumor angiogenesis with microbubbles targeted to vascular endothelial growth factor receptor type 2 in mice (485 views)
Bmc Med Imaging (ISSN: 1471-2342, 1471-2342electronic), 2013 Sep 12; 13(1): 31-31.
Impact Factor: 0.983
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Ruggiero D, Paolillo S, Ratta GD, Mariniello A, Formisano T, Pellegrino AM, Filardi PP
* [Endothelial function as a marker of pre-clinical atherosclerosis: assessment techniques and clinical implications] (340 views)
Monaldi Arch Chest Dis Card Ser (ISSN: 1122-0643, 1122-0643print), 2013 Sep; 80(3): 106-110.
Impact Factor: 7.132
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Mancini M, Di Donato O, Saldalamacchia G, Liuzzi R, Rivellese A, Salvatore M
* Contrast-enhanced ultrasound evaluation of peripheral microcirculation in diabetic patients: effects of cigarette smoking (441 views)
Radiol Med (ISSN: 1826-6983, 0033-8362, 1826-6983electronic), 2013 Mar; 118(2): 206-214.
Impact Factor: 1.368
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Mainenti PP, Iodice D, Cozzolino I, Segreto S, Capece S, Sica G, Magliulo M, Ciancia G, Pace L, Salvatore M
* Tomographic imaging of the spleen: the role of morphological and metabolic features in differentiating benign from malignant diseases (296 views)
Clin Imaging (ISSN: 1873-4499, 0899-7071, 0899-7071linking), 2012 Sep; 36(5): 559-567.
Impact Factor: 0.648
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Mancini M, Morra VB, Di Donato O, Maglio V, Lanzillo R, Liuzzi R, Salvatore E, Brunetti A, Iaccarino V, Salvatore M
* Multiple sclerosis: cerebral circulation time (419 views)
Radiology (ISSN: 1527-1315, 0033-8419, 1527-1315electronic), 2012 Mar; 262(3): 947-955.
Impact Factor: 6.339
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Menchise V, Digilio G, Gianolio E, Cittadino E, Catanzaro V, Carrera C, Aime S
* MR Contrast Agents (335 views)
Mol Pharm (ISSN: 1543-8384), 2011 Sep; 8(5): 1750-1756.
Impact Factor: 4.782
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Terreno E, Boffa C, Menchise V, Fedeli F, Carrera C, Castelli DD, Digilio G, Aime S
* Gadolinium-doped LipoCEST agents: A potential novel class of dual 1H-MRI probes (345 views)
Chem Commun (ISSN: 1359-7345, 1364-548x, 1364-548xelectronic), 2011 Apr 28; 47(16): 4667-4669.
Impact Factor: 6.169
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Accardo A, Morisco A, Tesauro D, Pedone C, Morelli G
* Naposomes: A new class of peptide-derivatized, target-selective multimodal nanoparticles for imaging and therapeutic applications (409 views)
Ther Deliv (ISSN: 2041-5990), 2011 Feb; 2(2): 235-257.
Impact Factor: 0
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Casciaro S, Conversano F, Ragusa A, Malvindi MA, Franchini R, Greco A, Pellegrino T, Gigli G
* Optimal enhancement configuration of silica nanoparticles for ultrasound imaging and automatic detection at conventional diagnostic frequencies (403 views)
Invest Radiol (ISSN: 0020-9996, 1536-0210, 1536-0210electronic), 2010 Nov; 45(11): 715-724.
Impact Factor: 4.67
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Maurea S, Mollica C, Imbriaco M, Fusari M, Camera L, Salvatore M
* Magnetic resonance cholangiography with mangafodipir trisodium in Caroli's disease with pancreas involvement (391 views)
Jop (ISSN: 1590-8577, 1590-0857), 2010 Sep 06; 11(5): 460-463.
Impact Factor: 0
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Digilio G, Menchise V, Gianolio E, Catanzaro V, Carrera C, Napolitano R, Fedeli F, Aime S
* Exofacial protein thiols as a route for the internalization of Gd(III)-based complexes for magnetic resonance imaging cell labeling (455 views)
J Med Chem (ISSN: 0022-2623, 1520-4804, 0022-2623print), 2010 Jul 8; 53(13): 4877-4890.
Impact Factor: 5.207
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Lanzillo R, Orefice G, Quarantelli M, Rinaldi C, Prinster A, Ventrella G, Spitaleri D, Lus G, Vacca G, Carotenuto B, Salvatore E, Brunetti A, Tedeschi G, Brescia Morra V
* Atorvastatin combined to interferon to verify the efficacy (ACTIVE) in relapsing-remitting active multiple sclerosis patients: A longitudinal controlled trial of combination therapy (561 views)
Mult Scler (ISSN: 1352-4585, 1477-0970, 1352-4585linking), 2010 Apr; 16(4): 450-454.
