Dietary influence on adiponectin in patients with type 2 diabetes (334 views)
Eur J Clin Invest (ISSN: 0014-2972linking, 1365-2362), 2021 Aug; 51(8): e13548-N/D.
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Paper type: Journal Article,
Impact factor: 3.086, 5-year impact factor: 2.759
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Keywords: Adiponectin, Dietary Fibres, Glycaemic Index, Liver Fat, Monounsaturated Fatty Acids, Type 2 Diabetes,
Affiliations:
*** IBB - CNR ***
Department of Clinical Medicine and Surgery, Federico II University, Naples, Italy.
Dipartimento di Sanità Pubblica, Università degli Studi di Napoli Federico II, Naples, Italy.
CEINGE-Biotecnologie Avanzate Scarl, Naples, Italy.
Dipartimento di Scienze e Tecnologie Ambientali, Biologiche, Farmaceutiche, Università della Campania "Luigi Vanvitelli", Caserta, Italy.
Institute of Biostructure and Bioimaging, National Research Council, Naples, Italy.
References:
Not available.
Eur J Clin Invest (ISSN: 0014-2972linking, 1365-2362), 2021 Aug; 51(8): e13548-N/D.
Export to BibTeX Export to EndNote
Paper type: Journal Article,
Impact factor: 3.086, 5-year impact factor: 2.759
Url: Not available.
Keywords: Adiponectin, Dietary Fibres, Glycaemic Index, Liver Fat, Monounsaturated Fatty Acids, Type 2 Diabetes,
Affiliations:
*** IBB - CNR ***
Department of Clinical Medicine and Surgery, Federico II University, Naples, Italy.
Dipartimento di Sanità Pubblica, Università degli Studi di Napoli Federico II, Naples, Italy.
CEINGE-Biotecnologie Avanzate Scarl, Naples, Italy.
Dipartimento di Scienze e Tecnologie Ambientali, Biologiche, Farmaceutiche, Università della Campania "Luigi Vanvitelli", Caserta, Italy.
Institute of Biostructure and Bioimaging, National Research Council, Naples, Italy.
References:
Not available.
Dietary influence on adiponectin in patients with type 2 diabetes
BACKGROUND: Here, we evaluate the effects of a diet rich in low-glycaemic index carbohydrates and fibre (CHO/Fibre diet) or monounsaturated fatty acids (MUFA diet), on fasting and postprandial adiponectin concentrations and their relationship with the beneficial effects of the experimental diets on postprandial glucose metabolism and liver fat in type 2 diabetes (T2D). METHODS: Fasting and postprandial adiponectin plasma concentrations were measured before and after dietary interventions in the participants to a randomized controlled trial (NCT01025856), wherein 37 men and 8 women with T2D, aged 35-70 years, followed a CHO/Fibre diet or a MUFA diet for an 8-week period. Hepatic fat content by (1) H NMR and fasting and postprandial plasma glucose and insulin measurements were also available. RESULTS: Fasting adiponectin plasma levels did not change after both diets. Postprandial adiponectin significantly increased after the CHO/fibre diet (9.9 ± 1.6 μg/mL vs. 10.8 ± 2.3 μg/mL; P = .033) but not after the MUFA diet (10.6 ± 1.8 μg/mL vs. 10.6 ± 1.6 μg/mL; P = .935) with a significant difference between changes (P = .035). In the combined CHO/Fibre and MUFA groups, fasting and postprandial adiponectin significantly and inversely correlated with postprandial insulin iAUC at baseline and after intervention, and with liver fat content after intervention. CONCLUSIONS: A diet rich in CHO/Fibre increased postprandial plasma adiponectin significantly more than a MUFA diet in patients with T2D. Independently of diet, adiponectin levels associated with postprandial insulin concentrations. The dietary interventions modulated the relationship between adiponectin and liver fat.
BACKGROUND: Here, we evaluate the effects of a diet rich in low-glycaemic index carbohydrates and fibre (CHO/Fibre diet) or monounsaturated fatty acids (MUFA diet), on fasting and postprandial adiponectin concentrations and their relationship with the beneficial effects of the experimental diets on postprandial glucose metabolism and liver fat in type 2 diabetes (T2D). METHODS: Fasting and postprandial adiponectin plasma concentrations were measured before and after dietary interventions in the participants to a randomized controlled trial (NCT01025856), wherein 37 men and 8 women with T2D, aged 35-70 years, followed a CHO/Fibre diet or a MUFA diet for an 8-week period. Hepatic fat content by (1) H NMR and fasting and postprandial plasma glucose and insulin measurements were also available. RESULTS: Fasting adiponectin plasma levels did not change after both diets. Postprandial adiponectin significantly increased after the CHO/fibre diet (9.9 ± 1.6 μg/mL vs. 10.8 ± 2.3 μg/mL; P = .033) but not after the MUFA diet (10.6 ± 1.8 μg/mL vs. 10.6 ± 1.6 μg/mL; P = .935) with a significant difference between changes (P = .035). In the combined CHO/Fibre and MUFA groups, fasting and postprandial adiponectin significantly and inversely correlated with postprandial insulin iAUC at baseline and after intervention, and with liver fat content after intervention. CONCLUSIONS: A diet rich in CHO/Fibre increased postprandial plasma adiponectin significantly more than a MUFA diet in patients with T2D. Independently of diet, adiponectin levels associated with postprandial insulin concentrations. The dietary interventions modulated the relationship between adiponectin and liver fat.
Dietary influence on adiponectin in patients with type 2 diabetes
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Dietary influence on adiponectin in patients with type 2 diabetes
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View Export to BibTeX Export to EndNote
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Impact Factor: 0.629
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Testino G, Leone S, Fagoonee S, Del Bas JM, Rodriguez B, Puiggros F, Marine S, Rodriguez MA, Morina D, Armengol L, Caimari A, Arola L, Cimini FA, Barchetta I, Carotti S, Bertoccini L, Baroni MG, Vespasiani-gentilucci U, Cavallo MG, Morini S, Nelson JE, Roth CL, Wilson LA, Yates KP, Aouizerat B, Morgan-stevenson V, Whalen E, Hoofnagle A, Mason M, Gersuk V, Yeh MM, Kowdley KV, Lee SM, Jun DW, Cho YK, Jang KS, Kucukazman M, Ata N, Dal K, Yeniova AO, Kefeli A, Basyigit S, Aktas B, Akin KO, Agladioglu K, Ure OS, Topal F, Nazligul Y, Beyan E, Ertugrul DT, Catena C, Cosma C, Camozzi V, Plebani M, Ermani M, Sechi LA, Fallo F, Goto Y, Ray MB, Mendenhall CL, French SW, Gartside PS
Serum vitamin A deficiency and increased intrahepatic expression of cytokeratin antigen in alcoholic liver disease (692 views)
Hepatology (ISSN: 1827-1669electronic, 0026-4806linking), 1988 Sep; 83120693611123109(5): 1019-1026.
Impact Factor: 0.913
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26 Records (22 excluding Abstracts).
Total impact factor: 94.153 (77.986 excluding Abstracts).
Total 5 year impact factor: 86.277 (73.64 excluding Abstracts).
Total impact factor: 94.153 (77.986 excluding Abstracts).
Total 5 year impact factor: 86.277 (73.64 excluding Abstracts).
334 views. Last view on Sunday 06 October 2024, 13:49:30
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