Coronary vascular function in patients with resistant hypertension and normal myocardial perfusion: a propensity score analysis (267 views)
Eur Heart J-Card Img (ISSN: 2047-2404linking, 2047-2412electronic), 2019 Feb 14; N/D: N/D-N/D.
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Paper type: Journal Article,
Impact factor: 3.669, 5-year impact factor: 3.669
Url: Not available.
Keywords: Pet, Myocardial Blood Flow, Myocardial Perfusion Reserve, Resistant Hypertension, Pet Ct,
Affiliations:
*** IBB - CNR ***
Institute of Biostructure and Bioimaging, National Council of Research, Via De Amicis 95, Naples, Italy., Department of Advanced Biomedical Sciences, University Federico II, Via Pansini 5, Naples, Italy., Department of Translational Medical Sciences, University Federico II, Via Pansini 5, Naples, Italy., Department of Nuclear Medicine, Academic Medical Center University of Amsterdam, Meibergdreef 9, AZ, Amsterdam, The Netherlands., Department of Nuclear Medicine, Central Manchester Foundation Trust, Manchester, UK.,
References:
Not available.
Eur Heart J-Card Img (ISSN: 2047-2404linking, 2047-2412electronic), 2019 Feb 14; N/D: N/D-N/D.
Export to BibTeX Export to EndNote
Paper type: Journal Article,
Impact factor: 3.669, 5-year impact factor: 3.669
Url: Not available.
Keywords: Pet, Myocardial Blood Flow, Myocardial Perfusion Reserve, Resistant Hypertension, Pet Ct,
Affiliations:
*** IBB - CNR ***
Institute of Biostructure and Bioimaging, National Council of Research, Via De Amicis 95, Naples, Italy., Department of Advanced Biomedical Sciences, University Federico II, Via Pansini 5, Naples, Italy., Department of Translational Medical Sciences, University Federico II, Via Pansini 5, Naples, Italy., Department of Nuclear Medicine, Academic Medical Center University of Amsterdam, Meibergdreef 9, AZ, Amsterdam, The Netherlands., Department of Nuclear Medicine, Central Manchester Foundation Trust, Manchester, UK.,
References:
Not available.
Coronary vascular function in patients with resistant hypertension and normal myocardial perfusion: a propensity score analysis
AIMS: Impaired myocardial perfusion reserve (MPR) may occur earlier than coronary atherosclerosis and it may be an early manifestation of developing coronary artery disease (CAD) in patients with resistant hypertension (RH). We evaluated the relationship between RH and MPR in patients with systemic arterial hypertension after balancing for coronary risk factors. METHODS AND RESULTS: We studied 360 subjects without overt CAD and normal myocardial perfusion at stress-rest 82Rb positron emission tomography/computed tomography. To account for differences in baseline characteristics between patients with resistant and controlled hypertension, we created a propensity score-matched cohort considering clinical variables and coronary risk factors. Before matching, patients with RH were significantly older, had higher prevalence of male gender and hypercholesterolaemia, and showed significantly lower global hyperaemic myocardial blood flow (MBF) and MPR compared with those with controlled hypertension, while baseline MBF and coronary artery calcium (CAC) content were similar in both groups. After matching, there were no significant differences in clinical variables and coronary risk factors between patients with resistant and controlled hypertension, but patients with RH still had lower hyperaemic MBF and MPR (both P < 0.001). At univariable and multivariable linear regression analyses, age, RH, and CAC resulted significant predictors of lower MPR values (all P < 0.05). CONCLUSION: After balancing clinical characteristic by propensity score analysis, patients with RH had a blunted hyperaemic MBF and MPR compared with patients with controlled hypertension. The identification of impaired MPR could help to identify early structural alterations of the arterial walls in patients with RH.
