Evaluation of vascular changes with optical coherence tomography angiography after ruthenium-106 brachytherapy of circumscribed choroidal hemangioma(270 views) Cennamo G, Rossi C, Breve MA, Velotti N, Farella A, Liuzzi R, Cennamo G
Eye Clinic, Department of Public Health, University of Naples Federico II, Naples, Italy. xgilda@hotmail.com.
Department of Neurosciences, Reproductive Sciences and Dentistry, University of Naples Federico II, Naples, Italy.
Department of Advanced Biomedical Sciences, University of Naples Federico II, Naples, Italy.
Functional and Morphologic Department of Radiotherapy and Legal Medicine, University of Naples "Federico II", Naples, Italy.
Institute of Biostructure and Bioimaging, National Research Council (CNR), Naples, Italy.
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Evaluation of vascular changes with optical coherence tomography angiography after ruthenium-106 brachytherapy of circumscribed choroidal hemangioma
PURPOSE:
To describe the vascular changes of
circumscribed choroidal hemangioma (CCH) after ruthenium-106
brachytherapy using optical coherence tomography angiography
(angio-OCT).
METHODS:
Seven eyes of 7 patients diagnosed
with symptomatic CCH who underwent ruthenium-106 plaque radiotherapy
were included in the study. Patients underwent complete ophthalmic
examination, bulbar echography and angio-OCT. The same protocol was
applied 1 year after ruthenium-106 brachytherapy.
RESULTS:
At
baseline, the mean best-corrected visual acuity (BCVA) in affected eyes
was 0.67 ± 0.14 logMAR, and the mean tumor thickness was 4.46 ± 0.91 mm
measured by standardized A-scan echography. After ruthenium-106 plaque
treatment, the mean BCVA increased to 0.17 ± 0.10 logMAR (p = 0.001) and
the mean tumor thickness to 2.29 ± 0.71 mm (p = 0.003). Moreover, there
was a significant reduction of the tumor basal diameter (p= 0.009).
Intra-tumor angio-OCT measurements revealed a statistically significant
reduction of the vessel and flow areas (p = 0.006 and p = 0.002,
respectively) 1 year after brachytherapy.
CONCLUSIONS:
Angio-OCT
is a non-invasive reliable method with which to evaluate the vascular
features of CCH and consequently to monitor changes after conservative
treatment.
Evaluation of vascular changes with optical coherence tomography angiography after ruthenium-106 brachytherapy of circumscribed choroidal hemangioma
No results.
Evaluation of vascular changes with optical coherence tomography angiography after ruthenium-106 brachytherapy of circumscribed choroidal hemangioma