Carnosine and Cognitive Deficits (171 views)
Diet And Nutr In Dement And Cogn Decline (ISSN: 9780-1240793979780124078246), 2014; N/D: 973-982.
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Paper type: Book Chapter,
Impact factor: 0, 5-year impact factor: 0
Url: https://www.scopus.com/inward/record.uri?eid=2-s2.0-84943251679&doi=10.1016%2fB978-0-12-407824-6.00090-2&partnerID=40&md5=a168190281bb84f2855b182edc29ab3b
Keywords: Antioxidant, Brain, Carnosinase, Carnosine Derivatives, Metal Chelator, Neurodegeneration, Nitrosative Stress, Oxidative Stress,
Affiliations:
*** IBB - CNR ***
Institute of Biostructure and Bioimaging, Catania, Italy
University of Catania, Catania, Italy
References:
Crush, K.G., Carnosine and related substances in animal tissues (1970) Comp Bio Chem Physiol, 34, pp. 3-3
Abe, H., Role of histidine-related compounds as intracellular proton buffering constituents in vertebrate muscle (2000) Biochemistry (Mosc), 65, pp. 757-765
Gulewitsch, W., Amiradzibi, S., Ueber das Carnosin, eine neue organische Base des Fleischextractes (1900) Ber Deut Chem Ges, 33, pp. 1902-1903
Hipkiss, A.R., Carnosine and its possible roles in nutrition and health (2009) Adv Food Nutr Res, 57, pp. 87-154
Drozak, J., Veiga-da-Cunha, M., Vertommen, D., Stroobant, V., Van Schaftingen, E., Molecular identification of carnosine synthase as ATP-grasp domain-containing protein 1 (ATPGD1) (2010) J Biol Chem, 285, pp. 9346-9356
Bauer, K., Hallermayer, K., Salnikow, J., Kleinkauf, H., Hamprecht, B., Biosynthesis of carnosine and related peptides by glial cells in primary culture (1982) J Biol Chem, 257, pp. 3593-3597
Harding, J.W., O'Fallon, J.V., The subcellular distribution of carnosine, carnosine synthetase, and carnosinase in mouse olfactory tissues (1979) Brain Res, 173, pp. 99-109
Bauer, K., Carnosine and homocarnosine, the forgotten, enigmatic peptides of the brain (2005) Neurochem Res, 30, pp. 1339-1345
Dieck, S.T., Heuer, H., Ehrchen, J., Otto, C., Bauer, K., The peptide transporter PepT2 is expressed in rat brain and mediates the accumulation of the fluorescent dipeptide derivative beta-Ala-Lys-Nepsilon-AMCA in astrocytes (1999) Glia, 25, pp. 10-20
Bakardjiev, A., Bauer, K., Biosynthesis, release, and uptake of carnosine in primary cultures (2000) Biochemistry (Mosc), 65, pp. 779-782
Xiang, J., Hu, Y., Smith, D.E., Keep, R.F., PEPT2-mediated transport of 5-aminolevulinic acid and carnosine in astrocytes (2006) Brain Res, 1122, pp. 18-23
Saito, H., Terada, T., Okuda, M., Sasaki, S., Inui, K., Molecular cloning and tissue distribution of rat peptide transporter PEPT2 (1996) Biochim Biophys Acta, 1280, pp. 173-177
Bonfanti, L., Peretto, P., De Marchis, S., Fasolo, A., Carnosine-related dipeptides in the mammalian brain (1999) Prog Neurobiol, 59, pp. 333-353
De Marchis, S., Modena, C., Peretto, P., Migheli, A., Margolis, F.L., Fasolo, A., Carnosine-related dipeptides in neurons and glia (2000) Biochemistry (Mosc), 65, pp. 824-833
Teufel, M., Saudek, V., Ledig, J.-P., Bernhardt, A., Boularand, S., Carreau, A., Sequence identification and characterization of human carnosinase and a closely related non-specific dipeptidase (2003) J Biol Chem, 278, pp. 6521-6531
Bellia, F., Calabrese, V., Guarino, F., Cavallaro, M., Cornelius, C., De Pinto, V., Carnosinase levels in aging brain: redox state induction and cellular stress response (2009) Antioxid Redox Signal, 11, pp. 2759-2775
Otani, H., Okumura, N., Hashida-Okumura, A., Nagai, K., Identification and characterization of a mouse dipeptidase that hydrolyzes l-carnosine (2005) J Biochem (Tokyo), 137, pp. 167-175
Bossy-Wetzel, E., Schwarzenbacher, R., Lipton, S.A., Molecular pathways to neurodegeneration (2004) Nat Med, 10, pp. S2-S9
Preston, J.E., Hipkiss, A.R., Himsworth, D.T., Romero, I.A., Abbott, J.N., Toxic effects of beta-amyloid(25-35) on immortalised rat brain endothelial cell: protection by carnosine, homocarnosine and beta-alanine (1998) Neurosci Lett, 242, pp. 105-108
Boldyrev, A., Koudinov, A., Berezov, T., Carpenter, D.O., Amyloid-beta induced cell death is independent of free radicals (2004) J Alzheimers Dis, 6, pp. 633-638. , discussion 673-681
Fu, Q., Dai, H., Hu, W., Fan, Y., Shen, Y., Zhang, W., Carnosine protects against Abeta42-induced neurotoxicity in differentiated rat PC12 cells (2008) Cell Mol Neurobiol, 28, pp. 307-316
Attanasio, F., Convertino, M., Magno, A., Caflisch, A., Corazza, A., Haridas, H., Carnosine inhibits Abeta(42) aggregation by perturbing the H-bond network in and around the central hydrophobic cluster (2013) Chem Bio Chem, 14, pp. 583-592
Fonteh, A.N., Harrington, R.J., Tsai, A., Liao, P., Harrington, M.G., Free amino acid and dipeptide changes in the body fluids from Alzheimer's disease subjects (2007) Amino Acids, 32, pp. 213-224
Corona, C., Frazzini, V., Silvestri, E., Lattanzio, R., La Sorda, R., Piantelli, M., Effects of dietary supplementation of carnosine on mitochondrial dysfunction, amyloid pathology, and cognitive deficits in 3xTg-AD mice (2011) PLoS One, 6, p. e17971
Kawahara, M., Koyama, H., Nagata, T., Sadakane, Y., Zinc, copper, and carnosine attenuate neurotoxicity of prion fragment PrP106-126 (2011) Metallomics, 3, pp. 726-734
Boldyrev, A., Fedorova, T., Stepanova, M., Dobrotvorskaya, I., Kozlova, E., Boldanova, N., Carnosine increases efficiency of DOPA therapy of Parkinson's disease: a pilot study (2008) Rejuvenation Res, 11, pp. 821-827
Kang, J.H., Kim, K.S., Enhanced oligomerization of the alpha-synuclein mutant by the Cu, Zn-superoxide dismutase and hydrogen peroxide system (2003) Mol Cells, 15, pp. 87-93
Calabrese, V., Mancuso, C., Calvani, M., Rizzarelli, E., Butterfield, D.A., Stella, A.M., Nitric oxide in the central nervous system: neuroprotection versus neurotoxicity (2007) Nat Rev Neurosci, 8, pp. 766-775
Calabrese, V., Colombrita, C., Guagliano, E., Sapienza, M., Ravagna, A., Cardile, V., Protective effect of carnosine during nitrosative stress in astroglial cell cultures (2005) Neurochem Res, 30, pp. 797-807
Spina-Purrello, V., Giliberto, S., Barresi, V., Nicoletti, V.G., Giuffrida Stella, A.M., Rizzarelli, E., Modulation of PARP-1 and PARP-2 expression by l-carnosine and trehalose after LPS and INFgamma-induced oxidative stress (2010) Neurochem Res, 35, pp. 2144-2153
Nicoletti, V.G., Santoro, A.M., Grasso, G., Vagliasindi, L.I., Giuffrida, M.L., Cuppari, C., Carnosine interaction with nitric oxide and astroglial cell protection (2007) J Neurosci Res, 85, pp. 2239-2245
Milardi, D., Rizzarelli, E., (2011) Neurodegeneration metallostasis and proteostasis, , Royal Society of Chemistry, Cambridge
Bush, A.I., Pettingell, W.H., Multhaup, G., Paradis, D.M., Vonsattel, J.P., Gusella, J.F., Rapid induction of Alzheimer A beta amyloid formation by zinc (1994) Science, 265, pp. 1464-1467
Arena, G., La Mendola, D., Pappalardo, G., Sóvágó, I., Rizzarelli, E., Interactions of Cu2+ with prion family peptide fragments: considerations on affinity, speciation and coordination (2012) Coord Chem Rev, 256, pp. 2202-2218
Sensi, S.L., Rapposelli, I.G., Frazzini, V., Mascetra, N., Altered oxidant-mediated intraneuronal zinc mobilization in a triple transgenic mouse model of Alzheimer's disease (2008) Exp Gerontol, 43, pp. 488-492
Matsukura, T., Tanaka, H., Applicability of zinc complex of l-carnosine for medical use (2000) Biochemistry (Mosc), 65, pp. 817-823
Ohata, S., Moriyama, C., Yamashita, A., Nishida, T., Kusumoto, C., Mochida, S., Polaprezinc protects mice against endotoxin shock (2010) J Clin Biochem Nutr, 46, pp. 234-243
Kalmar, B., Greensmith, L., Induction of heat shock proteins for protection against oxidative stress (2009) Adv Drug Del Rev, 61, pp. 310-318
Sale, C., Saunders, B., Harris, R.C., Effect of beta-alanine supplementation on muscle carnosine concentrations and exercise performance (2010) Amino Acids, 39, pp. 321-333
Derave, W., Everaert, I., Beeckman, S., Baguet, A., Muscle carnosine metabolism and beta-alanine supplementation in relation to exercise and training (2010) Sports Med, 40, pp. 247-263
Bellia, F., Vecchio, G., Rizzarelli, E., Carnosine derivatives: new multifunctional drug-like molecules (2012) Amino Acids, 43, pp. 153-163
Vistoli, G., Orioli, M., Pedretti, A., Regazzoni, L., Canevotti, R., Negrisoli, G., Design, synthesis, and evaluation of carnosine derivatives as selective and efficient sequestering agents of cytotoxic reactive carbonyl species (2009) Chem Med Chem, 4, pp. 967-975
Di Paola, R., Impellizzeri, D., Salinaro, A.T., Mazzon, E., Bellia, F., Cavallaro, M., Administration of carnosine in the treatment of acute spinal cord injury (2011) Biochem Pharmacol, 82, pp. 1478-1489
Grasso, G.I., Arena, G., Bellia, F., Maccarrone, G., Parrinello, M., Pietropaolo, A., Intramolecular weak interactions in the thermodynamic stereo-selectivity of copper(II) complexes with carnosine-trehalose conjugates (2011) Chemistry, 17, pp. 9448-9455
