Multivariate fuzzy analysis of brain tissue volumes and relaxation rates for supporting the diagnosis of relapsing-remitting multiple sclerosis (524 views)
Biomedical Signal Processing And Control, 2019 Aug; 53: N/D-N/D.
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Paper type: Journal Article,
Impact factor: 2.943, 5-year impact factor: 3.321
Url: https://doi.org/10.1016/j.bspc.2019.101591
Keywords: Not available.
Affiliations:
*** IBB - CNR ***
Multiple Sclerosis (MS) is a chronic neuroinflammatory disorder of the brain and spinal cord, widely studied nowadays, due to its relevant prevalence in the population. Even though no cure exists, an earlier and more adequate choice of treatment could
References:
Not available.
Biomedical Signal Processing And Control, 2019 Aug; 53: N/D-N/D.
Export to BibTeX Export to EndNote
Paper type: Journal Article,
Impact factor: 2.943, 5-year impact factor: 3.321
Url: https://doi.org/10.1016/j.bspc.2019.101591
Keywords: Not available.
Affiliations:
*** IBB - CNR ***
Multiple Sclerosis (MS) is a chronic neuroinflammatory disorder of the brain and spinal cord, widely studied nowadays, due to its relevant prevalence in the population. Even though no cure exists, an earlier and more adequate choice of treatment could
delay its evolution and prevent irreversible sequelae and disability progression. Currently, Magnetic Resonance Imaging (MRI) represents an essential nonclinical tool for the detection of a hallmark of the disease, i.e. the presence of demyelinating lesions within cerebral white matter (WM), and, consequently, for the diagnosis of MS early within its course. However, errors in estimating lesions can contribute to a wrong diagnosis, if only the WM lesion load is taken into account, with a more relevant impact in individuals with a reduced lesion load at an initial clinical event, delaying the start of a treatment until a second clinical relapse or after confirming, successively, dissemination
References:
Not available.
Multivariate fuzzy analysis of brain tissue volumes and relaxation rates for supporting the diagnosis of relapsing-remitting multiple sclerosis
Multiple Sclerosis (MS) is a chronic neuroinflammatory disorder of the
brain and spinal cord, widely studied nowadays, due to its relevant
prevalence in the population. Even though no cure exists, an earlier and
more adequate choice of treatment could
Multiple Sclerosis (MS) is a chronic neuroinflammatory disorder of the
brain and spinal cord, widely studied nowadays, due to its relevant
prevalence in the population. Even though no cure exists, an earlier and
more adequate choice of treatment could
delay its
evolution and prevent irreversible sequelae and disability progression.
Currently, Magnetic Resonance Imaging (MRI) represents an essential
nonclinical tool for the detection of a hallmark of the disease, i.e.
the presence of demyelinating lesions within cerebral white matter (WM),
and, consequently, for the diagnosis of MS early within its course.
However, errors in estimating lesions can contribute to a wrong
diagnosis, if only the WM lesion load is taken into account, with a more
relevant impact in individuals with a reduced lesion load at an initial
clinical event, delaying the start of a treatment until a second clinical relapse or after confirming, successively, dissemination
In this context, this work proposes
an innovative system, employing a multivariate analysis approach, with
the aim of mining and integrating multiple sensitive neuroimaging
markers, including but not limited to the WM lesion load, into
classification models for supporting a more robust diagnosis of
Relapsing-Remitting-MS (RR-MS) already at an initial clinical event. To
this aim, a retrospective study of 81 patients with diagnosis of RR-MS
(39 males and 42 females, 37.3 ± 8.1 years old, age range 20–58) and 29
healthy people of comparable age and gender (15 males and 14 females,
39.7 ± 11.1 years old, age range 22–57) is used. All the individuals
were enrolled at Multiple Sclerosis Centre of the “Federico II”
University Hospital (Naples, Italy). A machine learning method based on
both statistics and Fuzzy Logic, already validated for its desirable
characteristics, is applied to volumetric
Multivariate fuzzy analysis of brain tissue volumes and relaxation rates for supporting the diagnosis of relapsing-remitting multiple sclerosis
| ▼ Relaxometry based MRI limb segmentation |
| ▼ Software development of digital MRI brain phantom |
| ▼ Relaxometry based MRI brain segmentation |
| ▼ Protein-based biotherapeutics |
Multivariate fuzzy analysis of brain tissue volumes and relaxation rates for supporting the diagnosis of relapsing-remitting multiple sclerosis
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Megna R, Alfano B, Lanzillo R, Costabile T, Comerci M, Vacca G, Carotenuto A, Moccia M, Servillo G, Prinster A, Brescia Morra V, Quarantelli M
* Brain tissue volumes and relaxation rates in multiple sclerosis: implications for cognitive impairment (388 views) (PDF 51 views)
J Neurol (ISSN: 1432-1459electronic, 0340-5354linking, 0340-5354print), 2019 Feb; 266(2): 361-368.