AIMS: Impaired myocardial perfusion reserve (MPR) may occur earlier than coronary atherosclerosis and it may be an early manifestation of developing coronary artery disease (CAD) in patients with resistant hypertension (RH). We evaluated the relationship between RH and MPR in patients with systemic arterial hypertension after balancing for coronary risk factors. METHODS AND RESULTS: We studied 360 subjects without overt CAD and normal myocardial perfusion at stress-rest 82Rb positron emission tomography/computed tomography. To account for differences in baseline characteristics between patients with resistant and controlled hypertension, we created a propensity score-matched cohort considering clinical variables and coronary risk factors. Before matching, patients with RH were significantly older, had higher prevalence of male gender and hypercholesterolaemia, and showed significantly lower global hyperaemic myocardial blood flow (MBF) and MPR compared with those with controlled hypertension, while baseline MBF and coronary artery calcium (CAC) content were similar in both groups. After matching, there were no significant differences in clinical variables and coronary risk factors between patients with resistant and controlled hypertension, but patients with RH still had lower hyperaemic MBF and MPR (both P < 0.001). At univariable and multivariable linear regression analyses, age, RH, and CAC resulted significant predictors of lower MPR values (all P < 0.05). CONCLUSION: After balancing clinical characteristic by propensity score analysis, patients with RH had a blunted hyperaemic MBF and MPR compared with patients with controlled hypertension. The identification of impaired MPR could help to identify early structural alterations of the arterial walls in patients with RH.
Coronary vascular function in patients with resistant hypertension and normal myocardial perfusion: a propensity score analysis
| ▼ Noninvasive techniques for coronary flow reserve assessment |
Coronary vascular function in patients with resistant hypertension and normal myocardial perfusion: a propensity score analysis
Other filter: ([btitle,keywords] "Myocardial Blood Flo ...
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Impact Factor: 5.036
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Nappi C, Ponsiglione A, Acampa W, Gaudieri V, Zampella E, Assante R, Cuocolo R, Mannarino T, Dell'Aversana S, Petretta M, Imbriaco M, Cuocolo A
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Impact Factor: 5.26
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Assante R, Zampella E, Arumugam P, Acampa W, Imbriaco M, Tout D, Petretta M, Tonge C, Cuocolo A
* Quantitative relationship between coronary artery calcium and myocardial blood flow by hybrid rubidium-82 PET/CT imaging in patients with suspected coronary artery disease (578 views)
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Petretta M, Storto G, Pellegrino T, Bonaduce D, Cuocolo A
* Quantitative Assessment of Myocardial Blood Flow with SPECT (595 views)
Prog Cardiovasc Dis (ISSN: 0033-0620), 2015 Jan 3; 57(6): 607-614.
Impact Factor: 4.635
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Cuocolo A, Cittanti C, Acampa W, Larobina M, Petretta M
* Current and Future Status of Blood Flow Tracers (470 views)
Curr Cardiovasc Imaging Rep (ISSN: 1941-9066), 2011; 4(3): 227-236.
Impact Factor: 0
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Lucignani G, Cuocolo A
Advances in quantitative assessment of myocardial blood flow and coronary reserve (330 views)
Eur J Nucl Med (ISSN: 1619-7089, 1619-7070, 0340-6997), 2009 Oct; 36(10): 1687-1692.
Impact Factor: 4.531
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Petretta M, Soricelli A, Storto G, Cuocolo A
* Assessment of coronary flow reserve using single photon emission computed tomography with technetium 99m-labeled tracers (826 views)
J Nucl Cardiol (ISSN: 1532-6551, 1071-3581, 1532-6551electronic), 2008 May; 15(3): 456-465.
Impact Factor: 2.442
View Export to BibTeX Export to EndNote
* Myocardial perfusion reserve by using CZT: It's a long way to the top if you wanna standardize (261 views)
J Nucl Cardiol (ISSN: 1071-3581linking, 1532-6551electronic), 2021 Jun; 28(3): 885-887.
Impact Factor: 2.811
View Export to BibTeX Export to EndNote
Mannarino T, Gaudieri V, Acampa W
* Vasodilators and myocardial blood flow by CZT cameras: Make us see further (127 views)
J Nucl Cardiol (ISSN: 1071-3581linking, 1532-6551electronic), 2020 Nov 17; N/D: N/D-N/D.