Grasso, G.I., Bellia, F., Arena, G., Vecchio, G., Rizzarelli, E., Noncovalent interaction-driven stereoselectivity of copper(II) complexes with cyclodextrin derivatives of l-and d-carnosine (2011) Inorg Chem, 50, pp. 4917-4924
Orioli, M., Vistoli, G., Regazzoni, L., Pedretti, A., Lapolla, A., Rossoni, G., Design, synthesis, ADME properties, and pharmacological activities of beta-alanyl-d-histidine (d-carnosine) prodrugs with improved bioavailability (2011) Chem Med Chem, 6, pp. 1269-1282
Lipton, P., Ischemic cell death in brain neurons (1999) Physiol Rev, 79, pp. 1431-1568
Tabakman, R., Lazarovici, P., Kohen, R., Neuroprotective effects of carnosine and homocarnosine on pheochromocytoma PC12 cells exposed to ischemia (2002) J Neurosci Res, 68, pp. 463-469
Zhang, X., Song, L., Cheng, X., Yang, Y., Luan, B., Jia, L., Carnosine pretreatment protects against hypoxia-ischemia brain damage in the neonatal rat model (2011) Eur J Pharmacol, 667, pp. 202-207
Harris, R.C., Hultman, E., Nordesjo, L.O., Glycogen, glycolytic intermediates and high energy phosphates determined in biopsy samples of musculus quadriceps femoris in man at rest. Methods and variance of values (1974) Scand J Clin Lab Invest, 33, pp. 109-120
Baguet, A., Bourgois, J., Vanhee, L., Achten, E., Derave, W., Important role of carnosine in rowing performance (2010) J Appl Physiol, 109, pp. 1096-1101
Everaert, I., Mooyaart, A., Baguet, A., Zutinic, A., Baelde, H., Achten, E., Vegetarianism, female gender and increasing age, but not CNDP1 genotype, are associated with reduced muscle carnosine levels in humans (2011) Amino Acids, 40, pp. 1221-1229
Babizhayev, M.A., Yegorov, Y.E., Advanced drug delivery of N-acetylcarnosine (N-acetyl-beta-alanyl-l-histidine), carcinine (beta-alanylhistamine) and l-carnosine (beta-alanyl-l-histidine) in targeting peptide compounds as pharmacological chaperones for use in tissue engineering, human disease management and therapy: from in vitro to the clinic (2010) Recent Pat Drug Deliv Formul, 4, pp. 198-230
Calabrese, V., Cornelius, C., Mancuso, C., Pennisi, G., Calafato, S., Bellia, F., Cellular stress response: a novel target for chemoprevention and nutritional neuroprotection in aging, neurodegenerative disorders and longevity (2008) Neurochem Res, 33, pp. 2444-2471
Diet And Nutr In Dement And Cogn Decline (ISSN: 9780-1240793979780124078246), 2014; N/D: 973-982.
Export to BibTeX Export to EndNote
Paper type: Book Chapter,
Impact factor: 0, 5-year impact factor: 0
Url: https://www.scopus.com/inward/record.uri?eid=2-s2.0-84943251679&doi=10.1016%2fB978-0-12-407824-6.00090-2&partnerID=40&md5=a168190281bb84f2855b182edc29ab3b
Keywords: Antioxidant, Brain, Carnosinase, Carnosine Derivatives, Metal Chelator, Neurodegeneration, Nitrosative Stress, Oxidative Stress,
Affiliations:
*** IBB - CNR ***
Institute of Biostructure and Bioimaging, Catania, Italy
University of Catania, Catania, Italy
References:
Crush, K.G., Carnosine and related substances in animal tissues (1970) Comp Bio Chem Physiol, 34, pp. 3-3
Abe, H., Role of histidine-related compounds as intracellular proton buffering constituents in vertebrate muscle (2000) Biochemistry (Mosc), 65, pp. 757-765
Gulewitsch, W., Amiradzibi, S., Ueber das Carnosin, eine neue organische Base des Fleischextractes (1900) Ber Deut Chem Ges, 33, pp. 1902-1903
Hipkiss, A.R., Carnosine and its possible roles in nutrition and health (2009) Adv Food Nutr Res, 57, pp. 87-154
Drozak, J., Veiga-da-Cunha, M., Vertommen, D., Stroobant, V., Van Schaftingen, E., Molecular identification of carnosine synthase as ATP-grasp domain-containing protein 1 (ATPGD1) (2010) J Biol Chem, 285, pp. 9346-9356
Bauer, K., Hallermayer, K., Salnikow, J., Kleinkauf, H., Hamprecht, B., Biosynthesis of carnosine and related peptides by glial cells in primary culture (1982) J Biol Chem, 257, pp. 3593-3597
Harding, J.W., O'Fallon, J.V., The subcellular distribution of carnosine, carnosine synthetase, and carnosinase in mouse olfactory tissues (1979) Brain Res, 173, pp. 99-109
Bauer, K., Carnosine and homocarnosine, the forgotten, enigmatic peptides of the brain (2005) Neurochem Res, 30, pp. 1339-1345
Dieck, S.T., Heuer, H., Ehrchen, J., Otto, C., Bauer, K., The peptide transporter PepT2 is expressed in rat brain and mediates the accumulation of the fluorescent dipeptide derivative beta-Ala-Lys-Nepsilon-AMCA in astrocytes (1999) Glia, 25, pp. 10-20
Bakardjiev, A., Bauer, K., Biosynthesis, release, and uptake of carnosine in primary cultures (2000) Biochemistry (Mosc), 65, pp. 779-782
Xiang, J., Hu, Y., Smith, D.E., Keep, R.F., PEPT2-mediated transport of 5-aminolevulinic acid and carnosine in astrocytes (2006) Brain Res, 1122, pp. 18-23
Saito, H., Terada, T., Okuda, M., Sasaki, S., Inui, K., Molecular cloning and tissue distribution of rat peptide transporter PEPT2 (1996) Biochim Biophys Acta, 1280, pp. 173-177
Bonfanti, L., Peretto, P., De Marchis, S., Fasolo, A., Carnosine-related dipeptides in the mammalian brain (1999) Prog Neurobiol, 59, pp. 333-353
De Marchis, S., Modena, C., Peretto, P., Migheli, A., Margolis, F.L., Fasolo, A., Carnosine-related dipeptides in neurons and glia (2000) Biochemistry (Mosc), 65, pp. 824-833
Teufel, M., Saudek, V., Ledig, J.-P., Bernhardt, A., Boularand, S., Carreau, A., Sequence identification and characterization of human carnosinase and a closely related non-specific dipeptidase (2003) J Biol Chem, 278, pp. 6521-6531
Bellia, F., Calabrese, V., Guarino, F., Cavallaro, M., Cornelius, C., De Pinto, V., Carnosinase levels in aging brain: redox state induction and cellular stress response (2009) Antioxid Redox Signal, 11, pp. 2759-2775
Otani, H., Okumura, N., Hashida-Okumura, A., Nagai, K., Identification and characterization of a mouse dipeptidase that hydrolyzes l-carnosine (2005) J Biochem (Tokyo), 137, pp. 167-175
Bossy-Wetzel, E., Schwarzenbacher, R., Lipton, S.A., Molecular pathways to neurodegeneration (2004) Nat Med, 10, pp. S2-S9
Preston, J.E., Hipkiss, A.R., Himsworth, D.T., Romero, I.A., Abbott, J.N., Toxic effects of beta-amyloid(25-35) on immortalised rat brain endothelial cell: protection by carnosine, homocarnosine and beta-alanine (1998) Neurosci Lett, 242, pp. 105-108
Boldyrev, A., Koudinov, A., Berezov, T., Carpenter, D.O., Amyloid-beta induced cell death is independent of free radicals (2004) J Alzheimers Dis, 6, pp. 633-638. , discussion 673-681
Fu, Q., Dai, H., Hu, W., Fan, Y., Shen, Y., Zhang, W., Carnosine protects against Abeta42-induced neurotoxicity in differentiated rat PC12 cells (2008) Cell Mol Neurobiol, 28, pp. 307-316
Attanasio, F., Convertino, M., Magno, A., Caflisch, A., Corazza, A., Haridas, H., Carnosine inhibits Abeta(42) aggregation by perturbing the H-bond network in and around the central hydrophobic cluster (2013) Chem Bio Chem, 14, pp. 583-592
Fonteh, A.N., Harrington, R.J., Tsai, A., Liao, P., Harrington, M.G., Free amino acid and dipeptide changes in the body fluids from Alzheimer's disease subjects (2007) Amino Acids, 32, pp. 213-224
Corona, C., Frazzini, V., Silvestri, E., Lattanzio, R., La Sorda, R., Piantelli, M., Effects of dietary supplementation of carnosine on mitochondrial dysfunction, amyloid pathology, and cognitive deficits in 3xTg-AD mice (2011) PLoS One, 6, p. e17971
Kawahara, M., Koyama, H., Nagata, T., Sadakane, Y., Zinc, copper, and carnosine attenuate neurotoxicity of prion fragment PrP106-126 (2011) Metallomics, 3, pp. 726-734
Boldyrev, A., Fedorova, T., Stepanova, M., Dobrotvorskaya, I., Kozlova, E., Boldanova, N., Carnosine increases efficiency of DOPA therapy of Parkinson's disease: a pilot study (2008) Rejuvenation Res, 11, pp. 821-827
Kang, J.H., Kim, K.S., Enhanced oligomerization of the alpha-synuclein mutant by the Cu, Zn-superoxide dismutase and hydrogen peroxide system (2003) Mol Cells, 15, pp. 87-93
Calabrese, V., Mancuso, C., Calvani, M., Rizzarelli, E., Butterfield, D.A., Stella, A.M., Nitric oxide in the central nervous system: neuroprotection versus neurotoxicity (2007) Nat Rev Neurosci, 8, pp. 766-775
Calabrese, V., Colombrita, C., Guagliano, E., Sapienza, M., Ravagna, A., Cardile, V., Protective effect of carnosine during nitrosative stress in astroglial cell cultures (2005) Neurochem Res, 30, pp. 797-807
Spina-Purrello, V., Giliberto, S., Barresi, V., Nicoletti, V.G., Giuffrida Stella, A.M., Rizzarelli, E., Modulation of PARP-1 and PARP-2 expression by l-carnosine and trehalose after LPS and INFgamma-induced oxidative stress (2010) Neurochem Res, 35, pp. 2144-2153
Nicoletti, V.G., Santoro, A.M., Grasso, G., Vagliasindi, L.I., Giuffrida, M.L., Cuppari, C., Carnosine interaction with nitric oxide and astroglial cell protection (2007) J Neurosci Res, 85, pp. 2239-2245
