Exploring structural properties of potent human carbonic anhydrase inhibitors bearing a 4-(cycloalkylamino-1-carbonyl)benzenesulfonamide moiety(327 views) Buemi MR, Di Fiore A, De Luca L, Angeli A, Mancuso F, Ferro S, Monti SM, Buonanno M, Russo E, De Sarro G, De Simone G, Supuran CT, Gitto R
Eur J Med Chem (ISSN: 1768-3254electronic, 0223-5234linking), 2019 Feb 1; 163: 443-452.
Keywords: Benzenesulfonamides, Ca Inhibitors, Carbonic Anhydrases, X-Ray Crystallography, Carbonic Anhydrase Ii Antagonists, Carbonic Anhydrase Inhibitors Chemical Synthesis Chemistry, Carbonic Anhydrases Drug Effects, Catalytic Domain, Drug Design, Humans, Molecular Structure, Protein Binding, Protein Isoforms Metabolism, Sulfonamides Chemical Synthesis Chemistry,
Affiliations: *** IBB - CNR ***
Dipartimento di Scienze Chimiche, Biologiche, Farmaceutiche ed Ambientali (CHIBIOFARAM), Universita degli Studi di Messina, Viale Palatucci, Polo didattico SS, Annunziata, 98168, Messina, Italy., Istituto di Biostrutture e Bioimmagini-CNR, Via Mezzocannone 16, 80134, Napoli, Italy., Dipartimento NEUROFARBA, Universita di Firenze, Via Ugo Schiff 6, 50019, Sesto Fiorentino, Italy., Pharmacology Chair, Dept. of Science of Health School of Medicine, University of Catanzaro, Campus Universitario "Salvatore Venuta", Viale Europa - Loc. Germaneto, 88100, Catanzaro, Italy., Dipartimento di Scienze Chimiche, Biologiche, Farmaceutiche ed Ambientali (CHIBIOFARAM), Universita degli Studi di Messina, Viale Palatucci, Polo didattico SS, Annunziata, 98168, Messina, Italy. Electronic address: rgitto@unime.it.,
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Exploring structural properties of potent human carbonic anhydrase inhibitors bearing a 4-(cycloalkylamino-1-carbonyl)benzenesulfonamide moiety