Impact Factor: 3.847
View Export to BibTeX Export to EndNote
Zampella E, Acampa W, Assante R, Gaudieri V, Nappi C, Mannarino T, Mainolfi CG, Arumugam P, Petretta M, Cuocolo A
* Combined evaluation of regional coronary artery calcium and myocardial perfusion by (82)Rb PET/CT in predicting lesion-related outcome (215 views)
Eur J Nucl Med (ISSN: 1619-7070linking, 1619-7070print, 1619-7089electronic), 2020 Jul; 47(7): 1698-1704.
Impact Factor: 5.036
View Export to BibTeX Export to EndNote
Acampa W, Assante R, Mannarino T, Zampella E, D'Antonio A, Buongiorno P, Gaudieri V, Nappi C, Giordano A, Mainolfi CG, Petretta M, Cuocolo A
* Low-dose dynamic myocardial perfusion imaging by CZT-SPECT in the identification of obstructive coronary artery disease (241 views)
Eur J Nucl Med (ISSN: 1619-7070linking, 1619-7070print, 1619-7089electronic), 2020 Jul; 47(7): 1705-1712.
Impact Factor: 5.036
View Export to BibTeX Export to EndNote
Nappi C, Ponsiglione A, Acampa W, Gaudieri V, Zampella E, Assante R, Cuocolo R, Mannarino T, Dell'Aversana S, Petretta M, Imbriaco M, Cuocolo A
* Relationship between epicardial adipose tissue and coronary vascular function in patients with suspected coronary artery disease and normal myocardial perfusion imaging (300 views)
Eur Heart J-Card Img (ISSN: 2047-2404linking, 2047-2412), 2019 Jul 13; 20(12): 1379-1387.
Impact Factor: 5.26
View Export to BibTeX Export to EndNote
Assante R, Zampella E, Arumugam P, Acampa W, Imbriaco M, Tout D, Petretta M, Tonge C, Cuocolo A
* Quantitative relationship between coronary artery calcium and myocardial blood flow by hybrid rubidium-82 PET/CT imaging in patients with suspected coronary artery disease (578 views)
J Nucl Cardiol (ISSN: 1071-3581, 1532-6551, 1532-6551electronic), 2017; 24(2): 494-501.
Impact Factor: 4.011
View Export to BibTeX Export to EndNote
Petretta M, Storto G, Pellegrino T, Bonaduce D, Cuocolo A
* Quantitative Assessment of Myocardial Blood Flow with SPECT (595 views)
Prog Cardiovasc Dis (ISSN: 0033-0620), 2015 Jan 3; 57(6): 607-614.
Impact Factor: 4.635
View Export to BibTeX Export to EndNote
Cuocolo A, Cittanti C, Acampa W, Larobina M, Petretta M
* Current and Future Status of Blood Flow Tracers (470 views)
Curr Cardiovasc Imaging Rep (ISSN: 1941-9066), 2011; 4(3): 227-236.
Impact Factor: 0
View Export to BibTeX Export to EndNote
Lucignani G, Cuocolo A
Advances in quantitative assessment of myocardial blood flow and coronary reserve (330 views)
Eur J Nucl Med (ISSN: 1619-7089, 1619-7070, 0340-6997), 2009 Oct; 36(10): 1687-1692.
Impact Factor: 4.531
View Export to BibTeX Export to EndNote
Petretta M, Soricelli A, Storto G, Cuocolo A
* Assessment of coronary flow reserve using single photon emission computed tomography with technetium 99m-labeled tracers (826 views)
J Nucl Cardiol (ISSN: 1532-6551, 1071-3581, 1532-6551electronic), 2008 May; 15(3): 456-465.
Impact Factor: 2.442
View Export to BibTeX Export to EndNote
10 Records (9 excluding Abstracts).
Total impact factor: 37.609 (32.974 excluding Abstracts).
Total 5 year impact factor: 32.65 (28.762 excluding Abstracts).
Total impact factor: 37.609 (32.974 excluding Abstracts).
Total 5 year impact factor: 32.65 (28.762 excluding Abstracts).
267 views. Last view on Sunday 01 December 2024, 1:23:05
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