Milardi, D., Rizzarelli, E., (2011) Neurodegeneration metallostasis and proteostasis, , Royal Society of Chemistry, Cambridge
Bush, A.I., Pettingell, W.H., Multhaup, G., Paradis, D.M., Vonsattel, J.P., Gusella, J.F., Rapid induction of Alzheimer A beta amyloid formation by zinc (1994) Science, 265, pp. 1464-1467
Arena, G., La Mendola, D., Pappalardo, G., Sóvágó, I., Rizzarelli, E., Interactions of Cu2+ with prion family peptide fragments: considerations on affinity, speciation and coordination (2012) Coord Chem Rev, 256, pp. 2202-2218
Sensi, S.L., Rapposelli, I.G., Frazzini, V., Mascetra, N., Altered oxidant-mediated intraneuronal zinc mobilization in a triple transgenic mouse model of Alzheimer's disease (2008) Exp Gerontol, 43, pp. 488-492
Matsukura, T., Tanaka, H., Applicability of zinc complex of l-carnosine for medical use (2000) Biochemistry (Mosc), 65, pp. 817-823
Ohata, S., Moriyama, C., Yamashita, A., Nishida, T., Kusumoto, C., Mochida, S., Polaprezinc protects mice against endotoxin shock (2010) J Clin Biochem Nutr, 46, pp. 234-243
Kalmar, B., Greensmith, L., Induction of heat shock proteins for protection against oxidative stress (2009) Adv Drug Del Rev, 61, pp. 310-318
Sale, C., Saunders, B., Harris, R.C., Effect of beta-alanine supplementation on muscle carnosine concentrations and exercise performance (2010) Amino Acids, 39, pp. 321-333
Derave, W., Everaert, I., Beeckman, S., Baguet, A., Muscle carnosine metabolism and beta-alanine supplementation in relation to exercise and training (2010) Sports Med, 40, pp. 247-263
Bellia, F., Vecchio, G., Rizzarelli, E., Carnosine derivatives: new multifunctional drug-like molecules (2012) Amino Acids, 43, pp. 153-163
Vistoli, G., Orioli, M., Pedretti, A., Regazzoni, L., Canevotti, R., Negrisoli, G., Design, synthesis, and evaluation of carnosine derivatives as selective and efficient sequestering agents of cytotoxic reactive carbonyl species (2009) Chem Med Chem, 4, pp. 967-975
Di Paola, R., Impellizzeri, D., Salinaro, A.T., Mazzon, E., Bellia, F., Cavallaro, M., Administration of carnosine in the treatment of acute spinal cord injury (2011) Biochem Pharmacol, 82, pp. 1478-1489
Grasso, G.I., Arena, G., Bellia, F., Maccarrone, G., Parrinello, M., Pietropaolo, A., Intramolecular weak interactions in the thermodynamic stereo-selectivity of copper(II) complexes with carnosine-trehalose conjugates (2011) Chemistry, 17, pp. 9448-9455
Grasso, G.I., Bellia, F., Arena, G., Vecchio, G., Rizzarelli, E., Noncovalent interaction-driven stereoselectivity of copper(II) complexes with cyclodextrin derivatives of l-and d-carnosine (2011) Inorg Chem, 50, pp. 4917-4924
Orioli, M., Vistoli, G., Regazzoni, L., Pedretti, A., Lapolla, A., Rossoni, G., Design, synthesis, ADME properties, and pharmacological activities of beta-alanyl-d-histidine (d-carnosine) prodrugs with improved bioavailability (2011) Chem Med Chem, 6, pp. 1269-1282
Lipton, P., Ischemic cell death in brain neurons (1999) Physiol Rev, 79, pp. 1431-1568
Tabakman, R., Lazarovici, P., Kohen, R., Neuroprotective effects of carnosine and homocarnosine on pheochromocytoma PC12 cells exposed to ischemia (2002) J Neurosci Res, 68, pp. 463-469
Zhang, X., Song, L., Cheng, X., Yang, Y., Luan, B., Jia, L., Carnosine pretreatment protects against hypoxia-ischemia brain damage in the neonatal rat model (2011) Eur J Pharmacol, 667, pp. 202-207
Harris, R.C., Hultman, E., Nordesjo, L.O., Glycogen, glycolytic intermediates and high energy phosphates determined in biopsy samples of musculus quadriceps femoris in man at rest. Methods and variance of values (1974) Scand J Clin Lab Invest, 33, pp. 109-120
Baguet, A., Bourgois, J., Vanhee, L., Achten, E., Derave, W., Important role of carnosine in rowing performance (2010) J Appl Physiol, 109, pp. 1096-1101
Everaert, I., Mooyaart, A., Baguet, A., Zutinic, A., Baelde, H., Achten, E., Vegetarianism, female gender and increasing age, but not CNDP1 genotype, are associated with reduced muscle carnosine levels in humans (2011) Amino Acids, 40, pp. 1221-1229
Babizhayev, M.A., Yegorov, Y.E., Advanced drug delivery of N-acetylcarnosine (N-acetyl-beta-alanyl-l-histidine), carcinine (beta-alanylhistamine) and l-carnosine (beta-alanyl-l-histidine) in targeting peptide compounds as pharmacological chaperones for use in tissue engineering, human disease management and therapy: from in vitro to the clinic (2010) Recent Pat Drug Deliv Formul, 4, pp. 198-230
Calabrese, V., Cornelius, C., Mancuso, C., Pennisi, G., Calafato, S., Bellia, F., Cellular stress response: a novel target for chemoprevention and nutritional neuroprotection in aging, neurodegenerative disorders and longevity (2008) Neurochem Res, 33, pp. 2444-2471
Carnosine and Cognitive Deficits
Carnosine (β-alanyl- l-histidine) is a natural dipeptide widely and abundantly distributed in excitable tissues of several animals. Although its physiological role has not been completely understood yet, many beneficial actions have been attributed to carnosine, such as being an antioxidant, antiglycating and ion-chelating agent, a wound-healing promoter, and a free-radical scavenger. The neuroprotection of carnosine in cognitive deficits caused by oxidative stress-driven disorders has been reviewed. The effects of carnosine have been extensively studied both in vivo and in vitro models of cerebral damages, such as neurodegenerative disorders and hypoxia-ischemia injuries. Beside the classical sacrificial agent, carnosine has been reevaluated as a molecular chaperone and an inducer of antioxidant systems in oxidative stress conditions. Thus, beneficial effects on most of the common biochemical events that characterize cognitive deficits make carnosine a very promising molecule among all the endogenous compounds in the treatment and/or prevention of oxidative-driven diseases. © 2015 Elsevier Inc. All rights reserved.
Carnosine (β-alanyl- l-histidine) is a natural dipeptide widely and abundantly distributed in excitable tissues of several animals. Although its physiological role has not been completely understood yet, many beneficial actions have been attributed to carnosine, such as being an antioxidant, antiglycating and ion-chelating agent, a wound-healing promoter, and a free-radical scavenger. The neuroprotection of carnosine in cognitive deficits caused by oxidative stress-driven disorders has been reviewed. The effects of carnosine have been extensively studied both in vivo and in vitro models of cerebral damages, such as neurodegenerative disorders and hypoxia-ischemia injuries. Beside the classical sacrificial agent, carnosine has been reevaluated as a molecular chaperone and an inducer of antioxidant systems in oxidative stress conditions. Thus, beneficial effects on most of the common biochemical events that characterize cognitive deficits make carnosine a very promising molecule among all the endogenous compounds in the treatment and/or prevention of oxidative-driven diseases. © 2015 Elsevier Inc. All rights reserved.
Carnosine and Cognitive Deficits
Carnosine and Cognitive Deficits
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Rendina A, Drongitis D, Donizetti A, Fucci L, Milan G, Tripodi F, Giustezza F, Postiglione A, Pappata S, Ferrari R, Bossù P, Angiolillo A, Di Costanzo A, Caiazzo M, Vitale E
* CD33 and SIGLECL1 Immunoglobulin Superfamily Involved in Dementia (94 views)
J Neuropathol Exp Neurol (ISSN: 0022-3069linking), 2020 Jul 10; 79(8): 891-901.
Impact Factor: 3.51
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Dubbioso R, Ruggiero L, Esposito M, Tarantino P, De Angelis M, Aruta F, Pappata S, Ugga L, Piperno A, Iorio R, Santoro L, Iodice R, Manganelli F
* Different cortical excitability profiles in hereditary brain iron and copper accumulation (131 views)
Neurol Sci (ISSN: 1590-1874linking, 1590-3478), 2020 Mar; 41(3): 679-685.
Impact Factor: 1.315
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Spampinato SF, Copani A, Nicoletti F, Sortino MA, Caraci F
* Metabotropic Glutamate Receptors in Glial Cells: A New Potential Target for Neuroprotection? (231 views)
Front Mol Neurosci (ISSN: 1662-5099, 1662-5099linking, 1662-5099electronic), 2018 Nov 13; 11: 414-414.
Impact Factor: 3.902
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Falanga A, Mercurio FA, Siciliano A, Lombardi L, Galdiero S, Guida M, Libralato G, Leone M, Galdiero E
* Metabolomic and oxidative effects of quantum dots-indolicidin on three generations of Daphnia magna (91 views)
Aquat Toxicol (ISSN: 0166-445xlinking), 2018 May; 198: 158-164.
Impact Factor: 0
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Oliveri V, Zimbone S, Giuffrida ML, Bellia F, Tomasello MF, Vecchio G
* Porphyrin Cyclodextrin Conjugates Modulate Amyloid Beta Peptide Aggregation and Cytotoxicity (361 views)
Chemistry (ISSN: 0947-6539, 1521-3765, 1521-3765electronic), 2018; 24(24): 6349-6353.