Impact Factor: 3.853
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Martinez-fernandez L, Pepino AJ, Segarra-marti J, Jovaisaite J, Vaya I, Nenov A, Markovitsi D, Gustavsson T, Banyasz A, Garavelli M, Improta R
* Photophysics of Deoxycytidine and 5-Methyldeoxycytidine in Solution: A Comprehensive Picture by Quantum Mechanical Calculations and Femtosecond Fluorescence Spectroscopy (353 views)
J Am Chem Soc (ISSN: 0002-7863, 0002-2786, 0002-7863print), 2017 Jun 14; 139(23): 7780-7791.
Impact Factor: 14.357
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Tedeschi E, Palma G, Canna A, Cocozza S, Russo C, Borrelli P, Lanzillo R, Angelini V, Postiglione E, Morra VB, Salvatore M, Brunetti A, Quarantelli M
* In vivo dentate nucleus MRI relaxometry correlates with previous administration of Gadolinium-based contrast agents (649 views)
Eur Radiol (ISSN: 0938-7994, 1432-1084electronic, 0938-7994linking), 2016 Feb 23; 26(12): 4577-4584.
Impact Factor: 3.967
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Cella L, D'Avino V, Palma G, Conson M, Liuzzi R, Picardi M, Pressello MC, Boboc GI, Battistini R, Donato V, Pacelli R
* Modeling the risk of radiation-induced lung fibrosis: Irradiated heart tissue is as important as irradiated lung (778 views) (PDF 230 views)
Radiother Oncol (ISSN: 0167-8140, 1879-0887, 0167-8140linking), 2015 Aug 12; 117(1): 36-43.
Impact Factor: 4.817
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D'Avino V, Palma G, Liuzzi R, Conson M, Doria F, Salvatore M, Pacelli R, Cella L
* Prediction of gastrointestinal toxicity after external beam radiotherapy for localized prostate cancer (558 views)
Radiat Oncol (ISSN: 1748-717x), 2015 Apr 8; 10(1): 80-80.
Impact Factor: 2.466
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Diana D, Russomanno A, De Rosa L, Di Stasi R, Capasso D, Di Gaetano S, Romanelli A, Russo L, D'Andrea LD, Fattorusso R
* Functional Binding Surface Of A Beta-Hairpin Vegf Receptor Targeting Peptide Determined By Nmr Spectroscopy In Living Cells (572 views)
Chemistry (ISSN: 0947-6539, 1521-3765, 1521-3765electronic), 2015 Jan 2; 21(1): 91-95.
Impact Factor: 5.771
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Zhang Y, Improta R, Kohler B
Mode-specific vibrational relaxation of photoexcited guanosine 5'-monophosphate and its acid form: a femtosecond broadband mid-IR transient absorption and theoretical study (383 views)
Phys Chem Chem Phys (ISSN: 1463-9076, 1463-3907, 1463-9084electronic), 2014 Jan 28; 16(4): 1487-1499.
Impact Factor: 4.493
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Cella L, Liuzzi R, D'Avino V, Frezza A, Conson M, Pugliese N, Picardi M, Salvatore M, Pacelli R
* Multivariate Ntcp Modeling Of Radiation Damage To The Cardiopulmonary System: The Hodgkin Lymphoma Paradigm (393 views)
Radiother Oncol (ISSN: 0167-8140, 1879-0887, 0167-8140linking), 2014; 111: 340-340.