Impact Factor: 4.23
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Digilio G, Catanzaro V, Fedeli F, Gianolio E, Menchise V, Napolitano R, Gringeri C, Aime S
* Targeting exofacial protein thiols with Gd-III complexes. An efficient procedure for MRI cell labelling (345 views)
Chem Commun (ISSN: 1359-7345, 1364-548x, 1364-548xelectronic), 2009 Feb 28; (8): 893-895.
Impact Factor: 5.504
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Lapi F, Cecchi E, Pedone C, Attanasio F, Banchelli G, Vannacci A, Di Pirro M, Moschini M, Berni V, Matucci R, Cini E, Scalia A, Tendi E, Mugelli A
* Safety aspects of iodinated contrast media related to their physicochemical properties: A pharmacoepidemiology study in two Tuscany hospitals (494 views)
Eur J Clin Pharmacol Springer Verlag (ISSN: 0031-6970, 1432-1041), 2008 Jul; 64(7): 723-737.
Impact Factor: 2.497
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Ragozzino A, Lassandro F, De Ritis R, Imbriaco M
* Value of MRI in three patients with major vascular injuries after laparoscopic cholecystectomy (250 views)
Emergency Radiology (ISSN: 1070-3004), 2007 Nov; 14(6): 443-447.
Impact Factor: 6.214
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Berkouk K, Quarantelli M, Prinster A, Landeau B, Alfano B, Baron JC
* Mapping The Relative Contribution Of Gray Matter Activity Versus Volume In Brain Pet. A New Approach (390 views) (PDF 231 views)
J Neuroimaging (ISSN: 1051-2284, 1051-2284linking), 2006 Jul; 16(3): 224-235.
Impact Factor: 1.298
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Imbriaco M, Smeraldo D, Liuzzi R, Carrillo F, Cacace G, Vecchione D, Diglio A, Salvatore M
* Multislice CT with single-phase technique in patients with suspected pancreatic cancer (245 views)
Radiol Med (ISSN: 0033-8362, 1826-6983, 1826-6983electronic), 2006 Mar; 111(2): 159-166.
Impact Factor: 1.368
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Cuocolo A, Acampa W, Imbriaco M, De Luca N, Iovino GL, Salvatore M
* The many ways to myocardial perfusion imaging (478 views)
Q J Nucl Med Mol Im (ISSN: 1824-4785, 1824-4478, 1824-4785linking), 2005 Mar; 49(1): 4-18.
Impact Factor: 1.724
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Cirillo LC, Camera L, Della Noce M, Castiglione F, Mazzacca G, Salvatore M
Accuracy of enteroclysis in Crohn's disease of the small bowel: A retrospective study (472 views)
Eur Radiol (ISSN: 0938-7994, 1432-1084electronic, 0938-7994linking), 2000; 10(12): 1894-1898.
Impact Factor: 1.119
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Salvatore M, Del Vecchio S
Dynamic imaging: Scintimammography (383 views)
Eur J Radiol Elsevier Sci Ireland Ltd (ISSN: 0720-048x), 1998 May; 27(SUPPL.2): S259-S259.
Impact Factor: 0.537
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Maurea S, Cuocolo A, Reynolds JC, Neumann RD, Salvatore M
Diagnostic imaging in patients with paragangliomas. Computer tomography, magnetic resonance and MIBG scintigraphy comparison (316 views)
Q J Nucl Med (ISSN: 1124-3937, 1125-0135), 1996; 40(4): 365-371.
Impact Factor: 2.125
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Maurea S, Lastoria S, Klain M, Brunetti A, Boscaino A, Lupoli G, Salvatore M
Diagnostic evaluation of thyroid involvement by histiocytosis (296 views)
J Nucl Med (ISSN: 0161-5505, 1535-5667, 1535-5667electronic), 1994 Feb; 35(2): 263-265.
Impact Factor: 3.491
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54 Records (53 excluding Abstracts).
Total impact factor: 165.443 (164.906 excluding Abstracts).
Total 5 year impact factor: 192.929 (190.81 excluding Abstracts).
Total impact factor: 165.443 (164.906 excluding Abstracts).
Total 5 year impact factor: 192.929 (190.81 excluding Abstracts).
322 views. Last view on Thursday 27 April 2023, 9:15:10
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