Impact Factor: 5.476
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Grasso GI, Bellia F, Arena G, Satriano C, Vecchio G, Rizzarelli E
* Multitarget trehalose-carnosine conjugates inhibit Aβ aggregation, tune copper(II) activity and decrease acrolein toxicity (416 views)
Eur J Med Chem (ISSN: 0223-5234, 1768-3254, 0223-5234linking), 2017 Jul 28; 135: 447-457.
Impact Factor: 4.816
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Sciacca MFM, Romanucci V, Zarrelli A, Monaco I, Lolicato F, Spinella N, Galati C, Grasso G, D'Urso L, Romeo M, Diomede L, Salmona M, Bongiorno C, Di Fabio G, La Rosa C, Milardi D
* Inhibition of Abeta Amyloid Growth and Toxicity by Silybins: The Crucial Role of Stereochemistry (401 views) (PDF 194 views)
Acs Chem Neurosci (ISSN: 1948-7193, 1948-7193electronic), 2017 Jun 09; N/D: N/D-N/D.
Impact Factor: 4.211
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Grasso G, Santoro AM, Lanza V, Sbardella D, Tundo GR, Ciaccio C, Marini S, Coletta M, Milardi D
* The double faced role of copper in Ab homeostasis: A survey on the interrelationship between metal dyshomeostasis, UPS functioning and autophagy in neurodegeneration (268 views)
Coordination Chemistry Reviews, 2017 Jun; N/D: 1-22.
Impact Factor: 13.324
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Florenzano F, Veronica C, Ciasca G, Ciotti MT, Pittaluga A, Olivero G, Feligioni M, Iannuzzi F, Latina V, Sciacca MFM, Sinopoli A, Milardi D, Pappalardo G, De Spirito M, Papi M, Atlante A, Bobba A, Borreca A, Calissano P, Amadoro G
* Extracellular truncated tau causes early presynaptic dysfunction associated with Alzheimer's disease and other tauopathies (262 views)
Oncotarget (ISSN: 1949-2553electronic, 1949-2553linking), 2017 Apr 22; N/D: N/D-N/D.
Impact Factor: 5.168
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Caraci F, Bruno V, Copani A, Matrisciano F, Nicoletti F, Battaglia G
* The impact of metabotropic glutamate receptors into active neurodegenerative processes: A "dark side" in the development of new symptomatic treatments for neurologic and psychiatric disorders (291 views)
Neuropharm (ISSN: 0028-3908, 1873-7064electronic, 0028-3908linking), 2017 Mar 15; 115: 180-192.
Impact Factor: 5.012
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Sandomenico A, Severino V, Apone F, De Lucia A, Caporale A, Doti N, Russo A, Russo R, Rega C, Del Giacco T, Falcigno L, Ruvo M, Chambery A
* Trifluoroacetylated tyrosine-rich D-tetrapeptides have potent antioxidant activity (401 views)
Peptides (ISSN: 0196-9781, 1873-5169electronic, 0196-9781linking), 2017 Mar; 89: 50-59.
Impact Factor: 2.851
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Oliveri V, Bellia F, Vecchio G
* Cyclodextrin Nanoparticles Bearing 8-Hydroxyquinoline Ligands as Multifunctional Biomaterials (737 views)
Chemistry (ISSN: 0947-6539, 1521-3765, 1521-3765electronic), 2017; 23(18): 4442-4449.
Impact Factor: 5.16
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D'Andrea LD, Rosa LD, Vigliotti C, Cataldi M
* VEGF mimic peptides: Potential applications in central nervous system therapeutics (624 views)
New Horizons Transl Med (ISSN: 2307-5023), 2017; 3(5): 233-251.
Impact Factor: 0
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Oliveri V, Bellia F, Grasso GI, Pietropaolo A, Vecchio G
* Trehalose-8-hydroxyquinoline conjugates as antioxidant modulators of Aβ aggregation (942 views)
Rsc Adv (ISSN: 2046-2069), 2016; 6(53): 47229-47236.
Impact Factor: 3.108
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Oliveri V, Bellia F, Vecchio G
* Cyclodextrin 3-functionalized with 8-hydroxyquinoline as an antioxidant inhibitor of metal-induced amyloid aggregation (426 views)
Chempluschem (ISSN: 2192-6506), 2015; 80(4): 762-770.
Impact Factor: 2.836
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Oliveri V, Grasso GI, Bellia F, Attanasio F, Viale M, Vecchio G
* Soluble sugar-based quinoline derivatives as new antioxidant modulators of metal-induced amyloid aggregation (681 views)
Inorg Chem (ISSN: 0020-1669, 1520-510x, 0020-1669linking), 2015; 54(6): 2591-2602.
Impact Factor: 4.82
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Bellia F, Rizzarelli E, Vecchio G
* The chemistry of carnosine derivatives (343 views)
Food And Nutritional Components In Focus (ISSN: 2045-1695), 2015; 2015-January(8): 61-83.
Impact Factor: 0
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Oliveri V, Bellia F, Pietropaolo A, Vecchio G
* Unusual Cyclodextrin Derivatives as a New Avenue to Modulate Self- and Metal-Induced Aβ Aggregation (515 views)
Chemistry (ISSN: 0947-6539, 1521-3765, 1521-3765electronic), 2015; 21(40): 14047-14059.
Impact Factor: 5.771
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Oliveri V, Attanasio F, Puglisi A, Spencer J, Sgarlata C, Vecchio G
* Multifunctional 8-hydroxyquinoline-appended cyclodextrins as new inhibitors of metal-induced protein aggregation (619 views)
Chemistry (ISSN: 0947-6539, 1521-3765, 1521-3765electronic), 2014 Jul 14; 20(29): 8954-8964.
Impact Factor: 5.731
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Salvatore E, Tedeschi E, Mollica C, Vicidomini C, Varrone A, Coda ARD, Brunetti A, Salvatore M, De Michele G, Filla A, Pappata S
* Supratentorial and infratentorial damage in spinocerebellar ataxia 2: a diffusion-weighted MRI study (376 views)
Mov Disord (ISSN: 0885-3185, 1531-8257, 0885-3185linking), 2014 May; 29(6): 780-786.
Impact Factor: 5.68
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Bellia F, Vecchio G, Rizzarelli E
* Carnosinases, Their Substrates And Diseases (659 views)
Molecules (ISSN: 1420-3049, 1420-3049electronic, 1420-3049linking), 2014 Feb 21; 19(2): 2299-2329.
Impact Factor: 2.416
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Grasso GI, Arena G, Bellia F, Rizzarelli E, Vecchio G
* Copper(II)-chelating homocarnosine glycoconjugate as a new multifunctional compound (530 views)
J Chem Res (ISSN: 0162-0134, 1873-3344, 0162-0134print), 2014 Feb; 131: 56-63.
Impact Factor: 3.444
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Dathan NA, Alterio V, Troiano E, Vullo D, Ludwig M, De Simone G, Supuran CT, Monti SM
* Biochemical Characterization Of The Chloroplastic β-Carbonic Anhydrase From Flaveria Bidentis (l. ) "kuntze" (449 views)
J Enzym Inhib Med Ch (ISSN: 1475-6366, 1475-6374electronic, 1475-6366linking), 2014; 29(4): 500-504.
Impact Factor: 2.332
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Russo GL, Russo M, Spagnuolo C, Tedesco I, Bilotto S, Iannitti R, Palumbo R
* Quercetin: a pleiotropic kinase inhibitor against cancer (450 views)
Cancer Treat Res (ISSN: 0927-3042), 2014; 159: 185-205.
Impact Factor: 9.284
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Bellia F, Oliveri V, Rizzarelli E, Vecchio G
* New derivative of carnosine for nanoparticle assemblies (457 views)
Eur J Med Chem (ISSN: 1768-3254, 0223-5234, 1768-3254electronic), 2013 Dec; 70: 225-232.
Impact Factor: 3.432
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Tedesco I, Russo M, Bilotto S, Spagnuolo C, Scognamiglio A, Palumbo R, Nappo A, Iacomino G, Moio L, Russo GL
* Dealcoholated red wine induces autophagic and apoptotic cell death in an osteosarcoma cell line (493 views)
Food Chem Toxicol (ISSN: 0278-6915), 2013; 60: 377-384.
Impact Factor: 2.61
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Caraci F, Battaglia G, Sortino MA, Spampinato S, Molinaro G, Copani A, Nicoletti F, Bruno V
* Metabotropic glutamate receptors in neurodegeneration/neuroprotection: Still a hot topic? (626 views)
Neurochem Int (ISSN: 0197-0186), 2012 Sep; 61(4): 559-565.
Impact Factor: 2.659
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Bellia F, Vecchio G, Rizzarelli E
* Carnosine derivatives: new multifunctional drug-like molecules (549 views)
Amino Acids (ISSN: 1438-2199, 0939-4451, 1438-2199electronic), 2012 Jul; 43(1): 153-163.
Impact Factor: 3.914
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Calabrese V, Cornelius C, Dinkova-Kostova AT, Iavicoli I, Di Paola R, Koverech A, Cuzzocrea S, Rizzarelli E, Calabrese EJ
* Cellular stress responses, hormetic phytochemicals and vitagenes in aging and longevity (3468 views)
Bba-Gen Subjects (ISSN: 0006-3002, 0925-4439, 1570-9639), 2012 May; 1822(5): 753-783.
Impact Factor: 3.733
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De Rosa V, Erkekoǧlu P, Forestier A, Favier A, Hincal F, Diamond AM, Douki T, Rachidi W
* Low doses of selenium specifically stimulate the repair of oxidative DNA damage in LNCaP prostate cancer cells (490 views)
Free Radic Res Free Radical Research (ISSN: 1071-5762), 2012; 46(2): 105-115.
Impact Factor: 3.279
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Arena G, Fattorusso R, Grasso G, Grasso GI, Isernia C, Malgieri G, Milardi D, Rizzarelli E
* Zinc(II) complexes of ubiquitin: speciation, affinity and binding features (559 views)
Chemistry (ISSN: 1521-3765, 0947-6539, 1521-3765electronic), 2011 Oct 4; 17(41): 11596-11603.