Impact Factor: 4.363
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Greco A, Ragucci M, Coda ARD, Rosa A, Gargiulo S, Liuzzi R, Gramanzini M, Albanese S, Pappata S, Mancini M, Brunetti A, Salvatore M
* High frequency ultrasound for in vivo pregnancy diagnosis and staging of placental and fetal development in mice (549 views)
Plosone (ISSN: 1932-6203, 1932-6203electronic, 1932-6203linking), 2013 Oct 14; 8(10): e77205-e77205.
Impact Factor: 3.534
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Cella L, Liuzzi R, Conson M, D'Avino V, Salvatore M, Pacelli R
* Multivariate normal tissue complication probability modeling of heart valve dysfunction in Hodgkin lymphoma survivors (535 views)
Int J Radiat Oncol (ISSN: 0360-3016, 1879-355x, 1879-355xelectronic), 2013 Oct 1; 87(2): 304-310.
Impact Factor: 4.176
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Cella L, D'Avino V, Liuzzi R, Conson M, Doria F, Faiella A, Loffredo F, Salvatore M, Pacelli R
* Multivariate normal tissue complication probability modeling of gastrointestinal toxicity after external beam radiotherapy for localized prostate cancer (682 views)
Radiation Oncology (ISSN: 1748-717x), 2013 Sep 23; 8(1): 221-221.
Impact Factor: 2.36
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Giacomobono S, Gallicchio R, Capacchione D, Nardelli A, Gattozzi D, Lettini G, Molinari L, Mainenti P, Cammarota A, Storto G
* F-18 FDG PET/CT in the assessment of patients with unexplained CEA rise after surgical curative resection for colorectal cancer (491 views)
International Journal Of Colorectal Disease (ISSN: 0179-1958, 0179-1958linking), 2013 Jul 12; 28(12): 1699-1705.
Impact Factor: 2.415
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Catanzaro V, Gringeri CV, Menchise V, Padovan S, Boffa C, Dastru W, Chaabane L, Digilio G, Aime S
* A R2p/R1p ratiometric procedure to assess matrix metalloproteinase-2 activity by magnetic resonance imaging (570 views)
Angew Chem Int Ed (ISSN: 1433-7851, 1521-3773electronic, 1433-7851linking), 2013 Apr 2; 52(14): 3926-3930.
Impact Factor: 11.336
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Acampa W, Petretta M, Daniele S, Del Prete G, Assante R, Zampella E, Cuocolo A
* Incremental prognostic value of stress myocardial perfusion imaging in asymptomatic diabetic patients (640 views)
Atherosclerosis (ISSN: 0021-9150, 1879-1484), 2013 Apr; 227(2): 307-312.
Impact Factor: 3.971
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Banyasz A, Gustavsson T, Onidas D, Changenet-Barret P, Markovitsi D, Improta R
* Multi-pathway excited state relaxation of adenine oligomers in aqueous solution: A joint theoretical and experimental study (575 views)
Chemistry (ISSN: 0947-6539, 1521-3765, 1521-3765electronic), 2013 Mar; 19(11): 3762-3774.
Impact Factor: 5.696
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Petretta M, Acampa W, Daniele S, Petretta MP, Nappi C, Assante R, Zampella E, Costanzo P, Perrone-Filardi P, Cuocolo A
* Transient ischemic dilation in SPECT myocardial perfusion imaging for prediction of severe coronary artery disease in diabetic patients (1223 views)
J Nucl Cardiol (ISSN: 1071-3581, 1532-6551, 1532-6551electronic), 2013 Feb; 20(1): 45-52.
Impact Factor: 2.645
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Cella L, Liuzzi R, Conson M, D'Avino V, Salvatore M, Pacelli R
* Development of multivariate NTCP models for radiation-induced hypothyroidism: A comparative analysis (599 views) (PDF 265 views)
Radiat Oncol Radiation Oncology (ISSN: 1748-717x), 2012 Dec 27; 7(1): 224-224.
