Changes, functional disorders, and diseases in the gastrointestinal tract of elderly(404 views) Durazzo M, Campion D, Fagoonee S, Pellicano R, Sonne JU, Erckenbrecht JF, Grassi M, Petraccia L, Mennuni G, Fontana M, Scarno A, Sabetta S, Fraioli A
Keywords: Age Distribution, Age Factors, 80 And Over, Digestive System Surgical Procedures, Endoscopy, Gastrointestinal, Female, Gastrointestinal Agents, Adverse Effects, Therapeutic Use, Gastrointestinal Diseases, Diagnosis, Epidemiology, Physiopathology, Helicobacter Infections, Complications, Drug Therapy, Humans, Meta-Analysis As Topic, Middle Aged, Morbidity, Trends, Population Dynamics, Prevalence, Methods, Dyspepsia, Geriatric Assessment, Physiology, Digestive System Diseases, Gastrointestinal Motility, Gastrointestinal Tract, Growth, Development,
Affiliations: *** IBB - CNR ***
Department of Medical Sciences, University of Turin, Turin, Italy - marilena.durazzo@unito.it., Department of Gastroenterology, Citta della Salute e della Scienza di Torino, University of Turin, Turin, Italy., Molecular Biotechnology Center, Institute for Biostructures and Bioimages, National Research Council, University of Turin, Turin, Italy., Unit of Gastroenterology, Molinette Hospital, Citta della Salute e della Scienza di Torino, Turin, Italy., Klinik fur Innere Medizin mit Gastroenterologie und Onkologie, Florence-Nigthtingale-Krankenhaus, Kaiserswerther Diakonie, Dusseldorf, Deutschland, sonne@kaiserswerther-diakonie.de., Deparment Internal Medicine and Medical Disciplines, Unit of Internal Medicine E, Medical Therapy and Thermal Medicine, School of Specialization in Thermal Medicine, Rome, Italy.,
References: Not available.
Changes, functional disorders, and diseases in the gastrointestinal tract of elderly
This article describes changes in the basic digestive functions (motility, secretion, intraluminal digestion, absorption) that occur during aging. Elderly individuals frequently have oropharyngeal muscle dysmotility and altered swallowing of food. Reductions in esophageal peristalsis and lower esophageal sphincter (LES) pressures are also more common in the aged and may cause gastroesophageal reflux. Gastric motility and emptying and small bowel motility are generally normal in elderly subjects, although delayed motility and gastric emptying have been reported in some cases. The propulsive motility of the colon is also decreased, and this alteration is associated with neurological and endocrine-paracrine changes in the colonic wall. Decreased gastric secretions (acid, pepsin) and impairment of the mucous-bicarbonate barrier are frequently described in the elderly and may lead to gastric ulcer. Exocrine pancreatic secretion is often decreased, as is the bile salt content of bile. These changes represent the underlying mechanisms of symptomatic gastrointestinal dysfunctions in the elderly, such as dysphagia, gastroesophageal reflux disease, primary dyspepsia, irritable bowel syndrome, primary constipation, maldigestion, and reduced absorption of nutrients. Therapeutic management of these conditions is also described. The authors also review the gastrointestinal diseases that are more common in the elderly, such as atrophic gastritis, gastric ulcer, colon diverticulosis, malignant tumors, gallstones, chronic hepatitis, liver cirrhosis, Hepato Cellular Carcinoma (HCC), and chronic pancreatitis.
Changes, functional disorders, and diseases in the gastrointestinal tract of elderly
No results.
Changes, functional disorders, and diseases in the gastrointestinal tract of elderly
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