Impact Factor: 5.925
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Bellia F, Vecchio G, Cuzzocrea S, Calabrese V, Rizzarelli E
* Neuroprotective features of carnosine in oxidative driven diseases (424 views)
Molecular Aspects Of Medicine (ISSN: 1872-9452, 0098-2997), 2011 Sep; 32(4-6): 258-266.
Impact Factor: 9.97
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Lanza V, Bellia F, D'Agata R, Grasso G, Rizzarelli E, Vecchio G
* New glycoside derivatives of carnosine and analogs resistant to carnosinase hydrolysis: synthesis and characterization of their copper(II) complexes (402 views)
J Chem Res (ISSN: 1873-3344, 0162-0134, 0162-0134print), 2011 Feb; 105(2): 181-188.
Impact Factor: 3.354
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Limauro D, D'Ambrosio K, Langella E, De Simone G, Galdi I, Pedone C, Pedone E, Bartolucci S
* Exploring the catalytic mechanism of the first dimeric Bcp: Functional, structural and docking analyses of Bcp4 from Sulfolobus solfataricus (373 views)
Biochimie (ISSN: 1638-6183, 0300-9084, 1638-6183electronic), 2010 Oct; 92(10): 1435-1444.
Impact Factor: 3.787
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Erkekoǧlu P, Rachidi W, De Rosa V, Giray B, Favier A, Hincal F
* Protective effect of selenium supplementation on the genotoxicity of di(2-ethylhexyl)phthalate and mono(2-ethylhexyl)phthalate treatment in LNCaP cells (509 views)
Free Radic Biol Med (ISSN: 0891-5849, 0891-5849linking, 1873-4596electronic), 2010 Aug 15; 49(4): 559-566.
Impact Factor: 5.707
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Pedone E, Limauro D, Bartolucci S
* Erratum: The machinery for oxidative protein folding in thermophiles (Antioxidants and Redox Signaling (2008) 10 (157-169)) (363 views)
Antioxid Redox Signal (ISSN: 1523-0864, 1557-7716, 1523-0864linking), 2010; 12(1): 171-179.
Impact Factor: 8.209
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Bellia F, Calabrese V, Guarino F, Cavallaro M, Cornelius C, De Pinto V, Rizzarelli E
* Carnosinase levels in aging brain: redox state induction and cellular stress response (415 views)
Antioxid Redox Signal (ISSN: 1557-7716, 1523-0864, 1523-0864linking), 2009 Nov; 11(11): 2759-2775.
Impact Factor: 7.581
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Calabrese V, Cornelius C, Rizzarelli E, Owen JB, Dinkova-Kostova AT, Butterfield DA
* Nitric oxide in cell survival: a janus molecule (835 views)
Antioxid Redox Signal (ISSN: 1557-7716, 1523-0864, 1523-0864linking), 2009 Nov; 11(11): 2717-2739.
Impact Factor: 7.581
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La Mendola D, Pietropaolo A, Pappalardo G, Zannoni C, Rizzarelli E
* Prion Proteins Leading to Neurodegeneration (vol 5, pg 579, 2008) (233 views)
Current Alzheimer Research (ISSN: 1567-2050), 2009 Jun; 6(3): N/D-N/D.
Impact Factor: 4.971
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Calabrese V, Cornelius C, Mancuso C, Barone E, Calafato S, Bates T, Rizzarelli E, Kostova AT
* Vitagenes, dietary antioxidants and neuroprotection in neurodegenerative diseases (1116 views)
Frontiers In Bioscience (ISSN: 1093-4715, 1093-9946), 2009 Jan 1; 14: 376-397.
Impact Factor: 3.736
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Calabrese V, Cornelius C, Mancuso C, Pennisi G, Calafato S, Bellia F, Bates TE, Giuffrida Stella AM, Schapira T, Dinkova Kostova AT, Rizzarelli E
* Cellular stress response: a novel target for chemoprevention and nutritional neuroprotection in aging, neurodegenerative disorders and longevity (1171 views)
Neurochemical Research (ISSN: 1573-6903, 0364-3190), 2008 Dec; 33(12): 2444-2471.
Impact Factor: 2.26
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La Mendola D, Pietropaolo A, Pappalardo G, Zannoni C, Rizzarelli E
* Prion proteins leading to neurodegeneration (420 views)
Current Alzheimer Research (ISSN: 1567-2050), 2008 Dec; 5(6): 579-590.
Impact Factor: 4.132
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Caraci F, Busceti C, Biagioni F, Aronica E, Mastroiacovo F, Cappuccio I, Battaglia G, Bruno V, Caricasole A, Copani A, Nicoletti
* The Wnt antagonist, Dickkopf-1, as a target for the treatment of neurodegenerative disorders (384 views)
Neurochemical Research (ISSN: 0364-3190, 1573-6903), 2008 Dec; 33(12): 2401-2406.
Impact Factor: 2.26
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Esposito L, Seydel A, Aiello R, Sorrentino G, Cendron L, Zanotti G, Zagari
* The crystal structure of the superoxide dismutase from Helicobacter pylori reveals a structured C-terminal extension (380 views)
Bba-Gen Subjects (ISSN: 1570-9639, 0006-3002, 0925-4439), 2008 Nov; 1784(11): 1601-1606.
Impact Factor: 2.233
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Gustavsson T, Banyasz A, Sarkar N, Markovitsi D, Improta R
* Statin: New life for an old drug (365 views)
Pharmacol Res Academic Press, 2008 Jun 23; 350(1-3): 1-2.
Impact Factor: 3.976
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Limauro D, Pedone E, Galdi I, Bartolucci S
* Peroxiredoxins as cellular guardians in Sulfolobus solfataricus - characterization of Bcp1, Bcp3 and Bcp4 (366 views)
Febs Journal (ISSN: 1742-464x), 2008 May; 275(9): 2067-2077.
Impact Factor: 3.139
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Bellia F, Amorini AM, La Mendola D, Vecchio G, Tavazzi B, Giardina B, Di Pietro V, Lazzarino G, Rizzarelli E
* New glycosidic derivatives of histidine-containing dipeptides with antioxidant properties and resistant to carnosinase activity (444 views)
Eur J Med Chem (ISSN: 0223-5234, 1768-3254, 1768-3254electronic), 2008 Feb; 43(2): 373-380.
Impact Factor: 2.882
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Copani A, Guccione S, Giurato L, Caraci F, Calafiore M, Sortino MA
* The cell cycle molecules behind neurodegeneration in Alzheimer's disease: Perspectives for drug development (452 views)
Curr Med Chem (ISSN: 0929-8673, 1875-533x, 1875-533xelectronic), 2008; 15(24): 2420-2432.
Impact Factor: 4.823
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Calabrese V, Mancuso C, Calvani M, Rizzarelli E, Butterfield DA, Stella AM
* Nitric oxide in the central nervous system: neuroprotection versus neurotoxicity (720 views)
Nature Reviews Neuroscience (ISSN: 1471-0048), 2007 Oct; 8(10): 766-775.
Impact Factor: 24.52
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Amorini AM, Bellia F, Di Pietro V, Giardina B, La Mendola D, Lazzarino G, Sortino S, Tavazzi B, Rizzarelli E, Vecchio G
* Synthesis And Antioxidant Activity Of New Homocarnosine Beta-Cyclodextrin Conjugates (370 views)
Eur J Med Chem (ISSN: 0223-5234, 1768-3254, 1768-3254electronic), 2007 Jul; 42(7): 910-920.
Impact Factor: 2.301
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Bellia F, La Mendola D, Maccarrone G, Mineo P, Vitalini D, Scamporrino E, Sortino S, Vecchio G, Rizzarelli E
* Copper(II) Complexes With Beta-Cyclodextrin-Homocarnosine Conjugates And Their Antioxidant Activity (254 views)
Inorg Chim Acta (ISSN: 0020-1693), 2007 Feb 15; 360(3): 945-954.
Impact Factor: 1.713
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Calabrese V, Colombrita C, Guagliano E, Sapienza M, Ravagna A, Cardile V, Scapagnini G, Santoro AM, Mangiameli A, Butterfield DA, Giuffrida Stella AM, Rizzarelli E
* Protective effect of carnosine during nitrosative stress in astroglial cell cultures (379 views)
Neurochemical Research (ISSN: 0364-3190, 1573-6903), 2005 Jun; 30(6-7): 797-807.
Impact Factor: 2.187
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Tedesco I, Nappo A, Petitto F, Iacomino G, Nazzaro F, Palumbo R, Russo Gian L
* Antioxidant and cytotoxic properties of lyophilized beer extracts on HL-60 cell line (638 views)
Nutr Cancer (ISSN: 0163-5581), 2005; 52(1): 74-83.
Impact Factor: 2.426
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Russo M, Tedesco I, Iacomino G, Palumbo R, Galano G, Russo GL
* Dietary phytochemicals in chemoprevention of cancer (348 views)
Curr Med Chem (ISSN: 1568-0134), 2005; 5(1): 61-72.
Impact Factor: 3.715
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Caridi A, Cufari A, Lovino R, Palumbo R, Tedesco I
* Influence of Yeast on Polyphenol Composition of Wine (243 views)
Food Technol Biotechnol (ISSN: 1330-9862), 2004 Jan; 42(1): 37-40.
Impact Factor: 0.475
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Russo M, Palumbo R, Mupo A, Tosto M, Iacomino G, Scognamiglio A, Tedesco I, Galano G, Russo GL
* Flavonoid quercetin sensitizes a CD95-resistant cell line to apoptosis by activating protein kinase Cα (436 views)
Oncogene (ISSN: 0950-9232, 1476-5594), 2003; 22(21): 3330-3342.
Impact Factor: 6.495
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Bonomo RP, Bruno V, Conte E, De Guidi G, La Mendola D, Maccarrone G, Nicoletti F, Rizzarelli E, Sortino S, Vecchio G
* Potentiometric, spectroscopic and antioxidant activity studies of SOD mimics containing carnosine (385 views)
Dalton T (ISSN: 1477-9226, 1477-9234, 1477-9234electronic), 2003; (23): 4406-4415.
Impact Factor: 2.908
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Borrelli RC, Fogliano V, Monti SM, Ames JM
* Characterization of melanoidins from a glucose-glycine model system (243 views)
Eur Food Res Technol (ISSN: 1438-2377), 2002 Sep; 215(3): 210-215.
Impact Factor: 1.021
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La Mendola D, Sortino S, Rizzarelli E, Vecchiog
* Synthesis Of New Carnosine Derivatives Of R-Cyclodextrin And Their Hydroxyl Radical Scavanger Ability (320 views)
Helvetica Chimica Acta, 2002; 85: 1633-1643.