Impact Factor: 2.107
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Palma G, Greco D, Innocenti S, Alfano B
* Method Of Generating 2d Or 3d Maps Of Mri T1 And T2 Relaxation Times (376 views) (PDF 223 views)
Patentsofficial Gazette Of The United States Patent And Trademark Office, 2012 Sep 05; 20120223710: 18-18.
Impact Factor: 0
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Petretta M, Daniele S, Acampa W, Imbriaco M, Pellegrino T, Messalli G, Xhoxhi E, Del Prete G, Nappi C, Accardo D, Angeloni F, Bonaduce D, Cuocolo A
* Prognostic value of coronary artery calcium score and coronary CT angiography in patients with intermediate risk of coronary artery disease (854 views)
Int J Card Imaging (ISSN: 1569-5794, 1875-8312), 2012 Sep; 28(6): 1547-1556.
Impact Factor: 2.648
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Hua Y, Changenet-Barret P, Improta R, Vaya I, Gustavsson T, Kotlyar AB, Zikich D, Sket P, Plavec J, Markovitsi D
* Cation effect on the electronic excited states of guanine nanostructures studied by time-resolved fluorescence spectroscopy (515 views)
J Phys Chem C (ISSN: 1932-7447), 2012 Jul 12; 116(27): 14682-14689.
Impact Factor: 4.814
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Cella L, Conson M, Caterino M, De Rosa N, Liuzzi R, Picardi M, Grimaldi F, Solla R, Farella A, Salvatore M, Pacelli R
* Thyroid V30 predicts radiation-induced hypothyroidism in patients treated with sequential chemo-radiotherapy for Hodgkin's lymphoma (628 views) (PDF 265 views)
Int J Radiat Oncol (ISSN: 0360-3016, 1879-355x, 1879-355xelectronic), 2012 Apr 1; 82(5): 1802-1808.
Impact Factor: 4.524
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Messalli G, Imbriaco M, Avitabile G, Russo R, Iodice D, Spinelli L, Dellegrottaglie S, Cademartiri F, Salvatore M, Pisani A
* Role of cardiac MRI in evaluating patients with Anderson-Fabry disease: Assessing cardiac effects of long-term enzyme replacement therapy (427 views)
Radiol Med (ISSN: 0033-8362, 1826-6983, 1826-6983electronic), 2012 Feb; 117(1): 19-28.
Impact Factor: 1.461
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Alfano B, Comerci M, Larobina M, Prinster A, Hornak JP, Selvan SE, Amato U, Quarantelli M, Tedeschi G, Brunetti A, Salvatore M
* An MRI digital brain phantom for validation of segmentation methods (796 views) (PDF 714 views)
Med Image Anal (ISSN: 1361-8415, 1361-8423, 1361-8415linking), 2011 Jun; 15(3): 329-339.
Impact Factor: 4.424
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Pedone C, Napoli N, Pozzilli P, Rossi FF, Lauretani F, Bandinelli S, Ferrucci L, Antonelli-Incalzi R
* Dietary pattern and bone density changes in elderly women: a longitudinal study (695 views)
J Am Coll Nutr (ISSN: 1541-1087, 0731-5724), 2011 Apr; 30(2): 149-154.
Impact Factor: 2.29
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Imbriaco M, Pisani A, Spinelli L, Cuocolo A, Messalli G, Capuano E, Marmo M, Liuzzi R, Visciano B, Cianciaruso B, Salvatore M
* Effects of enzyme-replacement therapy in patients with Anderson-Fabry disease: a prospective long-term cardiac magnetic resonance imaging study (769 views)
Heart (ISSN: 1355-6037, 1468-201x), 2009 Jul; 95(13): 1103-1107.
Impact Factor: 5.385
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Tedeschi G, Dinacci D, Comerci M, Lavorgna L, Savettieri G, Quattrone A, Livrea P, Patti F, Morra VB, Servillo G, Orefice G, Paciello M, Prinster A, Coniglio G, Bonavita S, Di Costanzo A, Bellacosa A, Valentino P, Quarantelli M, Brunetti A, Salemi G, D , #xamelio M, Simone I, Salvatore M, Bonavita V, Alfano B
* Brain atrophy evolution and lesion load accrual in multiple sclerosis: a 2-year follow-up study (614 views) (PDF 286 views)
Mult Scler (ISSN: 1352-4585, 1477-0970, 1352-4585linking), 2009 Feb; 15(2): 204-211.
