Carnosine and Cognitive Deficits
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Carnosine and Cognitive Deficits
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211 views
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Bellia F, Vecchio G, Rizzarelli E
Diet And Nutr In Dement And Cogn Decline (ISSN: 9780-1240793979780124078246)
,
2014;
N/D: 973-982.
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Paper type:
Book Chapter,
Impact factor:
0,
5-year impact factor:
0
Url:
https://www.scopus.com/inward/record.uri?eid=2-s2.0-84943251679&doi=10.1016%2fB978-0-12-407824-6.00090-2&partnerID=40&md5=a168190281bb84f2855b182edc29ab3b
Keywords:
Antioxidant, Brain, Carnosinase, Carnosine Derivatives, Metal Chelator, Neurodegeneration, Nitrosative Stress, Oxidative Stress,
Affiliations:
*** IBB - CNR ***
Institute of Biostructure and Bioimaging, Catania, Italy
University of Catania, Catania, Italy
References:
Not available.
Carnosine and Cognitive Deficits
Carnosine (β-alanyl- l-histidine) is a natural dipeptide widely and abundantly distributed in excitable tissues of several animals. Although its physiological role has not been completely understood yet, many beneficial actions have been attributed to carnosine, such as being an antioxidant, antiglycating and ion-chelating agent, a wound-healing promoter, and a free-radical scavenger. The neuroprotection of carnosine in cognitive deficits caused by oxidative stress-driven disorders has been reviewed. The effects of carnosine have been extensively studied both in vivo and in vitro models of cerebral damages, such as neurodegenerative disorders and hypoxia-ischemia injuries. Beside the classical sacrificial agent, carnosine has been reevaluated as a molecular chaperone and an inducer of antioxidant systems in oxidative stress conditions. Thus, beneficial effects on most of the common biochemical events that characterize cognitive deficits make carnosine a very promising molecule among all the endogenous compounds in the treatment and/or prevention of oxidative-driven diseases. © 2015 Elsevier Inc. All rights reserved.
Carnosine and Cognitive Deficits
▼
Targeting Of Protein-Protein Interactions For Therapeutic Purposes
Ruvo Menotti
Sandomenico Annamaria
Doti Nunzianna
▼
Environmental chemistry & human health. Computational studies. Synthesis of small molecules, modified peptides and nucleobase-decorated peptides. Spectroscopic and computational investigation on the potential of natural products in biomedicine. Nucleic acid and protein binding studies
Musumeci Domenica
Vicidomini Caterina
Palumbo Rosanna
Roviello Giovanni Nicola
▼
Characterization of neurotoxic and neuroprotective factors by using computational methodologies
Vitagliano Luigi
Esposito Luciana
▼
New peptide–based molecules as NGF mimetics in the therapy of neurological dysfunctions
Del Gatto Annarita
Zaccaro Laura
Carnosine and Cognitive Deficits
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Cipriano L, Minino R, Liparoti M, Polverino A, Romano A, Bonavita S,
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Grasso GI, Bellia F, Arena G, Satriano C, Vecchio G, Rizzarelli E
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Grasso G, Santoro AM, Lanza V, Sbardella D, Tundo GR, Ciaccio C, Marini S, Coletta M, Milardi D
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Caraci F, Bruno V, Copani A, Matrisciano F, Nicoletti F, Battaglia G
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, Rosa LD, Vigliotti C, Cataldi M
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Oliveri V, Bellia F, Grasso GI, Pietropaolo A, Vecchio G
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Trehalose-8-hydroxyquinoline conjugates as antioxidant modulators of Aβ aggregation
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Oliveri V, Bellia F, Vecchio G
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Cyclodextrin 3-functionalized with 8-hydroxyquinoline as an antioxidant inhibitor of metal-induced amyloid aggregation
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Oliveri V, Grasso GI, Bellia F, Attanasio F, Viale M, Vecchio G
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Bellia F, Rizzarelli E, Vecchio G
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The chemistry of carnosine derivatives
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2015;
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Oliveri V, Bellia F, Pietropaolo A, Vecchio G
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Unusual Cyclodextrin Derivatives as a New Avenue to Modulate Self- and Metal-Induced Aβ Aggregation
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Oliveri V, Attanasio F, Puglisi A, Spencer J, Sgarlata C, Vecchio G
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Salvatore E,
Tedeschi E
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Mollica C
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Grasso GI, Arena G, Bellia F, Rizzarelli E, Vecchio G
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Dathan NA,
Alterio V
, Troiano E, Vullo D, Ludwig M,
De Simone G
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Biochemical Characterization Of The Chloroplastic β-Carbonic Anhydrase From Flaveria Bidentis (l. ) "kuntze"
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Russo GL, Russo M, Spagnuolo C, Tedesco I, Bilotto S, Iannitti R,
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Bellia F, Oliveri V, Rizzarelli E, Vecchio G
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New derivative of carnosine for nanoparticle assemblies
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Tedesco I, Russo M, Bilotto S, Spagnuolo C, Scognamiglio A,
Palumbo R
, Nappo A, Iacomino G, Moio L, Russo GL
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Caraci F, Battaglia G, Sortino MA, Spampinato S, Molinaro G, Copani A, Nicoletti F, Bruno V
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Metabotropic glutamate receptors in neurodegeneration/neuroprotection: Still a hot topic?