Impact Factor: 1.394
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Tedesco I, Russo GL, Nazzaro F, Russo M, Palumbo R
* Antioxidant effect of red wine anthocyanins in normal and catalase-inactive human erythrocytes (869 views)
J Nutr Biochem (ISSN: 0955-2863), 2001 Sep; 12(9): 505-511.
Impact Factor: 1.039
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Monti SM, Ritieni A, Sacchi R, Skog K, Borgen E, Fogliano V
* Characterization of phenolic compounds in virgin olive oil and their effect on the formation of carcinogenic/mutagenic heterocyclic amines in a model system (612 views)
J Agric Food Chem (ISSN: 0021-8561), 2001 Sep; 49(8): 3969-3975.
Impact Factor: 1.576
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Tedesco I, Russo M, Russo P, Iacomino G, Russo GL, Carraturo A, Faruolo C, Moio L, Palumbo R
Antioxidant effect of red wine polyphenols on red blood cells (549 views)
J Nutr Biochem (ISSN: 0955-2863), 2000 Feb; 11(2): 114-119.
Impact Factor: 1.083
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Monti SM, Borrelli RC, Ritieni A, Fogliano V
A comparison of color formation and Maillard reaction products of a lactose-lysine and lactose-N(α)-acetyllysine model system (469 views)
J Agric Food Chem (ISSN: 0021-8561), 2000; 48(4): 1041-1046.
Impact Factor: 1.56
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Fogliano V, Ritieni A, Monti SM, Gallo M, Della Medaglia D, Ambrosino ML, Sacchi R
Antioxidant activity of virgin olive oil phenolic compounds in a micellar system (301 views)
Journal Of The Science Of Food And Agriculture (ISSN: 0022-5142), 1999 Oct; 79(13): 1803-1808.
Impact Factor: 1.097
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Wink DA, Vodovotz Y, Grisham MB, DeGraff W, Cook JC, Pacelli R, Krishna M, Mitchell JB
Antioxidant effects of nitric oxide (351 views)
Method Enzymol (ISSN: 0076-6879, 1557-7988electronic), 1998; 301: 413-424.
Impact Factor: 2.823
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Wink DA, Cook JA, Pacelli R, DeGraff W, Gamson J, Liebmann J, Krishna MC, Mitchell JB
The effect of various nitric oxide-donor agents on hydrogen peroxide-mediated toxicity: A direct correlation between nitric oxide formation and protection (685 views)
Arch Bioch Bioph (ISSN: 0003-9861, 0003-9861linking), 1996 Jul 15; 331(2): 241-248.
Impact Factor: 2.649
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Wink DA, Grisham MB, Miles AM, Nims RW, Krishna MC, Pacelli R, Teague D, Poore CM, Cook JA, Ford PC
Determination of selectivity of reactive nitrogen oxide species for various substrates (366 views)
Method Enzymol (ISSN: 0076-6879, 1557-7988electronic, 0076-6879linking), 1996; 268: 120-130.
Impact Factor: 2.435
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Bonomo RP, De Flora A, Rizzarelli E, Santoro AM, Tabbì G, Tonetti M
Copper(II) complexes encapsulated in human red blood cells (587 views)
J Chem Res (ISSN: 0162-0134, 1873-3344, 0162-0134print), 1995 Sep; 59(4): 773-784.
Impact Factor: 1.342
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Costanzo LL, De Guidi G, Giuffrida S, Sortino S, Condorelli G, Pappalardo G
Antioxidant effect of copper(II) on photosensitized lipid peroxidation (609 views)
J Chem Res (ISSN: 0162-0134print, 0162-0134linking, 1873-3344), 1995 Feb; 57(2): 115-125.
Impact Factor: 1.342
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* Validation of FDG-PET datasets of normal controls for the extraction of SPM-based brain metabolism maps (6 views)
Eur J Nucl Med Mol Imaging (ISSN: 1619-7070linking), 2021 Jul; 48(8): 2486-2499.
Impact Factor: 9.236
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Pedone E, Fiorentino G, Bartolucci S, Limauro D
* Enzymatic Antioxidant Signatures in Hyperthermophilic Archaea (57 views)
Antioxidants (ISSN: 2076-3921linking), 2020 Aug 3; 9(8): N/D-N/D.
Impact Factor: 4.52
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Rendina A, Drongitis D, Donizetti A, Fucci L, Milan G, Tripodi F, Giustezza F, Postiglione A, Pappata S, Ferrari R, Bossù P, Angiolillo A, Di Costanzo A, Caiazzo M, Vitale E
* CD33 and SIGLECL1 Immunoglobulin Superfamily Involved in Dementia (94 views)
J Neuropathol Exp Neurol (ISSN: 0022-3069linking), 2020 Jul 10; 79(8): 891-901.
Impact Factor: 3.51
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Dubbioso R, Ruggiero L, Esposito M, Tarantino P, De Angelis M, Aruta F, Pappata S, Ugga L, Piperno A, Iorio R, Santoro L, Iodice R, Manganelli F
* Different cortical excitability profiles in hereditary brain iron and copper accumulation (131 views)
Neurol Sci (ISSN: 1590-1874linking, 1590-3478), 2020 Mar; 41(3): 679-685.
Impact Factor: 1.315
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Spampinato SF, Copani A, Nicoletti F, Sortino MA, Caraci F
* Metabotropic Glutamate Receptors in Glial Cells: A New Potential Target for Neuroprotection? (231 views)
Front Mol Neurosci (ISSN: 1662-5099, 1662-5099linking, 1662-5099electronic), 2018 Nov 13; 11: 414-414.
Impact Factor: 3.902
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Falanga A, Mercurio FA, Siciliano A, Lombardi L, Galdiero S, Guida M, Libralato G, Leone M, Galdiero E
* Metabolomic and oxidative effects of quantum dots-indolicidin on three generations of Daphnia magna (91 views)
Aquat Toxicol (ISSN: 0166-445xlinking), 2018 May; 198: 158-164.
Impact Factor: 0
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Oliveri V, Zimbone S, Giuffrida ML, Bellia F, Tomasello MF, Vecchio G
* Porphyrin Cyclodextrin Conjugates Modulate Amyloid Beta Peptide Aggregation and Cytotoxicity (361 views)
Chemistry (ISSN: 0947-6539, 1521-3765, 1521-3765electronic), 2018; 24(24): 6349-6353.
Impact Factor: 5.476
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Grasso GI, Bellia F, Arena G, Satriano C, Vecchio G, Rizzarelli E
* Multitarget trehalose-carnosine conjugates inhibit Aβ aggregation, tune copper(II) activity and decrease acrolein toxicity (416 views)
Eur J Med Chem (ISSN: 0223-5234, 1768-3254, 0223-5234linking), 2017 Jul 28; 135: 447-457.
Impact Factor: 4.816
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Sciacca MFM, Romanucci V, Zarrelli A, Monaco I, Lolicato F, Spinella N, Galati C, Grasso G, D'Urso L, Romeo M, Diomede L, Salmona M, Bongiorno C, Di Fabio G, La Rosa C, Milardi D
* Inhibition of Abeta Amyloid Growth and Toxicity by Silybins: The Crucial Role of Stereochemistry (401 views) (PDF 194 views)
Acs Chem Neurosci (ISSN: 1948-7193, 1948-7193electronic), 2017 Jun 09; N/D: N/D-N/D.
Impact Factor: 4.211
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Grasso G, Santoro AM, Lanza V, Sbardella D, Tundo GR, Ciaccio C, Marini S, Coletta M, Milardi D
* The double faced role of copper in Ab homeostasis: A survey on the interrelationship between metal dyshomeostasis, UPS functioning and autophagy in neurodegeneration (268 views)
Coordination Chemistry Reviews, 2017 Jun; N/D: 1-22.
Impact Factor: 13.324
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Florenzano F, Veronica C, Ciasca G, Ciotti MT, Pittaluga A, Olivero G, Feligioni M, Iannuzzi F, Latina V, Sciacca MFM, Sinopoli A, Milardi D, Pappalardo G, De Spirito M, Papi M, Atlante A, Bobba A, Borreca A, Calissano P, Amadoro G
* Extracellular truncated tau causes early presynaptic dysfunction associated with Alzheimer's disease and other tauopathies (262 views)
Oncotarget (ISSN: 1949-2553electronic, 1949-2553linking), 2017 Apr 22; N/D: N/D-N/D.
Impact Factor: 5.168
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Caraci F, Bruno V, Copani A, Matrisciano F, Nicoletti F, Battaglia G
* The impact of metabotropic glutamate receptors into active neurodegenerative processes: A "dark side" in the development of new symptomatic treatments for neurologic and psychiatric disorders (291 views)
Neuropharm (ISSN: 0028-3908, 1873-7064electronic, 0028-3908linking), 2017 Mar 15; 115: 180-192.
Impact Factor: 5.012
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Sandomenico A, Severino V, Apone F, De Lucia A, Caporale A, Doti N, Russo A, Russo R, Rega C, Del Giacco T, Falcigno L, Ruvo M, Chambery A
* Trifluoroacetylated tyrosine-rich D-tetrapeptides have potent antioxidant activity (401 views)
Peptides (ISSN: 0196-9781, 1873-5169electronic, 0196-9781linking), 2017 Mar; 89: 50-59.
Impact Factor: 2.851
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Oliveri V, Bellia F, Vecchio G
* Cyclodextrin Nanoparticles Bearing 8-Hydroxyquinoline Ligands as Multifunctional Biomaterials (737 views)
Chemistry (ISSN: 0947-6539, 1521-3765, 1521-3765electronic), 2017; 23(18): 4442-4449.
Impact Factor: 5.16
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D'Andrea LD, Rosa LD, Vigliotti C, Cataldi M
* VEGF mimic peptides: Potential applications in central nervous system therapeutics (624 views)
New Horizons Transl Med (ISSN: 2307-5023), 2017; 3(5): 233-251.
Impact Factor: 0
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Oliveri V, Bellia F, Grasso GI, Pietropaolo A, Vecchio G
* Trehalose-8-hydroxyquinoline conjugates as antioxidant modulators of Aβ aggregation (942 views)
Rsc Adv (ISSN: 2046-2069), 2016; 6(53): 47229-47236.