Impact Factor: 3.279
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Karunakaran V, Kleinermanns K, Improta R, Kovalenko SA
* Photoinduced dynamics of guanosine monophosphate in water from broad-band transient absorption spectroscopy and quantum-chemical calculations (408 views)
J Am Chem Soc (ISSN: 0002-7863, 0002-2786, 1520-5126), 2009; 131(16): 5839-5850.
Impact Factor: 8.58
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Pedone C, Di Pasquale G, Greco C, Gonzini L, Maggioni AP, Pavesi PC, Sabini A, Boccanelli A; In-Acs Outcome Investigators
* Prescription at discharge of recommended treatments for secondary prevention in patients with ST-segment elevation myocardial infarction according to reperfusion strategies. Results from the IN-ACS outcome study (590 views)
Acute Cardiac Care (ISSN: 1748-295x, 1748-2941), 2009; 11(4): 222-228.
Impact Factor: 0
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Gallotta G, Palmieri V, Piedimonte V, Rendina D, De Bonis S, Russo V, Celentano A, Di Minno M, Postiglione A, Di Minno G
* Increased troponin I predicts in-hospital occurrence of hemodynamic instability in patients with sub-massive or non-massive pulmonary embolism independent to clinical, echocardiographic and laboratory information (955 views)
Int J Cardiol (ISSN: 0167-5273, 1874-1754electronic, 0167-5273linking), 2008 Mar 14; 124(3): 351-357.
Impact Factor: 3.121
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Frasca F, Nucera C, Pellegriti G, Gangemi P, Attard M, Stella M, Loda M, Vella V, Giordano C, Trimarchi F, Mazzoni E, Belfiore A, Vigneri R
* BRAF(V600E) mutation and the biology of papillary thyroid cancer (900 views)
Endocr Relat Cancerendocrine Related Cancer (ISSN: 1351-0088), 2008; 15(1): 191-205.
Impact Factor: 5.236
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Tedeschi G, Dinacci D, Lavorgna L, Prinster A, Savettieri G, Quattrone A, Livrea P, Messina C, Reggio A, Servillo G, Bresciamorra V, Orefice G, Paciello M, Brunetti A, Paolillo A, Coniglio G, Bonavita S, Di Costanzo A, Bellacosa A, Valentino P, Quarantelli M, Patti F, Salemi G, Cammarata E, Simone I, Salvatore M, Bonavita V, Alfano B
* Correlation between fatigue and brain atrophy and lesion load in multiple sclerosis patients independent of disability (818 views) (PDF 284 views)
J Neurol Sci (ISSN: 0022-510x, 0022-510xlinking), 2007 Dec 15; 263(1-2): 15-19.
Impact Factor: 2.315
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Improta R, Scalmani G, Frisch MJ, Barone V
* Toward effective and reliable fluorescence energies in solution by a new state specific polarizable continuum model time dependent density functional theory approach (849 views)
J Chem Phys (ISSN: 0021-9606, 0897-690online), 2007 Sep 21; 127(7): N/D-N/D.
Impact Factor: 3.044
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Imbriaco M, Spinelli L, Cuocolo A, Maurea S, Sica G, Quarantelli M, Pisani A, Liuzzi R, Cianciaruso B, Sabbatini M, Salvatore M
* MRI characterization of myocardial tissue in patients with Fabry's disease (840 views)
Ajr Am J Roentgenol (ISSN: 1546-3141, 0361-803x, 1546-3141electronic), 2007 Mar; 188(3): 850-853.
Impact Factor: 2.47
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Maestri R, Pinna G, Accardo A, Allegrini P, Balocchi R, D'ADDIO G, Ferrario M, Menicucci D, Porta A, Sassi R
* Nonlinear indices of heart rate variability in chronic heart failure patients: Redundancy and comparative clinical value (508 views)
J Cardiovasc Electrophysiol (ISSN: 1045-3873), 2007; 18(4): 425-433.
