Differential diagnosis of pancreatic cysts: A prospective study on the role of intra-cystic glucose concentration (143 views)
Dig Liver Dis (ISSN: 1590-8658linking), 2020 Sep; 52(9): 1026-1032.
Export to BibTeX Export to EndNote
Paper type: Journal Article,
Impact factor: 3.57, 5-year impact factor: 2.871
Url: Not available.
Keywords: Cea, Glucose, Intraductal Papillary Mucinous Neoplasm, Mucinous Cystadenoma, Pancreatic Cysts, Serous Cystadenoma,
Affiliations:
*** IBB - CNR ***
Department of Medical Sciences, Division of Gastroenterology, University of Torino, Torino, Italy. Electronic address: davidegiuseppe.ribaldone@unito.it.
Department of General and Specialist Medicine, Gastroenterologia-U, Città della Salute e della Scienza di Torino, C.so Bramante 88, 10126 Turin, Italy.
Department of Laboratory Medicine, Città della Salute e della Scienza di Torino, C.so Bramante 88, 10126 Turin, Italy.
Institute of Biostructure and Bioimaging, CNR c/o Molecular Biotechnology Centre, 10126 Turin, Italy.
References:
Not available.
Dig Liver Dis (ISSN: 1590-8658linking), 2020 Sep; 52(9): 1026-1032.
Export to BibTeX Export to EndNote
Paper type: Journal Article,
Impact factor: 3.57, 5-year impact factor: 2.871
Url: Not available.
Keywords: Cea, Glucose, Intraductal Papillary Mucinous Neoplasm, Mucinous Cystadenoma, Pancreatic Cysts, Serous Cystadenoma,
Affiliations:
*** IBB - CNR ***
Department of Medical Sciences, Division of Gastroenterology, University of Torino, Torino, Italy. Electronic address: davidegiuseppe.ribaldone@unito.it.
Department of General and Specialist Medicine, Gastroenterologia-U, Città della Salute e della Scienza di Torino, C.so Bramante 88, 10126 Turin, Italy.
Department of Laboratory Medicine, Città della Salute e della Scienza di Torino, C.so Bramante 88, 10126 Turin, Italy.
Institute of Biostructure and Bioimaging, CNR c/o Molecular Biotechnology Centre, 10126 Turin, Italy.
References:
Not available.
Differential diagnosis of pancreatic cysts: A prospective study on the role of intra-cystic glucose concentration
BACKGROUND: The accuracy and costs of current diagnostic methods in the differential diagnosis of pancreatic cystic lesions still has ample room for improvement. AIMS: The aim of the study was to confirm the diagnostic yield of intracystic glucose in the diagnosis of pancreatic cyst subtypes. METHODS: We prospectively recruited all patients who underwent Endoscopic Ultrasound with Fine Needle Aspiration of pancreatic cyst at our Institution. RESULTS: Fifty-six patients were included in the study. We found that intracystic glucose concentration < 50 mg/dL was significantly more sensitive than a concentration of Carcinoembryonic Antigen >
192 ng/mL (93.6% vs 54.8%; p = 0.003) for the diagnosis of mucinous cysts. In terms of specificity, the two markers were not different (96% vs 100%; p = 1). Regarding the diagnosis of non-mucinous cysts, intracystic glucose concentration ≥ 50 mg/mL showed higher sensitivity than Carcinoembryonic Antigen level < 5 ng/mL (96% vs 72%) although a statistical significance could not be reached (p = 0.07). The two markers were not statistically different in terms of specificity (93.6% vs 87.1%; p = 0.62). CONCLUSION: Given its diagnostic performance and ease of measurement, intracystic glucose may replace Carcinoembryonic Antigen in the differential diagnosis of mucinous versus non-mucinous pancreatic cysts.
BACKGROUND: The accuracy and costs of current diagnostic methods in the differential diagnosis of pancreatic cystic lesions still has ample room for improvement. AIMS: The aim of the study was to confirm the diagnostic yield of intracystic glucose in the diagnosis of pancreatic cyst subtypes. METHODS: We prospectively recruited all patients who underwent Endoscopic Ultrasound with Fine Needle Aspiration of pancreatic cyst at our Institution. RESULTS: Fifty-six patients were included in the study. We found that intracystic glucose concentration < 50 mg/dL was significantly more sensitive than a concentration of Carcinoembryonic Antigen >
192 ng/mL (93.6% vs 54.8%; p = 0.003) for the diagnosis of mucinous cysts. In terms of specificity, the two markers were not different (96% vs 100%; p = 1). Regarding the diagnosis of non-mucinous cysts, intracystic glucose concentration ≥ 50 mg/mL showed higher sensitivity than Carcinoembryonic Antigen level < 5 ng/mL (96% vs 72%) although a statistical significance could not be reached (p = 0.07). The two markers were not statistically different in terms of specificity (93.6% vs 87.1%; p = 0.62). CONCLUSION: Given its diagnostic performance and ease of measurement, intracystic glucose may replace Carcinoembryonic Antigen in the differential diagnosis of mucinous versus non-mucinous pancreatic cysts.
Differential diagnosis of pancreatic cysts: A prospective study on the role of intra-cystic glucose concentration
No results. |
Differential diagnosis of pancreatic cysts: A prospective study on the role of intra-cystic glucose concentration
Other filter: ([btitle,keywords] "Intraductal Papillar ...
Maurea S, Fusari M, Imbriaco M, Camera L, Mainenti PP, Campione S, Santangelo M, Salvatore M
* Pitfalls in diagnostic imaging of cystic pancreatic masses: a case of true cystic lesion mimicking a mucinous cystadenoma (399 views)
Jop (ISSN: 1590-8577, 1590-0857), 2012 Jan 10; 13(1): 83-86.
Impact Factor: 0
View Export to BibTeX Export to EndNote
* Pitfalls in diagnostic imaging of cystic pancreatic masses: a case of true cystic lesion mimicking a mucinous cystadenoma (399 views)
Jop (ISSN: 1590-8577, 1590-0857), 2012 Jan 10; 13(1): 83-86.
Impact Factor: 0
View Export to BibTeX Export to EndNote
1 Records (1 excluding Abstracts).
Total impact factor: 0 (0 excluding Abstracts).
Total 5 year impact factor: 0 (0 excluding Abstracts).
Total impact factor: 0 (0 excluding Abstracts).
Total 5 year impact factor: 0 (0 excluding Abstracts).
143 views. Last view on Saturday 30 November 2024, 23:48:25
ibb.cnr.it