Impact Factor: 3.108
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Oliveri V, Bellia F, Vecchio G
* Cyclodextrin 3-functionalized with 8-hydroxyquinoline as an antioxidant inhibitor of metal-induced amyloid aggregation (426 views)
Chempluschem (ISSN: 2192-6506), 2015; 80(4): 762-770.
Impact Factor: 2.836
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Oliveri V, Grasso GI, Bellia F, Attanasio F, Viale M, Vecchio G
* Soluble sugar-based quinoline derivatives as new antioxidant modulators of metal-induced amyloid aggregation (681 views)
Inorg Chem (ISSN: 0020-1669, 1520-510x, 0020-1669linking), 2015; 54(6): 2591-2602.
Impact Factor: 4.82
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Bellia F, Rizzarelli E, Vecchio G
* The chemistry of carnosine derivatives (343 views)
Food And Nutritional Components In Focus (ISSN: 2045-1695), 2015; 2015-January(8): 61-83.
Impact Factor: 0
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Oliveri V, Bellia F, Pietropaolo A, Vecchio G
* Unusual Cyclodextrin Derivatives as a New Avenue to Modulate Self- and Metal-Induced Aβ Aggregation (515 views)
Chemistry (ISSN: 0947-6539, 1521-3765, 1521-3765electronic), 2015; 21(40): 14047-14059.
Impact Factor: 5.771
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Oliveri V, Attanasio F, Puglisi A, Spencer J, Sgarlata C, Vecchio G
* Multifunctional 8-hydroxyquinoline-appended cyclodextrins as new inhibitors of metal-induced protein aggregation (619 views)
Chemistry (ISSN: 0947-6539, 1521-3765, 1521-3765electronic), 2014 Jul 14; 20(29): 8954-8964.
Impact Factor: 5.731
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Salvatore E, Tedeschi E, Mollica C, Vicidomini C, Varrone A, Coda ARD, Brunetti A, Salvatore M, De Michele G, Filla A, Pappata S
* Supratentorial and infratentorial damage in spinocerebellar ataxia 2: a diffusion-weighted MRI study (376 views)
Mov Disord (ISSN: 0885-3185, 1531-8257, 0885-3185linking), 2014 May; 29(6): 780-786.
Impact Factor: 5.68
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Bellia F, Vecchio G, Rizzarelli E
* Carnosinases, Their Substrates And Diseases (659 views)
Molecules (ISSN: 1420-3049, 1420-3049electronic, 1420-3049linking), 2014 Feb 21; 19(2): 2299-2329.
Impact Factor: 2.416
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Grasso GI, Arena G, Bellia F, Rizzarelli E, Vecchio G
* Copper(II)-chelating homocarnosine glycoconjugate as a new multifunctional compound (530 views)
J Chem Res (ISSN: 0162-0134, 1873-3344, 0162-0134print), 2014 Feb; 131: 56-63.
Impact Factor: 3.444
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Dathan NA, Alterio V, Troiano E, Vullo D, Ludwig M, De Simone G, Supuran CT, Monti SM
* Biochemical Characterization Of The Chloroplastic β-Carbonic Anhydrase From Flaveria Bidentis (l. ) "kuntze" (449 views)
J Enzym Inhib Med Ch (ISSN: 1475-6366, 1475-6374electronic, 1475-6366linking), 2014; 29(4): 500-504.
Impact Factor: 2.332
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Russo GL, Russo M, Spagnuolo C, Tedesco I, Bilotto S, Iannitti R, Palumbo R
* Quercetin: a pleiotropic kinase inhibitor against cancer (450 views)
Cancer Treat Res (ISSN: 0927-3042), 2014; 159: 185-205.
Impact Factor: 9.284
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Bellia F, Oliveri V, Rizzarelli E, Vecchio G
* New derivative of carnosine for nanoparticle assemblies (457 views)
Eur J Med Chem (ISSN: 1768-3254, 0223-5234, 1768-3254electronic), 2013 Dec; 70: 225-232.
Impact Factor: 3.432
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Tedesco I, Russo M, Bilotto S, Spagnuolo C, Scognamiglio A, Palumbo R, Nappo A, Iacomino G, Moio L, Russo GL
* Dealcoholated red wine induces autophagic and apoptotic cell death in an osteosarcoma cell line (493 views)
Food Chem Toxicol (ISSN: 0278-6915), 2013; 60: 377-384.
Impact Factor: 2.61
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Caraci F, Battaglia G, Sortino MA, Spampinato S, Molinaro G, Copani A, Nicoletti F, Bruno V
* Metabotropic glutamate receptors in neurodegeneration/neuroprotection: Still a hot topic? (626 views)
Neurochem Int (ISSN: 0197-0186), 2012 Sep; 61(4): 559-565.
Impact Factor: 2.659
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Bellia F, Vecchio G, Rizzarelli E
* Carnosine derivatives: new multifunctional drug-like molecules (549 views)
Amino Acids (ISSN: 1438-2199, 0939-4451, 1438-2199electronic), 2012 Jul; 43(1): 153-163.
Impact Factor: 3.914
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Calabrese V, Cornelius C, Dinkova-Kostova AT, Iavicoli I, Di Paola R, Koverech A, Cuzzocrea S, Rizzarelli E, Calabrese EJ
* Cellular stress responses, hormetic phytochemicals and vitagenes in aging and longevity (3468 views)
Bba-Gen Subjects (ISSN: 0006-3002, 0925-4439, 1570-9639), 2012 May; 1822(5): 753-783.
Impact Factor: 3.733
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De Rosa V, Erkekoǧlu P, Forestier A, Favier A, Hincal F, Diamond AM, Douki T, Rachidi W
* Low doses of selenium specifically stimulate the repair of oxidative DNA damage in LNCaP prostate cancer cells (490 views)
Free Radic Res Free Radical Research (ISSN: 1071-5762), 2012; 46(2): 105-115.
Impact Factor: 3.279
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Arena G, Fattorusso R, Grasso G, Grasso GI, Isernia C, Malgieri G, Milardi D, Rizzarelli E
* Zinc(II) complexes of ubiquitin: speciation, affinity and binding features (559 views)
Chemistry (ISSN: 1521-3765, 0947-6539, 1521-3765electronic), 2011 Oct 4; 17(41): 11596-11603.
Impact Factor: 5.925
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Bellia F, Vecchio G, Cuzzocrea S, Calabrese V, Rizzarelli E
* Neuroprotective features of carnosine in oxidative driven diseases (424 views)
Molecular Aspects Of Medicine (ISSN: 1872-9452, 0098-2997), 2011 Sep; 32(4-6): 258-266.
Impact Factor: 9.97
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Lanza V, Bellia F, D'Agata R, Grasso G, Rizzarelli E, Vecchio G
* New glycoside derivatives of carnosine and analogs resistant to carnosinase hydrolysis: synthesis and characterization of their copper(II) complexes (402 views)
J Chem Res (ISSN: 1873-3344, 0162-0134, 0162-0134print), 2011 Feb; 105(2): 181-188.
Impact Factor: 3.354
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Limauro D, D'Ambrosio K, Langella E, De Simone G, Galdi I, Pedone C, Pedone E, Bartolucci S
* Exploring the catalytic mechanism of the first dimeric Bcp: Functional, structural and docking analyses of Bcp4 from Sulfolobus solfataricus (373 views)
Biochimie (ISSN: 1638-6183, 0300-9084, 1638-6183electronic), 2010 Oct; 92(10): 1435-1444.
Impact Factor: 3.787
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Erkekoǧlu P, Rachidi W, De Rosa V, Giray B, Favier A, Hincal F
* Protective effect of selenium supplementation on the genotoxicity of di(2-ethylhexyl)phthalate and mono(2-ethylhexyl)phthalate treatment in LNCaP cells (509 views)
Free Radic Biol Med (ISSN: 0891-5849, 0891-5849linking, 1873-4596electronic), 2010 Aug 15; 49(4): 559-566.
Impact Factor: 5.707
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Pedone E, Limauro D, Bartolucci S
* Erratum: The machinery for oxidative protein folding in thermophiles (Antioxidants and Redox Signaling (2008) 10 (157-169)) (363 views)
Antioxid Redox Signal (ISSN: 1523-0864, 1557-7716, 1523-0864linking), 2010; 12(1): 171-179.
Impact Factor: 8.209
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Bellia F, Calabrese V, Guarino F, Cavallaro M, Cornelius C, De Pinto V, Rizzarelli E
* Carnosinase levels in aging brain: redox state induction and cellular stress response (415 views)
Antioxid Redox Signal (ISSN: 1557-7716, 1523-0864, 1523-0864linking), 2009 Nov; 11(11): 2759-2775.
Impact Factor: 7.581
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Calabrese V, Cornelius C, Rizzarelli E, Owen JB, Dinkova-Kostova AT, Butterfield DA
* Nitric oxide in cell survival: a janus molecule (835 views)
Antioxid Redox Signal (ISSN: 1557-7716, 1523-0864, 1523-0864linking), 2009 Nov; 11(11): 2717-2739.
Impact Factor: 7.581
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La Mendola D, Pietropaolo A, Pappalardo G, Zannoni C, Rizzarelli E
* Prion Proteins Leading to Neurodegeneration (vol 5, pg 579, 2008) (233 views)
Current Alzheimer Research (ISSN: 1567-2050), 2009 Jun; 6(3): N/D-N/D.
Impact Factor: 4.971
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Calabrese V, Cornelius C, Mancuso C, Barone E, Calafato S, Bates T, Rizzarelli E, Kostova AT
* Vitagenes, dietary antioxidants and neuroprotection in neurodegenerative diseases (1116 views)
Frontiers In Bioscience (ISSN: 1093-4715, 1093-9946), 2009 Jan 1; 14: 376-397.
Impact Factor: 3.736
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Calabrese V, Cornelius C, Mancuso C, Pennisi G, Calafato S, Bellia F, Bates TE, Giuffrida Stella AM, Schapira T, Dinkova Kostova AT, Rizzarelli E
* Cellular stress response: a novel target for chemoprevention and nutritional neuroprotection in aging, neurodegenerative disorders and longevity (1171 views)
Neurochemical Research (ISSN: 1573-6903, 0364-3190), 2008 Dec; 33(12): 2444-2471.
Impact Factor: 2.26
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La Mendola D, Pietropaolo A, Pappalardo G, Zannoni C, Rizzarelli E
* Prion proteins leading to neurodegeneration (420 views)
Current Alzheimer Research (ISSN: 1567-2050), 2008 Dec; 5(6): 579-590.