Impact Factor: 3.475
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Improta R, Barone V, Scalmani G, Frisch MJ
* A state-specific polarizable continuum model time dependent density functional theory method for excited state calculations in solution (481 views)
J Chem Phys (ISSN: 0021-9606, 0897-690online), 2006 Sep 7; 125(5): N/D-N/D.
Impact Factor: 3.166
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Picardi M, Ciancia R, De Renzo A, Montante B, Ciancia G, Zeppa P, Lobello R, Pane F, D'Agostino D, Nicolai E, Sirignano C, Salvatore M, Rotoli B
* Estimation of bulky lymph nodes by power Doppler ultrasound scanning in patients with Hodgkin's lymphoma: A prospective study (452 views)
Haematologica (ISSN: 0390-6078, 0006-4971, 0006-6497), 2006 Jul; 91(7): 960-963.
Impact Factor: 5.032
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Palmieri V, Storto G, Arezzi E, Pellegrino T, Mancini M, Di Minno G, Ferrara AL, Cuocolo A, Celentano A
* Relations of left ventricular mass and systolic function to endothelial function and coronary flow reserve in healthy, new discovered hypertensive subjects (442 views)
J Hum Hypertens (ISSN: 0950-9240), 2005 Dec; 19(12): 941-950.
Impact Factor: 2.405
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Amato U, Larobina M, Antoniadis A, Alfano B
* Segmentation of magnetic resonance brain images through discriminant analysis (790 views) (PDF 275 views)
J Neurosci Methods (ISSN: 0165-0270, 0165-0270linking, 1872-678xelectronic), 2003 Dec 30; 131(1-2): 65-74.
Impact Factor: 1.777
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D'Auria G, Flores G, Falcigno L, Oliva R, Vacatello M, Corsaro MM, Parrilli M, Paolillo L
* Hyaluronate tetrasaccharide-Cu(II) interaction: A NMR study (441 views)
Biopolymers (ISSN: 0006-3525, 0006-6352, 0006-3525print), 2003 Oct; 70(2): 260-269.
Impact Factor: 2.733
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Leosco D, Iaccarino G, Cipolletta E, De Santis D, Pisani E, Trimarco V, Ferrara N, Abete P, Sorriento D, Rengo F, Trimarco B
* Exercise restores β-adrenergic vasorelaxation in aged rat carotid arteries (460 views)
Am J Physiol Heart Circ Physiol American Journal Of Physiology Heart And Circulatory Physiology (ISSN: 0363-6135), 2003; 285(154-1): H369-H369.
Impact Factor: 3.658
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Ciarmiello A, Brunetti A, Larobina M, Quarantelli M, Ziviello M, Alfano B, Salvatore M
* Assessment of scanner performance and normalization of estimated relaxation rate values (487 views) (PDF 263 views)
Magn Reson Imaging (ISSN: 0730-725x), 2001 Jan; 19(1): 123-128.
Impact Factor: 2.037
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Spinelli L, Petretta M, Cuocolo A, Nicolai E, Acampa W, Vicario L, Bonaduce D
Prediction of recovery of left ventricular dysfunction after acute myocardial infarction: Comparison between Tc-99m-sestamibi cardiac tomography and low-dose dobutamine echocardiography (366 views)
J Nucl Med (ISSN: 0161-5505, 1535-5667, 1535-5667electronic), 1999 Oct; 40(10): 1683-1692.
Impact Factor: 3.326
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Betocchi S, Piscione F, Perrone-Filardi P, Pace L, Cappelli-Bigazzi M, Alfano B, Ciarmiello A, Salvatore M, Condorelli M, Chiariello M
Effects of intravenous verapamil on left ventricular relaxation and filling in stable angina pectoris (676 views)
Am J Cardiol (ISSN: 0002-9149), 1990 Oct 1; 66(10): 818-825.
Impact Factor: 2.402
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48 Records (44 excluding Abstracts).
Total impact factor: 193.337 (182.764 excluding Abstracts).
Total 5 year impact factor: 198.827 (188.14 excluding Abstracts).
Total impact factor: 193.337 (182.764 excluding Abstracts).
Total 5 year impact factor: 198.827 (188.14 excluding Abstracts).
524 views. Last view on Tuesday 10 December 2024, 12:07:29
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