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Bellia F, Vecchio G, Rizzarelli E
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Carnosine derivatives: new multifunctional drug-like molecules
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Calabrese V, Cornelius C, Dinkova-Kostova AT, Iavicoli I, Di Paola R, Koverech A, Cuzzocrea S, Rizzarelli E, Calabrese EJ
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De Rosa V
, Erkekoǧlu P, Forestier A, Favier A, Hincal F, Diamond AM, Douki T, Rachidi W
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Low doses of selenium specifically stimulate the repair of oxidative DNA damage in LNCaP prostate cancer cells
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Arena G, Fattorusso R, Grasso G, Grasso GI, Isernia C, Malgieri G, Milardi D, Rizzarelli E
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Zinc(II) complexes of ubiquitin: speciation, affinity and binding features
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2011 Oct 4;
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Bellia F, Vecchio G, Cuzzocrea S, Calabrese V, Rizzarelli E
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Neuroprotective features of carnosine in oxidative driven diseases
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Lanza V, Bellia F, D'Agata R, Grasso G, Rizzarelli E, Vecchio G
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Limauro D,
D'Ambrosio K
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Langella E
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De Simone G
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Erkekoǧlu P, Rachidi W,
De Rosa V
, Giray B, Favier A, Hincal F
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Pedone E
, Limauro D, Bartolucci S
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Erratum: The machinery for oxidative protein folding in thermophiles (Antioxidants and Redox Signaling (2008) 10 (157-169))
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Bellia F, Calabrese V, Guarino F, Cavallaro M, Cornelius C, De Pinto V, Rizzarelli E
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Carnosinase levels in aging brain: redox state induction and cellular stress response
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Calabrese V, Cornelius C, Rizzarelli E, Owen JB, Dinkova-Kostova AT, Butterfield DA
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La Mendola D, Pietropaolo A, Pappalardo G, Zannoni C, Rizzarelli E
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2009 Jun;
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Calabrese V, Cornelius C, Mancuso C, Barone E, Calafato S, Bates T, Rizzarelli E, Kostova AT
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Calabrese V, Cornelius C, Mancuso C, Pennisi G, Calafato S, Bellia F, Bates TE, Giuffrida Stella AM, Schapira T, Dinkova Kostova AT, Rizzarelli E
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2008 Dec;
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La Mendola D, Pietropaolo A, Pappalardo G, Zannoni C, Rizzarelli E
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Prion proteins leading to neurodegeneration
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Current Alzheimer Research (ISSN: 1567-2050)
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2008 Dec;
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Caraci F, Busceti C, Biagioni F, Aronica E, Mastroiacovo F, Cappuccio I, Battaglia G, Bruno V, Caricasole A, Copani A, Nicoletti
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The Wnt antagonist, Dickkopf-1, as a target for the treatment of neurodegenerative disorders
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Esposito L
, Seydel A, Aiello R, Sorrentino G, Cendron L, Zanotti G, Zagari
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The crystal structure of the superoxide dismutase from Helicobacter pylori reveals a structured C-terminal extension
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494 views
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Bba-Gen Subjects (ISSN: 1570-9639, 0006-3002, 0925-4439)
,
2008 Nov;
1784(11): 1601-1606.
Impact Factor:
2.233
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Gustavsson T, Banyasz A, Sarkar N, Markovitsi D,
Improta R
*
Statin: New life for an old drug
(
430 views
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Pharmacol Res Academic Press
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2008 Jun 23;
350(1-3): 1-2.
Impact Factor:
3.976
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Limauro D,
Pedone E
, Galdi I, Bartolucci S
*
Peroxiredoxins as cellular guardians in Sulfolobus solfataricus - characterization of Bcp1, Bcp3 and Bcp4
(
459 views
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Febs Journal (ISSN: 1742-464x)
,
2008 May;
275(9): 2067-2077.