Impact Factor: 4.132
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Caraci F, Busceti C, Biagioni F, Aronica E, Mastroiacovo F, Cappuccio I, Battaglia G, Bruno V, Caricasole A, Copani A, Nicoletti
* The Wnt antagonist, Dickkopf-1, as a target for the treatment of neurodegenerative disorders (384 views)
Neurochemical Research (ISSN: 0364-3190, 1573-6903), 2008 Dec; 33(12): 2401-2406.
Impact Factor: 2.26
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Esposito L, Seydel A, Aiello R, Sorrentino G, Cendron L, Zanotti G, Zagari
* The crystal structure of the superoxide dismutase from Helicobacter pylori reveals a structured C-terminal extension (380 views)
Bba-Gen Subjects (ISSN: 1570-9639, 0006-3002, 0925-4439), 2008 Nov; 1784(11): 1601-1606.
Impact Factor: 2.233
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Gustavsson T, Banyasz A, Sarkar N, Markovitsi D, Improta R
* Statin: New life for an old drug (365 views)
Pharmacol Res Academic Press, 2008 Jun 23; 350(1-3): 1-2.
Impact Factor: 3.976
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Limauro D, Pedone E, Galdi I, Bartolucci S
* Peroxiredoxins as cellular guardians in Sulfolobus solfataricus - characterization of Bcp1, Bcp3 and Bcp4 (366 views)
Febs Journal (ISSN: 1742-464x), 2008 May; 275(9): 2067-2077.
Impact Factor: 3.139
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Bellia F, Amorini AM, La Mendola D, Vecchio G, Tavazzi B, Giardina B, Di Pietro V, Lazzarino G, Rizzarelli E
* New glycosidic derivatives of histidine-containing dipeptides with antioxidant properties and resistant to carnosinase activity (444 views)
Eur J Med Chem (ISSN: 0223-5234, 1768-3254, 1768-3254electronic), 2008 Feb; 43(2): 373-380.
Impact Factor: 2.882
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Copani A, Guccione S, Giurato L, Caraci F, Calafiore M, Sortino MA
* The cell cycle molecules behind neurodegeneration in Alzheimer's disease: Perspectives for drug development (452 views)
Curr Med Chem (ISSN: 0929-8673, 1875-533x, 1875-533xelectronic), 2008; 15(24): 2420-2432.
Impact Factor: 4.823
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Calabrese V, Mancuso C, Calvani M, Rizzarelli E, Butterfield DA, Stella AM
* Nitric oxide in the central nervous system: neuroprotection versus neurotoxicity (720 views)
Nature Reviews Neuroscience (ISSN: 1471-0048), 2007 Oct; 8(10): 766-775.
Impact Factor: 24.52
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Amorini AM, Bellia F, Di Pietro V, Giardina B, La Mendola D, Lazzarino G, Sortino S, Tavazzi B, Rizzarelli E, Vecchio G
* Synthesis And Antioxidant Activity Of New Homocarnosine Beta-Cyclodextrin Conjugates (370 views)
Eur J Med Chem (ISSN: 0223-5234, 1768-3254, 1768-3254electronic), 2007 Jul; 42(7): 910-920.
Impact Factor: 2.301
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Bellia F, La Mendola D, Maccarrone G, Mineo P, Vitalini D, Scamporrino E, Sortino S, Vecchio G, Rizzarelli E
* Copper(II) Complexes With Beta-Cyclodextrin-Homocarnosine Conjugates And Their Antioxidant Activity (254 views)
Inorg Chim Acta (ISSN: 0020-1693), 2007 Feb 15; 360(3): 945-954.
Impact Factor: 1.713
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Calabrese V, Colombrita C, Guagliano E, Sapienza M, Ravagna A, Cardile V, Scapagnini G, Santoro AM, Mangiameli A, Butterfield DA, Giuffrida Stella AM, Rizzarelli E
* Protective effect of carnosine during nitrosative stress in astroglial cell cultures (379 views)
Neurochemical Research (ISSN: 0364-3190, 1573-6903), 2005 Jun; 30(6-7): 797-807.
Impact Factor: 2.187
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Tedesco I, Nappo A, Petitto F, Iacomino G, Nazzaro F, Palumbo R, Russo Gian L
* Antioxidant and cytotoxic properties of lyophilized beer extracts on HL-60 cell line (638 views)
Nutr Cancer (ISSN: 0163-5581), 2005; 52(1): 74-83.
Impact Factor: 2.426
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Russo M, Tedesco I, Iacomino G, Palumbo R, Galano G, Russo GL
* Dietary phytochemicals in chemoprevention of cancer (348 views)
Curr Med Chem (ISSN: 1568-0134), 2005; 5(1): 61-72.
Impact Factor: 3.715
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Caridi A, Cufari A, Lovino R, Palumbo R, Tedesco I
* Influence of Yeast on Polyphenol Composition of Wine (243 views)
Food Technol Biotechnol (ISSN: 1330-9862), 2004 Jan; 42(1): 37-40.
Impact Factor: 0.475
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Russo M, Palumbo R, Mupo A, Tosto M, Iacomino G, Scognamiglio A, Tedesco I, Galano G, Russo GL
* Flavonoid quercetin sensitizes a CD95-resistant cell line to apoptosis by activating protein kinase Cα (436 views)
Oncogene (ISSN: 0950-9232, 1476-5594), 2003; 22(21): 3330-3342.
Impact Factor: 6.495
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Bonomo RP, Bruno V, Conte E, De Guidi G, La Mendola D, Maccarrone G, Nicoletti F, Rizzarelli E, Sortino S, Vecchio G
* Potentiometric, spectroscopic and antioxidant activity studies of SOD mimics containing carnosine (385 views)
Dalton T (ISSN: 1477-9226, 1477-9234, 1477-9234electronic), 2003; (23): 4406-4415.
Impact Factor: 2.908
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Borrelli RC, Fogliano V, Monti SM, Ames JM
* Characterization of melanoidins from a glucose-glycine model system (243 views)
Eur Food Res Technol (ISSN: 1438-2377), 2002 Sep; 215(3): 210-215.
Impact Factor: 1.021
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La Mendola D, Sortino S, Rizzarelli E, Vecchiog
* Synthesis Of New Carnosine Derivatives Of R-Cyclodextrin And Their Hydroxyl Radical Scavanger Ability (320 views)
Helvetica Chimica Acta, 2002; 85: 1633-1643.
Impact Factor: 1.394
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Tedesco I, Russo GL, Nazzaro F, Russo M, Palumbo R
* Antioxidant effect of red wine anthocyanins in normal and catalase-inactive human erythrocytes (869 views)
J Nutr Biochem (ISSN: 0955-2863), 2001 Sep; 12(9): 505-511.
Impact Factor: 1.039
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Monti SM, Ritieni A, Sacchi R, Skog K, Borgen E, Fogliano V
* Characterization of phenolic compounds in virgin olive oil and their effect on the formation of carcinogenic/mutagenic heterocyclic amines in a model system (612 views)
J Agric Food Chem (ISSN: 0021-8561), 2001 Sep; 49(8): 3969-3975.
Impact Factor: 1.576
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Tedesco I, Russo M, Russo P, Iacomino G, Russo GL, Carraturo A, Faruolo C, Moio L, Palumbo R
Antioxidant effect of red wine polyphenols on red blood cells (549 views)
J Nutr Biochem (ISSN: 0955-2863), 2000 Feb; 11(2): 114-119.
Impact Factor: 1.083
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Monti SM, Borrelli RC, Ritieni A, Fogliano V
A comparison of color formation and Maillard reaction products of a lactose-lysine and lactose-N(α)-acetyllysine model system (469 views)
J Agric Food Chem (ISSN: 0021-8561), 2000; 48(4): 1041-1046.
Impact Factor: 1.56
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Fogliano V, Ritieni A, Monti SM, Gallo M, Della Medaglia D, Ambrosino ML, Sacchi R
Antioxidant activity of virgin olive oil phenolic compounds in a micellar system (301 views)
Journal Of The Science Of Food And Agriculture (ISSN: 0022-5142), 1999 Oct; 79(13): 1803-1808.
Impact Factor: 1.097
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Wink DA, Vodovotz Y, Grisham MB, DeGraff W, Cook JC, Pacelli R, Krishna M, Mitchell JB
Antioxidant effects of nitric oxide (351 views)
Method Enzymol (ISSN: 0076-6879, 1557-7988electronic), 1998; 301: 413-424.
Impact Factor: 2.823
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Wink DA, Cook JA, Pacelli R, DeGraff W, Gamson J, Liebmann J, Krishna MC, Mitchell JB
The effect of various nitric oxide-donor agents on hydrogen peroxide-mediated toxicity: A direct correlation between nitric oxide formation and protection (685 views)
Arch Bioch Bioph (ISSN: 0003-9861, 0003-9861linking), 1996 Jul 15; 331(2): 241-248.
Impact Factor: 2.649
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Wink DA, Grisham MB, Miles AM, Nims RW, Krishna MC, Pacelli R, Teague D, Poore CM, Cook JA, Ford PC
Determination of selectivity of reactive nitrogen oxide species for various substrates (366 views)
Method Enzymol (ISSN: 0076-6879, 1557-7988electronic, 0076-6879linking), 1996; 268: 120-130.
Impact Factor: 2.435
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Bonomo RP, De Flora A, Rizzarelli E, Santoro AM, Tabbì G, Tonetti M
Copper(II) complexes encapsulated in human red blood cells (587 views)
J Chem Res (ISSN: 0162-0134, 1873-3344, 0162-0134print), 1995 Sep; 59(4): 773-784.
Impact Factor: 1.342
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Costanzo LL, De Guidi G, Giuffrida S, Sortino S, Condorelli G, Pappalardo G
Antioxidant effect of copper(II) on photosensitized lipid peroxidation (609 views)
J Chem Res (ISSN: 0162-0134print, 0162-0134linking, 1873-3344), 1995 Feb; 57(2): 115-125.
Impact Factor: 1.342
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71 Records (69 excluding Abstracts).
Total impact factor: 286.177 (279.864 excluding Abstracts).
Total 5 year impact factor: 287.15 (279.77 excluding Abstracts).
Total impact factor: 286.177 (279.864 excluding Abstracts).
Total 5 year impact factor: 287.15 (279.77 excluding Abstracts).
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