Impact Factor:
3.139
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Bellia F, Amorini AM, La Mendola D, Vecchio G, Tavazzi B, Giardina B, Di Pietro V, Lazzarino G, Rizzarelli E
*
New glycosidic derivatives of histidine-containing dipeptides with antioxidant properties and resistant to carnosinase activity
(
649 views
)
Eur J Med Chem (ISSN: 0223-5234, 1768-3254, 1768-3254electronic)
,
2008 Feb;
43(2): 373-380.
Impact Factor:
2.882
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Copani A, Guccione S, Giurato L, Caraci F, Calafiore M, Sortino MA
*
The cell cycle molecules behind neurodegeneration in Alzheimer's disease: Perspectives for drug development
(
542 views
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Curr Med Chem (ISSN: 0929-8673, 1875-533x, 1875-533xelectronic)
,
2008;
15(24): 2420-2432.
Impact Factor:
4.823
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Calabrese V, Mancuso C, Calvani M, Rizzarelli E, Butterfield DA, Stella AM
*
Nitric oxide in the central nervous system: neuroprotection versus neurotoxicity
(
1216 views
)
Nature Reviews Neuroscience (ISSN: 1471-0048)
,
2007 Oct;
8(10): 766-775.
Impact Factor:
24.52
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Amorini AM, Bellia F, Di Pietro V, Giardina B, La Mendola D, Lazzarino G, Sortino S, Tavazzi B, Rizzarelli E, Vecchio G
*
Synthesis And Antioxidant Activity Of New Homocarnosine Beta-Cyclodextrin Conjugates
(
488 views
)
Eur J Med Chem (ISSN: 0223-5234, 1768-3254, 1768-3254electronic)
,
2007 Jul;
42(7): 910-920.
Impact Factor:
2.301
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Bellia F, La Mendola D, Maccarrone G, Mineo P, Vitalini D, Scamporrino E, Sortino S, Vecchio G, Rizzarelli E
*
Copper(II) Complexes With Beta-Cyclodextrin-Homocarnosine Conjugates And Their Antioxidant Activity
(
378 views
)
Inorg Chim Acta (ISSN: 0020-1693)
,
2007 Feb 15;
360(3): 945-954.
Impact Factor:
1.713
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Calabrese V, Colombrita C, Guagliano E, Sapienza M, Ravagna A, Cardile V, Scapagnini G, Santoro AM, Mangiameli A, Butterfield DA, Giuffrida Stella AM, Rizzarelli E
*
Protective effect of carnosine during nitrosative stress in astroglial cell cultures
(
837 views
)
Neurochemical Research (ISSN: 0364-3190, 1573-6903)
,
2005 Jun;
30(6-7): 797-807.
Impact Factor:
2.187
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Tedesco I, Nappo A, Petitto F, Iacomino G, Nazzaro F,
Palumbo R
, Russo Gian L
*
Antioxidant and cytotoxic properties of lyophilized beer extracts on HL-60 cell line
(
882 views
)
Nutr Cancer (ISSN: 0163-5581)
,
2005;
52(1): 74-83.
Impact Factor:
2.426
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Russo M, Tedesco I, Iacomino G,
Palumbo R
, Galano G, Russo GL
*
Dietary phytochemicals in chemoprevention of cancer
(
430 views
)
Curr Med Chem (ISSN: 1568-0134)
,
2005;
5(1): 61-72.
Impact Factor:
3.715
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Caridi A, Cufari A, Lovino R,
Palumbo R
, Tedesco I
*
Influence of Yeast on Polyphenol Composition of Wine
(
326 views
)
Food Technol Biotechnol (ISSN: 1330-9862)
,
2004 Jan;
42(1): 37-40.
Impact Factor:
0.475
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Russo M,
Palumbo R
, Mupo A, Tosto M, Iacomino G, Scognamiglio A, Tedesco I, Galano G, Russo GL
*
Flavonoid quercetin sensitizes a CD95-resistant cell line to apoptosis by activating protein kinase Cα
(
732 views
)
Oncogene (ISSN: 0950-9232, 1476-5594)
,
2003;
22(21): 3330-3342.
Impact Factor:
6.495
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Bonomo RP, Bruno V, Conte E, De Guidi G, La Mendola D, Maccarrone G, Nicoletti F, Rizzarelli E, Sortino S, Vecchio G
*
Potentiometric, spectroscopic and antioxidant activity studies of SOD mimics containing carnosine
(
449 views
)
Dalton T (ISSN: 1477-9226, 1477-9234, 1477-9234electronic)
,
2003;
(23): 4406-4415.
Impact Factor:
2.908
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Borrelli RC, Fogliano V,
Monti SM
, Ames JM
*
Characterization of melanoidins from a glucose-glycine model system
(
293 views
)
Eur Food Res Technol (ISSN: 1438-2377)
,
2002 Sep;
215(3): 210-215.
Impact Factor:
1.021
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La Mendola D, Sortino S, Rizzarelli E, Vecchiog
*
Synthesis Of New Carnosine Derivatives Of R-Cyclodextrin And Their Hydroxyl Radical Scavanger Ability
(
448 views
)
Helvetica Chimica Acta
,
2002;
85: 1633-1643.
Impact Factor:
1.394
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Tedesco I, Russo GL, Nazzaro F, Russo M,
Palumbo R
*
Antioxidant effect of red wine anthocyanins in normal and catalase-inactive human erythrocytes
(
1326 views
)
J Nutr Biochem (ISSN: 0955-2863)
,
2001 Sep;
12(9): 505-511.
Impact Factor:
1.039
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Monti SM
, Ritieni A, Sacchi R, Skog K, Borgen E, Fogliano V
*
Characterization of phenolic compounds in virgin olive oil and their effect on the formation of carcinogenic/mutagenic heterocyclic amines in a model system
(
816 views
)
J Agric Food Chem (ISSN: 0021-8561)
,
2001 Sep;
49(8): 3969-3975.
Impact Factor:
1.576
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Tedesco I, Russo M, Russo P, Iacomino G, Russo GL, Carraturo A, Faruolo C, Moio L,
Palumbo R
Antioxidant effect of red wine polyphenols on red blood cells
(
763 views
)
J Nutr Biochem (ISSN: 0955-2863)
,
2000 Feb;
11(2): 114-119.
Impact Factor:
1.083
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Monti SM
, Borrelli RC, Ritieni A, Fogliano V
A comparison of color formation and Maillard reaction products of a lactose-lysine and lactose-N(α)-acetyllysine model system
(
696 views
)
J Agric Food Chem (ISSN: 0021-8561)
,
2000;
48(4): 1041-1046.
Impact Factor:
1.56
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Fogliano V, Ritieni A,
Monti SM
, Gallo M, Della Medaglia D, Ambrosino ML, Sacchi R
Antioxidant activity of virgin olive oil phenolic compounds in a micellar system
(
378 views
)
Journal Of The Science Of Food And Agriculture (ISSN: 0022-5142)
,
1999 Oct;
79(13): 1803-1808.
Impact Factor:
1.097
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Wink DA, Vodovotz Y, Grisham MB, DeGraff W, Cook JC,
Pacelli R
, Krishna M, Mitchell JB
Antioxidant effects of nitric oxide
(
395 views
)
Method Enzymol (ISSN: 0076-6879, 1557-7988electronic)
,
1998;
301: 413-424.
Impact Factor:
2.823
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Wink DA, Cook JA,
Pacelli R
, DeGraff W, Gamson J, Liebmann J, Krishna MC, Mitchell JB
The effect of various nitric oxide-donor agents on hydrogen peroxide-mediated toxicity: A direct correlation between nitric oxide formation and protection
(
865 views
)
Arch Bioch Bioph (ISSN: 0003-9861, 0003-9861linking)
,
1996 Jul 15;
331(2): 241-248.
Impact Factor:
2.649
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Wink DA, Grisham MB, Miles AM, Nims RW, Krishna MC,
Pacelli R
, Teague D, Poore CM, Cook JA, Ford PC
Determination of selectivity of reactive nitrogen oxide species for various substrates
(
465 views
)
Method Enzymol (ISSN: 0076-6879, 1557-7988electronic, 0076-6879linking)
,
1996;
268: 120-130.
Impact Factor:
2.435
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Bonomo RP, De Flora A, Rizzarelli E, Santoro AM, Tabbì G, Tonetti M
Copper(II) complexes encapsulated in human red blood cells
(
657 views
)
J Chem Res (ISSN: 0162-0134, 1873-3344, 0162-0134print)
,
1995 Sep;
59(4): 773-784.
Impact Factor:
1.342
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Costanzo LL, De Guidi G, Giuffrida S, Sortino S, Condorelli G, Pappalardo G
Antioxidant effect of copper(II) on photosensitized lipid peroxidation
(
661 views
)
J Chem Res (ISSN: 0162-0134print, 0162-0134linking, 1873-3344)
,
1995 Feb;
57(2): 115-125.
Impact Factor:
1.342
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73
Records (
71
excluding Abstracts).
Total impact factor:
290.277
(
283.964
excluding Abstracts).
Total 5 year impact factor:
287.15
(
279.77
excluding Abstracts).
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